Homo sapiens

0 known processes

ISM2

isthmin 2 homolog (zebrafish)

(Aliases: DKFZp686E0215,MGC119416,FLJ32147,THSD3,TAIL1)

ISM2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.077
cellular amino acid metabolic processGO:00065201160.073
regulation of cellular ketone metabolic processGO:0010565500.067
amine metabolic processGO:0009308440.064
regulation of cellular amino acid metabolic processGO:000652160.063
cellular amine metabolic processGO:0044106410.060
regulation of cellular amine metabolic processGO:0033238110.059
circulatory system developmentGO:00723592620.056
cellular ketone metabolic processGO:0042180800.053
segmentationGO:003528240.053
positive regulation of cellular amino acid metabolic processGO:004576430.053
positive regulation of cellular amine metabolic processGO:003324070.050
epithelium developmentGO:00604292270.047
organ morphogenesisGO:00098871470.045
positive regulation of phosphorylationGO:00423273940.042
transmembrane transportGO:00550853990.040
cardiovascular system developmentGO:00723582620.039
secretion by cellGO:00329402260.039
positive regulation of cell proliferationGO:00082843010.039
cell fate determinationGO:000170930.039
cytoplasmic transportGO:00164823790.039
regulation of hormone levelsGO:00108171250.037
regulation of protein localizationGO:00328802960.037
regulation of cellular component movementGO:00512703340.036
ras protein signal transductionGO:0007265730.036
single organism cellular localizationGO:19025803320.036
anatomical structure formation involved in morphogenesisGO:00486462840.035
multicellular organismal agingGO:001025930.035
epidermis morphogenesisGO:004873030.034
hair follicle morphogenesisGO:003106920.033
chemical homeostasisGO:00488783060.033
secretionGO:00469032540.033
small gtpase mediated signal transductionGO:0007264780.033
determination of adult lifespanGO:000834020.032
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.032
regulation of protein transportGO:00512232130.032
purine ribonucleoside metabolic processGO:00461284370.032
system processGO:00030083490.032
regulation of anatomical structure morphogenesisGO:00226032860.032
embryonic forelimb morphogenesisGO:003511540.031
negative regulation of cell deathGO:00605483450.031
negative regulation of developmental processGO:00510932470.031
immune responseGO:00069553070.031
regulation of cell differentiationGO:00455953930.030
cell cell signalingGO:00072671550.030
positive regulation of cellular component organizationGO:00511303760.030
negative regulation of catalytic activityGO:00430863350.029
biological adhesionGO:00226103310.029
nervous system developmentGO:00073992930.029
cell developmentGO:00484683280.029
negative regulation of programmed cell deathGO:00430693210.029
cell adhesionGO:00071553250.029
defense responseGO:00069523150.029
hindbrain developmentGO:003090230.029
epithelial cell differentiationGO:00308551410.028
organ formationGO:004864530.028
ribonucleoside triphosphate catabolic processGO:00092033910.028
vesicle mediated transportGO:00161923710.028
purine nucleoside triphosphate catabolic processGO:00091463920.028
locomotory behaviorGO:000762610.028
regenerationGO:003109940.027
regulation of cell motilityGO:20001452990.027
negative regulation of apoptotic processGO:00430663160.027
positive regulation of protein phosphorylationGO:00019343130.027
cation transportGO:00068123310.027
regulation of transferase activityGO:00513383550.027
single organism membrane organizationGO:00448022680.027
nucleoside catabolic processGO:00091644080.027
female gamete generationGO:000729220.026
purine ribonucleoside triphosphate catabolic processGO:00092073910.026
cation transmembrane transportGO:00986552380.026
ribonucleotide catabolic processGO:00092614050.026
glycosyl compound catabolic processGO:19016584130.026
actin filament based processGO:00300292240.026
purine nucleotide catabolic processGO:00061954050.026
regulation of locomotionGO:00400123290.026
regulation of establishment of protein localizationGO:00702012420.026
regulation of cell cycleGO:00517263930.025
negative regulation of protein metabolic processGO:00512483910.025
