Homo sapiens

0 known processes

PKNOX1

PBX/knotted 1 homeobox 1

(Aliases: pkonx1c,PREP1)

PKNOX1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.161
peripheral nervous system developmentGO:000742220.121
regulation of cell differentiationGO:00455953930.079
intracellular protein transportGO:00068862700.077
cytoplasmic transportGO:00164823790.067
circulatory system developmentGO:00723592620.065
Mouse
protein localization to organelleGO:00333652800.061
single organism cellular localizationGO:19025803320.060
cellular amino acid metabolic processGO:00065201160.057
cellular ketone metabolic processGO:0042180800.056
regulation of sequence specific dna binding transcription factor activityGO:00510902110.053
cardiovascular system developmentGO:00723582620.053
Mouse
nucleocytoplasmic transportGO:00069131760.052
nervous system developmentGO:00073992930.050
cellular amine metabolic processGO:0044106410.049
amine metabolic processGO:0009308440.049
regulation of cellular ketone metabolic processGO:0010565500.049
cell developmentGO:00484683280.048
multicellular organismal agingGO:001025930.046
positive regulation of cellular amino acid metabolic processGO:004576430.046
regulation of cellular amine metabolic processGO:0033238110.044
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.044
protein targeting to nucleusGO:00447441040.043
determination of adult lifespanGO:000834020.043
positive regulation of cellular amine metabolic processGO:003324070.042
establishment of protein localization to organelleGO:00725941720.042
protein targetingGO:00066051870.042
female gamete generationGO:000729220.041
embryonic retina morphogenesis in camera type eyeGO:006005910.041
nuclear transportGO:00511691790.041
regulation of cellular amino acid metabolic processGO:000652160.040
oogenesisGO:004847720.039
protein localization to nucleusGO:00345041360.037
locomotory behaviorGO:000762610.037
small gtpase mediated signal transductionGO:0007264780.036
protein importGO:00170381300.035
organophosphate catabolic processGO:00464344300.035
negative regulation of protein metabolic processGO:00512483910.034
purine ribonucleoside metabolic processGO:00461284370.034
organ morphogenesisGO:00098871470.033
purine containing compound catabolic processGO:00725234110.033
purine ribonucleotide catabolic processGO:00091544040.032
negative regulation of cellular protein metabolic processGO:00322693530.032
ribonucleoside catabolic processGO:00424544060.032
protein import into nucleusGO:00066061040.031
single organism nuclear importGO:19025931040.031
purine nucleoside triphosphate metabolic processGO:00091444120.031
lipid metabolic processGO:00066293810.030
nucleoside triphosphate catabolic processGO:00091433940.030
purine ribonucleoside catabolic processGO:00461303980.030
ribonucleotide catabolic processGO:00092614050.030
nucleoside catabolic processGO:00091644080.030
ribonucleoside triphosphate catabolic processGO:00092033910.030
nuclear importGO:00511701060.030
purine nucleoside catabolic processGO:00061523980.029
regulation of cell cycleGO:00517263930.029
cellular macromolecule catabolic processGO:00442653800.029
tissue morphogenesisGO:0048729960.029
purine nucleoside triphosphate catabolic processGO:00091463920.029
glycosyl compound catabolic processGO:19016584130.029
nucleotide catabolic processGO:00091664080.028
regulation of transferase activityGO:00513383550.028
cell adhesionGO:00071553250.028
neuromuscular junction developmentGO:000752830.027
mitotic cell cycleGO:00002783260.027
immune responseGO:00069553070.027
segmentationGO:003528240.027
system processGO:00030083490.026
negative regulation of multicellular organismal processGO:00512413170.026
negative regulation of catalytic activityGO:00430863350.026
vesicle mediated transportGO:00161923710.026
nucleoside triphosphate metabolic processGO:00091414220.026
regulation of protein kinase activityGO:00458592890.026
actin filament based processGO:00300292240.026
central nervous system developmentGO:00074171230.026
ribonucleoside triphosphate metabolic processGO:00091994120.026
positive regulation of hydrolase activityGO:00513453310.025
heart developmentGO:0007507950.025
