Homo sapiens

27 known processes

NEK4

NIMA (never in mitosis gene a)-related kinase 4

(Aliases: STK2,pp12301,MGC33171,NRK2)

NEK4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cell cycle processGO:00105642660.102
Human
cellular ketone metabolic processGO:0042180800.084
cellular amino acid metabolic processGO:00065201160.077
female gamete generationGO:000729220.076
purine nucleoside triphosphate catabolic processGO:00091463920.074
amine metabolic processGO:0009308440.066
regulation of cellular amine metabolic processGO:0033238110.066
mitotic cell cycleGO:00002783260.065
regulation of cellular amino acid metabolic processGO:000652160.063
protein ubiquitinationGO:00165673140.058
cellular amine metabolic processGO:0044106410.057
nucleoside phosphate catabolic processGO:19012924120.056
regulation of cell cycleGO:00517263930.054
Human
microtubule based processGO:00070172100.051
post embryonic developmentGO:000979120.047
nucleotide catabolic processGO:00091664080.047
regulation of cellular ketone metabolic processGO:0010565500.044
purine ribonucleoside metabolic processGO:00461284370.043
glycosyl compound catabolic processGO:19016584130.041
nucleoside catabolic processGO:00091644080.040
nucleoside triphosphate catabolic processGO:00091433940.038
purine nucleotide catabolic processGO:00061954050.038
cellular response to dna damage stimulusGO:00069743790.037
purine containing compound catabolic processGO:00725234110.035
positive regulation of cellular amine metabolic processGO:003324070.035
oogenesisGO:004847720.035
ribonucleoside catabolic processGO:00424544060.034
mitotic cell cycle processGO:19030472860.034
Human
purine nucleoside catabolic processGO:00061523980.034
negative regulation of cellular protein metabolic processGO:00322693530.033
cytoplasmic transportGO:00164823790.033
anatomical structure formation involved in morphogenesisGO:00486462840.032
maintenance of locationGO:00512351120.032
cellular macromolecular complex assemblyGO:00346223240.032
purine ribonucleotide catabolic processGO:00091544040.031
purine nucleoside triphosphate metabolic processGO:00091444120.031
organophosphate catabolic processGO:00464344300.031
ribonucleoside triphosphate metabolic processGO:00091994120.031
oocyte developmentGO:004859910.030
multicellular organismal agingGO:001025930.029
small molecule biosynthetic processGO:00442831570.028
nucleoside triphosphate metabolic processGO:00091414220.028
cell cell signalingGO:00072671550.028
lipid metabolic processGO:00066293810.028
cell projection organizationGO:00300302520.028
purine ribonucleoside monophosphate metabolic processGO:00091671860.027
cellular component morphogenesisGO:00329893140.027
purine ribonucleoside triphosphate catabolic processGO:00092073910.027
regulation of cytoskeleton organizationGO:00514931770.027
ribonucleoside triphosphate catabolic processGO:00092033910.027
negative regulation of protein metabolic processGO:00512483910.027
regulation of cellular component biogenesisGO:00440872810.027
regulation of protein localizationGO:00328802960.027
protein catabolic processGO:00301633250.026
protein oligomerizationGO:00512591730.026
cell morphogenesisGO:00009022960.026
negative regulation of programmed cell deathGO:00430693210.026
carbohydrate metabolic processGO:00059752070.025
regulation of dna metabolic processGO:00510521530.025
positive regulation of cellular amino acid metabolic processGO:004576430.025
mitotic cell cycle phase transitionGO:00447721620.025
Human
ribonucleotide catabolic processGO:00092614050.025
vesicle mediated transportGO:00161923710.025
determination of adult lifespanGO:000834020.024
regulation of kinase activityGO:00435493140.024
protein localization to organelleGO:00333652800.024
chemical homeostasisGO:00488783060.024
protein modification by small protein conjugationGO:00324463420.024
purine ribonucleoside triphosphate metabolic processGO:00092054110.024
