Homo sapiens

11 known processes

KRT4

keratin 4

(Aliases: K4,CK-4,CYK4,FLJ31692,CK4)

KRT4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
keratinizationGO:003142420.885
Human
hair follicle morphogenesisGO:003106920.637
Human
epidermis morphogenesisGO:004873030.527
Human
keratinocyte differentiationGO:0030216360.359
Human
golgi to plasma membrane cftr protein transportGO:004300010.228
hair cycleGO:0042633280.191
Human
intermediate filament based processGO:0045103170.180
Human
epithelium developmentGO:00604292270.179
Human
epidermal cell differentiationGO:0009913450.177
Human
skin developmentGO:0043588760.156
Human
epidermis developmentGO:0008544590.145
Human
epithelial cell differentiationGO:00308551410.100
Human
intermediate filament organizationGO:0045109100.093
Human
negative regulation of cell deathGO:00605483450.092
system processGO:00030083490.083
immune responseGO:00069553070.078
Human
lipid metabolic processGO:00066293810.077
intermediate filament cytoskeleton organizationGO:0045104170.062
Human
multicellular organismal homeostasisGO:0048871670.061
Human
complement activationGO:0006956190.055
Human
post embryonic developmentGO:000979120.052
retina homeostasisGO:0001895420.052
Human
negative regulation of programmed cell deathGO:00430693210.047
negative regulation of apoptotic processGO:00430663160.046
multicellular organismal agingGO:001025930.045
neurological system processGO:00508771630.045
testosterone biosynthetic processGO:006137020.045
tissue regenerationGO:004224630.044
Zebrafish
defense responseGO:00069523150.043
Human
cellular lipid metabolic processGO:00442553030.042
tissue migrationGO:00901301190.041
Human
humoral immune responseGO:0006959490.041
Human
regenerationGO:003109940.041
Zebrafish
organ morphogenesisGO:00098871470.041
Human
regulation of cellular component movementGO:00512703340.041
small molecule biosynthetic processGO:00442831570.041
determination of adult lifespanGO:000834020.040
epoxygenase p450 pathwayGO:001937330.040
negative regulation of catalytic activityGO:00430863350.039
cellular ketone metabolic processGO:0042180800.039
purine containing compound catabolic processGO:00725234110.038
response to lipidGO:00339932060.037
protein processingGO:00164852260.037
tissue morphogenesisGO:0048729960.037
Human
cellular component morphogenesisGO:00329893140.036
actin filament based processGO:00300292240.036
organic hydroxy compound metabolic processGO:19016151470.036
protein maturationGO:00516042330.035
response to other organismGO:00517072610.035
hormone metabolic processGO:0042445610.035
anatomical structure formation involved in morphogenesisGO:00486462840.035
amine metabolic processGO:0009308440.034
oxidation reduction processGO:00551143960.034
positive regulation of immune system processGO:00026842830.033
Human
single organism membrane organizationGO:00448022680.033
fatty acid metabolic processGO:00066311150.033
regulation of locomotionGO:00400123290.033
memoryGO:000761330.033
positive regulation of cell proliferationGO:00082843010.032
fatty acid omega oxidationGO:001043020.032
cellular amine metabolic processGO:0044106410.031
innate immune responseGO:00450871780.031
Human
purine ribonucleoside metabolic processGO:00461284370.030
keratinocyte migrationGO:005154660.030
Human
cellular amino acid metabolic processGO:00065201160.030
segmentationGO:003528240.029
epithelial cell migrationGO:00106311190.029
Human
growthGO:00400072020.029
Zebrafish
negative regulation of peptidase activityGO:0010466910.029
single organism cellular localizationGO:19025803320.029
cytoplasmic transportGO:00164823790.028
keratinocyte activationGO:003298010.028
Human
epithelial cell proliferationGO:00506731280.028
Human
negative regulation of cellular protein metabolic processGO:00322693530.027
regulation of proteolysisGO:00301622930.027
response to oxygen containing compoundGO:19017003690.027
anatomical structure homeostasisGO:00602491000.027
Human
protein localization to membraneGO:00726571600.027
membrane organizationGO:00610242920.027
intracellular protein transportGO:00068862700.026
positive regulation of cellular amino acid metabolic processGO:004576430.026
cellular response to cytokine stimulusGO:00713451810.026
purine nucleotide catabolic processGO:00061954050.026
purine ribonucleoside triphosphate catabolic processGO:00092073910.026
ribonucleoside catabolic processGO:00424544060.025
nucleoside catabolic processGO:00091644080.025