regenerationGO:003109940.025
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.025
Human Yeast
purine ribonucleoside triphosphate metabolic processGO:00092054110.025
positive regulation of transportGO:00510503360.025
cellular lipid metabolic processGO:00442553030.025
biological adhesionGO:00226103310.024
single organism membrane organizationGO:00448022680.024
response to oxygen containing compoundGO:19017003690.024
purine nucleotide catabolic processGO:00061954050.024
response to abiotic stimulusGO:00096283360.024
muscle structure developmentGO:0061061980.024
negative regulation of phosphate metabolic processGO:00459362670.024
regulation of protein localizationGO:00328802960.024
hindbrain developmentGO:003090230.023
negative regulation of developmental processGO:00510932470.023
transmembrane transportGO:00550853990.023
adult locomotory behaviorGO:000834410.023
positive regulation of cellular catabolic processGO:00313312840.023
positive regulation of catabolic processGO:00098963100.023
cellular response to dna damage stimulusGO:00069743790.023
mitotic cell cycle processGO:19030472860.023
positive regulation of cellular component organizationGO:00511303760.023
positive regulation of protein phosphorylationGO:00019343130.023
positive regulation of phosphorylationGO:00423273940.023
nucleoside phosphate catabolic processGO:19012924120.022
regulation of cellular component biogenesisGO:00440872810.022
defense responseGO:00069523150.022
gtp metabolic processGO:00460392390.022
membrane organizationGO:00610242920.022
guanosine containing compound catabolic processGO:19010692390.022
regulation of establishment of protein localizationGO:00702012420.022
memoryGO:000761330.022
brain developmentGO:0007420970.022
gtp catabolic processGO:00061842370.022
guanosine containing compound metabolic processGO:19010682440.022
mapk cascadeGO:00001652880.022
regulation of cellular component movementGO:00512703340.022
chromatin organizationGO:00063253510.022
organ formationGO:004864530.022
positive regulation of cell proliferationGO:00082843010.022
anterior posterior axis specificationGO:000994820.022
regulation of proteolysisGO:00301622930.021
rho protein signal transductionGO:0007266260.021
regulation of protein transportGO:00512232130.021
ras protein signal transductionGO:0007265730.021
cation transportGO:00068123310.021
chemical homeostasisGO:00488783060.021
signal transduction by phosphorylationGO:00230142970.021
negative regulation of phosphorus metabolic processGO:00105632670.021
negative regulation of programmed cell deathGO:00430693210.020
head developmentGO:00603221080.020
regulation of mapk cascadeGO:00434082620.020
cell morphogenesisGO:00009022960.020
purine ribonucleoside triphosphate catabolic processGO:00092073910.020
regulation of purine nucleotide metabolic processGO:19005422640.020
blastoderm segmentationGO:000735020.020
negative regulation of cellular component organizationGO:00511292350.020
regulation of cell migrationGO:00303342890.020
oocyte developmentGO:004859910.020
regulation of cell cycle processGO:00105642660.020
protein catabolic processGO:00301633250.020
positive regulation of nucleotide metabolic processGO:00459812300.020
proteolysis involved in cellular protein catabolic processGO:00516032440.020
regulation of kinase activityGO:00435493140.020
covalent chromatin modificationGO:00165692540.020
protein modification by small protein conjugationGO:00324463420.020
cellular component morphogenesisGO:00329893140.020
anatomical structure formation involved in morphogenesisGO:00486462840.020
Mouse
carbohydrate metabolic processGO:00059752070.020
regulation of locomotionGO:00400123290.020
midbrain developmentGO:0030901450.019
cellular protein catabolic processGO:00442572610.019
negative regulation of apoptotic processGO:00430663160.019
regulation of cellular response to stressGO:00801352440.019
secretionGO:00469032540.019
oocyte differentiationGO:000999420.019
dephosphorylationGO:00163112090.019
positive regulation of immune system processGO:00026842830.019
secretion by cellGO:00329402260.019
apoptotic signaling pathwayGO:00971902680.019
