Homo sapiens

123 known processes

DENND2D

DENN/MADD domain containing 2D

(Aliases: FLJ22457,RP5-1180E21.2)

DENND2D biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular ketone metabolic processGO:0042180800.064
post embryonic developmentGO:000979120.064
cellular amino acid metabolic processGO:00065201160.058
ribonucleoside catabolic processGO:00424544060.057
nucleoside catabolic processGO:00091644080.056
regulation of cellular amine metabolic processGO:0033238110.055
organophosphate catabolic processGO:00464344300.055
purine nucleoside triphosphate catabolic processGO:00091463920.053
regulation of cellular amino acid metabolic processGO:000652160.053
cellular amine metabolic processGO:0044106410.052
purine containing compound catabolic processGO:00725234110.052
ras protein signal transductionGO:0007265730.051
purine ribonucleotide catabolic processGO:00091544040.051
amine metabolic processGO:0009308440.050
purine ribonucleoside triphosphate catabolic processGO:00092073910.049
purine ribonucleoside metabolic processGO:00461284370.049
ribonucleoside triphosphate catabolic processGO:00092033910.048
immune responseGO:00069553070.048
ribonucleotide catabolic processGO:00092614050.048
purine nucleoside triphosphate metabolic processGO:00091444120.046
multicellular organismal agingGO:001025930.046
purine ribonucleoside triphosphate metabolic processGO:00092054110.046
nucleoside triphosphate metabolic processGO:00091414220.045
nucleoside phosphate catabolic processGO:19012924120.044
nucleoside triphosphate catabolic processGO:00091433940.044
cytokine productionGO:00018162470.044
regulation of transferase activityGO:00513383550.043
nucleotide catabolic processGO:00091664080.043
purine ribonucleoside catabolic processGO:00461303980.043
mapk cascadeGO:00001652880.042
Human
positive regulation of phosphorylationGO:00423273940.042
Human
glycosyl compound catabolic processGO:19016584130.041
positive regulation of transportGO:00510503360.041
signal transduction by phosphorylationGO:00230142970.039
Human
positive regulation of apoptotic processGO:00430652460.039
positive regulation of cell deathGO:00109422630.039
positive regulation of hydrolase activityGO:00513453310.038
single organism cellular localizationGO:19025803320.038
guanosine containing compound catabolic processGO:19010692390.038
positive regulation of cytokine productionGO:00018191670.038
rho protein signal transductionGO:0007266260.038
purine nucleoside catabolic processGO:00061523980.037
positive regulation of cellular amine metabolic processGO:003324070.037
regulation of protein localizationGO:00328802960.036
positive regulation of cellular amino acid metabolic processGO:004576430.036
gtp metabolic processGO:00460392390.035
membrane organizationGO:00610242920.035
small gtpase mediated signal transductionGO:0007264780.035
defense responseGO:00069523150.035
cytoplasmic transportGO:00164823790.035
positive regulation of immune system processGO:00026842830.035
regulation of sequence specific dna binding transcription factor activityGO:00510902110.035
anatomical structure formation involved in morphogenesisGO:00486462840.035
gtp catabolic processGO:00061842370.035
response to lipidGO:00339932060.034
negative regulation of catalytic activityGO:00430863350.034
regulation of locomotionGO:00400123290.034
regulation of secretionGO:00510461940.034
positive regulation of cellular component organizationGO:00511303760.034
endomembrane system organizationGO:00102561960.033
cellular macromolecule catabolic processGO:00442653800.033
cell activationGO:00017752130.033
regulation of cytokine productionGO:00018172320.033
regulation of establishment of protein localizationGO:00702012420.033
single organism membrane organizationGO:00448022680.033
determination of adult lifespanGO:000834020.032
secretion by cellGO:00329402260.032
guanosine containing compound metabolic processGO:19010682440.032
cellular macromolecular complex assemblyGO:00346223240.032
purine nucleotide catabolic processGO:00061954050.031
positive regulation of programmed cell deathGO:00430682490.031
regulation of anatomical structure morphogenesisGO:00226032860.031
regulation of mapk cascadeGO:00434082620.031
Human
activation of immune responseGO:00022531140.030
