Homo sapiens

103 known processes

SAMHD1

SAM domain and HD domain 1

(Aliases: DCIP,HDDC1,SBBI88,MOP-5)

SAMHD1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to bacterial lipoproteinGO:007122030.848
growth of symbiont in hostGO:004411710.322
positive regulation of toll like receptor 2 signaling pathwayGO:003413720.271
positive regulation of toll like receptor 4 signaling pathwayGO:003414560.259
growth of symbiont involved in interaction with hostGO:004411620.209
organophosphate catabolic processGO:00464344300.175
regulation of locomotionGO:00400123290.164
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.155
symbiosis encompassing mutualism through parasitismGO:00444031560.154
purine ribonucleotide catabolic processGO:00091544040.150
purine nucleotide catabolic processGO:00061954050.141
nucleoside triphosphate metabolic processGO:00091414220.136
nucleotide catabolic processGO:00091664080.135
purine nucleoside triphosphate catabolic processGO:00091463920.128
interspecies interaction between organismsGO:00444191560.128
regulation of toll like receptor 2 signaling pathwayGO:003413520.126
immune effector processGO:00022521590.124
purine containing compound catabolic processGO:00725234110.124
positive regulation of toll like receptor signaling pathwayGO:0034123100.123
purine nucleoside triphosphate metabolic processGO:00091444120.123
nucleoside phosphate catabolic processGO:19012924120.121
purine ribonucleoside metabolic processGO:00461284370.119
ribonucleoside triphosphate catabolic processGO:00092033910.118
myeloid cell differentiationGO:00300991170.114
nucleoside triphosphate catabolic processGO:00091433940.111
response to bacterial lipopeptideGO:007033930.107
purine ribonucleoside catabolic processGO:00461303980.104
purine nucleoside catabolic processGO:00061523980.103
modulation of growth of symbiont involved in interaction with hostGO:004414420.101
nucleoside catabolic processGO:00091644080.101
ribonucleoside catabolic processGO:00424544060.089
hematopoietic or lymphoid organ developmentGO:00485341860.089
immune responseGO:00069553070.087
ribonucleoside triphosphate metabolic processGO:00091994120.086
regulation of cell motilityGO:20001452990.086
regulation of growth of symbiont in hostGO:004412610.086
purine ribonucleoside triphosphate catabolic processGO:00092073910.084
positive regulation of behaviorGO:0048520600.078
ribonucleotide catabolic processGO:00092614050.078
negative regulation of growth of symbiont in hostGO:004413010.074
negative regulation of growth of symbiont involved in interaction with hostGO:004414620.071
response to cytokineGO:00340972320.071
cellular response to bacterial lipopeptideGO:007122130.071
regulation of cell migrationGO:00303342890.071
positive regulation of locomotionGO:00400171860.069
negative regulation of multi organism processGO:0043901920.065
glycosyl compound catabolic processGO:19016584130.061
purine ribonucleoside triphosphate metabolic processGO:00092054110.060
gtp catabolic processGO:00061842370.060
positive regulation of toll like receptor 3 signaling pathwayGO:003414110.060
cell chemotaxisGO:00603261120.059
response to oxygen containing compoundGO:19017003690.056
response to other organismGO:00517072610.056
positive regulation of cellular component movementGO:00512721810.053
growth involved in symbiotic interactionGO:004411020.053
defense responseGO:00069523150.053
cellular response to lipoteichoic acidGO:007122330.050
guanosine containing compound catabolic processGO:19010692390.050
hemopoiesisGO:00300971800.050
positive regulation of nucleotide catabolic processGO:00308131850.050
multicellular organismal agingGO:001025930.049
response to fungusGO:000962040.049
circadian behaviorGO:004851220.048
cellular amino acid metabolic processGO:00065201160.048
response to lipoteichoic acidGO:007039130.048
regulation of cellular component movementGO:00512703340.047
regulation of nucleotide metabolic processGO:00061402690.047
cellular response to oxygen containing compoundGO:19017012760.046
positive regulation of response to external stimulusGO:0032103880.045
immune system developmentGO:00025201950.045
regulation of nucleotide catabolic processGO:00308112050.045
chemokine c x c motif ligand 2 productionGO:007256730.044
regulation of anatomical structure morphogenesisGO:00226032860.044
guanosine containing compound metabolic processGO:19010682440.042
regulation of purine nucleotide metabolic processGO:19005422640.042
positive regulation of leukocyte chemotaxisGO:0002690380.042
cation transportGO:00068123310.042
