Homo sapiens

7 known processes

PLEKHM2

pleckstrin homology domain containing, family M (with RUN domain) member 2

(Aliases: SKIP,RP11-169K16.1,KIAA0842)

PLEKHM2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
inorganic ion transmembrane transportGO:00986602310.063
positive regulation of hydrolase activityGO:00513453310.056
lipid metabolic processGO:00066293810.055
positive regulation of protein phosphorylationGO:00019343130.054
cellular amine metabolic processGO:0044106410.053
cellular ketone metabolic processGO:0042180800.052
determination of adult lifespanGO:000834020.051
regulation of purine nucleotide catabolic processGO:00331212050.050
locomotory behaviorGO:000762610.049
post embryonic developmentGO:000979120.047
purine nucleoside triphosphate metabolic processGO:00091444120.047
cellular macromolecule catabolic processGO:00442653800.047
purine nucleotide catabolic processGO:00061954050.047
positive regulation of cellular amino acid metabolic processGO:004576430.046
nucleotide catabolic processGO:00091664080.046
positive regulation of catabolic processGO:00098963100.046
ras protein signal transductionGO:0007265730.045
single organism cellular localizationGO:19025803320.045
multicellular organismal agingGO:001025930.045
response to oxygen containing compoundGO:19017003690.045
positive regulation of cellular amine metabolic processGO:003324070.043
amine metabolic processGO:0009308440.040
regulation of cellular amino acid metabolic processGO:000652160.038
female gamete generationGO:000729220.038
system processGO:00030083490.037
purine ribonucleoside metabolic processGO:00461284370.037
glycosyl compound catabolic processGO:19016584130.037
regulation of cellular ketone metabolic processGO:0010565500.037
cellular lipid metabolic processGO:00442553030.037
gtp metabolic processGO:00460392390.036
guanosine containing compound catabolic processGO:19010692390.036
regulation of cellular amine metabolic processGO:0033238110.036
nucleoside catabolic processGO:00091644080.035
purine containing compound catabolic processGO:00725234110.035
ribonucleoside triphosphate metabolic processGO:00091994120.034
nucleoside phosphate catabolic processGO:19012924120.034
nucleoside triphosphate catabolic processGO:00091433940.033
positive regulation of gtpase activityGO:00435471660.033
protein catabolic processGO:00301633250.033
gtp catabolic processGO:00061842370.033
negative regulation of cellular component organizationGO:00511292350.033
mitotic cell cycleGO:00002783260.031
negative regulation of cellular protein metabolic processGO:00322693530.031
protein localization to organelleGO:00333652800.031
purine nucleoside catabolic processGO:00061523980.030
positive regulation of nucleotide catabolic processGO:00308131850.030
regulation of kinase activityGO:00435493140.029
rho protein signal transductionGO:0007266260.029
cellular component morphogenesisGO:00329893140.029
regulation of protein localizationGO:00328802960.029
positive regulation of phosphorylationGO:00423273940.029
positive regulation of nucleoside metabolic processGO:00459791860.029
purine ribonucleotide catabolic processGO:00091544040.029
cellular response to oxygen containing compoundGO:19017012760.029
cellular amino acid metabolic processGO:00065201160.029
positive regulation of purine nucleotide catabolic processGO:00331231850.028
regulation of gtpase activityGO:00430871800.028
immune responseGO:00069553070.028
mitotic cell cycle processGO:19030472860.028
regulation of ras gtpase activityGO:00323181280.028
membrane organizationGO:00610242920.028
cellular response to endogenous stimulusGO:00714953360.028
purine ribonucleoside catabolic processGO:00461303980.028
regulation of transferase activityGO:00513383550.027
regulation of protein kinase activityGO:00458592890.027
mapk cascadeGO:00001652880.027
positive regulation of cellular catabolic processGO:00313312840.027
transmembrane transportGO:00550853990.027
negative regulation of catalytic activityGO:00430863350.027
regulation of nucleotide catabolic processGO:00308112050.026
protein autophosphorylationGO:00467771230.026
ribonucleoside catabolic processGO:00424544060.026
positive regulation of purine nucleotide metabolic processGO:19005442270.026
positive regulation of transportGO:00510503360.026
regulation of cell cycleGO:00517263930.026
regulation of gtp catabolic processGO:00331241800.026