chemical homeostasisGO:00488783060.024
renal water homeostasisGO:000309140.024
regulation of cellular amino acid metabolic processGO:000652160.024
organelle assemblyGO:00709251760.024
negative regulation of hydrolase activityGO:00513461820.024
tongue developmentGO:004358610.024
locomotory behaviorGO:000762610.024
negative regulation of protein metabolic processGO:00512483910.024
vesicle mediated transportGO:00161923710.024
atp metabolic processGO:00460341760.024
actin filament based movementGO:0030048170.023
actin mediated cell contractionGO:0070252120.023
cation transmembrane transportGO:00986552380.023
regulation of protein maturationGO:19033171500.023
nucleoside phosphate catabolic processGO:19012924120.023
response to biotic stimulusGO:00096072760.023
immune effector processGO:00022521590.023
Human
long chain fatty acid metabolic processGO:0001676300.023
sex determinationGO:000753030.023
regulation of protein processingGO:00706131500.023
negative regulation of interferon gamma secretionGO:190271410.022
small gtpase mediated signal transductionGO:0007264780.022
epithelium migrationGO:00901321190.022
Human
purine ribonucleotide catabolic processGO:00091544040.022
protein activation cascadeGO:0072376220.022
Human
purine ribonucleoside catabolic processGO:00461303980.022
positive regulation of immune responseGO:00507781590.021
Human
organophosphate catabolic processGO:00464344300.021
mapk cascadeGO:00001652880.021
lipid biosynthetic processGO:00086101770.021
purine ribonucleoside triphosphate metabolic processGO:00092054110.021
cellular modified amino acid metabolic processGO:0006575640.021
defense response to fungusGO:005083240.021
tissue homeostasisGO:0001894630.021
Human
morphogenesis of an epitheliumGO:0002009600.021
Human
nucleoside triphosphate metabolic processGO:00091414220.021
ribonucleoside triphosphate metabolic processGO:00091994120.021
ion transmembrane transportGO:00342203380.020
blastoderm segmentationGO:000735020.020
cell activationGO:00017752130.020
Human
alcohol metabolic processGO:00060661140.020
nucleotide catabolic processGO:00091664080.020
glycosyl compound catabolic processGO:19016584130.020
activation of immune responseGO:00022531140.020
Human
ras protein signal transductionGO:0007265730.020
regulation of peptidase activityGO:00525471800.020
regulation of cell cycle processGO:00105642660.020
salivary gland morphogenesisGO:000743540.019
reactive oxygen species biosynthetic processGO:190340940.019
biological adhesionGO:00226103310.019
cellular macromolecule catabolic processGO:00442653800.019
cellular response to dna damage stimulusGO:00069743790.019
negative regulation of cellular component movementGO:00512711060.019
purine nucleoside triphosphate metabolic processGO:00091444120.019
cloacal septationGO:006019710.019
regulation of cellular ketone metabolic processGO:0010565500.019
regulation of cell migrationGO:00303342890.019
maintenance of locationGO:00512351120.019
regulation of endopeptidase activityGO:00525481700.019
establishment of protein localization to membraneGO:00901501210.018
cellular response to endogenous stimulusGO:00714953360.018
response to organic cyclic compoundGO:00140702040.018
reactive nitrogen species metabolic processGO:200105730.018
muscle cell differentiationGO:0042692630.018
inorganic ion transmembrane transportGO:00986602310.018
regulation of immune responseGO:00507762010.018
Human
response to external biotic stimulusGO:00432072610.018
striated muscle cell differentiationGO:0051146430.018
anion transportGO:00068201610.018
ribonucleoside triphosphate catabolic processGO:00092033910.018
response to abiotic stimulusGO:00096283360.018
female gamete generationGO:000729220.018
negative regulation of proteolysisGO:00458611320.017
muscle structure developmentGO:0061061980.017
agingGO:0007568660.017
Human
actin cytoskeleton organizationGO:00300362070.017
regulation of cell motilityGO:20001452990.017
regulation of cell cycleGO:00517263930.017
purine nucleoside triphosphate catabolic processGO:00091463920.017
positive regulation of cellular catabolic processGO:00313312840.017
positive regulation of hydrolase activityGO:00513453310.017
molting cycleGO:0042303280.017
Human
anterior posterior axis specificationGO:000994820.017
reactive oxygen species metabolic processGO:0072593750.017
neuromuscular junction developmentGO:000752830.017
negative regulation of protein maturationGO:19033181420.017
