Homo sapiens

29 known processes

SPIRE1

spire homolog 1 (Drosophila)

(Aliases: MGC150621,MGC150622,Spir-1)

SPIRE1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.072
ribonucleoside catabolic processGO:00424544060.065
nucleotide catabolic processGO:00091664080.065
purine nucleotide catabolic processGO:00061954050.064
ras protein signal transductionGO:0007265730.064
small gtpase mediated signal transductionGO:0007264780.060
purine ribonucleoside metabolic processGO:00461284370.060
cellular amino acid metabolic processGO:00065201160.060
nucleoside triphosphate metabolic processGO:00091414220.058
purine containing compound catabolic processGO:00725234110.058
organophosphate catabolic processGO:00464344300.058
cellular ketone metabolic processGO:0042180800.057
purine nucleoside triphosphate catabolic processGO:00091463920.057
purine ribonucleoside triphosphate metabolic processGO:00092054110.057
ribonucleoside triphosphate metabolic processGO:00091994120.056
amine metabolic processGO:0009308440.056
purine ribonucleotide catabolic processGO:00091544040.054
nucleoside catabolic processGO:00091644080.054
ribonucleoside triphosphate catabolic processGO:00092033910.054
glycosyl compound catabolic processGO:19016584130.053
purine ribonucleoside triphosphate catabolic processGO:00092073910.053
ribonucleotide catabolic processGO:00092614050.053
purine nucleoside triphosphate metabolic processGO:00091444120.051
oogenesisGO:004847720.051
Fly
guanosine containing compound metabolic processGO:19010682440.050
female gamete generationGO:000729220.049
Fly
multicellular organismal agingGO:001025930.049
nucleoside phosphate catabolic processGO:19012924120.048
locomotory behaviorGO:000762610.048
gtp metabolic processGO:00460392390.048
cell developmentGO:00484683280.047
Fly
actin filament based processGO:00300292240.047
cellular amine metabolic processGO:0044106410.047
purine nucleoside catabolic processGO:00061523980.047
positive regulation of catabolic processGO:00098963100.047
cell morphogenesisGO:00009022960.046
cytoplasmic transportGO:00164823790.046
purine ribonucleoside catabolic processGO:00461303980.045
determination of adult lifespanGO:000834020.045
positive regulation of gtpase activityGO:00435471660.045
cellular macromolecule catabolic processGO:00442653800.044
regulation of cellular amine metabolic processGO:0033238110.044
positive regulation of cellular catabolic processGO:00313312840.044
regulation of cellular ketone metabolic processGO:0010565500.043
cellular lipid metabolic processGO:00442553030.043
inorganic ion transmembrane transportGO:00986602310.043
nucleoside triphosphate catabolic processGO:00091433940.042
negative regulation of phosphate metabolic processGO:00459362670.042
negative regulation of catalytic activityGO:00430863350.041
regulation of cellular amino acid metabolic processGO:000652160.041
cation transportGO:00068123310.040
lipid metabolic processGO:00066293810.040
regulation of nucleotide metabolic processGO:00061402690.040
single organism membrane organizationGO:00448022680.039
rho protein signal transductionGO:0007266260.039
single organism cellular localizationGO:19025803320.038
cellular component morphogenesisGO:00329893140.038
protein catabolic processGO:00301633250.038
regulation of anatomical structure morphogenesisGO:00226032860.038
positive regulation of transportGO:00510503360.037
regulation of purine nucleotide metabolic processGO:19005422640.037
positive regulation of hydrolase activityGO:00513453310.037
blastoderm segmentationGO:000735020.037
Fly
guanosine containing compound catabolic processGO:19010692390.037
regulation of nucleotide catabolic processGO:00308112050.037
metal ion transportGO:00300012720.036
biological adhesionGO:00226103310.035
cation transmembrane transportGO:00986552380.034
mitotic cell cycleGO:00002783260.034
negative regulation of cellular protein metabolic processGO:00322693530.034
regulation of cellular component biogenesisGO:00440872810.034
