Homo sapiens

94 known processes

PCNA

proliferating cell nuclear antigen

(Aliases: MGC8367)

PCNA biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna repairGO:00062811981.000
cellular response to dna damage stimulusGO:00069743791.000
double strand break repair via homologous recombinationGO:0000724500.999
meiosis iGO:000712740.999
double strand break repairGO:00063021010.998
postreplication repairGO:0006301120.997
dna recombinationGO:0006310770.997
dna replicationGO:00062601160.994
Fly
translesion synthesisGO:001998580.992
dna strand elongation involved in dna replicationGO:000627130.992
negative regulation of meiotic cell cycleGO:005144720.992
dna integrity checkpointGO:0031570710.988
mitotic dna integrity checkpointGO:0044774300.978
dna damage checkpointGO:0000077680.970
post embryonic developmentGO:000979120.968
chromatin modificationGO:00165682980.957
nucleotide excision repairGO:0006289310.955
leading strand elongationGO:000627210.939
base excision repairGO:0006284210.935
Mouse
dna biosynthetic processGO:0071897400.932
anatomical structure homeostasisGO:00602491000.908
apoptotic signaling pathwayGO:00971902680.905
mismatch repairGO:0006298150.900
mitotic g2 m transition checkpointGO:004481890.892
dna synthesis involved in dna repairGO:000073160.876
dna strand elongationGO:002261650.872
g2 dna damage checkpointGO:0031572260.864
vesicle mediated transportGO:00161923710.859
response to uvGO:0009411730.853
cell cycle checkpointGO:00000751170.800
mitotic cell cycleGO:00002783260.799
Fly
recombinational repairGO:0000725500.797
covalent chromatin modificationGO:00165692540.789
cellular amino acid metabolic processGO:00065201160.775
chromatin organizationGO:00063253510.765
negative regulation of dna metabolic processGO:0051053570.746
nucleotide biosynthetic processGO:00091651090.742
negative regulation of cell cycle phase transitionGO:1901988890.723
regulation of cell cycleGO:00517263930.717
nucleic acid phosphodiester bond hydrolysisGO:00903051020.716
dna dependent dna replicationGO:0006261440.669
chromatin remodelingGO:0006338550.666
mitotic dna damage checkpointGO:0044773280.560
negative regulation of mitotic cell cycle phase transitionGO:1901991850.556
response to radiationGO:00093141510.551
response to abiotic stimulusGO:00096283360.547
asymmetric stem cell divisionGO:009872210.542
regulation of cell cycle phase transitionGO:19019871260.537
mitotic g2 dna damage checkpointGO:000709570.535
cellular macromolecule catabolic processGO:00442653800.531
peptidyl lysine modificationGO:00182051440.525
reciprocal meiotic recombinationGO:000713140.510
chromatin silencingGO:0006342120.497
regulation of response to dna damage stimulusGO:2001020940.452
negative regulation of catalytic activityGO:00430863350.451
internal protein amino acid acetylationGO:00064751010.423
negative regulation of programmed cell deathGO:00430693210.423
negative regulation of gene expression epigeneticGO:0045814190.419
gene silencingGO:0016458490.411
regulation of gene expression epigeneticGO:0040029730.410
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.408
regulation of mitotic cell cycleGO:00073461890.402
negative regulation of cell cycleGO:00457861930.393
sex differentiationGO:0007548450.378
ribonucleoside biosynthetic processGO:0042455250.363
dna packagingGO:0006323770.355
positive regulation of cellular amino acid metabolic processGO:004576430.353
regulation of dna methylationGO:004403020.351
mitotic cell cycle phase transitionGO:00447721620.351
protein modification by small protein conjugationGO:00324463420.343
oxidation reduction processGO:00551143960.330
intrinsic apoptotic signaling pathwayGO:00971931270.324
regulation of cellular ketone metabolic processGO:0010565500.324
carbohydrate derivative biosynthetic processGO:19011372070.323
dna conformation changeGO:00711031130.304
embryo developmentGO:00097901230.300
glycosyl compound biosynthetic processGO:1901659270.299
negative regulation of apoptotic processGO:00430663160.283
regulation of cellular response to stressGO:00801352440.271
histone modificationGO:00165702510.269
regulation of dna repairGO:0006282470.265
response to oxygen containing compoundGO:19017003690.263
response to metal ionGO:0010038840.256
negative regulation of mitotic cell cycleGO:00459301020.241
double strand break repair via nonhomologous end joiningGO:0006303100.235
leukocyte mediated immunityGO:0002443590.228
regenerationGO:003109940.228
response to light stimulusGO:0009416870.224
meiotic cell cycle processGO:190304680.222
positive regulation of transportGO:00510503360.216
regulation of transferase activityGO:00513383550.203
