Homo sapiens

30 known processes

PHC1

polyhomeotic homolog 1 (Drosophila)

(Aliases: RAE28,EDR1,HPH1)

PHC1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
segmentationGO:003528240.242
protein modification by small protein conjugationGO:00324463420.209
mitotic cell cycleGO:00002783260.194
Fly
chromatin modificationGO:00165682980.191
post embryonic developmentGO:000979120.158
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.139
covalent chromatin modificationGO:00165692540.121
histone modificationGO:00165702510.113
blastoderm segmentationGO:000735020.101
response to radiationGO:00093141510.088
nervous system developmentGO:00073992930.088
Fly
response to oxygen containing compoundGO:19017003690.079
Mouse Fly
response to abiotic stimulusGO:00096283360.078
regulation of cellular amine metabolic processGO:0033238110.072
chromatin organizationGO:00063253510.072
cellular component morphogenesisGO:00329893140.070
Fly
regulation of cellular amino acid metabolic processGO:000652160.065
cellular amino acid metabolic processGO:00065201160.061
regulation of apoptotic signaling pathwayGO:20012331750.061
protein acylationGO:00435431380.058
cellular ketone metabolic processGO:0042180800.058
neuron remodelingGO:001632220.057
negative regulation of cell deathGO:00605483450.056
internal protein amino acid acetylationGO:00064751010.056
cell developmentGO:00484683280.056
Fly
generation of neuronsGO:00486991520.054
Fly
wound healingGO:00420601150.053
cellular response to oxidative stressGO:0034599850.052
positive regulation of cellular amino acid metabolic processGO:004576430.052
gene silencingGO:0016458490.051
Fly
rna processingGO:00063962550.050
regulation of cell cycle processGO:00105642660.050
cellular macromolecule catabolic processGO:00442653800.050
amine metabolic processGO:0009308440.050
neuron differentiationGO:00301821380.049
Fly
protein acetylationGO:00064731160.048
neurogenesisGO:00220081690.048
Fly
positive regulation of cellular amine metabolic processGO:003324070.048
cellular amine metabolic processGO:0044106410.047
positive regulation of developmental processGO:00510943140.044
negative regulation of apoptotic processGO:00430663160.044
regulation of transferase activityGO:00513383550.043
regulation of cellular ketone metabolic processGO:0010565500.043
histone acetylationGO:0016573930.043
cell morphogenesisGO:00009022960.042
Fly
positive regulation of cell proliferationGO:00082843010.041
organ morphogenesisGO:00098871470.041
negative regulation of programmed cell deathGO:00430693210.041
determination of adult lifespanGO:000834020.041
response to oxidative stressGO:00069791210.040
cell projection organizationGO:00300302520.039
cellular response to oxygen containing compoundGO:19017012760.039
Mouse
regulation of mitotic cell cycleGO:00073461890.037
regulation of cell cycleGO:00517263930.037
positive regulation of protein phosphorylationGO:00019343130.036
embryo developmentGO:00097901230.035
Fly
multicellular organismal agingGO:001025930.035
peptidyl lysine modificationGO:00182051440.035
internal peptidyl lysine acetylationGO:0018393970.035
neuron developmentGO:00486661130.035
Fly
response to woundingGO:00096111680.035
embryonic morphogenesisGO:0048598850.034
positive regulation of phosphorylationGO:00423273940.034
matingGO:000761810.034
positive regulation of transferase activityGO:00513472270.034
chemotaxisGO:00069351570.033
negative regulation of cellular protein metabolic processGO:00322693530.033
positive regulation of cellular component organizationGO:00511303760.033
cellular macromolecular complex assemblyGO:00346223240.032
regulation of protein kinase activityGO:00458592890.032
mrna metabolic processGO:00160711750.031
pattern specification processGO:0007389430.030
negative regulation of catalytic activityGO:00430863350.029
positive regulation of protein kinase activityGO:00458601900.029
cell divisionGO:00513011680.029
neuron projection developmentGO:00311751060.028
response to organic cyclic compoundGO:00140702040.028
