Homo sapiens

11 known processes

CFI

complement factor I

(Aliases: KAF,C3b-INA,FI,AHUS3,C3BINA,IF)

CFI biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of complement activation lectin pathwayGO:000186920.857
negative regulation of protein activation cascadeGO:200025870.807
regulation of complement activation lectin pathwayGO:000186820.730
regulation of complement activationGO:003044980.344
protein activation cascadeGO:0072376220.313
positive regulation of acute inflammatory responseGO:000267520.310
negative regulation of complement activationGO:004591670.238
regulation of macrophage chemotaxisGO:001075840.235
negative regulation of humoral immune responseGO:000292170.221
regulation of triglyceride metabolic processGO:0090207110.214
regulation of protein activation cascadeGO:200025780.197
acylglycerol metabolic processGO:0006639270.194
positive regulation of immune system processGO:00026842830.183
regulation of cellular amine metabolic processGO:0033238110.182
cellular amine metabolic processGO:0044106410.170
amine metabolic processGO:0009308440.153
activation of immune responseGO:00022531140.142
positive regulation of cytokine productionGO:00018191670.142
regulation of defense responseGO:00313471540.138
positive regulation of protein phosphorylationGO:00019343130.136
defense responseGO:00069523150.135
g protein coupled receptor signaling pathwayGO:00071862070.134
cellular lipid metabolic processGO:00442553030.131
complement activationGO:0006956190.125
positive regulation of secretionGO:00510471160.119
regulation of response to woundingGO:19030341010.118
Human
cytokine productionGO:00018162470.117
protein maturationGO:00516042330.115
regulation of acute inflammatory response to antigenic stimulusGO:000286410.115
regulation of cytokine productionGO:00018172320.115
circulatory system developmentGO:00723592620.114
positive regulation of cellular amino acid metabolic processGO:004576430.114
regulation of cell migrationGO:00303342890.110
lipid metabolic processGO:00066293810.110
regulation of cellular amino acid metabolic processGO:000652160.105
protein processingGO:00164852260.103
negative regulation of protein maturationGO:19033181420.102
regulation of cellular ketone metabolic processGO:0010565500.102
complement activation lectin pathwayGO:000186770.097
positive regulation of transportGO:00510503360.097
negative regulation of protein metabolic processGO:00512483910.095
regulation of myeloid leukocyte mediated immunityGO:000288640.095
regulation of cytokine secretionGO:0050707570.095
cellular ketone metabolic processGO:0042180800.094
positive regulation of protein transportGO:00512221350.089
response to cytokineGO:00340972320.089
innate immune responseGO:00450871780.088
response to oxygen containing compoundGO:19017003690.086
humoral immune responseGO:0006959490.086
regulation of protein maturationGO:19033171500.084
positive regulation of immunoglobulin mediated immune responseGO:000289140.084
regulation of protein secretionGO:0050708860.084
regulation of immune responseGO:00507762010.083
blood vessel developmentGO:00015681720.083
positive regulation of secretion by cellGO:19035321080.083
positive regulation of cellular amine metabolic processGO:003324070.082
immune responseGO:00069553070.080
angiogenesisGO:00015251470.079
regulation of secretionGO:00510461940.078
cellular amino acid metabolic processGO:00065201160.077
negative regulation of catalytic activityGO:00430863350.076
regulation of protein transportGO:00512232130.076
protein secretionGO:0009306980.076
positive regulation of phosphorylationGO:00423273940.074
cytokine secretionGO:0050663640.073
glycerolipid metabolic processGO:00464861070.073
positive regulation of lipid storageGO:0010884100.073
regulation of protein localizationGO:00328802960.071
negative regulation of hydrolase activityGO:00513461820.071
regulation of secretion by cellGO:19035301770.069
regulation of protein processingGO:00706131500.069
regulation of establishment of protein localizationGO:00702012420.068
vasculature developmentGO:00019441810.068
negative regulation of defense responseGO:0031348470.068
cardiovascular system developmentGO:00723582620.068
immune effector processGO:00022521590.068
secretion by cellGO:00329402260.067
positive regulation of cellular component organizationGO:00511303760.067
