Homo sapiens

30 known processes

LGR4

leucine-rich repeat containing G protein-coupled receptor 4

(Aliases: GPR48)

LGR4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.093
cellular ketone metabolic processGO:0042180800.084
cellular amino acid metabolic processGO:00065201160.068
regulation of cellular ketone metabolic processGO:0010565500.059
cellular amine metabolic processGO:0044106410.058
amine metabolic processGO:0009308440.057
regulation of cellular amine metabolic processGO:0033238110.054
regulation of cellular amino acid metabolic processGO:000652160.054
lipid metabolic processGO:00066293810.052
multicellular organismal agingGO:001025930.045
determination of adult lifespanGO:000834020.045
locomotory behaviorGO:000762610.045
positive regulation of phosphorylationGO:00423273940.044
positive regulation of cellular amino acid metabolic processGO:004576430.043
positive regulation of cellular amine metabolic processGO:003324070.042
nucleoside phosphate catabolic processGO:19012924120.042
canonical wnt signaling pathwayGO:00600701160.039
cellular lipid metabolic processGO:00442553030.038
female gamete generationGO:000729220.037
nucleoside triphosphate metabolic processGO:00091414220.036
system processGO:00030083490.036
Human
ion transmembrane transportGO:00342203380.036
purine ribonucleotide catabolic processGO:00091544040.035
actin filament based processGO:00300292240.035
ras protein signal transductionGO:0007265730.035
purine containing compound catabolic processGO:00725234110.035
positive regulation of protein phosphorylationGO:00019343130.034
ribonucleoside triphosphate metabolic processGO:00091994120.034
glycosyl compound catabolic processGO:19016584130.034
small gtpase mediated signal transductionGO:0007264780.034
organophosphate catabolic processGO:00464344300.034
purine nucleotide catabolic processGO:00061954050.034
purine ribonucleoside metabolic processGO:00461284370.034
epithelium developmentGO:00604292270.033
Mouse
purine nucleoside triphosphate metabolic processGO:00091444120.033
vesicle mediated transportGO:00161923710.033
purine ribonucleoside triphosphate metabolic processGO:00092054110.033
chemical homeostasisGO:00488783060.033
oogenesisGO:004847720.032
regulation of transferase activityGO:00513383550.032
transmembrane transportGO:00550853990.032
positive regulation of transportGO:00510503360.032
purine ribonucleoside catabolic processGO:00461303980.031
negative regulation of catalytic activityGO:00430863350.031
ribonucleoside catabolic processGO:00424544060.031
carbohydrate metabolic processGO:00059752070.031
positive regulation of hydrolase activityGO:00513453310.031
ribonucleotide catabolic processGO:00092614050.031
cation transportGO:00068123310.031
purine ribonucleoside triphosphate catabolic processGO:00092073910.030
ribonucleoside triphosphate catabolic processGO:00092033910.030
positive regulation of catabolic processGO:00098963100.030
nucleoside triphosphate catabolic processGO:00091433940.030
regulation of cell cycleGO:00517263930.030
nucleoside catabolic processGO:00091644080.029
biological adhesionGO:00226103310.029
neuromuscular junction developmentGO:000752830.028
negative regulation of protein metabolic processGO:00512483910.028
positive regulation of cellular component organizationGO:00511303760.028
ion homeostasisGO:00508012300.028
metal ion transportGO:00300012720.028
response to abiotic stimulusGO:00096283360.028
regulation of kinase activityGO:00435493140.028
purine nucleoside catabolic processGO:00061523980.028
purine nucleoside triphosphate catabolic processGO:00091463920.027
regulation of canonical wnt signaling pathwayGO:0060828880.027
cation transmembrane transportGO:00986552380.027
mitotic cell cycleGO:00002783260.027
negative regulation of cellular protein metabolic processGO:00322693530.027
regulation of protein localizationGO:00328802960.027
Mouse
cellular macromolecule catabolic processGO:00442653800.027
negative regulation of cell deathGO:00605483450.026
adult locomotory behaviorGO:000834410.026
membrane organizationGO:00610242920.026
protein catabolic processGO:00301633250.026
inorganic ion transmembrane transportGO:00986602310.026
