Homo sapiens

78 known processes

DFFA

DNA fragmentation factor, 45kDa, alpha polypeptide

(Aliases: DFF-45,ICAD,DFF1)

DFFA biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna catabolic processGO:0006308490.725
cellular macromolecule catabolic processGO:00442653800.409
cellular component disassembly involved in execution phase of apoptosisGO:0006921130.324
execution phase of apoptosisGO:0097194320.230
cellular component disassemblyGO:0022411920.207
purine nucleoside triphosphate catabolic processGO:00091463920.124
dna conformation changeGO:00711031130.120
cellular macromolecular complex assemblyGO:00346223240.116
gtp metabolic processGO:00460392390.116
negative regulation of cellular component organizationGO:00511292350.109
lipid metabolic processGO:00066293810.100
regulation of cellular ketone metabolic processGO:0010565500.090
small gtpase mediated signal transductionGO:0007264780.085
regulation of nucleoside metabolic processGO:00091182090.083
regulation of gtp catabolic processGO:00331241800.074
positive regulation of cellular amino acid metabolic processGO:004576430.070
positive regulation of cellular catabolic processGO:00313312840.069
nucleoside triphosphate catabolic processGO:00091433940.069
response to cytokineGO:00340972320.069
response to oxygen containing compoundGO:19017003690.066
guanosine containing compound catabolic processGO:19010692390.066
protein maturationGO:00516042330.065
protein processingGO:00164852260.064
cellular amino acid metabolic processGO:00065201160.060
positive regulation of purine nucleotide metabolic processGO:19005442270.060
nucleotide catabolic processGO:00091664080.060
glycosyl compound catabolic processGO:19016584130.058
ras protein signal transductionGO:0007265730.056
organophosphate catabolic processGO:00464344300.056
gtp catabolic processGO:00061842370.056
nucleoside catabolic processGO:00091644080.055
cellular lipid metabolic processGO:00442553030.055
positive regulation of catabolic processGO:00098963100.055
protein localization to organelleGO:00333652800.054
purine ribonucleoside triphosphate metabolic processGO:00092054110.054
nucleoside triphosphate metabolic processGO:00091414220.053
dna packagingGO:0006323770.052
regulation of nucleotide catabolic processGO:00308112050.051
purine nucleoside catabolic processGO:00061523980.051
positive regulation of hydrolase activityGO:00513453310.051
purine containing compound catabolic processGO:00725234110.049
ribonucleoprotein complex biogenesisGO:00226131160.049
regulation of purine nucleotide metabolic processGO:19005422640.048
negative regulation of cell deathGO:00605483450.048
apoptotic signaling pathwayGO:00971902680.047
positive regulation of cellular component organizationGO:00511303760.046
negative regulation of cellular protein metabolic processGO:00322693530.045
purine ribonucleoside catabolic processGO:00461303980.044
guanosine containing compound metabolic processGO:19010682440.044
negative regulation of hydrolase activityGO:00513461820.044
regulation of proteolysisGO:00301622930.044
regulation of nucleotide metabolic processGO:00061402690.043
cellular response to dna damage stimulusGO:00069743790.042
regulation of cell growthGO:00015581350.042
negative regulation of intracellular signal transductionGO:19025321830.041
determination of adult lifespanGO:000834020.040
cytoplasmic transportGO:00164823790.040
positive regulation of gtp catabolic processGO:00331261660.040
negative regulation of cell proliferationGO:00082852280.040
regulation of transferase activityGO:00513383550.039
biological adhesionGO:00226103310.039
cell adhesionGO:00071553250.039
post embryonic developmentGO:000979120.038
regulation of cellular component biogenesisGO:00440872810.038
negative regulation of protein metabolic processGO:00512483910.038
purine ribonucleoside metabolic processGO:00461284370.038
regulation of purine nucleotide catabolic processGO:00331212050.038
regulation of gtpase activityGO:00430871800.037
ribonucleotide catabolic processGO:00092614050.037
nervous system developmentGO:00073992930.037
amine metabolic processGO:0009308440.036
positive regulation of nucleotide metabolic processGO:00459812300.036
purine ribonucleoside triphosphate catabolic processGO:00092073910.036
regulation of cellular amino acid metabolic processGO:000652160.036
single organism cellular localizationGO:19025803320.036
response to abiotic stimulusGO:00096283360.035
purine ribonucleotide catabolic processGO:00091544040.035
neuromuscular junction developmentGO:000752830.035
posttranscriptional regulation of gene expressionGO:00106082130.034
ribonucleoside triphosphate catabolic processGO:00092033910.034
cellular ketone metabolic processGO:0042180800.034
