Homo sapiens

79 known processes

PYCR1

pyrroline-5-carboxylate reductase 1

(Aliases: PIG45,PRO3,P5C,P5CR,ARCL2B,PP222,PYCR)

PYCR1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.176
cellular amino acid metabolic processGO:00065201160.171
organonitrogen compound biosynthetic processGO:19015662000.098
anion transportGO:00068201610.076
inorganic anion transmembrane transportGO:0098661470.074
transmembrane transportGO:00550853990.068
alpha amino acid metabolic processGO:1901605720.067
cellular amine metabolic processGO:0044106410.065
cellular ketone metabolic processGO:0042180800.065
regulation of cellular amine metabolic processGO:0033238110.063
regulation of cellular amino acid metabolic processGO:000652160.060
regulation of cellular ketone metabolic processGO:0010565500.058
negative regulation of apoptotic processGO:00430663160.058
amine metabolic processGO:0009308440.058
regulation of cell cycleGO:00517263930.055
organic anion transportGO:00157111030.055
negative regulation of catalytic activityGO:00430863350.054
carbohydrate metabolic processGO:00059752070.051
dicarboxylic acid metabolic processGO:0043648290.048
carboxylic acid transportGO:0046942630.047
ion transmembrane transportGO:00342203380.045
single organism carbohydrate metabolic processGO:00447231930.044
positive regulation of cellular amine metabolic processGO:003324070.041
negative regulation of protein metabolic processGO:00512483910.041
nitrogen compound transportGO:00717051910.041
negative regulation of programmed cell deathGO:00430693210.040
oogenesisGO:004847720.038
glutamine family amino acid metabolic processGO:0009064170.038
negative regulation of cell deathGO:00605483450.038
organic acid transportGO:0015849650.036
anion transmembrane transportGO:0098656760.036
response to abiotic stimulusGO:00096283360.036
female gamete generationGO:000729220.035
amino acid transportGO:0006865280.035
inorganic anion transportGO:0015698600.034
positive regulation of cellular amino acid metabolic processGO:004576430.034
monocarboxylic acid metabolic processGO:00327871850.034
positive regulation of phosphorylationGO:00423273940.034
negative regulation of phosphate metabolic processGO:00459362670.034
organophosphate catabolic processGO:00464344300.033
small gtpase mediated signal transductionGO:0007264780.032
chloride transmembrane transportGO:1902476380.032
secretionGO:00469032540.032
positive regulation of catabolic processGO:00098963100.032
negative regulation of cell proliferationGO:00082852280.031
apoptotic signaling pathwayGO:00971902680.031
negative regulation of phosphorus metabolic processGO:00105632670.031
positive regulation of protein phosphorylationGO:00019343130.031
cation transportGO:00068123310.030
positive regulation of immune system processGO:00026842830.030
cytoplasmic transportGO:00164823790.029
signal transduction by phosphorylationGO:00230142970.029
positive regulation of cellular catabolic processGO:00313312840.028
purine nucleoside triphosphate metabolic processGO:00091444120.028
negative regulation of cellular component organizationGO:00511292350.027
nucleoside phosphate catabolic processGO:19012924120.027
carboxylic acid biosynthetic processGO:0046394970.027
posttranscriptional regulation of gene expressionGO:00106082130.027
purine ribonucleoside triphosphate metabolic processGO:00092054110.027
epithelium developmentGO:00604292270.027
inorganic ion transmembrane transportGO:00986602310.026
cellular modified amino acid metabolic processGO:0006575640.026
purine ribonucleoside triphosphate catabolic processGO:00092073910.026
positive regulation of cellular component organizationGO:00511303760.026
guanosine containing compound metabolic processGO:19010682440.026
ribonucleoside triphosphate catabolic processGO:00092033910.025
response to lipidGO:00339932060.025
negative regulation of multicellular organismal processGO:00512413170.025