regulation of cellular amino acid metabolic processGO:000652160.201
cellular response to external stimulusGO:00714961110.201
mrna metabolic processGO:00160711750.191
dna double strand break processingGO:0000729100.190
regulation of dna metabolic processGO:00510521530.190
negative regulation of cell deathGO:00605483450.190
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.188
Mouse
nucleoside monophosphate metabolic processGO:00091231910.176
gonad developmentGO:0008406340.173
nucleoside monophosphate catabolic processGO:00091251590.173
protein monoubiquitinationGO:0006513390.164
amine metabolic processGO:0009308440.162
protein alkylationGO:0008213740.161
cellular amine metabolic processGO:0044106410.160
purine nucleotide biosynthetic processGO:0006164840.159
negative regulation of g1 s transition of mitotic cell cycleGO:2000134290.156
cell cycle phase transitionGO:00447701730.154
nuclear transportGO:00511691790.153
regulation of double strand break repair via homologous recombinationGO:0010569110.152
chromatin assemblyGO:0031497610.151
internal peptidyl lysine acetylationGO:0018393970.150
embryo development ending in birth or egg hatchingGO:0009792340.150
telomere maintenanceGO:0000723320.146
cellular macromolecular complex assemblyGO:00346223240.145
determination of adult lifespanGO:000834020.143
dna catabolic processGO:0006308490.139
negative regulation of cell cycle processGO:00109481210.138
positive regulation of cellular amine metabolic processGO:003324070.138
regulation of dna replicationGO:0006275680.134
ribonucleoside catabolic processGO:00424544060.129
non recombinational repairGO:0000726140.128
regulation of double strand break repairGO:2000779220.125
rna interferenceGO:001624640.124
single organism reproductive processGO:0044702980.123
purine ribonucleoside triphosphate metabolic processGO:00092054110.122
meiotic nuclear divisionGO:0007126100.121
development of primary sexual characteristicsGO:0045137350.119
regulation of mitotic cell cycle phase transitionGO:19019901180.115
response to ionizing radiationGO:0010212650.113
atp dependent chromatin remodelingGO:0043044250.113
regulation of peptidase activityGO:00525471800.109
protein dna complex assemblyGO:0065004640.108
protein acetylationGO:00064731160.107
regulation of chromatin organizationGO:1902275560.107
response to inorganic substanceGO:00100351270.106
reproductive processGO:00224141060.105
response to purine containing compoundGO:0014074400.102
regulation of meiotic cell cycleGO:005144540.101
cellular protein complex assemblyGO:00436231880.101
purine nucleoside triphosphate metabolic processGO:00091444120.099
generation of precursor metabolites and energyGO:0006091680.095
somatic diversification of immune receptors via somatic mutationGO:000256610.093
extrinsic apoptotic signaling pathwayGO:00971911190.092
oocyte maturationGO:000155610.092
mrna processingGO:00063971330.091
nervous system developmentGO:00073992930.091
Fly
reproductionGO:0000003630.089
response to steroid hormoneGO:0048545800.087
alpha amino acid metabolic processGO:1901605720.086
posttranscriptional regulation of gene expressionGO:00106082130.085
single organism carbohydrate metabolic processGO:00447231930.083
response to hormoneGO:00097251750.083
glycosyl compound catabolic processGO:19016584130.082
purine ribonucleoside monophosphate metabolic processGO:00091671860.081
meiotic cell cycleGO:0051321130.080
cellular response to ionizing radiationGO:0071479320.078
regulation of apoptotic signaling pathwayGO:20012331750.076
receptor mediated endocytosisGO:0006898840.076
peptidyl serine phosphorylationGO:00181051010.074
regulation of bindingGO:00510981110.072
immune effector processGO:00022521590.069
development of primary male sexual characteristicsGO:0046546230.068
negative regulation of phosphorus metabolic processGO:00105632670.067
purine nucleoside monophosphate metabolic processGO:00091261860.066
regulation of establishment of protein localizationGO:00702012420.065
protein ubiquitinationGO:00165673140.065
ribonucleoside triphosphate metabolic processGO:00091994120.063
developmental process involved in reproductionGO:0003006660.063
response to lipidGO:00339932060.063
methylationGO:00322591060.062
somatic hypermutation of immunoglobulin genesGO:001644610.062
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediatorGO:0042771230.059
cellular response to organic cyclic compoundGO:00714071270.058
hemopoiesisGO:00300971800.057
ribonucleotide catabolic processGO:00092614050.057
regulation of chromatin modificationGO:1903308510.056
atp metabolic processGO:00460341760.056
posttranscriptional gene silencing by rnaGO:0035194250.054
response to organic cyclic compoundGO:00140702040.053