Fly
regulation of gtp catabolic processGO:00331241800.033
regulation of protein localizationGO:00328802960.033
membrane organizationGO:00610242920.032
gtp catabolic processGO:00061842370.032
maintenance of locationGO:00512351120.032
positive regulation of cellular amino acid metabolic processGO:004576430.032
positive regulation of cellular component organizationGO:00511303760.031
Fly
nervous system developmentGO:00073992930.031
segmentationGO:003528240.031
Fly
regulation of purine nucleotide catabolic processGO:00331212050.031
negative regulation of protein metabolic processGO:00512483910.031
anterior posterior axis specificationGO:000994820.031
Fly
memoryGO:000761330.031
response to abiotic stimulusGO:00096283360.031
neuromuscular junction developmentGO:000752830.030
regulation of cell cycleGO:00517263930.030
positive regulation of purine nucleotide catabolic processGO:00331231850.030
regulation of kinase activityGO:00435493140.030
system processGO:00030083490.030
actin cytoskeleton organizationGO:00300362070.030
regulation of gtpase activityGO:00430871800.030
inorganic cation transmembrane transportGO:00986621940.030
regulation of ras protein signal transductionGO:00465781550.029
positive regulation of purine nucleotide metabolic processGO:19005442270.029
positive regulation of phosphorylationGO:00423273940.029
regulation of nucleoside metabolic processGO:00091182090.029
cellular macromolecular complex assemblyGO:00346223240.028
Fly
ion transmembrane transportGO:00342203380.028
regulation of cellular response to stressGO:00801352440.028
glycerolipid metabolic processGO:00464861070.027
monovalent inorganic cation transportGO:00156721280.027
enzyme linked receptor protein signaling pathwayGO:00071673030.027
negative regulation of phosphorus metabolic processGO:00105632670.027
cellular protein catabolic processGO:00442572610.027
mapk cascadeGO:00001652880.027
signal transduction by phosphorylationGO:00230142970.027
protein localization to organelleGO:00333652800.027
regulation of transferase activityGO:00513383550.027
regulation of establishment of protein localizationGO:00702012420.026
endomembrane system organizationGO:00102561960.026
transmembrane transportGO:00550853990.026
negative regulation of cellular amine metabolic processGO:003323930.026
microtubule based processGO:00070172100.026
oocyte differentiationGO:000999420.026
Fly
regulation of mapk cascadeGO:00434082620.025
negative regulation of apoptotic processGO:00430663160.025
positive regulation of nucleotide metabolic processGO:00459812300.025
chemical homeostasisGO:00488783060.025
cell adhesionGO:00071553250.025
regulation of cell differentiationGO:00455953930.025
response to oxygen containing compoundGO:19017003690.025
regulation of synaptic plasticityGO:004816730.025
regulation of locomotionGO:00400123290.024
dephosphorylationGO:00163112090.024
regulation of small gtpase mediated signal transductionGO:00510561560.024
regenerationGO:003109940.024
positive regulation of cell deathGO:00109422630.024
single organismal cell cell adhesionGO:00163371480.024
positive regulation of gtp catabolic processGO:00331261660.023
carbohydrate metabolic processGO:00059752070.023
positive regulation of cellular amine metabolic processGO:003324070.023
protein localization to membraneGO:00726571600.023
generation of neuronsGO:00486991520.023
cell projection organizationGO:00300302520.023
regulation of proteolysisGO:00301622930.023
positive regulation of kinase activityGO:00336742040.023
proteolysis involved in cellular protein catabolic processGO:00516032440.023
intracellular protein transportGO:00068862700.023
regulation of cellular component movementGO:00512703340.023
regulation of protein kinase activityGO:00458592890.023
positive regulation of developmental processGO:00510943140.022
anatomical structure formation involved in morphogenesisGO:00486462840.022
Fly
neurogenesisGO:00220081690.022
negative regulation of cellular component organizationGO:00511292350.022
