Homo sapiens

28 known processes

SPTBN5

spectrin, beta, non-erythrocytic 5

(Aliases: BSPECV,HUBSPECV,HUSPECV)

SPTBN5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
system processGO:00030083490.120
cellular amino acid metabolic processGO:00065201160.107
g protein coupled receptor signaling pathwayGO:00071862070.107
regulation of cellular amino acid metabolic processGO:000652160.063
post embryonic developmentGO:000979120.060
cell adhesionGO:00071553250.056
positive regulation of transportGO:00510503360.056
ribonucleoside catabolic processGO:00424544060.055
regulation of cellular ketone metabolic processGO:0010565500.055
purine containing compound catabolic processGO:00725234110.054
secretionGO:00469032540.054
immune responseGO:00069553070.054
biological adhesionGO:00226103310.052
defense responseGO:00069523150.051
purine ribonucleotide catabolic processGO:00091544040.050
nucleoside phosphate catabolic processGO:19012924120.050
regulation of cellular amine metabolic processGO:0033238110.048
amine metabolic processGO:0009308440.048
cellular amine metabolic processGO:0044106410.046
nucleotide catabolic processGO:00091664080.045
cellular ketone metabolic processGO:0042180800.045
purine nucleotide catabolic processGO:00061954050.045
ribonucleotide catabolic processGO:00092614050.045
glycosyl compound catabolic processGO:19016584130.044
organophosphate catabolic processGO:00464344300.044
response to biotic stimulusGO:00096072760.044
ribonucleoside triphosphate metabolic processGO:00091994120.044
purine nucleoside triphosphate catabolic processGO:00091463920.043
negative regulation of multicellular organismal processGO:00512413170.043
purine ribonucleoside catabolic processGO:00461303980.043
response to abiotic stimulusGO:00096283360.043
positive regulation of cellular component organizationGO:00511303760.043
purine ribonucleoside triphosphate metabolic processGO:00092054110.042
response to external biotic stimulusGO:00432072610.042
neurological system processGO:00508771630.042
regulation of secretion by cellGO:19035301770.042
purine nucleoside triphosphate metabolic processGO:00091444120.042
purine ribonucleoside metabolic processGO:00461284370.042
purine ribonucleoside triphosphate catabolic processGO:00092073910.042
nucleoside catabolic processGO:00091644080.040
regulation of nucleotide metabolic processGO:00061402690.039
vesicle mediated transportGO:00161923710.038
Human Fly
nucleoside triphosphate metabolic processGO:00091414220.037
positive regulation of catabolic processGO:00098963100.037
purine nucleoside catabolic processGO:00061523980.037
regulation of cellular component biogenesisGO:00440872810.037
positive regulation of phosphorylationGO:00423273940.037
regulation of cell motilityGO:20001452990.037
small gtpase mediated signal transductionGO:0007264780.036
regulation of secretionGO:00510461940.036
secretion by cellGO:00329402260.036
female gamete generationGO:000729220.035
cellular component morphogenesisGO:00329893140.035
lipid metabolic processGO:00066293810.035
ribonucleoside triphosphate catabolic processGO:00092033910.035
response to oxygen containing compoundGO:19017003690.034
chemical homeostasisGO:00488783060.034
regulation of cell cycleGO:00517263930.034
ion homeostasisGO:00508012300.034
cation transportGO:00068123310.034
transmembrane transportGO:00550853990.034
regulation of locomotionGO:00400123290.034
regulation of cell differentiationGO:00455953930.033
ion transmembrane transportGO:00342203380.033
negative regulation of cellular component organizationGO:00511292350.033
regulation of response to external stimulusGO:00321012220.033
ras protein signal transductionGO:0007265730.032
regulation of protein localizationGO:00328802960.032
positive regulation of hydrolase activityGO:00513453310.032
nucleoside triphosphate catabolic processGO:00091433940.031
regulation of anatomical structure morphogenesisGO:00226032860.031
metal ion transportGO:00300012720.031
negative regulation of catalytic activityGO:00430863350.031
positive regulation of cellular amine metabolic processGO:003324070.031
regulation of cellular component movementGO:00512703340.031
determination of adult lifespanGO:000834020.030
