Homo sapiens

123 known processes

THOC4

THO complex 4

(Aliases: REF,BEF,ALY/REF,ALY)

THOC4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
intracellular transport of virusGO:0075733141.000
multi organism intracellular transportGO:1902583141.000
mrna export from nucleusGO:0006406291.000
mrna transportGO:0051028301.000
multi organism localizationGO:1902579141.000
nucleobase containing compound transportGO:0015931511.000
rna export from nucleusGO:0006405331.000
rna transportGO:0050658391.000
viral processGO:00160321461.000
nucleic acid transportGO:0050657391.000
establishment of rna localizationGO:0051236391.000
multi organism transportGO:0044766141.000
positive regulation of dna templated transcription elongationGO:0032786181.000
transport of virusGO:0046794141.000
viral life cycleGO:00190581321.000
viral mrna export from host cell nucleusGO:004678481.000
nuclear exportGO:0051168691.000
rna localizationGO:0006403411.000
cytoplasmic transportGO:00164823791.000
symbiosis encompassing mutualism through parasitismGO:00444031561.000
multi organism cellular processGO:00447641560.999
interspecies interaction between organismsGO:00444191560.999
nitrogen compound transportGO:00717051910.999
nuclear transportGO:00511691790.998
mrna metabolic processGO:00160711750.997
regulation of dna templated transcription elongationGO:0032784230.995
purine nucleoside monophosphate metabolic processGO:00091261860.993
Yeast
ribonucleoside monophosphate catabolic processGO:00091581580.991
Yeast
nucleoside monophosphate catabolic processGO:00091251590.988
Yeast
dna damage checkpointGO:0000077680.980
mrna 3 end processingGO:0031124240.976
replication fork processingGO:0031297130.975
ribonucleoside catabolic processGO:00424544060.975
Yeast
negative regulation of cell cycle checkpointGO:190197740.961
mrna processingGO:00063971330.960
purine nucleoside catabolic processGO:00061523980.959
Yeast
glycosyl compound catabolic processGO:19016584130.958
Yeast
purine ribonucleotide catabolic processGO:00091544040.948
Yeast
nucleocytoplasmic transportGO:00069131760.947
nucleoside phosphate catabolic processGO:19012924120.943
Yeast
atp catabolic processGO:00062001570.930
Yeast
regulation of dna damage checkpointGO:200000190.930
nucleoside catabolic processGO:00091644080.916
Yeast
dna templated transcription elongationGO:0006354250.913
rna catabolic processGO:0006401710.912
cellular response to dna damage stimulusGO:00069743790.909
nucleoside monophosphate metabolic processGO:00091231910.899
Yeast
negative regulation of dna damage checkpointGO:200000240.885
nucleotide catabolic processGO:00091664080.885
Yeast
rna processingGO:00063962550.875
dna integrity checkpointGO:0031570710.865
nuclear transcribed mrna catabolic processGO:0000956480.860
mrna splicing via spliceosomeGO:0000398890.860
purine ribonucleoside catabolic processGO:00461303980.836
Yeast
regulation of atpase activityGO:0043462250.835
Yeast
purine nucleoside triphosphate catabolic processGO:00091463920.834
Yeast
mrna catabolic processGO:0006402560.832
organophosphate catabolic processGO:00464344300.826
Yeast
purine ribonucleoside metabolic processGO:00461284370.817
Yeast
rna 3 end processingGO:0031123350.815
rna splicing via transesterification reactionsGO:0000375900.813
primary mirna processingGO:003105330.798
cell cycle checkpointGO:00000751170.788
purine ribonucleoside triphosphate metabolic processGO:00092054110.766
Yeast
ribonucleoside triphosphate catabolic processGO:00092033910.761
Yeast
post embryonic developmentGO:000979120.756
nucleotide excision repairGO:0006289310.755
Yeast
purine containing compound catabolic processGO:00725234110.754
Yeast
purine ribonucleoside monophosphate catabolic processGO:00091691580.741
Yeast
purine nucleoside monophosphate catabolic processGO:00091281580.736
Yeast
dna recombinationGO:0006310770.730
nucleoside triphosphate catabolic processGO:00091433940.716
Yeast
regulation of cellular response to stressGO:00801352440.707
