Homo sapiens

54 known processes

NHEJ1

nonhomologous end-joining factor 1

(Aliases: XLF,FLJ12610)

NHEJ1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
immunoglobulin v d j recombinationGO:003315210.330
pro b cell differentiationGO:000232810.205
dna ligation involved in dna repairGO:005110340.199
immune responseGO:00069553070.078
post embryonic developmentGO:000979120.071
cellular amino acid metabolic processGO:00065201160.065
somatic stem cell maintenanceGO:003501940.063
dephosphorylationGO:00163112090.062
cellular response to dna damage stimulusGO:00069743790.059
dna ligationGO:0006266100.058
t cell differentiation in thymusGO:003307740.057
response to radiationGO:00093141510.055
regulation of cell differentiationGO:00455953930.053
somatic diversification of immunoglobulins involved in immune responseGO:000220830.051
positive regulation of cell proliferationGO:00082843010.050
positive regulation of cell differentiationGO:00455972110.050
hematopoietic or lymphoid organ developmentGO:00485341860.047
negative regulation of apoptotic processGO:00430663160.046
immune effector processGO:00022521590.045
cell activationGO:00017752130.045
negative regulation of programmed cell deathGO:00430693210.044
negative regulation of cell deathGO:00605483450.044
leukocyte activationGO:00453211640.044
amine metabolic processGO:0009308440.041
cellular amine metabolic processGO:0044106410.041
response to abiotic stimulusGO:00096283360.041
somatic recombination of immunoglobulin gene segmentsGO:001644740.040
regulation of cellular amine metabolic processGO:0033238110.039
cell developmentGO:00484683280.039
regulation of cellular amino acid metabolic processGO:000652160.038
dna repairGO:00062811980.037
isotype switchingGO:004519030.037
response to oxygen containing compoundGO:19017003690.037
t cell activationGO:0042110990.035
cellular ketone metabolic processGO:0042180800.035
regulation of cellular ketone metabolic processGO:0010565500.034
positive regulation of developmental processGO:00510943140.034
lipid metabolic processGO:00066293810.032
female gamete generationGO:000729220.032
determination of adult lifespanGO:000834020.031
lymphocyte activationGO:00466491330.031
regulation of cell developmentGO:00602841610.030
cellular lipid metabolic processGO:00442553030.030
locomotory behaviorGO:000762610.030
positive regulation of cellular amino acid metabolic processGO:004576430.029
nervous system developmentGO:00073992930.029
oxidation reduction processGO:00551143960.029
negative regulation of protein metabolic processGO:00512483910.029
positive regulation of cellular amine metabolic processGO:003324070.028
fibroblast proliferationGO:0048144330.028
multicellular organismal agingGO:001025930.027
organophosphate catabolic processGO:00464344300.026
transmembrane transportGO:00550853990.026
purine ribonucleoside metabolic processGO:00461284370.025
single organism cellular localizationGO:19025803320.025
cellular macromolecule catabolic processGO:00442653800.025
negative regulation of catalytic activityGO:00430863350.025
immune system developmentGO:00025201950.025
v d j recombinationGO:003315130.025
cytoplasmic transportGO:00164823790.025
positive regulation of cell developmentGO:0010720920.024
negative regulation of cell differentiationGO:00455961710.024
positive regulation of hydrolase activityGO:00513453310.024
purine nucleotide catabolic processGO:00061954050.024
purine ribonucleoside triphosphate catabolic processGO:00092073910.024
negative regulation of cellular protein metabolic processGO:00322693530.023
dna recombinationGO:0006310770.023
cell type specific apoptotic processGO:00972851250.023
positive regulation of cellular component organizationGO:00511303760.023
single organism membrane organizationGO:00448022680.023
adaptive immune responseGO:0002250490.023
glycosyl compound catabolic processGO:19016584130.023
segmentationGO:003528240.023
organonitrogen compound biosynthetic processGO:19015662000.022
oogenesisGO:004847720.022
protein catabolic processGO:00301633250.022
negative regulation of phosphate metabolic processGO:00459362670.022
protein maturationGO:00516042330.022