positive regulation of transportGO:00510503360.025
positive regulation of developmental processGO:00510943140.025
nucleoside phosphate catabolic processGO:19012924120.025
morphogenesis of embryonic epitheliumGO:001633140.025
nucleoside triphosphate metabolic processGO:00091414220.025
purine nucleoside triphosphate metabolic processGO:00091444120.025
cellular macromolecule catabolic processGO:00442653800.025
purine containing compound catabolic processGO:00725234110.025
regulation of cellular response to stressGO:00801352440.025
negative regulation of cell proliferationGO:00082852280.025
protein localization to organelleGO:00333652800.025
negative regulation of phosphate metabolic processGO:00459362670.025
purine ribonucleoside triphosphate metabolic processGO:00092054110.025
purine ribonucleoside catabolic processGO:00461303980.025
ribonucleoside catabolic processGO:00424544060.025
intracellular protein transportGO:00068862700.024
enzyme linked receptor protein signaling pathwayGO:00071673030.024
cellular component morphogenesisGO:00329893140.024
nitrogen compound transportGO:00717051910.024
negative regulation of cellular protein metabolic processGO:00322693530.024
purine nucleoside catabolic processGO:00061523980.024
negative regulation of phosphorus metabolic processGO:00105632670.024
regulation of cell migrationGO:00303342890.024
nucleotide catabolic processGO:00091664080.024
negative regulation of multicellular organismal processGO:00512413170.023
oogenesisGO:004847720.023
response to abiotic stimulusGO:00096283360.023
ion transmembrane transportGO:00342203380.023
blastoderm segmentationGO:000735020.023
positive regulation of cell differentiationGO:00455972110.023
mitotic cell cycleGO:00002783260.023
positive regulation of cellular catabolic processGO:00313312840.023
mapk cascadeGO:00001652880.023
ribonucleoside triphosphate metabolic processGO:00091994120.023
purine ribonucleotide catabolic processGO:00091544040.023
cardiac cell fate determinationGO:006091330.023
positive regulation of catabolic processGO:00098963100.023
cellular response to endogenous stimulusGO:00714953360.022
nucleoside triphosphate catabolic processGO:00091433940.022
organophosphate catabolic processGO:00464344300.022
regulation of kinase activityGO:00435493140.022
negative regulation of cell differentiationGO:00455961710.022
positive regulation of hydrolase activityGO:00513453310.022
protein catabolic processGO:00301633250.022
anterior posterior axis specificationGO:000994820.022
cellular homeostasisGO:00197251960.022
positive regulation of nucleotide metabolic processGO:00459812300.022
protein maturationGO:00516042330.021
protein localization to membraneGO:00726571600.021
cellular response to dna damage stimulusGO:00069743790.021
response to woundingGO:00096111680.021
regulation of mapk cascadeGO:00434082620.021
vasculature developmentGO:00019441810.021
regulation of protein kinase activityGO:00458592890.021
regulation of secretionGO:00510461940.021
regulation of cytokine productionGO:00018172320.021
growthGO:00400072020.021
protein targetingGO:00066051870.021
carbohydrate derivative biosynthetic processGO:19011372070.021
cell morphogenesisGO:00009022960.021
lipid metabolic processGO:00066293810.021
motor neuron axon guidanceGO:000804520.020
inorganic cation transmembrane transportGO:00986621940.020
peripheral nervous system developmentGO:000742220.020
neuromuscular junction developmentGO:000752830.020
response to oxygen containing compoundGO:19017003690.020
positive regulation of immune system processGO:00026842830.020
regulation of proteolysisGO:00301622930.020
signal transduction by phosphorylationGO:00230142970.020
organonitrogen compound biosynthetic processGO:19015662000.020
cellular protein catabolic processGO:00442572610.020
rho protein signal transductionGO:0007266260.020
ion homeostasisGO:00508012300.020
regulation of purine nucleotide metabolic processGO:19005422640.019
guanosine containing compound catabolic processGO:19010692390.019
membrane organizationGO:00610242920.019
negative regulation of locomotionGO:00400131180.019
inner ear morphogenesisGO:004247240.019
