Homo sapiens

17 known processes

COPS4

COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)

(Aliases: CSN4,MGC10899,MGC15160)

COPS4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein deneddylationGO:0000338101.000
cullin deneddylationGO:001038890.997
protein modification by small protein removalGO:0070646920.993
positive regulation of synaptic vesicle transportGO:190280510.970
cytokinesisGO:0000910960.885
Worm
regulation of catecholamine uptake involved in synaptic transmissionGO:005194040.841
g2 dna damage checkpointGO:0031572260.832
Fly
regulation of synaptic transmission dopaminergicGO:003222540.824
regulation of synaptic vesicle endocytosisGO:190024210.812
regulation of synaptic vesicle recyclingGO:190342110.765
regulation of neurotransmitter uptakeGO:005158040.761
mitotic cell cycle phase transitionGO:00447721620.748
Fly
negative regulation of cell cycle phase transitionGO:1901988890.744
Fly
regulation of dopamine uptake involved in synaptic transmissionGO:005158440.722
endoplasmic reticulum organizationGO:0007029200.713
positive regulation of synaptic vesicle recyclingGO:190342310.711
cyclin catabolic processGO:000805460.700
mitotic cell cycle checkpointGO:0007093680.688
Fly
positive regulation of synaptic vesicle endocytosisGO:190024410.682
negative regulation of cell cycle processGO:00109481210.681
Fly
regulation of cell cycle processGO:00105642660.669
Fly
regulation of cell cycleGO:00517263930.595
Fly
mitotic dna damage checkpointGO:0044773280.551
Fly
dopamine uptakeGO:009049440.540
mitotic cell cycleGO:00002783260.539
Fly
regulation of mitotic cell cycleGO:00073461890.531
Fly
cell cycle checkpointGO:00000751170.529
Fly
ubiquitin dependent protein catabolic processGO:00065112060.510
Fly
negative regulation of mitotic cell cycle phase transitionGO:1901991850.489
Fly
regulation of mitotic cell cycle phase transitionGO:19019901180.478
Fly
proteolysis involved in cellular protein catabolic processGO:00516032440.465
Fly
nucleoside monophosphate metabolic processGO:00091231910.455
cellular protein catabolic processGO:00442572610.411
Fly
purine ribonucleoside monophosphate catabolic processGO:00091691580.387
atp catabolic processGO:00062001570.378
mitotic cell cycle processGO:19030472860.364
Fly
single organism cellular localizationGO:19025803320.315
dopamine transportGO:001587250.312
protein modification by small protein conjugationGO:00324463420.306
mitotic dna integrity checkpointGO:0044774300.304
Fly
cellular response to dna damage stimulusGO:00069743790.288
Fly
glial cell migrationGO:000834740.284
cell divisionGO:00513011680.273
Worm
negative regulation of cell cycleGO:00457861930.271
Fly
cell cycle phase transitionGO:00447701730.270
Fly
purine ribonucleoside monophosphate metabolic processGO:00091671860.268
cell cell signalingGO:00072671550.264
Fly
ribonucleoside monophosphate metabolic processGO:00091611870.258
regulation of kinase activityGO:00435493140.257
post embryonic developmentGO:000979120.254
Worm
positive regulation of catabolic processGO:00098963100.254
ribonucleoside monophosphate catabolic processGO:00091581580.252
nucleoside monophosphate catabolic processGO:00091251590.250
regulation of cell cycle phase transitionGO:19019871260.250
Fly
dna integrity checkpointGO:0031570710.249
Fly
organelle localizationGO:0051640840.248
positive regulation of phosphorylationGO:00423273940.248
dopamine uptake involved in synaptic transmissionGO:005158340.246
positive regulation of protein serine threonine kinase activityGO:00719021190.245
mitotic g2 m transition checkpointGO:004481890.231
Fly
catecholamine transportGO:005193760.228
generation of neuronsGO:00486991520.225
Fly
purine nucleoside monophosphate metabolic processGO:00091261860.209
nervous system developmentGO:00073992930.208
Fly
purine nucleoside monophosphate catabolic processGO:00091281580.203
positive regulation of transportGO:00510503360.200
microtubule based processGO:00070172100.179
regulation of transferase activityGO:00513383550.179
establishment of organelle localizationGO:0051656590.173
negative regulation of cell proliferationGO:00082852280.162
neuron differentiationGO:00301821380.148
Fly
activation of protein kinase activityGO:0032147900.147
negative regulation of mitotic cell cycleGO:00459301020.146
Fly
atp metabolic processGO:00460341760.146
purine nucleoside triphosphate catabolic processGO:00091463920.141
nik nf kappab signalingGO:0038061120.139
regulation of protein localizationGO:00328802960.138
regulation of amine transportGO:005195250.136
cellular macromolecule catabolic processGO:00442653800.135
Fly
protein oligomerizationGO:00512591730.135
purine ribonucleotide catabolic processGO:00091544040.134
