Homo sapiens

41 known processes

SLC40A1

solute carrier family 40 (iron-regulated transporter), member 1

(Aliases: IREG1,SLC11A3,FPN1,MTP1,HFE4,MST079)

SLC40A1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
lipid metabolic processGO:00066293810.078
cellular ketone metabolic processGO:0042180800.069
post embryonic developmentGO:000979120.066
positive regulation of phosphorylationGO:00423273940.065
amine metabolic processGO:0009308440.062
cellular lipid metabolic processGO:00442553030.061
cellular amino acid metabolic processGO:00065201160.057
cellular amine metabolic processGO:0044106410.056
regulation of locomotionGO:00400123290.054
regulation of cellular amine metabolic processGO:0033238110.054
multicellular organismal agingGO:001025930.051
purine ribonucleoside metabolic processGO:00461284370.047
ras protein signal transductionGO:0007265730.047
cation transportGO:00068123310.047
positive regulation of cellular component organizationGO:00511303760.046
response to oxygen containing compoundGO:19017003690.046
oxidation reduction processGO:00551143960.045
purine ribonucleoside triphosphate metabolic processGO:00092054110.045
negative regulation of cellular protein metabolic processGO:00322693530.044
locomotory behaviorGO:000762610.044
purine nucleotide catabolic processGO:00061954050.044
regulation of cellular ketone metabolic processGO:0010565500.044
ribonucleoside catabolic processGO:00424544060.043
nucleoside phosphate catabolic processGO:19012924120.043
regulation of cellular amino acid metabolic processGO:000652160.043
nucleoside triphosphate catabolic processGO:00091433940.041
negative regulation of catalytic activityGO:00430863350.041
purine ribonucleotide catabolic processGO:00091544040.041
nucleotide catabolic processGO:00091664080.040
metal ion transportGO:00300012720.040
glycosyl compound catabolic processGO:19016584130.040
purine ribonucleoside triphosphate catabolic processGO:00092073910.039
determination of adult lifespanGO:000834020.039
single organism cellular localizationGO:19025803320.039
purine nucleoside triphosphate catabolic processGO:00091463920.039
nucleoside catabolic processGO:00091644080.038
defense responseGO:00069523150.038
chemical homeostasisGO:00488783060.038
regulation of transferase activityGO:00513383550.037
immune responseGO:00069553070.037
nucleoside triphosphate metabolic processGO:00091414220.037
positive regulation of cellular amine metabolic processGO:003324070.037
negative regulation of protein metabolic processGO:00512483910.037
ribonucleoside triphosphate catabolic processGO:00092033910.037
organophosphate catabolic processGO:00464344300.037
regulation of cell differentiationGO:00455953930.036
oogenesisGO:004847720.036
ribonucleoside triphosphate metabolic processGO:00091994120.036
positive regulation of catabolic processGO:00098963100.035
purine nucleoside catabolic processGO:00061523980.035
regulation of kinase activityGO:00435493140.034
positive regulation of cellular amino acid metabolic processGO:004576430.034
purine nucleoside triphosphate metabolic processGO:00091444120.034
purine containing compound catabolic processGO:00725234110.034
response to other organismGO:00517072610.034
positive regulation of transportGO:00510503360.034
small gtpase mediated signal transductionGO:0007264780.034
response to biotic stimulusGO:00096072760.033
regulation of protein localizationGO:00328802960.033
positive regulation of cellular catabolic processGO:00313312840.033
ribonucleotide catabolic processGO:00092614050.033
single organism membrane organizationGO:00448022680.032
segmentationGO:003528240.032
response to abiotic stimulusGO:00096283360.032
regulation of purine nucleotide metabolic processGO:19005422640.031
purine ribonucleoside catabolic processGO:00461303980.031
regulation of cellular component movementGO:00512703340.031
negative regulation of phosphate metabolic processGO:00459362670.031
lipid biosynthetic processGO:00086101770.031
cellular response to endogenous stimulusGO:00714953360.031
positive regulation of hydrolase activityGO:00513453310.031
membrane organizationGO:00610242920.031
regulation of mapk cascadeGO:00434082620.031
positive regulation of cell deathGO:00109422630.031
regulation of protein kinase activityGO:00458592890.030