inorganic ion transmembrane transportGO:00986602310.019
cell projection organizationGO:00300302520.019
tissue morphogenesisGO:0048729960.019
cation homeostasisGO:00550801890.019
endomembrane system organizationGO:00102561960.019
gtp metabolic processGO:00460392390.019
regulation of nucleotide metabolic processGO:00061402690.018
guanosine containing compound metabolic processGO:19010682440.018
regulation of cell cycle processGO:00105642660.018
neurogenesisGO:00220081690.018
reactive oxygen species metabolic processGO:0072593750.018
regulation of immune responseGO:00507762010.018
positive regulation of purine nucleotide metabolic processGO:19005442270.018
forelimb morphogenesisGO:003513640.018
cell growthGO:00160491600.018
adult locomotory behaviorGO:000834410.018
regulation of cellular component biogenesisGO:00440872810.018
positive regulation of apoptotic processGO:00430652460.018
nuclear transportGO:00511691790.018
nucleocytoplasmic transportGO:00069131760.018
positive regulation of transferase activityGO:00513472270.017
wnt signaling pathwayGO:00160551560.017
mitotic cell cycle processGO:19030472860.017
innate immune responseGO:00450871780.017
positive regulation of protein transportGO:00512221350.017
gtp catabolic processGO:00061842370.017
metencephalon developmentGO:002203720.017
regulation of wnt signaling pathwayGO:00301111230.017
cytokine productionGO:00018162470.017
regulation of response to external stimulusGO:00321012220.017
protein localization to nucleusGO:00345041360.017
cellular ion homeostasisGO:00068731680.017
apoptotic signaling pathwayGO:00971902680.017
regulation of sequence specific dna binding transcription factor activityGO:00510902110.017
epidermis developmentGO:0008544590.017
actin cytoskeleton organizationGO:00300362070.017
cellular lipid metabolic processGO:00442553030.017
negative regulation of cellular component organizationGO:00511292350.017
blood vessel developmentGO:00015681720.017
specification of organ identityGO:001009230.016
central nervous system developmentGO:00074171230.016
protein oligomerizationGO:00512591730.016
compound eye developmentGO:004874910.016
photoreceptor cell differentiationGO:004653020.016
cellular macromolecular complex assemblyGO:00346223240.016
positive regulation of purine nucleotide catabolic processGO:00331231850.016
skin developmentGO:0043588760.016
proteolysis involved in cellular protein catabolic processGO:00516032440.016
positive regulation of programmed cell deathGO:00430682490.016
positive regulation of cytokine productionGO:00018191670.016
neurological system processGO:00508771630.016
heart formationGO:006091420.016
metal ion homeostasisGO:00550651690.016
regulation of growthGO:00400081650.016
forebrain regionalizationGO:002187130.016
dephosphorylationGO:00163112090.016
establishment of protein localization to organelleGO:00725941720.016
regulation of cytoskeleton organizationGO:00514931770.016
regulation of cell adhesionGO:00301551660.016
posttranscriptional regulation of gene expressionGO:00106082130.016
positive regulation of gtpase activityGO:00435471660.016
spermatid differentiationGO:004851540.015
embryonic epithelial tube formationGO:000183840.015
negative regulation of intracellular signal transductionGO:19025321830.015
neuron fate commitmentGO:004866320.015
head developmentGO:00603221080.015
regulation of gtpase activityGO:00430871800.015
response to external biotic stimulusGO:00432072610.015
regulation of mitotic cell cycleGO:00073461890.015
positive regulation of gtp catabolic processGO:00331261660.015
regulation of reactive oxygen species metabolic processGO:2000377410.015
heart developmentGO:0007507950.015
regulation of neural precursor cell proliferationGO:200017740.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.015
negative regulation of transportGO:00510511760.015
somitogenesisGO:000175620.015
regulation of small gtpase mediated signal transductionGO:00510561560.015
regulation of intracellular transportGO:00323861950.015
negative regulation of protein modification processGO:00314002000.015
establishment of protein localization to membraneGO:00901501210.015