regulation of cellular response to stressGO:00801352440.024
positive regulation of hydrolase activityGO:00513453310.023
mrna metabolic processGO:00160711750.023
nervous system developmentGO:00073992930.023
cell divisionGO:00513011680.023
organic acid biosynthetic processGO:0016053970.022
organelle assemblyGO:00709251760.022
rna processingGO:00063962550.022
organonitrogen compound biosynthetic processGO:19015662000.021
positive regulation of cellular component organizationGO:00511303760.021
purine ribonucleoside catabolic processGO:00461303980.021
oocyte differentiationGO:000999420.021
positive regulation of catabolic processGO:00098963100.021
single organism cellular localizationGO:19025803320.021
response to abiotic stimulusGO:00096283360.021
positive regulation of protein phosphorylationGO:00019343130.020
positive regulation of phosphorylationGO:00423273940.020
cell projection assemblyGO:00300311260.020
negative regulation of cellular amine metabolic processGO:003323930.020
dna repairGO:00062811980.020
response to oxygen containing compoundGO:19017003690.020
carboxylic acid biosynthetic processGO:0046394970.020
membrane organizationGO:00610242920.020
negative regulation of cellular amino acid metabolic processGO:004576320.019
cell projection morphogenesisGO:00488581290.019
regulation of response to dna damage stimulusGO:2001020940.019
dephosphorylationGO:00163112090.019
monocarboxylic acid metabolic processGO:00327871850.019
purine nucleoside monophosphate metabolic processGO:00091261860.019
organelle fissionGO:00482851490.019
actin filament based processGO:00300292240.019
protein maturationGO:00516042330.019
neurotransmitter secretionGO:000726940.019
secretionGO:00469032540.018
nuclear divisionGO:00002801280.018
embryonic epithelial tube formationGO:000183840.018
microtubule cytoskeleton organizationGO:00002261760.018
negative regulation of cell cycle processGO:00109481210.018
Human
negative regulation of phosphorus metabolic processGO:00105632670.018
regulation of establishment of protein localizationGO:00702012420.018
single organism carbohydrate metabolic processGO:00447231930.018
organic hydroxy compound metabolic processGO:19016151470.018
cellular homeostasisGO:00197251960.018
immune responseGO:00069553070.018
locomotory behaviorGO:000762610.018
regulation of transferase activityGO:00513383550.018
secretion by cellGO:00329402260.017
segmentationGO:003528240.017
negative regulation of catalytic activityGO:00430863350.017
nitrogen compound transportGO:00717051910.017
sister chromatid segregationGO:0000819540.017
neuromuscular junction developmentGO:000752830.017
cell part morphogenesisGO:00329901370.017
mitotic nuclear divisionGO:00070671190.017
microtubule organizing center organizationGO:0031023620.017
endomembrane system organizationGO:00102561960.017
regulation of intracellular transportGO:00323861950.017
spermatid differentiationGO:004851540.017
single organism membrane organizationGO:00448022680.017
positive regulation of transportGO:00510503360.017
negative regulation of transferase activityGO:00513481240.017
chromosome segregationGO:00070591140.016
regulation of protein kinase activityGO:00458592890.016
positive regulation of purine nucleotide metabolic processGO:19005442270.016
regulation of growthGO:00400081650.016
ras protein signal transductionGO:0007265730.016
wnt signaling pathwayGO:00160551560.016
ribonucleoside monophosphate catabolic processGO:00091581580.016
cellular response to oxygen containing compoundGO:19017012760.016
cellular lipid metabolic processGO:00442553030.016
regulation of mitotic cell cycleGO:00073461890.016
Human
purine nucleoside monophosphate catabolic processGO:00091281580.016
regulation of cell divisionGO:00513021160.016
regulation of anatomical structure morphogenesisGO:00226032860.016
positive regulation of organelle organizationGO:00106381950.016
