Homo sapiens

36 known processes

MLL3

myeloid/lymphoid or mixed-lineage leukemia 3

(Aliases: KMT2C,FLJ38309,HALR,MGC119851,MGC119852,MGC119853,DKFZp686C08112,FLJ12625,KIAA1506)

MLL3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chromatin organizationGO:00063253510.956
chromatin modificationGO:00165682980.940
protein alkylationGO:0008213740.921
covalent chromatin modificationGO:00165692540.900
histone lysine methylationGO:0034968500.839
histone h3 k4 methylationGO:0051568270.793
histone modificationGO:00165702510.731
cellular response to dna damage stimulusGO:00069743790.521
macromolecule methylationGO:0043414970.454
determination of adult lifespanGO:000834020.433
embryonic placenta developmentGO:000189210.425
methylationGO:00322591060.336
multicellular organismal agingGO:001025930.306
amine metabolic processGO:0009308440.301
cardiovascular system developmentGO:00723582620.301
protein methylationGO:0006479740.225
peptidyl lysine methylationGO:0018022370.222
dna templated transcription initiationGO:0006352350.198
cellular ketone metabolic processGO:0042180800.183
regulation of cellular ketone metabolic processGO:0010565500.155
histone methylationGO:0016571600.153
protein acetylationGO:00064731160.146
cellular amino acid metabolic processGO:00065201160.138
primary neural tube formationGO:001402030.133
circulatory system developmentGO:00723592620.125
positive regulation of catabolic processGO:00098963100.118
regulation of protein serine threonine kinase activityGO:00719001790.111
heart developmentGO:0007507950.100
post embryonic developmentGO:000979120.084
internal peptidyl lysine acetylationGO:0018393970.079
positive regulation of cellular amino acid metabolic processGO:004576430.078
cell activationGO:00017752130.072
regulation of response to dna damage stimulusGO:2001020940.071
neuron projection developmentGO:00311751060.069
small gtpase mediated signal transductionGO:0007264780.068
nervous system developmentGO:00073992930.066
regulation of protein complex assemblyGO:00432541470.065
single organism reproductive processGO:0044702980.065
positive regulation of cell differentiationGO:00455972110.063
response to axon injuryGO:004867810.062
cellular amine metabolic processGO:0044106410.061
cellular component morphogenesisGO:00329893140.061
leukocyte activationGO:00453211640.057
regulation of growthGO:00400081650.057
signal transduction by phosphorylationGO:00230142970.057
immune responseGO:00069553070.056
cell projection morphogenesisGO:00488581290.054
histone h3 k27 demethylationGO:007155730.054
cellular macromolecular complex assemblyGO:00346223240.054
regulation of protein kinase activityGO:00458592890.053
actin cytoskeleton organizationGO:00300362070.052
embryonic organ developmentGO:0048568360.052
purine ribonucleotide catabolic processGO:00091544040.052
positive regulation of protein kinase activityGO:00458601900.051
positive regulation of protein phosphorylationGO:00019343130.051
neuron projection regenerationGO:003110210.050
actin filament based processGO:00300292240.049
positive regulation of organelle organizationGO:00106381950.048
Fly
segmentationGO:003528240.048
immune system developmentGO:00025201950.047
reproductive processGO:00224141060.047
chordate embryonic developmentGO:0043009340.046
myeloid cell differentiationGO:00300991170.046
protein dna complex subunit organizationGO:0071824800.046
negative regulation of cellular protein metabolic processGO:00322693530.045
negative regulation of protein metabolic processGO:00512483910.045
mapk cascadeGO:00001652880.045
negative regulation of cellular amino acid metabolic processGO:004576320.045
positive regulation of mapk cascadeGO:00434101900.044
regulation of mapk cascadeGO:00434082620.044
glycosyl compound catabolic processGO:19016584130.044
embryonic epithelial tube formationGO:000183840.041
collateral sproutingGO:004866820.041
immune effector processGO:00022521590.041
regulation of protein processingGO:00706131500.041
histone demethylationGO:0016577150.041