guanosine containing compound metabolic processGO:19010682440.026
secretionGO:00469032540.026
inorganic cation transmembrane transportGO:00986621940.025
segmentationGO:003528240.025
nucleoside triphosphate metabolic processGO:00091414220.025
regulation of nucleotide metabolic processGO:00061402690.025
positive regulation of cellular component organizationGO:00511303760.025
small molecule biosynthetic processGO:00442831570.025
purine ribonucleoside triphosphate metabolic processGO:00092054110.025
cation transmembrane transportGO:00986552380.025
regulation of cell differentiationGO:00455953930.024
positive regulation of nucleotide metabolic processGO:00459812300.024
regulation of anatomical structure morphogenesisGO:00226032860.024
ribonucleoside triphosphate catabolic processGO:00092033910.024
protein processingGO:00164852260.024
defense responseGO:00069523150.024
regulation of nucleoside metabolic processGO:00091182090.024
chemical homeostasisGO:00488783060.024
small gtpase mediated signal transductionGO:0007264780.024
activation of protein kinase activityGO:0032147900.023
negative regulation of phosphorus metabolic processGO:00105632670.023
actin cytoskeleton organizationGO:00300362070.023
regulation of cell divisionGO:00513021160.023
maintenance of locationGO:00512351120.023
cell morphogenesisGO:00009022960.023
negative regulation of organelle organizationGO:00106391260.023
organophosphate catabolic processGO:00464344300.022
positive regulation of kinase activityGO:00336742040.022
single organism membrane organizationGO:00448022680.022
regulation of cell cycle processGO:00105642660.022
histone modificationGO:00165702510.022
regulation of establishment of protein localizationGO:00702012420.022
protein localization to membraneGO:00726571600.022
negative regulation of cell deathGO:00605483450.022
regulation of proteolysisGO:00301622930.022
regulation of cellular response to stressGO:00801352440.022
regulation of purine nucleotide metabolic processGO:19005422640.021
cytoplasmic transportGO:00164823790.021
nucleoside monophosphate metabolic processGO:00091231910.021
negative regulation of apoptotic processGO:00430663160.021
glycerolipid metabolic processGO:00464861070.021
purine ribonucleoside triphosphate catabolic processGO:00092073910.021
actin filament based processGO:00300292240.021
signal transduction by phosphorylationGO:00230142970.021
lipid biosynthetic processGO:00086101770.020
protein maturationGO:00516042330.020
cellular protein catabolic processGO:00442572610.020
response to abiotic stimulusGO:00096283360.020
negative regulation of protein processingGO:00109551420.020
regulation of ras protein signal transductionGO:00465781550.020
negative regulation of protein metabolic processGO:00512483910.020
organelle fissionGO:00482851490.019
apoptotic signaling pathwayGO:00971902680.019
positive regulation of transferase activityGO:00513472270.019
oogenesisGO:004847720.019
purine nucleoside triphosphate catabolic processGO:00091463920.019
neuromuscular junction developmentGO:000752830.019
proteolysis involved in cellular protein catabolic processGO:00516032440.019
covalent chromatin modificationGO:00165692540.018
positive regulation of gtp catabolic processGO:00331261660.018
microtubule based processGO:00070172100.018
negative regulation of intracellular signal transductionGO:19025321830.018
regulation of response to external stimulusGO:00321012220.018
innate immune responseGO:00450871780.018
nucleus localizationGO:005164710.018
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.018
modification dependent macromolecule catabolic processGO:00436322120.017
atp metabolic processGO:00460341760.017
proteasomal protein catabolic processGO:00104981760.017
regulation of mapk cascadeGO:00434082620.017
spermatid differentiationGO:004851540.017
spermatid developmentGO:000728640.017
enzyme linked receptor protein signaling pathwayGO:00071673030.017
regulation of secretionGO:00510461940.017
autophagyGO:0006914880.017
ion transmembrane transportGO:00342203380.017
endomembrane system organizationGO:00102561960.016
secretion by cellGO:00329402260.016
response to external biotic stimulusGO:00432072610.016
negative regulation of phosphate metabolic processGO:00459362670.016
positive regulation of digestive system processGO:006045620.016
vesicle mediated transportGO:00161923710.016
single organism carbohydrate metabolic processGO:00447231930.016
