Homo sapiens

42 known processes

NEK1

NIMA (never in mitosis gene a)-related kinase 1

(Aliases: DKFZp686D06121,NY-REN-55,DKFZp686K12169,MGC138800,SRPS2,KIAA1901)

NEK1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cilium assemblyGO:0042384630.485
cilium morphogenesisGO:0060271750.482
glial cell migrationGO:000834740.371
cardiovascular system developmentGO:00723582620.311
sensory perception of smellGO:000760820.299
neural tube patterningGO:002153220.280
purine ribonucleoside catabolic processGO:00461303980.215
cilium organizationGO:0044782680.203
purine nucleotide catabolic processGO:00061954050.200
cell projection organizationGO:00300302520.187
ribonucleotide catabolic processGO:00092614050.186
ribonucleoside monophosphate catabolic processGO:00091581580.180
purine containing compound catabolic processGO:00725234110.164
organophosphate catabolic processGO:00464344300.160
regulation of wnt signaling pathwayGO:00301111230.150
positive regulation of cellular component organizationGO:00511303760.144
replication fork processingGO:0031297130.141
purine nucleoside triphosphate metabolic processGO:00091444120.138
anterograde axon cargo transportGO:000808910.137
epithelium developmentGO:00604292270.137
determination of adult lifespanGO:000834020.136
cellular response to dna damage stimulusGO:00069743790.131
Mouse
dna conformation changeGO:00711031130.130
cell projection morphogenesisGO:00488581290.130
ribonucleoside triphosphate metabolic processGO:00091994120.125
purine ribonucleoside monophosphate catabolic processGO:00091691580.121
cell developmentGO:00484683280.116
wnt signaling pathwayGO:00160551560.116
organelle fissionGO:00482851490.112
nucleoside catabolic processGO:00091644080.109
organelle assemblyGO:00709251760.109
glycosyl compound catabolic processGO:19016584130.105
purine nucleoside monophosphate metabolic processGO:00091261860.102
purine nucleoside triphosphate catabolic processGO:00091463920.101
neuron differentiationGO:00301821380.100
neuron projection developmentGO:00311751060.100
purine nucleoside monophosphate catabolic processGO:00091281580.100
purine ribonucleoside triphosphate catabolic processGO:00092073910.099
purine ribonucleoside triphosphate metabolic processGO:00092054110.095
chemotaxisGO:00069351570.094
establishment or maintenance of microtubule cytoskeleton polarityGO:003095120.092
cellular component morphogenesisGO:00329893140.090
nervous system developmentGO:00073992930.083
mitotic cell cycleGO:00002783260.081
nucleoside phosphate catabolic processGO:19012924120.077
cellular component assembly involved in morphogenesisGO:0010927730.077
taxisGO:00423301570.077
generation of neuronsGO:00486991520.076
purine ribonucleoside monophosphate metabolic processGO:00091671860.076
negative regulation of protein metabolic processGO:00512483910.076
regulation of cell cycleGO:00517263930.075
anatomical structure formation involved in morphogenesisGO:00486462840.075
ribonucleoside monophosphate metabolic processGO:00091611870.074
regulation of cell differentiationGO:00455953930.074
tube developmentGO:00352951250.074
cell morphogenesisGO:00009022960.073
system processGO:00030083490.072
microtubule cytoskeleton organizationGO:00002261760.070
axon cargo transportGO:000808820.069
purine nucleoside catabolic processGO:00061523980.068
nucleoside triphosphate catabolic processGO:00091433940.068
microtubule based processGO:00070172100.067
neurogenesisGO:00220081690.067
nucleotide catabolic processGO:00091664080.065
female gamete generationGO:000729220.064
regulation of protein maturationGO:19033171500.064
mitotic nuclear divisionGO:00070671190.061
chromatin assemblyGO:0031497610.059
dna replicationGO:00062601160.057
establishment or maintenance of cytoskeleton polarityGO:003095230.055
ribonucleoside catabolic processGO:00424544060.055
regulation of cell cycle processGO:00105642660.054
dna dependent dna replicationGO:0006261440.054
cell projection assemblyGO:00300311260.053
neuron developmentGO:00486661130.052
cell part morphogenesisGO:00329901370.052
circulatory system developmentGO:00723592620.052
cellular macromolecule catabolic processGO:00442653800.051
inorganic cation transmembrane transportGO:00986621940.051
positive regulation of cell cycleGO:00457871400.050
regulation of meiotic cell cycleGO:005144540.050
microtubule based movementGO:0007018320.050
cell morphogenesis involved in differentiationGO:00009041440.049
nucleoside monophosphate metabolic processGO:00091231910.049
