Homo sapiens

0 known processes

PPP1R13L

protein phosphatase 1, regulatory (inhibitor) subunit 13 like

(Aliases: IASPP,RAI4,NKIP1,RAI)

PPP1R13L biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
small gtpase mediated signal transductionGO:0007264780.143
regulation of cellular component movementGO:00512703340.141
post embryonic developmentGO:000979120.121
Mouse
purine nucleoside catabolic processGO:00061523980.103
regulation of cell differentiationGO:00455953930.101
cellular response to growth factor stimulusGO:00713631970.098
amine metabolic processGO:0009308440.097
skin developmentGO:0043588760.096
regulation of nucleoside metabolic processGO:00091182090.094
biological adhesionGO:00226103310.091
cellular amino acid metabolic processGO:00065201160.090
purine nucleoside triphosphate catabolic processGO:00091463920.088
cellular amine metabolic processGO:0044106410.088
enzyme linked receptor protein signaling pathwayGO:00071673030.087
purine containing compound catabolic processGO:00725234110.086
nucleoside catabolic processGO:00091644080.085
system processGO:00030083490.085
Mouse
nucleoside triphosphate catabolic processGO:00091433940.085
regulation of cellular ketone metabolic processGO:0010565500.084
purine nucleoside triphosphate metabolic processGO:00091444120.082
ribonucleoside triphosphate catabolic processGO:00092033910.080
ribonucleoside triphosphate metabolic processGO:00091994120.080
ribonucleoside catabolic processGO:00424544060.080
ribonucleotide catabolic processGO:00092614050.079
regulation of cellular amino acid metabolic processGO:000652160.079
glycosyl compound catabolic processGO:19016584130.079
positive regulation of cellular amino acid metabolic processGO:004576430.078
regulation of cellular amine metabolic processGO:0033238110.078
positive regulation of hydrolase activityGO:00513453310.076
rho protein signal transductionGO:0007266260.076
cell adhesionGO:00071553250.074
regulation of cell migrationGO:00303342890.074
cellular response to endogenous stimulusGO:00714953360.073
regulation of cell adhesionGO:00301551660.072
nucleotide catabolic processGO:00091664080.072
membrane organizationGO:00610242920.072
response to abiotic stimulusGO:00096283360.072
epithelium developmentGO:00604292270.071
female gamete generationGO:000729220.070
purine ribonucleotide catabolic processGO:00091544040.069
regulation of cell cycleGO:00517263930.069
oogenesisGO:004847720.068
response to growth factorGO:00708482050.067
positive regulation of cellular component organizationGO:00511303760.067
purine ribonucleoside triphosphate catabolic processGO:00092073910.066
regulation of cell motilityGO:20001452990.065
regulation of cellular component biogenesisGO:00440872810.065
actin filament based processGO:00300292240.064
cell projection organizationGO:00300302520.064
nucleoside triphosphate metabolic processGO:00091414220.064
cellular component morphogenesisGO:00329893140.063
circulatory system developmentGO:00723592620.063
Mouse
purine nucleotide catabolic processGO:00061954050.062
nucleoside phosphate catabolic processGO:19012924120.062
negative regulation of developmental processGO:00510932470.062
regulation of sequence specific dna binding transcription factor activityGO:00510902110.062
ras protein signal transductionGO:0007265730.062
purine ribonucleoside triphosphate metabolic processGO:00092054110.061
regulation of locomotionGO:00400123290.061
regulation of cellular response to stressGO:00801352440.060
epidermis developmentGO:0008544590.059
purine ribonucleoside metabolic processGO:00461284370.059
gtp catabolic processGO:00061842370.059
positive regulation of developmental processGO:00510943140.058
negative regulation of catalytic activityGO:00430863350.058
endomembrane system organizationGO:00102561960.057
epidermis morphogenesisGO:004873030.057
purine ribonucleoside catabolic processGO:00461303980.057
anatomical structure formation involved in morphogenesisGO:00486462840.055
organ morphogenesisGO:00098871470.054
Mouse
regulation of anatomical structure morphogenesisGO:00226032860.054
regulation of cell developmentGO:00602841610.054
negative regulation of apoptotic processGO:00430663160.054
cellular ketone metabolic processGO:0042180800.053