Fly
response to ionizing radiationGO:0010212650.028
mitotic cell cycle processGO:19030472860.028
regulation of wnt signaling pathwayGO:00301111230.027
regulation of kinase activityGO:00435493140.026
cell cycle phase transitionGO:00447701730.026
regulation of protein modification by small protein conjugation or removalGO:19033201070.026
carbohydrate metabolic processGO:00059752070.026
positive regulation of cell differentiationGO:00455972110.026
female gamete generationGO:000729220.026
Fly
regionalizationGO:0003002290.025
cell fate determinationGO:000170930.025
negative regulation of phosphorus metabolic processGO:00105632670.025
cellular protein catabolic processGO:00442572610.024
negative regulation of phosphate metabolic processGO:00459362670.024
cytoplasmic transportGO:00164823790.024
regulation of mapk cascadeGO:00434082620.024
oogenesisGO:004847720.024
Fly
hindbrain developmentGO:003090230.023
system processGO:00030083490.023
positive regulation of cell deathGO:00109422630.023
metencephalon developmentGO:002203720.023
positive regulation of immune system processGO:00026842830.023
regenerationGO:003109940.023
response to lipidGO:00339932060.022
Mouse Fly
posttranscriptional regulation of gene expressionGO:00106082130.022
leukocyte activationGO:00453211640.022
single organism carbohydrate metabolic processGO:00447231930.022
histone monoubiquitinationGO:0010390200.022
small gtpase mediated signal transductionGO:0007264780.022
protein sumoylationGO:0016925250.022
negative regulation of apoptotic signaling pathwayGO:2001234970.022
mitochondrion organizationGO:00070051560.022
regulation of neuron differentiationGO:0045664700.022
single organism cellular localizationGO:19025803320.022
cellular response to growth factor stimulusGO:00713631970.022
positive regulation of programmed cell deathGO:00430682490.022
single organism membrane organizationGO:00448022680.022
histone h2a ubiquitinationGO:0033522170.022
maintenance of locationGO:00512351120.022
regulation of cytokine productionGO:00018172320.022
regulation of cell developmentGO:00602841610.022
anterior posterior axis specificationGO:000994820.021
regulation of cellular component biogenesisGO:00440872810.021
cell morphogenesis involved in differentiationGO:00009041440.021
Fly
response to inorganic substanceGO:00100351270.021
peptidyl lysine acetylationGO:00183941010.021
immune responseGO:00069553070.021
response to ketoneGO:1901654190.021
Fly
positive regulation of cell cycleGO:00457871400.021
purine ribonucleoside metabolic processGO:00461284370.021
positive regulation of transportGO:00510503360.021
proteasomal protein catabolic processGO:00104981760.021
intracellular protein transportGO:00068862700.021
protein catabolic processGO:00301633250.021
negative regulation of protein metabolic processGO:00512483910.021
positive regulation of apoptotic processGO:00430652460.021
nuclear transportGO:00511691790.021
cellular response to endogenous stimulusGO:00714953360.021
negative regulation of cellular amine metabolic processGO:003323930.021
epithelium migrationGO:00901321190.021
positive regulation of catabolic processGO:00098963100.021
wnt signaling pathwayGO:00160551560.020
regulation of sequence specific dna binding transcription factor activityGO:00510902110.020
single organism nuclear importGO:19025931040.020
response to alcoholGO:0097305640.020
Fly
cell type specific apoptotic processGO:00972851250.020
negative regulation of cellular amino acid metabolic processGO:004576320.020
response to nitrogen compoundGO:19016981840.020
positive regulation of cellular component movementGO:00512721810.020
memoryGO:000761330.020
mrna splicing via spliceosomeGO:0000398890.020
negative regulation of protein modification processGO:00314002000.020
cell part morphogenesisGO:00329901370.020
apoptotic signaling pathwayGO:00971902680.019
proteolysis involved in cellular protein catabolic processGO:00516032440.019
embryonic epithelial tube formationGO:000183840.019
