Homo sapiens

0 known processes

ALAS1

aminolevulinate, delta-, synthase 1

(Aliases: ALASH,ALAS3,ALAS,MIG4)

ALAS1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
multicellular organismal agingGO:001025930.625
determination of adult lifespanGO:000834020.544
response to oxygen containing compoundGO:19017003690.499
oxidation reduction processGO:00551143960.476
post embryonic developmentGO:000979120.473
regulation of cell differentiationGO:00455953930.396
lipid modificationGO:0030258840.313
biological adhesionGO:00226103310.299
regulation of synaptic plasticityGO:004816730.298
cell adhesionGO:00071553250.277
carbohydrate metabolic processGO:00059752070.262
cell matrix adhesionGO:0007160850.253
cellular lipid metabolic processGO:00442553030.240
regulation of transferase activityGO:00513383550.214
response to woundingGO:00096111680.210
cerebral cortex radially oriented cell migrationGO:002179910.202
negative regulation of cell deathGO:00605483450.190
female gamete generationGO:000729220.188
ribonucleoside triphosphate metabolic processGO:00091994120.184
secretionGO:00469032540.179
neuromuscular junction developmentGO:000752830.172
organic hydroxy compound metabolic processGO:19016151470.171
blood coagulationGO:0007596760.168
nucleoside triphosphate metabolic processGO:00091414220.154
positive regulation of phosphorylationGO:00423273940.154
purine ribonucleoside triphosphate metabolic processGO:00092054110.148
coagulationGO:0050817780.146
nucleoside catabolic processGO:00091644080.145
organophosphate catabolic processGO:00464344300.142
negative regulation of axon extensionGO:003051720.140
ribonucleoside catabolic processGO:00424544060.140
regulation of body fluid levelsGO:0050878990.131
positive regulation of protein phosphorylationGO:00019343130.131
negative regulation of programmed cell deathGO:00430693210.129
cell substrate adhesionGO:00315891320.128
positive regulation of programmed cell deathGO:00430682490.128
reactive oxygen species metabolic processGO:0072593750.121
purine ribonucleoside catabolic processGO:00461303980.121
glycerolipid metabolic processGO:00464861070.119
cranial nerve developmentGO:002154540.118
regulation of locomotionGO:00400123290.117
positive regulation of protein kinase activityGO:00458601900.117
visual learningGO:000854210.114
apoptotic signaling pathwayGO:00971902680.113
optic nerve developmentGO:002155420.110
ion homeostasisGO:00508012300.108
response to organonitrogen compoundGO:00102431560.106
regulation of protein kinase activityGO:00458592890.105
monocarboxylic acid metabolic processGO:00327871850.101
purine nucleoside triphosphate metabolic processGO:00091444120.100
regulation of anatomical structure morphogenesisGO:00226032860.099
mitotic cell cycleGO:00002783260.098
motor neuron axon guidanceGO:000804520.098
nerve developmentGO:002167540.097
purine ribonucleoside triphosphate catabolic processGO:00092073910.096
embryo developmentGO:00097901230.095
ribonucleoside triphosphate catabolic processGO:00092033910.094
regulation of kinase activityGO:00435493140.094
platelet activationGO:0030168440.094
actin cytoskeleton organizationGO:00300362070.092
wound healingGO:00420601150.092
lipid metabolic processGO:00066293810.091
regulation of reactive oxygen species metabolic processGO:2000377410.091
nervous system developmentGO:00073992930.091
cerebellum developmentGO:002154920.090
regulation of cell motilityGO:20001452990.089
positive regulation of apoptotic processGO:00430652460.089
enzyme linked receptor protein signaling pathwayGO:00071673030.087
response to abiotic stimulusGO:00096283360.085
negative regulation of cell differentiationGO:00455961710.085
purine nucleoside catabolic processGO:00061523980.085
lipid biosynthetic processGO:00086101770.083
positive regulation of developmental processGO:00510943140.082
phosphatidylinositol 3 phosphate biosynthetic processGO:003609230.081
cellular component morphogenesisGO:00329893140.080
positive regulation of cell deathGO:00109422630.079
secretion by cellGO:00329402260.078
negative regulation of transportGO:00510511760.078
cellular amino acid metabolic processGO:00065201160.077