positive regulation of cellular amino acid metabolic processGO:004576430.030
response to other organismGO:00517072610.030
multicellular organismal agingGO:001025930.030
oogenesisGO:004847720.030
organic hydroxy compound metabolic processGO:19016151470.030
divalent inorganic cation transportGO:00725111580.030
positive regulation of purine nucleotide metabolic processGO:19005442270.029
positive regulation of cellular catabolic processGO:00313312840.029
protein processingGO:00164852260.029
positive regulation of protein phosphorylationGO:00019343130.029
enzyme linked receptor protein signaling pathwayGO:00071673030.029
rho protein signal transductionGO:0007266260.029
nitrogen compound transportGO:00717051910.028
organonitrogen compound biosynthetic processGO:19015662000.028
regulation of purine nucleotide metabolic processGO:19005422640.028
memoryGO:000761330.028
immune effector processGO:00022521590.028
guanosine containing compound catabolic processGO:19010692390.028
cell morphogenesisGO:00009022960.028
regulation of system processGO:00440571010.027
locomotory behaviorGO:000762610.027
negative regulation of developmental processGO:00510932470.027
cytoplasmic transportGO:00164823790.027
Human
protein maturationGO:00516042330.027
membrane organizationGO:00610242920.027
Human
response to nitrogen compoundGO:19016981840.027
cellular response to endogenous stimulusGO:00714953360.027
regulation of hormone levelsGO:00108171250.027
neuromuscular junction developmentGO:000752830.027
regulation of transferase activityGO:00513383550.026
regulation of gtp catabolic processGO:00331241800.026
response to woundingGO:00096111680.026
Fly
regulation of kinase activityGO:00435493140.026
regulation of establishment of protein localizationGO:00702012420.026
regulation of ion transportGO:00432691890.026
regulation of cell migrationGO:00303342890.026
single organism cell adhesionGO:00986021790.025
gtp catabolic processGO:00061842370.025
inorganic ion transmembrane transportGO:00986602310.025
organophosphate biosynthetic processGO:00904071630.025
innate immune responseGO:00450871780.025
regulation of cell adhesionGO:00301551660.025
segmentationGO:003528240.025
cell cell signalingGO:00072671550.025
positive regulation of nucleotide metabolic processGO:00459812300.025
lipid biosynthetic processGO:00086101770.025
negative regulation of phosphorus metabolic processGO:00105632670.025
cellular macromolecule catabolic processGO:00442653800.025
regulation of multi organism processGO:00439001570.025
sensory perceptionGO:00076001030.025
mapk cascadeGO:00001652880.025
regulation of mapk cascadeGO:00434082620.024
carbohydrate derivative biosynthetic processGO:19011372070.024
positive regulation of cell differentiationGO:00455972110.024
regulation of cellular response to stressGO:00801352440.024
gtp metabolic processGO:00460392390.024
positive regulation of secretionGO:00510471160.024
positive regulation of secretion by cellGO:19035321080.024
cell developmentGO:00484683280.023
regulation of protein transportGO:00512232130.023
cell projection organizationGO:00300302520.023
positive regulation of mapk cascadeGO:00434101900.023
positive regulation of immune system processGO:00026842830.023
cellular macromolecular complex assemblyGO:00346223240.023
divalent inorganic cation homeostasisGO:00725071360.023
dephosphorylationGO:00163112090.023
positive regulation of developmental processGO:00510943140.023
cellular lipid metabolic processGO:00442553030.022
oocyte developmentGO:004859910.022
regulation of protein kinase activityGO:00458592890.022
single organism cellular localizationGO:19025803320.022
Human
nervous system developmentGO:00073992930.022
metal ion homeostasisGO:00550651690.022
detection of stimulusGO:0051606850.022
regulation of cytoskeleton organizationGO:00514931770.022
regulation of nucleotide catabolic processGO:00308112050.022
epithelium developmentGO:00604292270.021
cytokine productionGO:00018162470.021
guanosine containing compound metabolic processGO:19010682440.021
signal transduction by phosphorylationGO:00230142970.021
positive regulation of transferase activityGO:00513472270.021
cardiovascular system developmentGO:00723582620.021
regulation of nucleoside metabolic processGO:00091182090.021