cell morphogenesisGO:00009022960.026
nucleotide catabolic processGO:00091664080.026
protein modification by small protein conjugationGO:00324463420.026
cytoplasmic transportGO:00164823790.026
segmentationGO:003528240.026
small molecule biosynthetic processGO:00442831570.026
organonitrogen compound biosynthetic processGO:19015662000.025
lipid biosynthetic processGO:00086101770.025
single organism cellular localizationGO:19025803320.025
negative regulation of apoptotic processGO:00430663160.025
carbohydrate derivative biosynthetic processGO:19011372070.025
immune responseGO:00069553070.025
inorganic cation transmembrane transportGO:00986621940.025
single organism carbohydrate metabolic processGO:00447231930.025
wnt signaling pathwayGO:00160551560.025
regulation of anatomical structure morphogenesisGO:00226032860.024
Mouse
cellular chemical homeostasisGO:00550821800.024
oxidation reduction processGO:00551143960.024
cell adhesionGO:00071553250.024
negative regulation of phosphorus metabolic processGO:00105632670.024
multicellular organismal homeostasisGO:0048871670.024
regulation of cell differentiationGO:00455953930.024
negative regulation of phosphate metabolic processGO:00459362670.024
mitotic cell cycle processGO:19030472860.024
regenerationGO:003109940.024
cellular component morphogenesisGO:00329893140.024
enzyme linked receptor protein signaling pathwayGO:00071673030.023
cation homeostasisGO:00550801890.023
organ morphogenesisGO:00098871470.023
Mouse
nervous system developmentGO:00073992930.023
cellular homeostasisGO:00197251960.023
positive regulation of cellular catabolic processGO:00313312840.023
mapk cascadeGO:00001652880.023
monocarboxylic acid metabolic processGO:00327871850.023
memoryGO:000761330.023
circulatory system developmentGO:00723592620.023
anterior posterior axis specificationGO:000994820.023
response to oxygen containing compoundGO:19017003690.023
morphogenesis of a polarized epitheliumGO:000173830.023
regulation of protein kinase activityGO:00458592890.022
microtubule based processGO:00070172100.022
cellular response to dna damage stimulusGO:00069743790.022
rho protein signal transductionGO:0007266260.022
innate immune responseGO:00450871780.022
metencephalon developmentGO:002203720.022
secretionGO:00469032540.022
Mouse
cellular response to endogenous stimulusGO:00714953360.022
cellular protein catabolic processGO:00442572610.022
establishment of planar polarityGO:000173630.022
cellular macromolecular complex assemblyGO:00346223240.022
cardiac muscle cell contractionGO:008600340.022
maintenance of locationGO:00512351120.022
morphogenesis of embryonic epitheliumGO:001633140.022
single organism membrane organizationGO:00448022680.021
regulation of locomotionGO:00400123290.021
Human
blastoderm segmentationGO:000735020.021
hindbrain developmentGO:003090230.021
actin mediated cell contractionGO:0070252120.021
signal transduction by phosphorylationGO:00230142970.021
regulation of nucleotide metabolic processGO:00061402690.021
regulation of vesicle mediated transportGO:00606271300.021
intracellular protein transportGO:00068862700.021
regulation of cell motilityGO:20001452990.021
Human
negative regulation of programmed cell deathGO:00430693210.021
positive regulation of nucleotide metabolic processGO:00459812300.021
regulation of cellular component movementGO:00512703340.021
Human
regulation of cellular component biogenesisGO:00440872810.021
negative regulation of non canonical wnt signaling pathwayGO:200005110.021
dephosphorylationGO:00163112090.020
negative regulation of cellular amine metabolic processGO:003323930.020
proteolysis involved in cellular protein catabolic processGO:00516032440.020
protein localization to organelleGO:00333652800.020
protein ubiquitinationGO:00165673140.020
peripheral nervous system developmentGO:000742220.020
negative regulation of cellular amino acid metabolic processGO:004576320.020
organic acid biosynthetic processGO:0016053970.020
regulation of cell cycle processGO:00105642660.020
defense responseGO:00069523150.020
cell developmentGO:00484683280.020
cell projection organizationGO:00300302520.020
neurological system processGO:00508771630.020