cellular cation homeostasisGO:00300031630.076
adult locomotory behaviorGO:000834410.076
regulation of cell cycleGO:00517263930.074
oogenesisGO:004847720.074
actin filament based processGO:00300292240.074
cellular chemical homeostasisGO:00550821800.073
regulation of cell migrationGO:00303342890.073
cellular response to oxygen containing compoundGO:19017012760.073
immune responseGO:00069553070.073
response to nitrogen compoundGO:19016981840.072
chromatin organizationGO:00063253510.071
cation homeostasisGO:00550801890.071
cerebral cortex cell migrationGO:002179530.071
regulation of cellular component sizeGO:0032535820.071
cellular homeostasisGO:00197251960.069
regulation of cell matrix adhesionGO:0001952420.068
hindbrain developmentGO:003090230.068
taxisGO:00423301570.068
regulation of dendrite developmentGO:0050773180.068
synaptic transmissionGO:0007268610.068
negative regulation of cellular protein metabolic processGO:00322693530.068
small molecule catabolic processGO:0044282920.067
regulation of anatomical structure sizeGO:00900661010.066
chemical homeostasisGO:00488783060.065
purine ribonucleoside metabolic processGO:00461284370.065
purine containing compound catabolic processGO:00725234110.063
growthGO:00400072020.062
hemostasisGO:0007599760.062
exocytosisGO:0006887710.061
guanosine containing compound metabolic processGO:19010682440.061
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.061
cell morphogenesisGO:00009022960.060
ion transmembrane transportGO:00342203380.060
sensory perception of painGO:001923340.060
ribonucleotide catabolic processGO:00092614050.060
neuroblast proliferationGO:000740540.059
fatty acid metabolic processGO:00066311150.059
cellular response to nitrogen compoundGO:19016991440.059
cell cell signalingGO:00072671550.059
chemotaxisGO:00069351570.058
purine nucleotide catabolic processGO:00061954050.058
response to organic cyclic compoundGO:00140702040.058
jak stat cascadeGO:0007259460.057
regulation of nervous system developmentGO:0051960880.057
response to metal ionGO:0010038840.057
cell activationGO:00017752130.057
negative regulation of protein metabolic processGO:00512483910.057
nucleotide catabolic processGO:00091664080.056
cranial nerve morphogenesisGO:002160210.056
protein maturationGO:00516042330.056
organophosphate biosynthetic processGO:00904071630.055
negative regulation of cellular component organizationGO:00511292350.054
glycerolipid biosynthetic processGO:0045017510.054
sulfur compound metabolic processGO:00067901010.053
glycosyl compound catabolic processGO:19016584130.053
response to biotic stimulusGO:00096072760.053
regulation of neuronal synaptic plasticityGO:004816810.053
nucleoside triphosphate catabolic processGO:00091433940.052
ras protein signal transductionGO:0007265730.052
neuron developmentGO:00486661130.052
positive regulation of protein targeting to membraneGO:009031480.051
metal ion transportGO:00300012720.051
regulation of neurogenesisGO:0050767820.051
regulation of cellular amino acid metabolic processGO:000652160.050
cell part morphogenesisGO:00329901370.050
regulation of cellular ketone metabolic processGO:0010565500.050
response to nutrient levelsGO:0031667810.049
generation of precursor metabolites and energyGO:0006091680.049
protein targetingGO:00066051870.049
cranial nerve formationGO:002160310.049
protein modification by small protein conjugationGO:00324463420.048
carboxylic acid biosynthetic processGO:0046394970.048
neuron differentiationGO:00301821380.048
neurogenesisGO:00220081690.047
single organism carbohydrate metabolic processGO:00447231930.047
response to radiationGO:00093141510.047
generation of neuronsGO:00486991520.047
regulation of cell developmentGO:00602841610.046
regulation of proteolysisGO:00301622930.046
anatomical structure formation involved in morphogenesisGO:00486462840.046
small gtpase mediated signal transductionGO:0007264780.046
tricarboxylic acid metabolic processGO:007235040.046
system processGO:00030083490.046
cellular ion homeostasisGO:00068731680.046
cellular ketone metabolic processGO:0042180800.046
synaptic vesicle recyclingGO:003646530.045