positive regulation of catabolic processGO:00098963100.022
generation of neuronsGO:00486991520.022
system processGO:00030083490.022
leukocyte mediated immunityGO:0002443590.022
nucleoside triphosphate metabolic processGO:00091414220.022
negative regulation of phosphorus metabolic processGO:00105632670.022
cation transportGO:00068123310.021
hematopoietic progenitor cell differentiationGO:0002244380.021
chromatin organizationGO:00063253510.021
neuromuscular junction developmentGO:000752830.021
positive regulation of phosphorylationGO:00423273940.021
response to ionizing radiationGO:0010212650.021
lymphoid progenitor cell differentiationGO:000232030.021
defense responseGO:00069523150.021
somatic recombination of immunoglobulin genes involved in immune responseGO:000220430.021
regulation of proteolysisGO:00301622930.021
posttranscriptional regulation of gene expressionGO:00106082130.021
purine containing compound catabolic processGO:00725234110.021
ras protein signal transductionGO:0007265730.021
regulation of cell cycleGO:00517263930.021
nucleotide catabolic processGO:00091664080.021
lymphocyte mediated immunityGO:0002449480.020
replicative cell agingGO:000130230.020
purine ribonucleotide catabolic processGO:00091544040.020
ribonucleotide catabolic processGO:00092614050.020
protein localization to organelleGO:00333652800.020
ion transmembrane transportGO:00342203380.020
purine ribonucleoside catabolic processGO:00461303980.020
memoryGO:000761330.020
nucleoside catabolic processGO:00091644080.020
nucleoside triphosphate catabolic processGO:00091433940.020
regenerationGO:003109940.020
regulation of nucleotide metabolic processGO:00061402690.020
regulation of transferase activityGO:00513383550.020
membrane organizationGO:00610242920.020
purine nucleoside triphosphate catabolic processGO:00091463920.019
rna processingGO:00063962550.019
regulation of ligase activityGO:0051340290.019
cellular protein catabolic processGO:00442572610.019
actin filament based processGO:00300292240.019
ribonucleoside catabolic processGO:00424544060.019
lipid biosynthetic processGO:00086101770.019
protein processingGO:00164852260.019
biological adhesionGO:00226103310.019
positive regulation of transportGO:00510503360.019
chemical homeostasisGO:00488783060.019
rho protein signal transductionGO:0007266260.019
mitotic cell cycleGO:00002783260.019
nucleic acid phosphodiester bond hydrolysisGO:00903051020.019
regulation of kinase activityGO:00435493140.019
vesicle mediated transportGO:00161923710.019
purine nucleoside triphosphate metabolic processGO:00091444120.019
positive regulation of cellular catabolic processGO:00313312840.019
rhythmic behaviorGO:000762220.019
single organism carbohydrate metabolic processGO:00447231930.019
response to external biotic stimulusGO:00432072610.019
ribonucleoside triphosphate metabolic processGO:00091994120.019
negative regulation of cellular amine metabolic processGO:003323930.019
positive regulation of synaptic transmissionGO:005080640.019
blastoderm segmentationGO:000735020.018
positive regulation of immune system processGO:00026842830.018
cation transmembrane transportGO:00986552380.018
negative regulation of cellular amino acid metabolic processGO:004576320.018
mitochondrion organizationGO:00070051560.018
apoptotic signaling pathwayGO:00971902680.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002460400.018
regulation of purine nucleotide metabolic processGO:19005422640.018
positive regulation of neurogenesisGO:0050769490.018
purine ribonucleoside triphosphate metabolic processGO:00092054110.018
regulation of protein localizationGO:00328802960.018
small gtpase mediated signal transductionGO:0007264780.018
cardiac muscle cell contractionGO:008600340.018
regulation of establishment of protein localizationGO:00702012420.018
nucleotide excision repairGO:0006289310.018
carbohydrate metabolic processGO:00059752070.018
purine nucleoside catabolic processGO:00061523980.018
positive regulation of cell deathGO:00109422630.017
ribonucleoside triphosphate catabolic processGO:00092033910.017
inorganic ion transmembrane transportGO:00986602310.017
positive regulation of nucleotide metabolic processGO:00459812300.017