ameboidal type cell migrationGO:00016671350.017
Human
cellular component assembly involved in morphogenesisGO:0010927730.017
somatic stem cell maintenanceGO:003501940.016
response to radiationGO:00093141510.016
endomembrane system organizationGO:00102561960.016
striated muscle contractionGO:0006941520.016
transmembrane transportGO:00550853990.016
embryonic forelimb morphogenesisGO:003511540.016
purine ribonucleoside monophosphate metabolic processGO:00091671860.016
adult locomotory behaviorGO:000834410.016
mitotic cell cycleGO:00002783260.016
linoleic acid metabolic processGO:004365140.016
negative regulation of developmental processGO:00510932470.016
spermatid differentiationGO:004851540.016
carboxylic acid biosynthetic processGO:0046394970.016
cellular macromolecular complex assemblyGO:00346223240.016
oocyte developmentGO:004859910.016
dephosphorylationGO:00163112090.016
negative regulation of endopeptidase activityGO:0010951840.016
response to fungusGO:000962040.016
muscle cell developmentGO:0055001290.016
golgi vesicle transportGO:0048193800.016
regulation of cellular amine metabolic processGO:0033238110.016
cellular response to oxygen containing compoundGO:19017012760.016
regulation of nucleotide catabolic processGO:00308112050.016
hair cycle processGO:0022405120.016
Human
nucleoside triphosphate catabolic processGO:00091433940.016
purine nucleoside catabolic processGO:00061523980.016
negative regulation of locomotionGO:00400131180.016
prostate gland developmentGO:003085030.016
ribonucleotide catabolic processGO:00092614050.015
positive regulation of phosphorylationGO:00423273940.015
nucleoside monophosphate metabolic processGO:00091231910.015
positive regulation of catabolic processGO:00098963100.015
positive regulation of cellular amine metabolic processGO:003324070.015
protein oligomerizationGO:00512591730.015
positive regulation of cellular component organizationGO:00511303760.015
rhythmic behaviorGO:000762220.015
cardiovascular system developmentGO:00723582620.015
cell morphogenesisGO:00009022960.015
nucleoside monophosphate catabolic processGO:00091251590.015
histone modificationGO:00165702510.015
organic acid biosynthetic processGO:0016053970.015
regulation of anatomical structure morphogenesisGO:00226032860.015
regulation of mitotic cell cycleGO:00073461890.015
nervous system developmentGO:00073992930.015
regulation of nucleoside metabolic processGO:00091182090.015
negative regulation of protein processingGO:00109551420.015
protein localization to plasma membraneGO:0072659930.015
negative regulation of cellular amine metabolic processGO:003323930.015
isoprenoid metabolic processGO:0006720390.015
negative regulation of cell proliferationGO:00082852280.015
positive regulation of nucleotide catabolic processGO:00308131850.015
monocarboxylic acid metabolic processGO:00327871850.015
oogenesisGO:004847720.015
regulation of reactive oxygen species biosynthetic processGO:190342630.014
terpenoid metabolic processGO:0006721270.014
regulation of reactive oxygen species metabolic processGO:2000377410.014
ribonucleoside monophosphate metabolic processGO:00091611870.014
compound eye developmentGO:004874910.014
chromatin organizationGO:00063253510.014
circadian behaviorGO:004851220.014
cell adhesionGO:00071553250.014
protein catabolic processGO:00301633250.014
mitotic cell cycle processGO:19030472860.014
oxidative stress induced premature senescenceGO:009040330.014
vitamin k catabolic processGO:004237720.014
coenzyme metabolic processGO:0006732650.014
establishment of protein localization to plasma membraneGO:0090002680.014
regulation of cell differentiationGO:00455953930.014
negative regulation of multicellular organismal processGO:00512413170.014
negative regulation of cellular amino acid metabolic processGO:004576320.014
response to growth factorGO:00708482050.014
chromatin modificationGO:00165682980.014
cardiac muscle cell contractionGO:008600340.014
negative regulation of cellular component organizationGO:00511292350.014
protein acylationGO:00435431380.014
protein localization to organelleGO:00333652800.014
cell growthGO:00160491600.014
proteolysis involved in cellular protein catabolic processGO:00516032440.014
post embryonic organ developmentGO:004856910.014
regulation of cytoskeleton organizationGO:00514931770.014
positive regulation of nucleoside metabolic processGO:00459791860.013