positive regulation of immune responseGO:00507781590.030
female gamete generationGO:000729220.030
regulation of immune responseGO:00507762010.030
ribonucleoside triphosphate metabolic processGO:00091994120.030
oogenesisGO:004847720.030
regulation of secretion by cellGO:19035301770.030
cellular protein catabolic processGO:00442572610.029
regulation of proteolysisGO:00301622930.029
regulation of cell motilityGO:20001452990.029
negative regulation of phosphorus metabolic processGO:00105632670.029
regulation of cell differentiationGO:00455953930.029
negative regulation of protein metabolic processGO:00512483910.029
transmembrane transportGO:00550853990.029
negative regulation of phosphate metabolic processGO:00459362670.029
response to oxygen containing compoundGO:19017003690.029
cellular response to endogenous stimulusGO:00714953360.028
secretionGO:00469032540.028
regulation of lymphocyte activationGO:00512491030.028
immune effector processGO:00022521590.028
cellular lipid metabolic processGO:00442553030.028
positive regulation of catabolic processGO:00098963100.028
regulation of kinase activityGO:00435493140.028
positive regulation of mapk cascadeGO:00434101900.028
Human
positive regulation of purine nucleotide metabolic processGO:19005442270.028
regulation of cellular component movementGO:00512703340.028
regenerationGO:003109940.028
lipid metabolic processGO:00066293810.028
response to abiotic stimulusGO:00096283360.027
positive regulation of cell proliferationGO:00082843010.027
regulation of protein transportGO:00512232130.027
regulation of i kappab kinase nf kappab signalingGO:00431221620.027
cell adhesionGO:00071553250.027
negative regulation of cellular protein metabolic processGO:00322693530.027
system processGO:00030083490.027
biological adhesionGO:00226103310.026
cellular response to dna damage stimulusGO:00069743790.026
regulation of cellular ketone metabolic processGO:0010565500.026
positive regulation of cellular catabolic processGO:00313312840.026
vesicle mediated transportGO:00161923710.026
Human
intracellular protein transportGO:00068862700.026
proteolysis involved in cellular protein catabolic processGO:00516032440.025
actin filament based processGO:00300292240.025
oxidation reduction processGO:00551143960.025
protein catabolic processGO:00301633250.025
protein localization to organelleGO:00333652800.025
t cell activationGO:0042110990.025
regulation of intracellular transportGO:00323861950.025
cation transportGO:00068123310.024
negative regulation of transportGO:00510511760.024
lymphocyte activationGO:00466491330.024
regulation of cellular response to stressGO:00801352440.024
cellular response to oxygen containing compoundGO:19017012760.024
regulation of defense responseGO:00313471540.024
response to other organismGO:00517072610.024
response to external biotic stimulusGO:00432072610.024
negative regulation of multicellular organismal processGO:00512413170.024
segmentationGO:003528240.024
locomotory behaviorGO:000762610.023
protein targetingGO:00066051870.023
response to biotic stimulusGO:00096072760.023
regulation of cell cycle processGO:00105642660.023
regulation of nucleotide metabolic processGO:00061402690.023
neuromuscular junction developmentGO:000752830.023
protein maturationGO:00516042330.023
positive regulation of purine nucleotide catabolic processGO:00331231850.023
i kappab kinase nf kappab signalingGO:00072491660.023
apoptotic signaling pathwayGO:00971902680.023
t cell differentiation in thymusGO:003307740.023
regulation of nucleoside metabolic processGO:00091182090.022
regulation of protein kinase activityGO:00458592890.022
regulation of leukocyte activationGO:00026941150.022
cellular component morphogenesisGO:00329893140.022
ion transmembrane transportGO:00342203380.022
regulation of small gtpase mediated signal transductionGO:00510561560.022
regulation of cell migrationGO:00303342890.022
regulation of cell cycleGO:00517263930.022
protein localization to membraneGO:00726571600.022
regulation of purine nucleotide metabolic processGO:19005422640.022
detection of muramyl dipeptideGO:003249810.022
regulation of response to external stimulusGO:00321012220.022
carbohydrate metabolic processGO:00059752070.022
dephosphorylationGO:00163112090.022
regulation of nucleotide catabolic processGO:00308112050.022