cranial nerve developmentGO:002154540.048
negative regulation of developmental processGO:00510932470.047
atp catabolic processGO:00062001570.047
regulation of transporter activityGO:0032409820.047
sodium ion transportGO:0006814610.046
purine ribonucleotide catabolic processGO:00091544040.046
ion homeostasisGO:00508012300.043
positive regulation of organelle organizationGO:00106381950.043
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.042
positive regulation of cell cycle processGO:00900681060.042
regulation of protein localizationGO:00328802960.042
anatomical structure homeostasisGO:00602491000.041
nucleoside triphosphate metabolic processGO:00091414220.041
chromatin modificationGO:00165682980.041
telomere maintenanceGO:0000723320.040
memoryGO:000761330.040
chemical homeostasisGO:00488783060.040
sodium ion transmembrane transportGO:0035725590.040
positive regulation of telomere maintenanceGO:003220640.040
regulation of ion transmembrane transportGO:00347651320.039
atp metabolic processGO:00460341760.038
regulation of epithelial cell proliferationGO:00506781130.038
nuclear exportGO:0051168690.038
negative regulation of cellular protein metabolic processGO:00322693530.036
inner ear morphogenesisGO:004247240.036
positive regulation of wnt signaling pathwayGO:0030177540.036
regulation of proteolysisGO:00301622930.036
nucleosome assemblyGO:0006334500.035
protein maturationGO:00516042330.035
oogenesisGO:004847720.034
inner ear developmentGO:004883980.034
regulation of mapk cascadeGO:00434082620.033
regulation of intracellular transportGO:00323861950.033
mitotic cell cycle processGO:19030472860.033
ubiquitin dependent protein catabolic processGO:00065112060.033
dna repairGO:00062811980.032
nucleosome organizationGO:0034728660.032
nerve developmentGO:002167540.032
central nervous system developmentGO:00074171230.032
cellular response to nitrogen compoundGO:19016991440.032
regulation of establishment of protein localizationGO:00702012420.032
regulation of intracellular protein transportGO:00331571230.032
positive regulation of meiotic cell cycleGO:005144620.032
transmembrane transportGO:00550853990.032
positive regulation of epithelial cell proliferationGO:0050679650.032
sensory perception of soundGO:0007605370.032
multicellular organismal agingGO:001025930.031
segmentationGO:003528240.031
cation transmembrane transportGO:00986552380.031
kidney developmentGO:0001822530.031
embryo developmentGO:00097901230.031
metal ion transportGO:00300012720.031
regulation of homeostatic processGO:00328441210.030
pattern specification processGO:0007389430.030
mapk cascadeGO:00001652880.030
head developmentGO:00603221080.030
cytoskeleton dependent intracellular transportGO:0030705210.029
cellular amino acid metabolic processGO:00065201160.029
cell divisionGO:00513011680.029
modification dependent macromolecule catabolic processGO:00436322120.029
neuromuscular junction developmentGO:000752830.029
neurological system processGO:00508771630.029
tissue morphogenesisGO:0048729960.029
regulation of protein catabolic processGO:00421761550.029
regulation of dna metabolic processGO:00510521530.028
microtubule based transportGO:0010970210.028
positive regulation of developmental processGO:00510943140.028
nucleoside monophosphate catabolic processGO:00091251590.028
response to nitrogen compoundGO:19016981840.028
negative regulation of protein processingGO:00109551420.028
positive regulation of transportGO:00510503360.027
renal system developmentGO:0072001630.027
negative regulation of multicellular organismal processGO:00512413170.027
epithelial cell differentiationGO:00308551410.027
proteolysis involved in cellular protein catabolic processGO:00516032440.026
double strand break repairGO:00063021010.026
regulation of cellular protein catabolic processGO:1903362960.026
dephosphorylationGO:00163112090.026
sensory perception of mechanical stimulusGO:0050954370.026
spindle organizationGO:0007051530.026
ras protein signal transductionGO:0007265730.026
protein processingGO:00164852260.026
cell morphogenesis involved in neuron differentiationGO:0048667440.026
canonical wnt signaling pathwayGO:00600701160.025
protein modification by small protein conjugationGO:00324463420.025
epithelial cell proliferationGO:00506731280.025
regulation of stress activated protein kinase signaling cascadeGO:0070302850.025
regulation of cell morphogenesisGO:00226041530.025
spermatid differentiationGO:004851540.025
regulation of vesicle mediated transportGO:00606271300.025
