Homo sapiens

166 known processes

RIPK2

receptor-interacting serine-threonine kinase 2

(Aliases: GIG30,CARDIAK,RIP2,RICK,CCK,CARD3)

RIPK2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to muramyl dipeptideGO:007122531.000
i kappab kinase nf kappab signalingGO:00072491661.000
detection of muramyl dipeptideGO:003249811.000
positive regulation of i kappab kinase nf kappab signalingGO:00431231321.000
positive regulation of mhc class i biosynthetic processGO:004534541.000
regulation of i kappab kinase nf kappab signalingGO:00431221621.000
response to cytokineGO:00340972321.000
Human Mouse
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557220.999
Human Mouse
positive regulation of interleukin 1 beta secretionGO:0050718110.999
defense response to bacteriumGO:0042742630.998
Mouse
immune response activating signal transductionGO:0002757900.998
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.998
positive regulation of myeloid leukocyte differentiationGO:0002763240.997
Human
jnk cascadeGO:0007254800.997
Human Mouse
positive regulation of stress activated protein kinase signaling cascadeGO:0070304610.996
Human Mouse
regulation of jnk cascadeGO:0046328730.994
Human Mouse
regulation of cytokine productionGO:00018172320.990
Human Mouse
positive regulation of cytokine productionGO:00018191670.989
Human Mouse
positive regulation of cysteine type endopeptidase activityGO:2001056790.986
interleukin 8 productionGO:0032637510.986
Human
positive regulation of stress activated mapk cascadeGO:0032874600.985
Human Mouse
innate immune responseGO:00450871780.984
positive regulation of nf kappab transcription factor activityGO:0051092810.983
positive regulation of defense responseGO:0031349870.980
cytokine productionGO:00018162470.977
Human Mouse
positive regulation of production of molecular mediator of immune responseGO:0002702110.975
activation of immune responseGO:00022531140.974
regulation of proteolysisGO:00301622930.973
positive regulation of programmed cell deathGO:00430682490.971
Human Mouse
regulation of macrophage differentiationGO:004564990.968
Human
response to nitrogen compoundGO:19016981840.962
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.960
regulation of peptidase activityGO:00525471800.957
regulation of cellular response to stressGO:00801352440.955
Human Mouse
toll like receptor 2 signaling pathwayGO:003413440.950
regulation of endopeptidase activityGO:00525481700.947
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.940
Human
negative regulation of apoptotic processGO:00430663160.933
Human
positive regulation of innate immune responseGO:0045089790.931
detection of peptidoglycanGO:003249910.930
response to biotic stimulusGO:00096072760.929
Mouse
positive regulation of apoptotic signaling pathwayGO:2001235700.928
Human
extrinsic apoptotic signaling pathwayGO:00971911190.927
Human
regulation of sequence specific dna binding transcription factor activityGO:00510902110.924
regulation of innate immune responseGO:0045088970.917
activation of innate immune responseGO:0002218550.914
nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043140.910
detection of stimulusGO:0051606850.906
positive regulation of jnk cascadeGO:0046330520.894
Human Mouse
mhc class i biosynthetic processGO:004534140.893
peptidyl serine autophosphorylationGO:003628920.891
Human
regulation of cytokine production involved in immune responseGO:0002718220.891
cytokine mediated signaling pathwayGO:00192211090.885
Mouse
negative regulation of cell deathGO:00605483450.883
Human
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238260.882
Human
interleukin 6 productionGO:0032635370.874
Mouse
regulation of stress activated protein kinase signaling cascadeGO:0070302850.867
Human Mouse
negative regulation of i kappab kinase nf kappab signalingGO:0043124320.867
Human
myeloid cell differentiationGO:00300991170.858
Human
detection of biotic stimulusGO:0009595210.856
detection of other organismGO:0098543130.852
erk1 and erk2 cascadeGO:00703711040.850
Mouse
defense response to other organismGO:00985421290.837
Mouse
nucleotide binding domain leucine rich repeat containing receptor signaling pathwayGO:003587250.835