organonitrogen compound biosynthetic processGO:19015662000.041
defense response to fungusGO:005083240.041
proteolysis involved in cellular protein catabolic processGO:00516032440.041
viral processGO:00160321460.041
defense response to other organismGO:00985421290.041
regulation of viral processGO:00507921030.040
determination of adult lifespanGO:000834020.039
regulation of multi organism processGO:00439001570.039
purine nucleotide biosynthetic processGO:0006164840.038
gtp metabolic processGO:00460392390.038
response to external biotic stimulusGO:00432072610.037
regulation of nucleoside metabolic processGO:00091182090.037
positive regulation of purine nucleotide metabolic processGO:19005442270.036
chemotaxisGO:00069351570.036
protein catabolic processGO:00301633250.036
response to bacterial lipoproteinGO:003249330.036
taxisGO:00423301570.036
toll like receptor 2 signaling pathwayGO:003413440.036
organophosphate biosynthetic processGO:00904071630.035
positive regulation of nucleotide metabolic processGO:00459812300.034
positive regulation of hydrolase activityGO:00513453310.034
cytoplasmic transportGO:00164823790.033
regulation of transferase activityGO:00513383550.033
regulation of purine nucleotide catabolic processGO:00331212050.033
ion homeostasisGO:00508012300.032
locomotory behaviorGO:000762610.031
negative regulation of growthGO:0045926970.031
vesicle mediated transportGO:00161923710.031
regulation of intracellular transportGO:00323861950.031
positive regulation of cell motilityGO:20001471770.031
chemical homeostasisGO:00488783060.031
cytokine productionGO:00018162470.030
positive regulation of immune system processGO:00026842830.030
post embryonic developmentGO:000979120.030
regulation of lymphocyte activationGO:00512491030.029
membrane organizationGO:00610242920.029
i kappab kinase nf kappab signalingGO:00072491660.029
positive regulation of cellular component organizationGO:00511303760.028
leukocyte chemotaxisGO:0030595760.028
positive regulation of cellular catabolic processGO:00313312840.028
growthGO:00400072020.028
positive regulation of nucleoside metabolic processGO:00459791860.028
cellular protein catabolic processGO:00442572610.028
regulation of growthGO:00400081650.027
protein ubiquitinationGO:00165673140.027
positive regulation of purine nucleotide catabolic processGO:00331231850.026
single organism membrane organizationGO:00448022680.026
response to bacteriumGO:00096171440.026
regulation of cellular component biogenesisGO:00440872810.026
regulation of behaviorGO:0050795820.026
regulation of proteolysisGO:00301622930.026
response to virusGO:00096151260.026
cellular component morphogenesisGO:00329893140.026
negative regulation of multicellular organismal processGO:00512413170.026
carbohydrate derivative biosynthetic processGO:19011372070.025
cellular lipid metabolic processGO:00442553030.025
rhythmic behaviorGO:000762220.025
positive regulation of cell migrationGO:00303351720.025
negative regulation of cellular protein metabolic processGO:00322693530.024
cell morphogenesisGO:00009022960.024
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.024
regulation of i kappab kinase nf kappab signalingGO:00431221620.024
rho protein signal transductionGO:0007266260.024
posttranscriptional regulation of gene expressionGO:00106082130.023
response to biotic stimulusGO:00096072760.023
positive regulation of chemotaxisGO:0050921570.023
cellular macromolecule catabolic processGO:00442653800.023
viral life cycleGO:00190581320.023
ras protein signal transductionGO:0007265730.023
response to lipidGO:00339932060.023
cellular response to dna damage stimulusGO:00069743790.023
amine metabolic processGO:0009308440.023
regulation of gtp catabolic processGO:00331241800.023
cytokine mediated signaling pathwayGO:00192211090.022
protein maturationGO:00516042330.022
regulation of kinase activityGO:00435493140.022
negative regulation of protein metabolic processGO:00512483910.022
regulation of cellular amino acid metabolic processGO:000652160.022
positive regulation of leukocyte migrationGO:0002687460.022
positive regulation of phosphorylationGO:00423273940.022
regulation of response to external stimulusGO:00321012220.021
nuclear transportGO:00511691790.021
regulation of protein bindingGO:0043393660.021
negative regulation of transportGO:00510511760.021
negative regulation of phosphate metabolic processGO:00459362670.021
regulation of gtpase activityGO:00430871800.021
negative regulation of cell proliferationGO:00082852280.020
response to abiotic stimulusGO:00096283360.020