Human
positive regulation of purine nucleotide metabolic processGO:19005442270.020
metal ion homeostasisGO:00550651690.020
cellular cation homeostasisGO:00300031630.020
actin filament based movementGO:0030048170.020
regulation of mapk cascadeGO:00434082620.019
embryonic epithelial tube formationGO:000183840.019
regulation of proteolysisGO:00301622930.019
regulation of purine nucleotide metabolic processGO:19005422640.019
receptor metabolic processGO:0043112810.019
negative regulation of cellular component organizationGO:00511292350.019
positive regulation of developmental processGO:00510943140.019
Mouse
anion transportGO:00068201610.019
positive regulation of apoptotic processGO:00430652460.019
ribonucleoside monophosphate metabolic processGO:00091611870.019
negative regulation of multicellular organismal processGO:00512413170.019
Mouse
spermatid differentiationGO:004851540.019
regulation of nucleoside metabolic processGO:00091182090.019
positive regulation of organelle organizationGO:00106381950.019
cellular response to oxygen containing compoundGO:19017012760.019
positive regulation of immune system processGO:00026842830.019
Mouse
apoptotic signaling pathwayGO:00971902680.018
guanosine containing compound catabolic processGO:19010692390.018
carboxylic acid biosynthetic processGO:0046394970.018
oocyte developmentGO:004859910.018
inner ear morphogenesisGO:004247240.018
modification dependent macromolecule catabolic processGO:00436322120.018
positive regulation of cell deathGO:00109422630.018
regulation of wnt signaling pathwayGO:00301111230.018
growthGO:00400072020.018
anatomical structure homeostasisGO:00602491000.018
positive regulation of cell proliferationGO:00082843010.018
purine ribonucleoside monophosphate metabolic processGO:00091671860.018
secretion by cellGO:00329402260.018
Mouse
negative regulation of intracellular signal transductionGO:19025321830.018
regulation of nucleotide catabolic processGO:00308112050.018
protein maturationGO:00516042330.018
regulation of protein transportGO:00512232130.018
Mouse
guanosine containing compound metabolic processGO:19010682440.018
single organism cell adhesionGO:00986021790.018
cardiovascular system developmentGO:00723582620.018
response to organic cyclic compoundGO:00140702040.018
epidermis morphogenesisGO:004873030.018
matingGO:000761810.018
regulation of cellular response to stressGO:00801352440.018
regulation of purine nucleotide catabolic processGO:00331212050.018
purine nucleoside monophosphate metabolic processGO:00091261860.017
establishment of tissue polarityGO:000716430.017
posttranscriptional regulation of gene expressionGO:00106082130.017
cellular ion homeostasisGO:00068731680.017
response to external biotic stimulusGO:00432072610.017
associative learningGO:000830610.017
spermatid developmentGO:000728640.017
blood vessel developmentGO:00015681720.017
reactive oxygen species biosynthetic processGO:190340940.017
protein processingGO:00164852260.017
organophosphate biosynthetic processGO:00904071630.017
positive regulation of kinase activityGO:00336742040.017
positive regulation of transferase activityGO:00513472270.017
positive regulation of nucleoside metabolic processGO:00459791860.017
modification dependent protein catabolic processGO:00199412090.017
cell divisionGO:00513011680.017
regulation of cell migrationGO:00303342890.017
Human
positive regulation of programmed cell deathGO:00430682490.017
neuroblast proliferationGO:000740540.017
neurotransmitter secretionGO:000726940.017
organic hydroxy compound metabolic processGO:19016151470.017
regulation of cytoskeleton organizationGO:00514931770.017
ubiquitin dependent protein catabolic processGO:00065112060.017
cell fate determinationGO:000170930.017
negative regulation of transportGO:00510511760.017
Mouse
oocyte differentiationGO:000999420.017
negative regulation of hydrolase activityGO:00513461820.017
reactive nitrogen species metabolic processGO:200105730.017
gtp metabolic processGO:00460392390.017
nucleoside monophosphate metabolic processGO:00091231910.016
anatomical structure formation involved in morphogenesisGO:00486462840.016