negative regulation of cellular amino acid metabolic processGO:004576320.022
regulation of cell motilityGO:20001452990.022
negative regulation of programmed cell deathGO:00430693210.022
cellular response to dna damage stimulusGO:00069743790.022
single organism cell adhesionGO:00986021790.022
regulation of cytoskeleton organizationGO:00514931770.022
Fly
single organism carbohydrate metabolic processGO:00447231930.022
endosomal transportGO:00161971290.022
modification dependent protein catabolic processGO:00199412090.021
positive regulation of protein phosphorylationGO:00019343130.021
epithelium developmentGO:00604292270.021
Fly
protein modification by small protein conjugationGO:00324463420.021
mitotic cell cycle processGO:19030472860.021
growthGO:00400072020.021
oocyte developmentGO:004859910.021
Fly
positive regulation of nucleotide catabolic processGO:00308131850.021
spermatid differentiationGO:004851540.021
tripartite regional subdivisionGO:000735120.021
Fly
spermatid developmentGO:000728640.021
lipid biosynthetic processGO:00086101770.021
regulation of cell morphogenesisGO:00226041530.021
wnt signaling pathwayGO:00160551560.020
organonitrogen compound biosynthetic processGO:19015662000.020
microtubule cytoskeleton organizationGO:00002261760.020
positive regulation of nucleoside metabolic processGO:00459791860.020
negative regulation of cell deathGO:00605483450.020
associative learningGO:000830610.020
neurological system processGO:00508771630.020
positive regulation of ras gtpase activityGO:00323201170.019
regulation of protein catabolic processGO:00421761550.019
cardiac muscle cell contractionGO:008600340.019
positive regulation of synaptic transmissionGO:005080640.019
positive regulation of transferase activityGO:00513472270.019
somatic stem cell divisionGO:004810310.019
adult locomotory behaviorGO:000834410.019
cell growthGO:00160491600.019
ubiquitin dependent protein catabolic processGO:00065112060.019
neuron differentiationGO:00301821380.019
oxidation reduction processGO:00551143960.019
regulation of neurotransmitter secretionGO:004692830.019
posttranscriptional regulation of gene expressionGO:00106082130.019
regulation of protein transportGO:00512232130.018
cellular homeostasisGO:00197251960.018
regulation of growthGO:00400081650.018
nitrogen compound transportGO:00717051910.018
immune responseGO:00069553070.018
negative regulation of multicellular organismal processGO:00512413170.018
negative regulation of hydrolase activityGO:00513461820.018
modification dependent macromolecule catabolic processGO:00436322120.018
mitochondrion organizationGO:00070051560.018
cell junction organizationGO:0034330790.018
negative regulation of intracellular signal transductionGO:19025321830.018
regulation of cell cycle processGO:00105642660.018
nuclear transportGO:00511691790.018
neuroblast proliferationGO:000740540.018
vesicle mediated transportGO:00161923710.018
positive regulation of locomotionGO:00400171860.018
establishment of protein localization to membraneGO:00901501210.018
positive regulation of mapk cascadeGO:00434101900.018
reactive oxygen species biosynthetic processGO:190340940.018
lung alveolus developmentGO:004828640.018
reactive oxygen species metabolic processGO:0072593750.018
epithelial cell differentiationGO:00308551410.018
Fly
response to growth factorGO:00708482050.017
ion homeostasisGO:00508012300.017
organophosphate biosynthetic processGO:00904071630.017
anterior posterior axis specification embryoGO:000859520.017
Fly
neurotransmitter secretionGO:000726940.017
protein localization to plasma membraneGO:0072659930.017
cell fate determinationGO:000170930.017
regulation of cell developmentGO:00602841610.017
negative regulation of phosphorylationGO:00423261740.017
negative regulation of developmental processGO:00510932470.017
photoreceptor cell differentiationGO:004653020.017
regulation of protein serine threonine kinase activityGO:00719001790.017