regulation of atp metabolic processGO:1903578290.692
Yeast
dna repairGO:00062811980.692
Yeast
translationGO:00064121320.682
Human
spliceosomal complex assemblyGO:0000245170.679
regulation of nucleoside metabolic processGO:00091182090.674
Yeast
purine ribonucleoside monophosphate metabolic processGO:00091671860.667
Yeast
regulation of atp catabolic processGO:1903289250.666
Yeast
atp metabolic processGO:00460341760.656
Yeast
purine ribonucleoside triphosphate catabolic processGO:00092073910.651
Yeast
female gamete generationGO:000729220.643
negative regulation of cell cycle processGO:00109481210.577
regulation of mrna metabolic processGO:1903311530.563
negative regulation of apoptotic processGO:00430663160.561
regulation of response to dna damage stimulusGO:2001020940.539
positive regulation of nucleotide metabolic processGO:00459812300.532
chromatin organizationGO:00063253510.530
negative regulation of cell cycleGO:00457861930.522
regulation of rna splicingGO:0043484620.506
oogenesisGO:004847720.501
ribonucleoside triphosphate metabolic processGO:00091994120.493
Yeast
response to abiotic stimulusGO:00096283360.489
nucleoside triphosphate metabolic processGO:00091414220.455
Yeast
regulation of cell cycle processGO:00105642660.450
nuclear transcribed mrna catabolic process nonsense mediated decayGO:0000184230.440
regulation of purine nucleotide metabolic processGO:19005422640.426
Yeast
regulation of purine nucleotide catabolic processGO:00331212050.426
Yeast
purine nucleotide catabolic processGO:00061954050.421
Yeast
purine nucleoside triphosphate metabolic processGO:00091444120.396
Yeast
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377890.394
organelle fissionGO:00482851490.389
negative regulation of immune responseGO:0050777400.376
nuclear divisionGO:00002801280.349
regulation of translationGO:0006417890.338
Human
negative regulation of response to dna damage stimulusGO:2001021330.333
regulation of cell cycleGO:00517263930.328
ribonucleotide catabolic processGO:00092614050.269
Yeast
regulation of mrna splicing via spliceosomeGO:0048024320.266
response to organic cyclic compoundGO:00140702040.248
immune system developmentGO:00025201950.231
immune effector processGO:00022521590.216
alternative mrna splicing via spliceosomeGO:0000380270.206
negative regulation of immunoglobulin mediated immune responseGO:000289030.200
negative regulation of immune system processGO:00026831360.197
reproductive system developmentGO:0061458560.196
positive regulation of nucleotide catabolic processGO:00308131850.191
myeloid cell differentiationGO:00300991170.188
ras protein signal transductionGO:0007265730.185
transcription coupled nucleotide excision repairGO:000628380.181
Yeast
segmentationGO:003528240.179
rna splicingGO:00083801310.171
positive regulation of catabolic processGO:00098963100.169
microtubule cytoskeleton organizationGO:00002261760.168
regulation of meiosisGO:004002030.160
embryo developmentGO:00097901230.159
regulation of dna recombinationGO:0000018230.157
regulation of meiotic cell cycleGO:005144540.150
positive regulation of purine nucleotide catabolic processGO:00331231850.150
negative regulation of viral processGO:0048525660.150
ribonucleoside monophosphate metabolic processGO:00091611870.146
Yeast
transcription elongation from rna polymerase ii promoterGO:0006368180.139
positive regulation of hydrolase activityGO:00513453310.139
single organism reproductive processGO:0044702980.138
cellular macromolecular complex assemblyGO:00346223240.137
regulation of multi organism processGO:00439001570.133
chromatin silencingGO:0006342120.132
negative regulation of programmed cell deathGO:00430693210.126
negative regulation of gene expression epigeneticGO:0045814190.124
ribonucleoprotein complex assemblyGO:0022618780.120
regulation of b cell activationGO:0050864240.113
positive regulation of nucleoside metabolic processGO:00459791860.110
positive regulation of purine nucleotide metabolic processGO:19005442270.109