response to organic cyclic compoundGO:00140702040.040
Human
regulation of cellular amine metabolic processGO:0033238110.040
mrna metabolic processGO:00160711750.040
regenerationGO:003109940.040
regulation of kinase activityGO:00435493140.039
head developmentGO:00603221080.039
cell part morphogenesisGO:00329901370.038
positive regulation of nucleotide catabolic processGO:00308131850.038
regulation of neurotransmitter secretionGO:004692830.038
brain developmentGO:0007420970.037
actin filament organizationGO:00070151280.037
protein acylationGO:00435431380.037
purine nucleotide catabolic processGO:00061954050.037
peptidyl lysine dimethylationGO:001802730.037
guanosine containing compound catabolic processGO:19010692390.037
negative regulation of protein maturationGO:19033181420.036
cellular response to organic cyclic compoundGO:00714071270.036
protein deacylationGO:0035601390.036
anterior posterior axis specificationGO:000994820.036
morphogenesis of embryonic epitheliumGO:001633140.036
negative regulation of programmed cell deathGO:00430693210.036
peptidyl threonine modificationGO:0018210450.035
purine ribonucleoside catabolic processGO:00461303980.035
anatomical structure homeostasisGO:00602491000.034
regulation of multi organism processGO:00439001570.034
ubiquitin dependent protein catabolic processGO:00065112060.033
response to salt stressGO:000965130.033
regulation of developmental growthGO:0048638300.033
female gamete generationGO:000729220.033
regulation of gene expression epigeneticGO:0040029730.032
gene silencingGO:0016458490.032
response to steroid hormoneGO:0048545800.031
Human
purine nucleoside catabolic processGO:00061523980.031
negative regulation of intracellular signal transductionGO:19025321830.031
purine nucleoside triphosphate metabolic processGO:00091444120.031
hematopoietic or lymphoid organ developmentGO:00485341860.031
regulation of map kinase activityGO:00434051080.031
regulation of purine nucleotide metabolic processGO:19005422640.031
nucleoside triphosphate metabolic processGO:00091414220.031
protein processingGO:00164852260.031
response to acid chemicalGO:0001101660.030
regulation of myeloid leukocyte differentiationGO:0002761390.030
peptidyl threonine phosphorylationGO:0018107410.030
purine nucleoside triphosphate catabolic processGO:00091463920.029
regulation of cellular amino acid metabolic processGO:000652160.029
cellular protein catabolic processGO:00442572610.029
oogenesisGO:004847720.029
regulation of cellular response to stressGO:00801352440.029
single organism carbohydrate metabolic processGO:00447231930.029
regulation of small gtpase mediated signal transductionGO:00510561560.029
response to oxygen containing compoundGO:19017003690.029
negative regulation of cellular amine metabolic processGO:003323930.028
protein ubiquitinationGO:00165673140.028
positive regulation of purine nucleotide catabolic processGO:00331231850.028
peptidyl serine modificationGO:00182091060.028
cell developmentGO:00484683280.027
intracellular receptor signaling pathwayGO:00305221040.027
Human
nucleotide catabolic processGO:00091664080.027
cell projection organizationGO:00300302520.027
tube closureGO:006060630.027
nucleoside triphosphate catabolic processGO:00091433940.027
regulation of nucleotide metabolic processGO:00061402690.027
hemopoiesisGO:00300971800.027
peptidyl lysine modificationGO:00182051440.026
axon regenerationGO:003110310.026
positive regulation of cell proliferationGO:00082843010.026
Human
regulation of purine nucleotide catabolic processGO:00331212050.026
regulation of protein maturationGO:19033171500.026
cell morphogenesisGO:00009022960.026
transdifferentiationGO:006029020.026
ameboidal type cell migrationGO:00016671350.026
antimicrobial humoral responseGO:0019730260.026
regulation of response to external stimulusGO:00321012220.026
neutrophil mediated immunityGO:000244640.025
tube developmentGO:00352951250.025
positive regulation of cellular component organizationGO:00511303760.025
Fly