response to cytokineGO:00340972320.021
circulatory system developmentGO:00723592620.021
negative regulation of protein metabolic processGO:00512483910.021
response to growth factorGO:00708482050.021
cellular protein complex assemblyGO:00436231880.020
taxisGO:00423301570.020
regulation of vesicle mediated transportGO:00606271300.020
neurogenesisGO:00220081690.020
negative regulation of cell deathGO:00605483450.020
negative regulation of cellular protein metabolic processGO:00322693530.020
carbohydrate metabolic processGO:00059752070.020
regulation of proteolysisGO:00301622930.020
regulation of cell cycle processGO:00105642660.020
cellular response to growth factor stimulusGO:00713631970.020
actin filament based processGO:00300292240.020
regulation of cytokine productionGO:00018172320.020
calcium ion homeostasisGO:00550741220.020
response to organic cyclic compoundGO:00140702040.020
calcium ion transportGO:00068161470.020
startle responseGO:000196430.020
regenerationGO:003109940.020
negative regulation of hydrolase activityGO:00513461820.019
regulation of purine nucleotide catabolic processGO:00331212050.019
positive regulation of apoptotic processGO:00430652460.019
oocyte differentiationGO:000999420.019
protein catabolic processGO:00301633250.019
alcohol metabolic processGO:00060661140.019
cellular homeostasisGO:00197251960.019
cellular divalent inorganic cation homeostasisGO:00725031280.019
apoptotic signaling pathwayGO:00971902680.019
cell substrate adhesionGO:00315891320.019
positive regulation of kinase activityGO:00336742040.019
intracellular protein transportGO:00068862700.019
Human
negative regulation of phosphate metabolic processGO:00459362670.019
interspecies interaction between organismsGO:00444191560.019
wound healingGO:00420601150.018
Fly
cation transmembrane transportGO:00986552380.018
single organism membrane organizationGO:00448022680.018
Human
positive regulation of protein kinase activityGO:00458601900.018
regulation of immune responseGO:00507762010.018
protein localization to organelleGO:00333652800.018
response to radiationGO:00093141510.018
generation of neuronsGO:00486991520.018
endocytosisGO:00068971590.018
Fly
divalent metal ion transportGO:00708381520.018
exocytosisGO:0006887710.018
positive regulation of purine nucleotide catabolic processGO:00331231850.018
cellular response to dna damage stimulusGO:00069743790.017
peripheral nervous system developmentGO:000742220.017
positive regulation of nucleotide catabolic processGO:00308131850.017
regulation of growthGO:00400081650.017
cell matrix adhesionGO:0007160850.017
multi organism cellular processGO:00447641560.017
growthGO:00400072020.017
covalent chromatin modificationGO:00165692540.017
endomembrane system organizationGO:00102561960.017
defense response to other organismGO:00985421290.017
small molecule biosynthetic processGO:00442831570.017
histone modificationGO:00165702510.017
inorganic cation transmembrane transportGO:00986621940.017
chromatin modificationGO:00165682980.017
cation homeostasisGO:00550801890.017
regulation of cell developmentGO:00602841610.017
response to organonitrogen compoundGO:00102431560.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.017
response to bacteriumGO:00096171440.017
cellular response to abiotic stimulusGO:00712141170.017
anterior posterior axis specification embryoGO:000859520.017
positive regulation of nucleoside metabolic processGO:00459791860.017
single organismal cell cell adhesionGO:00163371480.017
establishment of protein localization to membraneGO:00901501210.017
Human
cellular protein catabolic processGO:00442572610.017
sulfur compound metabolic processGO:00067901010.016
regulation of synaptic plasticityGO:004816730.016
positive regulation of locomotionGO:00400171860.016
single organism carbohydrate metabolic processGO:00447231930.016
negative regulation of cell proliferationGO:00082852280.016
cell projection morphogenesisGO:00488581290.016
anterior posterior axis specificationGO:000994820.016
adult locomotory behaviorGO:000834410.016
mitotic cell cycleGO:00002783260.016
Human Fly
blastoderm segmentationGO:000735020.016
anion transportGO:00068201610.016
glycoprotein metabolic processGO:00091001100.016