nitrogen compound transportGO:00717051910.021
regulation of gtpase activityGO:00430871800.021
negative regulation of cell deathGO:00605483450.021
positive regulation of cell differentiationGO:00455972110.021
innate immune responseGO:00450871780.021
angiogenesisGO:00015251470.021
cellular homeostasisGO:00197251960.021
cell morphogenesisGO:00009022960.021
protein oligomerizationGO:00512591730.020
negative regulation of intracellular signal transductionGO:19025321830.020
mitotic cell cycleGO:00002783260.020
release of cytoplasmic sequestered nf kappabGO:000858840.020
circulatory system developmentGO:00723592620.020
immune response regulating signaling pathwayGO:0002764970.020
negative regulation of hydrolase activityGO:00513461820.020
multi organism cellular processGO:00447641560.020
positive regulation of locomotionGO:00400171860.020
enzyme linked receptor protein signaling pathwayGO:00071673030.020
immune response activating signal transductionGO:0002757900.020
regulation of cellular component biogenesisGO:00440872810.020
negative regulation of apoptotic processGO:00430663160.020
metal ion transportGO:00300012720.019
single organism carbohydrate metabolic processGO:00447231930.019
regulation of gtp catabolic processGO:00331241800.019
protein processingGO:00164852260.019
divalent inorganic cation transportGO:00725111580.019
negative regulation of cellular component organizationGO:00511292350.019
leukocyte activationGO:00453211640.019
negative regulation of programmed cell deathGO:00430693210.019
blastoderm segmentationGO:000735020.019
positive regulation of gtpase activityGO:00435471660.019
response to virusGO:00096151260.019
interspecies interaction between organismsGO:00444191560.018
positive regulation of kinase activityGO:00336742040.018
response to cytokineGO:00340972320.018
maintenance of locationGO:00512351120.018
positive regulation of cell activationGO:0050867810.018
protein ubiquitinationGO:00165673140.018
regulation of ras protein signal transductionGO:00465781550.018
positive regulation of protein transportGO:00512221350.018
positive regulation of nf kappab transcription factor activityGO:0051092810.018
regulation of protein secretionGO:0050708860.018
regulation of cell activationGO:00508651250.018
positive regulation of organelle organizationGO:00106381950.018
compound eye developmentGO:004874910.018
symbiosis encompassing mutualism through parasitismGO:00444031560.018
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.017
positive regulation of secretionGO:00510471160.017
regulation of apoptotic signaling pathwayGO:20012331750.017
memoryGO:000761330.017
morphogenesis of embryonic epitheliumGO:001633140.017
anion transportGO:00068201610.017
regulation of peptidase activityGO:00525471800.017
cellular response to nitrogen compoundGO:19016991440.017
ubiquitin dependent protein catabolic processGO:00065112060.017
oocyte developmentGO:004859910.017
reactive oxygen species metabolic processGO:0072593750.017
negative regulation of protein modification processGO:00314002000.017
hemopoiesisGO:00300971800.017
negative regulation of cellular amino acid metabolic processGO:004576320.017
positive regulation of nucleoside metabolic processGO:00459791860.017
neurological system processGO:00508771630.017
positive regulation of lymphocyte activationGO:0051251730.017
chemical homeostasisGO:00488783060.017
establishment of protein localization to organelleGO:00725941720.017
cellular protein complex assemblyGO:00436231880.017
regulation of cytoplasmic transportGO:19036491490.017
positive regulation of nucleotide metabolic processGO:00459812300.017
vasculature developmentGO:00019441810.017
positive regulation of cellular component movementGO:00512721810.016
small molecule biosynthetic processGO:00442831570.016
cardiovascular system developmentGO:00723582620.016
regulation of cytoskeleton organizationGO:00514931770.016
blood vessel morphogenesisGO:00485141620.016
organic hydroxy compound metabolic processGO:19016151470.016
negative regulation of phosphorylationGO:00423261740.016
regulation of innate immune responseGO:0045088970.016
positive regulation of gtp catabolic processGO:00331261660.016
negative regulation of cellular amine metabolic processGO:003323930.016
