Homo sapiens

49 known processes

RPA1

replication protein A1, 70kDa

(Aliases: HSSB,RF-A,RP-A,REPA1,MST075,RPA70)

RPA1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna dependent dna replicationGO:0006261441.000
Yeast Fly
meiosis iGO:000712741.000
Yeast
double strand break repairGO:00063021011.000
base excision repairGO:0006284211.000
cellular response to dna damage stimulusGO:00069743791.000
nucleotide excision repairGO:0006289311.000
reciprocal meiotic recombinationGO:000713141.000
Yeast
purine nucleoside monophosphate catabolic processGO:00091281580.999
telomere maintenance via telomeraseGO:000700480.999
Yeast
dna conformation changeGO:00711031130.998
Yeast
regulation of double strand break repair via homologous recombinationGO:0010569110.996
dna repairGO:00062811980.996
purine ribonucleoside monophosphate metabolic processGO:00091671860.996
dna recombinationGO:0006310770.996
double strand break repair via homologous recombinationGO:0000724500.995
mismatch repairGO:0006298150.995
dna strand elongation involved in dna replicationGO:000627130.994
ribonucleoside monophosphate metabolic processGO:00091611870.991
nucleoside triphosphate catabolic processGO:00091433940.991
regulation of mitotic cell cycleGO:00073461890.990
Fly
recombinational repairGO:0000725500.989
reciprocal dna recombinationGO:003582540.988
Yeast
leading strand elongationGO:000627210.987
dna unwinding involved in dna replicationGO:000626820.986
Yeast
ribonucleoside monophosphate catabolic processGO:00091581580.986
dna duplex unwindingGO:0032508300.984
Yeast
nucleoside monophosphate metabolic processGO:00091231910.984
non recombinational repairGO:0000726140.980
atp metabolic processGO:00460341760.973
purine nucleoside triphosphate catabolic processGO:00091463920.968
glycosyl compound catabolic processGO:19016584130.967
dna replicationGO:00062601160.962
nucleoside monophosphate catabolic processGO:00091251590.962
purine ribonucleoside monophosphate catabolic processGO:00091691580.962
purine ribonucleoside catabolic processGO:00461303980.959
mitotic cell cycleGO:00002783260.942
Fly
meiotic cell cycleGO:0051321130.941
Yeast Mouse
cell developmentGO:00484683280.934
Fly
regulation of dna metabolic processGO:00510521530.928
regulation of response to dna damage stimulusGO:2001020940.924
dna geometric changeGO:0032392320.924
Yeast
meiotic chromosome segregationGO:004513240.903
meiotic chromosome separationGO:005130730.897
regulation of dna recombinationGO:0000018230.856
dna synthesis involved in dna repairGO:000073160.854
regulation of double strand break repairGO:2000779220.818
dna strand elongationGO:002261650.805
somatic hypermutation of immunoglobulin genesGO:001644610.792
nuclear divisionGO:00002801280.780
Yeast Mouse
double strand break repair via single strand annealingGO:004500240.768
double strand break repair via nonhomologous end joiningGO:0006303100.767
response to radiationGO:00093141510.762
neuron differentiationGO:00301821380.759
Fly
nucleoside catabolic processGO:00091644080.744
atp catabolic processGO:00062001570.740
covalent chromatin modificationGO:00165692540.717
determination of adult lifespanGO:000834020.712
reproductive processGO:00224141060.709
nucleoside triphosphate metabolic processGO:00091414220.699
purine ribonucleoside triphosphate catabolic processGO:00092073910.698
negative regulation of mitotic cell cycle phase transitionGO:1901991850.696
Fly
oogenesisGO:004847720.690
histone modificationGO:00165702510.674
dna damage checkpointGO:0000077680.669
Fly
ribonucleoside catabolic processGO:00424544060.636
protein ubiquitinationGO:00165673140.628
Yeast
amine metabolic processGO:0009308440.618
positive regulation of helicase activityGO:005109660.609
Worm
dna integrity checkpointGO:0031570710.583
Fly
mitotic dna integrity checkpointGO:0044774300.579
Fly
nervous system developmentGO:00073992930.576
Fly
meiotic cell cycle processGO:190304680.554
Yeast
intracellular mrna localizationGO:000829810.551
purine ribonucleoside triphosphate metabolic processGO:00092054110.547
regulation of dna repairGO:0006282470.532
purine nucleoside monophosphate metabolic processGO:00091261860.514
protein dna complex subunit organizationGO:0071824800.512
nucleotide catabolic processGO:00091664080.500
mitotic cell cycle phase transitionGO:00447721620.499
Fly
chromatin modificationGO:00165682980.487
meiotic nuclear divisionGO:0007126100.468
Yeast Mouse
developmental process involved in reproductionGO:0003006660.457
mitotic g1 s transition checkpointGO:0044819170.437
response to abiotic stimulusGO:00096283360.408
ribonucleoside triphosphate metabolic processGO:00091994120.401