regulation of intracellular transportGO:00323861950.017
protein processingGO:00164852260.017
organelle assemblyGO:00709251760.017
positive regulation of protein kinase activityGO:00458601900.017
negative regulation of protein modification processGO:00314002000.016
nucleocytoplasmic transportGO:00069131760.016
cellular response to endogenous stimulusGO:00714953360.016
hindbrain developmentGO:003090230.016
morphogenesis of embryonic epitheliumGO:001633140.016
protein targetingGO:00066051870.016
stem cell divisionGO:001714520.016
positive regulation of apoptotic processGO:00430652460.016
regulation of cell migrationGO:00303342890.016
regulation of ras gtpase activityGO:00323181280.016
cellular response to oxygen containing compoundGO:19017012760.016
apoptotic signaling pathwayGO:00971902680.016
protein autophosphorylationGO:00467771230.016
cellular chemical homeostasisGO:00550821800.016
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.016
defense responseGO:00069523150.016
actin filament based movementGO:0030048170.016
cell part morphogenesisGO:00329901370.016
establishment or maintenance of microtubule cytoskeleton polarityGO:003095120.015
secretion by cellGO:00329402260.015
anion transportGO:00068201610.015
regulation of cytoplasmic transportGO:19036491490.015
cell cell signalingGO:00072671550.015
protein ubiquitinationGO:00165673140.015
regulation of ion transportGO:00432691890.015
phospholipid metabolic processGO:0006644990.015
endocytosisGO:00068971590.015
carbohydrate derivative biosynthetic processGO:19011372070.015
establishment or maintenance of cytoskeleton polarityGO:003095230.015
protein maturationGO:00516042330.015
release of cytoplasmic sequestered nf kappabGO:000858840.015
response to woundingGO:00096111680.015
plasma membrane organizationGO:00070091150.015
regulation of membrane potentialGO:0042391950.015
organ morphogenesisGO:00098871470.015
regulation of actin cytoskeleton organizationGO:00329561160.015
Fly
regulation of response to external stimulusGO:00321012220.015
regulation of neural precursor cell proliferationGO:200017740.015
regulation of mitotic cell cycleGO:00073461890.015
cellular protein complex assemblyGO:00436231880.015
Fly
regulation of cell projection organizationGO:00313441070.015
regulation of peptidase activityGO:00525471800.014
regulation of wnt signaling pathwayGO:00301111230.014
positive regulation of cell motilityGO:20001471770.014
regulation of cell growthGO:00015581350.014
regulation of reactive oxygen species biosynthetic processGO:190342630.014
secretionGO:00469032540.014
regulation of intracellular protein transportGO:00331571230.014
regulation of vesicle mediated transportGO:00606271300.014
cell divisionGO:00513011680.014
nucleus localizationGO:005164710.014
response to hormoneGO:00097251750.014
response to axon injuryGO:004867810.014
negative regulation of catabolic processGO:00098951040.014
proteasomal protein catabolic processGO:00104981760.014
syncytium formation by plasma membrane fusionGO:000076820.014
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.014
positive regulation of programmed cell deathGO:00430682490.014
regulation of transmembrane transportGO:00347621390.014
negative regulation of protein phosphorylationGO:00019331400.014
organ formationGO:004864530.014
regulation of cell adhesionGO:00301551660.014
cellular response to growth factor stimulusGO:00713631970.014
long term memoryGO:000761620.014
neuron developmentGO:00486661130.014
negative regulation of transferase activityGO:00513481240.014
response to other organismGO:00517072610.014
establishment of protein localization to plasma membraneGO:0090002680.013
peripheral nervous system developmentGO:000742220.013
embryonic epithelial tube formationGO:000183840.013
cardiovascular system developmentGO:00723582620.013
organic anion transportGO:00157111030.013
small molecule biosynthetic processGO:00442831570.013
establishment of protein localization to organelleGO:00725941720.013
