Homo sapiens

141 known processes

RNF8

ring finger protein 8

(Aliases: FLJ12013,KIAA0646)

RNF8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chromatin organizationGO:00063253510.389
histone modificationGO:00165702510.343
protein catabolic processGO:00301633250.214
protein ubiquitinationGO:00165673140.210
methylationGO:00322591060.207
modification dependent macromolecule catabolic processGO:00436322120.201
proteolysis involved in cellular protein catabolic processGO:00516032440.177
histone methylationGO:0016571600.175
chromatin modificationGO:00165682980.148
protein polyubiquitinationGO:00002091100.144
cellular response to dna damage stimulusGO:00069743790.141
macromolecule methylationGO:0043414970.125
negative regulation of cell deathGO:00605483450.117
histone lysine methylationGO:0034968500.112
protein methylationGO:0006479740.107
protein modification by small protein conjugationGO:00324463420.085
protein alkylationGO:0008213740.085
cellular protein catabolic processGO:00442572610.081
positive regulation of developmental processGO:00510943140.078
embryonic digestive tract morphogenesisGO:004855720.073
positive regulation of cellular component organizationGO:00511303760.069
regulation of cell cycleGO:00517263930.067
Human
response to abiotic stimulusGO:00096283360.065
growthGO:00400072020.064
ras protein signal transductionGO:0007265730.062
protein localization to organelleGO:00333652800.060
immune responseGO:00069553070.059
regulation of cell cycle processGO:00105642660.059
Human
regulation of proteolysisGO:00301622930.059
cell fate determinationGO:000170930.059
small gtpase mediated signal transductionGO:0007264780.058
negative regulation of apoptotic processGO:00430663160.058
regulation of response to dna damage stimulusGO:2001020940.057
regenerationGO:003109940.055
locomotory behaviorGO:000762610.054
proteasomal protein catabolic processGO:00104981760.054
actin filament based processGO:00300292240.053
adult locomotory behaviorGO:000834410.050
covalent chromatin modificationGO:00165692540.050
regulation of dna repairGO:0006282470.048
i kappab kinase nf kappab signalingGO:00072491660.048
regulation of kinase activityGO:00435493140.048
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.047
signal transduction in response to dna damageGO:0042770570.047
regulation of establishment of protein localizationGO:00702012420.046
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.046
secretionGO:00469032540.045
negative regulation of programmed cell deathGO:00430693210.044
meiotic chromosome segregationGO:004513240.044
positive regulation of transportGO:00510503360.043
cellular lipid metabolic processGO:00442553030.042
regulation of mitotic cell cycleGO:00073461890.041
Human
positive regulation of phosphorylationGO:00423273940.041
cellular macromolecule catabolic processGO:00442653800.039
g2 m transition of mitotic cell cycleGO:0000086410.038
regulation of ras protein signal transductionGO:00465781550.038
release of cytoplasmic sequestered nf kappabGO:000858840.037
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.037
positive regulation of transferase activityGO:00513472270.037
negative regulation of protein maturationGO:19033181420.036
tissue regenerationGO:004224630.035
protein targetingGO:00066051870.035
organelle assemblyGO:00709251760.035
positive regulation of programmed cell deathGO:00430682490.034
response to ionizing radiationGO:0010212650.034
positive regulation of dna repairGO:0045739250.034
system processGO:00030083490.034
mitotic cell cycleGO:00002783260.033
Human
regulation of protein localizationGO:00328802960.033
positive regulation of cell cycleGO:00457871400.033
protein maturationGO:00516042330.032
positive regulation of proteolysisGO:00458621420.031
regulation of cell differentiationGO:00455953930.031
intracellular protein transportGO:00068862700.031
somatic diversification of immunoglobulins involved in immune responseGO:000220830.031
reactive oxygen species biosynthetic processGO:190340940.031
regulation of small gtpase mediated signal transductionGO:00510561560.031
immune effector processGO:00022521590.030
positive regulation of cellular amine metabolic processGO:003324070.030
dna catabolic process exonucleolyticGO:0000738170.029
membrane organizationGO:00610242920.029
digestive system developmentGO:0055123750.029
positive regulation of cellular component biogenesisGO:00440891580.029
regulation of anatomical structure morphogenesisGO:00226032860.028
single organism cellular localizationGO:19025803320.028
regulation of i kappab kinase nf kappab signalingGO:00431221620.028
negative regulation of immune system processGO:00026831360.028
neuromuscular junction developmentGO:000752830.027
microtubule cytoskeleton organizationGO:00002261760.027
positive regulation of catabolic processGO:00098963100.027
lipid metabolic processGO:00066293810.026
cellular amino acid metabolic processGO:00065201160.026