protein processingGO:00164852260.045
protein ubiquitinationGO:00165673140.045
protein autophosphorylationGO:00467771230.045
associative learningGO:000830610.044
regulation of protein serine threonine kinase activityGO:00719001790.044
cerebral cortex radial glia guided migrationGO:002180110.043
negative regulation of developmental processGO:00510932470.043
cellular response to extracellular stimulusGO:0031668720.042
cell projection morphogenesisGO:00488581290.042
cellular response to dna damage stimulusGO:00069743790.042
regulation of mitotic cell cycleGO:00073461890.042
response to extracellular stimulusGO:0009991850.041
regulation of cellular amine metabolic processGO:0033238110.041
regulation of protein processingGO:00706131500.040
cofactor metabolic processGO:0051186870.040
single organism cellular localizationGO:19025803320.040
organic acid catabolic processGO:0016054710.040
regulation of nucleotide catabolic processGO:00308112050.040
cellular amine metabolic processGO:0044106410.039
negative regulation of axonogenesisGO:005077140.039
regulation of cell projection organizationGO:00313441070.038
regulation of cellular component movementGO:00512703340.038
purine nucleoside triphosphate catabolic processGO:00091463920.038
regulation of cell substrate adhesionGO:0010810680.038
inorganic cation transmembrane transportGO:00986621940.038
chromatin modificationGO:00165682980.038
segmentationGO:003528240.037
innate immune responseGO:00450871780.037
neuron projection developmentGO:00311751060.037
negative regulation of phosphorylationGO:00423261740.037
limbic system developmentGO:002176130.037
receptor metabolic processGO:0043112810.037
positive regulation of organ growthGO:004662220.037
regulation of growthGO:00400081650.037
defense responseGO:00069523150.037
tissue regenerationGO:004224630.037
regulation of neuron projection developmentGO:0010975570.036
carboxylic acid catabolic processGO:0046395710.036
response to light stimulusGO:0009416870.036
positive regulation of cellular amino acid metabolic processGO:004576430.036
negative regulation of catalytic activityGO:00430863350.036
intracellular protein transportGO:00068862700.036
organonitrogen compound biosynthetic processGO:19015662000.036
tissue morphogenesisGO:0048729960.036
nuclear exportGO:0051168690.036
gtp metabolic processGO:00460392390.035
negative regulation of phosphorus metabolic processGO:00105632670.035
response to inorganic substanceGO:00100351270.035
regulation of chemotaxisGO:0050920740.035
intrinsic apoptotic signaling pathwayGO:00971931270.035
visual behaviorGO:000763220.034
atp metabolic processGO:00460341760.034
positive regulation of exocytosisGO:0045921350.034
asymmetric stem cell divisionGO:009872210.034
positive regulation of transportGO:00510503360.034
regulation of response to external stimulusGO:00321012220.034
cellular calcium ion homeostasisGO:00068741170.034
regulation of vesicle mediated transportGO:00606271300.034
positive regulation of cell sizeGO:004579330.034
neurological system processGO:00508771630.033
vesicle mediated transportGO:00161923710.033
neuronal stem cell divisionGO:003644510.033
apoptotic mitochondrial changesGO:0008637570.033
locomotory behaviorGO:000762610.032
regulation of protein modification by small protein conjugation or removalGO:19033201070.032
cellular metal ion homeostasisGO:00068751460.032
cation transmembrane transportGO:00986552380.032
energy derivation by oxidation of organic compoundsGO:0015980430.032
embryonic retina morphogenesis in camera type eyeGO:006005910.032
nucleoside monophosphate metabolic processGO:00091231910.032
organelle localizationGO:0051640840.032
cellular response to nutrient levelsGO:0031669690.031
cytoplasmic transportGO:00164823790.031
transmembrane transportGO:00550853990.031
coenzyme metabolic processGO:0006732650.031
glycerophospholipid metabolic processGO:0006650840.031
positive regulation of kinase activityGO:00336742040.031
synaptic vesicle endocytosisGO:004848820.031
metal ion homeostasisGO:00550651690.031
lipid catabolic processGO:0016042840.030
histone modificationGO:00165702510.030
negative regulation of phosphate metabolic processGO:00459362670.030