cell part morphogenesisGO:00329901370.016
chemotaxisGO:00069351570.016
positive regulation of cytosolic calcium ion concentrationGO:0007204820.016
purine containing compound biosynthetic processGO:0072522880.016
cell growthGO:00160491600.016
regulation of ras gtpase activityGO:00323181280.016
chromatin organizationGO:00063253510.016
protein oligomerizationGO:00512591730.015
cell activationGO:00017752130.015
positive regulation of programmed cell deathGO:00430682490.015
positive regulation of gtp catabolic processGO:00331261660.015
cellular calcium ion homeostasisGO:00068741170.015
positive regulation of protein transportGO:00512221350.015
regulation of cell growthGO:00015581350.015
proteolysis involved in cellular protein catabolic processGO:00516032440.015
positive regulation of cell migrationGO:00303351720.015
spermatid differentiationGO:004851540.015
regulation of gtpase activityGO:00430871800.015
cell divisionGO:00513011680.015
Human Fly
muscle system processGO:0003012810.015
response to virusGO:00096151260.015
anatomical structure formation involved in morphogenesisGO:00486462840.015
negative regulation of apoptotic processGO:00430663160.015
calcium ion transmembrane transportGO:0070588760.015
positive regulation of cellular component biogenesisGO:00440891580.015
protein targetingGO:00066051870.015
Human
cellular response to cytokine stimulusGO:00713451810.015
negative regulation of cellular amino acid metabolic processGO:004576320.015
cellular response to organic cyclic compoundGO:00714071270.015
regulation of protein complex assemblyGO:00432541470.015
positive regulation of organelle organizationGO:00106381950.015
negative regulation of programmed cell deathGO:00430693210.015
tripartite regional subdivisionGO:000735120.015
negative regulation of cell differentiationGO:00455961710.015
leukocyte activationGO:00453211640.015
associative learningGO:000830610.015
regulation of cell projection organizationGO:00313441070.015
negative regulation of intracellular signal transductionGO:19025321830.015
positive regulation of ras gtpase activityGO:00323201170.014
actin filament organizationGO:00070151280.014
positive regulation of cellular component movementGO:00512721810.014
neurotransmitter secretionGO:000726940.014
positive regulation of cell deathGO:00109422630.014
regulation of small gtpase mediated signal transductionGO:00510561560.014
nuclear transportGO:00511691790.014
cyclic nucleotide metabolic processGO:0009187820.014
ribose phosphate biosynthetic processGO:0046390820.014
purine nucleotide biosynthetic processGO:0006164840.014
cellular response to oxygen containing compoundGO:19017012760.014
regulation of transmembrane transportGO:00347621390.014
plasma membrane organizationGO:00070091150.014
Human
oxidation reduction processGO:00551143960.014
gamma aminobutyric acid signaling pathwayGO:000721430.014
rhythmic behaviorGO:000762220.014
maintenance of locationGO:00512351120.014
steroid metabolic processGO:0008202940.014
positive regulation of cell motilityGO:20001471770.014
regulation of response to woundingGO:19030341010.014
receptor metabolic processGO:0043112810.014
cellular response to histamineGO:007142030.014
ossificationGO:00015031210.014
nucleocytoplasmic transportGO:00069131760.014
modification dependent macromolecule catabolic processGO:00436322120.014
regulation of protein maturationGO:19033171500.014
sensory perception of painGO:001923340.013
osteoblast differentiationGO:0001649920.013
blood circulationGO:00080151130.013
protein localization to plasma membraneGO:0072659930.013
Human
sensory perception of chemical stimulusGO:0007606380.013
lipid transportGO:0006869900.013
cellular metal ion homeostasisGO:00068751460.013
regulation of defense responseGO:00313471540.013
response to inorganic substanceGO:00100351270.013
protein modification by small protein conjugationGO:00324463420.013
nucleotide biosynthetic processGO:00091651090.013
purine ribonucleoside monophosphate metabolic processGO:00091671860.013
regulation of cell morphogenesisGO:00226041530.013
tissue migrationGO:00901301190.013
mitotic cell cycle processGO:19030472860.013
Human Fly
spermatid developmentGO:000728640.013
protein importGO:00170381300.013
negative regulation of organelle organizationGO:00106391260.013
