Homo sapiens

146 known processes

MLL5

myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)

(Aliases: FLJ14026,MGC70452,FLJ10078,HDCMC04P,KMT2E)

MLL5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of cellular amine metabolic processGO:003324070.395
regulation of cellular amino acid metabolic processGO:000652160.309
cellular amine metabolic processGO:0044106410.300
histone modificationGO:00165702510.297
chromatin modificationGO:00165682980.256
chromatin organizationGO:00063253510.228
regulation of cellular ketone metabolic processGO:0010565500.220
regulation of cellular amine metabolic processGO:0033238110.210
positive regulation of cellular amino acid metabolic processGO:004576430.200
cellular amino acid metabolic processGO:00065201160.195
cellular ketone metabolic processGO:0042180800.188
protein modification by small protein conjugationGO:00324463420.182
amine metabolic processGO:0009308440.182
covalent chromatin modificationGO:00165692540.165
protein ubiquitinationGO:00165673140.157
regulation of cell differentiationGO:00455953930.139
methylationGO:00322591060.121
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.082
positive regulation of catabolic processGO:00098963100.081
histone lysine methylationGO:0034968500.077
actin filament based processGO:00300292240.076
hemopoiesisGO:00300971800.076
regulation of cellular response to stressGO:00801352440.069
small gtpase mediated signal transductionGO:0007264780.066
regulation of mapk cascadeGO:00434082620.065
negative regulation of catalytic activityGO:00430863350.062
ribonucleoside triphosphate catabolic processGO:00092033910.061
ras protein signal transductionGO:0007265730.061
negative regulation of cellular protein metabolic processGO:00322693530.060
negative regulation of multicellular organismal processGO:00512413170.058
positive regulation of organelle organizationGO:00106381950.057
determination of adult lifespanGO:000834020.055
post embryonic developmentGO:000979120.055
signal transduction by phosphorylationGO:00230142970.054
circulatory system developmentGO:00723592620.053
positive regulation of cellular component organizationGO:00511303760.050
hematopoietic or lymphoid organ developmentGO:00485341860.048
immune responseGO:00069553070.047
cellular response to endogenous stimulusGO:00714953360.047
positive regulation of chromosome organizationGO:2001252410.047
positive regulation of cellular catabolic processGO:00313312840.047
peptidyl lysine modificationGO:00182051440.045
macromolecule methylationGO:0043414970.043
peptidyl lysine acetylationGO:00183941010.043
negative regulation of protein metabolic processGO:00512483910.042
oxidation reduction processGO:00551143960.040
regulation of immune responseGO:00507762010.040
regulation of cell cycleGO:00517263930.040
negative regulation of protein modification processGO:00314002000.039
cellular macromolecule catabolic processGO:00442653800.038
protein acetylationGO:00064731160.037
response to organic cyclic compoundGO:00140702040.037
regulation of cell divisionGO:00513021160.036
myeloid cell differentiationGO:00300991170.036
mapk cascadeGO:00001652880.036
cellular macromolecular complex assemblyGO:00346223240.036
ribonucleotide catabolic processGO:00092614050.035
leukocyte activationGO:00453211640.035
Mouse
behaviorGO:00076101120.035
negative regulation of cellular amine metabolic processGO:003323930.035
regulation of chromosome organizationGO:00330441030.035
cardiovascular system developmentGO:00723582620.034
purine nucleoside triphosphate metabolic processGO:00091444120.034
lymphocyte activationGO:00466491330.033
regulation of cell cycle processGO:00105642660.033
negative regulation of cell differentiationGO:00455961710.033
ribonucleoside triphosphate metabolic processGO:00091994120.032
proteolysis involved in cellular protein catabolic processGO:00516032440.031
histone methylationGO:0016571600.031
guanosine containing compound metabolic processGO:19010682440.031
cytokine productionGO:00018162470.031
system processGO:00030083490.031
purine nucleoside triphosphate catabolic processGO:00091463920.030
motor neuron axon guidanceGO:000804520.030
ubiquitin dependent protein catabolic processGO:00065112060.030
negative regulation of phosphate metabolic processGO:00459362670.030
purine ribonucleoside triphosphate catabolic processGO:00092073910.030
nucleoside catabolic processGO:00091644080.030
nucleotide catabolic processGO:00091664080.029
actin cytoskeleton organizationGO:00300362070.029