single organism cell adhesionGO:00986021790.052
cardiovascular system developmentGO:00723582620.051
Mouse
segmentationGO:003528240.051
tissue morphogenesisGO:0048729960.051
single organism membrane organizationGO:00448022680.050
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.050
Mouse
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.050
negative regulation of multicellular organismal processGO:00512413170.050
positive regulation of cellular amine metabolic processGO:003324070.050
regulation of gtpase activityGO:00430871800.050
guanosine containing compound metabolic processGO:19010682440.050
cell developmentGO:00484683280.049
negative regulation of protein metabolic processGO:00512483910.049
protein catabolic processGO:00301633250.049
regulation of purine nucleotide catabolic processGO:00331212050.049
neuromuscular junction developmentGO:000752830.048
gtp metabolic processGO:00460392390.048
cellular response to dna damage stimulusGO:00069743790.047
vesicle mediated transportGO:00161923710.046
chemical homeostasisGO:00488783060.046
cell morphogenesisGO:00009022960.046
regulation of nucleotide catabolic processGO:00308112050.046
regulation of proteolysisGO:00301622930.046
positive regulation of catabolic processGO:00098963100.045
positive regulation of phosphorylationGO:00423273940.045
determination of adult lifespanGO:000834020.045
organophosphate catabolic processGO:00464344300.045
regulation of gtp catabolic processGO:00331241800.044
regulation of cytoskeleton organizationGO:00514931770.044
morphogenesis of embryonic epitheliumGO:001633140.044
negative regulation of cell deathGO:00605483450.044
growthGO:00400072020.043
Mouse
wnt signaling pathwayGO:00160551560.043
positive regulation of protein phosphorylationGO:00019343130.042
chemotaxisGO:00069351570.042
regulation of transferase activityGO:00513383550.042
single organism cellular localizationGO:19025803320.042
guanosine containing compound catabolic processGO:19010692390.042
taxisGO:00423301570.042
nervous system developmentGO:00073992930.042
angiogenesisGO:00015251470.041
positive regulation of cell differentiationGO:00455972110.041
histone modificationGO:00165702510.041
regulation of cell morphogenesis involved in differentiationGO:0010769830.041
positive regulation of locomotionGO:00400171860.041
transmembrane transportGO:00550853990.040
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.040
negative regulation of cellular protein metabolic processGO:00322693530.040
cell morphogenesis involved in differentiationGO:00009041440.040
hematopoietic or lymphoid organ developmentGO:00485341860.039
hemopoiesisGO:00300971800.039
vasculature developmentGO:00019441810.039
negative regulation of cell cycleGO:00457861930.039
cation transportGO:00068123310.039
regulation of purine nucleotide metabolic processGO:19005422640.038
covalent chromatin modificationGO:00165692540.038
protein ubiquitinationGO:00165673140.038
regenerationGO:003109940.038
negative regulation of programmed cell deathGO:00430693210.038
immune responseGO:00069553070.038
cytoplasmic transportGO:00164823790.038
epithelial cell proliferationGO:00506731280.038
blood vessel developmentGO:00015681720.038
epithelium migrationGO:00901321190.038
intracellular protein transportGO:00068862700.037
positive regulation of nucleoside metabolic processGO:00459791860.037
epithelial cell migrationGO:00106311190.037
positive regulation of cell deathGO:00109422630.037
regulation of ras gtpase activityGO:00323181280.037
motor neuron axon guidanceGO:000804520.037
secretion by cellGO:00329402260.036
positive regulation of cell proliferationGO:00082843010.036
cellular macromolecule catabolic processGO:00442653800.036
cell substrate adhesionGO:00315891320.036
tissue migrationGO:00901301190.036
regulation of nucleotide metabolic processGO:00061402690.036
cell growthGO:00160491600.035
dephosphorylationGO:00163112090.035
ameboidal type cell migrationGO:00016671350.035
protein maturationGO:00516042330.035
chromatin organizationGO:00063253510.034
protein modification by small protein conjugationGO:00324463420.034
positive regulation of nucleotide metabolic processGO:00459812300.034
regulation of small gtpase mediated signal transductionGO:00510561560.034