response to oxidative stressGO:00069791210.025
regulation of cellular component movementGO:00512703340.025
regulation of protein localizationGO:00328802960.025
determination of adult lifespanGO:000834020.024
segmentationGO:003528240.024
ribonucleoside catabolic processGO:00424544060.024
regulation of transferase activityGO:00513383550.024
proline transportGO:001582440.024
chloride transportGO:0006821410.024
rna processingGO:00063962550.023
dephosphorylationGO:00163112090.023
regulation of cellular response to stressGO:00801352440.023
response to oxygen containing compoundGO:19017003690.023
regulation of cell differentiationGO:00455953930.023
regulation of response to external stimulusGO:00321012220.023
negative regulation of hydrolase activityGO:00513461820.023
negative regulation of cellular amine metabolic processGO:003323930.023
purine ribonucleoside metabolic processGO:00461284370.023
positive regulation of cell proliferationGO:00082843010.022
organophosphate biosynthetic processGO:00904071630.022
negative regulation of developmental processGO:00510932470.022
sulfur compound metabolic processGO:00067901010.022
actin filament based processGO:00300292240.022
regulation of apoptotic signaling pathwayGO:20012331750.022
regulation of cell cycle processGO:00105642660.022
carboxylic acid catabolic processGO:0046395710.022
system processGO:00030083490.022
cellular component morphogenesisGO:00329893140.022
dna repairGO:00062811980.022
neuromuscular junction developmentGO:000752830.021
negative regulation of cellular protein metabolic processGO:00322693530.021
glycoprotein metabolic processGO:00091001100.021
mapk cascadeGO:00001652880.021
regulation of mitotic cell cycleGO:00073461890.020
cell cycle phase transitionGO:00447701730.020
rho protein signal transductionGO:0007266260.020
regulation of anatomical structure morphogenesisGO:00226032860.020
organic acid catabolic processGO:0016054710.020
cellular response to endogenous stimulusGO:00714953360.020
negative regulation of protein modification processGO:00314002000.020
ribonucleoside triphosphate metabolic processGO:00091994120.020
cell developmentGO:00484683280.020
regenerationGO:003109940.020
regulation of kinase activityGO:00435493140.020
regulation of purine nucleotide catabolic processGO:00331212050.020
positive regulation of purine nucleotide metabolic processGO:19005442270.019
mitotic cell cycle phase transitionGO:00447721620.019
regulation of secretionGO:00510461940.019
locomotory behaviorGO:000762610.019
purine ribonucleoside catabolic processGO:00461303980.019
single organism cellular localizationGO:19025803320.019
organic acid biosynthetic processGO:0016053970.019
oxidation reduction processGO:00551143960.019
modified amino acid transportGO:0072337110.019
response to organic cyclic compoundGO:00140702040.019
cellular protein complex assemblyGO:00436231880.019
ras protein signal transductionGO:0007265730.019
purine nucleotide catabolic processGO:00061954050.019
positive regulation of cell differentiationGO:00455972110.019
positive regulation of developmental processGO:00510943140.018
cellular response to dna damage stimulusGO:00069743790.018
spinal cord developmentGO:002151040.018
cellular lipid metabolic processGO:00442553030.018
regulation of protein catabolic processGO:00421761550.018
purine containing compound catabolic processGO:00725234110.018
lipid metabolic processGO:00066293810.018
mitochondrion organizationGO:00070051560.018
cellular macromolecular complex assemblyGO:00346223240.018
cell morphogenesisGO:00009022960.018
small molecule catabolic processGO:0044282920.018
negative regulation of cellular amino acid metabolic processGO:004576320.018
nucleoside triphosphate metabolic processGO:00091414220.018
glycoprotein biosynthetic processGO:0009101910.018
intracellular protein transportGO:00068862700.017
cellular protein catabolic processGO:00442572610.017
nuclear transportGO:00511691790.017