cellular response to nitrogen compoundGO:19016991440.013
hematopoietic or lymphoid organ developmentGO:00485341860.013
rhythmic behaviorGO:000762220.013
actin mediated cell contractionGO:0070252120.013
response to cytokineGO:00340972320.013
cellular response to external stimulusGO:00714961110.013
cell cell junction organizationGO:0045216690.013
cell activationGO:00017752130.013
purine nucleoside monophosphate metabolic processGO:00091261860.013
immune system developmentGO:00025201950.013
regulation of protein maturationGO:19033171500.013
regulation of actin filament based processGO:00329701410.013
Fly
protein oligomerizationGO:00512591730.013
regulation of endopeptidase activityGO:00525481700.013
cell cycle phase transitionGO:00447701730.013
positive regulation of cell proliferationGO:00082843010.013
regulation of protein processingGO:00706131500.013
cytokine productionGO:00018162470.013
circadian behaviorGO:004851220.013
positive regulation of protein transportGO:00512221350.013
cell morphogenesis involved in differentiationGO:00009041440.013
mitotic cell cycle phase transitionGO:00447721620.013
circulatory system developmentGO:00723592620.013
cell projection morphogenesisGO:00488581290.013
axon cargo transportGO:000808820.012
metal ion homeostasisGO:00550651690.012
regulation of cytokine productionGO:00018172320.012
neural tube formationGO:000184130.012
innate immune responseGO:00450871780.012
atp metabolic processGO:00460341760.012
cation homeostasisGO:00550801890.012
regulation of secretionGO:00510461940.012
positive regulation of cellular component biogenesisGO:00440891580.012
Fly
reactive nitrogen species metabolic processGO:200105730.012
regulation of homeostatic processGO:00328441210.012
cell substrate adhesionGO:00315891320.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
negative regulation of cell cycleGO:00457861930.012
single organism reproductive processGO:0044702980.012
Fly
establishment of planar polarityGO:000173630.012
positive regulation of protein serine threonine kinase activityGO:00719021190.012
negative regulation of kinase activityGO:00336731060.012
purine ribonucleoside monophosphate metabolic processGO:00091671860.012
regulation of reactive oxygen species metabolic processGO:2000377410.012
ribonucleoside monophosphate metabolic processGO:00091611870.012
chromatin organizationGO:00063253510.012
regulation of transporter activityGO:0032409820.012
positive regulation of immune system processGO:00026842830.012
negative regulation of cell proliferationGO:00082852280.012
response to nitrogen compoundGO:19016981840.012
regulation of secretion by cellGO:19035301770.012
response to organic cyclic compoundGO:00140702040.012
positive regulation of proteolysisGO:00458621420.012
morphogenesis of a polarized epitheliumGO:000173830.012
hemopoiesisGO:00300971800.012
regulation of protein complex assemblyGO:00432541470.012
Fly
cellular carbohydrate metabolic processGO:0044262840.012
negative regulation of transportGO:00510511760.012
monocarboxylic acid metabolic processGO:00327871850.012
reproductive processGO:00224141060.012
Fly
glycoprotein metabolic processGO:00091001100.012
meiosis iGO:000712740.012
positive regulation of cell migrationGO:00303351720.012
chromatin modificationGO:00165682980.012
negative regulation of cellular component movementGO:00512711060.011
peptidyl tyrosine phosphorylationGO:00181081700.011
regulation of multi organism processGO:00439001570.011
response to external biotic stimulusGO:00432072610.011
nuclear migrationGO:000709710.011
rna interferenceGO:001624640.011
muscle contractionGO:0006936730.011
covalent chromatin modificationGO:00165692540.011
regulation of nucleocytoplasmic transportGO:0046822980.011
rna processingGO:00063962550.011
metencephalon developmentGO:002203720.011
negative regulation of protein maturationGO:19033181420.011
inner ear morphogenesisGO:004247240.011
cell projection assemblyGO:00300311260.011
autophagyGO:0006914880.011
response to fungusGO:000962040.011
