Homo sapiens

54 known processes

TPX2

TPX2, microtubule-associated, homolog (Xenopus laevis)

(Aliases: REPP86,HCA519,HCTP4,p100,FLS353,GD:C20orf1,C20orf2,C20orf1,DIL-2,DIL2)

TPX2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
mitotic nuclear divisionGO:00070671190.887
nuclear divisionGO:00002801280.850
sister chromatid segregationGO:0000819540.848
organelle fissionGO:00482851490.740
spindle midzone assemblyGO:005125540.736
mitotic spindle midzone assemblyGO:005125640.695
spindle assembly involved in mitosisGO:0090307120.694
microtubule cytoskeleton organizationGO:00002261760.681
spindle assemblyGO:0051225290.662
cytokinesisGO:0000910960.632
mitotic sister chromatid segregationGO:0000070530.629
microtubule based processGO:00070172100.600
regulation of cell cycleGO:00517263930.595
mitotic cell cycleGO:00002783260.568
mitotic cell cycle processGO:19030472860.549
chromosome segregationGO:00070591140.539
meiotic chromosome segregationGO:004513240.534
cytoskeleton dependent cytokinesisGO:0061640220.526
spindle elongationGO:005123140.473
microtubule polymerization or depolymerizationGO:0031109370.404
single organism cellular localizationGO:19025803320.401
mitotic spindle elongationGO:000002240.336
cellular protein complex disassemblyGO:0043624360.321
establishment of organelle localizationGO:0051656590.302
spindle organizationGO:0007051530.288
establishment of nucleus localizationGO:004002310.287
cellular macromolecular complex assemblyGO:00346223240.282
ubiquitin dependent protein catabolic processGO:00065112060.242
purine nucleoside monophosphate catabolic processGO:00091281580.236
atp catabolic processGO:00062001570.221
ribonucleoside triphosphate catabolic processGO:00092033910.221
dna conformation changeGO:00711031130.212
nucleus localizationGO:005164710.202
negative regulation of mitotic metaphase anaphase transitionGO:0045841170.195
mitotic spindle organizationGO:0007052270.194
cellular macromolecule catabolic processGO:00442653800.192
organelle localizationGO:0051640840.185
establishment or maintenance of cytoskeleton polarityGO:003095230.183
establishment of spindle localizationGO:0051293120.182
regulation of microtubule based processGO:0032886740.179
cell divisionGO:00513011680.171
regulation of spindle organizationGO:0090224100.163
spindle stabilizationGO:004314640.162
cellular protein complex assemblyGO:00436231880.162
nucleoside triphosphate catabolic processGO:00091433940.158
mitotic cytokinesisGO:0000281190.158
microtubule anchoringGO:0034453240.154
positive regulation of cell cycleGO:00457871400.153
regulation of mitotic cell cycleGO:00073461890.150
nuclear migrationGO:000709710.147
regulation of cell cycle processGO:00105642660.139
negative regulation of cellular component organizationGO:00511292350.133
nucleoside triphosphate metabolic processGO:00091414220.131
microtubule nucleationGO:000702060.129
regulation of chromosome segregationGO:0051983440.125
ribonucleoside monophosphate metabolic processGO:00091611870.123
purine ribonucleotide catabolic processGO:00091544040.122
regulation of cytoplasmic transportGO:19036491490.115
mitotic cell cycle phase transitionGO:00447721620.112
ribonucleoside catabolic processGO:00424544060.112
centrosome organizationGO:0051297580.109
regulation of protein localizationGO:00328802960.106
ribonucleotide catabolic processGO:00092614050.104
purine ribonucleoside monophosphate metabolic processGO:00091671860.104
oocyte differentiationGO:000999420.104
meiotic nuclear divisionGO:0007126100.103
regulation of mitotic sister chromatid segregationGO:0033047270.099
ribonucleoside triphosphate metabolic processGO:00091994120.099
chromatin organizationGO:00063253510.097
maintenance of location in cellGO:0051651620.096
negative regulation of microtubule polymerization or depolymerizationGO:0031111170.096
organelle assemblyGO:00709251760.095
negative regulation of cell cycleGO:00457861930.091
dna packagingGO:0006323770.091
macromolecular complex disassemblyGO:0032984600.088
single fertilizationGO:0007338110.086
meiosis iGO:000712740.083
female gamete generationGO:000729220.082
regulation of microtubule polymerization or depolymerizationGO:0031110270.079
purine nucleoside triphosphate catabolic processGO:00091463920.077
regulation of microtubule cytoskeleton organizationGO:0070507610.076
nucleoside monophosphate catabolic processGO:00091251590.075
protein depolymerizationGO:0051261300.075
nucleoside catabolic processGO:00091644080.075
nucleoside monophosphate metabolic processGO:00091231910.075
maintenance of locationGO:00512351120.074
purine ribonucleoside triphosphate metabolic processGO:00092054110.073
modification dependent macromolecule catabolic processGO:00436322120.073
nervous system developmentGO:00073992930.072
purine nucleoside monophosphate metabolic processGO:00091261860.071