metal ion transportGO:00300012720.019
negative regulation of cell deathGO:00605483450.019
positive regulation of programmed cell deathGO:00430682490.019
innate immune responseGO:00450871780.019
negative regulation of cellular amino acid metabolic processGO:004576320.019
morphogenesis of embryonic epitheliumGO:001633140.019
negative regulation of cellular amine metabolic processGO:003323930.019
compound eye developmentGO:004874910.019
regulation of nucleotide metabolic processGO:00061402690.018
response to cytokineGO:00340972320.018
histone modificationGO:00165702510.018
cell fate determinationGO:000170930.018
spermatid differentiationGO:004851540.018
organelle assemblyGO:00709251760.018
organonitrogen compound biosynthetic processGO:19015662000.018
protein ubiquitinationGO:00165673140.018
specification of organ identityGO:001009230.018
nitrogen compound transportGO:00717051910.018
Yeast
protein maturationGO:00516042330.018
regulation of secretionGO:00510461940.018
skeletal muscle fiber developmentGO:0048741120.018
cellular response to endogenous stimulusGO:00714953360.018
embryo developmentGO:00097901230.018
Zebrafish
regulation of nucleotide catabolic processGO:00308112050.018
positive regulation of purine nucleotide metabolic processGO:19005442270.018
neuroblast proliferationGO:000740540.018
protein processingGO:00164852260.018
neurotransmitter secretionGO:000726940.018
negative regulation of cell proliferationGO:00082852280.018
growthGO:00400072020.018
regulation of response to external stimulusGO:00321012220.018
maintenance of locationGO:00512351120.018
negative regulation of phosphorylationGO:00423261740.018
nerve developmentGO:002167540.018
regulation of intracellular transportGO:00323861950.018
regulation of purine nucleotide catabolic processGO:00331212050.017
cation transmembrane transportGO:00986552380.017
cellular macromolecular complex assemblyGO:00346223240.017
lipid biosynthetic processGO:00086101770.017
cell projection organizationGO:00300302520.017
muscle tissue developmentGO:0060537620.017
spermatid developmentGO:000728640.017
motor neuron axon guidanceGO:000804520.017
regulation of secretion by cellGO:19035301770.017
rhythmic behaviorGO:000762220.017
embryonic epithelial tube formationGO:000183840.017
cellular response to oxygen containing compoundGO:19017012760.017
positive regulation of cell deathGO:00109422630.017
positive regulation of nucleoside metabolic processGO:00459791860.017
regulation of mitotic cell cycleGO:00073461890.017
regulation of cell developmentGO:00602841610.017
small molecule biosynthetic processGO:00442831570.017
ion homeostasisGO:00508012300.017
tripartite regional subdivisionGO:000735120.017
regulation of synaptic plasticityGO:004816730.017
positive regulation of organelle organizationGO:00106381950.017
regulation of nucleoside metabolic processGO:00091182090.017
microtubule based processGO:00070172100.017
regulation of anatomical structure morphogenesisGO:00226032860.016
positive regulation of developmental processGO:00510943140.016
reactive oxygen species biosynthetic processGO:190340940.016
regulation of growthGO:00400081650.016
release of cytoplasmic sequestered nf kappabGO:000858840.016
ion transmembrane transportGO:00342203380.016
carbohydrate derivative biosynthetic processGO:19011372070.016
negative regulation of intracellular signal transductionGO:19025321830.016
negative regulation of cell differentiationGO:00455961710.016
inorganic ion transmembrane transportGO:00986602310.016
response to other organismGO:00517072610.016
anterior posterior axis specification embryoGO:000859520.016
regulation of cell motilityGO:20001452990.016
negative regulation of protein modification processGO:00314002000.016
regulation of protein serine threonine kinase activityGO:00719001790.016
oxidation reduction processGO:00551143960.016
modification dependent macromolecule catabolic processGO:00436322120.016
mitotic cell cycle phase transitionGO:00447721620.016
photoreceptor cell differentiationGO:004653020.016
single organism carbohydrate metabolic processGO:00447231930.016
circadian behaviorGO:004851220.016
spinal cord developmentGO:002151040.016