regulation of cell motilityGO:20001452990.030
vesicle mediated transportGO:00161923710.029
regulation of cell migrationGO:00303342890.029
response to external biotic stimulusGO:00432072610.029
secretionGO:00469032540.029
ion transmembrane transportGO:00342203380.028
positive regulation of developmental processGO:00510943140.028
anatomical structure formation involved in morphogenesisGO:00486462840.028
Mouse
negative regulation of phosphorus metabolic processGO:00105632670.027
system processGO:00030083490.027
cellular component morphogenesisGO:00329893140.027
cytoplasmic transportGO:00164823790.027
cellular response to oxygen containing compoundGO:19017012760.027
positive regulation of purine nucleotide metabolic processGO:19005442270.027
cell developmentGO:00484683280.027
Zebrafish
protein maturationGO:00516042330.027
ion homeostasisGO:00508012300.027
positive regulation of immune system processGO:00026842830.026
positive regulation of cell proliferationGO:00082843010.026
negative regulation of multicellular organismal processGO:00512413170.026
guanosine containing compound metabolic processGO:19010682440.025
gtp catabolic processGO:00061842370.025
actin filament based processGO:00300292240.025
positive regulation of nucleotide metabolic processGO:00459812300.025
protein catabolic processGO:00301633250.025
transmembrane transportGO:00550853990.025
guanosine containing compound catabolic processGO:19010692390.025
enzyme linked receptor protein signaling pathwayGO:00071673030.025
cation transmembrane transportGO:00986552380.025
gtp metabolic processGO:00460392390.025
cytokine productionGO:00018162470.024
secretion by cellGO:00329402260.024
negative regulation of cellular component organizationGO:00511292350.024
neuromuscular junction developmentGO:000752830.024
carbohydrate metabolic processGO:00059752070.024
single organism carbohydrate metabolic processGO:00447231930.024
innate immune responseGO:00450871780.024
cell projection organizationGO:00300302520.024
regulation of cell cycleGO:00517263930.024
nervous system developmentGO:00073992930.023
cellular macromolecule catabolic processGO:00442653800.023
regenerationGO:003109940.023
positive regulation of programmed cell deathGO:00430682490.023
female gamete generationGO:000729220.023
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.023
regulation of anatomical structure morphogenesisGO:00226032860.023
signal transduction by phosphorylationGO:00230142970.023
cellular macromolecular complex assemblyGO:00346223240.023
regulation of nucleotide metabolic processGO:00061402690.023
response to organic cyclic compoundGO:00140702040.023
response to hormoneGO:00097251750.023
regulation of intracellular transportGO:00323861950.023
biological adhesionGO:00226103310.022
regulation of response to external stimulusGO:00321012220.022
response to cytokineGO:00340972320.022
regulation of cytokine productionGO:00018172320.022
negative regulation of developmental processGO:00510932470.022
rho protein signal transductionGO:0007266260.022
regulation of purine nucleotide catabolic processGO:00331212050.022
negative regulation of hydrolase activityGO:00513461820.022
regulation of protein transportGO:00512232130.022
organic hydroxy compound metabolic processGO:19016151470.022
protein ubiquitinationGO:00165673140.022
cell morphogenesisGO:00009022960.022
reactive oxygen species metabolic processGO:0072593750.022
intracellular protein transportGO:00068862700.022
regulation of cellular response to stressGO:00801352440.022
immune effector processGO:00022521590.022
positive regulation of cytokine productionGO:00018191670.022
response to nitrogen compoundGO:19016981840.022
regulation of nucleoside metabolic processGO:00091182090.022
small molecule biosynthetic processGO:00442831570.022
immune system developmentGO:00025201950.022
Zebrafish Mouse
negative regulation of cell proliferationGO:00082852280.021
protein localization to organelleGO:00333652800.021
response to lipidGO:00339932060.021
cardiovascular system developmentGO:00723582620.021
apoptotic signaling pathwayGO:00971902680.021
circulatory system developmentGO:00723592620.021
regulation of nucleotide catabolic processGO:00308112050.021
alcohol metabolic processGO:00060661140.021