detection of external biotic stimulusGO:0098581190.823
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.820
interleukin 1 beta secretionGO:0050702150.814
regulation of myeloid leukocyte differentiationGO:0002761390.808
Human
positive regulation of tumor necrosis factor productionGO:0032760210.792
Human Mouse
positive regulation of interleukin 6 productionGO:0032755210.782
Mouse
response to tumor necrosis factorGO:0034612760.780
Human
positive regulation of apoptotic processGO:00430652460.780
Human Mouse
positive regulation of myeloid cell differentiationGO:0045639390.780
Human
positive regulation of proteolysisGO:00458621420.777
cytokine metabolic processGO:0042107380.775
regulation of cysteine type endopeptidase activityGO:20001161270.768
regulation of defense responseGO:00313471540.767
negative regulation of protein metabolic processGO:00512483910.747
regulation of erk1 and erk2 cascadeGO:0070372990.745
Mouse
innate immune response activating signal transductionGO:0002758480.737
response to abiotic stimulusGO:00096283360.722
regulation of leukocyte activationGO:00026941150.715
Mouse
positive regulation of cell deathGO:00109422630.709
Human Mouse
protein heterooligomerizationGO:0051291160.703
Human
interleukin 1 beta productionGO:0032611220.700
regulation of interleukin 1 secretionGO:0050704140.691
regulation of interleukin 1 beta secretionGO:0050706120.690
detection of bacteriumGO:0016045130.688
positive regulation of necroptotic processGO:006054520.682
Human
cellular macromolecule catabolic processGO:00442653800.680
Human
cell type specific apoptotic processGO:00972851250.679
regulation of stress activated mapk cascadeGO:0032872840.678
Human Mouse
regulation of immune responseGO:00507762010.660
positive regulation of interleukin 1 beta productionGO:0032731130.660
cellular response to external stimulusGO:00714961110.651
nucleotide binding oligomerization domain containing signaling pathwayGO:007042340.648
regulation of mhc class i biosynthetic processGO:004534340.634
regulation of reactive oxygen species metabolic processGO:2000377410.625
immune system developmentGO:00025201950.624
Human Mouse
release of cytoplasmic sequestered nf kappabGO:000858840.617
positive regulation of immune system processGO:00026842830.617
proteolysis involved in cellular protein catabolic processGO:00516032440.616
interleukin 1 secretionGO:0050701180.614
programmed necrotic cell deathGO:0097300180.614
Human
hemopoiesisGO:00300971800.608
Human Mouse
negative regulation of apoptotic signaling pathwayGO:2001234970.607
Human
stress activated protein kinase signaling cascadeGO:0031098940.603
Human Mouse
cellular amino acid metabolic processGO:00065201160.592
regulation of leukocyte differentiationGO:1902105610.589
Human Mouse
regulation of myeloid cell differentiationGO:0045637810.587
Human
cellular protein catabolic processGO:00442572610.575
Human
regulation of protein serine threonine kinase activityGO:00719001790.569
immune response regulating signaling pathwayGO:0002764970.560
positive regulation of interleukin 1 productionGO:0032732140.552
positive regulation of cell proliferationGO:00082843010.552
Mouse
regulation of apoptotic signaling pathwayGO:20012331750.548
Human
positive regulation of protein polyubiquitinationGO:190291630.544
positive regulation of endopeptidase activityGO:0010950840.540
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.540
cellular response to biotic stimulusGO:0071216710.536
Mouse
signal transduction involved in mitotic dna damage checkpointGO:1902402130.520
regulation of nucleoside transportGO:003224210.510
Human
myeloid leukocyte differentiationGO:0002573600.501
Human
positive regulation of cellular amino acid metabolic processGO:004576430.497
interleukin 1 productionGO:0032612260.496
secretionGO:00469032540.496
production of molecular mediator of immune responseGO:0002440370.494
regulation of lymphocyte activationGO:00512491030.493
Mouse
protein ubiquitinationGO:00165673140.489
establishment of protein localization to organelleGO:00725941720.487
positive regulation of immune responseGO:00507781590.484