regulation of cytokine productionGO:00018172320.016
positive regulation of apoptotic processGO:00430652460.016
inner ear morphogenesisGO:004247240.016
positive regulation of cell differentiationGO:00455972110.016
positive regulation of mapk cascadeGO:00434101900.016
muscle cell differentiationGO:0042692630.016
enzyme linked receptor protein signaling pathwayGO:00071673030.016
metencephalon developmentGO:002203720.016
cardiac muscle cell contractionGO:008600340.015
endomembrane system organizationGO:00102561960.015
positive regulation of transferase activityGO:00513472270.015
cell growthGO:00160491600.015
reactive nitrogen species metabolic processGO:200105730.015
negative regulation of cell cycleGO:00457861930.015
positive regulation of kinase activityGO:00336742040.015
cell cycle phase transitionGO:00447701730.015
organophosphate biosynthetic processGO:00904071630.015
proteasomal protein catabolic processGO:00104981760.015
associative learningGO:000830610.015
tissue regenerationGO:004224630.015
modification dependent protein catabolic processGO:00199412090.015
posttranscriptional regulation of gene expressionGO:00106082130.015
ubiquitin dependent protein catabolic processGO:00065112060.015
limbic system developmentGO:002176130.015
positive regulation of purine nucleotide catabolic processGO:00331231850.015
negative regulation of hydrolase activityGO:00513461820.015
cerebellum developmentGO:002154920.015
chromatin modificationGO:00165682980.015
monocarboxylic acid metabolic processGO:00327871850.015
negative regulation of protein phosphorylationGO:00019331400.015
limb morphogenesisGO:0035108160.015
positive regulation of synaptic transmissionGO:005080640.015
regulation of multi organism processGO:00439001570.015
regulation of small gtpase mediated signal transductionGO:00510561560.015
neurological system processGO:00508771630.014
reactive oxygen species metabolic processGO:0072593750.014
positive regulation of protein transportGO:00512221350.014
muscle organ developmentGO:0007517560.014
cellular protein complex assemblyGO:00436231880.014
inorganic cation transmembrane transportGO:00986621940.014
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.014
interspecies interaction between organismsGO:00444191560.014
positive regulation of cellular component biogenesisGO:00440891580.014
dna repairGO:00062811980.014
positive regulation of protein kinase activityGO:00458601900.014
somatic muscle developmentGO:000752510.014
hematopoietic or lymphoid organ developmentGO:00485341860.014
Mouse
response to fungusGO:000962040.014
multi organism cellular processGO:00447641560.014
cell projection assemblyGO:00300311260.014
symbiosis encompassing mutualism through parasitismGO:00444031560.014
regulation of protein catabolic processGO:00421761550.014
cellular response to cytokine stimulusGO:00713451810.014
cation homeostasisGO:00550801890.014
mitochondrion organizationGO:00070051560.014
protein localization to membraneGO:00726571600.014
regulation of immune responseGO:00507762010.014
regulation of neural precursor cell proliferationGO:200017740.014
microtubule cytoskeleton organizationGO:00002261760.014
syncytium formation by plasma membrane fusionGO:000076820.014
thymus developmentGO:004853830.014
regulation of ras protein signal transductionGO:00465781550.014
morphogenesis of a polarized epitheliumGO:000173830.014
appendage developmentGO:0048736230.014
response to radiationGO:00093141510.013
regulation of neurotransmitter secretionGO:004692830.013
organic hydroxy compound metabolic processGO:19016151470.013
regulation of reactive oxygen species biosynthetic processGO:190342630.013
rna interferenceGO:001624640.013
cell activationGO:00017752130.013
Mouse
positive regulation of gtp catabolic processGO:00331261660.013
peptidyl lysine modificationGO:00182051440.013
cytokine productionGO:00018162470.013
stem cell divisionGO:001714520.013
regulation of cytoplasmic transportGO:19036491490.013
visual behaviorGO:000763220.013
rna processingGO:00063962550.013
purine ribonucleoside monophosphate metabolic processGO:00091671860.013
actin cytoskeleton organizationGO:00300362070.013