regulation of mapk cascadeGO:00434082620.013
cellular protein catabolic processGO:00442572610.013
regulation of male gonad developmentGO:200001840.013
positive regulation of dermatome developmentGO:006118430.013
protein modification by small protein conjugationGO:00324463420.013
carbohydrate derivative biosynthetic processGO:19011372070.013
sensory perception of painGO:001923340.013
posttranscriptional regulation of gene expressionGO:00106082130.013
spermatid developmentGO:000728640.013
actomyosin structure organizationGO:0031032590.013
response to estrogenGO:0043627470.013
ribonucleoside monophosphate catabolic processGO:00091581580.013
positive regulation of organelle organizationGO:00106381950.013
positive regulation of transportGO:00510503360.013
regulation of cell adhesionGO:00301551660.013
water homeostasisGO:0030104140.013
peripheral nervous system developmentGO:000742220.013
canonical wnt signaling pathway involved in osteoblast differentiationGO:004433920.013
cellular protein complex assemblyGO:00436231880.013
regulation of transferase activityGO:00513383550.013
hindlimb morphogenesisGO:003513720.013
defense response to other organismGO:00985421290.013
signal transduction by phosphorylationGO:00230142970.012
regulation of i kappab kinase nf kappab signalingGO:00431221620.012
regulation of secretionGO:00510461940.012
morphogenesis of embryonic epitheliumGO:001633140.012
cofactor metabolic processGO:0051186870.012
modification dependent protein catabolic processGO:00199412090.012
negative regulation of cell migrationGO:00303361020.012
regulation of protein catabolic processGO:00421761550.012
forebrain regionalizationGO:002187130.012
embryonic epithelial tube formationGO:000183840.012
oocyte differentiationGO:000999420.012
muscle system processGO:0003012810.012
response to woundingGO:00096111680.012
Zebrafish
pulmonary valve formationGO:000319310.012
negative regulation of cell motilityGO:20001461040.012
cellular hormone metabolic processGO:0034754410.012
covalent chromatin modificationGO:00165692540.012
nitrogen compound transportGO:00717051910.012
mitochondrion organizationGO:00070051560.012
negative regulation of androgen biosynthetic processGO:200018010.012
regulation of meiotic cell cycleGO:005144540.012
plasma membrane organizationGO:00070091150.012
positive regulation of kinase activityGO:00336742040.012
positive regulation of purine nucleotide catabolic processGO:00331231850.012
i kappab kinase nf kappab signalingGO:00072491660.012
keratinocyte proliferationGO:0043616170.012
Human
microtubule based processGO:00070172100.012
phylloquinone metabolic processGO:004237420.012
nucleocytoplasmic transportGO:00069131760.012
regulation of response to external stimulusGO:00321012220.012
positive regulation of insulin like growth factor receptor signaling pathwayGO:004356840.012
negative regulation of transportGO:00510511760.012
anterior posterior axis specification embryoGO:000859520.012
purine nucleoside monophosphate metabolic processGO:00091261860.012
positive regulation of cellular component movementGO:00512721810.012
cell projection organizationGO:00300302520.012
enzyme linked receptor protein signaling pathwayGO:00071673030.012
menaquinone catabolic processGO:004236120.012
regulation of cell cycle phase transitionGO:19019871260.012
regulation of gtpase activityGO:00430871800.012
response to virusGO:00096151260.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
regulation of actin filament based processGO:00329701410.012
modification dependent macromolecule catabolic processGO:00436322120.012
negative regulation of phosphorus metabolic processGO:00105632670.012
tube developmentGO:00352951250.012
response to hormoneGO:00097251750.012
positive regulation of programmed cell deathGO:00430682490.011
tripartite regional subdivisionGO:000735120.011
regulation of sequence specific dna binding transcription factor activityGO:00510902110.011
lipid localizationGO:00108761060.011
circulatory system developmentGO:00723592620.011
guanosine containing compound catabolic processGO:19010692390.011
startle responseGO:000196430.011
vitamin e metabolic processGO:004236010.011
negative regulation of catabolic processGO:00098951040.011
regulation of neural precursor cell proliferationGO:200017740.011
regulation of hormone levelsGO:00108171250.011
ion homeostasisGO:00508012300.011
regulation of ras gtpase activityGO:00323181280.011
