Homo sapiens

19 known processes

SHANK1

SH3 and multiple ankyrin repeat domains 1

(Aliases: synamon,SSTRIP,SPANK-1)

SHANK1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of wnt protein secretionGO:006135810.212
opioid receptor signaling pathwayGO:003800340.204
somatostatin receptor signaling pathwayGO:003816910.130
cellular amino acid metabolic processGO:00065201160.127
adenylate cyclase inhibiting opioid receptor signaling pathwayGO:003163510.126
somatostatin signaling pathwayGO:003817010.122
nervous system developmentGO:00073992930.114
Mouse Rat
regulation of cellular amino acid metabolic processGO:000652160.090
positive regulation of transportGO:00510503360.087
ion transmembrane transportGO:00342203380.082
Mouse
g protein coupled receptor signaling pathwayGO:00071862070.080
cation transmembrane transportGO:00986552380.076
positive regulation of large conductance calcium activated potassium channel activityGO:190260820.075
regulation of protein localizationGO:00328802960.073
transmembrane transportGO:00550853990.067
Mouse
positive regulation of cellular amine metabolic processGO:003324070.066
regulation of large conductance calcium activated potassium channel activityGO:190260620.066
amine metabolic processGO:0009308440.064
protein localization to organelleGO:00333652800.063
positive regulation of cellular amino acid metabolic processGO:004576430.063
cellular ketone metabolic processGO:0042180800.062
positive regulation of glucocorticoid secretionGO:200085140.062
peripheral nervous system developmentGO:000742220.060
cytoplasmic transportGO:00164823790.060
positive regulation of cellular component organizationGO:00511303760.059
Rat
cellular amine metabolic processGO:0044106410.054
response to oxygen containing compoundGO:19017003690.052
negative regulation of cellular component organizationGO:00511292350.051
Mouse
reactive nitrogen species metabolic processGO:200105730.051
cellular macromolecule catabolic processGO:00442653800.051
positive regulation of reactive oxygen species biosynthetic processGO:190342820.051
hindbrain developmentGO:003090230.051
regulation of cellular amine metabolic processGO:0033238110.051
negative regulation of multicellular organismal processGO:00512413170.049
post embryonic developmentGO:000979120.048
regulation of ion transmembrane transporter activityGO:0032412720.048
Mouse
lipid metabolic processGO:00066293810.047
regulation of transporter activityGO:0032409820.047
Mouse
regulation of establishment of protein localizationGO:00702012420.046
reactive oxygen species metabolic processGO:0072593750.046
regulation of cellular component biogenesisGO:00440872810.043
Mouse
regulation of transmembrane transporter activityGO:0022898740.043
Mouse
central nervous system developmentGO:00074171230.042
behavioral response to ethanolGO:004814920.042
regulation of protein transportGO:00512232130.041
protein catabolic processGO:00301633250.041
small gtpase mediated signal transductionGO:0007264780.040
cellular response to oxygen containing compoundGO:19017012760.040
organonitrogen compound biosynthetic processGO:19015662000.039
response to biotic stimulusGO:00096072760.039
chemical homeostasisGO:00488783060.038
negative regulation of cytosolic calcium ion concentrationGO:005148110.037
regulation of cell cycleGO:00517263930.037
vesicle mediated transportGO:00161923710.036
regulation of reactive oxygen species metabolic processGO:2000377410.036
positive regulation of phosphorylationGO:00423273940.036
nuclear transportGO:00511691790.035
immune responseGO:00069553070.034
regulation of reactive oxygen species biosynthetic processGO:190342630.034
regulation of cellular ketone metabolic processGO:0010565500.034
cell developmentGO:00484683280.033
Mouse Rat
metencephalon developmentGO:002203720.033
cellular response to endogenous stimulusGO:00714953360.032
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188430.032
response to abiotic stimulusGO:00096283360.031
small molecule catabolic processGO:0044282920.031
segmentationGO:003528240.031
cellular macromolecular complex assemblyGO:00346223240.031
memoryGO:000761330.031
Mouse
regulation of cell cycle processGO:00105642660.030
defense responseGO:00069523150.030
regulation of protein complex assemblyGO:00432541470.030