anterior posterior axis specificationGO:000994820.017
adult locomotory behaviorGO:000834410.017
metal ion transportGO:00300012720.017
regulation of cell cycle processGO:00105642660.017
release of cytoplasmic sequestered nf kappabGO:000858840.017
mitotic cell cycle processGO:19030472860.017
histone modificationGO:00165702510.017
nucleoside phosphate catabolic processGO:19012924120.017
negative regulation of cellular component organizationGO:00511292350.017
positive regulation of purine nucleotide metabolic processGO:19005442270.017
negative regulation of multicellular organismal processGO:00512413170.017
circadian behaviorGO:004851220.017
regulation of protein transportGO:00512232130.017
regulation of cellular component movementGO:00512703340.017
compound eye developmentGO:004874910.017
reactive oxygen species biosynthetic processGO:190340940.017
regulation of protein kinase activityGO:00458592890.017
organophosphate biosynthetic processGO:00904071630.017
positive regulation of programmed cell deathGO:00430682490.017
morphogenesis of embryonic epitheliumGO:001633140.017
cellular macromolecular complex assemblyGO:00346223240.016
cell adhesionGO:00071553250.016
regulation of cellular response to stressGO:00801352440.016
negative regulation of protein modification processGO:00314002000.016
monocarboxylic acid metabolic processGO:00327871850.016
negative regulation of developmental processGO:00510932470.016
gtp catabolic processGO:00061842370.016
guanosine containing compound catabolic processGO:19010692390.016
proteolysis involved in cellular protein catabolic processGO:00516032440.016
signal transduction by phosphorylationGO:00230142970.016
chromatin modificationGO:00165682980.016
innate immune responseGO:00450871780.016
covalent chromatin modificationGO:00165692540.016
reactive nitrogen species metabolic processGO:200105730.016
regulation of cytokine productionGO:00018172320.016
regulation of purine nucleotide catabolic processGO:00331212050.016
nitrogen compound transportGO:00717051910.016
double strand break repairGO:00063021010.016
regulation of gtp catabolic processGO:00331241800.016
detection of stimulusGO:0051606850.016
inorganic cation transmembrane transportGO:00986621940.016
regulation of nucleotide catabolic processGO:00308112050.016
neurogenesisGO:00220081690.016
regulation of response to external stimulusGO:00321012220.016
leukocyte differentiationGO:0002521980.016
sex determinationGO:000753030.015
secretionGO:00469032540.015
anterior posterior axis specification embryoGO:000859520.015
positive regulation of apoptotic processGO:00430652460.015
maintenance of locationGO:00512351120.015
gtp metabolic processGO:00460392390.015
regulation of anatomical structure morphogenesisGO:00226032860.015
cellular response to oxygen containing compoundGO:19017012760.015
negative regulation of hydrolase activityGO:00513461820.015
intracellular protein transportGO:00068862700.015
guanosine containing compound metabolic processGO:19010682440.015
regulation of synaptic plasticityGO:004816730.015
organ formationGO:004864530.015
b cell activationGO:0042113330.015
neurotransmitter secretionGO:000726940.015
proteasomal protein catabolic processGO:00104981760.015
regulation of intracellular transportGO:00323861950.015
cell morphogenesisGO:00009022960.015
response to other organismGO:00517072610.015
negative regulation of intracellular signal transductionGO:19025321830.015
regulation of nervous system developmentGO:0051960880.015
central nervous system developmentGO:00074171230.015
cytokine productionGO:00018162470.015
oocyte developmentGO:004859910.015
matingGO:000761810.015
regulation of fibroblast proliferationGO:0048145320.015
associative learningGO:000830610.015
cellular response to endogenous stimulusGO:00714953360.015
actin filament based movementGO:0030048170.015
motor neuron axon guidanceGO:000804520.015
ion homeostasisGO:00508012300.015
positive regulation of organelle organizationGO:00106381950.014
actin mediated cell contractionGO:0070252120.014
positive regulation of fibroblast proliferationGO:0048146210.014
response to biotic stimulusGO:00096072760.014