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.016
positive regulation of protein kinase activityGO:00458601900.016
regulation of endopeptidase activityGO:00525481700.016
posttranscriptional regulation of gene expressionGO:00106082130.016
protein modification by small protein conjugationGO:00324463420.016
positive regulation of leukocyte activationGO:0002696800.016
sensory perception of smellGO:000760820.016
cellular response to organonitrogen compoundGO:00714171240.016
anterior posterior axis specificationGO:000994820.016
negative regulation of cell cycleGO:00457861930.016
cellular response to cytokine stimulusGO:00713451810.016
cell developmentGO:00484683280.016
growthGO:00400072020.016
modification dependent macromolecule catabolic processGO:00436322120.016
nucleocytoplasmic transportGO:00069131760.016
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555440.016
lymphocyte proliferationGO:0046651700.015
viral processGO:00160321460.015
regulation of multi organism processGO:00439001570.015
negative regulation of developmental processGO:00510932470.015
positive regulation of protein phosphorylationGO:00019343130.015
regulation of ras gtpase activityGO:00323181280.015
actin cytoskeleton organizationGO:00300362070.015
mitotic cell cycle processGO:19030472860.015
cation homeostasisGO:00550801890.015
oocyte differentiationGO:000999420.015
plasma membrane organizationGO:00070091150.015
positive regulation of innate immune responseGO:0045089790.015
organophosphate biosynthetic processGO:00904071630.015
regulation of protein maturationGO:19033171500.015
regulation of protein complex assemblyGO:00432541470.015
positive regulation of developmental processGO:00510943140.015
sensory perception of painGO:001923340.015
nuclear transportGO:00511691790.015
spermatid differentiationGO:004851540.015
histone modificationGO:00165702510.015
response to organonitrogen compoundGO:00102431560.015
rhythmic behaviorGO:000762220.015
stress activated mapk cascadeGO:0051403930.015
establishment of protein localization to membraneGO:00901501210.015
cellular cation homeostasisGO:00300031630.015
endosomal transportGO:00161971290.015
Human
positive regulation of ras gtpase activityGO:00323201170.015
regulation of actin filament based processGO:00329701410.015
covalent chromatin modificationGO:00165692540.015
chromatin organizationGO:00063253510.014
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.014
regulation of synaptic plasticityGO:004816730.014
cell fate determinationGO:000170930.014
reactive oxygen species biosynthetic processGO:190340940.014
matingGO:000761810.014
regulation of purine nucleotide catabolic processGO:00331212050.014
peripheral nervous system developmentGO:000742220.014
cell projection organizationGO:00300302520.014
negative regulation of protein phosphorylationGO:00019331400.014
chromatin modificationGO:00165682980.014
lipid biosynthetic processGO:00086101770.014
organonitrogen compound biosynthetic processGO:19015662000.014
negative regulation of immune system processGO:00026831360.014
immune system developmentGO:00025201950.014
cell growthGO:00160491600.014
divalent metal ion transportGO:00708381520.014
ion homeostasisGO:00508012300.014
peptidyl tyrosine modificationGO:00182121700.014
chemotaxisGO:00069351570.014
adult locomotory behaviorGO:000834410.014
regulation of angiogenesisGO:0045765920.014
positive regulation of cell migrationGO:00303351720.014
proteasomal protein catabolic processGO:00104981760.014
cellular response to lipidGO:00713961270.014
protein secretionGO:0009306980.014
negative regulation of protein processingGO:00109551420.014
regulation of intracellular protein transportGO:00331571230.014
modification dependent protein catabolic processGO:00199412090.014
nervous system developmentGO:00073992930.014
positive regulation of proteolysisGO:00458621420.014
positive regulation of nucleotide catabolic processGO:00308131850.014
response to hormoneGO:00097251750.014
regulation of cytokine secretionGO:0050707570.014
positive regulation of cell motilityGO:20001471770.014
cell projection assemblyGO:00300311260.013
g protein coupled receptor signaling pathwayGO:00071862070.013
response to nitrogen compoundGO:19016981840.013
regulation of protein processingGO:00706131500.013