regulation of cell motilityGO:20001452990.016
negative regulation of cell deathGO:00605483450.016
biological adhesionGO:00226103310.016
nucleoside monophosphate metabolic processGO:00091231910.015
regulation of proteolysisGO:00301622930.015
regulation of multi organism processGO:00439001570.015
meiosis iGO:000712740.015
protein targetingGO:00066051870.015
regulation of protein complex assemblyGO:00432541470.015
rna splicingGO:00083801310.015
regulation of wnt signaling pathwayGO:00301111230.015
innate immune responseGO:00450871780.015
positive regulation of cellular component biogenesisGO:00440891580.015
defense responseGO:00069523150.015
negative regulation of apoptotic processGO:00430663160.015
ribonucleoside monophosphate metabolic processGO:00091611870.015
negative regulation of phosphorylationGO:00423261740.015
cytokinesisGO:0000910960.015
positive regulation of cell deathGO:00109422630.015
regulation of cell differentiationGO:00455953930.015
mapk cascadeGO:00001652880.014
regulation of cytoplasmic transportGO:19036491490.014
sulfur compound metabolic processGO:00067901010.014
positive regulation of immune system processGO:00026842830.014
maintenance of protein locationGO:0045185570.014
cellular component disassemblyGO:0022411920.014
cilium assemblyGO:0042384630.014
negative regulation of organelle organizationGO:00106391260.014
regulation of nucleotide metabolic processGO:00061402690.014
positive regulation of cellular catabolic processGO:00313312840.014
positive regulation of apoptotic processGO:00430652460.014
spermatid developmentGO:000728640.014
fatty acid metabolic processGO:00066311150.014
regulation of microtubule based processGO:0032886740.014
regenerationGO:003109940.014
negative regulation of protein modification processGO:00314002000.014
compound eye developmentGO:004874910.014
canonical wnt signaling pathwayGO:00600701160.014
negative regulation of cellular component organizationGO:00511292350.014
regulation of mapk cascadeGO:00434082620.014
protein processingGO:00164852260.014
positive regulation of cell proliferationGO:00082843010.014
cellular protein catabolic processGO:00442572610.014
signal transduction by phosphorylationGO:00230142970.013
guanosine containing compound metabolic processGO:19010682440.013
negative regulation of phosphate metabolic processGO:00459362670.013
system processGO:00030083490.013
negative regulation of protein phosphorylationGO:00019331400.013
response to hormoneGO:00097251750.013
mrna processingGO:00063971330.013
cellular protein complex assemblyGO:00436231880.013
protein methylationGO:0006479740.013
cilium morphogenesisGO:0060271750.013
mitotic sister chromatid segregationGO:0000070530.013
regulation of purine nucleotide metabolic processGO:19005422640.013
atp catabolic processGO:00062001570.013
intracellular protein transportGO:00068862700.013
peripheral nervous system developmentGO:000742220.013
somitogenesisGO:000175620.013
cell adhesionGO:00071553250.013
organelle localizationGO:0051640840.013
purine ribonucleoside monophosphate catabolic processGO:00091691580.013
carbohydrate derivative biosynthetic processGO:19011372070.013
regulation of meiotic cell cycleGO:005144540.013
endocytosisGO:00068971590.013
tube developmentGO:00352951250.013
intracellular receptor signaling pathwayGO:00305221040.012
positive regulation of kinase activityGO:00336742040.012
regulation of purine nucleotide catabolic processGO:00331212050.012
negative regulation of cell cycleGO:00457861930.012
Human
chromatin organizationGO:00063253510.012
small gtpase mediated signal transductionGO:0007264780.012
chromatin modificationGO:00165682980.012
cellular component assembly involved in morphogenesisGO:0010927730.012
mrna splicing via spliceosomeGO:0000398890.012
positive regulation of gtp catabolic processGO:00331261660.012
centrosome organizationGO:0051297580.012
covalent chromatin modificationGO:00165692540.012