negative regulation of locomotionGO:00400131180.021
organonitrogen compound biosynthetic processGO:19015662000.020
negative regulation of intracellular signal transductionGO:19025321830.020
mapk cascadeGO:00001652880.020
epithelium developmentGO:00604292270.020
Mouse
negative regulation of programmed cell deathGO:00430693210.020
Mouse
growthGO:00400072020.020
memoryGO:000761330.020
response to organonitrogen compoundGO:00102431560.020
cellular protein catabolic processGO:00442572610.020
negative regulation of transportGO:00510511760.020
regulation of immune responseGO:00507762010.020
negative regulation of protein modification processGO:00314002000.020
positive regulation of nucleotide catabolic processGO:00308131850.020
positive regulation of protein phosphorylationGO:00019343130.020
mitotic cell cycleGO:00002783260.020
positive regulation of purine nucleotide catabolic processGO:00331231850.020
negative regulation of phosphorylationGO:00423261740.019
hindbrain developmentGO:003090230.019
dephosphorylationGO:00163112090.019
regulation of establishment of protein localizationGO:00702012420.019
positive regulation of apoptotic processGO:00430652460.019
regulation of gtp catabolic processGO:00331241800.019
cell adhesionGO:00071553250.019
regulation of secretionGO:00510461940.019
regulation of proteolysisGO:00301622930.019
protein oligomerizationGO:00512591730.019
positive regulation of locomotionGO:00400171860.019
positive regulation of nucleoside metabolic processGO:00459791860.019
cation homeostasisGO:00550801890.019
protein processingGO:00164852260.019
positive regulation of cell differentiationGO:00455972110.018
inorganic cation transmembrane transportGO:00986621940.018
cellular homeostasisGO:00197251960.018
negative regulation of cell deathGO:00605483450.018
Mouse
vasculature developmentGO:00019441810.018
inorganic ion transmembrane transportGO:00986602310.018
endomembrane system organizationGO:00102561960.018
regulation of secretion by cellGO:19035301770.018
response to inorganic substanceGO:00100351270.018
Zebrafish Mouse
cellular response to dna damage stimulusGO:00069743790.018
cellular chemical homeostasisGO:00550821800.018
cell activationGO:00017752130.018
proteolysis involved in cellular protein catabolic processGO:00516032440.018
oocyte developmentGO:004859910.018
negative regulation of cellular amine metabolic processGO:003323930.018
regulation of endopeptidase activityGO:00525481700.017
regulation of ras protein signal transductionGO:00465781550.017
organophosphate biosynthetic processGO:00904071630.017
posttranscriptional regulation of gene expressionGO:00106082130.017
regulation of multi organism processGO:00439001570.017
hemopoiesisGO:00300971800.017
Zebrafish
positive regulation of kinase activityGO:00336742040.017
endocytosisGO:00068971590.017
carbohydrate derivative biosynthetic processGO:19011372070.017
negative regulation of cell migrationGO:00303361020.017
regulation of ion transportGO:00432691890.017
cyclic nucleotide metabolic processGO:0009187820.017
anterior posterior axis specificationGO:000994820.017
protein modification by small protein conjugationGO:00324463420.017
positive regulation of cell motilityGO:20001471770.017
anterior posterior axis specification embryoGO:000859520.017
epithelial cell differentiationGO:00308551410.017
response to woundingGO:00096111680.016
cellular response to growth factor stimulusGO:00713631970.016
regulation of sequence specific dna binding transcription factor activityGO:00510902110.016
response to bacteriumGO:00096171440.016
metal ion homeostasisGO:00550651690.016
spermatid differentiationGO:004851540.016
regulation of i kappab kinase nf kappab signalingGO:00431221620.016
monocarboxylic acid metabolic processGO:00327871850.016
nucleocytoplasmic transportGO:00069131760.016
plasma membrane organizationGO:00070091150.016
regulation of gtpase activityGO:00430871800.016
nerve developmentGO:002167540.016
nitrogen compound transportGO:00717051910.016
regulation of cellular component biogenesisGO:00440872810.016
regulation of growthGO:00400081650.016
sequestering of metal ionGO:0051238240.016
protein localization to membraneGO:00726571600.016
maintenance of locationGO:00512351120.016
positive regulation of ras gtpase activityGO:00323201170.016