forelimb morphogenesisGO:003513640.016
regulation of establishment of protein localizationGO:00702012420.016
Mouse
cellular metal ion homeostasisGO:00068751460.016
nerve developmentGO:002167540.016
tripartite regional subdivisionGO:000735120.016
gtp catabolic processGO:00061842370.016
microtubule cytoskeleton organizationGO:00002261760.016
actin cytoskeleton organizationGO:00300362070.016
regulation of meiotic cell cycleGO:005144540.016
reactive oxygen species metabolic processGO:0072593750.016
cerebellum developmentGO:002154920.016
nitrogen compound transportGO:00717051910.016
cellular protein complex assemblyGO:00436231880.016
small molecule catabolic processGO:0044282920.016
regulation of sequence specific dna binding transcription factor activityGO:00510902110.016
generation of neuronsGO:00486991520.016
neural tube formationGO:000184130.016
regulation of secretionGO:00510461940.016
Mouse
negative regulation of protein modification processGO:00314002000.016
glycoprotein metabolic processGO:00091001100.016
photoreceptor cell differentiationGO:004653020.016
regulation of response to external stimulusGO:00321012220.016
response to other organismGO:00517072610.016
neurogenesisGO:00220081690.016
regulation of multi organism processGO:00439001570.016
response to nitrogen compoundGO:19016981840.016
endomembrane system organizationGO:00102561960.016
motor neuron axon guidanceGO:000804520.016
limbic system developmentGO:002176130.016
positive regulation of purine nucleotide catabolic processGO:00331231850.016
organelle fissionGO:00482851490.016
negative regulation of cell proliferationGO:00082852280.016
fatty acid metabolic processGO:00066311150.015
stem cell divisionGO:001714520.015
positive regulation of protein kinase activityGO:00458601900.015
regulation of gtp catabolic processGO:00331241800.015
cell growthGO:00160491600.015
salivary gland morphogenesisGO:000743540.015
atp metabolic processGO:00460341760.015
anterior posterior axis specification embryoGO:000859520.015
response to biotic stimulusGO:00096072760.015
divalent inorganic cation homeostasisGO:00725071360.015
endocytosisGO:00068971590.015
protein localization to membraneGO:00726571600.015
interspecies interaction between organismsGO:00444191560.015
regulation of ion transportGO:00432691890.015
tissue homeostasisGO:0001894630.015
regulation of reactive oxygen species biosynthetic processGO:190342630.015
negative regulation of phosphorylationGO:00423261740.015
positive regulation of nucleotide catabolic processGO:00308131850.015
regulation of peptidase activityGO:00525471800.015
response to hormoneGO:00097251750.015
rhythmic behaviorGO:000762220.015
release of cytoplasmic sequestered nf kappabGO:000858840.015
cell cycle phase transitionGO:00447701730.015
glycerolipid metabolic processGO:00464861070.015
blood vessel morphogenesisGO:00485141620.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.015
protein targetingGO:00066051870.015
divalent inorganic cation transportGO:00725111580.015
nucleoside monophosphate catabolic processGO:00091251590.015
regulation of protein serine threonine kinase activityGO:00719001790.015
regulation of gtpase activityGO:00430871800.015
retina homeostasisGO:0001895420.015
negative regulation of cell cycleGO:00457861930.014
ribonucleoside monophosphate catabolic processGO:00091581580.014
primary neural tube formationGO:001402030.014
divalent metal ion transportGO:00708381520.014
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.014
positive regulation of mapk cascadeGO:00434101900.014
positive regulation of gtpase activityGO:00435471660.014
visual behaviorGO:000763220.014
rna interferenceGO:001624640.014
angiogenesisGO:00015251470.014
tissue regenerationGO:004224630.014
response to cytokineGO:00340972320.014
purine ribonucleoside monophosphate catabolic processGO:00091691580.014
positive regulation of locomotionGO:00400171860.014
Human
multi organism cellular processGO:00447641560.014
organelle assemblyGO:00709251760.014
mitotic cell cycle phase transitionGO:00447721620.014
regulation of secretion by cellGO:19035301770.014
Mouse
negative regulation of developmental processGO:00510932470.014