organ formationGO:004864530.033
neuron differentiationGO:00301821380.033
negative regulation of phosphorus metabolic processGO:00105632670.033
cellular response to oxygen containing compoundGO:19017012760.033
blood vessel morphogenesisGO:00485141620.033
protein processingGO:00164852260.033
cellular response to transforming growth factor beta stimulusGO:0071560940.033
positive regulation of cellular catabolic processGO:00313312840.033
regulation of cell growthGO:00015581350.033
positive regulation of purine nucleotide metabolic processGO:19005442270.033
cellular response to cytokine stimulusGO:00713451810.032
response to cytokineGO:00340972320.032
cytokine mediated signaling pathwayGO:00192211090.032
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.032
apoptotic signaling pathwayGO:00971902680.031
Human
positive regulation of cell developmentGO:0010720920.031
regulation of peptidase activityGO:00525471800.031
neuron projection developmentGO:00311751060.031
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.031
establishment of protein localization to membraneGO:00901501210.031
chromatin modificationGO:00165682980.031
neuron developmentGO:00486661130.031
mitotic cell cycleGO:00002783260.031
positive regulation of nucleotide catabolic processGO:00308131850.030
generation of neuronsGO:00486991520.030
regulation of ras protein signal transductionGO:00465781550.030
cellular protein catabolic processGO:00442572610.030
transforming growth factor beta receptor signaling pathwayGO:0007179760.030
anion transportGO:00068201610.029
positive regulation of cell migrationGO:00303351720.029
cell fate determinationGO:000170930.029
defense responseGO:00069523150.029
response to woundingGO:00096111680.029
negative regulation of cellular component organizationGO:00511292350.029
negative regulation of intracellular signal transductionGO:19025321830.028
regulation of establishment of protein localizationGO:00702012420.028
positive regulation of transportGO:00510503360.028
positive regulation of programmed cell deathGO:00430682490.028
cellular homeostasisGO:00197251960.028
negative regulation of phosphate metabolic processGO:00459362670.028
multicellular organismal agingGO:001025930.027
cell junction organizationGO:0034330790.027
regulation of cellular response to growth factor stimulusGO:0090287760.027
positive regulation of ras gtpase activityGO:00323201170.027
negative regulation of cellular amino acid metabolic processGO:004576320.026
response to oxygen containing compoundGO:19017003690.026
positive regulation of cell motilityGO:20001471770.026
memoryGO:000761330.025
positive regulation of apoptotic processGO:00430652460.025
single organismal cell cell adhesionGO:00163371480.025
signal transduction by phosphorylationGO:00230142970.025
negative regulation of cellular amine metabolic processGO:003323930.025
innate immune responseGO:00450871780.025
maintenance of locationGO:00512351120.025
protein localization to organelleGO:00333652800.025
regulation of protein localizationGO:00328802960.025
cell cell junction organizationGO:0045216690.025
oocyte differentiationGO:000999420.025
positive regulation of intracellular transportGO:00323881040.025
small molecule biosynthetic processGO:00442831570.025
actin cytoskeleton organizationGO:00300362070.025
carbohydrate metabolic processGO:00059752070.025
ion transmembrane transportGO:00342203380.024
endocytosisGO:00068971590.024
oocyte developmentGO:004859910.024
regulation of intracellular transportGO:00323861950.024
secretionGO:00469032540.024
sensory perception of smellGO:000760820.024
positive regulation of gtpase activityGO:00435471660.024
mapk cascadeGO:00001652880.024
epithelial cell differentiationGO:00308551410.024
regulation of growthGO:00400081650.024
peptidyl tyrosine phosphorylationGO:00181081700.024
immune system developmentGO:00025201950.024
blastoderm segmentationGO:000735020.024
protein acylationGO:00435431380.024
muscle contractionGO:0006936730.024
Mouse
cytokine productionGO:00018162470.024
positive regulation of transferase activityGO:00513472270.023
protein targetingGO:00066051870.023
negative regulation of cell differentiationGO:00455961710.023