atp catabolic processGO:00062001570.053
mitotic cell cycle checkpointGO:0007093680.053
anion transportGO:00068201610.052
response to other organismGO:00517072610.051
Zebrafish Fly
nucleoside catabolic processGO:00091644080.051
response to alcoholGO:0097305640.049
positive regulation of developmental processGO:00510943140.048
gene conversionGO:003582210.048
multi organism cellular processGO:00447641560.047
negative regulation of apoptotic signaling pathwayGO:2001234970.046
regulation of nucleotide metabolic processGO:00061402690.046
cellular response to acid chemicalGO:0071229440.046
viral processGO:00160321460.044
interstrand cross link repairGO:003629730.043
spermatid developmentGO:000728640.042
purine ribonucleoside monophosphate biosynthetic processGO:0009168160.042
positive regulation of dna templated transcription elongationGO:0032786180.042
peptidyl lysine acetylationGO:00183941010.042
purine containing compound biosynthetic processGO:0072522880.041
cellular response to oxidative stressGO:0034599850.041
telomere organizationGO:0032200330.039
cell projection organizationGO:00300302520.038
multicellular organismal agingGO:001025930.038
histone acetylationGO:0016573930.037
regulation of gene silencingGO:0060968240.037
lymphocyte proliferationGO:0046651700.037
mature ribosome assemblyGO:004225650.036
secretionGO:00469032540.036
cellular ketone metabolic processGO:0042180800.036
nitrogen compound transportGO:00717051910.036
mitotic sister chromatid segregationGO:0000070530.035
positive regulation of programmed cell deathGO:00430682490.035
chordate embryonic developmentGO:0043009340.035
response to virusGO:00096151260.035
nucleobase biosynthetic processGO:004611240.035
ribonucleotide biosynthetic processGO:0009260810.035
negative regulation of phosphate metabolic processGO:00459362670.035
signal transduction by p53 class mediatorGO:0072331720.034
chromosome condensationGO:0030261150.034
negative regulation of hydrolase activityGO:00513461820.034
cellular component morphogenesisGO:00329893140.034
regulation of meiosisGO:004002030.034
signal transduction in response to dna damageGO:0042770570.034
response to transforming growth factor betaGO:0071559940.033
male meiosisGO:000714010.033
regulation of histone modificationGO:0031056470.032
dephosphorylationGO:00163112090.032
cellular response to endogenous stimulusGO:00714953360.032
organophosphate biosynthetic processGO:00904071630.032
purine nucleoside triphosphate catabolic processGO:00091463920.031
adaptive immune responseGO:0002250490.031
carbohydrate metabolic processGO:00059752070.031
regulation of cell cycle processGO:00105642660.031
response to hypoxiaGO:0001666960.031
somatic diversification of immune receptorsGO:000220080.031
negative regulation of intracellular signal transductionGO:19025321830.030
sister chromatid cohesionGO:0007062240.030
positive regulation of bindingGO:0051099450.029
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332370.028
negative regulation of chromatin modificationGO:1903309210.028
chemical homeostasisGO:00488783060.028
immune system developmentGO:00025201950.028
chromosome segregationGO:00070591140.027
interspecies interaction between organismsGO:00444191560.026
cellular response to organonitrogen compoundGO:00714171240.026
regulation of cellular amine metabolic processGO:0033238110.026
behaviorGO:00076101120.025
pancreas developmentGO:0031016190.025
response to estrogenGO:0043627470.025
mitotic cell cycle processGO:19030472860.025
Fly
regulation of viral processGO:00507921030.024
sex determinationGO:000753030.024
organ morphogenesisGO:00098871470.024
regulation of g1 s transition of mitotic cell cycleGO:2000045400.024
response to reactive oxygen speciesGO:0000302610.024
ribosome assemblyGO:004225590.024
nucleoside phosphate catabolic processGO:19012924120.024
cell cycle g1 s phase transitionGO:0044843800.023
protein acylationGO:00435431380.023
regulation of kinase activityGO:00435493140.022
protein dna complex subunit organizationGO:0071824800.022
circulatory system developmentGO:00723592620.022
immune responseGO:00069553070.022
Fly
epithelial cell differentiationGO:00308551410.022
nucleosome organizationGO:0034728660.022
dna damage response signal transduction by p53 class mediatorGO:0030330440.022
response to extracellular stimulusGO:0009991850.021
blastocyst developmentGO:000182430.021
agingGO:0007568660.021
regulation of intracellular transportGO:00323861950.021
regulation of chromatin silencingGO:003193580.021
regulation of chromosome organizationGO:00330441030.021
symbiosis encompassing mutualism through parasitismGO:00444031560.020
purine nucleoside biosynthetic processGO:0042451230.020