meiosis iGO:000712740.025
sensory perception of chemical stimulusGO:0007606380.025
nitrogen compound transportGO:00717051910.024
smoothened signaling pathwayGO:0007224140.024
regulation of receptor mediated endocytosisGO:0048259320.024
intrinsic apoptotic signaling pathwayGO:00971931270.024
regulation of endocytosisGO:0030100720.024
response to oxygen containing compoundGO:19017003690.024
chromatin remodelingGO:0006338550.024
cation transportGO:00068123310.024
hindbrain developmentGO:003090230.024
negative regulation of cell cycleGO:00457861930.024
chromosome segregationGO:00070591140.024
protein ubiquitinationGO:00165673140.023
regulation of protein transportGO:00512232130.023
axon developmentGO:0061564340.023
sensory perceptionGO:00076001030.023
signal transduction by phosphorylationGO:00230142970.023
regulation of metal ion transportGO:00109591200.023
apoptotic signaling pathwayGO:00971902680.023
meiotic chromosome segregationGO:004513240.023
dna packagingGO:0006323770.023
blastoderm segmentationGO:000735020.023
ion transmembrane transportGO:00342203380.023
negative regulation of mitotic cell cycleGO:00459301020.023
negative regulation of phosphorus metabolic processGO:00105632670.023
regulation of transferase activityGO:00513383550.023
positive regulation of transferase activityGO:00513472270.022
membrane organizationGO:00610242920.022
protein dephosphorylationGO:0006470810.022
rna splicingGO:00083801310.022
dna replication independent nucleosome assemblyGO:0006336270.022
post embryonic developmentGO:000979120.022
sensory organ developmentGO:0007423520.022
cellular macromolecular complex assemblyGO:00346223240.022
single organismal cell cell adhesionGO:00163371480.022
nuclear divisionGO:00002801280.022
regulation of ion homeostasisGO:2000021730.022
negative regulation of intracellular signal transductionGO:19025321830.022
mitotic cell cycle phase transitionGO:00447721620.022
dna replication independent nucleosome organizationGO:0034724270.021
regulation of transmembrane transporter activityGO:0022898740.021
nuclear transportGO:00511691790.021
reactive oxygen species biosynthetic processGO:190340940.021
regulation of membrane potentialGO:0042391950.021
regulation of cell cycle phase transitionGO:19019871260.020
regulation of chromosome organizationGO:00330441030.020
motor neuron axon guidanceGO:000804520.020
forebrain developmentGO:0030900260.020
cellular amine metabolic processGO:0044106410.020
negative regulation of catalytic activityGO:00430863350.020
maintenance of locationGO:00512351120.020
morphogenesis of embryonic epitheliumGO:001633140.020
positive regulation of dna metabolic processGO:0051054730.020
vesicle mediated transportGO:00161923710.020
amine metabolic processGO:0009308440.020
regulation of cellular amino acid metabolic processGO:000652160.019
regulation of kinase activityGO:00435493140.019
protein catabolic processGO:00301633250.019
regulation of cell projection organizationGO:00313441070.019
heart developmentGO:0007507950.019
negative regulation of cellular amino acid metabolic processGO:004576320.019
single organism cell adhesionGO:00986021790.019
single organism membrane organizationGO:00448022680.019
ribonucleoside triphosphate catabolic processGO:00092033910.019
spindle assembly involved in mitosisGO:0090307120.019
regulation of cellular component biogenesisGO:00440872810.018
cellular protein catabolic processGO:00442572610.018
positive regulation of chromosome organizationGO:2001252410.018
skin developmentGO:0043588760.018
double strand break repair via homologous recombinationGO:0000724500.018
endocytosisGO:00068971590.018
chordate embryonic developmentGO:0043009340.018
vasculature developmentGO:00019441810.018
small gtpase mediated signal transductionGO:0007264780.018
neuron projection morphogenesisGO:0048812500.018
morphogenesis of an epitheliumGO:0002009600.018
negative regulation of proteolysisGO:00458611320.018
positive regulation of dna replicationGO:0045740350.018
negative regulation of wnt signaling pathwayGO:0030178690.018
positive regulation of cell proliferationGO:00082843010.017
mitochondrion organizationGO:00070051560.017
lipid metabolic processGO:00066293810.017
positive regulation of phosphorylationGO:00423273940.017
positive regulation of purine nucleotide metabolic processGO:19005442270.017
regulation of cellular amine metabolic processGO:0033238110.017
positive regulation of kinase activityGO:00336742040.017