hematopoietic or lymphoid organ developmentGO:00485341860.016
Zebrafish Mouse
anion transportGO:00068201610.016
cellular protein complex assemblyGO:00436231880.016
blood vessel morphogenesisGO:00485141620.016
negative regulation of protein phosphorylationGO:00019331400.016
cellular metal ion homeostasisGO:00068751460.016
inner ear morphogenesisGO:004247240.015
regulation of cytoskeleton organizationGO:00514931770.015
negative regulation of cellular amino acid metabolic processGO:004576320.015
regulation of cell developmentGO:00602841610.015
positive regulation of protein transportGO:00512221350.015
negative regulation of apoptotic processGO:00430663160.015
Mouse
positive regulation of cell migrationGO:00303351720.015
positive regulation of gtpase activityGO:00435471660.015
blastoderm segmentationGO:000735020.015
positive regulation of gtp catabolic processGO:00331261660.015
positive regulation of transferase activityGO:00513472270.015
purine ribonucleoside monophosphate metabolic processGO:00091671860.015
tripartite regional subdivisionGO:000735120.015
epithelial cell proliferationGO:00506731280.015
positive regulation of cellular component movementGO:00512721810.015
fatty acid metabolic processGO:00066311150.015
peripheral nervous system developmentGO:000742220.015
morphogenesis of embryonic epitheliumGO:001633140.015
interspecies interaction between organismsGO:00444191560.015
rhythmic behaviorGO:000762220.015
g protein coupled receptor signaling pathwayGO:00071862070.015
divalent inorganic cation homeostasisGO:00725071360.015
cellular response to cytokine stimulusGO:00713451810.015
regulation of cell cycle processGO:00105642660.015
regulation of cytoplasmic transportGO:19036491490.015
adult locomotory behaviorGO:000834410.015
positive regulation of immune responseGO:00507781590.015
protein targetingGO:00066051870.015
neurotransmitter secretionGO:000726940.015
phospholipid metabolic processGO:0006644990.014
tube developmentGO:00352951250.014
regulation of peptidase activityGO:00525471800.014
regulation of defense responseGO:00313471540.014
response to virusGO:00096151260.014
regulation of cell growthGO:00015581350.014
cell growthGO:00160491600.014
nuclear transportGO:00511691790.014
defense response to other organismGO:00985421290.014
spermatid developmentGO:000728640.014
regulation of cell adhesionGO:00301551660.014
modification dependent macromolecule catabolic processGO:00436322120.014
multi organism cellular processGO:00447641560.014
organ morphogenesisGO:00098871470.014
Mouse
positive regulation of protein kinase activityGO:00458601900.014
reactive oxygen species biosynthetic processGO:190340940.014
positive regulation of synaptic transmissionGO:005080640.014
positive regulation of proteolysisGO:00458621420.014
regulation of hormone levelsGO:00108171250.014
ubiquitin dependent protein catabolic processGO:00065112060.014
regulation of protein catabolic processGO:00421761550.014
negative regulation of cell differentiationGO:00455961710.014
protein autophosphorylationGO:00467771230.014
cellular cation homeostasisGO:00300031630.014
negative regulation of cell cycleGO:00457861930.014
regulation of small gtpase mediated signal transductionGO:00510561560.014
response to metal ionGO:0010038840.014
Zebrafish Mouse
regulation of protein processingGO:00706131500.014
chromatin organizationGO:00063253510.014
symbiosis encompassing mutualism through parasitismGO:00444031560.014
regulation of protein maturationGO:19033171500.014
generation of neuronsGO:00486991520.014
negative regulation of immune system processGO:00026831360.014
cofactor metabolic processGO:0051186870.014
regulation of apoptotic signaling pathwayGO:20012331750.013
activation of immune responseGO:00022531140.013
response to growth factorGO:00708482050.013
reactive nitrogen species metabolic processGO:200105730.013
lipid catabolic processGO:0016042840.013
negative regulation of protein processingGO:00109551420.013
regulation of protein serine threonine kinase activityGO:00719001790.013
oocyte differentiationGO:000999420.013
positive regulation of mapk cascadeGO:00434101900.013
wnt signaling pathwayGO:00160551560.013
regulation of synaptic plasticityGO:004816730.013
neurological system processGO:00508771630.013