regulation of protein maturationGO:19033171500.013
nucleoside monophosphate metabolic processGO:00091231910.013
response to axon injuryGO:004867810.013
cell divisionGO:00513011680.013
positive regulation of gtpase activityGO:00435471660.013
regulation of cytoskeleton organizationGO:00514931770.013
positive regulation of nucleotide catabolic processGO:00308131850.013
protein import into nucleus translocationGO:0000060220.013
cranial nerve developmentGO:002154540.013
regulation of endopeptidase activityGO:00525481700.013
anion transportGO:00068201610.013
single organism cell adhesionGO:00986021790.013
response to biotic stimulusGO:00096072760.013
cellular homeostasisGO:00197251960.013
negative regulation of transportGO:00510511760.013
Yeast
alcohol metabolic processGO:00060661140.013
embryonic appendage morphogenesisGO:003511390.013
negative regulation of transferase activityGO:00513481240.013
matingGO:000761810.013
cell projection morphogenesisGO:00488581290.013
regulation of cell growthGO:00015581350.013
viral life cycleGO:00190581320.013
i kappab kinase nf kappab signalingGO:00072491660.013
sex determinationGO:000753030.013
atp metabolic processGO:00460341760.013
response to organic cyclic compoundGO:00140702040.013
epithelium developmentGO:00604292270.013
salivary gland morphogenesisGO:000743540.013
actin mediated cell contractionGO:0070252120.013
response to growth factorGO:00708482050.013
pattern specification processGO:0007389430.013
canonical wnt signaling pathwayGO:00600701160.012
heart formationGO:006091420.012
regulation of meiotic cell cycleGO:005144540.012
regulation of gtpase activityGO:00430871800.012
epithelial cell differentiationGO:00308551410.012
protein oligomerizationGO:00512591730.012
glial cell migrationGO:000834740.012
regulation of dna metabolic processGO:00510521530.012
long term memoryGO:000761620.012
regulation of i kappab kinase nf kappab signalingGO:00431221620.012
regulation of protein processingGO:00706131500.012
glycoprotein metabolic processGO:00091001100.012
neural tube formationGO:000184130.012
cellular chemical homeostasisGO:00550821800.012
somatic stem cell maintenanceGO:003501940.012
cilium organizationGO:0044782680.012
sequestering of metal ionGO:0051238240.012
striated muscle tissue developmentGO:0014706590.012
positive regulation of cytokine productionGO:00018191670.012
appendage morphogenesisGO:0035107160.012
purine nucleoside monophosphate metabolic processGO:00091261860.012
cell part morphogenesisGO:00329901370.012
peptidyl tyrosine modificationGO:00182121700.012
regulation of hormone levelsGO:00108171250.012
regulation of cell adhesionGO:00301551660.012
regulation of ras gtpase activityGO:00323181280.012
negative regulation of protein maturationGO:19033181420.012
neural crest cell developmentGO:001403230.012
ribonucleoside monophosphate metabolic processGO:00091611870.012
carboxylic acid biosynthetic processGO:0046394970.012
t cell differentiation in thymusGO:003307740.012
organic acid biosynthetic processGO:0016053970.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
viral processGO:00160321460.012
myoblast fusionGO:000752010.012
lens development in camera type eyeGO:000208820.012
negative regulation of protein processingGO:00109551420.012
actin filament based movementGO:0030048170.012
macromolecule methylationGO:0043414970.012
peptidyl tyrosine phosphorylationGO:00181081700.012
sensory perception of painGO:001923340.012
positive regulation of immune responseGO:00507781590.012
leukocyte activationGO:00453211640.012
Mouse
cellular response to growth factor stimulusGO:00713631970.012
positive regulation of locomotionGO:00400171860.012
establishment of protein localization to membraneGO:00901501210.012
regulation of reactive oxygen species metabolic processGO:2000377410.012
forelimb morphogenesisGO:003513640.012
tube closureGO:006060630.012
regulation of apoptotic signaling pathwayGO:20012331750.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.012
regulation of cell fate commitmentGO:001045370.012
regulation of vesicle mediated transportGO:00606271300.012
response to external biotic stimulusGO:00432072610.012
cellular cation homeostasisGO:00300031630.012