secretion by cellGO:00329402260.029
oogenesisGO:004847720.029
neurological system processGO:00508771630.029
ribonucleoside catabolic processGO:00424544060.029
positive regulation of immune responseGO:00507781590.029
purine ribonucleoside triphosphate metabolic processGO:00092054110.029
protein catabolic processGO:00301633250.028
organ morphogenesisGO:00098871470.028
negative regulation of phosphorylationGO:00423261740.028
compound eye developmentGO:004874910.028
regulation of histone modificationGO:0031056470.028
hematopoietic progenitor cell differentiationGO:0002244380.028
cellular response to organic cyclic compoundGO:00714071270.028
protein deacylationGO:0035601390.027
multicellular organismal agingGO:001025930.027
nucleoside triphosphate metabolic processGO:00091414220.027
cell morphogenesisGO:00009022960.027
positive regulation of cell proliferationGO:00082843010.026
regulation of small gtpase mediated signal transductionGO:00510561560.026
anatomical structure formation involved in morphogenesisGO:00486462840.026
gtp metabolic processGO:00460392390.026
negative regulation of cellular component organizationGO:00511292350.026
purine nucleotide catabolic processGO:00061954050.026
glycosyl compound catabolic processGO:19016584130.026
regulation of cellular component biogenesisGO:00440872810.026
regulation of cytoskeleton organizationGO:00514931770.025
female gamete generationGO:000729220.025
positive regulation of immune system processGO:00026842830.025
gtp catabolic processGO:00061842370.025
guanosine containing compound catabolic processGO:19010692390.025
regulation of gtpase activityGO:00430871800.025
positive regulation of purine nucleotide catabolic processGO:00331231850.025
regulation of purine nucleotide metabolic processGO:19005422640.024
embryonic camera type eye developmentGO:003107620.024
regulation of protein catabolic processGO:00421761550.024
neuromuscular junction developmentGO:000752830.024
positive regulation of nucleoside metabolic processGO:00459791860.023
histone h3 k9 modificationGO:0061647110.023
cellular response to dna damage stimulusGO:00069743790.023
sensory perception of soundGO:0007605370.023
regulation of proteasomal protein catabolic processGO:0061136870.023
regulation of chromatin modificationGO:1903308510.023
purine containing compound catabolic processGO:00725234110.022
forelimb morphogenesisGO:003513640.022
regulation of heart growthGO:006042040.022
positive regulation of phosphorylationGO:00423273940.022
nucleoside phosphate catabolic processGO:19012924120.022
blastoderm segmentationGO:000735020.022
lipid metabolic processGO:00066293810.022
sensory perceptionGO:00076001030.022
regulation of mononuclear cell proliferationGO:0032944650.022
regulation of purine nucleotide catabolic processGO:00331212050.022
rna processingGO:00063962550.022
cell divisionGO:00513011680.022
nucleoside triphosphate catabolic processGO:00091433940.022
regulation of secretion by cellGO:19035301770.022
defense responseGO:00069523150.022
response to hormoneGO:00097251750.021
histone deacetylationGO:0016575320.021
regulation of protein transportGO:00512232130.021
response to biotic stimulusGO:00096072760.021
metal ion transportGO:00300012720.021
chemotaxisGO:00069351570.021
positive regulation of gtpase activityGO:00435471660.021
negative regulation of phosphorus metabolic processGO:00105632670.021
neurogenesisGO:00220081690.021
segmentationGO:003528240.021
rho protein signal transductionGO:0007266260.021
reproductive processGO:00224141060.021
positive regulation of purine nucleotide metabolic processGO:19005442270.021
mitotic nuclear divisionGO:00070671190.021
regulation of anatomical structure morphogenesisGO:00226032860.021
protein alkylationGO:0008213740.020
protein methylationGO:0006479740.020
purine nucleoside catabolic processGO:00061523980.020
cell developmentGO:00484683280.020
positive regulation of nucleotide catabolic processGO:00308131850.020
dephosphorylationGO:00163112090.020
regulation of nucleotide metabolic processGO:00061402690.020
secretionGO:00469032540.020
regulation of nucleoside metabolic processGO:00091182090.020
purine ribonucleoside catabolic processGO:00461303980.019
response to other organismGO:00517072610.019
mitotic cell cycleGO:00002783260.019
purine ribonucleotide catabolic processGO:00091544040.019
protein polyubiquitinationGO:00002091100.019
nervous system developmentGO:00073992930.019
regulation of secretionGO:00510461940.019