ribonucleotide catabolic processGO:00092614050.025
dephosphorylationGO:00163112090.025
regulation of locomotionGO:00400123290.025
negative regulation of phosphate metabolic processGO:00459362670.025
regulation of nucleoside metabolic processGO:00091182090.024
cellular response to oxygen containing compoundGO:19017012760.024
protein maturationGO:00516042330.024
organophosphate catabolic processGO:00464344300.024
blood vessel developmentGO:00015681720.023
negative regulation of proteolysisGO:00458611320.023
embryo developmentGO:00097901230.023
positive regulation of cellular amine metabolic processGO:003324070.023
negative regulation of catabolic processGO:00098951040.023
dna damage checkpointGO:0000077680.023
epithelium developmentGO:00604292270.022
ras protein signal transductionGO:0007265730.022
gtp catabolic processGO:00061842370.022
agingGO:0007568660.022
positive regulation of gtpase activityGO:00435471660.022
negative regulation of catalytic activityGO:00430863350.022
protein catabolic processGO:00301633250.022
regulation of immune responseGO:00507762010.022
endothelial cell migrationGO:0043542860.022
negative regulation of apoptotic processGO:00430663160.022
purine containing compound catabolic processGO:00725234110.022
response to woundingGO:00096111680.021
nucleoside catabolic processGO:00091644080.021
cellular response to growth factor stimulusGO:00713631970.021
response to estrogenGO:0043627470.021
Human
negative regulation of cellular component organizationGO:00511292350.021
regulation of protein catabolic processGO:00421761550.021
regulation of nucleotide catabolic processGO:00308112050.021
proteolysis involved in cellular protein catabolic processGO:00516032440.021
carbohydrate metabolic processGO:00059752070.021
ribonucleoside triphosphate catabolic processGO:00092033910.021
cell morphogenesis involved in neuron differentiationGO:0048667440.020
negative regulation of chromatin silencingGO:003193640.020
negative regulation of mitotic cell cycle phase transitionGO:1901991850.020
rna catabolic processGO:0006401710.020
behaviorGO:00076101120.020
mitotic sister chromatid segregationGO:0000070530.020
reactive nitrogen species metabolic processGO:200105730.019
establishment of nucleus localizationGO:004002310.019
system processGO:00030083490.019
tissue migrationGO:00901301190.019
blood vessel morphogenesisGO:00485141620.019
positive regulation of myeloid leukocyte differentiationGO:0002763240.019
protein dealkylationGO:0008214170.019
regulation of proteasomal protein catabolic processGO:0061136870.019
nuclear migrationGO:000709710.019
cell morphogenesis involved in differentiationGO:00009041440.019
positive regulation of cellular catabolic processGO:00313312840.019
regulation of synaptic vesicle transportGO:190280330.019
compound eye developmentGO:004874910.019
Fly
purine ribonucleoside metabolic processGO:00461284370.019
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.019
demethylationGO:0070988370.018
ribonucleoside triphosphate metabolic processGO:00091994120.018
response to nitrogen compoundGO:19016981840.018
nucleoside phosphate catabolic processGO:19012924120.018
purine ribonucleoside triphosphate metabolic processGO:00092054110.018
neuromuscular junction developmentGO:000752830.018
cell growthGO:00160491600.018
regulation of autophagyGO:0010506520.018
positive regulation of immune system processGO:00026842830.018
negative regulation of synaptic transmissionGO:005080520.018
ribonucleoside catabolic processGO:00424544060.018
regulation of dna metabolic processGO:00510521530.018
multi organism reproductive processGO:0044703540.018
guanosine containing compound metabolic processGO:19010682440.018
negative regulation of phosphorylationGO:00423261740.018
negative regulation of ruffle assemblyGO:190002830.017
negative regulation of protein modification processGO:00314002000.017
protein autophosphorylationGO:00467771230.017
regulation of cellular component movementGO:00512703340.017
macromolecule deacylationGO:0098732410.017