purine nucleoside monophosphate catabolic processGO:00091281580.014
calcium ion homeostasisGO:00550741220.014
rna processingGO:00063962550.014
regulation of intracellular transportGO:00323861950.014
hindlimb morphogenesisGO:003513720.014
positive regulation of cell migrationGO:00303351720.014
Human
regulation of synaptic plasticityGO:004816730.014
epithelial cell differentiationGO:00308551410.014
protein oligomerizationGO:00512591730.014
negative regulation of transferase activityGO:00513481240.014
epithelium migrationGO:00901321190.014
cell part morphogenesisGO:00329901370.014
compound eye developmentGO:004874910.014
chromatin modificationGO:00165682980.014
chromatin organizationGO:00063253510.014
cell activationGO:00017752130.014
regulation of neural precursor cell proliferationGO:200017740.014
positive regulation of synaptic transmissionGO:005080640.014
regulation of ras protein signal transductionGO:00465781550.014
tube closureGO:006060630.014
forebrain generation of neuronsGO:002187230.014
regulation of growthGO:00400081650.014
circadian behaviorGO:004851220.014
somitogenesisGO:000175620.014
proteasomal protein catabolic processGO:00104981760.013
response to lipidGO:00339932060.013
negative regulation of wnt signaling pathwayGO:0030178690.013
cytokine productionGO:00018162470.013
Mouse
organ formationGO:004864530.013
regulation of immune responseGO:00507762010.013
Mouse
regulation of membrane potentialGO:0042391950.013
muscle system processGO:0003012810.013
response to growth factorGO:00708482050.013
single organismal cell cell adhesionGO:00163371480.013
regulation of endopeptidase activityGO:00525481700.013
sulfur compound metabolic processGO:00067901010.013
cellular response to cytokine stimulusGO:00713451810.013
regulation of mitotic cell cycleGO:00073461890.013
lipid localizationGO:00108761060.013
regulation of protein catabolic processGO:00421761550.013
organic anion transportGO:00157111030.013
monovalent inorganic cation transportGO:00156721280.013
phospholipid metabolic processGO:0006644990.013
tissue morphogenesisGO:0048729960.013
Mouse
symbiosis encompassing mutualism through parasitismGO:00444031560.013
histone modificationGO:00165702510.013
response to axon injuryGO:004867810.013
vasculature developmentGO:00019441810.013
atp catabolic processGO:00062001570.013
glycoprotein biosynthetic processGO:0009101910.013
sequestering of metal ionGO:0051238240.013
positive regulation of gtp catabolic processGO:00331261660.013
regulation of cytokine productionGO:00018172320.013
Mouse
mitochondrion organizationGO:00070051560.013
syncytium formation by plasma membrane fusionGO:000076820.013
meiosis iGO:000712740.013
response to fungusGO:000962040.013
regulation of reactive oxygen species metabolic processGO:2000377410.013
neural tube closureGO:000184330.013
viral processGO:00160321460.013
long term memoryGO:000761620.013
cell projection morphogenesisGO:00488581290.013
carboxylic acid catabolic processGO:0046395710.013
regulation of actin filament based processGO:00329701410.013
covalent chromatin modificationGO:00165692540.013
ameboidal type cell migrationGO:00016671350.013
calcium ion transportGO:00068161470.013
regulation of cell morphogenesisGO:00226041530.013
embryonic forelimb morphogenesisGO:003511540.013
regulation of meiosisGO:004002030.013
regulation of protein complex assemblyGO:00432541470.013
epithelial cell proliferationGO:00506731280.013
Mouse
central nervous system developmentGO:00074171230.013
cellular divalent inorganic cation homeostasisGO:00725031280.013
hemopoiesisGO:00300971800.013
immune system developmentGO:00025201950.013
nuclear divisionGO:00002801280.013
positive regulation of immune responseGO:00507781590.013
Mouse
cellular response to growth factor stimulusGO:00713631970.013
positive regulation of cell differentiationGO:00455972110.013
protein localization to nucleusGO:00345041360.013
establishment of protein localization to membraneGO:00901501210.013
thymus developmentGO:004853830.012
regulation of protein maturationGO:19033171500.012
regulation of cell developmentGO:00602841610.012
hair follicle morphogenesisGO:003106920.012
alcohol metabolic processGO:00060661140.012