protein secretionGO:0009306980.472
regulation of protein monoubiquitinationGO:190252510.471
positive regulation of protein phosphorylationGO:00019343130.470
positive regulation of humoral immune responseGO:000292230.457
carbohydrate derivative transportGO:1901264200.454
Human
positive regulation of t cell cytokine productionGO:000272640.442
regulation of protein linear polyubiquitinationGO:190252820.435
response to external biotic stimulusGO:00432072610.426
Mouse
response to organonitrogen compoundGO:00102431560.424
defense responseGO:00069523150.409
regulation of immune effector processGO:0002697910.404
Mouse
negative regulation of peptidase activityGO:0010466910.401
apoptotic signaling pathwayGO:00971902680.397
Human
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.395
positive regulation of interleukin 17 productionGO:003274080.395
trail activated apoptotic signaling pathwayGO:003646240.392
response to virusGO:00096151260.381
regulation of interleukin 8 productionGO:0032677490.378
Human
positive regulation of cytokine production involved in immune responseGO:000272060.373
tumor necrosis factor superfamily cytokine productionGO:0071706450.371
Human Mouse
cytokine production involved in immune responseGO:0002367270.370
reactive oxygen species metabolic processGO:0072593750.362
negative regulation of interleukin 6 biosynthetic processGO:004540930.358
regulation of kinase activityGO:00435493140.357
Human
positive regulation of protein linear polyubiquitinationGO:190253020.356
intrinsic apoptotic signaling pathwayGO:00971931270.353
positive regulation of leukocyte mediated immunityGO:0002705240.352
response to uvGO:0009411730.343
response to lipidGO:00339932060.341
Mouse
negative regulation of cellular protein metabolic processGO:00322693530.335
nitrogen compound transportGO:00717051910.333
Human
type i interferon signaling pathwayGO:0060337110.331
regulation of cell differentiationGO:00455953930.329
Human Mouse
pattern recognition receptor signaling pathwayGO:0002221480.323
hematopoietic or lymphoid organ developmentGO:00485341860.321
Human Mouse
negative regulation of secretion by cellGO:1903531520.319
response to lipopolysaccharideGO:0032496700.313
Mouse
negative regulation of cell proliferationGO:00082852280.308
positive regulation of hydrolase activityGO:00513453310.308
Human
modification dependent protein catabolic processGO:00199412090.308
leukocyte differentiationGO:0002521980.302
Human Mouse
protein oligomerizationGO:00512591730.300
Human
negative regulation of protein modification processGO:00314002000.300
dendritic cell antigen processing and presentationGO:000246810.297
secretion by cellGO:00329402260.293
cellular response to oxygen containing compoundGO:19017012760.292
positive regulation of interleukin 2 productionGO:0032743110.288
Mouse
positive regulation of cell activationGO:0050867810.285
Mouse
defense response to virusGO:0051607710.280
b cell homeostasisGO:000178210.279
nucleoside transportGO:001585880.270
Human
activation of nf kappab inducing kinase activityGO:000725090.268
stress activated mapk cascadeGO:0051403930.264
Human Mouse
positive regulation of secretion by cellGO:19035321080.263
response to molecule of bacterial originGO:0002237820.262
Mouse
protein polyubiquitinationGO:00002091100.262
circadian sleep wake cycle sleepGO:005080220.261
positive regulation of intracellular protein transportGO:0090316760.258
cardiovascular system developmentGO:00723582620.257
dna damage checkpointGO:0000077680.257
detection of molecule of bacterial originGO:0032490100.255
negative regulation of multicellular organismal processGO:00512413170.255
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:200126910.253
response to organic cyclic compoundGO:00140702040.250
Mouse
cell cycle phase transitionGO:00447701730.248
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.243
cellular response to lipidGO:00713961270.243
Mouse
protein processingGO:00164852260.241
protein catabolic processGO:00301633250.238
Human
amine metabolic processGO:0009308440.235
multicellular organismal agingGO:001025930.235