positive regulation of growthGO:0045927580.020
regulation of phosphatase activityGO:0010921810.020
cellular response to oxygen containing compoundGO:19017012760.020
somatic recombination of immunoglobulin genes involved in immune responseGO:000220430.020
positive regulation of immune system processGO:00026842830.020
polynucleotide dephosphorylationGO:009850130.020
ribonucleoside monophosphate metabolic processGO:00091611870.019
urate metabolic processGO:0046415110.019
negative regulation of cell cycle g1 s phase transitionGO:1902807290.019
meiotic chromosome segregationGO:004513240.019
regulation of protein kinase activityGO:00458592890.019
v d j recombinationGO:003315130.019
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.019
negative regulation of double strand break repair via nonhomologous end joiningGO:200103310.019
meiotic chromosome separationGO:005130730.019
response to caffeineGO:003100030.019
negative regulation of dephosphorylationGO:0035305630.019
reproductive system developmentGO:0061458560.019
regulation of endopeptidase activityGO:00525481700.018
positive regulation of cell proliferationGO:00082843010.018
histone lysine methylationGO:0034968500.018
regulation of cell cycle g1 s phase transitionGO:1902806420.018
mrna 3 end processingGO:0031124240.017
ras protein signal transductionGO:0007265730.017
organophosphate catabolic processGO:00464344300.017
positive regulation of protein transportGO:00512221350.017
muscle contractionGO:0006936730.017
lagging strand elongationGO:000627330.017
carboxylic acid biosynthetic processGO:0046394970.017
rna catabolic processGO:0006401710.016
cell fate commitmentGO:0045165270.016
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.016
response to oxidative stressGO:00069791210.016
organic acid biosynthetic processGO:0016053970.016
maintenance of dna repeat elementsGO:004357040.016
myosin filament organizationGO:003103320.016
regulation of histone methylationGO:0031060160.015
nucleotide catabolic processGO:00091664080.015
nucleoside biosynthetic processGO:0009163260.015
dna modificationGO:0006304270.015
cellular response to reactive oxygen speciesGO:0034614500.015
retina development in camera type eyeGO:0060041150.015
regulation of growthGO:00400081650.015
positive regulation of dna metabolic processGO:0051054730.015
cell part morphogenesisGO:00329901370.015
macromolecule methylationGO:0043414970.015
multi organism reproductive processGO:0044703540.015
cellular response to hormone stimulusGO:00328701250.015
lymphocyte activationGO:00466491330.014
neuron developmentGO:00486661130.014
neurogenesisGO:00220081690.014
Fly
negative regulation of transferase activityGO:00513481240.014
cellular response to alcoholGO:0097306290.013
mitotic g1 dna damage checkpointGO:0031571170.013
positive regulation of intracellular transportGO:00323881040.013
small molecule biosynthetic processGO:00442831570.013
regulation of protein serine threonine kinase activityGO:00719001790.013
single organism carbohydrate catabolic processGO:0044724330.013
ribonucleoside monophosphate catabolic processGO:00091581580.013
mononuclear cell proliferationGO:0032943710.013
hexose metabolic processGO:0019318550.013
endocytosisGO:00068971590.013
isotype switchingGO:004519030.012
proteolysis involved in cellular protein catabolic processGO:00516032440.012
response to transition metal nanoparticleGO:1990267290.012
regulation of glucose metabolic processGO:0010906280.012
positive regulation of helicase activityGO:005109660.012
viral life cycleGO:00190581320.012
regulation of cysteine type endopeptidase activityGO:20001161270.012
purine ribonucleotide biosynthetic processGO:0009152790.012
growthGO:00400072020.012
histone exchangeGO:004348630.012
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.012
response to decreased oxygen levelsGO:0036293960.011
regulation of developmental growthGO:0048638300.011
histone methylationGO:0016571600.011
dna templated transcription elongationGO:0006354250.011
eye developmentGO:0001654420.011
organonitrogen compound biosynthetic processGO:19015662000.011
regulation of intracellular protein transportGO:00331571230.011
neutral lipid catabolic processGO:0046461120.011
positive regulation of histone modificationGO:0031058290.011
regulation of dephosphorylationGO:0035303960.011
reproductive structure developmentGO:0048608550.010
purine ribonucleoside biosynthetic processGO:0046129230.010
cellular modified amino acid metabolic processGO:0006575640.010

PCNA disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:29141550.125
hematopoietic system diseaseDOID:741000.125
disease of metabolismDOID:00146672950.097