positive regulation of developmental processGO:00510943140.030
Rat
response to organic cyclic compoundGO:00140702040.030
female gamete generationGO:000729220.030
cation transportGO:00068123310.030
nucleocytoplasmic transportGO:00069131760.030
cellular response to dna damage stimulusGO:00069743790.030
purine containing compound catabolic processGO:00725234110.029
cellular protein catabolic processGO:00442572610.029
regulation of ion transportGO:00432691890.029
Mouse
nucleotide catabolic processGO:00091664080.028
neuron projection developmentGO:00311751060.028
Mouse Rat
nucleoside triphosphate metabolic processGO:00091414220.028
locomotory behaviorGO:000762610.028
positive regulation of secretion by cellGO:19035321080.028
head developmentGO:00603221080.028
nucleoside phosphate catabolic processGO:19012924120.028
negative regulation of reactive oxygen species metabolic processGO:2000378110.028
organophosphate catabolic processGO:00464344300.028
regulation of secretion by cellGO:19035301770.028
intracellular protein transportGO:00068862700.027
regulation of proteolysisGO:00301622930.027
cell projection organizationGO:00300302520.027
Mouse Rat
negative regulation of catalytic activityGO:00430863350.027
cell cell signalingGO:00072671550.027
Mouse
single organism cellular localizationGO:19025803320.026
multicellular organismal agingGO:001025930.026
negative regulation of protein metabolic processGO:00512483910.026
negative regulation of transportGO:00510511760.026
secretion by cellGO:00329402260.026
establishment of protein localization to organelleGO:00725941720.026
secretionGO:00469032540.026
ribonucleotide catabolic processGO:00092614050.026
cellular response to toxic substanceGO:009723740.026
negative regulation of reactive oxygen species biosynthetic processGO:190342710.025
cellular response to hormone stimulusGO:00328701250.025
purine ribonucleoside triphosphate metabolic processGO:00092054110.025
positive regulation of reactive oxygen species metabolic processGO:2000379240.025
chromatin organizationGO:00063253510.025
cell morphogenesisGO:00009022960.025
Mouse
system processGO:00030083490.025
ras protein signal transductionGO:0007265730.024
protein secretionGO:0009306980.024
protein targeting to nucleusGO:00447441040.024
positive regulation of cell deathGO:00109422630.024
determination of adult lifespanGO:000834020.024
proteasomal protein catabolic processGO:00104981760.024
cell divisionGO:00513011680.024
chromatin modificationGO:00165682980.024
cellular component morphogenesisGO:00329893140.024
Mouse
guanosine containing compound catabolic processGO:19010692390.024
mitotic cell cycleGO:00002783260.024
positive regulation of protein phosphorylationGO:00019343130.024
regulation of cell projection organizationGO:00313441070.024
Rat
oogenesisGO:004847720.023
inorganic cation transmembrane transportGO:00986621940.023
nucleoside catabolic processGO:00091644080.023
positive regulation of hydrolase activityGO:00513453310.023
anion transportGO:00068201610.023
histone modificationGO:00165702510.023
positive regulation of catabolic processGO:00098963100.023
defense response to other organismGO:00985421290.023
peptidyl serine modificationGO:00182091060.023
lipid localizationGO:00108761060.023
protein localization to nucleusGO:00345041360.023
response to virusGO:00096151260.022
protein targetingGO:00066051870.022
negative regulation of cellular protein metabolic processGO:00322693530.022
regulation of cell developmentGO:00602841610.021
Rat
nuclear importGO:00511701060.021
purine ribonucleoside catabolic processGO:00461303980.021
motor neuron axon guidanceGO:000804520.021
nucleoside triphosphate catabolic processGO:00091433940.021
regulation of anatomical structure morphogenesisGO:00226032860.021
reactive oxygen species biosynthetic processGO:190340940.021
purine nucleotide catabolic processGO:00061954050.021
response to external biotic stimulusGO:00432072610.021
regulation of protein secretionGO:0050708860.021
single organism nuclear importGO:19025931040.021
regulation of cell motilityGO:20001452990.021
inorganic ion transmembrane transportGO:00986602310.021
negative regulation of cellular amino acid metabolic processGO:004576320.021
purine ribonucleoside metabolic processGO:00461284370.020