regulation of cell migrationGO:00303342890.017
nervous system developmentGO:00073992930.017
cell adhesionGO:00071553250.017
negative regulation of cell cycleGO:00457861930.017
regulation of protein kinase activityGO:00458592890.017
ribonucleotide catabolic processGO:00092614050.017
cellular macromolecule catabolic processGO:00442653800.017
regulation of nucleotide metabolic processGO:00061402690.017
protein ubiquitinationGO:00165673140.017
chemical homeostasisGO:00488783060.017
membrane organizationGO:00610242920.017
cell projection organizationGO:00300302520.017
blastoderm segmentationGO:000735020.017
biological adhesionGO:00226103310.017
regulation of purine nucleotide metabolic processGO:19005422640.017
regulation of protein complex assemblyGO:00432541470.017
response to radiationGO:00093141510.017
hindbrain developmentGO:003090230.017
growthGO:00400072020.016
metencephalon developmentGO:002203720.016
positive regulation of transportGO:00510503360.016
mitotic cell cycleGO:00002783260.016
gtp catabolic processGO:00061842370.016
immune responseGO:00069553070.016
positive regulation of purine nucleotide catabolic processGO:00331231850.016
oocyte differentiationGO:000999420.016
positive regulation of cell cycleGO:00457871400.016
regulation of dna metabolic processGO:00510521530.016
nucleotide catabolic processGO:00091664080.016
cofactor metabolic processGO:0051186870.016
glycosyl compound catabolic processGO:19016584130.016
regulation of cell motilityGO:20001452990.016
small molecule biosynthetic processGO:00442831570.016
protein localization to organelleGO:00333652800.016
ubiquitin dependent protein catabolic processGO:00065112060.016
multicellular organismal agingGO:001025930.016
syncytium formation by plasma membrane fusionGO:000076820.015
cell divisionGO:00513011680.015
blood circulationGO:00080151130.015
cation transmembrane transportGO:00986552380.015
mitotic cell cycle processGO:19030472860.015
protein secretionGO:0009306980.015
negative regulation of transferase activityGO:00513481240.015
protein maturationGO:00516042330.015
regulation of actin filament based processGO:00329701410.015
response to external biotic stimulusGO:00432072610.015
sulfur compound biosynthetic processGO:0044272380.015
positive regulation of locomotionGO:00400171860.015
neurological system processGO:00508771630.015
cellular response to abiotic stimulusGO:00712141170.015
purine nucleoside triphosphate catabolic processGO:00091463920.015
protein catabolic processGO:00301633250.015
response to biotic stimulusGO:00096072760.015
cardiac muscle cell contractionGO:008600340.015
oocyte developmentGO:004859910.015
hemopoiesisGO:00300971800.014
organelle assemblyGO:00709251760.014
positive regulation of cellular component biogenesisGO:00440891580.014
regulation of gtpase activityGO:00430871800.014
regulation of establishment of protein localizationGO:00702012420.014
maintenance of locationGO:00512351120.014
protein targetingGO:00066051870.014
purine nucleoside monophosphate metabolic processGO:00091261860.014
establishment of protein localization to organelleGO:00725941720.014
positive regulation of nucleoside metabolic processGO:00459791860.014
regulation of protein serine threonine kinase activityGO:00719001790.014
vesicle mediated transportGO:00161923710.014
fatty acid metabolic processGO:00066311150.014
reactive oxygen species biosynthetic processGO:190340940.014
regulation of proteolysisGO:00301622930.014
protein processingGO:00164852260.014
regulation of protein transportGO:00512232130.014
purine nucleoside catabolic processGO:00061523980.014
purine ribonucleotide catabolic processGO:00091544040.014
cell growthGO:00160491600.014
negative regulation of cell differentiationGO:00455961710.014
regulation of sequence specific dna binding transcription factor activityGO:00510902110.014
negative regulation of cellular component movementGO:00512711060.014