interleukin 17 productionGO:0032620120.020
regulation of chemokine productionGO:0032642310.020
regulation of cellular response to stressGO:00801352440.020
positive regulation of cellular amino acid metabolic processGO:004576430.020
chemokine biosynthetic processGO:004203340.020
response to molecule of bacterial originGO:0002237820.020
regulation of neutrophil migrationGO:1902622100.020
regulation of cellular amine metabolic processGO:0033238110.020
cellular response to endogenous stimulusGO:00714953360.020
protein processingGO:00164852260.020
cellular cation homeostasisGO:00300031630.020
positive regulation of interleukin 8 productionGO:0032757360.020
negative regulation of catalytic activityGO:00430863350.020
regulation of bindingGO:00510981110.019
toll like receptor 4 signaling pathwayGO:0034142120.019
behaviorGO:00076101120.019
positive regulation of catabolic processGO:00098963100.019
sequestering of metal ionGO:0051238240.019
multi organism cellular processGO:00447641560.019
protein localization to organelleGO:00333652800.019
purine ribonucleoside monophosphate metabolic processGO:00091671860.019
ribonucleoside monophosphate metabolic processGO:00091611870.019
divalent metal ion transportGO:00708381520.019
neutrophil chemotaxisGO:0030593240.019
innate immune responseGO:00450871780.019
atp metabolic processGO:00460341760.019
chromatin organizationGO:00063253510.019
regulation of leukocyte chemotaxisGO:0002688460.019
positive regulation of gtpase activityGO:00435471660.018
protein autophosphorylationGO:00467771230.018
cellular response to molecule of bacterial originGO:0071219620.018
regulation of chemotaxisGO:0050920740.018
cellular amine metabolic processGO:0044106410.018
metal ion homeostasisGO:00550651690.018
positive regulation of cell proliferationGO:00082843010.018
mrna stabilizationGO:0048255180.018
segmentationGO:003528240.017
cellular chemical homeostasisGO:00550821800.017
granulocyte migrationGO:0097530400.017
regulation of chemokine c x c motif ligand 2 productionGO:200034120.017
protein modification by small protein conjugationGO:00324463420.017
single organism carbohydrate metabolic processGO:00447231930.017
rna stabilizationGO:0043489180.017
leukocyte proliferationGO:0070661740.017
regulation of cytoplasmic transportGO:19036491490.017
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.017
myeloid leukocyte migrationGO:0097529620.017
compound eye developmentGO:004874910.017
purine nucleoside monophosphate metabolic processGO:00091261860.017
regulation of protein kinase activityGO:00458592890.017
regulation of protein transportGO:00512232130.017
regulation of mapk cascadeGO:00434082620.017
system processGO:00030083490.016
positive regulation of protein kinase activityGO:00458601900.016
small gtpase mediated signal transductionGO:0007264780.016
cellular response to lipidGO:00713961270.016
leukocyte activationGO:00453211640.016
intracellular protein transportGO:00068862700.016
leukocyte migrationGO:00509001070.016
regulation of leukocyte migrationGO:0002685630.016
positive regulation of apoptotic processGO:00430652460.016
actin filament based processGO:00300292240.016
positive regulation of cytokine productionGO:00018191670.016
mitotic cell cycle processGO:19030472860.016
defense response to virusGO:0051607710.016
regulation of cytoskeleton organizationGO:00514931770.016
cell activationGO:00017752130.016
purine ribonucleoside monophosphate catabolic processGO:00091691580.016
regulation of granulocyte chemotaxisGO:0071622160.016
anatomical structure formation involved in morphogenesisGO:00486462840.015
regulation of interleukin 17 productionGO:0032660120.015
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557220.015
protein targetingGO:00066051870.015
regulation of cell morphogenesisGO:00226041530.015
regulation of endopeptidase activityGO:00525481700.015
regulation of protein complex assemblyGO:00432541470.015
cellular ketone metabolic processGO:0042180800.015
protein oligomerizationGO:00512591730.015
erk1 and erk2 cascadeGO:00703711040.015
regulation of body fluid levelsGO:0050878990.015
negative regulation of cell deathGO:00605483450.015
carbohydrate metabolic processGO:00059752070.015
regulation of vasculature developmentGO:1901342970.015
positive regulation of leukocyte activationGO:0002696800.015
positive regulation of interleukin 23 productionGO:003274740.015
regulation of leukocyte activationGO:00026941150.015
regulation of toll like receptor 3 signaling pathwayGO:003413920.015
ubiquitin dependent protein catabolic processGO:00065112060.015