membrane organizationGO:00610242920.019
cellular response to dna damage stimulusGO:00069743790.019
taxisGO:00423301570.019
positive regulation of cellular catabolic processGO:00313312840.019
negative regulation of hydrolase activityGO:00513461820.019
locomotory behaviorGO:000762610.019
morphogenesis of embryonic epitheliumGO:001633140.019
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.019
epithelial cell proliferationGO:00506731280.019
transmembrane transportGO:00550853990.019
cell projection morphogenesisGO:00488581290.019
regulation of protein transportGO:00512232130.019
protein localization to organelleGO:00333652800.018
sex differentiationGO:0007548450.018
nucleocytoplasmic transportGO:00069131760.018
embryonic camera type eye developmentGO:003107620.018
embryonic organ morphogenesisGO:0048562240.018
nucleoside triphosphate catabolic processGO:00091433940.018
positive regulation of locomotionGO:00400171860.018
regulation of establishment of protein localizationGO:00702012420.018
positive regulation of cell cycle processGO:00900681060.018
mitotic cell cycle phase transitionGO:00447721620.018
positive regulation of hydrolase activityGO:00513453310.018
ribonucleoside triphosphate metabolic processGO:00091994120.018
negative regulation of cell differentiationGO:00455961710.017
positive regulation of epithelial cell proliferationGO:0050679650.017
negative regulation of intracellular signal transductionGO:19025321830.017
modification dependent macromolecule catabolic processGO:00436322120.017
dephosphorylationGO:00163112090.017
peptidyl tyrosine phosphorylationGO:00181081700.017
developmental process involved in reproductionGO:0003006660.017
Fly
positive regulation of cell motilityGO:20001471770.017
peptidyl tyrosine modificationGO:00182121700.017
t cell differentiation in thymusGO:003307740.017
hemopoiesisGO:00300971800.017
positive regulation of kinase activityGO:00336742040.017
protein importGO:00170381300.017
regulation of protein localizationGO:00328802960.017
negative regulation of synaptic transmissionGO:005080520.017
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.017
spinal cord developmentGO:002151040.016
ras protein signal transductionGO:0007265730.016
actin filament based processGO:00300292240.016
positive regulation of cell migrationGO:00303351720.016
chemical homeostasisGO:00488783060.016
protein localization to nucleusGO:00345041360.016
release of cytoplasmic sequestered nf kappabGO:000858840.016
rhythmic behaviorGO:000762220.016
morphogenesis of a polarized epitheliumGO:000173830.016
mapk cascadeGO:00001652880.016
negative regulation of multicellular organismal processGO:00512413170.016
regulation of cell motilityGO:20001452990.016
purine nucleoside catabolic processGO:00061523980.016
somatic stem cell maintenanceGO:003501940.016
purine nucleoside triphosphate metabolic processGO:00091444120.016
cellular response to hormone stimulusGO:00328701250.016
cell projection assemblyGO:00300311260.016
regulation of mitotic cell cycle phase transitionGO:19019901180.016
rna splicingGO:00083801310.016
purine nucleoside triphosphate catabolic processGO:00091463920.016
protein ubiquitinationGO:00165673140.015
regulation of cell migrationGO:00303342890.015
neuromuscular junction developmentGO:000752830.015
chromatin remodelingGO:0006338550.015
neuroblast proliferationGO:000740540.015
regulation of cell cycle phase transitionGO:19019871260.015
vesicle mediated transportGO:00161923710.015
negative regulation of phosphorylationGO:00423261740.015
cellular protein complex assemblyGO:00436231880.015
reproductive processGO:00224141060.015
Fly
axon regenerationGO:003110310.015
response to hormoneGO:00097251750.015
negative regulation of cell proliferationGO:00082852280.015
nucleoside phosphate catabolic processGO:19012924120.015
establishment of protein localization to organelleGO:00725941720.015
intrinsic apoptotic signaling pathwayGO:00971931270.015
g1 s transition of mitotic cell cycleGO:0000082780.015