negative regulation of phosphorylationGO:00423261740.014
secretion by cellGO:00329402260.014
memoryGO:000761330.014
nucleoside triphosphate catabolic processGO:00091433940.014
regulation of protein maturationGO:19033171500.013
single organism membrane organizationGO:00448022680.013
spermatid differentiationGO:004851540.013
lipid biosynthetic processGO:00086101770.013
response to uvGO:0009411730.013
morphogenesis of embryonic epitheliumGO:001633140.013
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.013
nucleotide biosynthetic processGO:00091651090.013
regulation of growthGO:00400081650.013
anterior posterior axis specificationGO:000994820.013
nucleoside catabolic processGO:00091644080.013
cellular response to cytokine stimulusGO:00713451810.013
regulation of ras gtpase activityGO:00323181280.013
guanosine containing compound catabolic processGO:19010692390.013
rna interferenceGO:001624640.013
immune system developmentGO:00025201950.013
chromatin organizationGO:00063253510.013
negative regulation of intracellular signal transductionGO:19025321830.013
t cell differentiation in thymusGO:003307740.013
regulation of intracellular transportGO:00323861950.013
negative regulation of apoptotic signaling pathwayGO:2001234970.013
negative regulation of protein kinase activityGO:0006469980.013
cellular response to oxygen containing compoundGO:19017012760.013
ncrna metabolic processGO:00346601080.013
regulation of protein processingGO:00706131500.013
one carbon metabolic processGO:000673010.013
wnt signaling pathwayGO:00160551560.013
enzyme linked receptor protein signaling pathwayGO:00071673030.012
regulation of cytokine productionGO:00018172320.012
cytokine productionGO:00018162470.012
defense responseGO:00069523150.012
spermatid developmentGO:000728640.012
regulation of locomotionGO:00400123290.012
aminoglycan metabolic processGO:0006022390.012
negative regulation of protein phosphorylationGO:00019331400.012
regulation of dephosphorylationGO:0035303960.012
adult locomotory behaviorGO:000834410.012
negative regulation of protein maturationGO:19033181420.012
cell activationGO:00017752130.012
hematopoietic or lymphoid organ developmentGO:00485341860.012
regulation of cell developmentGO:00602841610.012
intrinsic apoptotic signaling pathwayGO:00971931270.012
anatomical structure formation involved in morphogenesisGO:00486462840.012
embryo developmentGO:00097901230.012
actin mediated cell contractionGO:0070252120.012
positive regulation of gtpase activityGO:00435471660.012
l amino acid importGO:004309240.012
establishment of protein localization to membraneGO:00901501210.012
endochondral bone morphogenesisGO:006035030.012
embryonic epithelial tube formationGO:000183840.012
negative regulation of phosphatase activityGO:0010923610.012
translationGO:00064121320.012
positive regulation of nucleotide metabolic processGO:00459812300.012
proteolysis involved in cellular protein catabolic processGO:00516032440.012
positive regulation of mitotic cell cycleGO:0045931600.012
protein oligomerizationGO:00512591730.012
tissue migrationGO:00901301190.012
glycosylationGO:0070085710.012
nucleoside monophosphate metabolic processGO:00091231910.012
negative regulation of protein processingGO:00109551420.012
cell projection assemblyGO:00300311260.012
regulation of cytoskeleton organizationGO:00514931770.012
blastocyst developmentGO:000182430.012
cellular response to hormone stimulusGO:00328701250.011
response to hypoxiaGO:0001666960.011
gtp metabolic processGO:00460392390.011
epithelial cell differentiationGO:00308551410.011
regulation of defense responseGO:00313471540.011
negative regulation of kinase activityGO:00336731060.011
reactive nitrogen species metabolic processGO:200105730.011
positive regulation of cell migrationGO:00303351720.011
positive regulation of proteolysisGO:00458621420.011
neurogenesisGO:00220081690.011
regulation of nucleotide catabolic processGO:00308112050.011