positive regulation of secretionGO:00510471160.012
regulation of intracellular protein transportGO:00331571230.012
response to nitrogen compoundGO:19016981840.012
striated muscle contractionGO:0006941520.012
positive regulation of cell motilityGO:20001471770.012
establishment of planar polarityGO:000173630.012
positive regulation of cellular component movementGO:00512721810.011
cilium morphogenesisGO:0060271750.011
regulation of wnt signaling pathwayGO:00301111230.011
primary neural tube formationGO:001402030.011
negative regulation of cell migrationGO:00303361020.011
mesodermal cell fate commitmentGO:000171020.011
negative regulation of proteolysisGO:00458611320.011
methylationGO:00322591060.011
divalent metal ion transportGO:00708381520.011
somitogenesisGO:000175620.011
response to lipidGO:00339932060.011
somatic stem cell divisionGO:004810310.011
negative regulation of kinase activityGO:00336731060.011
regulation of cell divisionGO:00513021160.011
regulation of defense responseGO:00313471540.011
endocytosisGO:00068971590.011
prostate gland developmentGO:003085030.011
metal ion homeostasisGO:00550651690.011
mrna metabolic processGO:00160711750.011
meiosis iGO:000712740.011
fatty acid metabolic processGO:00066311150.011
establishment or maintenance of bipolar cell polarityGO:006124520.011
post embryonic organ developmentGO:004856910.011
immune effector processGO:00022521590.011
regulation of peptidase activityGO:00525471800.011
developmental programmed cell deathGO:001062330.011
endosomal transportGO:00161971290.011
defense response to fungusGO:005083240.011
regulation of transcription from rna polymerase ii promoter mitoticGO:004602110.011
positive regulation of cell cycleGO:00457871400.011
forebrain generation of neuronsGO:002187230.011
response to virusGO:00096151260.011
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.011
negative regulation of locomotionGO:00400131180.011
regulation of cysteine type endopeptidase activityGO:20001161270.011
regulation of bindingGO:00510981110.011
sequestering of calcium ionGO:0051208170.011
establishment of tissue polarityGO:000716430.011
embryonic forelimb morphogenesisGO:003511540.011
divalent inorganic cation transportGO:00725111580.011
positive regulation of ras gtpase activityGO:00323201170.011
negative regulation of cell cycle processGO:00109481210.011
muscle system processGO:0003012810.011
regulation of protein complex assemblyGO:00432541470.011
neural tube closureGO:000184330.011
epidermis morphogenesisGO:004873030.011
sulfur compound metabolic processGO:00067901010.011
striated muscle cell differentiationGO:0051146430.011
cell substrate adhesionGO:00315891320.011
lung alveolus developmentGO:004828640.011
regionalizationGO:0003002290.011
positive regulation of proteolysisGO:00458621420.011
regulation of cell morphogenesisGO:00226041530.011
establishment or maintenance of apical basal cell polarityGO:003508820.011
regulation of homeostatic processGO:00328441210.011
sleepGO:003043120.011
cellular metal ion homeostasisGO:00068751460.011
taxisGO:00423301570.011
ossificationGO:00015031210.011
positive regulation of neural precursor cell proliferationGO:200017920.011
cardiac muscle contractionGO:0060048340.011

PKNOX1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.027
inherited metabolic disorderDOID:6552420.023
sensory system diseaseDOID:00501552030.023
nervous system diseaseDOID:8634310.023
musculoskeletal system diseaseDOID:172230.022
central nervous system diseaseDOID:3311860.020
cancerDOID:1621670.019
disease of cellular proliferationDOID:145661740.019
eye diseaseDOID:56141490.019
eye and adnexa diseaseDOID:14921500.019
organ system cancerDOID:00506861640.017
connective tissue diseaseDOID:651090.015
immune system diseaseDOID:29141550.015
retinal diseaseDOID:56791180.014
bone diseaseDOID:0080001880.014
neurodegenerative diseaseDOID:12891020.013
myopathyDOID:4231040.013
muscle tissue diseaseDOID:661130.013
muscular diseaseDOID:00800001140.013
cardiovascular system diseaseDOID:12871060.012
retinal degenerationDOID:8466890.011
brain diseaseDOID:936730.011
disease of mental healthDOID:150700.011