circadian behaviorGO:004851220.013
peptidyl tyrosine modificationGO:00182121700.013
wnt signaling pathwayGO:00160551560.013
hormone transportGO:0009914680.013
regulation of protein processingGO:00706131500.013
cellular component disassemblyGO:0022411920.013
regulation of metal ion transportGO:00109591200.013
purine nucleoside monophosphate metabolic processGO:00091261860.013
matingGO:000761810.013
reactive oxygen species biosynthetic processGO:190340940.013
negative regulation of transportGO:00510511760.013
neuron developmentGO:00486661130.013
regulation of cell activationGO:00508651250.012
actin cytoskeleton organizationGO:00300362070.012
regulation of acrosome reactionGO:006004640.012
regulation of cytoplasmic transportGO:19036491490.012
regulation of dna metabolic processGO:00510521530.012
response to light stimulusGO:0009416870.012
viral processGO:00160321460.012
blood vessel developmentGO:00015681720.012
negative regulation of cellular amine metabolic processGO:003323930.012
sensory perception of tasteGO:0050909360.012
regulation of intracellular transportGO:00323861950.012
cytosolic calcium ion homeostasisGO:0051480890.012
coagulationGO:0050817780.012
behaviorGO:00076101120.012
positive regulation of immune responseGO:00507781590.012
regulation of peptidase activityGO:00525471800.012
epithelial cell differentiationGO:00308551410.012
regulation of protein catabolic processGO:00421761550.012
positive regulation of cytokine productionGO:00018191670.012
cardiac muscle cell contractionGO:008600340.012
purine ribonucleotide biosynthetic processGO:0009152790.012
microtubule based processGO:00070172100.012
epithelial cell migrationGO:00106311190.012
circulatory system processGO:00030131130.012
regulation of actin cytoskeleton organizationGO:00329561160.012
negative regulation of cell cycleGO:00457861930.012
epithelium migrationGO:00901321190.012
modification dependent protein catabolic processGO:00199412090.012
regulation of dephosphorylationGO:0035303960.012
cellular chemical homeostasisGO:00550821800.012
cell projection assemblyGO:00300311260.012
atp metabolic processGO:00460341760.012
endochondral bone morphogenesisGO:006035030.012
salivary gland morphogenesisGO:000743540.012
organic anion transportGO:00157111030.012
positive regulation of cell proliferationGO:00082843010.012
establishment of protein localization to organelleGO:00725941720.012
symbiosis encompassing mutualism through parasitismGO:00444031560.012
detection of chemical stimulusGO:0009593550.012
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
regulation of ras protein signal transductionGO:00465781550.012
hemostasisGO:0007599760.012
visual behaviorGO:000763220.012
central nervous system developmentGO:00074171230.012
negative regulation of secretion by cellGO:1903531520.012
small molecule catabolic processGO:0044282920.012
ameboidal type cell migrationGO:00016671350.012
nucleoside phosphate biosynthetic processGO:19012931090.012
regulation of reactive oxygen species metabolic processGO:2000377410.012
regulation of protein secretionGO:0050708860.012
cellular ion homeostasisGO:00068731680.012
positive regulation of intracellular transportGO:00323881040.012
regulation of mitotic cell cycleGO:00073461890.012
protein secretionGO:0009306980.012
cellular cation homeostasisGO:00300031630.012
response to fungusGO:000962040.012
protein polymerizationGO:0051258710.012
multicellular organismal metabolic processGO:0044236340.011
ribonucleotide biosynthetic processGO:0009260810.011
regulation of endopeptidase activityGO:00525481700.011
reactive oxygen species metabolic processGO:0072593750.011
vasculature developmentGO:00019441810.011
angiogenesisGO:00015251470.011
cellular carbohydrate metabolic processGO:0044262840.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.011
muscle contractionGO:0006936730.011
positive regulation of cytoplasmic transportGO:1903651820.011
organic hydroxy compound biosynthetic processGO:1901617710.011
microtubule cytoskeleton organizationGO:00002261760.011
regulation of peptidyl tyrosine phosphorylationGO:00507301080.011
fatty acid metabolic processGO:00066311150.011
regulation of transmission of nerve impulseGO:005196920.011