chemokine productionGO:0032602320.066
positive regulation of humoral immune responseGO:000292230.065
blood vessel morphogenesisGO:00485141620.065
negative regulation of peptidase activityGO:0010466910.062
negative regulation of protein processingGO:00109551420.062
positive regulation of developmental processGO:00510943140.062
regulation of vasculature developmentGO:1901342970.062
regulation of locomotionGO:00400123290.060
negative regulation of cellular protein metabolic processGO:00322693530.060
triglyceride metabolic processGO:0006641230.060
regulation of immune effector processGO:0002697910.059
secretionGO:00469032540.059
negative regulation of proteolysisGO:00458611320.059
lipid biosynthetic processGO:00086101770.059
neutral lipid metabolic processGO:0006638270.059
regulation of response to external stimulusGO:00321012220.058
Human
cellular response to endogenous stimulusGO:00714953360.057
chemical homeostasisGO:00488783060.057
Human
regulation of inflammatory responseGO:0050727460.056
regulation of cell motilityGO:20001452990.056
regulation of peptidase activityGO:00525471800.055
glycerolipid biosynthetic processGO:0045017510.054
inflammatory response to antigenic stimulusGO:000243740.053
response to external biotic stimulusGO:00432072610.053
positive regulation of defense responseGO:0031349870.053
inflammatory responseGO:0006954790.052
response to woundingGO:00096111680.052
Human
oxidation reduction processGO:00551143960.052
negative regulation of immune system processGO:00026831360.051
leukocyte migrationGO:00509001070.050
cellular response to oxygen containing compoundGO:19017012760.049
positive regulation of immune responseGO:00507781590.048
response to organic cyclic compoundGO:00140702040.047
negative regulation of cell motilityGO:20001461040.047
lipid localizationGO:00108761060.046
regulation of proteolysisGO:00301622930.046
cell chemotaxisGO:00603261120.045
positive regulation of cytokine secretionGO:0050715420.045
post embryonic developmentGO:000979120.045
regulation of acute inflammatory responseGO:0002673130.044
vesicle mediated transportGO:00161923710.043
positive regulation of cell proliferationGO:00082843010.043
response to other organismGO:00517072610.042
maintenance of locationGO:00512351120.042
regulation of endopeptidase activityGO:00525481700.042
negative regulation of locomotionGO:00400131180.041
positive regulation of protein secretionGO:0050714600.041
sulfur compound metabolic processGO:00067901010.040
negative regulation of cell migrationGO:00303361020.039
negative regulation of multicellular organismal processGO:00512413170.039
Human
regulation of innate immune responseGO:0045088970.039
negative regulation of immune responseGO:0050777400.039
negative regulation of endopeptidase activityGO:0010951840.039
regulation of chemokine productionGO:0032642310.039
positive regulation of myeloid leukocyte mediated immunityGO:000288810.038
organonitrogen compound biosynthetic processGO:19015662000.038
acute inflammatory responseGO:0002526210.038
cellular response to cytokine stimulusGO:00713451810.037
positive regulation of protein processingGO:001095460.037
female gamete generationGO:000729220.036
positive regulation of b cell mediated immunityGO:000271440.036
regulation of cellular component movementGO:00512703340.035
biological adhesionGO:00226103310.035
multicellular organismal agingGO:001025930.035
system processGO:00030083490.035
acute inflammatory response to antigenic stimulusGO:000243810.034
negative regulation of leukocyte migrationGO:0002686140.033
negative regulation of immune effector processGO:0002698380.032
organophosphate catabolic processGO:00464344300.032
regenerationGO:003109940.032
regulation of leukocyte chemotaxisGO:0002688460.032
negative regulation of cellular component movementGO:00512711060.032
regulation of chemotaxisGO:0050920740.032
leukocyte chemotaxisGO:0030595760.032
regulation of lipid biosynthetic processGO:0046890470.032
regulation of g protein coupled receptor protein signaling pathwayGO:0008277350.032
nucleoside triphosphate metabolic processGO:00091414220.032
ribonucleoside triphosphate metabolic processGO:00091994120.031
regulation of angiogenesisGO:0045765920.031
organic hydroxy compound metabolic processGO:19016151470.031
purine containing compound catabolic processGO:00725234110.030