regulation of mitosisGO:0007088630.011
blastocyst formationGO:000182530.011
response to hormoneGO:00097251750.011
d aspartate transportGO:007077730.011
positive regulation of nucleotide catabolic processGO:00308131850.011
canonical wnt signaling pathwayGO:00600701160.011
regulation of reactive oxygen species metabolic processGO:2000377410.011
actin cytoskeleton organizationGO:00300362070.011
regulation of cell growthGO:00015581350.011
positive regulation of hydrolase activityGO:00513453310.011
regulation of growth rateGO:004000910.011
response to axon injuryGO:004867810.011
ribonucleoside monophosphate metabolic processGO:00091611870.011
positive regulation of gtp catabolic processGO:00331261660.011
organ formationGO:004864530.011
circulatory system processGO:00030131130.011
regulation of cardioblast differentiationGO:005189040.011
compound eye developmentGO:004874910.011
positive regulation of dna metabolic processGO:0051054730.011
response to other organismGO:00517072610.011
regulation of nucleoside metabolic processGO:00091182090.011
regulation of gtp catabolic processGO:00331241800.011
regulation of secretion by cellGO:19035301770.011
cellular homeostasisGO:00197251960.011
positive regulation of ras gtpase activityGO:00323201170.011
symbiosis encompassing mutualism through parasitismGO:00444031560.011
cellular response to lipidGO:00713961270.011
negative regulation of organelle organizationGO:00106391260.011
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.011
response to light stimulusGO:0009416870.011
regulation of protein stabilityGO:0031647870.011
sulfate transmembrane transportGO:190235830.011
regulation of response to dna damage stimulusGO:2001020940.011
regulation of mapk cascadeGO:00434082620.011
coenzyme metabolic processGO:0006732650.011
single organism nuclear importGO:19025931040.011
glycine metabolic processGO:000654440.011
startle responseGO:000196430.011
multi organism cellular processGO:00447641560.011
positive regulation of transferase activityGO:00513472270.010
monocarboxylic acid biosynthetic processGO:0072330670.010
regulation of ras protein signal transductionGO:00465781550.010
protein targeting to nucleusGO:00447441040.010
ion homeostasisGO:00508012300.010
innate immune responseGO:00450871780.010
myoblast fusionGO:000752010.010
l alanine transportGO:001580830.010
amino acid importGO:004309040.010
neural tube formationGO:000184130.010
neurotransmitter secretionGO:000726940.010
organic hydroxy compound metabolic processGO:19016151470.010
regulation of translationGO:0006417890.010
tripartite regional subdivisionGO:000735120.010
actin filament based movementGO:0030048170.010
protein localization to nucleusGO:00345041360.010
atp metabolic processGO:00460341760.010
plasma membrane organizationGO:00070091150.010
blood vessel developmentGO:00015681720.010
protein acylationGO:00435431380.010
modification dependent protein catabolic processGO:00199412090.010
response to organonitrogen compoundGO:00102431560.010
cellular amino acid biosynthetic processGO:0008652300.010
regulation of synaptic plasticityGO:004816730.010
alpha amino acid catabolic processGO:1901606260.010
protein modification by small protein conjugationGO:00324463420.010

PYCR1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.106
inherited metabolic disorderDOID:6552420.106
musculoskeletal system diseaseDOID:172230.062
bone diseaseDOID:0080001880.036
connective tissue diseaseDOID:651090.036
amino acid metabolic disorderDOID:9252500.031
bone development diseaseDOID:0080006550.028
cancerDOID:1621670.022
disease of cellular proliferationDOID:145661740.022
central nervous system diseaseDOID:3311860.019
nervous system diseaseDOID:8634310.019
organ system cancerDOID:00506861640.018
carbohydrate metabolic disorderDOID:2978550.018
neurodegenerative diseaseDOID:12891020.014
osteochondrodysplasiaDOID:2256350.012
brain diseaseDOID:936730.011