chromatin modificationGO:00165682980.068
protein processingGO:00164852260.066
nucleotide catabolic processGO:00091664080.066
positive regulation of developmental processGO:00510943140.065
microtubule cytoskeleton organization involved in mitosisGO:1902850150.064
intracellular protein transportGO:00068862700.063
organophosphate catabolic processGO:00464344300.062
purine ribonucleoside catabolic processGO:00461303980.062
nucleocytoplasmic transportGO:00069131760.061
cell cycle phase transitionGO:00447701730.060
protein complex disassemblyGO:0043241520.060
cell developmentGO:00484683280.060
regulation of cytokinesisGO:0032465450.060
cellular response to dna damage stimulusGO:00069743790.059
protein maturationGO:00516042330.058
post embryonic developmentGO:000979120.056
purine nucleoside catabolic processGO:00061523980.056
regulation of cellular component biogenesisGO:00440872810.056
positive regulation of cell cycle processGO:00900681060.055
positive regulation of cellular component organizationGO:00511303760.055
nucleoside phosphate catabolic processGO:19012924120.054
cellular amino acid metabolic processGO:00065201160.053
oogenesisGO:004847720.052
regulation of cell differentiationGO:00455953930.052
regulation of cytoskeleton organizationGO:00514931770.052
cell morphogenesisGO:00009022960.051
purine ribonucleoside metabolic processGO:00461284370.051
regulation of intracellular protein transportGO:00331571230.051
positive regulation of proteolysisGO:00458621420.049
regulation of cell divisionGO:00513021160.049
regenerationGO:003109940.049
negative regulation of protein metabolic processGO:00512483910.048
regulation of establishment of protein localizationGO:00702012420.047
mitotic centrosome separationGO:000710010.047
protein dephosphorylationGO:0006470810.047
purine containing compound catabolic processGO:00725234110.046
regulation of nucleocytoplasmic transportGO:0046822980.045
regulation of cell cycle phase transitionGO:19019871260.045
regulation of protein localization to nucleusGO:1900180850.044
glycosyl compound catabolic processGO:19016584130.044
cellular component disassemblyGO:0022411920.044
maintenance of protein locationGO:0045185570.044
ras protein signal transductionGO:0007265730.042
protein import into nucleusGO:00066061040.042
positive regulation of cytokinesisGO:0032467290.042
purine nucleoside triphosphate metabolic processGO:00091444120.042
microtubule organizing center organizationGO:0031023620.042
positive regulation of protein transportGO:00512221350.041
positive regulation of transferase activityGO:00513472270.041
negative regulation of proteolysisGO:00458611320.040
vesicle mediated transportGO:00161923710.039
microtubule depolymerizationGO:0007019180.039
centrosome duplicationGO:0051298280.038
histone modificationGO:00165702510.038
proteasomal protein catabolic processGO:00104981760.037
microtubule based movementGO:0007018320.037
establishment of cell polarityGO:0030010220.037
protein catabolic processGO:00301633250.037
protein targeting to nucleusGO:00447441040.036
establishment or maintenance of microtubule cytoskeleton polarityGO:003095120.036
negative regulation of cellular protein metabolic processGO:00322693530.035
regulation of intracellular transportGO:00323861950.035
protein localization to nucleusGO:00345041360.035
establishment of spindle orientationGO:005129490.034
purine ribonucleoside monophosphate catabolic processGO:00091691580.034
centrosome separationGO:005129930.033
protein targetingGO:00066051870.033
metaphase anaphase transition of mitotic cell cycleGO:0007091210.033
dephosphorylationGO:00163112090.033
single organism reproductive processGO:0044702980.033
anatomical structure formation involved in morphogenesisGO:00486462840.033
small gtpase mediated signal transductionGO:0007264780.033
establishment or maintenance of cell polarityGO:0007163310.032
negative regulation of mitotic cell cycleGO:00459301020.032
negative regulation of protein complex disassemblyGO:0043242200.032
embryo developmentGO:00097901230.032
protein polymerizationGO:0051258710.032
cell projection organizationGO:00300302520.032
proteolysis involved in cellular protein catabolic processGO:00516032440.031
modification dependent protein catabolic processGO:00199412090.031
regulation of protein polymerizationGO:0032271630.031
response to hormoneGO:00097251750.031
chromosome condensationGO:0030261150.031
positive regulation of catabolic processGO:00098963100.030
nuclear importGO:00511701060.030
negative regulation of cell cycle processGO:00109481210.029
regulation of transferase activityGO:00513383550.029
negative regulation of peptidase activityGO:0010466910.029
mitotic sister chromatid separationGO:0051306180.029
reproductionGO:0000003630.029