positive regulation of protein bindingGO:0032092240.234
regulation of cell cycleGO:00517263930.228
positive regulation of developmental processGO:00510943140.228
Human Mouse
mitotic g1 s transition checkpointGO:0044819170.226
positive regulation of necrotic cell deathGO:001094040.225
Human
ripoptosome assemblyGO:009734310.224
Human
neurological system processGO:00508771630.224
interleukin 2 productionGO:0032623200.222
Mouse
compound eye developmentGO:004874910.222
mitotic g1 dna damage checkpointGO:0031571170.219
regulation of transcription regulatory region dna bindingGO:2000677150.217
locomotory behaviorGO:000762610.216
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237520.213
Human
mitochondrion organizationGO:00070051560.212
natural killer cell apoptotic processGO:007024610.210
acute inflammatory responseGO:0002526210.208
negative regulation of endopeptidase activityGO:0010951840.202
intrinsic apoptotic signaling pathway in response to oxidative stressGO:0008631210.200
regulation of anion transportGO:0044070250.198
Human
cation homeostasisGO:00550801890.196
protein modification by small protein conjugationGO:00324463420.196
regulation of protein modification by small protein conjugation or removalGO:19033201070.193
protein homooligomerizationGO:00512601000.192
Human
positive regulation of osteoclast differentiationGO:004567290.191
cellular response to oxidative stressGO:0034599850.189
determination of adult lifespanGO:000834020.188
signal transduction involved in dna damage checkpointGO:0072422150.187
response to interferon gammaGO:0034341390.187
negative regulation of phosphorus metabolic processGO:00105632670.186
regulation of wnt signaling pathwayGO:00301111230.182
response to activityGO:001482300.182
negative regulation of catalytic activityGO:00430863350.180
regulation of lymphocyte apoptotic processGO:0070228150.179
peptidyl tyrosine phosphorylationGO:00181081700.177
regulation of response to dna damage stimulusGO:2001020940.176
signal transduction involved in mitotic g1 dna damage checkpointGO:0072431100.175
regulation of interleukin 1 beta productionGO:0032651180.173
system processGO:00030083490.171
leukocyte activationGO:00453211640.170
Mouse
response to peptidoglycanGO:003249430.170
Mouse
negative regulation of intracellular signal transductionGO:19025321830.169
Human
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.168
response to oxygen containing compoundGO:19017003690.165
negative regulation of cell cycle processGO:00109481210.164
immune effector processGO:00022521590.164
Mouse
canonical wnt signaling pathwayGO:00600701160.162
positive regulation of peptidase activityGO:0010952880.162
regulation of mitotic cell cycleGO:00073461890.159
positive regulation of cell differentiationGO:00455972110.157
Human Mouse
protein maturationGO:00516042330.154
regulation of cytokine biosynthetic processGO:0042035350.153
response to other organismGO:00517072610.151
Mouse
negative regulation of cell cycle g1 s phase transitionGO:1902807290.151
detection of chemical stimulusGO:0009593550.150
positive regulation of reactive oxygen species biosynthetic processGO:190342820.148
activation of cysteine type endopeptidase activityGO:0097202570.148
zymogen activationGO:0031638700.146
cellular response to lipopolysaccharideGO:0071222570.145
Mouse
cellular amide metabolic processGO:0043603690.145
mapk cascadeGO:00001652880.142
Human Mouse
regulation of protein localizationGO:00328802960.141
adaptive immune responseGO:0002250490.141
Mouse
ion homeostasisGO:00508012300.140
negative regulation of interleukin 1 secretionGO:005071140.140
positive regulation of protein k48 linked ubiquitinationGO:190252410.139
protein autophosphorylationGO:00467771230.139
Human
regulation of transmembrane transporter activityGO:0022898740.139
Human
negative regulation of interleukin 1 beta secretionGO:005071320.138
spermatid developmentGO:000728640.137
regulation of map kinase activityGO:00434051080.137
negative regulation of mitotic cell cycleGO:00459301020.136
immune responseGO:00069553070.136
protein k63 linked ubiquitinationGO:0070534310.136
mitotic cell cycleGO:00002783260.135