regulation of small gtpase mediated signal transductionGO:00510561560.015
negative regulation of cell motilityGO:20001461040.015
plasma membrane organizationGO:00070091150.015
regulation of cell differentiationGO:00455953930.015
positive regulation of ras gtpase activityGO:00323201170.015
cellular response to triacyl bacterial lipopeptideGO:007172720.014
mitotic cell cycleGO:00002783260.014
ribonucleoside monophosphate catabolic processGO:00091581580.014
regulation of cellular ketone metabolic processGO:0010565500.014
sulfur compound metabolic processGO:00067901010.014
female gamete generationGO:000729220.014
transmembrane transportGO:00550853990.014
nucleoside monophosphate catabolic processGO:00091251590.014
regulation of synaptic plasticityGO:004816730.014
peripheral nervous system developmentGO:000742220.014
negative regulation of hydrolase activityGO:00513461820.014
cellular macromolecular complex assemblyGO:00346223240.014
response to oxygen levelsGO:00704821000.014
spermatid developmentGO:000728640.014
protein homooligomerizationGO:00512601000.014
positive regulation of stress activated mapk cascadeGO:0032874600.014
oogenesisGO:004847720.014
regulation of leukocyte proliferationGO:0070663670.014
regulation of cell cycle processGO:00105642660.014
negative regulation of phosphorus metabolic processGO:00105632670.014
response to woundingGO:00096111680.014
regulation of stress activated protein kinase signaling cascadeGO:0070302850.014
positive regulation of nf kappab transcription factor activityGO:0051092810.014
atp catabolic processGO:00062001570.014
cellular homeostasisGO:00197251960.014
positive regulation of proteolysisGO:00458621420.014
regulation of ras gtpase activityGO:00323181280.014
positive regulation of chemokine productionGO:0032722220.014
negative regulation of cell cycleGO:00457861930.014
actin cytoskeleton organizationGO:00300362070.014
cell projection organizationGO:00300302520.014
inflammatory responseGO:0006954790.013
cardiovascular system developmentGO:00723582620.013
signal transduction by phosphorylationGO:00230142970.013
calcium ion transportGO:00068161470.013
endomembrane system organizationGO:00102561960.013
regulation of defense responseGO:00313471540.013
cell substrate adhesionGO:00315891320.013
regulation of peptidase activityGO:00525471800.013
positive regulation of transportGO:00510503360.013
regulation of establishment of protein localizationGO:00702012420.013
cellular response to biotic stimulusGO:0071216710.013
cellular protein complex assemblyGO:00436231880.013
divalent inorganic cation transportGO:00725111580.013
activation of protein kinase activityGO:0032147900.013
response to hormoneGO:00097251750.013
regulation of cell developmentGO:00602841610.013
regulation of homeostatic processGO:00328441210.013
positive regulation of developmental processGO:00510943140.013
neuroblast proliferationGO:000740540.013
regulation of apoptotic signaling pathwayGO:20012331750.013
sequestering of calcium ionGO:0051208170.013
nervous system developmentGO:00073992930.013
response to organonitrogen compoundGO:00102431560.013
memoryGO:000761330.013
ameboidal type cell migrationGO:00016671350.013
regulation of metal ion transportGO:00109591200.013
purine ribonucleotide biosynthetic processGO:0009152790.012
regulation of protein serine threonine kinase activityGO:00719001790.012
divalent inorganic cation homeostasisGO:00725071360.012
negative regulation of programmed cell deathGO:00430693210.012
cell growthGO:00160491600.012
regenerationGO:003109940.012
mapk cascadeGO:00001652880.012
positive regulation of immune responseGO:00507781590.012
regulation of membrane potentialGO:0042391950.012
blastoderm segmentationGO:000735020.012
cellular ion homeostasisGO:00068731680.012
epithelium developmentGO:00604292270.012
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
regulation of interleukin 6 productionGO:0032675370.012
regulation of chemokine biosynthetic processGO:004507340.012
neurotransmitter secretionGO:000726940.012
regulation of protein processingGO:00706131500.012
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555440.012
regulation of actin filament based processGO:00329701410.012
regulation of rna stabilityGO:0043487230.012
positive regulation of tumor necrosis factor productionGO:0032760210.012
modification dependent protein catabolic processGO:00199412090.012
regulation of protein localizationGO:00328802960.012
circulatory system developmentGO:00723592620.012
cell part morphogenesisGO:00329901370.012