divalent inorganic cation homeostasisGO:00725071360.015
protein modification by small protein conjugationGO:00324463420.015
cellular cation homeostasisGO:00300031630.015
canonical wnt signaling pathwayGO:00600701160.015
cellular metal ion homeostasisGO:00068751460.015
negative regulation of growthGO:0045926970.015
positive regulation of cell deathGO:00109422630.015
microtubule based processGO:00070172100.015
positive regulation of cell motilityGO:20001471770.015
regulation of secretion by cellGO:19035301770.015
cellular response to growth factor stimulusGO:00713631970.015
negative regulation of hydrolase activityGO:00513461820.015
regulation of purine nucleotide catabolic processGO:00331212050.014
mesonephric duct developmentGO:007217730.014
positive regulation of kinase activityGO:00336742040.014
plasma membrane organizationGO:00070091150.014
cellular divalent inorganic cation homeostasisGO:00725031280.014
positive regulation of tooth mineralizationGO:007017220.014
multi organism cellular processGO:00447641560.014
positive regulation of organelle organizationGO:00106381950.014
negative regulation of cellular amine metabolic processGO:003323930.014
positive regulation of nucleoside metabolic processGO:00459791860.014
negative regulation of cellular amino acid metabolic processGO:004576320.014
memoryGO:000761330.014
embryonic morphogenesisGO:0048598850.014
regulation of ras protein signal transductionGO:00465781550.014
regulation of cytoplasmic transportGO:19036491490.014
cell activationGO:00017752130.014
protein ubiquitinationGO:00165673140.014
metal ion transportGO:00300012720.014
organic hydroxy compound metabolic processGO:19016151470.014
response to biotic stimulusGO:00096072760.014
response to growth factorGO:00708482050.014
anterior posterior axis specification embryoGO:000859520.014
stem cell differentiationGO:0048863930.014
reactive oxygen species biosynthetic processGO:190340940.014
negative regulation of phosphorylationGO:00423261740.014
regulation of ras gtpase activityGO:00323181280.014
positive regulation of nucleotide catabolic processGO:00308131850.014
sex determinationGO:000753030.014
modification dependent protein catabolic processGO:00199412090.014
single organism cell adhesionGO:00986021790.014
response to other organismGO:00517072610.014
peptidyl tyrosine modificationGO:00182121700.014
epithelial cell proliferationGO:00506731280.014
positive regulation of protein kinase activityGO:00458601900.014
matingGO:000761810.014
generation of neuronsGO:00486991520.014
muscle structure developmentGO:0061061980.014
embryo developmentGO:00097901230.014
immune effector processGO:00022521590.014
single organismal cell cell adhesionGO:00163371480.014
regulation of endopeptidase activityGO:00525481700.014
reactive nitrogen species metabolic processGO:200105730.013
thymus developmentGO:004853830.013
regulation of nucleoside metabolic processGO:00091182090.013
regulation of gtp catabolic processGO:00331241800.013
oocyte differentiationGO:000999420.013
regulation of protein secretionGO:0050708860.013
positive regulation of cellular component movementGO:00512721810.013
modification dependent macromolecule catabolic processGO:00436322120.013
positive regulation of epithelial cell proliferation involved in wound healingGO:006005430.013
protein processingGO:00164852260.013
cardiac muscle cell contractionGO:008600340.013
spermatid developmentGO:000728640.013
neuron differentiationGO:00301821380.013
cell part morphogenesisGO:00329901370.013
cellular protein complex assemblyGO:00436231880.013
nerve developmentGO:002167540.013
regulation of nucleotide catabolic processGO:00308112050.013
tripartite regional subdivisionGO:000735120.013
cellular chemical homeostasisGO:00550821800.013
response to hormoneGO:00097251750.013
cell substrate adhesionGO:00315891320.013
oocyte developmentGO:004859910.013
cellular response to oxygen containing compoundGO:19017012760.013
protein importGO:00170381300.013
response to fungusGO:000962040.013
regulation of peptidase activityGO:00525471800.013
actin mediated cell contractionGO:0070252120.013
ubiquitin dependent protein catabolic processGO:00065112060.013