regulation of protein catabolic processGO:00421761550.014
negative regulation of transportGO:00510511760.014
carbohydrate derivative biosynthetic processGO:19011372070.014
regulation of gtpase activityGO:00430871800.014
regulation of locomotionGO:00400123290.014
tripartite regional subdivisionGO:000735120.014
cellular component morphogenesisGO:00329893140.014
stem cell differentiationGO:0048863930.014
peptidyl lysine modificationGO:00182051440.014
reactive oxygen species metabolic processGO:0072593750.014
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.014
small molecule biosynthetic processGO:00442831570.014
nuclear transportGO:00511691790.014
positive regulation of ligase activityGO:0051351190.014
positive regulation of protein phosphorylationGO:00019343130.014
hindbrain developmentGO:003090230.014
cellular protein complex assemblyGO:00436231880.014
regulation of cell motilityGO:20001452990.014
neurological system processGO:00508771630.014
secretion by cellGO:00329402260.014
internal peptidyl lysine acetylationGO:0018393970.014
oocyte differentiationGO:000999420.014
anion transportGO:00068201610.014
spermatid differentiationGO:004851540.014
regulation of secretionGO:00510461940.014
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.014
protein oligomerizationGO:00512591730.014
startle responseGO:000196430.014
peripheral nervous system developmentGO:000742220.014
embryonic epithelial tube formationGO:000183840.014
neuron deathGO:0070997650.013
positive regulation of kinase activityGO:00336742040.013
positive regulation of gtp catabolic processGO:00331261660.013
response to lipidGO:00339932060.013
regulation of protein stabilityGO:0031647870.013
regulation of reactive oxygen species biosynthetic processGO:190342630.013
regulation of nucleoside metabolic processGO:00091182090.013
regulation of immune responseGO:00507762010.013
protein acylationGO:00435431380.013
ubiquitin dependent protein catabolic processGO:00065112060.013
response to gamma radiationGO:0010332140.013
sequestering of metal ionGO:0051238240.013
dna damage response detection of dna damageGO:004276930.013
cell activation involved in immune responseGO:0002263300.013
multi organism cellular processGO:00447641560.013
small molecule catabolic processGO:0044282920.013
inner ear morphogenesisGO:004247240.013
carboxylic acid biosynthetic processGO:0046394970.013
protein modification by small protein conjugationGO:00324463420.013
cofactor metabolic processGO:0051186870.013
detection of muramyl dipeptideGO:003249810.013
positive regulation of transferase activityGO:00513472270.013
negative regulation of phosphorylationGO:00423261740.013
cell projection organizationGO:00300302520.013
positive regulation of nucleotide catabolic processGO:00308131850.013
regulation of peptidase activityGO:00525471800.013
protein ubiquitinationGO:00165673140.013
protein localization to membraneGO:00726571600.013
production of molecular mediator of immune responseGO:0002440370.013
cell cycle phase transitionGO:00447701730.013
visual behaviorGO:000763220.013
cell agingGO:0007569520.013
hemopoiesisGO:00300971800.013
mapk cascadeGO:00001652880.013
response to axon injuryGO:004867810.013
modification dependent macromolecule catabolic processGO:00436322120.013
sensory perception of painGO:001923340.013
cation homeostasisGO:00550801890.013
positive regulation of gtpase activityGO:00435471660.013
regulation of neuron deathGO:1901214560.013
positive regulation of purine nucleotide catabolic processGO:00331231850.013
response to fungusGO:000962040.013
positive regulation of nucleoside metabolic processGO:00459791860.013
leukocyte activation involved in immune responseGO:0002366300.013
cellular homeostasisGO:00197251960.013
intracellular mrna localizationGO:000829810.013
regulation of protein processingGO:00706131500.013
organic acid biosynthetic processGO:0016053970.013
regulation of ras protein signal transductionGO:00465781550.013
modification dependent protein catabolic processGO:00199412090.013
mitotic cell cycle phase transitionGO:00447721620.013
lens development in camera type eyeGO:000208820.013
specification of organ identityGO:001009230.013