positive regulation of protein kinase activityGO:00458601900.016
cell projection organizationGO:00300302520.016
response to other organismGO:00517072610.016
regulation of growthGO:00400081650.016
rhythmic behaviorGO:000762220.016
plasma membrane organizationGO:00070091150.016
negative regulation of phosphorylationGO:00423261740.016
regulation of sequence specific dna binding transcription factor activityGO:00510902110.016
establishment of protein localization to membraneGO:00901501210.015
negative regulation of hydrolase activityGO:00513461820.015
adult locomotory behaviorGO:000834410.015
regulation of immune responseGO:00507762010.015
ubiquitin dependent protein catabolic processGO:00065112060.015
hindbrain developmentGO:003090230.015
purine ribonucleoside monophosphate metabolic processGO:00091671860.015
alcohol metabolic processGO:00060661140.015
cell divisionGO:00513011680.015
sterol transportGO:0015918390.015
purine nucleoside monophosphate metabolic processGO:00091261860.015
regulation of protein processingGO:00706131500.015
release of cytoplasmic sequestered nf kappabGO:000858840.015
negative regulation of protein maturationGO:19033181420.015
positive regulation of immune system processGO:00026842830.015
mitotic nuclear divisionGO:00070671190.015
regulation of cell morphogenesisGO:00226041530.015
regulation of protein maturationGO:19033171500.014
response to organonitrogen compoundGO:00102431560.014
lung alveolus developmentGO:004828640.014
regulation of peptidase activityGO:00525471800.014
neurological system processGO:00508771630.014
response to biotic stimulusGO:00096072760.014
positive regulation of synaptic transmissionGO:005080640.014
protein modification by small protein conjugationGO:00324463420.014
positive regulation of ras gtpase activityGO:00323201170.014
response to fungusGO:000962040.014
cell adhesionGO:00071553250.014
response to nitrogen compoundGO:19016981840.014
nervous system developmentGO:00073992930.014
response to hormoneGO:00097251750.014
syncytium formation by plasma membrane fusionGO:000076820.014
purine ribonucleoside monophosphate catabolic processGO:00091691580.014
carbohydrate derivative biosynthetic processGO:19011372070.014
endosomal transportGO:00161971290.014
cellular response to growth factor stimulusGO:00713631970.014
somitogenesisGO:000175620.014
organophosphate biosynthetic processGO:00904071630.014
metencephalon developmentGO:002203720.013
cell fate determinationGO:000170930.013
associative learningGO:000830610.013
cell growthGO:00160491600.013
regulation of locomotionGO:00400123290.013
regulation of cell motilityGO:20001452990.013
negative regulation of transportGO:00510511760.013
regulation of secretion by cellGO:19035301770.013
cellular response to extracellular stimulusGO:0031668720.013
nitrogen compound transportGO:00717051910.013
microtubule cytoskeleton organizationGO:00002261760.013
activation of immune responseGO:00022531140.013
ribonucleotide catabolic processGO:00092614050.013
regulation of small gtpase mediated signal transductionGO:00510561560.013
nuclear migrationGO:000709710.013
sensory perception of smellGO:000760820.013
growthGO:00400072020.013
regulation of mitotic cell cycleGO:00073461890.013
biological adhesionGO:00226103310.013
ribonucleoside monophosphate catabolic processGO:00091581580.013
dephosphorylationGO:00163112090.012
neurotransmitter secretionGO:000726940.012
peripheral nervous system developmentGO:000742220.012
regulation of protein complex assemblyGO:00432541470.012
positive regulation of cellular component biogenesisGO:00440891580.012
regulation of neural precursor cell proliferationGO:200017740.012
chromatin modificationGO:00165682980.012
regulation of defense responseGO:00313471540.012
response to bacteriumGO:00096171440.012
establishment of nucleus localizationGO:004002310.012
regulation of cytokine productionGO:00018172320.012
cellular homeostasisGO:00197251960.012
intracellular protein transportGO:00068862700.012
response to molecule of bacterial originGO:0002237820.012
protein ubiquitinationGO:00165673140.012
fatty acid metabolic processGO:00066311150.012
positive regulation of innate immune responseGO:0045089790.012
negative regulation of proteolysisGO:00458611320.012
lipid transportGO:0006869900.012
positive regulation of organelle organizationGO:00106381950.012
regulation of rab gtpase activityGO:0032313390.012
intracellular mrna localizationGO:000829810.012