regulation of cellular component movementGO:00512703340.015
purine containing compound catabolic processGO:00725234110.015
regulation of cell growthGO:00015581350.015
stem cell divisionGO:001714520.015
positive regulation of transcription from rna polymerase ii promoter during mitosisGO:004602210.015
pituitary gland developmentGO:002198320.015
positive regulation of organelle organizationGO:00106381950.015
glycosyl compound catabolic processGO:19016584130.015
regulation of epithelial cell proliferationGO:00506781130.014
neurological system processGO:00508771630.014
regulation of protein catabolic processGO:00421761550.014
nucleotide catabolic processGO:00091664080.014
regulation of cell projection organizationGO:00313441070.014
regulation of cell differentiationGO:00455953930.014
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.014
regulation of proteolysisGO:00301622930.014
skeletal system developmentGO:0001501790.014
cell cycle g1 s phase transitionGO:0044843800.014
regulation of neural precursor cell proliferationGO:200017740.014
reactive oxygen species metabolic processGO:0072593750.014
response to acid chemicalGO:0001101660.014
Mouse
ribonucleotide catabolic processGO:00092614050.014
regulation of nucleotide metabolic processGO:00061402690.014
developmental maturationGO:0021700280.014
response to organonitrogen compoundGO:00102431560.014
metal ion transportGO:00300012720.014
regulation of protein stabilityGO:0031647870.014
regulation of reactive oxygen species metabolic processGO:2000377410.014
regulation of locomotionGO:00400123290.014
motor neuron axon guidanceGO:000804520.014
digestive tract developmentGO:0048565750.014
regulation of transcription during mitosisGO:004589620.014
regulation of i kappab kinase nf kappab signalingGO:00431221620.014
spermatid differentiationGO:004851540.014
rostrocaudal neural tube patterningGO:002190310.014
ubiquitin dependent protein catabolic processGO:00065112060.014
regulation of transcription from rna polymerase ii promoter mitoticGO:004602110.014
response to axon injuryGO:004867810.014
regulation of cell cycle arrestGO:0071156360.014
regulation of peptidase activityGO:00525471800.014
reactive oxygen species biosynthetic processGO:190340940.014
regulation of protein complex assemblyGO:00432541470.013
negative regulation of cell cycle processGO:00109481210.013
associative learningGO:000830610.013
cytokine productionGO:00018162470.013
oocyte differentiationGO:000999420.013
regulation of anatomical structure morphogenesisGO:00226032860.013
cell cycle checkpointGO:00000751170.013
photoreceptor cell differentiationGO:004653020.013
positive regulation of nucleoside metabolic processGO:00459791860.013
innate immune responseGO:00450871780.013
regulation of endopeptidase activityGO:00525481700.013
regulation of synaptic plasticityGO:004816730.013
positive regulation of transcription during mitosisGO:004589720.013
ameboidal type cell migrationGO:00016671350.013
regulation of cytoskeleton organizationGO:00514931770.013
carbohydrate derivative biosynthetic processGO:19011372070.013
negative regulation of growthGO:0045926970.013
lymphocyte activationGO:00466491330.013
ribonucleoside triphosphate catabolic processGO:00092033910.013
signal transduction by phosphorylationGO:00230142970.013
cellular response to organonitrogen compoundGO:00714171240.013
tube developmentGO:00352951250.013
cellular lipid metabolic processGO:00442553030.013
cell junction organizationGO:0034330790.013
positive regulation of purine nucleotide metabolic processGO:19005442270.013
rho protein signal transductionGO:0007266260.013
cardiac muscle cell contractionGO:008600340.013
organelle assemblyGO:00709251760.013
secretion by cellGO:00329402260.013
regulation of reactive oxygen species biosynthetic processGO:190342630.013
negative regulation of cellular component movementGO:00512711060.013
regulation of cellular response to stressGO:00801352440.013
somatic muscle developmentGO:000752510.013