regulation of cell morphogenesisGO:00226041530.023
regulation of protein transportGO:00512232130.023
regulation of cysteine type endopeptidase activityGO:20001161270.023
negative regulation of proteolysisGO:00458611320.023
protein localization to membraneGO:00726571600.023
protein localization to nucleusGO:00345041360.023
glycoprotein metabolic processGO:00091001100.023
neurogenesisGO:00220081690.023
regulation of response to external stimulusGO:00321012220.023
regulation of cytokine productionGO:00018172320.023
response to transforming growth factor betaGO:0071559940.022
positive regulation of gtp catabolic processGO:00331261660.022
organic hydroxy compound metabolic processGO:19016151470.022
positive regulation of protein kinase activityGO:00458601900.022
i kappab kinase nf kappab signalingGO:00072491660.022
dna repairGO:00062811980.022
inorganic ion transmembrane transportGO:00986602310.022
regulation of cell projection organizationGO:00313441070.022
negative regulation of hydrolase activityGO:00513461820.022
regulation of epithelial cell migrationGO:0010632930.022
cell divisionGO:00513011680.022
negative regulation of protein modification processGO:00314002000.022
stem cell developmentGO:0048864690.022
specification of organ identityGO:001009230.022
metal ion transportGO:00300012720.022
endothelial cell migrationGO:0043542860.022
positive regulation of mapk cascadeGO:00434101900.022
lipid biosynthetic processGO:00086101770.022
tube morphogenesisGO:0035239950.022
locomotory behaviorGO:000762610.022
regulation of protein processingGO:00706131500.022
anterior posterior axis specificationGO:000994820.022
proteolysis involved in cellular protein catabolic processGO:00516032440.022
cell part morphogenesisGO:00329901370.022
regulation of protein maturationGO:19033171500.022
protein autophosphorylationGO:00467771230.021
posttranscriptional regulation of gene expressionGO:00106082130.021
negative regulation of locomotionGO:00400131180.021
regulation of wnt signaling pathwayGO:00301111230.021
regulation of mitotic cell cycleGO:00073461890.021
regulation of mapk cascadeGO:00434082620.021
ion homeostasisGO:00508012300.021
positive regulation of kinase activityGO:00336742040.021
regulation of actin filament based processGO:00329701410.021
positive regulation of cell projection organizationGO:0031346640.021
positive regulation of cellular component biogenesisGO:00440891580.021
spermatid differentiationGO:004851540.021
regulation of kinase activityGO:00435493140.021
positive regulation of organelle organizationGO:00106381950.021
cell junction assemblyGO:0034329670.021
positive regulation of cellular component movementGO:00512721810.021
peptidyl serine phosphorylationGO:00181051010.020
response to other organismGO:00517072610.020
interspecies interaction between organismsGO:00444191560.020
osteoblast differentiationGO:0001649920.020
tube developmentGO:00352951250.020
ossificationGO:00015031210.020
regulation of secretionGO:00510461940.020
reproductive processGO:00224141060.020
positive regulation of proteolysisGO:00458621420.020
negative regulation of growthGO:0045926970.020
embryonic morphogenesisGO:0048598850.020
salivary gland morphogenesisGO:000743540.020
compound eye developmentGO:004874910.020
peptidyl lysine modificationGO:00182051440.020
microtubule based processGO:00070172100.020
photoreceptor cell differentiationGO:004653020.020
cell matrix adhesionGO:0007160850.020
regulation of endopeptidase activityGO:00525481700.020
regulation of axon guidanceGO:190266730.020
lipid metabolic processGO:00066293810.020
regulation of protein kinase activityGO:00458592890.020
regulation of actin cytoskeleton organizationGO:00329561160.020
cell projection morphogenesisGO:00488581290.019
response to external biotic stimulusGO:00432072610.019
peptidyl tyrosine modificationGO:00182121700.019
cellular macromolecular complex assemblyGO:00346223240.019
symbiosis encompassing mutualism through parasitismGO:00444031560.019
response to oxidative stressGO:00069791210.019
intrinsic apoptotic signaling pathwayGO:00971931270.019
Human
cell projection assemblyGO:00300311260.019
hair follicle morphogenesisGO:003106920.019
response to organic cyclic compoundGO:00140702040.019