negative regulation of protein modification processGO:00314002000.034
protein modification by small protein conjugationGO:00324463420.034
cellular response to abiotic stimulusGO:00712141170.033
positive regulation of nucleotide catabolic processGO:00308131850.033
positive regulation of cellular amine metabolic processGO:003324070.033
negative regulation of programmed cell deathGO:00430693210.033
cellular protein complex assemblyGO:00436231880.033
negative regulation of apoptotic processGO:00430663160.032
regulation of cellular response to stressGO:00801352440.032
regulation of response to dna damage stimulusGO:2001020940.031
regulation of cellular amine metabolic processGO:0033238110.031
response to organonitrogen compoundGO:00102431560.031
single organism membrane organizationGO:00448022680.030
negative regulation of cell cycleGO:00457861930.030
regulation of establishment of protein localizationGO:00702012420.030
nucleoside phosphate catabolic processGO:19012924120.030
regulation of protein localizationGO:00328802960.029
protein catabolic processGO:00301633250.029
negative regulation of organelle organizationGO:00106391260.029
regulation of cell cycleGO:00517263930.029
mitotic cell cycle phase transitionGO:00447721620.028
limbic system developmentGO:002176130.028
regulation of apoptotic signaling pathwayGO:20012331750.028
regulation of anatomical structure morphogenesisGO:00226032860.028
negative regulation of multicellular organismal processGO:00512413170.028
photoreceptor cell differentiationGO:004653020.027
rna interferenceGO:001624640.027
multicellular organismal agingGO:001025930.027
cellular amine metabolic processGO:0044106410.027
protein localization to membraneGO:00726571600.027
mitochondrion organizationGO:00070051560.027
positive regulation of programmed cell deathGO:00430682490.027
Mouse
positive regulation of cell deathGO:00109422630.027
Mouse
regulation of protein transportGO:00512232130.027
negative regulation of protein maturationGO:19033181420.026
response to nitrogen compoundGO:19016981840.026
nucleic acid phosphodiester bond hydrolysisGO:00903051020.025
ribonucleoside triphosphate metabolic processGO:00091994120.025
regulation of wnt signaling pathwayGO:00301111230.025
ribonucleoside catabolic processGO:00424544060.025
cell divisionGO:00513011680.024
intracellular protein transportGO:00068862700.024
rho protein signal transductionGO:0007266260.024
regulation of ras protein signal transductionGO:00465781550.024
rna splicingGO:00083801310.024
negative regulation of catalytic activityGO:00430863350.023
cellular response to oxygen containing compoundGO:19017012760.023
regulation of cysteine type endopeptidase activityGO:20001161270.023
regulation of protein bindingGO:0043393660.023
cellular protein catabolic processGO:00442572610.023
membrane organizationGO:00610242920.023
regulation of protein processingGO:00706131500.022
protein homooligomerizationGO:00512601000.022
mitotic cell cycleGO:00002783260.022
purine nucleotide catabolic processGO:00061954050.022
negative regulation of protein processingGO:00109551420.022
purine nucleoside triphosphate metabolic processGO:00091444120.022
cell type specific apoptotic processGO:00972851250.022
Mouse
purine containing compound biosynthetic processGO:0072522880.022
ncrna metabolic processGO:00346601080.022
regulation of cell migrationGO:00303342890.022
regulation of bindingGO:00510981110.022
organophosphate biosynthetic processGO:00904071630.022
microtubule based processGO:00070172100.021
positive regulation of nucleoside metabolic processGO:00459791860.021
cell substrate adhesionGO:00315891320.021
nucleoside phosphate biosynthetic processGO:19012931090.021
cellular component morphogenesisGO:00329893140.021
cellular response to cytokine stimulusGO:00713451810.021
regulation of protein kinase activityGO:00458592890.021
nucleotide biosynthetic processGO:00091651090.020
response to drugGO:0042493810.020
transmembrane transportGO:00550853990.020
negative regulation of proteolysisGO:00458611320.020
growthGO:00400072020.020
negative regulation of phosphate metabolic processGO:00459362670.020
nuclear transportGO:00511691790.020
negative regulation of phosphorylationGO:00423261740.020
neurogenesisGO:00220081690.020
negative regulation of cell cycle processGO:00109481210.020
regulation of cellular component movementGO:00512703340.020
organonitrogen compound biosynthetic processGO:19015662000.019
cell growthGO:00160491600.019
secretionGO:00469032540.019
single organism nuclear importGO:19025931040.019
protein import into nucleusGO:00066061040.019
regulation of kinase activityGO:00435493140.019
regulation of ras gtpase activityGO:00323181280.019