regulation of transcription factor import into nucleusGO:0042990390.028
attachment of spindle microtubules to kinetochoreGO:0008608170.028
ribonucleoside monophosphate catabolic processGO:00091581580.028
meiotic cell cycleGO:0051321130.028
purine ribonucleoside triphosphate catabolic processGO:00092073910.027
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.027
cellular component morphogenesisGO:00329893140.027
regulation of nuclear divisionGO:0051783650.027
cytoplasmic transportGO:00164823790.027
positive regulation of mitosisGO:0045840250.027
protein localization to organelleGO:00333652800.027
establishment of protein localization to organelleGO:00725941720.027
response to organic cyclic compoundGO:00140702040.027
regulation of proteolysisGO:00301622930.026
regulation of mitotic spindle organizationGO:006023660.026
protein ubiquitinationGO:00165673140.026
negative regulation of protein processingGO:00109551420.026
mrna processingGO:00063971330.026
neurogenesisGO:00220081690.025
positive regulation of cellular catabolic processGO:00313312840.025
sister chromatid biorientationGO:003113420.024
cellular homeostasisGO:00197251960.024
reproductive processGO:00224141060.024
cellular ketone metabolic processGO:0042180800.024
regulation of protein complex assemblyGO:00432541470.024
positive regulation of attachment of spindle microtubules to kinetochoreGO:005198720.024
response to oxygen containing compoundGO:19017003690.024
metaphase plate congressionGO:0051310180.023
negative regulation of hydrolase activityGO:00513461820.023
covalent chromatin modificationGO:00165692540.023
regulation of kinase activityGO:00435493140.023
regulation of bindingGO:00510981110.023
reciprocal dna recombinationGO:003582540.023
regulation of protein import into nucleusGO:0042306780.022
regulation of protein processingGO:00706131500.022
purine nucleotide catabolic processGO:00061954050.021
intracellular mrna localizationGO:000829810.021
regulation of attachment of spindle microtubules to kinetochoreGO:005198890.021
negative regulation of phosphorus metabolic processGO:00105632670.021
dna recombinationGO:0006310770.021
histone serine phosphorylationGO:003540440.020
dna repairGO:00062811980.020
carbohydrate derivative biosynthetic processGO:19011372070.020
neuroblast proliferationGO:000740540.020
anterior posterior axis specificationGO:000994820.020
lung cell differentiationGO:006047910.020
neuron differentiationGO:00301821380.019
negative regulation of organelle organizationGO:00106391260.019
regulation of purine nucleotide catabolic processGO:00331212050.019
positive regulation of cell divisionGO:0051781590.019
circulatory system developmentGO:00723592620.019
positive regulation of exit from mitosisGO:003153620.019
oocyte developmentGO:004859910.019
growthGO:00400072020.019
cell cycle checkpointGO:00000751170.019
cardiovascular system developmentGO:00723582620.018
protein importGO:00170381300.018
coenzyme metabolic processGO:0006732650.018
negative regulation of cell deathGO:00605483450.018
regulation of peptidase activityGO:00525471800.018
blood vessel morphogenesisGO:00485141620.018
cellular amine metabolic processGO:0044106410.018
endocytosisGO:00068971590.018
oocyte maturationGO:000155610.018
cell morphogenesis involved in differentiationGO:00009041440.018
regulation of mitotic metaphase anaphase transitionGO:0030071260.018
response to organophosphorusGO:0046683410.018
protein modification by small protein conjugationGO:00324463420.017
developmental growthGO:0048589480.017
cell part morphogenesisGO:00329901370.017
regulation of mitotic cell cycle phase transitionGO:19019901180.017
fertilizationGO:0009566120.017
regulation of cellular protein catabolic processGO:1903362960.017
regulation of cellular amine metabolic processGO:0033238110.017
regulation of cell developmentGO:00602841610.017
blastocyst developmentGO:000182430.017
regulation of multi organism processGO:00439001570.017
negative regulation of programmed cell deathGO:00430693210.017
chromosome separationGO:0051304230.017
determination of adult lifespanGO:000834020.017
positive regulation of intracellular transportGO:00323881040.017
signal transduction by phosphorylationGO:00230142970.017
response to nitrogen compoundGO:19016981840.017
hematopoietic or lymphoid organ developmentGO:00485341860.017
single organism nuclear importGO:19025931040.017
regulation of protein transportGO:00512232130.016
epithelium developmentGO:00604292270.016
negative regulation of protein maturationGO:19033181420.016
generation of neuronsGO:00486991520.016
cellular response to endogenous stimulusGO:00714953360.016
positive regulation of transportGO:00510503360.016
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.016
regulation of protein catabolic processGO:00421761550.016