regulation of reactive oxygen species biosynthetic processGO:190342630.013
positive regulation of ras gtpase activityGO:00323201170.013
syncytium formation by plasma membrane fusionGO:000076820.013
cranial nerve developmentGO:002154540.013
regulation of multi organism processGO:00439001570.013
positive regulation of cell migrationGO:00303351720.013
maintenance of locationGO:00512351120.013
spinal cord developmentGO:002151040.013
axis elongationGO:000340140.013
positive regulation of secretion by cellGO:19035321080.013
oxidation reduction processGO:00551143960.013
positive regulation of immune responseGO:00507781590.013
hormone transportGO:0009914680.012
post embryonic organ developmentGO:004856910.012
regulation of actin filament based processGO:00329701410.012
negative regulation of cell cycleGO:00457861930.012
taxisGO:00423301570.012
proteasomal protein catabolic processGO:00104981760.012
epithelium migrationGO:00901321190.012
regulation of protein processingGO:00706131500.012
wound healingGO:00420601150.012
cerebellum developmentGO:002154920.012
rna processingGO:00063962550.012
hormone secretionGO:0046879650.012
lipid biosynthetic processGO:00086101770.012
regulation of synaptic plasticityGO:004816730.012
negative regulation of cell migrationGO:00303361020.012
tissue migrationGO:00901301190.012
positive regulation of mapk cascadeGO:00434101900.012
calcium ion homeostasisGO:00550741220.012
rhythmic behaviorGO:000762220.012
epithelial cell migrationGO:00106311190.012
viral processGO:00160321460.012
symbiosis encompassing mutualism through parasitismGO:00444031560.012
angiogenesisGO:00015251470.012
tissue regenerationGO:004224630.012
regulation of canonical wnt signaling pathwayGO:0060828880.012
protein localization to plasma membraneGO:0072659930.012
ameboidal type cell migrationGO:00016671350.012
organelle assemblyGO:00709251760.012
negative regulation of protein maturationGO:19033181420.012
regulation of protein catabolic processGO:00421761550.012
limbic system developmentGO:002176130.012
blood vessel morphogenesisGO:00485141620.012
regulation of protein maturationGO:19033171500.012
regulation of homeostatic processGO:00328441210.012
regulation of apoptotic signaling pathwayGO:20012331750.012
cell type specific apoptotic processGO:00972851250.012
regulation of protein serine threonine kinase activityGO:00719001790.012
response to organic cyclic compoundGO:00140702040.012
cellular response to cytokine stimulusGO:00713451810.012
positive regulation of cellular component biogenesisGO:00440891580.012
regulation of vasculature developmentGO:1901342970.012
negative regulation of cellular component movementGO:00512711060.012
cell cycle phase transitionGO:00447701730.012
negative regulation of protein phosphorylationGO:00019331400.012
response to cytokineGO:00340972320.012
chromatin organizationGO:00063253510.012
neurotransmitter secretionGO:000726940.012
actin filament based movementGO:0030048170.012
positive regulation of secretionGO:00510471160.012
cell divisionGO:00513011680.012
response to virusGO:00096151260.012
non canonical wnt signaling pathway via mapk cascadeGO:003803040.012
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.012
mitotic cell cycle phase transitionGO:00447721620.012
response to axon injuryGO:004867810.012
response to lipidGO:00339932060.011
signal releaseGO:0023061700.011
glycoprotein metabolic processGO:00091001100.011
hematopoietic or lymphoid organ developmentGO:00485341860.011
negative regulation of cell growthGO:0030308830.011
blastocyst developmentGO:000182430.011
positive regulation of cell cycleGO:00457871400.011
neural tube formationGO:000184130.011
peptidyl tyrosine phosphorylationGO:00181081700.011
regulation of intracellular protein transportGO:00331571230.011
positive regulation of locomotionGO:00400171860.011
myoblast fusionGO:000752010.011
regulation of protein complex assemblyGO:00432541470.011
small molecule biosynthetic processGO:00442831570.011
morphogenesis of an epitheliumGO:0002009600.011
cell morphogenesis involved in differentiationGO:00009041440.011
brain developmentGO:0007420970.011