oocyte developmentGO:004859910.013
protein targetingGO:00066051870.013
endodermal cell fate specificationGO:000171440.013
negative regulation of cell cycleGO:00457861930.013
ribonucleoside catabolic processGO:00424544060.013
negative regulation of cellular component organizationGO:00511292350.013
nitrogen compound transportGO:00717051910.013
central nervous system developmentGO:00074171230.013
Fly
purine ribonucleoside triphosphate catabolic processGO:00092073910.013
positive regulation of protein serine threonine kinase activityGO:00719021190.013
regulation of purine nucleotide metabolic processGO:19005422640.013
regulation of growthGO:00400081650.013
cell adhesionGO:00071553250.013
embryonic organ developmentGO:0048568360.013
anatomical structure formation involved in morphogenesisGO:00486462840.012
Fly
positive regulation of cell developmentGO:0010720920.012
long term memoryGO:000761620.012
mrna processingGO:00063971330.012
negative regulation of protein phosphorylationGO:00019331400.012
positive regulation of mapk cascadeGO:00434101900.012
organophosphate catabolic processGO:00464344300.012
positive regulation of purine nucleotide catabolic processGO:00331231850.012
regulation of secretion by cellGO:19035301770.012
response to cytokineGO:00340972320.012
protein deubiquitinationGO:0016579790.012
endothelial cell migrationGO:0043542860.012
reactive nitrogen species metabolic processGO:200105730.012
protein oligomerizationGO:00512591730.012
protein targeting to nucleusGO:00447441040.012
circadian behaviorGO:004851220.012
histone h2a monoubiquitinationGO:0035518110.012
response to drugGO:0042493810.012
lymphocyte proliferationGO:0046651700.012
regulation of neurogenesisGO:0050767820.012
spermatid developmentGO:000728640.012
regulation of ras protein signal transductionGO:00465781550.012
lipid metabolic processGO:00066293810.012
neural crest cell developmentGO:001403230.012
positive regulation of nucleotide metabolic processGO:00459812300.012
guanosine containing compound catabolic processGO:19010692390.012
growthGO:00400072020.012
negative regulation of kinase activityGO:00336731060.012
response to external biotic stimulusGO:00432072610.012
epithelial cell migrationGO:00106311190.012
regulation of dephosphorylationGO:0035303960.012
negative regulation of cell adhesionGO:0007162640.012
i kappab kinase nf kappab signalingGO:00072491660.012
head developmentGO:00603221080.012
regulation of leukocyte activationGO:00026941150.012
protein maturationGO:00516042330.012
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.012
primary neural tube formationGO:001402030.012
regulation of intracellular protein transportGO:00331571230.012
somitogenesisGO:000175620.012
canonical wnt signaling pathwayGO:00600701160.012
negative regulation of transportGO:00510511760.012
tissue morphogenesisGO:0048729960.012
Fly
embryonic camera type eye morphogenesisGO:004859620.011
cellular carbohydrate metabolic processGO:0044262840.011
nucleoside catabolic processGO:00091644080.011
nuclear divisionGO:00002801280.011
rna interferenceGO:001624640.011
positive regulation of reactive oxygen species biosynthetic processGO:190342820.011
development of primary sexual characteristicsGO:0045137350.011
response to reactive oxygen speciesGO:0000302610.011
biological adhesionGO:00226103310.011
startle responseGO:000196430.011
gtp metabolic processGO:00460392390.011
cell activationGO:00017752130.011
ribonucleoprotein complex biogenesisGO:00226131160.011
positive regulation of reactive oxygen species metabolic processGO:2000379240.011
regulation of intracellular transportGO:00323861950.011
cellular response to cytokine stimulusGO:00713451810.011
neuron fate commitmentGO:004866320.011
melanin metabolic processGO:000658210.011
sensory perceptionGO:00076001030.011
cellular response to hydrogen peroxideGO:0070301370.011
monocarboxylic acid metabolic processGO:00327871850.011
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.011
compound eye developmentGO:004874910.011