metencephalon developmentGO:002203720.013
cardiac muscle cell contractionGO:008600340.013
thymus developmentGO:004853830.013
negative regulation of cell motilityGO:20001461040.013
purine nucleoside monophosphate metabolic processGO:00091261860.013
regulation of vesicle mediated transportGO:00606271300.013
circadian behaviorGO:004851220.013
cellular ion homeostasisGO:00068731680.013
carboxylic acid biosynthetic processGO:0046394970.013
actin cytoskeleton organizationGO:00300362070.013
covalent chromatin modificationGO:00165692540.013
neurogenesisGO:00220081690.013
mitotic cell cycle processGO:19030472860.013
negative regulation of proteolysisGO:00458611320.013
embryo developmentGO:00097901230.013
Zebrafish
negative regulation of catabolic processGO:00098951040.013
modification dependent protein catabolic processGO:00199412090.013
actin mediated cell contractionGO:0070252120.013
regulation of response to woundingGO:19030341010.013
glycerolipid metabolic processGO:00464861070.013
histone modificationGO:00165702510.013
cell projection morphogenesisGO:00488581290.013
chromatin modificationGO:00165682980.013
regulation of intracellular protein transportGO:00331571230.013
regulation of ras gtpase activityGO:00323181280.013
establishment of protein localization to organelleGO:00725941720.013
cell fate determinationGO:000170930.013
glycoprotein metabolic processGO:00091001100.013
cell part morphogenesisGO:00329901370.013
regulation of dna metabolic processGO:00510521530.012
positive regulation of protein serine threonine kinase activityGO:00719021190.012
embryonic epithelial tube formationGO:000183840.012
peptidyl tyrosine phosphorylationGO:00181081700.012
ameboidal type cell migrationGO:00016671350.012
response to axon injuryGO:004867810.012
regulation of neurotransmitter secretionGO:004692830.012
regulation of neural precursor cell proliferationGO:200017740.012
rna processingGO:00063962550.012
cell substrate adhesionGO:00315891320.012
glycerophospholipid metabolic processGO:0006650840.012
blood circulationGO:00080151130.012
negative regulation of protein maturationGO:19033181420.012
endosomal transportGO:00161971290.012
regulation of bindingGO:00510981110.012
response to extracellular stimulusGO:0009991850.012
positive regulation of organelle organizationGO:00106381950.012
matingGO:000761810.012
regulation of reactive oxygen species biosynthetic processGO:190342630.012
regulation of protein complex assemblyGO:00432541470.012
ribonucleoside monophosphate metabolic processGO:00091611870.012
neuroblast proliferationGO:000740540.012
nucleoside monophosphate metabolic processGO:00091231910.012
protein homooligomerizationGO:00512601000.012
associative learningGO:000830610.012
proteasomal protein catabolic processGO:00104981760.012
regulation of epithelial cell proliferationGO:00506781130.012
negative regulation of synaptic transmissionGO:005080520.012
compound eye developmentGO:004874910.012
negative regulation of organelle organizationGO:00106391260.012
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.012
regulation of homeostatic processGO:00328441210.012
rna interferenceGO:001624640.012
angiogenesisGO:00015251470.012
sulfur compound metabolic processGO:00067901010.012
wound healingGO:00420601150.012
negative regulation of cellular component movementGO:00512711060.012
atp metabolic processGO:00460341760.012
negative regulation of growthGO:0045926970.012
regulation of viral processGO:00507921030.012
regulation of cell morphogenesisGO:00226041530.012
regulation of mitotic cell cycleGO:00073461890.012
actin filament based movementGO:0030048170.012
cerebellum developmentGO:002154920.012
divalent inorganic cation transportGO:00725111580.012
negative regulation of transferase activityGO:00513481240.012
regulation of actin filament based processGO:00329701410.012
microtubule cytoskeleton organizationGO:00002261760.012
sensory perception of smellGO:000760820.012
cell cycle phase transitionGO:00447701730.012
protein localization to plasma membraneGO:0072659930.012
organic acid biosynthetic processGO:0016053970.011
organelle assemblyGO:00709251760.011
response to oxidative stressGO:00069791210.011
cellular response to hormone stimulusGO:00328701250.011
microtubule based processGO:00070172100.011