associative learningGO:000830610.020
Mouse
cellular protein complex assemblyGO:00436231880.020
defense response to virusGO:0051607710.020
biological adhesionGO:00226103310.020
ribonucleoside triphosphate metabolic processGO:00091994120.020
cerebellum developmentGO:002154920.020
negative regulation of hydrolase activityGO:00513461820.020
proteolysis involved in cellular protein catabolic processGO:00516032440.020
regulation of wnt protein secretionGO:006135610.019
regulation of synaptic plasticityGO:004816730.019
regulation of locomotionGO:00400123290.019
negative regulation of camp mediated signalingGO:004395140.019
regulation of cell divisionGO:00513021160.019
negative regulation of organelle organizationGO:00106391260.019
Mouse
protein importGO:00170381300.019
regulation of nucleotide metabolic processGO:00061402690.019
oxidation reduction processGO:00551143960.019
wnt protein secretionGO:006135510.019
muscle contractionGO:0006936730.019
regulation of cellular response to stressGO:00801352440.019
response to other organismGO:00517072610.018
adult locomotory behaviorGO:000834410.018
purine nucleoside triphosphate metabolic processGO:00091444120.018
covalent chromatin modificationGO:00165692540.018
protein import into nucleusGO:00066061040.018
neuromuscular junction developmentGO:000752830.018
regulation of cytoskeleton organizationGO:00514931770.018
Mouse
divalent inorganic cation homeostasisGO:00725071360.018
purine nucleoside triphosphate catabolic processGO:00091463920.018
regulation of intracellular transportGO:00323861950.018
second messenger mediated signalingGO:0019932780.018
fatty acid metabolic processGO:00066311150.018
response to oxygen levelsGO:00704821000.018
blastoderm segmentationGO:000735020.018
positive regulation of secretionGO:00510471160.018
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.018
purine ribonucleoside triphosphate catabolic processGO:00092073910.018
negative regulation of intracellular signal transductionGO:19025321830.018
ribonucleoside triphosphate catabolic processGO:00092033910.018
regulation of vesicle mediated transportGO:00606271300.018
regulation of protein catabolic processGO:00421761550.018
cellular calcium ion homeostasisGO:00068741170.018
guanosine containing compound metabolic processGO:19010682440.017
cellular homeostasisGO:00197251960.017
generation of neuronsGO:00486991520.017
Mouse Rat
cortisol secretionGO:004340040.017
dephosphorylationGO:00163112090.017
cellular response to nitrogen compoundGO:19016991440.017
cell projection assemblyGO:00300311260.017
single organism membrane organizationGO:00448022680.017
cell projection morphogenesisGO:00488581290.017
Mouse
response to hormoneGO:00097251750.017
negative regulation of phosphate metabolic processGO:00459362670.017
negative regulation of phosphorus metabolic processGO:00105632670.017
protein processingGO:00164852260.017
carbohydrate derivative biosynthetic processGO:19011372070.016
regulation of transmembrane transportGO:00347621390.016
Mouse
regulation of cellular component movementGO:00512703340.016
regulation of protein processingGO:00706131500.016
regulation of cell differentiationGO:00455953930.016
Rat
regulation of secretionGO:00510461940.016
cellular ion homeostasisGO:00068731680.016
regulation of cell morphogenesisGO:00226041530.016
regulation of neuron differentiationGO:0045664700.016
Rat
regulation of protein kinase activityGO:00458592890.016
positive regulation of gtp catabolic processGO:00331261660.016
positive regulation of monocyte chemotactic protein 1 productionGO:007163930.016
positive regulation of nucleoside metabolic processGO:00459791860.015
negative regulation of cellular amine metabolic processGO:003323930.015
negative regulation of developmental processGO:00510932470.015
cellular cation homeostasisGO:00300031630.015
regulation of cytoplasmic transportGO:19036491490.015
protein maturationGO:00516042330.015
metal ion transportGO:00300012720.015
protein modification by small protein conjugationGO:00324463420.015
cellular lipid metabolic processGO:00442553030.015
glycosyl compound catabolic processGO:19016584130.015
regulation of gtp catabolic processGO:00331241800.015
regulation of cytokine productionGO:00018172320.015
ribonucleoside catabolic processGO:00424544060.015