protein deubiquitinationGO:0016579790.026
regulation of protein autophosphorylationGO:0031952150.026
regulation of cellular response to stressGO:00801352440.026
regulation of protein complex assemblyGO:00432541470.026
positive regulation of cellular amino acid metabolic processGO:004576430.026
cell cycle checkpointGO:00000751170.026
Human
reactive nitrogen species metabolic processGO:200105730.026
regulation of protein catabolic processGO:00421761550.025
negative regulation of transportGO:00510511760.025
mitochondrion organizationGO:00070051560.024
regulation of protein transportGO:00512232130.024
double strand break repairGO:00063021010.024
negative regulation of developmental processGO:00510932470.024
regulation of intracellular transportGO:00323861950.024
negative regulation of catalytic activityGO:00430863350.024
dna double strand break processingGO:0000729100.024
defense responseGO:00069523150.024
actin filament based movementGO:0030048170.024
lipid biosynthetic processGO:00086101770.024
cellular response to abiotic stimulusGO:00712141170.023
cytoplasmic transportGO:00164823790.023
dna templated transcription initiationGO:0006352350.023
morphogenesis of embryonic epitheliumGO:001633140.023
positive regulation of transcription initiation from rna polymerase ii promoterGO:006026140.023
small molecule biosynthetic processGO:00442831570.023
regulation of protein modification by small protein conjugation or removalGO:19033201070.023
negative regulation of phosphate metabolic processGO:00459362670.022
regulation of immune responseGO:00507762010.022
response to nitrogen compoundGO:19016981840.022
somatic recombination of immunoglobulin gene segmentsGO:001644740.022
regulation of leukocyte activationGO:00026941150.022
establishment of protein localization to organelleGO:00725941720.022
regulation of transferase activityGO:00513383550.022
maintenance of locationGO:00512351120.022
cell growthGO:00160491600.022
negative regulation of hydrolase activityGO:00513461820.022
regulation of cell motilityGO:20001452990.022
negative regulation of protein metabolic processGO:00512483910.021
regulation of cellular ketone metabolic processGO:0010565500.021
negative regulation of proteolysisGO:00458611320.021
dna geometric changeGO:0032392320.021
dephosphorylationGO:00163112090.021
central nervous system developmentGO:00074171230.021
regulation of peptidase activityGO:00525471800.021
positive regulation of cell deathGO:00109422630.021
oocyte developmentGO:004859910.021
positive regulation of transcription from rna polymerase ii promoter during mitosisGO:004602210.021
posttranscriptional regulation of gene expressionGO:00106082130.021
regulation of reactive oxygen species biosynthetic processGO:190342630.020
regulation of protein ubiquitinationGO:0031396950.020
negative regulation of cell cycleGO:00457861930.020
Human
neurogenesisGO:00220081690.020
regulation of secretionGO:00510461940.020
positive regulation of cellular catabolic processGO:00313312840.020
negative regulation of cell cycle processGO:00109481210.020
Human
negative regulation of cellular protein metabolic processGO:00322693530.020
positive regulation of protein phosphorylationGO:00019343130.020
reactive oxygen species metabolic processGO:0072593750.020
protein localization to membraneGO:00726571600.020
amine metabolic processGO:0009308440.020
negative regulation of intracellular signal transductionGO:19025321830.020
histone h3 k4 methylationGO:0051568270.020
response to radiationGO:00093141510.019
negative regulation of protein modification processGO:00314002000.019
regulation of growthGO:00400081650.019
negative regulation of cell proliferationGO:00082852280.019
regulation of cellular component biogenesisGO:00440872810.019
nuclear divisionGO:00002801280.019
phosphatidylinositol 3 phosphate biosynthetic processGO:003609230.019
secretion by cellGO:00329402260.019
response to organonitrogen compoundGO:00102431560.019
positive regulation of nucleotide metabolic processGO:00459812300.019
somitogenesisGO:000175620.018
dna damage response signal transduction by p53 class mediatorGO:0030330440.018
neurological system processGO:00508771630.018
blastocyst developmentGO:000182430.018
oocyte differentiationGO:000999420.018
nitrogen compound transportGO:00717051910.018
cellular amine metabolic processGO:0044106410.018
positive regulation of kinase activityGO:00336742040.018
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.018
negative regulation of proteasomal protein catabolic processGO:1901799320.018
negative regulation of phosphorus metabolic processGO:00105632670.018
response to woundingGO:00096111680.018
organophosphate catabolic processGO:00464344300.018
regulation of double strand break repairGO:2000779220.018
intracellular mrna localizationGO:000829810.018
regulation of cellular component movementGO:00512703340.018
defense response to other organismGO:00985421290.017