response to biotic stimulusGO:00096072760.019
organonitrogen compound biosynthetic processGO:19015662000.019
cell chemotaxisGO:00603261120.019
meiotic chromosome segregationGO:004513240.019
morphogenesis of an epitheliumGO:0002009600.019
cell cycle phase transitionGO:00447701730.019
regulation of multi organism processGO:00439001570.019
regulation of cytoplasmic transportGO:19036491490.019
peripheral nervous system developmentGO:000742220.019
cellular chemical homeostasisGO:00550821800.019
regulation of peptidyl tyrosine phosphorylationGO:00507301080.019
response to lipidGO:00339932060.019
regulation of vasculature developmentGO:1901342970.019
actin filament organizationGO:00070151280.018
cellular response to organic cyclic compoundGO:00714071270.018
nucleocytoplasmic transportGO:00069131760.018
neurological system processGO:00508771630.018
mitotic cell cycle processGO:19030472860.018
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.018
regulation of cell cycle processGO:00105642660.018
positive regulation of immune system processGO:00026842830.018
cellular lipid metabolic processGO:00442553030.018
viral life cycleGO:00190581320.018
embryonic epithelial tube formationGO:000183840.018
modification dependent protein catabolic processGO:00199412090.018
response to radiationGO:00093141510.018
carbohydrate derivative biosynthetic processGO:19011372070.018
regulation of i kappab kinase nf kappab signalingGO:00431221620.017
plasma membrane organizationGO:00070091150.017
cell activationGO:00017752130.017
neural tube patterningGO:002153220.017
positive regulation of cell adhesionGO:0045785840.017
glycoprotein biosynthetic processGO:0009101910.017
regulation of cellular component sizeGO:0032535820.017
response to organonitrogen compoundGO:00102431560.017
cellular protein complex assemblyGO:00436231880.017
regulation of synaptic plasticityGO:004816730.017
positive regulation of purine nucleotide catabolic processGO:00331231850.017
negative regulation of transportGO:00510511760.017
wound healingGO:00420601150.017
mesenchymal cell differentiationGO:0048762520.017
microtubule cytoskeleton organizationGO:00002261760.017
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.017
actin filament based movementGO:0030048170.017
neural tube formationGO:000184130.017
regulation of rho protein signal transductionGO:0035023790.017
cardiac muscle cell contractionGO:008600340.017
central nervous system developmentGO:00074171230.017
endothelial cell proliferationGO:0001935650.017
positive regulation of transcription during mitosisGO:004589720.017
cation transmembrane transportGO:00986552380.017
circadian behaviorGO:004851220.017
negative regulation of protein maturationGO:19033181420.017
atp metabolic processGO:00460341760.016
nuclear transportGO:00511691790.016
regulation of protein catabolic processGO:00421761550.016
organelle assemblyGO:00709251760.016
positive regulation of peptidase activityGO:0010952880.016
regulation of nervous system developmentGO:0051960880.016
endodermal cell fate specificationGO:000171440.016
positive regulation of protein transportGO:00512221350.016
proteasomal protein catabolic processGO:00104981760.016
spermatid developmentGO:000728640.016
regulation of bindingGO:00510981110.016
axis elongationGO:000340140.016
striated muscle contractionGO:0006941520.016
Mouse
negative regulation of cell proliferationGO:00082852280.016
negative regulation of cellular component movementGO:00512711060.016
behaviorGO:00076101120.016
regulation of transcription during mitosisGO:004589620.016
negative regulation of protein processingGO:00109551420.016
modification dependent macromolecule catabolic processGO:00436322120.016
stem cell differentiationGO:0048863930.016
regulation of rho gtpase activityGO:0032319660.016
keratinizationGO:003142420.016
brain developmentGO:0007420970.016
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015480.016
embryonic eye morphogenesisGO:004804820.015
multi organism cellular processGO:00447641560.015
response to virusGO:00096151260.015
digestive tract developmentGO:0048565750.015
post embryonic organ developmentGO:004856910.015
regulation of angiogenesisGO:0045765920.015
protein acetylationGO:00064731160.015