sequestering of calcium ionGO:0051208170.017
negative regulation of phosphorylationGO:00423261740.017
action potentialGO:0001508340.017
regulation of nucleoside metabolic processGO:00091182090.017
regulation of jnk cascadeGO:0046328730.017
recombinational repairGO:0000725500.017
monovalent inorganic cation transportGO:00156721280.017
positive regulation of cellular catabolic processGO:00313312840.017
oocyte developmentGO:004859910.017
regulation of cytoplasmic transportGO:19036491490.017
organelle localizationGO:0051640840.017
negative regulation of protein maturationGO:19033181420.017
peptidyl tyrosine dephosphorylationGO:0035335360.016
response to biotic stimulusGO:00096072760.016
positive regulation of gtpase activityGO:00435471660.016
establishment of protein localization to membraneGO:00901501210.016
negative regulation of cell proliferationGO:00082852280.016
locomotory behaviorGO:000762610.016
proteasomal protein catabolic processGO:00104981760.016
regulation of anatomical structure morphogenesisGO:00226032860.016
response to growth factorGO:00708482050.016
organonitrogen compound biosynthetic processGO:19015662000.016
regulation of sister chromatid segregationGO:0033045270.016
dna damage response signal transduction by p53 class mediatorGO:0030330440.016
cellular ketone metabolic processGO:0042180800.016
protein dna complex assemblyGO:0065004640.016
negative regulation of cellular catabolic processGO:0031330830.016
positive regulation of reactive oxygen species biosynthetic processGO:190342820.015
positive regulation of catabolic processGO:00098963100.015
regulation of stress activated mapk cascadeGO:0032872840.015
cytoplasmic transportGO:00164823790.015
regulation of rab gtpase activityGO:0032313390.015
telomere organizationGO:0032200330.015
oocyte differentiationGO:000999420.015
axonogenesisGO:0007409310.015
mitotic sister chromatid segregationGO:0000070530.015
protein polyubiquitinationGO:00002091100.015
rna processingGO:00063962550.015
regulation of dna replicationGO:0006275680.015
mitotic sister chromatid separationGO:0051306180.015
cellular response to endogenous stimulusGO:00714953360.015
nucleocytoplasmic transportGO:00069131760.014
specification of symmetryGO:0009799160.014
reactive oxygen species metabolic processGO:0072593750.014
short term memoryGO:000761410.014
dna duplex unwindingGO:0032508300.014
dna geometric changeGO:0032392320.014
regulation of action potentialGO:009890020.014
protein export from nucleusGO:0006611290.014
regulation of cellular component movementGO:00512703340.014
cell adhesionGO:00071553250.014
positive regulation of nucleotide catabolic processGO:00308131850.014
receptor mediated endocytosisGO:0006898840.014
epidermis developmentGO:0008544590.014
gtp catabolic processGO:00061842370.014
single organism cellular localizationGO:19025803320.014
positive regulation of purine nucleotide catabolic processGO:00331231850.014
regulation of cellular ketone metabolic processGO:0010565500.014
cerebellum developmentGO:002154920.014
regulation of sodium ion transmembrane transporter activityGO:2000649170.014
modification dependent protein catabolic processGO:00199412090.014
regulation of purine nucleotide metabolic processGO:19005422640.014
sister chromatid cohesionGO:0007062240.013
signal transduction in response to dna damageGO:0042770570.013
negative regulation of phosphate metabolic processGO:00459362670.013
regulation of growthGO:00400081650.013
protein autophosphorylationGO:00467771230.013
regulation of reactive oxygen species biosynthetic processGO:190342630.013
negative regulation of transportGO:00510511760.013
multi organism cellular processGO:00447641560.013
mitotic spindle elongationGO:000002240.013
positive regulation of homeostatic processGO:0032846470.013
inorganic ion transmembrane transportGO:00986602310.013
determination of bilateral symmetryGO:0009855150.013
immune system developmentGO:00025201950.013
jnk cascadeGO:0007254800.013
neural tube developmentGO:002191590.013
regulation of cell developmentGO:00602841610.013
cellular response to growth factor stimulusGO:00713631970.013
stem cell developmentGO:0048864690.013
regenerationGO:003109940.013
regulation of gtp catabolic processGO:00331241800.013
regulation of nucleotide metabolic processGO:00061402690.013
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.013
response to inorganic substanceGO:00100351270.013
cell cycle phase transitionGO:00447701730.013
regulation of sodium ion transportGO:0002028240.012