regulation of cation channel activityGO:2001257330.015
cyclic nucleotide mediated signalingGO:0019935260.015
negative regulation of protein modification processGO:00314002000.015
regulation of cell adhesionGO:00301551660.015
calcium ion homeostasisGO:00550741220.015
positive regulation of cellular component biogenesisGO:00440891580.015
positive regulation of cell cycle processGO:00900681060.015
cellular response to glucocorticoid stimulusGO:007138540.015
organophosphate biosynthetic processGO:00904071630.015
response to decreased oxygen levelsGO:0036293960.015
peptidyl serine phosphorylationGO:00181051010.015
positive regulation of apoptotic processGO:00430652460.014
protein ubiquitinationGO:00165673140.014
response to nitrogen compoundGO:19016981840.014
regulation of purine nucleotide metabolic processGO:19005422640.014
spermatid differentiationGO:004851540.014
neuropeptide signaling pathwayGO:0007218190.014
positive regulation of cell differentiationGO:00455972110.014
Rat
positive regulation of cellular catabolic processGO:00313312840.014
ion homeostasisGO:00508012300.014
positive regulation of protein transportGO:00512221350.014
regulation of cortisol secretionGO:005146240.014
regulation of transferase activityGO:00513383550.014
cellular chemical homeostasisGO:00550821800.014
protein oligomerizationGO:00512591730.014
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187430.014
regulation of growthGO:00400081650.014
positive regulation of programmed cell deathGO:00430682490.014
glial cell migrationGO:000834740.014
immune effector processGO:00022521590.014
cardiovascular system developmentGO:00723582620.014
response to hypoxiaGO:0001666960.014
monocarboxylic acid metabolic processGO:00327871850.014
positive regulation of cytosolic calcium ion concentrationGO:0007204820.013
modification dependent macromolecule catabolic processGO:00436322120.013
actin cytoskeleton organizationGO:00300362070.013
Mouse
modification dependent protein catabolic processGO:00199412090.013
cellular response to hypoxiaGO:0071456510.013
cell adhesionGO:00071553250.013
purine nucleoside catabolic processGO:00061523980.013
regulation of purine nucleotide catabolic processGO:00331212050.013
circadian behaviorGO:004851220.013
glucocorticoid secretionGO:003593340.013
negative regulation of protein transportGO:0051224750.013
epithelial cell differentiationGO:00308551410.013
positive regulation of purine nucleotide metabolic processGO:19005442270.013
positive regulation of cell proliferationGO:00082843010.013
regulation of kinase activityGO:00435493140.013
cellular response to organonitrogen compoundGO:00714171240.013
microtubule based processGO:00070172100.013
regulation of nucleoside metabolic processGO:00091182090.013
spermatid developmentGO:000728640.013
lipid catabolic processGO:0016042840.013
positive regulation of cell developmentGO:0010720920.013
Rat
regulation of sequence specific dna binding transcription factor activityGO:00510902110.013
cytokinesisGO:0000910960.013
gtp catabolic processGO:00061842370.013
mitotic cell cycle processGO:19030472860.012
compound eye developmentGO:004874910.012
cellular response to oxygen levelsGO:0071453550.012
metal ion homeostasisGO:00550651690.012
hematopoietic or lymphoid organ developmentGO:00485341860.012
anatomical structure formation involved in morphogenesisGO:00486462840.012
maintenance of locationGO:00512351120.012
negative regulation of immune system processGO:00026831360.012
cellular response to organic cyclic compoundGO:00714071270.012
regulation of multi organism processGO:00439001570.012
regulation of meiotic cell cycleGO:005144540.012
response to cytokineGO:00340972320.012
regulation of ras gtpase activityGO:00323181280.012
mapk cascadeGO:00001652880.012
negative regulation of phosphorylationGO:00423261740.012
regulation of response to external stimulusGO:00321012220.012
negative regulation of synaptic transmissionGO:005080520.012
organic hydroxy compound transportGO:0015850630.012
rna processingGO:00063962550.012
response to oxidative stressGO:00069791210.012
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.012
negative regulation of protein complex assemblyGO:0031333430.012
peptidyl lysine modificationGO:00182051440.012