positive regulation of cellular amine metabolic processGO:003324070.135
negative regulation of phosphate metabolic processGO:00459362670.134
modification dependent macromolecule catabolic processGO:00436322120.133
peptide metabolic processGO:0006518510.133
negative regulation of programmed cell deathGO:00430693210.132
Human
regulation of protein ubiquitinationGO:0031396950.130
t cell cytokine productionGO:0002369120.129
negative regulation of cell cycle phase transitionGO:1901988890.128
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.128
regulation of canonical wnt signaling pathwayGO:0060828880.127
intracellular signal transduction involved in g1 dna damage checkpointGO:1902400100.125
positive regulation of leukocyte differentiationGO:1902107370.125
Human Mouse
protein importGO:00170381300.124
negative regulation of g1 s transition of mitotic cell cycleGO:2000134290.124
negative regulation of cell cycleGO:00457861930.124
positive regulation of cell cycle arrestGO:0071158230.124
positive regulation of secretionGO:00510471160.123
lymphocyte apoptotic processGO:0070227200.123
negative regulation of phosphorylationGO:00423261740.122
proteasomal protein catabolic processGO:00104981760.122
defense response to gram positive bacteriumGO:0050830290.121
Mouse
release of cytochrome c from mitochondriaGO:0001836350.119
midgut developmentGO:000749410.119
cellular response to nitrogen compoundGO:19016991440.117
protein linear polyubiquitinationGO:009703950.116
apoptotic mitochondrial changesGO:0008637570.116
protein autoprocessingGO:001654040.116
syncytium formation by plasma membrane fusionGO:000076820.115
regulation of interleukin 1 productionGO:0032652210.113
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001239200.113
positive regulation of phosphorylationGO:00423273940.112
negative regulation of acute inflammatory responseGO:000267430.111
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.111
positive regulation of protein localization to nucleusGO:1900182480.110
antigen processing and presentationGO:0019882330.109
positive regulation of protein transportGO:00512221350.109
response to radiationGO:00093141510.108
negative regulation of cysteine type endopeptidase activityGO:2000117480.106
dna damage response signal transduction by p53 class mediatorGO:0030330440.105
peripheral nervous system developmentGO:000742220.104
cellular response to radiationGO:0071478650.103
response to toxic substanceGO:0009636370.102
response to hydrogen peroxideGO:0042542400.102
regulation of transferase activityGO:00513383550.101
Human
signal transduction involved in dna integrity checkpointGO:0072401150.101
interleukin 17 productionGO:0032620120.100
signal transduction involved in cell cycle checkpointGO:0072395160.100
ubiquitin dependent protein catabolic processGO:00065112060.099
regulation of establishment of protein localizationGO:00702012420.097
regulation of t cell cytokine productionGO:0002724100.097
neuron deathGO:0070997650.096
regulation of t cell proliferationGO:0042129420.095
Mouse
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrestGO:000697790.095
positive regulation of lymphocyte activationGO:0051251730.095
Mouse
regulation of acute inflammatory responseGO:0002673130.094
response to mechanical stimulusGO:0009612510.094
positive regulation of mapk cascadeGO:00434101900.093
Human Mouse
positive regulation of erk1 and erk2 cascadeGO:0070374750.093
Mouse
circadian sleep wake cycle processGO:002241020.092
t cell receptor signaling pathwayGO:0050852210.092
Mouse
intracellular receptor signaling pathwayGO:00305221040.092
cell cycle checkpointGO:00000751170.091
regulation of response to woundingGO:19030341010.091
negative regulation of hydrolase activityGO:00513461820.090
reactive nitrogen species metabolic processGO:200105730.090
regulation of reactive oxygen species biosynthetic processGO:190342630.088
osteoclast differentiationGO:0030316210.088
small gtpase mediated signal transductionGO:0007264780.088
negative regulation of nf kappab transcription factor activityGO:0032088510.087
immune response activating cell surface receptor signaling pathwayGO:0002429450.087