multicellular organismal agingGO:001025930.017
negative regulation of transferase activityGO:00513481240.017
post embryonic developmentGO:000979120.017
nerve developmentGO:002167540.017
response to other organismGO:00517072610.017
regulation of meiotic cell cycleGO:005144540.017
response to oxidative stressGO:00069791210.017
regulation of peptide transportGO:0090087620.016
female gamete generationGO:000729220.016
wound healingGO:00420601150.016
rho protein signal transductionGO:0007266260.016
regulation of immunoglobulin productionGO:000263740.016
response to metal ionGO:0010038840.016
isotype switchingGO:004519030.016
regulation of purine nucleotide metabolic processGO:19005422640.016
regulation of cell cycle phase transitionGO:19019871260.016
Human
organic hydroxy compound metabolic processGO:19016151470.016
cell activationGO:00017752130.016
fatty acid derivative metabolic processGO:1901568350.016
embryo developmentGO:00097901230.016
lipid localizationGO:00108761060.016
positive regulation of protein complex assemblyGO:0031334860.016
cellular macromolecular complex assemblyGO:00346223240.016
response to hormoneGO:00097251750.016
protein processingGO:00164852260.015
cellular ketone metabolic processGO:0042180800.015
modification dependent protein catabolic processGO:00199412090.015
detection of stimulusGO:0051606850.015
methylation dependent chromatin silencingGO:000634630.015
regulation of cysteine type endopeptidase activityGO:20001161270.015
cell part morphogenesisGO:00329901370.015
hematopoietic stem cell differentiationGO:006021840.015
negative regulation of cellular amino acid metabolic processGO:004576320.015
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.015
endomembrane system organizationGO:00102561960.015
protein modification by small protein removalGO:0070646920.015
protein dephosphorylationGO:0006470810.015
nuclear transportGO:00511691790.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002460400.015
pharyngeal system developmentGO:006003720.015
vesicle mediated transportGO:00161923710.015
negative regulation of cellular protein catabolic processGO:1903363380.015
regulation of reactive oxygen species metabolic processGO:2000377410.015
response to external biotic stimulusGO:00432072610.015
spindle checkpointGO:0031577260.015
positive regulation of apoptotic processGO:00430652460.015
anatomical structure formation involved in morphogenesisGO:00486462840.014
gtp catabolic processGO:00061842370.014
zymogen activationGO:0031638700.014
positive regulation of hydrolase activityGO:00513453310.014
enzyme linked receptor protein signaling pathwayGO:00071673030.014
dna damage response detection of dna damageGO:004276930.014
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.014
response to oxygen containing compoundGO:19017003690.014
regulation of neuroblast proliferationGO:190269230.014
positive regulation of cysteine type endopeptidase activityGO:2001056790.014
protein homooligomerizationGO:00512601000.013
regulation of cell developmentGO:00602841610.013
cellular response to organonitrogen compoundGO:00714171240.013
blastoderm segmentationGO:000735020.013
positive regulation of protein transportGO:00512221350.013
circadian behaviorGO:004851220.013
positive regulation of growthGO:0045927580.013
positive regulation of secretionGO:00510471160.013
segmentationGO:003528240.013
negative regulation of phosphorylationGO:00423261740.013
positive regulation of cellular component movementGO:00512721810.013
positive regulation of mitotic cell cycleGO:0045931600.013
regulation of icosanoid secretionGO:003230340.013
negative regulation of cellular component organizationGO:00511292350.013
regulation of nucleocytoplasmic transportGO:0046822980.013
regulation of stress activated protein kinase signaling cascadeGO:0070302850.013
regulation of hormone levelsGO:00108171250.013
regulation of synaptic plasticityGO:004816730.013
cellular response to oxygen containing compoundGO:19017012760.013
cellular component morphogenesisGO:00329893140.013
signal transduction by phosphorylationGO:00230142970.013
oxidation reduction processGO:00551143960.013
regulation of intracellular protein transportGO:00331571230.013
response to cytokineGO:00340972320.013
developmental growthGO:0048589480.013
response to fungusGO:000962040.013
chromosome segregationGO:00070591140.013
nucleic acid phosphodiester bond hydrolysisGO:00903051020.013
lymphocyte activationGO:00466491330.013
negative regulation of protein catabolic processGO:0042177590.013
embryonic digestive tract developmentGO:0048566100.013
positive regulation of intracellular transportGO:00323881040.013
microtubule based processGO:00070172100.013
protein importGO:00170381300.012
photoreceptor cell differentiationGO:004653020.012
cofactor metabolic processGO:0051186870.012
matingGO:000761810.012
mrna metabolic processGO:00160711750.012