regulation of cytoskeleton organizationGO:00514931770.019
single organism carbohydrate metabolic processGO:00447231930.019
locomotory behaviorGO:000762610.019
phospholipid metabolic processGO:0006644990.019
extrinsic apoptotic signaling pathwayGO:00971911190.019
positive regulation of proteolysisGO:00458621420.018
cell cycle phase transitionGO:00447701730.018
cell projection organizationGO:00300302520.018
vesicle mediated transportGO:00161923710.018
negative regulation of developmental processGO:00510932470.018
regulation of cell motilityGO:20001452990.018
negative regulation of growthGO:0045926970.018
positive regulation of purine nucleotide catabolic processGO:00331231850.018
negative regulation of apoptotic signaling pathwayGO:2001234970.018
negative regulation of locomotionGO:00400131180.018
intrinsic apoptotic signaling pathwayGO:00971931270.018
positive regulation of ras gtpase activityGO:00323201170.018
negative regulation of transferase activityGO:00513481240.017
regulation of protein complex assemblyGO:00432541470.017
regulation of cellular protein catabolic processGO:1903362960.017
regulation of protein maturationGO:19033171500.017
regulation of endopeptidase activityGO:00525481700.017
memoryGO:000761330.017
proteolysis involved in cellular protein catabolic processGO:00516032440.017
cell morphogenesisGO:00009022960.017
positive regulation of apoptotic processGO:00430652460.017
Mouse
regulation of protein catabolic processGO:00421761550.017
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.017
regulation of intracellular protein transportGO:00331571230.016
protein targetingGO:00066051870.016
organelle assemblyGO:00709251760.016
mrna splicing via spliceosomeGO:0000398890.016
regulation of dna metabolic processGO:00510521530.016
translationGO:00064121320.016
cellular response to endogenous stimulusGO:00714953360.016
protein targeting to nucleusGO:00447441040.016
lipid biosynthetic processGO:00086101770.016
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.016
mitotic cell cycle processGO:19030472860.016
response to acid chemicalGO:0001101660.016
protein localization to plasma membraneGO:0072659930.016
positive regulation of transportGO:00510503360.016
regulation of peptidase activityGO:00525471800.016
response to peptideGO:1901652650.016
regulation of locomotionGO:00400123290.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.015
regulation of growthGO:00400081650.015
secretion by cellGO:00329402260.015
actin filament based processGO:00300292240.015
purine nucleotide biosynthetic processGO:0006164840.015
regulation of cell cycle processGO:00105642660.015
response to light stimulusGO:0009416870.015
response to radiationGO:00093141510.015
wnt signaling pathwayGO:00160551560.015
regulation of microtubule based processGO:0032886740.015
nuclear importGO:00511701060.015
establishment of protein localization to membraneGO:00901501210.015
negative regulation of protein phosphorylationGO:00019331400.015
proteasomal protein catabolic processGO:00104981760.015
positive regulation of dna metabolic processGO:0051054730.014
positive regulation of phosphorylationGO:00423273940.014
positive regulation of gtpase activityGO:00435471660.014
astrocyte differentiationGO:004870840.014
negative regulation of cell migrationGO:00303361020.014
carbohydrate metabolic processGO:00059752070.014
neurological system processGO:00508771630.014
negative regulation of cell motilityGO:20001461040.014
establishment of protein localization to organelleGO:00725941720.014
negative regulation of cellular component movementGO:00512711060.014
regulation of intracellular transportGO:00323861950.014
enzyme linked receptor protein signaling pathwayGO:00071673030.014
embryo developmentGO:00097901230.013
canonical wnt signaling pathwayGO:00600701160.013
anterior posterior axis specification embryoGO:000859520.013
negative regulation of phosphorus metabolic processGO:00105632670.013
response to organic cyclic compoundGO:00140702040.013
nucleocytoplasmic transportGO:00069131760.013
positive regulation of immune system processGO:00026842830.013
cell projection assemblyGO:00300311260.013
positive regulation of protein transportGO:00512221350.013
negative regulation of protein kinase activityGO:0006469980.013
mrna metabolic processGO:00160711750.013
rna processingGO:00063962550.013
chromatin organizationGO:00063253510.013
compound eye developmentGO:004874910.013
response to uvGO:0009411730.013
anterior posterior axis specificationGO:000994820.013
carbohydrate derivative biosynthetic processGO:19011372070.013
regulation of cell morphogenesisGO:00226041530.013
negative regulation of kinase activityGO:00336731060.013
protein oligomerizationGO:00512591730.013