viral genome replicationGO:0019079500.106
reproductive processGO:00224141060.106
regulation of cell developmentGO:00602841610.105
chromosome segregationGO:00070591140.102
intracellular mrna localizationGO:000829810.099
gonad developmentGO:0008406340.098
hematopoietic or lymphoid organ developmentGO:00485341860.095
negative regulation of viral genome replicationGO:0045071350.095
regulation of immune responseGO:00507762010.091
anterior posterior axis specification embryoGO:000859520.089
cellular macromolecule catabolic processGO:00442653800.085
lymphocyte mediated immunityGO:0002449480.085
regulation of viral processGO:00507921030.085
sex differentiationGO:0007548450.085
b cell activationGO:0042113330.084
negative regulation of b cell mediated immunityGO:000271330.084
mitotic cell cycle processGO:19030472860.084
regulation of cell cycle checkpointGO:1901976210.083
regulation of gene expression epigeneticGO:0040029730.077
anterior posterior axis specificationGO:000994820.076
positive regulation of atpase activityGO:0032781190.074
regulation of viral genome replicationGO:0045069480.073
regulation of cell activationGO:00508651250.071
oocyte differentiationGO:000999420.068
oocyte developmentGO:004859910.068
developmental process involved in reproductionGO:0003006660.067
meiotic chromosome segregationGO:004513240.063
production of sirna involved in rna interferenceGO:003042230.061
negative regulation of cellular protein metabolic processGO:00322693530.060
rna cappingGO:0036260100.059
immune responseGO:00069553070.058
membrane organizationGO:00610242920.057
chromatin remodelingGO:0006338550.057
protein ubiquitinationGO:00165673140.056
negative regulation of protein metabolic processGO:00512483910.056
blastoderm segmentationGO:000735020.055
single organism cellular localizationGO:19025803320.054
regulation of cell cycle phase transitionGO:19019871260.053
positive regulation of cellular catabolic processGO:00313312840.053
tripartite regional subdivisionGO:000735120.052
negative regulation of translationGO:0017148370.051
protein complex disassemblyGO:0043241520.051
cell activationGO:00017752130.049
regulation of alternative mrna splicing via spliceosomeGO:0000381220.049
mitotic cell cycleGO:00002783260.049
regulation of immune effector processGO:0002697910.048
cellular lipid metabolic processGO:00442553030.047
negative regulation of production of molecular mediator of immune responseGO:0002701130.045
positive regulation of atp catabolic processGO:1903291190.045
negative regulation of multicellular organismal processGO:00512413170.045
lymphocyte activation involved in immune responseGO:0002285200.045
determination of adult lifespanGO:000834020.045
ribonucleoprotein complex subunit organizationGO:0071826810.044
chromatin modificationGO:00165682980.043
gene silencingGO:0016458490.043
protein importGO:00170381300.043
nucleus localizationGO:005164710.042
leukocyte mediated immunityGO:0002443590.042
gtp metabolic processGO:00460392390.041
somatic recombination of immunoglobulin gene segmentsGO:001644740.040
regulation of cell divisionGO:00513021160.039
macromolecular complex disassemblyGO:0032984600.039
reproductive structure developmentGO:0048608550.039
single organism membrane organizationGO:00448022680.037
establishment of nucleus localizationGO:004002310.037
regulation of endopeptidase activityGO:00525481700.037
regulation of leukocyte mediated immunityGO:0002703380.037
embryo development ending in birth or egg hatchingGO:0009792340.037
dna replicationGO:00062601160.037
regulation of proteolysisGO:00301622930.036
development of primary sexual characteristicsGO:0045137350.035
regulation of oocyte developmentGO:006028110.035
regulation of cellular component biogenesisGO:00440872810.035
positive regulation of intracellular protein transportGO:0090316760.035
dephosphorylationGO:00163112090.035
regulation of leukocyte activationGO:00026941150.034
regulation of nuclear divisionGO:0051783650.034