regulation of chromosome organizationGO:00330441030.017
Fly
respiratory gaseous exchangeGO:000758530.017
vasculature developmentGO:00019441810.017
apoptotic signaling pathwayGO:00971902680.017
cation transmembrane transportGO:00986552380.017
positive regulation of cell deathGO:00109422630.017
regulation of transferase activityGO:00513383550.017
blastoderm segmentationGO:000735020.017
neurotransmitter secretionGO:000726940.017
nucleosome organizationGO:0034728660.016
modification dependent protein catabolic processGO:00199412090.016
inner ear morphogenesisGO:004247240.016
positive regulation of immunoglobulin mediated immune responseGO:000289140.016
gtp metabolic processGO:00460392390.016
regulation of granulocyte differentiationGO:0030852110.016
positive regulation of purine nucleotide metabolic processGO:19005442270.016
mitotic cell cycle checkpointGO:0007093680.016
cellular carbohydrate metabolic processGO:0044262840.016
negative regulation of cell cycle processGO:00109481210.016
cellular response to lipidGO:00713961270.016
positive regulation of nucleoside metabolic processGO:00459791860.016
epithelium migrationGO:00901321190.016
cytokine productionGO:00018162470.016
negative regulation of phosphorus metabolic processGO:00105632670.016
positive regulation of transferase activityGO:00513472270.016
regulation of cellular component biogenesisGO:00440872810.016
interleukin 6 productionGO:0032635370.016
maintenance of locationGO:00512351120.015
cellular macromolecule catabolic processGO:00442653800.015
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.015
nucleus localizationGO:005164710.015
rna 3 end processingGO:0031123350.015
positive regulation of kinase activityGO:00336742040.015
positive regulation of growthGO:0045927580.015
positive regulation of cell growthGO:0030307480.015
response to other organismGO:00517072610.015
purine ribonucleoside triphosphate catabolic processGO:00092073910.015
organonitrogen compound biosynthetic processGO:19015662000.015
erythrocyte homeostasisGO:0034101310.015
reactive oxygen species biosynthetic processGO:190340940.015
neural tube formationGO:000184130.015
metencephalon developmentGO:002203720.015
proteasomal protein catabolic processGO:00104981760.015
response to retinoic acidGO:0032526330.015
inorganic cation transmembrane transportGO:00986621940.014
developmental process involved in reproductionGO:0003006660.014
rho protein signal transductionGO:0007266260.014
transcription initiation from rna polymerase ii promoterGO:0006367270.014
regulation of gtpase activityGO:00430871800.014
activation of protein kinase activityGO:0032147900.014
positive regulation of myeloid cell differentiationGO:0045639390.014
histone acetylationGO:0016573930.014
dna repairGO:00062811980.014
leukocyte mediated immunityGO:0002443590.014
negative regulation of cell cycleGO:00457861930.014
positive regulation of nf kappab transcription factor activityGO:0051092810.014
cd4 positive alpha beta t cell differentiation involved in immune responseGO:000229440.014
endocytosisGO:00068971590.014
negative regulation of protein processingGO:00109551420.013
positive regulation of gtp catabolic processGO:00331261660.013
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.013
synaptic vesicle exocytosisGO:001607930.013
cytoplasmic transportGO:00164823790.013
positive regulation of reactive oxygen species metabolic processGO:2000379240.013
regulation of protein transportGO:00512232130.013
epithelial cell proliferationGO:00506731280.013
reproductive structure developmentGO:0048608550.013
regulation of gtp catabolic processGO:00331241800.013
endocardial cell differentiationGO:006095620.013
dna integrity checkpointGO:0031570710.013
positive regulation of nucleotide metabolic processGO:00459812300.013
negative regulation of organelle organizationGO:00106391260.013
dna conformation changeGO:00711031130.013
positive regulation of leukocyte differentiationGO:1902107370.013
reproductive system developmentGO:0061458560.013