histone acetylationGO:0016573930.019
embryonic placenta developmentGO:000189210.019
rna catabolic processGO:0006401710.019
modification dependent protein catabolic processGO:00199412090.019
immune response regulating signaling pathwayGO:0002764970.019
tube developmentGO:00352951250.019
negative regulation of cellular amino acid metabolic processGO:004576320.018
negative regulation of programmed cell deathGO:00430693210.018
regulation of synaptic plasticityGO:004816730.018
protein deacetylationGO:0006476380.018
modification dependent macromolecule catabolic processGO:00436322120.018
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.018
cellular component morphogenesisGO:00329893140.018
regulation of cell activationGO:00508651250.018
peptidyl lysine methylationGO:0018022370.018
regulation of transferase activityGO:00513383550.018
regulation of neurotransmitter secretionGO:004692830.017
intracellular receptor signaling pathwayGO:00305221040.017
positive regulation of protein phosphorylationGO:00019343130.017
regulation of immune effector processGO:0002697910.017
mrna metabolic processGO:00160711750.017
dna templated transcription initiationGO:0006352350.017
cellular response to lipidGO:00713961270.017
response to abiotic stimulusGO:00096283360.017
cell projection organizationGO:00300302520.017
regulation of proteolysisGO:00301622930.017
epithelial cell differentiationGO:00308551410.017
negative regulation of intracellular signal transductionGO:19025321830.017
protein acylationGO:00435431380.017
protein maturationGO:00516042330.017
gene silencingGO:0016458490.017
positive regulation of transferase activityGO:00513472270.017
b cell activationGO:0042113330.016
regulation of leukocyte activationGO:00026941150.016
epithelium developmentGO:00604292270.016
growthGO:00400072020.016
myeloid leukocyte differentiationGO:0002573600.016
regulation of ras protein signal transductionGO:00465781550.016
response to external biotic stimulusGO:00432072610.016
regulation of response to external stimulusGO:00321012220.016
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.016
agingGO:0007568660.016
response to woundingGO:00096111680.016
mitotic cell cycle processGO:19030472860.016
positive regulation of histone modificationGO:0031058290.015
positive regulation of nucleotide metabolic processGO:00459812300.015
cellular response to glucocorticoid stimulusGO:007138540.015
heart developmentGO:0007507950.015
immune response activating signal transductionGO:0002757900.015
multicellular organismal reproductive processGO:0048609400.015
single organism reproductive processGO:0044702980.015
immune effector processGO:00022521590.015
Mouse
positive regulation of mapk cascadeGO:00434101900.015
positive regulation of transportGO:00510503360.015
cell projection morphogenesisGO:00488581290.015
cation transportGO:00068123310.015
positive regulation of cell differentiationGO:00455972110.015
immune system developmentGO:00025201950.014
neuron projection developmentGO:00311751060.014
protein processingGO:00164852260.014
regulation of multi organism processGO:00439001570.014
regulation of protein kinase activityGO:00458592890.014
regulation of gtp catabolic processGO:00331241800.014
innate immune responseGO:00450871780.014
regulation of stress activated protein kinase signaling cascadeGO:0070302850.014
spinal cord developmentGO:002151040.014
positive regulation of hydrolase activityGO:00513453310.014
purine ribonucleoside metabolic processGO:00461284370.014
negative regulation of developmental processGO:00510932470.014
dna replicationGO:00062601160.014
lymphocyte proliferationGO:0046651700.014
negative regulation of synaptic transmissionGO:005080520.014
t cell activationGO:0042110990.014
negative regulation of cell deathGO:00605483450.014
neurotransmitter secretionGO:000726940.014
negative regulation of hydrolase activityGO:00513461820.013
negative regulation of secretion by cellGO:1903531520.013
leukocyte differentiationGO:0002521980.013
regulation of defense responseGO:00313471540.013
response to oxygen containing compoundGO:19017003690.013
multi organism reproductive processGO:0044703540.013
cellular protein complex assemblyGO:00436231880.013
embryonic eye morphogenesisGO:004804820.013
regulation of nucleotide catabolic processGO:00308112050.013
myosin filament organizationGO:003103320.013
sensory perception of mechanical stimulusGO:0050954370.013
regulation of chromatin organizationGO:1902275560.013
peptidyl tyrosine phosphorylationGO:00181081700.013