monocarboxylic acid metabolic processGO:00327871850.013
regulation of ion transportGO:00432691890.013
mitochondrion organizationGO:00070051560.013
regulation of protein catabolic processGO:00421761550.013
circadian behaviorGO:004851220.013
response to growth factorGO:00708482050.013
cellular ion homeostasisGO:00068731680.013
epithelium developmentGO:00604292270.013
regulation of vasculature developmentGO:1901342970.013
positive regulation of transferase activityGO:00513472270.013
protein homooligomerizationGO:00512601000.013
protein autophosphorylationGO:00467771230.013
peptidyl tyrosine phosphorylationGO:00181081700.013
blood vessel developmentGO:00015681720.013
spermatid developmentGO:000728640.013
single organism cell adhesionGO:00986021790.013
positive regulation of defense responseGO:0031349870.013
cytokine biosynthetic processGO:0042089370.013
hematopoietic or lymphoid organ developmentGO:00485341860.013
syncytium formation by plasma membrane fusionGO:000076820.013
inner ear morphogenesisGO:004247240.013
carbohydrate derivative biosynthetic processGO:19011372070.013
negative regulation of proteolysisGO:00458611320.013
anatomical structure homeostasisGO:00602491000.013
activation of innate immune responseGO:0002218550.013
regulation of cell adhesionGO:00301551660.013
jnk cascadeGO:0007254800.013
regulation of protein serine threonine kinase activityGO:00719001790.013
negative regulation of cell proliferationGO:00082852280.013
cation transmembrane transportGO:00986552380.013
rna processingGO:00063962550.013
regulation of neural precursor cell proliferationGO:200017740.013
regulation of growthGO:00400081650.013
rna interferenceGO:001624640.013
glycoprotein metabolic processGO:00091001100.013
negative regulation of cellular catabolic processGO:0031330830.012
cellular response to growth factor stimulusGO:00713631970.012
cellular chemical homeostasisGO:00550821800.012
intracellular receptor signaling pathwayGO:00305221040.012
regulation of stress activated protein kinase signaling cascadeGO:0070302850.012
embryonic epithelial tube formationGO:000183840.012
regulation of dna metabolic processGO:00510521530.012
cell cycle phase transitionGO:00447701730.012
protein import into nucleusGO:00066061040.012
cellular response to nutrient levelsGO:0031669690.012
alcohol metabolic processGO:00060661140.012
regulation of cell morphogenesisGO:00226041530.012
response to fungusGO:000962040.012
negative regulation of cytokine productionGO:0001818820.012
defense response to other organismGO:00985421290.012
neurotransmitter secretionGO:000726940.012
organic acid biosynthetic processGO:0016053970.012
negative regulation of catabolic processGO:00098951040.012
protein localization to nucleusGO:00345041360.012
anterior posterior axis specification embryoGO:000859520.012
regulation of vesicle mediated transportGO:00606271300.012
response to woundingGO:00096111680.012
regulation of bindingGO:00510981110.012
negative regulation of protein transportGO:0051224750.012
thymus developmentGO:004853830.012
protein acylationGO:00435431380.012
response to salt stressGO:000965130.012
post embryonic organ developmentGO:004856910.012
hindbrain developmentGO:003090230.012
regulation of cell developmentGO:00602841610.012
stress activated protein kinase signaling cascadeGO:0031098940.012
regulation of transmembrane transportGO:00347621390.012
positive regulation of secretion by cellGO:19035321080.012
neuroblast proliferationGO:000740540.012
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.012
protein importGO:00170381300.012
cellular response to external stimulusGO:00714961110.012
microtubule based processGO:00070172100.012
negative regulation of response to external stimulusGO:0032102830.012
cell chemotaxisGO:00603261120.012
tumor necrosis factor superfamily cytokine productionGO:0071706450.012
regulation of response to woundingGO:19030341010.012
negative regulation of t cell apoptotic processGO:007023340.012
engulfment of apoptotic cellGO:004365220.012
regulation of reactive oxygen species metabolic processGO:2000377410.012
purine nucleoside monophosphate metabolic processGO:00091261860.012
sensory perceptionGO:00076001030.012
response to axon injuryGO:004867810.012
atp metabolic processGO:00460341760.012