peptidyl tyrosine phosphorylationGO:00181081700.012
neural crest cell developmentGO:001403230.012
organic acid catabolic processGO:0016054710.012
sensory perceptionGO:00076001030.012
striated muscle contractionGO:0006941520.012
cellular response to lipidGO:00713961270.012
epithelial cell migrationGO:00106311190.012
immune effector processGO:00022521590.012
head developmentGO:00603221080.012
axis elongationGO:000340140.012
glial cell migrationGO:000834740.012
tissue migrationGO:00901301190.012
sex determinationGO:000753030.012
establishment or maintenance of bipolar cell polarityGO:006124520.012
cerebral cortex cell migrationGO:002179530.012
specification of organ identityGO:001009230.012
peptidyl tyrosine modificationGO:00182121700.012
cofactor metabolic processGO:0051186870.012
g protein coupled receptor signaling pathwayGO:00071862070.012
cell projection assemblyGO:00300311260.012
regulation of apoptotic signaling pathwayGO:20012331750.012
negative regulation of catabolic processGO:00098951040.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
establishment of protein localization to organelleGO:00725941720.012
positive regulation of proteolysisGO:00458621420.012
regulation of cytoplasmic transportGO:19036491490.012
sequestering of calcium ionGO:0051208170.012
alpha amino acid metabolic processGO:1901605720.012
neuron developmentGO:00486661130.012
positive regulation of protein transportGO:00512221350.012
nucleus localizationGO:005164710.012
spinal cord developmentGO:002151040.012
nuclear transportGO:00511691790.012
response to organonitrogen compoundGO:00102431560.012
positive regulation of cellular component movementGO:00512721810.012
Human
response to woundingGO:00096111680.012
epithelial tube branching involved in lung morphogenesisGO:006044140.012
regulation of small gtpase mediated signal transductionGO:00510561560.012
startle responseGO:000196430.012
regulation of transmembrane transportGO:00347621390.012
protein autophosphorylationGO:00467771230.012
lipid modificationGO:0030258840.012
cardiac muscle contractionGO:0060048340.012
negative regulation of protein phosphorylationGO:00019331400.012
monocarboxylic acid biosynthetic processGO:0072330670.012
response to inorganic substanceGO:00100351270.012
regulation of cell growthGO:00015581350.012
endosomal transportGO:00161971290.012
positive regulation of ras gtpase activityGO:00323201170.012
cellular response to organic cyclic compoundGO:00714071270.012
embryo developmentGO:00097901230.012
sensory perception of painGO:001923340.012
keratinizationGO:003142420.012
meiotic chromosome segregationGO:004513240.011
neuron differentiationGO:00301821380.011
regulation of ras gtpase activityGO:00323181280.011
male meiosisGO:000714010.011
sensory perception of smellGO:000760820.011
glycerophospholipid metabolic processGO:0006650840.011
myoblast fusionGO:000752010.011
establishment or maintenance of apical basal cell polarityGO:003508820.011
hematopoietic or lymphoid organ developmentGO:00485341860.011
regulation of neurotransmitter secretionGO:004692830.011
regulation of protein processingGO:00706131500.011

LGR4 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:6552420.052
disease of metabolismDOID:00146672950.052
sensory system diseaseDOID:00501552030.027
nervous system diseaseDOID:8634310.027
musculoskeletal system diseaseDOID:172230.025
central nervous system diseaseDOID:3311860.022
disease of cellular proliferationDOID:145661740.021
cancerDOID:1621670.021
organ system cancerDOID:00506861640.019
eye and adnexa diseaseDOID:14921500.018
eye diseaseDOID:56141490.018
muscle tissue diseaseDOID:661130.017
muscular diseaseDOID:00800001140.017
cardiovascular system diseaseDOID:12871060.017
immune system diseaseDOID:29141550.017
myopathyDOID:4231040.014
retinal diseaseDOID:56791180.014
bone diseaseDOID:0080001880.014
connective tissue diseaseDOID:651090.014
neurodegenerative diseaseDOID:12891020.014
carbohydrate metabolic disorderDOID:2978550.013
amino acid metabolic disorderDOID:9252500.013
brain diseaseDOID:936730.012
heart diseaseDOID:114680.012
hematopoietic system diseaseDOID:741000.012
retinal degenerationDOID:8466890.011