neuromuscular junction developmentGO:000752830.012
protein importGO:00170381300.012
interleukin 8 productionGO:0032637510.012
spermatid differentiationGO:004851540.012
apoptotic signaling pathwayGO:00971902680.012
positive regulation of gtp catabolic processGO:00331261660.012
nucleotide biosynthetic processGO:00091651090.012
positive regulation of innate immune responseGO:0045089790.012
modification dependent macromolecule catabolic processGO:00436322120.012
cell projection morphogenesisGO:00488581290.012
negative regulation of cellular component organizationGO:00511292350.012
regulation of erk1 and erk2 cascadeGO:0070372990.012
cell developmentGO:00484683280.012
secretion by cellGO:00329402260.012
lipid metabolic processGO:00066293810.011
positive regulation of interleukin 6 productionGO:0032755210.011
positive regulation of leukocyte proliferationGO:0070665480.011
peptidyl tyrosine phosphorylationGO:00181081700.011
response to radiationGO:00093141510.011
chemokine productionGO:0032602320.011
regulation of vesicle mediated transportGO:00606271300.011
positive regulation of programmed cell deathGO:00430682490.011
regulation of cysteine type endopeptidase activityGO:20001161270.011
regulation of cyclic nucleotide metabolic processGO:0030799630.011
regulation of cytokine productionGO:00018172320.011
response to oxidative stressGO:00069791210.011
rna interferenceGO:001624640.011
defense response to gram positive bacteriumGO:0050830290.011
negative regulation of protein maturationGO:19033181420.011
response to organic cyclic compoundGO:00140702040.011
regulation of protein maturationGO:19033171500.011
stress activated protein kinase signaling cascadeGO:0031098940.011
histone modificationGO:00165702510.011
negative regulation of catabolic processGO:00098951040.011
nucleoside monophosphate metabolic processGO:00091231910.011
interleukin 6 productionGO:0032635370.011
positive regulation of bindingGO:0051099450.011
biological adhesionGO:00226103310.011
immune response activating signal transductionGO:0002757900.011
establishment of protein localization to membraneGO:00901501210.011
maintenance of locationGO:00512351120.011
3 utr mediated mrna stabilizationGO:007093580.011
viral genome replicationGO:0019079500.011
positive regulation of transferase activityGO:00513472270.011
inner ear morphogenesisGO:004247240.011
t cell differentiation in thymusGO:003307740.010
positive regulation of cell activationGO:0050867810.010
purine nucleoside monophosphate catabolic processGO:00091281580.010
angiogenesisGO:00015251470.010
visual behaviorGO:000763220.010
purine containing compound biosynthetic processGO:0072522880.010
protein localization to membraneGO:00726571600.010
negative regulation of immune system processGO:00026831360.010
negative regulation of viral genome replicationGO:0045071350.010
nitrogen compound transportGO:00717051910.010
response to triacyl bacterial lipopeptideGO:007172520.010
phospholipid metabolic processGO:0006644990.010
central nervous system developmentGO:00074171230.010
negative regulation of cellular amino acid metabolic processGO:004576320.010
positive regulation of erk1 and erk2 cascadeGO:0070374750.010
response to tumor necrosis factorGO:0034612760.010
positive regulation of cellular component biogenesisGO:00440891580.010
regulation of mononuclear cell proliferationGO:0032944650.010
generation of neuronsGO:00486991520.010
endosomal transportGO:00161971290.010
positive regulation of cell differentiationGO:00455972110.010
negative regulation of proteolysisGO:00458611320.010
chromatin modificationGO:00165682980.010
toll signaling pathwayGO:000806320.010
negative regulation of protein transportGO:0051224750.010
stress activated mapk cascadeGO:0051403930.010
nucleoside phosphate biosynthetic processGO:19012931090.010

SAMHD1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease by infectious agentDOID:0050117340.105
parasitic infectious diseaseDOID:1398160.040
musculoskeletal system diseaseDOID:172230.030
organ system cancerDOID:00506861640.026
disease of cellular proliferationDOID:145661740.026
cancerDOID:1621670.026
parasitic protozoa infectious diseaseDOID:2789160.024
immune system diseaseDOID:29141550.018
nervous system diseaseDOID:8634310.017
sensory system diseaseDOID:00501552030.017
eye diseaseDOID:56141490.016
eye and adnexa diseaseDOID:14921500.016
disease of metabolismDOID:00146672950.013
central nervous system diseaseDOID:3311860.012
connective tissue diseaseDOID:651090.011
bone diseaseDOID:0080001880.010
aicardi goutieres syndromeDOID:005062970.001