triglyceride biosynthetic processGO:0019432100.030
positive regulation of catabolic processGO:00098963100.030
regulation of anatomical structure morphogenesisGO:00226032860.030
peptidyl tyrosine phosphorylationGO:00181081700.030
positive regulation of chemokine productionGO:0032722220.030
acylglycerol biosynthetic processGO:0046463110.029
response to abiotic stimulusGO:00096283360.029
purine nucleoside triphosphate catabolic processGO:00091463920.029
lymphocyte mediated immunityGO:0002449480.029
purine ribonucleoside metabolic processGO:00461284370.029
cyclic nucleotide metabolic processGO:0009187820.029
leukocyte activationGO:00453211640.029
ribonucleoside catabolic processGO:00424544060.029
positive regulation of protein kinase activityGO:00458601900.029
regulation of behaviorGO:0050795820.028
purine ribonucleoside catabolic processGO:00461303980.028
positive regulation of response to external stimulusGO:0032103880.028
regulation of lipid metabolic processGO:0019216960.027
determination of adult lifespanGO:000834020.027
nucleotide catabolic processGO:00091664080.027
purine nucleoside triphosphate metabolic processGO:00091444120.027
purine ribonucleoside triphosphate catabolic processGO:00092073910.027
nucleoside phosphate catabolic processGO:19012924120.027
transmembrane transportGO:00550853990.026
multi organism cellular processGO:00447641560.026
regulation of vascular endothelial growth factor productionGO:0010574130.026
monocarboxylic acid metabolic processGO:00327871850.026
positive regulation of cell deathGO:00109422630.026
neutral lipid biosynthetic processGO:0046460110.026
negative regulation of response to external stimulusGO:0032102830.025
Human
carbohydrate derivative biosynthetic processGO:19011372070.025
ribonucleoside triphosphate catabolic processGO:00092033910.025
positive regulation of protein maturationGO:190331960.025
nitrogen compound transportGO:00717051910.025
divalent inorganic cation homeostasisGO:00725071360.025
carbohydrate metabolic processGO:00059752070.025
myeloid leukocyte migrationGO:0097529620.025
purine nucleoside catabolic processGO:00061523980.025
purine ribonucleoside triphosphate metabolic processGO:00092054110.025
peptidyl tyrosine modificationGO:00182121700.025
purine nucleotide catabolic processGO:00061954050.024
cellular response to growth factor stimulusGO:00713631970.024
regulation of leukocyte migrationGO:0002685630.024
response to biotic stimulusGO:00096072760.024
oogenesisGO:004847720.024
positive regulation of kinase activityGO:00336742040.024
positive regulation of hydrolase activityGO:00513453310.023
positive regulation of mapk cascadeGO:00434101900.023
anatomical structure formation involved in morphogenesisGO:00486462840.023
regulation of nucleotide metabolic processGO:00061402690.023
membrane organizationGO:00610242920.023
nervous system developmentGO:00073992930.023
single organism cellular localizationGO:19025803320.023
regulation of cellular response to stressGO:00801352440.022
segmentationGO:003528240.022
single organismal cell cell adhesionGO:00163371480.022
positive regulation of cellular catabolic processGO:00313312840.022
hemostasisGO:0007599760.022
Human
positive regulation of purine nucleotide metabolic processGO:19005442270.022
regulation of leukocyte mediated immunityGO:0002703380.022
signal transduction by phosphorylationGO:00230142970.022
carboxylic acid biosynthetic processGO:0046394970.021
cellular metal ion homeostasisGO:00068751460.021
locomotory behaviorGO:000762610.021
memoryGO:000761330.021
neuromuscular junction developmentGO:000752830.021
positive regulation of locomotionGO:00400171860.021
small gtpase mediated signal transductionGO:0007264780.021
ras protein signal transductionGO:0007265730.021
regulation of protein kinase activityGO:00458592890.021
cellular macromolecule catabolic processGO:00442653800.021
glycosyl compound catabolic processGO:19016584130.020
positive regulation of g protein coupled receptor protein signaling pathwayGO:004574590.020
negative regulation of cell proliferationGO:00082852280.020
leukocyte mediated immunityGO:0002443590.020
nucleoside triphosphate catabolic processGO:00091433940.020
single organism membrane organizationGO:00448022680.020
response to molecule of bacterial originGO:0002237820.020
mapk cascadeGO:00001652880.020
ion homeostasisGO:00508012300.020