positive regulation of cytokine productionGO:00018191670.013
telomere organizationGO:0032200330.012
histone lysine demethylationGO:0070076140.012
oocyte differentiationGO:000999420.012
neurogenesisGO:00220081690.012
positive regulation of dna metabolic processGO:0051054730.012
protein modification by small protein conjugationGO:00324463420.012
lymphocyte activationGO:00466491330.012
protein polymerizationGO:0051258710.012
internal protein amino acid acetylationGO:00064751010.012
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.012
neural tube closureGO:000184330.012
cellular amide metabolic processGO:0043603690.012
oocyte developmentGO:004859910.012
positive regulation of programmed cell deathGO:00430682490.012
regulation of erk1 and erk2 cascadeGO:0070372990.012
response to organonitrogen compoundGO:00102431560.012
canonical wnt signaling pathwayGO:00600701160.012
nucleocytoplasmic transportGO:00069131760.012
positive regulation of protein serine threonine kinase activityGO:00719021190.012
myosin filament organizationGO:003103320.012
organic hydroxy compound metabolic processGO:19016151470.012
forelimb morphogenesisGO:003513640.012
cell cycle phase transitionGO:00447701730.012
positive regulation of erk1 and erk2 cascadeGO:0070374750.012
negative regulation of hydrolase activityGO:00513461820.012
cellular protein complex assemblyGO:00436231880.012
regulation of chromatin modificationGO:1903308510.011
Fly
spermatid differentiationGO:004851540.011
response to radiationGO:00093141510.011
locomotory behaviorGO:000762610.011
erythrocyte developmentGO:004882130.011
response to abiotic stimulusGO:00096283360.011
vesicle mediated transportGO:00161923710.011
regulation of dephosphorylationGO:0035303960.011
mitotic cell cycle processGO:19030472860.011
regulation of synaptic vesicle exocytosisGO:200030020.011
protein demethylationGO:0006482170.011
divalent inorganic cation transportGO:00725111580.011
mrna processingGO:00063971330.011
cellular response to acid chemicalGO:0071229440.011
establishment of organelle localizationGO:0051656590.011
microtubule based processGO:00070172100.011
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145250.011
ncrna processingGO:0034470830.011
regulation of epithelial cell migrationGO:0010632930.011
actin filament polymerizationGO:0030041450.011
ion transmembrane transportGO:00342203380.011
regulation of myeloid cell differentiationGO:0045637810.011
negative regulation of peptidase activityGO:0010466910.011
regulation of synaptic plasticityGO:004816730.011
mrna catabolic processGO:0006402560.010
regulation of cell divisionGO:00513021160.010
multicellular organismal reproductive processGO:0048609400.010
regulation of secretion by cellGO:19035301770.010
photoreceptor cell differentiationGO:004653020.010
rna processingGO:00063962550.010
memoryGO:000761330.010
positive regulation of cellular component biogenesisGO:00440891580.010
regulation of proteolysisGO:00301622930.010
regulation of peptidase activityGO:00525471800.010
regulation of b cell activationGO:0050864240.010
cellular lipid metabolic processGO:00442553030.010
mitotic cell cycleGO:00002783260.010
peptidyl serine phosphorylationGO:00181051010.010
positive regulation of transportGO:00510503360.010
positive regulation of hydrolase activityGO:00513453310.010
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.010
actin filament bundle organizationGO:0061572540.010
striated muscle myosin thick filament assemblyGO:007168820.010
regulation of cell cycle processGO:00105642660.010
cell cell junction organizationGO:0045216690.010
neurological system processGO:00508771630.010
negative regulation of cellular protein catabolic processGO:1903363380.010

MLL3 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.016
central nervous system diseaseDOID:3311860.016
disease of cellular proliferationDOID:145661740.014
hematopoietic system diseaseDOID:741000.013
immune system diseaseDOID:29141550.013
organ system cancerDOID:00506861640.010
cancerDOID:1621670.010