nucleotide biosynthetic processGO:00091651090.016
negative regulation of endopeptidase activityGO:0010951840.016
negative regulation of apoptotic processGO:00430663160.016
positive regulation of cell proliferationGO:00082843010.016
microtubule polymerizationGO:0046785180.016
regulation of protein maturationGO:19033171500.015
somatic stem cell divisionGO:004810310.015
immune system developmentGO:00025201950.015
peptidyl threonine modificationGO:0018210450.015
negative regulation of transportGO:00510511760.015
neuron developmentGO:00486661130.015
positive regulation of mitotic sister chromatid separationGO:190197060.015
spindle checkpointGO:0031577260.015
single organism membrane organizationGO:00448022680.015
regulation of nervous system developmentGO:0051960880.015
negative regulation of cell differentiationGO:00455961710.015
ribosome assemblyGO:004225590.014
negative regulation of mitotic cell cycle phase transitionGO:1901991850.014
peptidyl serine phosphorylationGO:00181051010.014
response to drugGO:0042493810.014
positive regulation of chromosome organizationGO:2001252410.014
regulation of mitotic sister chromatid separationGO:0010965270.014
establishment of chromosome localizationGO:0051303200.014
regulation of protein targetingGO:1903533910.014
response to hypoxiaGO:0001666960.014
cytokinesis completion of separationGO:000710930.014
posttranscriptional regulation of gene expressionGO:00106082130.014
regulation of small gtpase mediated signal transductionGO:00510561560.014
mapk cascadeGO:00001652880.014
regulation of cellular ketone metabolic processGO:0010565500.014
regulation of response to dna damage stimulusGO:2001020940.013
histone phosphorylationGO:0016572160.013
positive regulation of organelle organizationGO:00106381950.013
regulation of chromosome organizationGO:00330441030.013
reciprocal meiotic recombinationGO:000713140.013
regulation of protein stabilityGO:0031647870.013
positive regulation of phosphorylationGO:00423273940.013
maintenance of protein location in cellGO:0032507560.013
negative regulation of cell cycle phase transitionGO:1901988890.013
regulation of proteasomal protein catabolic processGO:0061136870.012
positive regulation of cellular amino acid metabolic processGO:004576430.012
cell projection morphogenesisGO:00488581290.012
regulation of cellular amino acid metabolic processGO:000652160.012
regulation of cellular response to stressGO:00801352440.012
response to purine containing compoundGO:0014074400.012
peptidyl serine modificationGO:00182091060.012
male meiosisGO:000714010.012
reproductive structure developmentGO:0048608550.012
regulation of protein bindingGO:0043393660.012
multi organism reproductive processGO:0044703540.012
negative regulation of cytoskeleton organizationGO:0051494450.012
actin filament based processGO:00300292240.012
secretionGO:00469032540.012
mitotic chromosome condensationGO:0007076110.011
negative regulation of phosphate metabolic processGO:00459362670.011
positive regulation of intracellular protein transportGO:0090316760.011
cellular response to oxygen containing compoundGO:19017012760.011
positive regulation of programmed cell deathGO:00430682490.011
regulation of endopeptidase activityGO:00525481700.011
cytokinetic processGO:0032506120.011
atp metabolic processGO:00460341760.011
response to radiationGO:00093141510.011
protein polyubiquitinationGO:00002091100.011
negative regulation of phosphorylationGO:00423261740.011
regulation of mitosisGO:0007088630.011
microtubule bundle formationGO:0001578150.011
positive regulation of protein polymerizationGO:0032273450.011
protein localization to chromosome centromeric regionGO:0071459120.011
stress activated protein kinase signaling cascadeGO:0031098940.011
actin cytoskeleton organizationGO:00300362070.011
cellular lipid metabolic processGO:00442553030.011
regulation of purine nucleotide metabolic processGO:19005422640.010
positive regulation of protein kinase activityGO:00458601900.010
tube morphogenesisGO:0035239950.010
anatomical structure homeostasisGO:00602491000.010
neuroblast divisionGO:005505710.010
positive regulation of kinase activityGO:00336742040.010
defense responseGO:00069523150.010
response to oxygen levelsGO:00704821000.010
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.010
regulation of cell adhesionGO:00301551660.010
chemical homeostasisGO:00488783060.010
positive regulation of nuclear divisionGO:0051785270.010
reactive oxygen species metabolic processGO:0072593750.010
endomembrane system organizationGO:00102561960.010
response to light stimulusGO:0009416870.010

TPX2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.258
cancerDOID:1621670.173
organ system cancerDOID:00506861640.041
breast cancerDOID:1612210.014
thoracic cancerDOID:5093210.014
gastrointestinal system cancerDOID:3119520.013