glycerophospholipid metabolic processGO:0006650840.011
motor neuron axon guidanceGO:000804520.011
nerve developmentGO:002167540.011
cellular cation homeostasisGO:00300031630.011
asymmetric stem cell divisionGO:009872210.011
positive regulation of cell differentiationGO:00455972110.011
cerebellum developmentGO:002154920.011
protein importGO:00170381300.011
positive regulation of intracellular transportGO:00323881040.011
embryo developmentGO:00097901230.011
Fly
positive regulation of reactive oxygen species metabolic processGO:2000379240.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.011
nucleoside monophosphate metabolic processGO:00091231910.011
wound healingGO:00420601150.011
compound eye developmentGO:004874910.011
response to inorganic substanceGO:00100351270.011
regulation of sequence specific dna binding transcription factor activityGO:00510902110.011
negative regulation of organelle organizationGO:00106391260.011
positive regulation of cellular component movementGO:00512721810.011
negative regulation of protein processingGO:00109551420.011
synaptic vesicle endocytosisGO:004848820.011
response to biotic stimulusGO:00096072760.011
negative regulation of synaptic transmissionGO:005080520.011
establishment of nucleus localizationGO:004002310.011
head developmentGO:00603221080.011
somatic muscle developmentGO:000752510.011
intracellular mrna localizationGO:000829810.011
small molecule catabolic processGO:0044282920.011
dna repairGO:00062811980.011
response to radiationGO:00093141510.011
single organism nuclear importGO:19025931040.011
organelle localizationGO:0051640840.011
alcohol metabolic processGO:00060661140.011
atp catabolic processGO:00062001570.011
protein polyubiquitinationGO:00002091100.011
rab protein signal transductionGO:003248240.011
sequestering of metal ionGO:0051238240.011
response to oxidative stressGO:00069791210.011
negative regulation of protein kinase activityGO:0006469980.011
symbiosis encompassing mutualism through parasitismGO:00444031560.011
regulation of anatomical structure sizeGO:00900661010.011
Fly
cardiac muscle contractionGO:0060048340.011
lipid modificationGO:0030258840.011
neural tube closureGO:000184330.011
organic acid biosynthetic processGO:0016053970.011
axis elongationGO:000340140.011
golgi vesicle transportGO:0048193800.010
muscle system processGO:0003012810.010
negative regulation of proteolysisGO:00458611320.010
regulation of meiotic cell cycleGO:005144540.010
visual behaviorGO:000763220.010
primary neural tube formationGO:001402030.010
response to organonitrogen compoundGO:00102431560.010
positive regulation of protein catabolic processGO:0045732750.010
negative regulation of cellular catabolic processGO:0031330830.010
limbic system developmentGO:002176130.010
salivary gland morphogenesisGO:000743540.010
organelle fissionGO:00482851490.010
cellular ion homeostasisGO:00068731680.010
neuron projection developmentGO:00311751060.010
positive regulation of organelle organizationGO:00106381950.010
Fly
peptidyl tyrosine modificationGO:00182121700.010
regulation of ion transmembrane transportGO:00347651320.010
visual learningGO:000854210.010
epithelium migrationGO:00901321190.010
behaviorGO:00076101120.010
histone modificationGO:00165702510.010

SPIRE1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.024
sensory system diseaseDOID:00501552030.023
nervous system diseaseDOID:8634310.023
disease of metabolismDOID:00146672950.022
disease of cellular proliferationDOID:145661740.022
inherited metabolic disorderDOID:6552420.020
cancerDOID:1621670.019
organ system cancerDOID:00506861640.019
central nervous system diseaseDOID:3311860.019
eye and adnexa diseaseDOID:14921500.014
eye diseaseDOID:56141490.014
cardiovascular system diseaseDOID:12871060.013
myopathyDOID:4231040.013
muscular diseaseDOID:00800001140.013
muscle tissue diseaseDOID:661130.013
retinal diseaseDOID:56791180.012
connective tissue diseaseDOID:651090.012
brain diseaseDOID:936730.011