regulation of cellular component biogenesisGO:00440872810.012
nucleoside monophosphate catabolic processGO:00091251590.012
regulation of homeostatic processGO:00328441210.012
memoryGO:000761330.012
regulation of cell growthGO:00015581350.012
negative regulation of programmed cell deathGO:00430693210.012
nuclear divisionGO:00002801280.011
reactive nitrogen species metabolic processGO:200105730.011
chloride transportGO:0006821410.011
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.011
lamellipodium organizationGO:0097581300.011
actin filament organizationGO:00070151280.011
regulation of endopeptidase activityGO:00525481700.011
regulation of dephosphorylationGO:0035303960.011
positive regulation of developmental processGO:00510943140.011
meiosis iGO:000712740.011
cellular response to dna damage stimulusGO:00069743790.011
regulation of rho protein signal transductionGO:0035023790.011
positive regulation of cell differentiationGO:00455972110.011
negative regulation of cell proliferationGO:00082852280.011
organ formationGO:004864530.011
negative regulation of cellular amine metabolic processGO:003323930.011
regulation of synaptic plasticityGO:004816730.011
nuclear transportGO:00511691790.011
positive regulation of neural precursor cell proliferationGO:200017920.011
wnt signaling pathwayGO:00160551560.011
lipid localizationGO:00108761060.011
blastoderm segmentationGO:000735020.011
negative regulation of cellular amino acid metabolic processGO:004576320.011
glycerophospholipid metabolic processGO:0006650840.011
protein localization to nucleusGO:00345041360.011
regulation of cell migrationGO:00303342890.011
i kappab kinase nf kappab signalingGO:00072491660.011
establishment of protein localization to plasma membraneGO:0090002680.011
ribonucleoside monophosphate metabolic processGO:00091611870.011
cell projection morphogenesisGO:00488581290.011
organic hydroxy compound metabolic processGO:19016151470.011
cytokine productionGO:00018162470.011
pancreatic juice secretionGO:003015740.011
negative regulation of protein modification processGO:00314002000.011
protein acylationGO:00435431380.011
cellular chemical homeostasisGO:00550821800.011
cellular macromolecular complex assemblyGO:00346223240.011
organic acid biosynthetic processGO:0016053970.011
posttranscriptional regulation of gene expressionGO:00106082130.011
neuroblast proliferationGO:000740540.011
positive regulation of rho gtpase activityGO:0032321560.011
mrna metabolic processGO:00160711750.010
circadian behaviorGO:004851220.010
macromolecule methylationGO:0043414970.010
modification dependent protein catabolic processGO:00199412090.010
symbiosis encompassing mutualism through parasitismGO:00444031560.010
meiotic chromosome segregationGO:004513240.010
protein localization to plasma membraneGO:0072659930.010
protein targeting to nucleusGO:00447441040.010
circulatory system developmentGO:00723592620.010
regulation of protein catabolic processGO:00421761550.010
peptidyl tyrosine phosphorylationGO:00181081700.010
regulation of mitosisGO:0007088630.010
chromosome segregationGO:00070591140.010
rna processingGO:00063962550.010
protein secretionGO:0009306980.010
negative regulation of cytokine productionGO:0001818820.010
positive regulation of secretionGO:00510471160.010
immune response activating signal transductionGO:0002757900.010
positive regulation of rab gtpase activityGO:0032851390.010
neurogenesisGO:00220081690.010
regulation of actin filament bundle assemblyGO:0032231360.010
positive regulation of defense responseGO:0031349870.010
metal ion transportGO:00300012720.010
monocarboxylic acid biosynthetic processGO:0072330670.010
cell cycle phase transitionGO:00447701730.010

PLEKHM2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.038
immune system diseaseDOID:29141550.035
central nervous system diseaseDOID:3311860.022
nervous system diseaseDOID:8634310.022
muscular diseaseDOID:00800001140.020
myopathyDOID:4231040.020
muscle tissue diseaseDOID:661130.020
neurodegenerative diseaseDOID:12891020.015
connective tissue diseaseDOID:651090.014
bone diseaseDOID:0080001880.014
disease of metabolismDOID:00146672950.013
muscular dystrophyDOID:9884510.012
hypersensitivity reaction diseaseDOID:0060056250.012
cancerDOID:1621670.011
disease of cellular proliferationDOID:145661740.011
organ system cancerDOID:00506861640.011
sensory system diseaseDOID:00501552030.011