response to nitrogen compoundGO:19016981840.033
protein localization to organelleGO:00333652800.032
negative regulation of hydrolase activityGO:00513461820.032
Yeast
regulation of mitotic cell cycleGO:00073461890.031
regulation of mrna processingGO:0050684480.031
cellular response to oxygen containing compoundGO:19017012760.031
small gtpase mediated signal transductionGO:0007264780.031
enzyme linked receptor protein signaling pathwayGO:00071673030.031
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.031
response to oxygen containing compoundGO:19017003690.030
mitochondrial transportGO:0006839600.030
microtubule based processGO:00070172100.030
regulation of isotype switchingGO:004519120.030
positive regulation of translationGO:0045727350.030
Human
response to biotic stimulusGO:00096072760.029
regulation of nucleotide catabolic processGO:00308112050.029
Yeast
7 methylguanosine rna cappingGO:000945290.029
isotype switchingGO:004519030.029
innate immune responseGO:00450871780.028
regulation of cell maturationGO:190342930.028
regulation of lymphocyte activationGO:00512491030.027
regulation of myeloid cell differentiationGO:0045637810.027
locomotory behaviorGO:000762610.026
negative regulation of cellular component organizationGO:00511292350.026
gtp catabolic processGO:00061842370.026
meiotic cell cycleGO:0051321130.026
histone modificationGO:00165702510.025
intracellular protein transportGO:00068862700.023
regulation of lymphocyte mediated immunityGO:0002706330.023
establishment of organelle localizationGO:0051656590.023
somatic cell dna recombinationGO:001644460.023
engulfment of apoptotic cellGO:004365220.022
leukocyte activation involved in immune responseGO:0002366300.022
nuclear migrationGO:000709710.022
mrna cis splicing via spliceosomeGO:004529270.021
defense responseGO:00069523150.021
positive regulation of mapk cascadeGO:00434101900.021
epithelium developmentGO:00604292270.021
establishment of protein localization to organelleGO:00725941720.021
cardiovascular system developmentGO:00723582620.021
guanosine containing compound catabolic processGO:19010692390.021
cellular response to organic cyclic compoundGO:00714071270.021
negative regulation of catalytic activityGO:00430863350.021
Yeast
lymphocyte activationGO:00466491330.020
hemopoiesisGO:00300971800.020
cellular protein complex disassemblyGO:0043624360.020
response to temperature stimulusGO:0009266220.020
negative regulation of developmental processGO:00510932470.020
negative regulation of mitotic cell cycleGO:00459301020.020
multicellular organismal reproductive processGO:0048609400.020
negative regulation of cell deathGO:00605483450.019
reproductionGO:0000003630.019
Worm
7 methylguanosine mrna cappingGO:000637070.019
positive regulation of transportGO:00510503360.018
negative regulation of b cell activationGO:005086960.018
response to external biotic stimulusGO:00432072610.018
positive regulation of cell proliferationGO:00082843010.018
regulation of synaptic plasticityGO:004816730.018
establishment or maintenance of cytoskeleton polarityGO:003095230.018
lipid metabolic processGO:00066293810.018
generation of neuronsGO:00486991520.018
multi organism reproductive processGO:0044703540.017
protein localization to nucleusGO:00345041360.017
cation transportGO:00068123310.017
isotype switching to iga isotypesGO:004829020.017
protein complex localizationGO:0031503310.017
leukocyte differentiationGO:0002521980.017
ncrna processingGO:0034470830.017
response to other organismGO:00517072610.016
regionalizationGO:0003002290.016
anatomical structure formation involved in morphogenesisGO:00486462840.016
regulation of gtp catabolic processGO:00331241800.016
central nervous system developmentGO:00074171230.016
adaptive immune responseGO:0002250490.016
ubiquitin dependent protein catabolic processGO:00065112060.016
taxisGO:00423301570.016
vesicle mediated transportGO:00161923710.016
regulation of growthGO:00400081650.016