response to radiationGO:00093141510.011
ossificationGO:00015031210.011
cell type specific apoptotic processGO:00972851250.011
motor neuron axon guidanceGO:000804520.011
myeloid cell differentiationGO:00300991170.011
Zebrafish
circulatory system processGO:00030131130.011
cell divisionGO:00513011680.011
positive regulation of secretion by cellGO:19035321080.011
limbic system developmentGO:002176130.011
i kappab kinase nf kappab signalingGO:00072491660.011
coagulationGO:0050817780.011
viral processGO:00160321460.011
muscle contractionGO:0006936730.011
regulation of reactive oxygen species metabolic processGO:2000377410.011
cell projection assemblyGO:00300311260.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.011
cellular component disassemblyGO:0022411920.011
nuclear importGO:00511701060.011
neuron developmentGO:00486661130.011
tissue regenerationGO:004224630.011
organic anion transportGO:00157111030.011
coenzyme metabolic processGO:0006732650.011
negative regulation of blood pressureGO:004577630.011
response to nutrient levelsGO:0031667810.011
regulation of transmembrane transportGO:00347621390.011
organ formationGO:004864530.011
taxisGO:00423301570.011
glycoprotein biosynthetic processGO:0009101910.011
negative regulation of cellular catabolic processGO:0031330830.011
nucleoside monophosphate catabolic processGO:00091251590.011
cellular response to external stimulusGO:00714961110.011
positive regulation of cellular component biogenesisGO:00440891580.011
chemotaxisGO:00069351570.011
protein localization to nucleusGO:00345041360.011
organelle fissionGO:00482851490.011
regulation of wnt signaling pathwayGO:00301111230.011
photoreceptor cell differentiationGO:004653020.011
neural tube formationGO:000184130.011
regulation of epithelial cell migrationGO:0010632930.011
blood vessel developmentGO:00015681720.011
mitochondrion organizationGO:00070051560.010
cellular divalent inorganic cation homeostasisGO:00725031280.010
cellular response to lipidGO:00713961270.010
regulation of anatomical structure sizeGO:00900661010.010
epithelial cell migrationGO:00106311190.010
lipid modificationGO:0030258840.010
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.010
positive regulation of intracellular transportGO:00323881040.010
cell morphogenesis involved in differentiationGO:00009041440.010
regulation of innate immune responseGO:0045088970.010
ribonucleoside monophosphate catabolic processGO:00091581580.010
regulation of immune effector processGO:0002697910.010
syncytium formation by plasma membrane fusionGO:000076820.010
cellular carbohydrate metabolic processGO:0044262840.010
positive regulation of reactive oxygen species metabolic processGO:2000379240.010
negative regulation of peptidase activityGO:0010466910.010
atp catabolic processGO:00062001570.010
regulation of cysteine type endopeptidase activityGO:20001161270.010
epithelium migrationGO:00901321190.010
response to fungusGO:000962040.010
cellular response to nitrogen compoundGO:19016991440.010
purine nucleoside monophosphate catabolic processGO:00091281580.010
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.010
morphogenesis of a polarized epitheliumGO:000173830.010
positive regulation of cell cycleGO:00457871400.010
divalent metal ion transportGO:00708381520.010
t cell differentiation in thymusGO:003307740.010
muscle system processGO:0003012810.010
calcium ion homeostasisGO:00550741220.010
receptor metabolic processGO:0043112810.010

SLC40A1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.078
inherited metabolic disorderDOID:6552420.030
nervous system diseaseDOID:8634310.021
sensory system diseaseDOID:00501552030.021
cardiovascular system diseaseDOID:12871060.020
musculoskeletal system diseaseDOID:172230.018
eye and adnexa diseaseDOID:14921500.017
eye diseaseDOID:56141490.017
disease of cellular proliferationDOID:145661740.017
cancerDOID:1621670.016
central nervous system diseaseDOID:3311860.016
acquired metabolic diseaseDOID:0060158580.015
immune system diseaseDOID:29141550.015
organ system cancerDOID:00506861640.014
retinal diseaseDOID:56791180.014
connective tissue diseaseDOID:651090.012
neurodegenerative diseaseDOID:12891020.011
hematopoietic system diseaseDOID:741000.010
metal metabolism disorderDOID:896190.003