neuron projection developmentGO:00311751060.013
endocytosisGO:00068971590.013
activation of immune responseGO:00022531140.013
negative regulation of cell growthGO:0030308830.013
positive regulation of peptidase activityGO:0010952880.013
segmentationGO:003528240.013
metal ion transportGO:00300012720.012
leukocyte activationGO:00453211640.012
receptor metabolic processGO:0043112810.012
mitochondrial membrane organizationGO:0007006400.012
negative regulation of catabolic processGO:00098951040.012
female gamete generationGO:000729220.012
somatic muscle developmentGO:000752510.012
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
response to external biotic stimulusGO:00432072610.012
multi organism cellular processGO:00447641560.012
ribosome biogenesisGO:0042254480.012
regulation of small gtpase mediated signal transductionGO:00510561560.012
single organism cell adhesionGO:00986021790.012
positive regulation of intracellular transportGO:00323881040.012
positive regulation of cell proliferationGO:00082843010.012
protein localization to nucleusGO:00345041360.012
divalent inorganic cation transportGO:00725111580.012
regenerationGO:003109940.012
axon cargo transportGO:000808820.012
covalent chromatin modificationGO:00165692540.012
positive regulation of cellular component biogenesisGO:00440891580.012
monocarboxylic acid metabolic processGO:00327871850.012
regulation of lipid metabolic processGO:0019216960.012
regulation of cytoplasmic transportGO:19036491490.012
organelle fissionGO:00482851490.012
ion transmembrane transportGO:00342203380.012
defense responseGO:00069523150.012
positive regulation of organelle organizationGO:00106381950.012
oxidation reduction processGO:00551143960.012
cation transportGO:00068123310.011
hippocampus developmentGO:002176610.011
regulation of cell morphogenesis involved in differentiationGO:0010769830.011
histone modificationGO:00165702510.011
purine ribonucleoside monophosphate metabolic processGO:00091671860.011
microtubule cytoskeleton organizationGO:00002261760.011
response to growth factorGO:00708482050.011
regulation of cell adhesionGO:00301551660.011
endomembrane system organizationGO:00102561960.011
neuron differentiationGO:00301821380.011
system processGO:00030083490.011
cell projection morphogenesisGO:00488581290.011
regulation of cell differentiationGO:00455953930.011
cellular response to nitrogen compoundGO:19016991440.011
glycosylationGO:0070085710.011
blastoderm segmentationGO:000735020.011
ribonucleoside monophosphate catabolic processGO:00091581580.011
negative regulation of mitotic cell cycleGO:00459301020.011
ribonucleoprotein complex assemblyGO:0022618780.011
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.011
regulation of cytokine productionGO:00018172320.011
glycoprotein metabolic processGO:00091001100.011
cellular response to uvGO:0034644320.011
establishment of protein localization to plasma membraneGO:0090002680.011
protein importGO:00170381300.011
oocyte developmentGO:004859910.011
adult locomotory behaviorGO:000834410.011
immune responseGO:00069553070.011
chromosome condensationGO:0030261150.011
positive regulation of protein catabolic processGO:0045732750.011
vasculature developmentGO:00019441810.011
plasma membrane organizationGO:00070091150.011
ion homeostasisGO:00508012300.011
negative regulation of cytoskeleton organizationGO:0051494450.011
cellular response to external stimulusGO:00714961110.011
oogenesisGO:004847720.010
regulation of ion transportGO:00432691890.010
mitotic cell cycle checkpointGO:0007093680.010
central nervous system developmentGO:00074171230.010
regulation of mitochondrion organizationGO:0010821540.010
positive regulation of developmental processGO:00510943140.010
negative regulation of response to dna damage stimulusGO:2001021330.010
taxisGO:00423301570.010
regulation of canonical wnt signaling pathwayGO:0060828880.010
regulation of feeding behaviorGO:006025930.010
cellular response to organonitrogen compoundGO:00714171240.010
muscle structure developmentGO:0061061980.010
protein ubiquitinationGO:00165673140.010
cell part morphogenesisGO:00329901370.010
regulation of protein localization to nucleusGO:1900180850.010

DFFA disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.065
disease of cellular proliferationDOID:145661740.027
cancerDOID:1621670.027
organ system cancerDOID:00506861640.027
inherited metabolic disorderDOID:6552420.020
nervous system diseaseDOID:8634310.018
neuropathyDOID:870520.018
neuromuscular diseaseDOID:440380.018
central nervous system diseaseDOID:3311860.016
neurodegenerative diseaseDOID:12891020.016
eye and adnexa diseaseDOID:14921500.012
sensory system diseaseDOID:00501552030.012
carbohydrate metabolic disorderDOID:2978550.011