Human
response to nitrogen compoundGO:19016981840.020
fatty acid metabolic processGO:00066311150.020
monosaccharide transportGO:0015749320.020
steroid metabolic processGO:0008202940.020
ion transmembrane transportGO:00342203380.019
anion transportGO:00068201610.019
glycoprotein metabolic processGO:00091001100.019
positive regulation of lymphocyte activationGO:0051251730.019
protein catabolic processGO:00301633250.019
positive regulation of nucleotide metabolic processGO:00459812300.019
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.019
organophosphate biosynthetic processGO:00904071630.019
regulation of purine nucleotide metabolic processGO:19005422640.019
positive regulation of purine nucleotide catabolic processGO:00331231850.019
cellular response to dna damage stimulusGO:00069743790.019
endocytosisGO:00068971590.019
lymphocyte activationGO:00466491330.019
regulation of mapk cascadeGO:00434082620.019
coagulationGO:0050817780.019
Human
positive regulation of cell differentiationGO:00455972110.018
response to growth factorGO:00708482050.018
positive regulation of angiogenesisGO:0045766510.018
purine ribonucleotide catabolic processGO:00091544040.018
nuclear transportGO:00511691790.018
cellular divalent inorganic cation homeostasisGO:00725031280.018
cellular response to hormone stimulusGO:00328701250.018
cytoplasmic transportGO:00164823790.018
positive regulation of nucleoside metabolic processGO:00459791860.018
negative regulation of cellular amine metabolic processGO:003323930.018
taxisGO:00423301570.018
cell morphogenesisGO:00009022960.018
negative regulation of transportGO:00510511760.018
positive regulation of leukocyte activationGO:0002696800.018
negative regulation of phosphate metabolic processGO:00459362670.018
spermatid differentiationGO:004851540.018
regulation of triglyceride biosynthetic processGO:001086650.018
hindbrain developmentGO:003090230.018
cell projection organizationGO:00300302520.018
reactive oxygen species metabolic processGO:0072593750.018
regulation of b cell mediated immunityGO:000271270.018
negative regulation of cellular amino acid metabolic processGO:004576320.018
t cell activationGO:0042110990.018
regulation of cell activationGO:00508651250.018
regulation of cellular component biogenesisGO:00440872810.018
inorganic ion transmembrane transportGO:00986602310.018
regulation of transferase activityGO:00513383550.018
nucleoside catabolic processGO:00091644080.018
single organism carbohydrate metabolic processGO:00447231930.018
hexose transportGO:0008645300.018
regulation of peptidyl tyrosine phosphorylationGO:00507301080.017
inorganic cation transmembrane transportGO:00986621940.017
nadph oxidationGO:007099530.017
negative regulation of leukocyte chemotaxisGO:000268950.017
ribonucleotide catabolic processGO:00092614050.017
regulation of sequence specific dna binding transcription factor activityGO:00510902110.017
regulation of endocytosisGO:0030100720.017
regulation of intracellular transportGO:00323861950.017
chemotaxisGO:00069351570.017
regulation of lymphocyte activationGO:00512491030.017
endomembrane system organizationGO:00102561960.017
reactive oxygen species biosynthetic processGO:190340940.017
thyroid hormone transportGO:007032720.017
cofactor metabolic processGO:0051186870.017
behaviorGO:00076101120.017
regulation of cell adhesionGO:00301551660.017
gtp metabolic processGO:00460392390.017
positive regulation of response to woundingGO:1903036280.017
apoptotic signaling pathwayGO:00971902680.017
negative regulation of intracellular signal transductionGO:19025321830.016
positive regulation vascular endothelial growth factor productionGO:0010575120.016
purine ribonucleoside monophosphate metabolic processGO:00091671860.016
purine nucleoside monophosphate metabolic processGO:00091261860.016
cation homeostasisGO:00550801890.016
Human
intracellular protein transportGO:00068862700.016
cellular protein catabolic processGO:00442572610.016
protein oligomerizationGO:00512591730.016
regulation of purine nucleotide catabolic processGO:00331212050.016
calcium ion homeostasisGO:00550741220.016
cation transmembrane transportGO:00986552380.016
positive regulation of apoptotic processGO:00430652460.016
negative regulation of apoptotic processGO:00430663160.016
negative regulation of cellular component organizationGO:00511292350.016