negative regulation of organelle organizationGO:00106391260.013
muscle structure developmentGO:0061061980.013
negative regulation of protein maturationGO:19033181420.013
negative regulation of t cell cytokine productionGO:000272540.013
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.013
negative regulation of transportGO:00510511760.013
response to radiationGO:00093141510.013
negative regulation of immune system processGO:00026831360.012
regulation of protein maturationGO:19033171500.012
organelle fissionGO:00482851490.012
positive regulation of chromatin modificationGO:1903310300.012
cytokinesisGO:0000910960.012
negative regulation of apoptotic processGO:00430663160.012
regulation of protein serine threonine kinase activityGO:00719001790.012
striated muscle myosin thick filament assemblyGO:007168820.012
actin filament organizationGO:00070151280.012
cell morphogenesis involved in differentiationGO:00009041440.012
positive regulation of protein kinase activityGO:00458601900.012
regulation of cell morphogenesisGO:00226041530.012
reactive oxygen species biosynthetic processGO:190340940.012
biological adhesionGO:00226103310.012
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.012
regulation of protein stabilityGO:0031647870.012
negative regulation of catabolic processGO:00098951040.012
proteasomal protein catabolic processGO:00104981760.012
mrna catabolic processGO:0006402560.012
positive regulation of protein catabolic processGO:0045732750.012
negative regulation of mapk cascadeGO:0043409560.012
macromolecule deacylationGO:0098732410.012
cell part morphogenesisGO:00329901370.012
cellular polysaccharide catabolic processGO:004424740.012
maintenance of locationGO:00512351120.012
memoryGO:000761330.012
organelle assemblyGO:00709251760.012
locomotory behaviorGO:000762610.012
i kappab kinase nf kappab signalingGO:00072491660.012
negative regulation of secretionGO:0051048580.012
regulation of ras gtpase activityGO:00323181280.011
regulation of canonical wnt signaling pathwayGO:0060828880.011
negative regulation of proteolysisGO:00458611320.011
cellular response to oxygen containing compoundGO:19017012760.011
embryonic viscerocranium morphogenesisGO:004870310.011
salivary gland morphogenesisGO:000743540.011
response to nitrogen compoundGO:19016981840.011
morphogenesis of embryonic epitheliumGO:001633140.011
positive regulation of apoptotic processGO:00430652460.011
cellular carbohydrate metabolic processGO:0044262840.011
head developmentGO:00603221080.011
internal peptidyl lysine acetylationGO:0018393970.011
sister chromatid cohesionGO:0007062240.011
protein oligomerizationGO:00512591730.011
cell activationGO:00017752130.011
Mouse
positive regulation of gtp catabolic processGO:00331261660.011
chromosome segregationGO:00070591140.011
cellular protein catabolic processGO:00442572610.011
blood vessel morphogenesisGO:00485141620.011
protein modification by small protein removalGO:0070646920.011
embryonic epithelial tube formationGO:000183840.011
cellular response to nitrogen compoundGO:19016991440.011
single organism carbohydrate metabolic processGO:00447231930.011
regulation of sequence specific dna binding transcription factor activityGO:00510902110.011
peptidyl lysine trimethylationGO:0018023100.011
angiogenesisGO:00015251470.011
mrna processingGO:00063971330.011
regulation of apoptotic signaling pathwayGO:20012331750.011
nucleocytoplasmic transportGO:00069131760.011
regulation of synaptic vesicle exocytosisGO:200030020.010
antigen receptor mediated signaling pathwayGO:0050851380.010
viral transcriptionGO:0019083350.010
ion transmembrane transportGO:00342203380.010
peptidyl serine modificationGO:00182091060.010
embryonic camera type eye morphogenesisGO:004859620.010
regulation of innate immune responseGO:0045088970.010
regulation of protein processingGO:00706131500.010
negative regulation of defense responseGO:0031348470.010
regulation of cytokine productionGO:00018172320.010
transmembrane transportGO:00550853990.010
regulation of lymphocyte proliferationGO:0050670640.010
inner ear morphogenesisGO:004247240.010
interspecies interaction between organismsGO:00444191560.010
regulation of peptidyl tyrosine phosphorylationGO:00507301080.010
lymphocyte differentiationGO:0030098350.010
regulation of map kinase activityGO:00434051080.010
positive regulation of proteolysisGO:00458621420.010

MLL5 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.012
sensory system diseaseDOID:00501552030.012