positive regulation of synaptic transmissionGO:005080640.133
dna damage checkpointGO:0000077680.132
Fly
positive regulation of protein phosphorylationGO:00019343130.130
ribonucleotide catabolic processGO:00092614050.128
nucleotide catabolic processGO:00091664080.124
positive regulation of cellular component organizationGO:00511303760.124
protein localization to organelleGO:00333652800.119
regulation of mitosisGO:0007088630.116
neuron developmentGO:00486661130.112
protein foldingGO:0006457380.108
anterior posterior axis specification embryoGO:000859520.108
posttranscriptional regulation of gene expressionGO:00106082130.108
Fly
vesicle mediated transportGO:00161923710.107
modification dependent macromolecule catabolic processGO:00436322120.102
Fly
establishment of vesicle localizationGO:0051650230.100
cell projection organizationGO:00300302520.097
nucleoside triphosphate metabolic processGO:00091414220.094
positive regulation of transferase activityGO:00513472270.091
protein polyubiquitinationGO:00002091100.091
protein homooligomerizationGO:00512601000.091
regulation of cellular amine metabolic processGO:0033238110.089
positive regulation of organelle organizationGO:00106381950.088
purine ribonucleoside catabolic processGO:00461303980.088
endocytosisGO:00068971590.085
cellular amine metabolic processGO:0044106410.084
regulation of protein kinase activityGO:00458592890.084
positive regulation of cell cycleGO:00457871400.081
purine ribonucleoside metabolic processGO:00461284370.080
cell cell signaling involved in cell fate commitmentGO:004516850.079
Fly
purine nucleotide catabolic processGO:00061954050.078
protein catabolic processGO:00301633250.078
Fly
neuron projection developmentGO:00311751060.068
modification dependent protein catabolic processGO:00199412090.068
Fly
embryo developmentGO:00097901230.067
Worm
chaperone mediated protein transportGO:007232150.067
blastoderm segmentationGO:000735020.066
protein localization to nucleusGO:00345041360.066
tripartite regional subdivisionGO:000735120.066
positive regulation of kinase activityGO:00336742040.066
nucleoside catabolic processGO:00091644080.065
regulation of protein serine threonine kinase activityGO:00719001790.064
mapk cascadeGO:00001652880.063
positive regulation of protein catabolic processGO:0045732750.062
neurogenesisGO:00220081690.061
Fly
positive regulation of nucleotide catabolic processGO:00308131850.059
purine ribonucleoside triphosphate metabolic processGO:00092054110.059
positive regulation of cellular amine metabolic processGO:003324070.058
regulation of protein transportGO:00512232130.057
positive regulation of cell cycle processGO:00900681060.057
microtubule cytoskeleton organizationGO:00002261760.056
segmentationGO:003528240.055
positive regulation of protein kinase activityGO:00458601900.054
female gamete generationGO:000729220.052
proteasomal protein catabolic processGO:00104981760.049
Fly
catecholamine uptake involved in synaptic transmissionGO:005193440.049
purine ribonucleoside triphosphate catabolic processGO:00092073910.048
positive regulation of cellular catabolic processGO:00313312840.048
regulation of protein stabilityGO:0031647870.047
Fly
multicellular organismal response to stressGO:003355510.046
protein deubiquitinationGO:0016579790.043
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.043
Fly
mitotic cytokinesisGO:0000281190.042
peptidyl lysine modificationGO:00182051440.041
ribonucleoside triphosphate catabolic processGO:00092033910.041
protein ubiquitinationGO:00165673140.041
membrane organizationGO:00610242920.041
positive regulation of protein transportGO:00512221350.039
regulation of protein catabolic processGO:00421761550.039
Fly
purine containing compound catabolic processGO:00725234110.039
positive regulation of meiotic cell cycleGO:005144620.039
catecholamine uptakeGO:009049340.038
positive regulation of cellular amino acid metabolic processGO:004576430.037
internal protein amino acid acetylationGO:00064751010.037
establishment of nucleus localizationGO:004002310.036
nucleoside triphosphate catabolic processGO:00091433940.036
nucleocytoplasmic transportGO:00069131760.036
ribonucleoside triphosphate metabolic processGO:00091994120.036
regulation of metaphase anaphase transition of cell cycleGO:1902099260.036
lipid metabolic processGO:00066293810.035
adult locomotory behaviorGO:000834410.035
chromatin organizationGO:00063253510.035
protein stabilizationGO:0050821640.035
Fly
protein monoubiquitinationGO:0006513390.034
amine metabolic processGO:0009308440.034
neurotransmitter transportGO:0006836100.033
neurotransmitter uptakeGO:000150450.033
regulation of sister chromatid segregationGO:0033045270.032