positive regulation of nucleotide catabolic processGO:00308131850.012
response to other organismGO:00517072610.012
positive regulation of programmed cell deathGO:00430682490.012
nucleocytoplasmic transportGO:00069131760.012
symbiosis encompassing mutualism through parasitismGO:00444031560.012
regulation of microtubule cytoskeleton organizationGO:0070507610.012
regulation of cell morphogenesisGO:00226041530.012
regulation of protein transportGO:00512232130.012
reproductive processGO:00224141060.012
lipid modificationGO:0030258840.012
organophosphate biosynthetic processGO:00904071630.012
maintenance of protein location in cellGO:0032507560.012
negative regulation of transportGO:00510511760.012
macromolecule methylationGO:0043414970.012
response to external biotic stimulusGO:00432072610.012
positive regulation of protein kinase activityGO:00458601900.011
cell morphogenesis involved in differentiationGO:00009041440.011
cilium organizationGO:0044782680.011
growthGO:00400072020.011
regulation of cell cycle phase transitionGO:19019871260.011
Human
rho protein signal transductionGO:0007266260.011
endosomal transportGO:00161971290.011
atp metabolic processGO:00460341760.011
regulation of cellular component movementGO:00512703340.011
positive regulation of transferase activityGO:00513472270.011
regulation of intracellular protein transportGO:00331571230.011
negative regulation of kinase activityGO:00336731060.011
regulation of protein ubiquitinationGO:0031396950.011
regulation of secretion by cellGO:19035301770.011
neuron projection developmentGO:00311751060.011
response to bacteriumGO:00096171440.011
receptor mediated endocytosisGO:0006898840.011
neurogenesisGO:00220081690.011
protein complex disassemblyGO:0043241520.011
response to cytokineGO:00340972320.011
regulation of mitotic cell cycle phase transitionGO:19019901180.011
Human
central nervous system developmentGO:00074171230.011
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.011
glycerophospholipid metabolic processGO:0006650840.011
chemotaxisGO:00069351570.011
rna interferenceGO:001624640.011
regulation of cell projection organizationGO:00313441070.011
regulation of cytokine productionGO:00018172320.011
negative regulation of multicellular organismal processGO:00512413170.011
interspecies interaction between organismsGO:00444191560.011
nucleoside monophosphate catabolic processGO:00091251590.011
cytokine productionGO:00018162470.011
regulation of response to external stimulusGO:00321012220.011
positive regulation of protein transportGO:00512221350.011
proteolysis involved in cellular protein catabolic processGO:00516032440.011
guanosine containing compound catabolic processGO:19010692390.011
cellular response to endogenous stimulusGO:00714953360.011
meiotic chromosome segregationGO:004513240.010
neural tube closureGO:000184330.010
cellular response to cytokine stimulusGO:00713451810.010
epithelium developmentGO:00604292270.010
response to radiationGO:00093141510.010
regulation of protein catabolic processGO:00421761550.010
nuclear transportGO:00511691790.010
regulation of cell migrationGO:00303342890.010
regulation of locomotionGO:00400123290.010
viral processGO:00160321460.010
regulation of protein depolymerizationGO:1901879220.010
positive regulation of proteolysisGO:00458621420.010
establishment of protein localization to organelleGO:00725941720.010
ubiquitin dependent protein catabolic processGO:00065112060.010
tissue morphogenesisGO:0048729960.010
matingGO:000761810.010
regulation of dna repairGO:0006282470.010

NEK4 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.035
inherited metabolic disorderDOID:6552420.024
nervous system diseaseDOID:8634310.021
central nervous system diseaseDOID:3311860.021
disease of cellular proliferationDOID:145661740.017
cancerDOID:1621670.016
organ system cancerDOID:00506861640.012
musculoskeletal system diseaseDOID:172230.011