calcium ion homeostasisGO:00550741220.012
blood vessel morphogenesisGO:00485141620.012
positive regulation of protein phosphorylationGO:00019343130.012
sequestering of metal ionGO:0051238240.012
growthGO:00400072020.012
cellular calcium ion homeostasisGO:00068741170.012
positive regulation of hydrolase activityGO:00513453310.012
divalent inorganic cation transportGO:00725111580.012
photoreceptor cell differentiationGO:004653020.012
leukocyte activationGO:00453211640.012
metaphase anaphase transition of cell cycleGO:0044784210.012
actin cytoskeleton organizationGO:00300362070.012
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.012
neuron remodelingGO:001632220.012
intracellular protein transportGO:00068862700.012
regulation of purine nucleotide catabolic processGO:00331212050.012
embryonic epithelial tube formationGO:000183840.012
dna dependent dna replication maintenance of fidelityGO:0045005140.012
divalent metal ion transportGO:00708381520.012
cellular response to abiotic stimulusGO:00712141170.012
brain developmentGO:0007420970.012
response to abiotic stimulusGO:00096283360.012
Mouse
secretion by cellGO:00329402260.012
regulation of protein processingGO:00706131500.012
sister chromatid segregationGO:0000819540.012
hematopoietic or lymphoid organ developmentGO:00485341860.012
developmental process involved in reproductionGO:0003006660.012
regulation of cellular response to stressGO:00801352440.012
cell fate determinationGO:000170930.012
negative regulation of organelle organizationGO:00106391260.012
translationGO:00064121320.012
lipid localizationGO:00108761060.012
response to axon injuryGO:004867810.012
positive regulation of endocytosisGO:0045807420.012
cellular homeostasisGO:00197251960.011
posttranscriptional regulation of gene expressionGO:00106082130.011
reproductive processGO:00224141060.011
cell substrate adhesionGO:00315891320.011
purine ribonucleoside metabolic processGO:00461284370.011
centrosome organizationGO:0051297580.011
oxidation reduction processGO:00551143960.011
metencephalon developmentGO:002203720.011
regulation of mitotic cell cycle phase transitionGO:19019901180.011
response to other organismGO:00517072610.011
humoral immune responseGO:0006959490.011
regionalizationGO:0003002290.011
establishment of organelle localizationGO:0051656590.011
negative regulation of cell cycle processGO:00109481210.011
membrane depolarization during action potentialGO:0086010100.011
positive regulation of cell differentiationGO:00455972110.011
cellular metal ion homeostasisGO:00068751460.011
associative learningGO:000830610.011
positive regulation of cell divisionGO:0051781590.011
reactive nitrogen species metabolic processGO:200105730.011
negative regulation of cellular amine metabolic processGO:003323930.011
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377890.011
positive regulation of cellular amine metabolic processGO:003324070.011
negative regulation of programmed cell deathGO:00430693210.011
positive regulation of cellular component biogenesisGO:00440891580.011
defense responseGO:00069523150.011
response to external biotic stimulusGO:00432072610.011
cell growthGO:00160491600.011
positive regulation of chromatin assembly or disassemblyGO:004579920.010
cellular cation homeostasisGO:00300031630.010
positive regulation of reactive oxygen species metabolic processGO:2000379240.010
signal transduction by p53 class mediatorGO:0072331720.010
cellular chemical homeostasisGO:00550821800.010
reciprocal meiotic recombinationGO:000713140.010
dna recombinationGO:0006310770.010
positive regulation of cell developmentGO:0010720920.010
innate immune responseGO:00450871780.010
protein homooligomerizationGO:00512601000.010
regulation of ion transmembrane transporter activityGO:0032412720.010
protein localization to membraneGO:00726571600.010
cytokine productionGO:00018162470.010
secretionGO:00469032540.010

NEK1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
meckel syndromeDOID:0050778110.281
sensory system diseaseDOID:00501552030.059
nervous system diseaseDOID:8634310.059
eye and adnexa diseaseDOID:14921500.059
joubert syndromeDOID:0050777180.035
eye diseaseDOID:56141490.033
retinal diseaseDOID:56791180.030
immune system diseaseDOID:29141550.024
disease of cellular proliferationDOID:145661740.019
hematopoietic system diseaseDOID:741000.016
cancerDOID:1621670.015
central nervous system diseaseDOID:3311860.014
neurodegenerative diseaseDOID:12891020.014
disease of metabolismDOID:00146672950.012