negative regulation of protein processingGO:00109551420.011
hemopoiesisGO:00300971800.011
tongue developmentGO:004358610.011
cellular response to hormone stimulusGO:00328701250.011
positive regulation of synaptic transmissionGO:005080640.011
morphogenesis of a polarized epitheliumGO:000173830.011
endocytosisGO:00068971590.011
positive regulation of odontogenesisGO:004248230.011
tube morphogenesisGO:0035239950.011
covalent chromatin modificationGO:00165692540.011
convergent extensionGO:006002610.011
sequestering of metal ionGO:0051238240.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.011
protein autophosphorylationGO:00467771230.011
embryonic camera type eye developmentGO:003107620.011
protein targeting to nucleusGO:00447441040.011
negative regulation of cell motilityGO:20001461040.011
histone modificationGO:00165702510.011
regulation of stress activated protein kinase signaling cascadeGO:0070302850.011
regulation of meiotic cell cycleGO:005144540.011
viral life cycleGO:00190581320.011
stress activated mapk cascadeGO:0051403930.011
protein import into nucleusGO:00066061040.011
muscle system processGO:0003012810.011
small molecule catabolic processGO:0044282920.011
ossificationGO:00015031210.011
regulation of cardiac muscle tissue growthGO:005502140.011
protein secretionGO:0009306980.011
neuroendocrine cell differentiationGO:006110120.011
canonical wnt signaling pathway involved in mesenchymal stem cell differentiationGO:004433820.011
positive regulation of reactive oxygen species biosynthetic processGO:190342820.011
chromatin modificationGO:00165682980.011
single organism nuclear importGO:19025931040.011
regulation of actin cytoskeleton organizationGO:00329561160.011
neuroblast proliferationGO:000740540.011
neural tube closureGO:000184330.011
neuron projection developmentGO:00311751060.011
cell proliferation in forebrainGO:002184610.011
organophosphate biosynthetic processGO:00904071630.011
regulation of cell developmentGO:00602841610.011
response to radiationGO:00093141510.011
neural crest cell developmentGO:001403230.010
regulation of cell growthGO:00015581350.010
nuclear importGO:00511701060.010
chemotaxisGO:00069351570.010
peptide transportGO:0015833740.010
microtubule cytoskeleton organizationGO:00002261760.010
cellular response to lipidGO:00713961270.010
associative learningGO:000830610.010
heart morphogenesisGO:0003007480.010
regulation of peptidyl tyrosine phosphorylationGO:00507301080.010
divalent inorganic cation transportGO:00725111580.010
digestive system developmentGO:0055123750.010
tube closureGO:006060630.010
heart field specificationGO:000312820.010
regulation of viral processGO:00507921030.010
regulation of epithelial cell proliferationGO:00506781130.010
carbohydrate metabolic processGO:00059752070.010
reproductive processGO:00224141060.010
divalent metal ion transportGO:00708381520.010
negative regulation of wnt signaling pathwayGO:0030178690.010
pituitary gland developmentGO:002198320.010
negative regulation of testosterone biosynthetic processGO:200022510.010
tube developmentGO:00352951250.010
epidermal cell differentiationGO:0009913450.010
protein homooligomerizationGO:00512601000.010
brain morphogenesisGO:004885410.010
negative regulation of cell fate commitmentGO:001045430.010
neuron developmentGO:00486661130.010
single organism carbohydrate metabolic processGO:00447231930.010
humoral immune responseGO:0006959490.010
somatic muscle developmentGO:000752510.010
cell projection assemblyGO:00300311260.010
regulation of odontogenesisGO:004248140.010
ventral spinal cord developmentGO:002151710.010
sensory perception of painGO:001923340.010
regulation of cell morphogenesisGO:00226041530.010

ISM2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:00501552030.030
nervous system diseaseDOID:8634310.030
disease of metabolismDOID:00146672950.024
eye diseaseDOID:56141490.018
eye and adnexa diseaseDOID:14921500.018
musculoskeletal system diseaseDOID:172230.017
disease of cellular proliferationDOID:145661740.016
cancerDOID:1621670.012
inherited metabolic disorderDOID:6552420.012
organ system cancerDOID:00506861640.012
retinal diseaseDOID:56791180.011