interspecies interaction between organismsGO:00444191560.016
response to organophosphorusGO:0046683410.016
metal ion transportGO:00300012720.016
cellular component morphogenesisGO:00329893140.016
organic acid biosynthetic processGO:0016053970.016
cellular homeostasisGO:00197251960.016
nucleoside monophosphate catabolic processGO:00091251590.016
posttranscriptional regulation of gene expressionGO:00106082130.016
response to hormoneGO:00097251750.016
negative regulation of vasculature developmentGO:1901343430.016
negative regulation of phosphorus metabolic processGO:00105632670.016
epithelium developmentGO:00604292270.016
Human
response to oxidative stressGO:00069791210.016
rhythmic behaviorGO:000762220.016
response to lipopolysaccharideGO:0032496700.016
response to organonitrogen compoundGO:00102431560.016
regulation of neural precursor cell proliferationGO:200017740.016
reactive nitrogen species metabolic processGO:200105730.016
proteolysis involved in cellular protein catabolic processGO:00516032440.015
adaptive immune responseGO:0002250490.015
cellular macromolecular complex assemblyGO:00346223240.015
positive regulation of transferase activityGO:00513472270.015
cell developmentGO:00484683280.015
positive regulation of synaptic transmissionGO:005080640.015
response to lipidGO:00339932060.015
negative regulation of programmed cell deathGO:00430693210.015
regulation of cell developmentGO:00602841610.015
mitotic cell cycle processGO:19030472860.015
regulation of nucleotide catabolic processGO:00308112050.015
viral processGO:00160321460.015
cellular response to organic cyclic compoundGO:00714071270.015
mitotic cell cycleGO:00002783260.015
cellular response to hydrogen peroxideGO:0070301370.015
regulation of hormone levelsGO:00108171250.015
organic anion transportGO:00157111030.015
cdc42 protein signal transductionGO:003248840.015
ribonucleoside monophosphate metabolic processGO:00091611870.015
organ formationGO:004864530.015
negative regulation of cell deathGO:00605483450.015
cation transportGO:00068123310.014
tissue regenerationGO:004224630.014
negative regulation of developmental processGO:00510932470.014
spermatid developmentGO:000728640.014
neurogenesisGO:00220081690.014
prostate gland morphogenesisGO:006051210.014
blastoderm segmentationGO:000735020.014
negative regulation of catabolic processGO:00098951040.014
small molecule catabolic processGO:0044282920.014
cell activationGO:00017752130.014
dephosphorylationGO:00163112090.014
gtp catabolic processGO:00061842370.014
neurological system processGO:00508771630.014
regulation of cytoplasmic transportGO:19036491490.014
guanosine containing compound catabolic processGO:19010692390.014
nucleoside monophosphate metabolic processGO:00091231910.014
oocyte developmentGO:004859910.014
response to radiationGO:00093141510.014
cellular response to nitrogen compoundGO:19016991440.014
single organism cell adhesionGO:00986021790.014
positive regulation of reactive oxygen species biosynthetic processGO:190342820.014
regulation of nucleoside metabolic processGO:00091182090.014
cytosolic calcium ion homeostasisGO:0051480890.014
response to hypoxiaGO:0001666960.014
sequestering of metal ionGO:0051238240.014
cell type specific apoptotic processGO:00972851250.014
actin filament based movementGO:0030048170.013
leukocyte proliferationGO:0070661740.013
peripheral nervous system developmentGO:000742220.013
positive regulation of t cell activationGO:0050870540.013
guanosine containing compound metabolic processGO:19010682440.013
regulation of protein catabolic processGO:00421761550.013
negative regulation of behaviorGO:0048521150.013
cellular ion homeostasisGO:00068731680.013
positive regulation of cytosolic calcium ion concentrationGO:0007204820.013
prostate gland developmentGO:003085030.013
regulation of synaptic plasticityGO:004816730.013
cardiac muscle cell contractionGO:008600340.013
hemopoiesisGO:00300971800.013
cell adhesionGO:00071553250.013
purine nucleoside monophosphate catabolic processGO:00091281580.013
regulation of cellular response to growth factor stimulusGO:0090287760.013
oocyte differentiationGO:000999420.013
lipid modificationGO:0030258840.013
defense response to other organismGO:00985421290.013
rho protein signal transductionGO:0007266260.013