epithelium developmentGO:00604292270.030
metencephalon developmentGO:002203720.030
regulation of mapk cascadeGO:00434082620.030
negative regulation of proteolysisGO:00458611320.030
cellular response to hormone stimulusGO:00328701250.030
organ morphogenesisGO:00098871470.030
cation transportGO:00068123310.030
amine metabolic processGO:0009308440.030
posttranscriptional regulation of gene expressionGO:00106082130.029
cofactor biosynthetic processGO:0051188310.029
regulation of apoptotic signaling pathwayGO:20012331750.029
response to hormoneGO:00097251750.029
neuron remodelingGO:001632220.029
regulation of synapse structural plasticityGO:005182320.029
protein targeting to membraneGO:0006612420.029
positive regulation of immune system processGO:00026842830.028
endocytosisGO:00068971590.028
cell projection organizationGO:00300302520.028
regulation of bindingGO:00510981110.028
regulation of protein transportGO:00512232130.028
response to campGO:0051591250.028
mitochondrion organizationGO:00070051560.028
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.028
agingGO:0007568660.028
regulation of cell adhesionGO:00301551660.028
response to cytokineGO:00340972320.027
cardiovascular system developmentGO:00723582620.027
purine ribonucleoside monophosphate metabolic processGO:00091671860.027
epithelial cell differentiationGO:00308551410.027
regulation of nucleocytoplasmic transportGO:0046822980.027
retina layer formationGO:001084230.027
inorganic ion transmembrane transportGO:00986602310.027
covalent chromatin modificationGO:00165692540.027
cellular response to endogenous stimulusGO:00714953360.026
regulation of transporter activityGO:0032409820.026
regenerationGO:003109940.026
regulation of purine nucleotide catabolic processGO:00331212050.026
positive regulation of cellular catabolic processGO:00313312840.026
regulation of transmembrane transporter activityGO:0022898740.026
regulation of translationGO:0006417890.025
single organismal cell cell adhesionGO:00163371480.025
cellular response to cytokine stimulusGO:00713451810.025
small molecule biosynthetic processGO:00442831570.025
cellular response to starvationGO:0009267580.025
carbohydrate biosynthetic processGO:0016051420.025
membrane organizationGO:00610242920.025
atp catabolic processGO:00062001570.025
regulation of exocytosisGO:0017157460.025
regulation of purine nucleotide metabolic processGO:19005422640.025
regulation of protein localizationGO:00328802960.025
cellular response to organonitrogen compoundGO:00714171240.024
regulation of intracellular transportGO:00323861950.024
negative regulation of cellular catabolic processGO:0031330830.024
calcium ion importGO:0070509230.024
regulation of gtpase activityGO:00430871800.024
response to oxidative stressGO:00069791210.024
dicarboxylic acid metabolic processGO:0043648290.024
negative regulation of protein modification processGO:00314002000.024
negative regulation of multicellular organismal processGO:00512413170.024
negative regulation of cell cycleGO:00457861930.023
translationGO:00064121320.023
lipid oxidationGO:0034440330.023
regulation of behaviorGO:0050795820.023
dendritic spine morphogenesisGO:006099730.023
alcohol metabolic processGO:00060661140.023
negative regulation of protein processingGO:00109551420.023
immune effector processGO:00022521590.023
negative regulation of intracellular signal transductionGO:19025321830.023
phosphatidylinositol metabolic processGO:0046488530.023
positive regulation of secretion by cellGO:19035321080.023
single organism cell adhesionGO:00986021790.023
response to endoplasmic reticulum stressGO:0034976490.022
purine nucleoside monophosphate metabolic processGO:00091261860.022
cellular carbohydrate biosynthetic processGO:0034637210.022
ribonucleoside monophosphate metabolic processGO:00091611870.022
regulation of ion transmembrane transporter activityGO:0032412720.022
regulation of secretionGO:00510461940.022
cellular carbohydrate metabolic processGO:0044262840.022
regulation of cytoplasmic transportGO:19036491490.022
regulation of protein ubiquitinationGO:0031396950.022
hippocampus developmentGO:002176610.021