divalent inorganic cation transportGO:00725111580.013
long term memoryGO:000761620.012
purine ribonucleoside monophosphate metabolic processGO:00091671860.012
nucleoside monophosphate metabolic processGO:00091231910.012
photoreceptor cell differentiationGO:004653020.012
sequestering of calcium ionGO:0051208170.012
response to oxidative stressGO:00069791210.012
cell divisionGO:00513011680.012
protein targetingGO:00066051870.012
peptidyl lysine acetylationGO:00183941010.012
negative regulation of cell proliferationGO:00082852280.012
metencephalon developmentGO:002203720.012
spermatid developmentGO:000728640.012
nerve developmentGO:002167540.012
morphogenesis of a polarized epitheliumGO:000173830.012
divalent metal ion transportGO:00708381520.012
regulation of neural precursor cell proliferationGO:200017740.012
neuroblast proliferationGO:000740540.012
salivary gland morphogenesisGO:000743540.012
rna interferenceGO:001624640.012
negative regulation of organelle organizationGO:00106391260.012
positive regulation of cytokine productionGO:00018191670.012
regulation of endopeptidase activityGO:00525481700.012
regulation of cell migrationGO:00303342890.012
regulation of multi organism processGO:00439001570.012
syncytium formation by plasma membrane fusionGO:000076820.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
interspecies interaction between organismsGO:00444191560.012
negative regulation of protein processingGO:00109551420.012
internal protein amino acid acetylationGO:00064751010.012
regulation of protein maturationGO:19033171500.012
cell growthGO:00160491600.012
regulation of small gtpase mediated signal transductionGO:00510561560.012
lymphocyte differentiationGO:0030098350.012
coenzyme metabolic processGO:0006732650.012
spinal cord developmentGO:002151040.012
regulation of ion transportGO:00432691890.012
response to inorganic substanceGO:00100351270.012
response to cytokineGO:00340972320.012
calcium ion transportGO:00068161470.012
symbiosis encompassing mutualism through parasitismGO:00444031560.012
tissue regenerationGO:004224630.012
protein acetylationGO:00064731160.012
regulation of secretion by cellGO:19035301770.012
regulation of neuron apoptotic processGO:0043523350.012
cellular cation homeostasisGO:00300031630.012
pituitary gland developmentGO:002198320.012
myoblast fusionGO:000752010.012
regulation of defense responseGO:00313471540.011
negative regulation of proteolysisGO:00458611320.011
negative regulation of cell cycleGO:00457861930.011
wnt signaling pathwayGO:00160551560.011
response to organic cyclic compoundGO:00140702040.011
meiotic chromosome segregationGO:004513240.011
regulation of cellular component biogenesisGO:00440872810.011
enzyme linked receptor protein signaling pathwayGO:00071673030.011
organic hydroxy compound metabolic processGO:19016151470.011
positive regulation of transcription from rna polymerase ii promoter during mitosisGO:004602210.011
neuron apoptotic processGO:0051402390.011
viral life cycleGO:00190581320.011
epidermis morphogenesisGO:004873030.011
regulation of sequence specific dna binding transcription factor activityGO:00510902110.011
regulation of mapk cascadeGO:00434082620.011
sulfur compound metabolic processGO:00067901010.011
stem cell divisionGO:001714520.011
regulation of cytoplasmic transportGO:19036491490.011
establishment of planar polarityGO:000173630.011
organelle fissionGO:00482851490.011
sensory perception of smellGO:000760820.011
regulation of cell growthGO:00015581350.011
endomembrane system organizationGO:00102561960.011
nucleocytoplasmic transportGO:00069131760.011
protein homooligomerizationGO:00512601000.011
negative regulation of protein maturationGO:19033181420.011
positive regulation of proteolysisGO:00458621420.011
regulation of cell adhesionGO:00301551660.011
regulation of apoptotic signaling pathwayGO:20012331750.011
single organism cell adhesionGO:00986021790.011
visual learningGO:000854210.011
single strand break repairGO:000001260.011
regulation of i kappab kinase nf kappab signalingGO:00431221620.011
histone acetylationGO:0016573930.011
negative regulation of protein phosphorylationGO:00019331400.011