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.013
neurotransmitter secretionGO:000726940.013
ribose phosphate biosynthetic processGO:0046390820.013
protein targetingGO:00066051870.013
protein localization to organelleGO:00333652800.013
cellular response to reactive oxygen speciesGO:0034614500.013
phospholipid metabolic processGO:0006644990.013
protein localization to membraneGO:00726571600.013
response to virusGO:00096151260.013
anterior posterior axis specificationGO:000994820.013
cellular response to biotic stimulusGO:0071216710.013
regulation of epithelial cell proliferationGO:00506781130.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002460400.013
regulation of humoral immune responseGO:0002920110.013
mitochondrion organizationGO:00070051560.013
response to axon injuryGO:004867810.013
positive regulation of erk1 and erk2 cascadeGO:0070374750.013
receptor metabolic processGO:0043112810.013
positive regulation of phagocytosisGO:0050766150.013
cyclic purine nucleotide metabolic processGO:0052652600.013
cellular chemical homeostasisGO:00550821800.013
regulation of intracellular protein transportGO:00331571230.013
positive regulation of immune effector processGO:0002699400.013
regulation of i kappab kinase nf kappab signalingGO:00431221620.013
response to bacteriumGO:00096171440.013
lipid catabolic processGO:0016042840.013
modification dependent macromolecule catabolic processGO:00436322120.013
inner ear morphogenesisGO:004247240.013
immune system developmentGO:00025201950.013
positive regulation of cellular component movementGO:00512721810.013
rna interferenceGO:001624640.013
positive regulation of glucose transportGO:0010828170.012
circadian behaviorGO:004851220.012
wound healingGO:00420601150.012
Human
purine ribonucleotide biosynthetic processGO:0009152790.012
regulation of cell cycleGO:00517263930.012
regulation of reactive oxygen species biosynthetic processGO:190342630.012
purine ribonucleoside monophosphate catabolic processGO:00091691580.012
small molecule biosynthetic processGO:00442831570.012
atp catabolic processGO:00062001570.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.012
morphogenesis of a polarized epitheliumGO:000173830.012
cellular amide metabolic processGO:0043603690.012
compound eye developmentGO:004874910.012
morphogenesis of embryonic epitheliumGO:001633140.012
negative regulation of cell cycleGO:00457861930.012
erk1 and erk2 cascadeGO:00703711040.012
anterior posterior axis specification embryoGO:000859520.012
cell fate determinationGO:000170930.012
neuron projection regenerationGO:003110210.012
regulation of kinase activityGO:00435493140.012
developmental programmed cell deathGO:001062330.012
regulation of vesicle mediated transportGO:00606271300.012
negative regulation of protein modification processGO:00314002000.012
cellular lipid catabolic processGO:0044242650.012
viral life cycleGO:00190581320.012
glycoprotein biosynthetic processGO:0009101910.012
positive regulation of nucleotide catabolic processGO:00308131850.012
symbiosis encompassing mutualism through parasitismGO:00444031560.012
response to campGO:0051591250.012
positive regulation of cell migrationGO:00303351720.012
regulation of cell differentiationGO:00455953930.012
sequestering of calcium ionGO:0051208170.012

CFI disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
normocytic anemiaDOID:720200.784
hematopoietic system diseaseDOID:741000.784
hemolytic anemiaDOID:583200.784
immune system diseaseDOID:29141550.784
anemiaDOID:2355550.784
hemolytic uremic syndromeDOID:1255480.758
macular degenerationDOID:4448200.289
retinal diseaseDOID:56791180.289
retinal degenerationDOID:8466890.289
nervous system diseaseDOID:8634310.289
eye and adnexa diseaseDOID:14921500.289
eye diseaseDOID:56141490.289
degeneration of macula and posterior poleDOID:2007170.289
sensory system diseaseDOID:00501552030.289
age related macular degenerationDOID:10871170.074
disease of metabolismDOID:00146672950.037
inherited metabolic disorderDOID:6552420.026
central nervous system diseaseDOID:3311860.022
disease of cellular proliferationDOID:145661740.022
cancerDOID:1621670.022
organ system cancerDOID:00506861640.019
disease of mental healthDOID:150700.015
acquired metabolic diseaseDOID:0060158580.015
neurodegenerative diseaseDOID:12891020.014
musculoskeletal system diseaseDOID:172230.013