cell developmentGO:00484683280.021
peripheral nervous system developmentGO:000742220.021
response to cocaineGO:004222010.021
carbohydrate derivative biosynthetic processGO:19011372070.021
circulatory system developmentGO:00723592620.021
microtubule based processGO:00070172100.021
nucleoside phosphate catabolic processGO:19012924120.021
tricarboxylic acid cycleGO:000609940.020
single organism membrane organizationGO:00448022680.020
negative regulation of catabolic processGO:00098951040.020
protein localization to synapseGO:003541820.020
response to drugGO:0042493810.020
positive regulation of transferase activityGO:00513472270.020
receptor catabolic processGO:0032801110.020
regulation of cellular response to stressGO:00801352440.020
positive regulation of cellular amine metabolic processGO:003324070.020
establishment of protein localization to membraneGO:00901501210.020
cellular lipid catabolic processGO:0044242650.020
nitrogen compound transportGO:00717051910.020
anterior posterior axis specificationGO:000994820.020
neuroblast divisionGO:005505710.020
mitotic cell cycle processGO:19030472860.020
somatic stem cell divisionGO:004810310.020
embryo development ending in birth or egg hatchingGO:0009792340.020
reproductionGO:0000003630.020
hydrogen transportGO:0006818230.019
regulation of immune responseGO:00507762010.019
regulation of stress activated protein kinase signaling cascadeGO:0070302850.019
regulation of intracellular protein transportGO:00331571230.019
regulation of protein maturationGO:19033171500.019
cell cycle g2 m phase transitionGO:0044839430.019
autophagyGO:0006914880.019
neutral lipid metabolic processGO:0006638270.019
stress activated protein kinase signaling cascadeGO:0031098940.019
embryonic morphogenesisGO:0048598850.019
nucleocytoplasmic transportGO:00069131760.019
positive regulation of protein serine threonine kinase activityGO:00719021190.019
negative regulation of intracellular transportGO:0032387600.019
phospholipid biosynthetic processGO:0008654440.019
reactive nitrogen species metabolic processGO:200105730.018
regulation of transmembrane transportGO:00347621390.018
regulation of synaptic transmissionGO:0050804110.018
cell type specific apoptotic processGO:00972851250.018
positive regulation of catabolic processGO:00098963100.018
glycoprotein metabolic processGO:00091001100.018
positive regulation of nucleoside metabolic processGO:00459791860.018
coenzyme biosynthetic processGO:0009108240.018
regulation of neuron differentiationGO:0045664700.018
regulation of jnk cascadeGO:0046328730.018
peptidyl threonine modificationGO:0018210450.018
lipid localizationGO:00108761060.018
cellular macromolecule catabolic processGO:00442653800.018
phospholipid metabolic processGO:0006644990.017
sensory perceptionGO:00076001030.017
head developmentGO:00603221080.017
regulation of nucleoside metabolic processGO:00091182090.017
response to lipidGO:00339932060.017
regulation of ion transportGO:00432691890.017
dendritic spine organizationGO:009706140.017
positive regulation of gtpase activityGO:00435471660.017
single organism reproductive processGO:0044702980.017
response to cadmium ionGO:0046686100.017
receptor mediated endocytosisGO:0006898840.017
negative regulation of organelle organizationGO:00106391260.017
central nervous system developmentGO:00074171230.017
brain developmentGO:0007420970.017
positive regulation of vascular endothelial growth factor signaling pathwayGO:190074830.017
somitogenesisGO:000175620.016
cellular polysaccharide metabolic processGO:0044264270.016
developmental growthGO:0048589480.016
cell morphogenesis involved in neuron differentiationGO:0048667440.016
regulation of protein targetingGO:1903533910.016
regulation of cellular component biogenesisGO:00440872810.016
acylglycerol metabolic processGO:0006639270.016
regulation of defense responseGO:00313471540.016
positive regulation of cell differentiationGO:00455972110.016
establishment of vesicle localizationGO:0051650230.016
cellular protein catabolic processGO:00442572610.016
regulation of cell morphogenesisGO:00226041530.016
glycerophospholipid biosynthetic processGO:0046474400.016