regulation of protein maturationGO:19033171500.012
positive regulation of nucleotide metabolic processGO:00459812300.012
i kappab kinase nf kappab signalingGO:00072491660.012
nerve developmentGO:002167540.012
regenerationGO:003109940.012
nitrogen compound transportGO:00717051910.012
cytokine productionGO:00018162470.012
ribose phosphate biosynthetic processGO:0046390820.011
negative regulation of protein maturationGO:19033181420.011
regulation of gtpase activityGO:00430871800.011
rho protein signal transductionGO:0007266260.011
response to lipidGO:00339932060.011
single organism cell adhesionGO:00986021790.011
lipid transportGO:0006869900.011
response to nutrient levelsGO:0031667810.011
ubiquitin dependent protein catabolic processGO:00065112060.011
response to organonitrogen compoundGO:00102431560.011
peptidyl tyrosine modificationGO:00182121700.011
response to extracellular stimulusGO:0009991850.011
posttranscriptional regulation of gene expressionGO:00106082130.011
neurological system processGO:00508771630.011
organ formationGO:004864530.011
protein polymerizationGO:0051258710.011
positive regulation of locomotionGO:00400171860.011
membrane organizationGO:00610242920.011
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.011
positive regulation of proteolysisGO:00458621420.011
positive regulation of peptidyl serine phosphorylationGO:0033138420.011
regulation of apoptotic signaling pathwayGO:20012331750.011
organic acid catabolic processGO:0016054710.011
hormone transportGO:0009914680.011
osteoblast differentiationGO:0001649920.011
negative regulation of cell cycleGO:00457861930.011
response to axon injuryGO:004867810.011
methylationGO:00322591060.011
negative regulation of cell differentiationGO:00455961710.011
ameboidal type cell migrationGO:00016671350.011
regulation of cellular protein catabolic processGO:1903362960.011
positive regulation of organelle organizationGO:00106381950.011
small molecule biosynthetic processGO:00442831570.011
positive regulation of ion transmembrane transporter activityGO:0032414290.011
negative regulation of proteolysisGO:00458611320.011
purine nucleotide biosynthetic processGO:0006164840.011
regulation of hormone levelsGO:00108171250.011
protein localization to membraneGO:00726571600.011
apoptotic signaling pathwayGO:00971902680.011
purine containing compound biosynthetic processGO:0072522880.011
gtp metabolic processGO:00460392390.011
positive regulation of intracellular transportGO:00323881040.011
regulation of lipid transportGO:0032368440.010
ribonucleotide biosynthetic processGO:0009260810.010
regulation of proteasomal protein catabolic processGO:0061136870.010
neuron developmentGO:00486661130.010
Mouse Rat
protein autophosphorylationGO:00467771230.010
signal transduction by phosphorylationGO:00230142970.010
regulation of intracellular protein transportGO:00331571230.010
negative regulation of secretion by cellGO:1903531520.010
positive regulation of gtpase activityGO:00435471660.010
neurotransmitter secretionGO:000726940.010
negative regulation of secretionGO:0051048580.010
negative regulation of protein processingGO:00109551420.010
regulation of response to dna damage stimulusGO:2001020940.010
regulation of protein serine threonine kinase activityGO:00719001790.010
regulation of peptidase activityGO:00525471800.010
endomembrane system organizationGO:00102561960.010
dna repairGO:00062811980.010
hemopoiesisGO:00300971800.010
monovalent inorganic cation transportGO:00156721280.010
positive regulation of cell divisionGO:0051781590.010
negative regulation of catabolic processGO:00098951040.010
carboxylic acid catabolic processGO:0046395710.010
regulation of small gtpase mediated signal transductionGO:00510561560.010
positive regulation of kinase activityGO:00336742040.010
oocyte differentiationGO:000999420.010
actin filament based processGO:00300292240.010
Mouse
anterior posterior axis specificationGO:000994820.010
negative regulation of protein phosphorylationGO:00019331400.010

SHANK1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:00501552030.022
nervous system diseaseDOID:8634310.022
eye and adnexa diseaseDOID:14921500.013
eye diseaseDOID:56141490.013
disease of metabolismDOID:00146672950.011
disease of cellular proliferationDOID:145661740.010