positive regulation of endopeptidase activityGO:0010950840.012
positive regulation of cytokine productionGO:00018191670.012
positive regulation of nervous system developmentGO:0051962540.012
organic acid biosynthetic processGO:0016053970.012
activation of immune responseGO:00022531140.012
production of molecular mediator of immune responseGO:0002440370.012
establishment of organelle localizationGO:0051656590.012
cellular response to tumor necrosis factorGO:0071356630.012
regulation of nucleotide metabolic processGO:00061402690.012
regulation of secretion by cellGO:19035301770.012
nucleosome organizationGO:0034728660.012
regulation of protein kinase activityGO:00458592890.012
regulation of endopeptidase activityGO:00525481700.012
cilium organizationGO:0044782680.012
compound eye developmentGO:004874910.012
cell cycle phase transitionGO:00447701730.012
Human
limbic system developmentGO:002176130.012
regulation of apoptotic signaling pathwayGO:20012331750.012
cytokine productionGO:00018162470.012
anion transportGO:00068201610.011
innate immune responseGO:00450871780.011
determination of adult lifespanGO:000834020.011
inner ear morphogenesisGO:004247240.011
positive regulation of reactive oxygen species metabolic processGO:2000379240.011
single organism membrane organizationGO:00448022680.011
monocarboxylic acid metabolic processGO:00327871850.011
regulation of mitotic cell cycle phase transitionGO:19019901180.011
Human
unsaturated fatty acid metabolic processGO:0033559370.011
regulation of cellular protein catabolic processGO:1903362960.011
cell activation involved in immune responseGO:0002263300.011
regulation of dephosphorylationGO:0035303960.011
regulation of purine nucleotide catabolic processGO:00331212050.011
apoptotic signaling pathwayGO:00971902680.011
positive regulation of purine nucleotide catabolic processGO:00331231850.011
positive regulation of nucleotide catabolic processGO:00308131850.011
immune response regulating signaling pathwayGO:0002764970.011
positive regulation of purine nucleotide metabolic processGO:19005442270.011
immune response activating signal transductionGO:0002757900.011
spermatid differentiationGO:004851540.011
phospholipid metabolic processGO:0006644990.011
peripheral nervous system developmentGO:000742220.011
regulation of cell migrationGO:00303342890.011
regulation of cellular amino acid metabolic processGO:000652160.011
regulation of transcription involved in cell fate commitmentGO:006085060.011
negative regulation of organelle organizationGO:00106391260.011
single organism nuclear importGO:19025931040.011
lymphocyte proliferationGO:0046651700.011
positive regulation of immune responseGO:00507781590.011
organonitrogen compound biosynthetic processGO:19015662000.011
regulation of dna metabolic processGO:00510521530.011
dna duplex unwindingGO:0032508300.011
protein autophosphorylationGO:00467771230.010
positive regulation of immunoglobulin mediated immune responseGO:000289140.010
purine ribonucleoside metabolic processGO:00461284370.010
transmembrane transportGO:00550853990.010
startle responseGO:000196430.010
cell projection morphogenesisGO:00488581290.010
positive regulation of cell proliferationGO:00082843010.010
sequestering of metal ionGO:0051238240.010
regulation of cytokine productionGO:00018172320.010
dna damage checkpointGO:0000077680.010
sequestering of calcium ionGO:0051208170.010
carboxylic acid biosynthetic processGO:0046394970.010
spermatid developmentGO:000728640.010
regulation of bindingGO:00510981110.010
neuroblast proliferationGO:000740540.010
myeloid cell differentiationGO:00300991170.010
signal transduction by p53 class mediatorGO:0072331720.010
regulation of transcription from rna polymerase ii promoter mitoticGO:004602110.010
negative regulation of cellular catabolic processGO:0031330830.010
sensory perception of painGO:001923340.010
signal transduction involved in mitotic dna integrity checkpointGO:1902403130.010
epithelium developmentGO:00604292270.010
negative regulation of protein phosphorylationGO:00019331400.010
regulation of protein stabilityGO:0031647870.010
memoryGO:000761330.010
regulation of protein localization to nucleusGO:1900180850.010

RNF8 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:29141550.057
disease of mental healthDOID:150700.023
disease of cellular proliferationDOID:145661740.021
cancerDOID:1621670.021
nervous system diseaseDOID:8634310.018
central nervous system diseaseDOID:3311860.018
aplastic anemiaDOID:12449300.018
anemiaDOID:2355550.018
bone marrow diseaseDOID:4961310.018
hematopoietic system diseaseDOID:741000.018
muscle tissue diseaseDOID:661130.017
muscular diseaseDOID:00800001140.017
musculoskeletal system diseaseDOID:172230.017
myopathyDOID:4231040.017
organ system cancerDOID:00506861640.015
sensory system diseaseDOID:00501552030.013
eye diseaseDOID:56141490.013
eye and adnexa diseaseDOID:14921500.013
neurodegenerative diseaseDOID:12891020.013