positive regulation of purine nucleotide metabolic processGO:19005442270.032
purine nucleoside triphosphate metabolic processGO:00091444120.032
synaptic transmission dopaminergicGO:000196350.032
positive regulation of nucleoside metabolic processGO:00459791860.032
regulation of establishment of protein localizationGO:00702012420.032
regulation of mitotic sister chromatid segregationGO:0033047270.031
rho protein signal transductionGO:0007266260.031
positive regulation of hydrolase activityGO:00513453310.031
cellular macromolecular complex assemblyGO:00346223240.031
cation transportGO:00068123310.030
ribonucleoside catabolic processGO:00424544060.030
lipid biosynthetic processGO:00086101770.030
endomembrane system organizationGO:00102561960.030
cytoskeleton dependent cytokinesisGO:0061640220.029
vesicle localizationGO:0051648260.029
purine nucleoside catabolic processGO:00061523980.029
determination of adult lifespanGO:000834020.028
regulation of transcription factor import into nucleusGO:0042990390.028
histone h2a ubiquitinationGO:0033522170.028
synaptic vesicle endocytosisGO:004848820.028
regulation of meiotic cell cycleGO:005144540.028
regulation of intracellular protein transportGO:00331571230.028
neuron neuron synaptic transmissionGO:000727060.028
regulation of atpase activityGO:0043462250.028
response to abiotic stimulusGO:00096283360.027
biological adhesionGO:00226103310.027
secretionGO:00469032540.027
small molecule biosynthetic processGO:00442831570.027
regulation of nik nf kappab signalingGO:1901222110.027
multicellular organismal agingGO:001025930.027
locomotory behaviorGO:000762610.027
single organism nuclear importGO:19025931040.026
regulation of cellular component biogenesisGO:00440872810.026
nucleotide excision repairGO:0006289310.026
regulation of cellular amino acid metabolic processGO:000652160.026
nucleoside phosphate catabolic processGO:19012924120.026
anterior posterior axis specificationGO:000994820.026
positive regulation of atpase activityGO:0032781190.025
oogenesisGO:004847720.025
nitrogen compound transportGO:00717051910.025
chaperone mediated protein foldingGO:0061077130.025
cellular amino acid metabolic processGO:00065201160.025
positive regulation of intracellular protein transportGO:0090316760.024
cell developmentGO:00484683280.024
covalent chromatin modificationGO:00165692540.024
regulation of neurotransmitter levelsGO:0001505150.024
regulation of proteolysisGO:00301622930.024
Fly
positive regulation of nucleotide metabolic processGO:00459812300.024
positive regulation of mitotic cell cycleGO:0045931600.023
regulation of vesicle mediated transportGO:00606271300.023
signal transduction by phosphorylationGO:00230142970.023
nuclear importGO:00511701060.023
regulation of mapk cascadeGO:00434082620.023
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436300.022
positive regulation of proteasomal protein catabolic processGO:1901800350.022
jnk cascadeGO:0007254800.022
intermediate filament cytoskeleton organizationGO:0045104170.022
negative regulation of protein metabolic processGO:00512483910.022
Fly
cell cycle arrestGO:0007050710.022
regulation of locomotionGO:00400123290.021
establishment of spindle localizationGO:0051293120.021
organ formationGO:004864530.021
organophosphate catabolic processGO:00464344300.021
glycosyl compound catabolic processGO:19016584130.021
nucleus localizationGO:005164710.021
regulation of cellular response to stressGO:00801352440.021
regulation of cellular ketone metabolic processGO:0010565500.020
synaptic vesicle transportGO:004848950.020
single organism membrane organizationGO:00448022680.020
protein targeting to nucleusGO:00447441040.020
establishment of mitotic spindle localizationGO:004000180.020
regulation of ion transportGO:00432691890.020
protein import into nucleusGO:00066061040.019
secretion by cellGO:00329402260.019
exocytosisGO:0006887710.019
mitotic g2 dna damage checkpointGO:000709570.019
Fly
spermatid differentiationGO:004851540.019
protein maturationGO:00516042330.019
Fly
negative regulation of protein phosphorylationGO:00019331400.019
response to oxidative stressGO:00069791210.019
regulation of cytoplasmic transportGO:19036491490.018
alcohol metabolic processGO:00060661140.018
negative regulation of catalytic activityGO:00430863350.018
monovalent inorganic cation transportGO:00156721280.018
mitotic sister chromatid separationGO:0051306180.018
protein targetingGO:00066051870.018
optic nerve developmentGO:002155420.017
monocarboxylic acid biosynthetic processGO:0072330670.017
positive regulation of nik nf kappab signalingGO:1901224100.017
positive regulation of proteolysisGO:00458621420.017
negative regulation of protein modification processGO:00314002000.017