dna dependent dna replicationGO:0006261440.015
negative regulation of multi organism processGO:0043901920.015
transmembrane transportGO:00550853990.015
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822290.015
regulation of adaptive immune responseGO:0002819330.015
organic hydroxy compound metabolic processGO:19016151470.015
negative regulation of cell cycle phase transitionGO:1901988890.015
protein targetingGO:00066051870.015
negative regulation of intracellular signal transductionGO:19025321830.015
regulation of peptidase activityGO:00525471800.015
cellular response to hypoxiaGO:0071456510.015
negative regulation of cell differentiationGO:00455961710.015
cell developmentGO:00484683280.015
glycerolipid metabolic processGO:00464861070.015
response to decreased oxygen levelsGO:0036293960.015
response to hormoneGO:00097251750.014
regulation of protein maturationGO:19033171500.014
protein maturationGO:00516042330.014
endocytosisGO:00068971590.014
regulation of isotype switching to iga isotypesGO:004829620.014
lipid catabolic processGO:0016042840.014
negative regulation of apoptotic signaling pathwayGO:2001234970.014
regulation of cell differentiationGO:00455953930.014
response to hypoxiaGO:0001666960.014
secretionGO:00469032540.014
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.014
positive regulation of growthGO:0045927580.013
positive regulation of developmental growthGO:0048639160.013
posttranscriptional regulation of gene expressionGO:00106082130.013
Human
regulation of intracellular protein transportGO:00331571230.013
regulation of ligase activityGO:0051340290.013
regulation of protein localizationGO:00328802960.013
inflammatory responseGO:0006954790.013
positive regulation of atp metabolic processGO:1903580200.013
cellular response to nitrogen compoundGO:19016991440.013
cilium organizationGO:0044782680.013
stem cell developmentGO:0048864690.012
protein k11 linked ubiquitinationGO:0070979240.012
regulation of ras protein signal transductionGO:00465781550.012
positive regulation of ras gtpase activityGO:00323201170.012
actin filament based processGO:00300292240.012
regulation of apoptotic signaling pathwayGO:20012331750.012
protein processingGO:00164852260.012
biological adhesionGO:00226103310.012
cellular protein catabolic processGO:00442572610.012
regulation of cysteine type endopeptidase activityGO:20001161270.012
cell adhesionGO:00071553250.011
regulation of small gtpase mediated signal transductionGO:00510561560.011
metal ion transportGO:00300012720.011
chemical homeostasisGO:00488783060.011
mitotic spindle organizationGO:0007052270.011
negative regulation of leukocyte mediated immunityGO:0002704140.011
rna interferenceGO:001624640.011
positive regulation of programmed cell deathGO:00430682490.011
nuclear mrna surveillanceGO:007102840.011
positive regulation of erk1 and erk2 cascadeGO:0070374750.011
sexual reproductionGO:0019953370.011
phospholipid metabolic processGO:0006644990.011
macromolecule methylationGO:0043414970.011
apoptotic mitochondrial changesGO:0008637570.011
spermatid differentiationGO:004851540.011
regulation of protein modification by small protein conjugation or removalGO:19033201070.011
secretion by cellGO:00329402260.011
mapk cascadeGO:00001652880.011
sex determinationGO:000753030.011
rna secondary structure unwindingGO:001050130.010
negative regulation of mitotic cell cycle phase transitionGO:1901991850.010
gamete generationGO:0007276250.010
covalent chromatin modificationGO:00165692540.010
adult locomotory behaviorGO:000834410.010
muscle system processGO:0003012810.010
positive regulation of developmental processGO:00510943140.010
nucleosome assemblyGO:0006334500.010

THOC4 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:00506861640.015
disease of cellular proliferationDOID:145661740.015
cancerDOID:1621670.015
disease of mental healthDOID:150700.010
central nervous system diseaseDOID:3311860.010
nervous system diseaseDOID:8634310.010