purine ribonucleoside catabolic processGO:00461303980.011
response to biotic stimulusGO:00096072760.011
protein import into nucleusGO:00066061040.011
regulation of epithelial cell migrationGO:0010632930.011
neurotransmitter secretionGO:000726940.011
prostate gland developmentGO:003085030.011
sex determinationGO:000753030.011
ion transmembrane transportGO:00342203380.011
neuron projection regenerationGO:003110210.011
positive regulation of cellular component biogenesisGO:00440891580.011
histone ubiquitinationGO:0016574310.011
cilium morphogenesisGO:0060271750.011
cellular homeostasisGO:00197251960.011
regulation of gene expression epigeneticGO:0040029730.011
neuron projection morphogenesisGO:0048812500.011
anterior posterior axis specification embryoGO:000859520.011
endomembrane system organizationGO:00102561960.011
regulation of cell divisionGO:00513021160.011
modification dependent protein catabolic processGO:00199412090.011
regulation of nucleotide catabolic processGO:00308112050.011
microtubule cytoskeleton organizationGO:00002261760.011
multi organism cellular processGO:00447641560.011
enzyme linked receptor protein signaling pathwayGO:00071673030.011
regulation of meiotic cell cycleGO:005144540.011
epithelium developmentGO:00604292270.011
Fly
purine nucleotide catabolic processGO:00061954050.011
adult locomotory behaviorGO:000834410.011
negative regulation of cell migrationGO:00303361020.011
regulation of feeding behaviorGO:006025930.011
negative regulation of cell motilityGO:20001461040.011
regulation of secretionGO:00510461940.011
male genitalia developmentGO:003053910.010
dna damage checkpointGO:0000077680.010
cation transportGO:00068123310.010
response to fungusGO:000962040.010
regulation of nucleoside metabolic processGO:00091182090.010
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377890.010
glycoprotein metabolic processGO:00091001100.010
negative regulation of cell growthGO:0030308830.010
inner ear morphogenesisGO:004247240.010
regulation of protein serine threonine kinase activityGO:00719001790.010
negative regulation of transferase activityGO:00513481240.010
regulation of cysteine type endopeptidase activityGO:20001161270.010
regulation of peptidyl tyrosine phosphorylationGO:00507301080.010
regulation of purine nucleotide catabolic processGO:00331212050.010
positive regulation of mitotic cell cycleGO:0045931600.010
epithelial cell differentiationGO:00308551410.010
Fly
purine ribonucleoside triphosphate metabolic processGO:00092054110.010
positive regulation of secretionGO:00510471160.010
regulation of cellular response to growth factor stimulusGO:0090287760.010
regulation of glial cell proliferationGO:006025140.010
limbic system developmentGO:002176130.010
single organism reproductive processGO:0044702980.010
Fly
positive regulation of protein transportGO:00512221350.010
positive regulation of synaptic transmissionGO:005080640.010
cellular response to lipidGO:00713961270.010
Mouse
cation transmembrane transportGO:00986552380.010
regulation of protein maturationGO:19033171500.010
negative regulation of intracellular transportGO:0032387600.010
response to other organismGO:00517072610.010
hematopoietic or lymphoid organ developmentGO:00485341860.010
nuclear importGO:00511701060.010
regulation of lymphocyte activationGO:00512491030.010
syncytium formation by plasma membrane fusionGO:000076820.010
tube closureGO:006060630.010
regulation of axon guidanceGO:190266730.010

PHC1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.020
sensory system diseaseDOID:00501552030.020
central nervous system diseaseDOID:3311860.017
disease of metabolismDOID:00146672950.016
disease of cellular proliferationDOID:145661740.015
eye and adnexa diseaseDOID:14921500.015
musculoskeletal system diseaseDOID:172230.014
eye diseaseDOID:56141490.013
cancerDOID:1621670.013
inherited metabolic disorderDOID:6552420.012
organ system cancerDOID:00506861640.012
neurodegenerative diseaseDOID:12891020.010