regulation of cell cycleGO:00517263930.400
Fly
negative regulation of dna metabolic processGO:0051053570.375
purine ribonucleotide catabolic processGO:00091544040.369
mitotic nuclear divisionGO:00070671190.352
nucleoside phosphate catabolic processGO:19012924120.352
behaviorGO:00076101120.350
purine nucleotide catabolic processGO:00061954050.341
mitotic g1 dna damage checkpointGO:0031571170.334
chromatin organizationGO:00063253510.328
dna packagingGO:0006323770.324
somatic diversification of immune receptors via somatic mutationGO:000256610.321
single organism reproductive processGO:0044702980.308
telomere organizationGO:0032200330.298
cellular amino acid metabolic processGO:00065201160.290
negative regulation of mitotic cell cycleGO:00459301020.278
Fly
vesicle mediated transportGO:00161923710.266
Worm
oocyte developmentGO:004859910.257
cell cycle checkpointGO:00000751170.248
Fly
organelle fissionGO:00482851490.246
Yeast Mouse
response to uvGO:0009411730.244
interstrand cross link repairGO:003629730.240
cell divisionGO:00513011680.236
response to light stimulusGO:0009416870.235
lagging strand elongationGO:000627330.233
development of primary sexual characteristicsGO:0045137350.231
reproductive structure developmentGO:0048608550.213
maintenance of dna repeat elementsGO:004357040.208
purine ribonucleoside metabolic processGO:00461284370.202
purine nucleoside catabolic processGO:00061523980.200
mitotic recombinationGO:000631280.200
Yeast
growthGO:00400072020.200
chromatin remodelingGO:0006338550.188
dna replication initiationGO:000627060.186
histone h3 k4 methylationGO:0051568270.185
g2 dna damage checkpointGO:0031572260.182
Fly
chromosome condensationGO:0030261150.176
chromatin assembly or disassemblyGO:0006333780.176
atp dependent chromatin remodelingGO:0043044250.175
negative regulation of cell cycle processGO:00109481210.175
Fly
ribonucleotide catabolic processGO:00092614050.172
purine containing compound catabolic processGO:00725234110.172
regulation of dna dependent dna replicationGO:0090329190.169
female gamete generationGO:000729220.168
microtubule based processGO:00070172100.161
Fly
regulation of dna replicationGO:0006275680.161
viral processGO:00160321460.147
negative regulation of cell cycleGO:00457861930.143
Fly
regulation of cell cycle processGO:00105642660.142
Fly
sister chromatid cohesionGO:0007062240.138
generation of neuronsGO:00486991520.136
Fly
cellular component disassemblyGO:0022411920.131
multi organism reproductive processGO:0044703540.124
histone exchangeGO:004348630.123
protein dna complex assemblyGO:0065004640.123
nucleosome organizationGO:0034728660.123
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.121
cellular amine metabolic processGO:0044106410.121
purine nucleoside triphosphate metabolic processGO:00091444120.119
regulation of cellular response to stressGO:00801352440.118
reproductionGO:0000003630.116
Yeast Mouse
negative regulation of cell cycle phase transitionGO:1901988890.113
Fly
ribonucleoside triphosphate catabolic processGO:00092033910.113
regulation of dna damage checkpointGO:200000190.110
histone methylationGO:0016571600.109
regulation of dna methylationGO:004403020.107
viral life cycleGO:00190581320.103
microtubule cytoskeleton organizationGO:00002261760.102
Fly
protein alkylationGO:0008213740.101
dna catabolic processGO:0006308490.101
post embryonic developmentGO:000979120.100
rna dependent dna replicationGO:0006278160.095
Yeast
interspecies interaction between organismsGO:00444191560.093
negative regulation of meiotic cell cycleGO:005144720.092
dna biosynthetic processGO:0071897400.092
chromosome segregationGO:00070591140.091
cell cycle phase transitionGO:00447701730.088
Fly
male meiosisGO:000714010.088
cell morphogenesisGO:00009022960.086
Fly
regenerationGO:003109940.080
mitotic dna damage checkpointGO:0044773280.077
Fly
intrinsic apoptotic signaling pathwayGO:00971931270.076
regulation of cell cycle g1 s phase transitionGO:1902806420.073
rna transportGO:0050658390.072
cellular component morphogenesisGO:00329893140.070
Fly
neuron projection developmentGO:00311751060.069
Fly
gonad developmentGO:0008406340.068
hematopoietic stem cell differentiationGO:006021840.066
rna polymerase ii transcriptional preinitiation complex assemblyGO:005112340.061
dna double strand break processingGO:0000729100.058
organophosphate catabolic processGO:00464344300.057
telomere maintenance via recombinationGO:000072240.056
Yeast
cellular ketone metabolic processGO:0042180800.056
blastocyst developmentGO:000182430.055
g1 s transition of mitotic cell cycleGO:0000082780.055
g1 dna damage checkpointGO:0044783180.054