negative regulation of protein maturationGO:19033181420.016
phosphatidylinositol biosynthetic processGO:0006661250.016
nuclear transportGO:00511691790.016
regulation of endopeptidase activityGO:00525481700.015
positive regulation of cell proliferationGO:00082843010.015
negative regulation of protein kinase activityGO:0006469980.015
response to uvGO:0009411730.015
regulation of neurotransmitter secretionGO:004692830.015
salivary gland morphogenesisGO:000743540.015
regulation of cell cycle processGO:00105642660.015
protein catabolic processGO:00301633250.015
response to purine containing compoundGO:0014074400.015
proteoglycan catabolic processGO:003016730.015
steroid metabolic processGO:0008202940.015
inflammatory responseGO:0006954790.015
cell growthGO:00160491600.015
regulation of platelet aggregationGO:009033040.015
cognitionGO:0050890430.015
oxidoreduction coenzyme metabolic processGO:0006733190.015
neuron projection morphogenesisGO:0048812500.015
monosaccharide metabolic processGO:0005996740.014
dephosphorylationGO:00163112090.014
response to starvationGO:0042594590.014
negative regulation of locomotionGO:00400131180.014
response to lithium ionGO:001022620.014
regulation of anoikisGO:2000209190.014
negative regulation of protein phosphorylationGO:00019331400.014
long chain fatty acid metabolic processGO:0001676300.014
striated muscle myosin thick filament assemblyGO:007168820.014
myosin filament assemblyGO:003103420.014
dna damage checkpointGO:0000077680.014
negative regulation of immune system processGO:00026831360.014
response to fungusGO:000962040.014
negative regulation of cellular amine metabolic processGO:003323930.014
negative regulation of protein transportGO:0051224750.014
dicarboxylic acid biosynthetic processGO:004365040.014
cell divisionGO:00513011680.014
vasculature developmentGO:00019441810.014
defense response to other organismGO:00985421290.014
peptidyl threonine phosphorylationGO:0018107410.014
citrate metabolic processGO:000610120.014
organic acid biosynthetic processGO:0016053970.014
behaviorGO:00076101120.014
chromosome segregationGO:00070591140.014
guanosine containing compound catabolic processGO:19010692390.014
positive regulation of gtp catabolic processGO:00331261660.014
cilium organizationGO:0044782680.014
heart developmentGO:0007507950.014
cerebellar cortex developmentGO:002169510.014
spermatid differentiationGO:004851540.014
glycerol metabolic processGO:000607140.014
positive regulation of growthGO:0045927580.014
purine ribonucleotide catabolic processGO:00091544040.014
sulfur compound biosynthetic processGO:0044272380.013
aspartate metabolic processGO:000653140.013
positive regulation of cell cycleGO:00457871400.013
behavioral response to cocaineGO:004814810.013
response to calcium ionGO:0051592460.013
nucleotide biosynthetic processGO:00091651090.013
response to tumor necrosis factorGO:0034612760.013
platelet aggregationGO:0070527320.013
purine nucleoside monophosphate catabolic processGO:00091281580.013
negative regulation of cell proliferationGO:00082852280.013
regulation of autophagyGO:0010506520.013
positive regulation of apoptotic signaling pathwayGO:2001235700.013
positive regulation of intracellular transportGO:00323881040.013
phosphatidylinositol phosphorylationGO:0046854240.013
gtp catabolic processGO:00061842370.013
response to peptide hormoneGO:0043434610.013
positive regulation of nucleotide catabolic processGO:00308131850.013
cell proliferation in forebrainGO:002184610.013
response to bacteriumGO:00096171440.013
reproductive processGO:00224141060.013

ALAS1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:00501552030.051
nervous system diseaseDOID:8634310.051
central nervous system diseaseDOID:3311860.036
immune system diseaseDOID:29141550.032
cancerDOID:1621670.027
disease of cellular proliferationDOID:145661740.027
organ system cancerDOID:00506861640.027
eye and adnexa diseaseDOID:14921500.026
disease of metabolismDOID:00146672950.021
eye diseaseDOID:56141490.018
connective tissue diseaseDOID:651090.015
bone diseaseDOID:0080001880.015
musculoskeletal system diseaseDOID:172230.015