positive regulation of jnk cascadeGO:0046330520.012
myoblast fusionGO:000752010.012
inorganic ion transmembrane transportGO:00986602310.012
regulation of t cell activationGO:0050863770.012
ribonucleoside monophosphate metabolic processGO:00091611870.011
sulfur compound metabolic processGO:00067901010.011
purine ribonucleoside monophosphate metabolic processGO:00091671860.011
pattern recognition receptor signaling pathwayGO:0002221480.011
pericardium developmentGO:006003920.011
carboxylic acid biosynthetic processGO:0046394970.011
negative regulation of protein maturationGO:19033181420.011
cell divisionGO:00513011680.011
ameboidal type cell migrationGO:00016671350.011
positive regulation of cellular component biogenesisGO:00440891580.011
cytokine mediated signaling pathwayGO:00192211090.011
positive regulation of erk1 and erk2 cascadeGO:0070374750.011
Human
extrinsic apoptotic signaling pathwayGO:00971911190.011
response to bacteriumGO:00096171440.011
response to organic cyclic compoundGO:00140702040.011
taxisGO:00423301570.011
regulation of stress activated mapk cascadeGO:0032872840.011
leukocyte differentiationGO:0002521980.011
tissue migrationGO:00901301190.011
nucleoside monophosphate metabolic processGO:00091231910.011
tripartite regional subdivisionGO:000735120.011
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.011
sequestering of metal ionGO:0051238240.011
regulation of protein targetingGO:1903533910.011
organelle assemblyGO:00709251760.011
actin filament organizationGO:00070151280.011
leukocyte migrationGO:00509001070.011
regulation of mitotic cell cycleGO:00073461890.011
detection of chemical stimulusGO:0009593550.011
autophagyGO:0006914880.011
regulation of immune effector processGO:0002697910.011
regulation of meiotic cell cycleGO:005144540.011
nuclear importGO:00511701060.011
positive regulation of t cell activationGO:0050870540.011
regulation of peptidyl tyrosine phosphorylationGO:00507301080.011
response to oxidative stressGO:00069791210.011
t cell selectionGO:004505840.011
sequestering of calcium ionGO:0051208170.011
detection of stimulusGO:0051606850.011
phospholipid metabolic processGO:0006644990.011
cardiac muscle cell contractionGO:008600340.011
metencephalon developmentGO:002203720.011
glycoprotein biosynthetic processGO:0009101910.011
salivary gland morphogenesisGO:000743540.011
inflammatory responseGO:0006954790.011
positive regulation of cell cycle processGO:00900681060.011
positive regulation of cell adhesionGO:0045785840.011
regulation of jnk cascadeGO:0046328730.011
intrinsic apoptotic signaling pathwayGO:00971931270.011
neuron projection regenerationGO:003110210.011
protein localization to plasma membraneGO:0072659930.011
defense response to fungusGO:005083240.011
multicellular organismal homeostasisGO:0048871670.011
stem cell divisionGO:001714520.010
regulation of reactive oxygen species biosynthetic processGO:190342630.010
reactive nitrogen species metabolic processGO:200105730.010
associative learningGO:000830610.010
amide transportGO:0042886760.010
regulation of cell growthGO:00015581350.010
negative regulation of cell differentiationGO:00455961710.010
motor neuron axon guidanceGO:000804520.010
positive regulation of gliogenesisGO:001401540.010
negative regulation of organelle organizationGO:00106391260.010
positive regulation of cell cycleGO:00457871400.010
melanin metabolic processGO:000658210.010
response to nutrient levelsGO:0031667810.010
response to extracellular stimulusGO:0009991850.010
long term memoryGO:000761620.010
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.010

DENND2D disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.031
musculoskeletal system diseaseDOID:172230.028
immune system diseaseDOID:29141550.025
central nervous system diseaseDOID:3311860.019
nervous system diseaseDOID:8634310.019
connective tissue diseaseDOID:651090.018
inherited metabolic disorderDOID:6552420.018
disease of cellular proliferationDOID:145661740.016
cancerDOID:1621670.016
sensory system diseaseDOID:00501552030.014
organ system cancerDOID:00506861640.014
bone diseaseDOID:0080001880.014
eye diseaseDOID:56141490.012
eye and adnexa diseaseDOID:14921500.012
cardiovascular system diseaseDOID:12871060.012
acquired metabolic diseaseDOID:0060158580.011