negative regulation of mitotic cell cycleGO:00459301020.011
response to cytokineGO:00340972320.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.011
neuroblast proliferationGO:000740540.011
atp catabolic processGO:00062001570.011
fatty acid derivative catabolic processGO:190156920.011
glycerolipid metabolic processGO:00464861070.011
protein targetingGO:00066051870.011
hindbrain developmentGO:003090230.011
isoquinoline alkaloid metabolic processGO:003307610.011
cell cycle checkpointGO:00000751170.011
positive regulation of cell differentiationGO:00455972110.011
leukotriene catabolic processGO:003610020.011
regulation of growthGO:00400081650.011
response to activityGO:001482300.011
regulation of multi organism processGO:00439001570.011
cardiac muscle contractionGO:0060048340.011
interspecies interaction between organismsGO:00444191560.011
blastocyst developmentGO:000182430.011
mesenchymal to epithelial transition involved in metanephros morphogenesisGO:000333740.011
protein modification by small protein removalGO:0070646920.011
purine ribonucleoside monophosphate catabolic processGO:00091691580.011
regulation of apoptotic signaling pathwayGO:20012331750.011
response to axon injuryGO:004867810.011
purine nucleoside monophosphate catabolic processGO:00091281580.011
rna processingGO:00063962550.011
cellular response to transforming growth factor beta stimulusGO:0071560940.011
regulation of body fluid levelsGO:0050878990.011
cell divisionGO:00513011680.011
limbic system developmentGO:002176130.011
response to transforming growth factor betaGO:0071559940.011
monocarboxylic acid biosynthetic processGO:0072330670.011
cellular response to lipidGO:00713961270.011
myosin filament assemblyGO:003103420.011
positive regulation of cell cycle processGO:00900681060.011
positive regulation of cell deathGO:00109422630.011
steroid metabolic processGO:0008202940.011
cell cycle phase transitionGO:00447701730.011
negative regulation of cell cycle phase transitionGO:1901988890.011
ubiquitin dependent protein catabolic processGO:00065112060.011
regulation of purine nucleotide catabolic processGO:00331212050.010
protein ubiquitinationGO:00165673140.010
non canonical wnt signaling pathway via mapk cascadeGO:003803040.010
gtp catabolic processGO:00061842370.010
positive regulation of mapk cascadeGO:00434101900.010
myosin filament organizationGO:003103320.010
vitamin k biosynthetic processGO:004237120.010
positive regulation of transferase activityGO:00513472270.010
somitogenesisGO:000175620.010
regulation of glial cell proliferationGO:006025140.010
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.010
av node cell to bundle of his cell communicationGO:008606740.010
regulation of actin cytoskeleton organizationGO:00329561160.010
inorganic anion transmembrane transportGO:0098661470.010
hepoxilin biosynthetic processGO:005112210.010
anion transmembrane transportGO:0098656760.010
positive regulation of purine nucleotide metabolic processGO:19005442270.010
regulation of mitotic cell cycle phase transitionGO:19019901180.010
regulation of cysteine type endopeptidase activityGO:20001161270.010
response to decreased oxygen levelsGO:0036293960.010
regulation of protein transportGO:00512232130.010
regulation of nucleotide metabolic processGO:00061402690.010
negative regulation of phosphate metabolic processGO:00459362670.010
regulation of cellular response to stressGO:00801352440.010
protein homooligomerizationGO:00512601000.010
rho protein signal transductionGO:0007266260.010
proteasomal protein catabolic processGO:00104981760.010
post golgi vesicle mediated transportGO:0006892360.010

KRT4 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.040
nervous system diseaseDOID:8634310.040
sensory system diseaseDOID:00501552030.040
musculoskeletal system diseaseDOID:172230.028
eye and adnexa diseaseDOID:14921500.026
inherited metabolic disorderDOID:6552420.024
eye diseaseDOID:56141490.023
retinal diseaseDOID:56791180.023
skin diseaseDOID:37330.021
integumentary system diseaseDOID:16430.021
central nervous system diseaseDOID:3311860.019
cancerDOID:1621670.017
disease of cellular proliferationDOID:145661740.017
organ system cancerDOID:00506861640.017
retinal degenerationDOID:8466890.015
connective tissue diseaseDOID:651090.013
bone diseaseDOID:0080001880.013
muscular diseaseDOID:00800001140.011
muscle tissue diseaseDOID:661130.011
auditory system diseaseDOID:2742530.010