monovalent inorganic cation transportGO:00156721280.011
negative regulation of synaptic transmissionGO:005080520.011
organ morphogenesisGO:00098871470.011
regulation of reactive oxygen species biosynthetic processGO:190342630.011
negative regulation of response to external stimulusGO:0032102830.011
positive regulation of acrosome reactionGO:200034440.011
endosomal transportGO:00161971290.011
Fly
protein autophosphorylationGO:00467771230.011
cell morphogenesis involved in differentiationGO:00009041440.011
regulation of stress activated protein kinase signaling cascadeGO:0070302850.011
response to oxygen levelsGO:00704821000.011
blood vessel morphogenesisGO:00485141620.011
regulation of phosphatase activityGO:0010921810.011
reproductive processGO:00224141060.011
organelle assemblyGO:00709251760.011
positive regulation of gtpase activityGO:00435471660.011
negative regulation of protein maturationGO:19033181420.011
neuron projection developmentGO:00311751060.011
camp metabolic processGO:0046058610.011
negative regulation of cellular component movementGO:00512711060.011
negative regulation of protein modification processGO:00314002000.011
response to axon injuryGO:004867810.011
ribonucleoside monophosphate metabolic processGO:00091611870.011
phototransductionGO:000760230.011
proteasomal protein catabolic processGO:00104981760.011
epidermis morphogenesisGO:004873030.011
nucleoside monophosphate metabolic processGO:00091231910.011
negative regulation of protein processingGO:00109551420.011
regulation of chemotaxisGO:0050920740.011
negative regulation of cell adhesionGO:0007162640.011
positive regulation of cell developmentGO:0010720920.011
regulation of exocytosisGO:0017157460.011
nucleoside monophosphate catabolic processGO:00091251590.011
protein ubiquitinationGO:00165673140.011
stem cell divisionGO:001714520.011
multicellular organismal homeostasisGO:0048871670.011
negative regulation of phosphorylationGO:00423261740.011
reactive nitrogen species metabolic processGO:200105730.011
protein import into nucleusGO:00066061040.011
i kappab kinase nf kappab signalingGO:00072491660.011
regulation of intracellular protein transportGO:00331571230.011
peptidyl serine phosphorylationGO:00181051010.011
monocarboxylic acid metabolic processGO:00327871850.011
neuron differentiationGO:00301821380.011
posttranscriptional regulation of gene expressionGO:00106082130.011
negative regulation of secretionGO:0051048580.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.010
tissue regenerationGO:004224630.010
cellular response to lipidGO:00713961270.010
regulation of body fluid levelsGO:0050878990.010
regulation of protein serine threonine kinase activityGO:00719001790.010
regulation of behaviorGO:0050795820.010
multicellular organismal signalingGO:0035637340.010
response to lipidGO:00339932060.010
regulation of meiotic cell cycleGO:005144540.010
negative regulation of proteolysisGO:00458611320.010
multicellular organismal response to stressGO:003355510.010
regulation of apoptotic signaling pathwayGO:20012331750.010
t cell activationGO:0042110990.010
cellular response to organonitrogen compoundGO:00714171240.010
ubiquitin dependent protein catabolic processGO:00065112060.010
rab protein signal transductionGO:003248240.010
cell chemotaxisGO:00603261120.010
dna repairGO:00062811980.010
positive regulation of synaptic transmissionGO:005080640.010
viral life cycleGO:00190581320.010
mitochondrion organizationGO:00070051560.010
striated muscle contractionGO:0006941520.010

SPTBN5 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.037
Human
sensory system diseaseDOID:00501552030.037
disease of metabolismDOID:00146672950.035
eye and adnexa diseaseDOID:14921500.034
eye diseaseDOID:56141490.032
central nervous system diseaseDOID:3311860.026
Human
inherited metabolic disorderDOID:6552420.026
retinal diseaseDOID:56791180.026
musculoskeletal system diseaseDOID:172230.019
disease of cellular proliferationDOID:145661740.016
cancerDOID:1621670.015
organ system cancerDOID:00506861640.015
connective tissue diseaseDOID:651090.012
retinal degenerationDOID:8466890.012
neurodegenerative diseaseDOID:12891020.011
Human
disease of mental healthDOID:150700.011
bone diseaseDOID:0080001880.011