positive regulation of cellular amine metabolic processGO:003324070.054
sex determinationGO:000753030.053
translesion synthesisGO:001998580.053
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediatorGO:0042771230.052
neuron projection morphogenesisGO:0048812500.050
Fly
nuclear exportGO:0051168690.049
cytoplasmic transportGO:00164823790.049
cell projection organizationGO:00300302520.048
Fly
resolution of meiotic recombination intermediatesGO:000071230.048
multicellular organismal reproductive processGO:0048609400.048
regulation of gene expression epigeneticGO:0040029730.047
nuclear transportGO:00511691790.045
cell projection morphogenesisGO:00488581290.045
Fly
negative regulation of g1 s transition of mitotic cell cycleGO:2000134290.045
ribosome assemblyGO:004225590.045
nucleosome assemblyGO:0006334500.045
multicellular organismal agingGO:001025930.045
positive regulation of cellular amino acid metabolic processGO:004576430.043
regulation of mitotic cell cycle phase transitionGO:19019901180.043
Fly
regulation of g1 s transition of mitotic cell cycleGO:2000045400.043
segmentationGO:003528240.043
regulation of growth rateGO:004000910.042
cardiovascular system developmentGO:00723582620.041
Zebrafish
response to inorganic substanceGO:00100351270.041
cellular response to ionizing radiationGO:0071479320.040
heat acclimationGO:001028630.040
cell fate commitmentGO:0045165270.040
developmental maturationGO:0021700280.039
somatic diversification of immunoglobulinsGO:001644560.038
cellular homeostasisGO:00197251960.038
regulation of bindingGO:00510981110.038
cell morphogenesis involved in differentiationGO:00009041440.037
histone lysine methylationGO:0034968500.037
anatomical structure homeostasisGO:00602491000.036
cellular macromolecule catabolic processGO:00442653800.036
sister chromatid segregationGO:0000819540.034
regulation of cellular ketone metabolic processGO:0010565500.034
dendrite morphogenesisGO:0048813140.034
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332370.033
nitrogen compound transportGO:00717051910.033
regulation of cellular amino acid metabolic processGO:000652160.033
anterior posterior axis specificationGO:000994820.033
cellular response to abiotic stimulusGO:00712141170.033
cellular response to oxygen containing compoundGO:19017012760.032
multicellular organism reproductionGO:0032504420.032
regulation of cellular amine metabolic processGO:0033238110.032
gene conversionGO:003582210.032
macromolecule methylationGO:0043414970.032
regulation of cell cycle phase transitionGO:19019871260.031
Fly
receptor mediated endocytosisGO:0006898840.031
Worm
positive regulation of transportGO:00510503360.030
regulation of cell cycle checkpointGO:1901976210.030
rna splicingGO:00083801310.030
cellular response to purine containing compoundGO:007141530.030
regulation of peptidyl lysine acetylationGO:2000756220.030
fertilizationGO:0009566120.030
immune system developmentGO:00025201950.029
Mouse
response to heatGO:0009408210.028
lipid metabolic processGO:00066293810.028
regulation of helicase activityGO:005109580.028
Worm
membrane organizationGO:00610242920.028
dna catabolic process endonucleolyticGO:0000737370.028
agingGO:0007568660.028
negative regulation of cell cycle g1 s phase transitionGO:1902807290.027
epithelium developmentGO:00604292270.027
cellular response to endogenous stimulusGO:00714953360.027
methylationGO:00322591060.027
negative regulation of cell differentiationGO:00455961710.027
somatic diversification of immunoglobulins involved in immune responseGO:000220830.026
adaptive immune responseGO:0002250490.026
positive regulation of developmental processGO:00510943140.026
symbiosis encompassing mutualism through parasitismGO:00444031560.025
endomembrane system organizationGO:00102561960.025
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.025
transcription initiation from rna polymerase ii promoterGO:0006367270.025
neuron developmentGO:00486661130.025
Fly
regulation of intracellular transportGO:00323861950.025
rna localizationGO:0006403410.024
detection of stimulusGO:0051606850.024
negative regulation of cell deathGO:00605483450.024
sex differentiationGO:0007548450.024
response to organic cyclic compoundGO:00140702040.024
embryo developmentGO:00097901230.024
Mouse Worm
negative regulation of dna recombinationGO:004591060.024
negative regulation of developmental processGO:00510932470.023
engulfment of apoptotic cellGO:004365220.023
protein methylationGO:0006479740.023
protein acylationGO:00435431380.023
regulation of multi organism processGO:00439001570.023
central nervous system developmentGO:00074171230.023
negative regulation of apoptotic processGO:00430663160.022