histone h2a monoubiquitinationGO:0035518110.016
regulation of protein import into nucleusGO:0042306780.016
positive regulation of cellular protein catabolic processGO:1903364370.016
neurotransmitter secretionGO:000726940.016
positive regulation of alcohol biosynthetic processGO:190293290.016
cell activationGO:00017752130.016
protein importGO:00170381300.016
intracellular protein transportGO:00068862700.016
regulation of nucleocytoplasmic transportGO:0046822980.016
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052350.015
protein acetylationGO:00064731160.015
positive regulation of cytoplasmic transportGO:1903651820.015
negative regulation of protein maturationGO:19033181420.015
Fly
regulation of endocytosisGO:0030100720.015
regulation of cellular component movementGO:00512703340.015
monoamine transportGO:0015844100.015
regulation of intracellular transportGO:00323861950.015
mitotic nuclear divisionGO:00070671190.015
organic hydroxy compound metabolic processGO:19016151470.015
cellular ketone metabolic processGO:0042180800.014
regulation of chromosome segregationGO:0051983440.014
hindbrain developmentGO:003090230.014
regulation of chromosome organizationGO:00330441030.014
chromosome separationGO:0051304230.014
positive regulation of steroid metabolic processGO:0045940130.014
cellular component morphogenesisGO:00329893140.014
regulation of protein localization to cell surfaceGO:2000008150.014
regulation of g2 m transition of mitotic cell cycleGO:0010389200.014
negative regulation of intracellular signal transductionGO:19025321830.014
synaptic transmissionGO:0007268610.014
cell cycle g1 s phase transitionGO:0044843800.014
cellular chemical homeostasisGO:00550821800.013
response to organic cyclic compoundGO:00140702040.013
dna conformation changeGO:00711031130.013
reproductive structure developmentGO:0048608550.013
Worm
negative regulation of apoptotic processGO:00430663160.013
nuclear migrationGO:000709710.013
transcription factor import into nucleusGO:0042991400.013
phagocytosisGO:0006909420.013
oocyte differentiationGO:000999420.013
neuromuscular junction developmentGO:000752830.013
chromatin modificationGO:00165682980.013
regulation of cell cycle g1 s phase transitionGO:1902806420.013
response to calcium ionGO:0051592460.012
nuclear transportGO:00511691790.012
carboxylic acid biosynthetic processGO:0046394970.012
reproductive processGO:00224141060.012
Worm
striated muscle tissue developmentGO:0014706590.012
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.012
Fly
neuron remodelingGO:001632220.012
positive regulation of cell proliferationGO:00082843010.012
cell part morphogenesisGO:00329901370.012
ncrna processingGO:0034470830.012
protein dna complex subunit organizationGO:0071824800.012
response to hormoneGO:00097251750.012
positive regulation of protein kinase a signalingGO:001073940.012
response to radiationGO:00093141510.012
positive regulation of chromatin modificationGO:1903310300.012
maintenance of locationGO:00512351120.012
eosinophil mediated immunityGO:000244720.012
chemical homeostasisGO:00488783060.012
cell morphogenesisGO:00009022960.011
cytoplasmic transportGO:00164823790.011
multicellular organismal reproductive processGO:0048609400.011
behaviorGO:00076101120.011
internal peptidyl lysine acetylationGO:0018393970.011
regulation of mitotic metaphase anaphase transitionGO:0030071260.011
negative regulation of multicellular organismal processGO:00512413170.011
negative regulation of programmed cell deathGO:00430693210.011
actin filament based processGO:00300292240.011
positive regulation of transcription factor import into nucleusGO:0042993250.011
blood vessel developmentGO:00015681720.011
regulation of cytokine productionGO:00018172320.011
regulation of nucleotide metabolic processGO:00061402690.011
steroid metabolic processGO:0008202940.011
stress activated protein kinase signaling cascadeGO:0031098940.010
regulation of microtubule based processGO:0032886740.010
negative regulation of protein kinase activityGO:0006469980.010
regulation of protein localization to nucleusGO:1900180850.010
muscle organ developmentGO:0007517560.010
blastocyst developmentGO:000182430.010
negative regulation of protein processingGO:00109551420.010
Fly
positive regulation of cell deathGO:00109422630.010
regulation of response to biotic stimulusGO:0002831550.010
response to uvGO:0009411730.010
organophosphate biosynthetic processGO:00904071630.010
sleepGO:003043120.010

COPS4 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.100
brain diseaseDOID:936730.100
central nervous system diseaseDOID:3311860.100
inherited metabolic disorderDOID:6552420.020
disease of metabolismDOID:00146672950.020
amino acid metabolic disorderDOID:9252500.013