Mouse
cellular response to dna damage stimulusGO:00069743790.087
mitotic cell cycle phase transitionGO:00447721620.087
positive regulation of protein homodimerization activityGO:009007350.086
regulation of response to external stimulusGO:00321012220.085
positive regulation of protein ubiquitinationGO:0031398530.085
positive regulation of interferon gamma mediated signaling pathwayGO:006033520.085
cellular response to interferon gammaGO:0071346240.085
developmental programmed cell deathGO:001062330.084
autophagic cell deathGO:004810230.083
wnt signaling pathwayGO:00160551560.083
single organism nuclear importGO:19025931040.083
regulation of protein kinase activityGO:00458592890.083
Human
regulation of interleukin 8 secretionGO:2000482130.083
signal transduction involved in mitotic dna integrity checkpointGO:1902403130.082
cellular response to mechanical stimulusGO:0071260390.082
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:200126720.081
regulation of inflammatory responseGO:0050727460.081
interferon gamma mediated signaling pathwayGO:006033370.080
regulation of transporter activityGO:0032409820.080
Human
regulation of nik nf kappab signalingGO:1901222110.080
lymphocyte activationGO:00466491330.079
Mouse
negative regulation of protein processingGO:00109551420.079
regulation of production of molecular mediator of immune responseGO:0002700250.079
response to oxygen levelsGO:00704821000.078
positive regulation of nf kappab import into nucleusGO:0042346130.077
cytoplasmic transportGO:00164823790.077
cellular ketone metabolic processGO:0042180800.076
negative regulation of reactive oxygen species metabolic processGO:2000378110.076
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.075
signal transduction in response to dna damageGO:0042770570.075
mitotic cell cycle checkpointGO:0007093680.075
nucleobase containing compound transportGO:0015931510.073
Human
rhythmic behaviorGO:000762220.072
regulation of oxidoreductase activityGO:0051341430.072
regulation of lymphocyte mediated immunityGO:0002706330.072
regulation of type i interferon mediated signaling pathwayGO:006033890.072
vasodilationGO:004231140.072
regulation of cell cycle g1 s phase transitionGO:1902806420.071
midbrain developmentGO:0030901450.071
cellular amine metabolic processGO:0044106410.071
response to woundingGO:00096111680.070
regulation of cell cycle phase transitionGO:19019871260.070
positive regulation of transportGO:00510503360.070
protein k48 linked ubiquitinationGO:0070936380.069
circadian sleep wake cycleGO:004274520.069
positive regulation of adaptive immune responseGO:0002821210.068
Mouse
regulation of antimicrobial humoral responseGO:000275910.068
leukocyte apoptotic processGO:0071887310.067
nuclear importGO:00511701060.067
regulation of transcription factor import into nucleusGO:0042990390.067
cellular response to light stimulusGO:0071482340.066
activation of protein kinase activityGO:0032147900.066
Human
dna integrity checkpointGO:0031570710.066
peptidyl threonine phosphorylationGO:0018107410.065
regulation of leukocyte apoptotic processGO:2000106250.065
toll signaling pathwayGO:000806320.065
regulation of protein processingGO:00706131500.065
cellular chemical homeostasisGO:00550821800.064
reproductive processGO:00224141060.064
positive regulation of protein import into nucleusGO:0042307460.063
regulation of protein localization to nucleusGO:1900180850.063
regulation of cytoplasmic transportGO:19036491490.063
organonitrogen compound biosynthetic processGO:19015662000.063
necrotic cell deathGO:0070265210.062
Human
inflammatory responseGO:0006954790.062
cellular response to abiotic stimulusGO:00712141170.062
negative regulation of response to external stimulusGO:0032102830.061
spermatid differentiationGO:004851540.061
regulation of dendritic cell antigen processing and presentationGO:000260410.061
positive regulation of gtp catabolic processGO:00331261660.061
purine ribonucleoside metabolic processGO:00461284370.060
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001240160.060
positive regulation of interleukin 1 secretionGO:0050716110.060