meiotic gene conversionGO:000631110.022
mitotic cell cycle processGO:19030472860.022
Fly
rna interferenceGO:001624640.021
multi organism behaviorGO:0051705140.021
sexual reproductionGO:0019953370.021
cellular response to organic cyclic compoundGO:00714071270.020
nucleic acid phosphodiester bond hydrolysisGO:00903051020.020
actin filament based movementGO:0030048170.020
regulation of histone modificationGO:0031056470.019
neurogenesisGO:00220081690.019
Fly
regulation of developmental growthGO:0048638300.019
defense response to bacteriumGO:0042742630.019
dna damage induced protein phosphorylationGO:000697550.019
endocytosisGO:00068971590.019
Worm
reproductive system developmentGO:0061458560.018
apoptotic signaling pathwayGO:00971902680.018
replication fork processingGO:0031297130.018
regulation of growthGO:00400081650.018
mitotic centrosome separationGO:000710010.017
positive regulation of cellular component organizationGO:00511303760.017
regulation of histone acetylationGO:0035065190.017
ribosomal small subunit export from nucleusGO:000005630.017
viral genome replicationGO:0019079500.017
apoptotic cell clearanceGO:0043277120.017
cellular modified amino acid metabolic processGO:0006575640.017
regulation of meiotic cell cycleGO:005144540.017
regulation of meiosisGO:004002030.017
response to ionizing radiationGO:0010212650.016
regulation of cell divisionGO:00513021160.016
cellular response to radiationGO:0071478650.016
signal transduction in response to dna damageGO:0042770570.016
response to bacteriumGO:00096171440.016
establishment of rna localizationGO:0051236390.016
cell part morphogenesisGO:00329901370.016
Fly
response to external biotic stimulusGO:00432072610.015
nuclear dna replicationGO:003326060.015
regulation of small gtpase mediated signal transductionGO:00510561560.015
regulation of chromosome organizationGO:00330441030.015
regulation of sequence specific dna binding transcription factor activityGO:00510902110.015
spermatogenesisGO:0007283220.015
somatic recombination of immunoglobulin genes involved in immune responseGO:000220430.015
cellular macromolecular complex assemblyGO:00346223240.015
nuclear migrationGO:000709710.015
macromolecule glycosylationGO:0043413630.015
nucleosome positioningGO:001658430.014
defense responseGO:00069523150.014
head developmentGO:00603221080.014
production of molecular mediator of immune responseGO:0002440370.014
chemical homeostasisGO:00488783060.014
negative regulation of programmed cell deathGO:00430693210.014
regulation of viral processGO:00507921030.014
telomere maintenanceGO:0000723320.014
positive regulation of intracellular transportGO:00323881040.014
cellular process involved in reproduction in multicellular organismGO:0022412150.014
spermatid developmentGO:000728640.013
nucleus localizationGO:005164710.013
dna ligationGO:0006266100.013
somatic recombination of immunoglobulin gene segmentsGO:001644740.013
negative regulation of meiosisGO:004583510.013
organelle localizationGO:0051640840.013
germ cell developmentGO:000728180.013
regulation of transcription by chromatin organizationGO:003440110.013
mitotic cell cycle checkpointGO:0007093680.013
Fly
dna dependent dna replication maintenance of fidelityGO:0045005140.012
secretionGO:00469032540.012
multi organism cellular processGO:00447641560.012
cytokinesisGO:0000910960.012
positive regulation of dna metabolic processGO:0051054730.012
immunoglobulin production involved in immunoglobulin mediated immune responseGO:000238150.012
cation transmembrane transportGO:00986552380.012
dna modificationGO:0006304270.012
response to gamma radiationGO:0010332140.012
somatic diversification of immune receptorsGO:000220080.012
nucleus organizationGO:0006997280.012
mrna metabolic processGO:00160711750.011
regulation of mrna processingGO:0050684480.011
response to oxygen containing compoundGO:19017003690.011
negative regulation of catalytic activityGO:00430863350.011
embryo development ending in birth or egg hatchingGO:0009792340.011
Mouse Worm
single organism cellular localizationGO:19025803320.010
regulation of nucleocytoplasmic transportGO:0046822980.010

RPA1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:1621670.154
disease of cellular proliferationDOID:145661740.154
sensory system diseaseDOID:00501552030.108
nervous system diseaseDOID:8634310.108
immune system diseaseDOID:29141550.093
breast cancerDOID:1612210.043
organ system cancerDOID:00506861640.043
thoracic cancerDOID:5093210.043
hematopoietic system diseaseDOID:741000.032
bone marrow diseaseDOID:4961310.032
anemiaDOID:2355550.032
aplastic anemiaDOID:12449300.032
eye and adnexa diseaseDOID:14921500.010