establishment of protein localization to organelleGO:00725941720.015
sensory perceptionGO:00076001030.015
lens development in camera type eyeGO:000208820.015
organelle fissionGO:00482851490.015
cellular response to abiotic stimulusGO:00712141170.015
reactive oxygen species biosynthetic processGO:190340940.015
embryonic forelimb morphogenesisGO:003511540.015
cellular response to nitrogen compoundGO:19016991440.015
regulation of intracellular protein transportGO:00331571230.015
response to axon injuryGO:004867810.015
nuclear divisionGO:00002801280.015
response to fungusGO:000962040.015
tripartite regional subdivisionGO:000735120.015
rab protein signal transductionGO:003248240.015
cellular cation homeostasisGO:00300031630.015
inorganic cation transmembrane transportGO:00986621940.015
ribonucleoside monophosphate metabolic processGO:00091611870.015
startle responseGO:000196430.015
regulation of vesicle mediated transportGO:00606271300.015
ubiquitin dependent protein catabolic processGO:00065112060.015
neuron projection regenerationGO:003110210.014
melanin metabolic processGO:000658210.014
neurotransmitter secretionGO:000726940.014
anterior posterior axis specification embryoGO:000859520.014
defense response to fungusGO:005083240.014
limbic system developmentGO:002176130.014
regulation of nucleocytoplasmic transportGO:0046822980.014
regulation of apoptotic signaling pathwayGO:20012331750.014
nucleoside monophosphate metabolic processGO:00091231910.014
regulation of protein targetingGO:1903533910.014
mammary gland morphogenesisGO:006044320.014
negative regulation of cell motilityGO:20001461040.014
negative regulation of organelle organizationGO:00106391260.014
cellular metal ion homeostasisGO:00068751460.014
regulation of response to dna damage stimulusGO:2001020940.014
mitochondrion organizationGO:00070051560.014
regulation of cell substrate adhesionGO:0010810680.014
embryo developmentGO:00097901230.014
Mouse
positive regulation of endopeptidase activityGO:0010950840.014
cellular component disassemblyGO:0022411920.014
neural crest cell developmentGO:001403230.014
morphogenesis of a polarized epitheliumGO:000173830.014
regulation of transmembrane transportGO:00347621390.014
chromosome segregationGO:00070591140.014
tissue regenerationGO:004224630.014
negative regulation of cell migrationGO:00303361020.014
response to hypoxiaGO:0001666960.014
viral processGO:00160321460.014
ribonucleoside monophosphate catabolic processGO:00091581580.014
negative regulation of cell growthGO:0030308830.014
regulation of chromosome organizationGO:00330441030.014
regulation of meiotic cell cycleGO:005144540.014
formation of primary germ layerGO:0001704420.014
heart developmentGO:0007507950.014
Mouse
cell aggregationGO:009874310.014
regulation of endothelial cell migrationGO:0010594670.014
negative regulation of wnt signaling pathwayGO:0030178690.014
developmental programmed cell deathGO:001062330.014
regulation of immune responseGO:00507762010.013
head developmentGO:00603221080.013
regulation of protein serine threonine kinase activityGO:00719001790.013
purine nucleoside monophosphate catabolic processGO:00091281580.013
peptidyl lysine acetylationGO:00183941010.013
immune effector processGO:00022521590.013
lipid localizationGO:00108761060.013
peptidyl serine modificationGO:00182091060.013
single organism reproductive processGO:0044702980.013
regulation of behaviorGO:0050795820.013
canonical wnt signaling pathwayGO:00600701160.013
calcium ion transportGO:00068161470.013
myeloid cell differentiationGO:00300991170.013
actin mediated cell contractionGO:0070252120.013
glycosylationGO:0070085710.013
lipid transportGO:0006869900.013
establishment of nucleus localizationGO:004002310.013

PPP1R13L disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.045
sensory system diseaseDOID:00501552030.045
musculoskeletal system diseaseDOID:172230.028
eye and adnexa diseaseDOID:14921500.018
eye diseaseDOID:56141490.018
bone diseaseDOID:0080001880.017
connective tissue diseaseDOID:651090.017
cancerDOID:1621670.015
disease of cellular proliferationDOID:145661740.015
disease of metabolismDOID:00146672950.015
organ system cancerDOID:00506861640.015
cardiovascular system diseaseDOID:12871060.014