purine nucleoside triphosphate catabolic processGO:00091463920.059
positive regulation of immune effector processGO:0002699400.058
Mouse
post embryonic developmentGO:000979120.058
transcription factor import into nucleusGO:0042991400.058
cell cycle g1 s phase transitionGO:0044843800.058
positive regulation of cdc42 gtpase activityGO:004308960.057
regulation of osteoclast differentiationGO:0045670180.057
positive regulation of cytokine mediated signaling pathwayGO:0001961120.057
Mouse
regulation of secretion by cellGO:19035301770.056
regulation of dna bindingGO:0051101370.056
fibril organizationGO:0097435100.055
Human
positive regulation of macrophage differentiationGO:004565170.055
Human
negative regulation of mitotic cell cycle phase transitionGO:1901991850.055
negative regulation of inflammatory responseGO:0050728220.055
regulation of adaptive immune responseGO:0002819330.054
Mouse
gtp metabolic processGO:00460392390.054
positive regulation of lymphocyte mediated immunityGO:0002708230.054
regulation of leukocyte proliferationGO:0070663670.054
Mouse
positive regulation of canonical wnt signaling pathwayGO:0090263330.053
positive regulation of jak stat cascadeGO:0046427350.053
negative regulation of defense responseGO:0031348470.053
nucleotide catabolic processGO:00091664080.053
purine ribonucleoside triphosphate metabolic processGO:00092054110.052
regulation of protein transportGO:00512232130.052
response to antibioticGO:0046677150.052
protein localization to nucleusGO:00345041360.052
positive regulation of bindingGO:0051099450.052
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043154460.052
cellular response to endogenous stimulusGO:00714953360.051
defense response to gram negative bacteriumGO:0050829140.051
negative regulation of proteolysisGO:00458611320.051
positive regulation of protein secretionGO:0050714600.050
circulatory system developmentGO:00723592620.050
regulation of cell cycle processGO:00105642660.049
positive regulation of transcription factor import into nucleusGO:0042993250.049
regulation of defense response to virusGO:0050688330.049
protein targetingGO:00066051870.048
cellular response to tumor necrosis factorGO:0071356630.048
Human
amide biosynthetic processGO:0043604150.048
cellular response to uvGO:0034644320.048
regulation of secretionGO:00510461940.047
membrane hyperpolarizationGO:006008110.047
negative regulation of immune system processGO:00026831360.047
spermatogenesisGO:0007283220.047
regulation of defense response to bacteriumGO:190042420.046
female gamete generationGO:000729220.046
nucleoside triphosphate metabolic processGO:00091414220.046
regulation of toll signaling pathwayGO:000859210.046
cell cycle arrestGO:0007050710.046
positive regulation of b cell activationGO:0050871170.046
membrane protein proteolysisGO:0033619380.046
response to oxidative stressGO:00069791210.046
response to extracellular stimulusGO:0009991850.045
regulation of protein autophosphorylationGO:0031952150.045
negative regulation of response to cytokine stimulusGO:0060761250.044
regulation of protein homodimerization activityGO:004349690.044
single organism reproductive processGO:0044702980.044
circadian behaviorGO:004851220.044
digestive system processGO:0022600170.044
regulation of protein secretionGO:0050708860.044
positive regulation of cell cycle processGO:00900681060.044
oxidation reduction processGO:00551143960.044
positive regulation of response to interferon gammaGO:006033220.044
male gamete generationGO:0048232220.043
multicellular organismal reproductive processGO:0048609400.043
signal transduction involved in mitotic cell cycle checkpointGO:0072413130.042
purine containing compound catabolic processGO:00725234110.042
regulation of necroptotic processGO:006054470.042
Human

RIPK2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
gastrointestinal system diseaseDOID:77360.394
immune system diseaseDOID:29141550.251
hypersensitivity reaction diseaseDOID:0060056250.251
intestinal diseaseDOID:5295140.068
disease of cellular proliferationDOID:145661740.049
organ system cancerDOID:00506861640.049
cancerDOID:1621670.049