regulation of meiotic cell cycleGO:005144540.011
response to hormoneGO:00097251750.011
positive regulation of cell cycleGO:00457871400.011
regulation of cysteine type endopeptidase activityGO:20001161270.011
negative regulation of transferase activityGO:00513481240.011
actin cytoskeleton organizationGO:00300362070.011
regulation of cell divisionGO:00513021160.011
protein dephosphorylationGO:0006470810.011
t cell differentiationGO:0030217290.011
positive regulation of ras gtpase activityGO:00323201170.011
rab protein signal transductionGO:003248240.011
response to organonitrogen compoundGO:00102431560.011
alcohol metabolic processGO:00060661140.011
regulation of reactive oxygen species metabolic processGO:2000377410.011
organelle assemblyGO:00709251760.011
somatic muscle developmentGO:000752510.011
positive regulation of transcription during mitosisGO:004589720.011
histone h3 acetylationGO:0043966450.011
positive regulation of protein kinase activityGO:00458601900.011
negative regulation of synaptic transmissionGO:005080520.011
regulation of mitotic cell cycleGO:00073461890.011
response to woundingGO:00096111680.011
positive regulation of secretionGO:00510471160.011
regulation of ras gtpase activityGO:00323181280.011
mitotic nuclear divisionGO:00070671190.011
positive regulation of nervous system developmentGO:0051962540.011
forelimb morphogenesisGO:003513640.011
heart formationGO:006091420.011
microtubule based processGO:00070172100.011
establishment or maintenance of bipolar cell polarityGO:006124520.011
cerebellum developmentGO:002154920.010
cellular chemical homeostasisGO:00550821800.010
sleepGO:003043120.010
behavioral response to ethanolGO:004814920.010
positive regulation of mapk cascadeGO:00434101900.010
establishment or maintenance of apical basal cell polarityGO:003508820.010
i kappab kinase nf kappab signalingGO:00072491660.010
cellular metal ion homeostasisGO:00068751460.010
regulation of transcription during mitosisGO:004589620.010
cell fate determinationGO:000170930.010
positive regulation of cellular component movementGO:00512721810.010
cell projection assemblyGO:00300311260.010
negative regulation of blood pressureGO:004577630.010
cellular response to cytokine stimulusGO:00713451810.010
neural tube formationGO:000184130.010
regulation of neurotransmitter secretionGO:004692830.010
establishment of tissue polarityGO:000716430.010
anatomical structure formation involved in morphogenesisGO:00486462840.010
defense response to fungusGO:005083240.010
cell part morphogenesisGO:00329901370.010
post embryonic organ developmentGO:004856910.010
axon cargo transportGO:000808820.010
primary neural tube formationGO:001402030.010
methylationGO:00322591060.010
embryo developmentGO:00097901230.010
somitogenesisGO:000175620.010
negative regulation of neuron apoptotic processGO:0043524230.010
metal ion homeostasisGO:00550651690.010

NHEJ1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:29141550.066
disease of cellular proliferationDOID:145661740.061
cancerDOID:1621670.043
organ system cancerDOID:00506861640.043
central nervous system diseaseDOID:3311860.043
nervous system diseaseDOID:8634310.043
neonatal period electroclinical syndromeDOID:0050702190.040
epilepsy syndromeDOID:1826410.040
electroclinical syndromeDOID:0050701320.040
brain diseaseDOID:936730.040
disease of metabolismDOID:00146672950.038
inherited metabolic disorderDOID:6552420.031
musculoskeletal system diseaseDOID:172230.021
primary immunodeficiency diseaseDOID:612360.021
sensory system diseaseDOID:00501552030.020
eye and adnexa diseaseDOID:14921500.019
eye diseaseDOID:56141490.019
neurodegenerative diseaseDOID:12891020.016
retinal diseaseDOID:56791180.015
muscular diseaseDOID:00800001140.015
muscle tissue diseaseDOID:661130.015
amino acid metabolic disorderDOID:9252500.015
connective tissue diseaseDOID:651090.014
cardiovascular system diseaseDOID:12871060.014
bone diseaseDOID:0080001880.014
hematopoietic system diseaseDOID:741000.014
myopathyDOID:4231040.014
idiopathic generalized epilepsyDOID:1827210.012
disease of mental healthDOID:150700.012
retinal degenerationDOID:8466890.011
heart diseaseDOID:114680.011