Homo sapiens

12 known processes

PHEX

phosphate regulating endopeptidase homolog, X-linked

(Aliases: HPDR,PEX,HPDR1,XLH,HYP1,LXHR,HYP)

PHEX biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201160.063
post embryonic developmentGO:000979120.060
cellular ketone metabolic processGO:0042180800.056
regulation of cellular amine metabolic processGO:0033238110.054
amine metabolic processGO:0009308440.052
regulation of cellular ketone metabolic processGO:0010565500.049
positive regulation of cellular amine metabolic processGO:003324070.045
cellular amine metabolic processGO:0044106410.045
regulation of cellular amino acid metabolic processGO:000652160.043
positive regulation of cellular amino acid metabolic processGO:004576430.041
multicellular organismal agingGO:001025930.040
positive regulation of phosphorylationGO:00423273940.039
determination of adult lifespanGO:000834020.037
immune responseGO:00069553070.037
negative regulation of catalytic activityGO:00430863350.035
defense responseGO:00069523150.035
neuromuscular junction developmentGO:000752830.034
female gamete generationGO:000729220.033
positive regulation of hydrolase activityGO:00513453310.033
system processGO:00030083490.033
Human
cytoplasmic transportGO:00164823790.033
positive regulation of transportGO:00510503360.032
purine ribonucleoside metabolic processGO:00461284370.032
lipid metabolic processGO:00066293810.031
membrane organizationGO:00610242920.031
negative regulation of protein metabolic processGO:00512483910.031
cellular lipid metabolic processGO:00442553030.030
oogenesisGO:004847720.030
purine ribonucleotide catabolic processGO:00091544040.030
ribonucleoside catabolic processGO:00424544060.030
locomotory behaviorGO:000762610.030
signal transduction by phosphorylationGO:00230142970.030
negative regulation of cellular protein metabolic processGO:00322693530.030
regulation of protein kinase activityGO:00458592890.030
organophosphate catabolic processGO:00464344300.030
single organism cellular localizationGO:19025803320.029
cell adhesionGO:00071553250.029
mapk cascadeGO:00001652880.029
purine ribonucleoside triphosphate metabolic processGO:00092054110.029
nucleoside triphosphate metabolic processGO:00091414220.028
purine containing compound catabolic processGO:00725234110.028
ribonucleoside triphosphate metabolic processGO:00091994120.028
regulation of kinase activityGO:00435493140.028
glycosyl compound catabolic processGO:19016584130.028
cellular response to dna damage stimulusGO:00069743790.028
regulation of cell cycleGO:00517263930.028
regulation of transferase activityGO:00513383550.028
segmentationGO:003528240.027
negative regulation of apoptotic processGO:00430663160.027
cation transportGO:00068123310.027
regulation of secretionGO:00510461940.027
protein processingGO:00164852260.027
Human
negative regulation of programmed cell deathGO:00430693210.027
single organism membrane organizationGO:00448022680.027
positive regulation of protein phosphorylationGO:00019343130.027
purine nucleoside triphosphate metabolic processGO:00091444120.027
response to abiotic stimulusGO:00096283360.027
negative regulation of cell deathGO:00605483450.026
nucleoside triphosphate catabolic processGO:00091433940.026
nucleotide catabolic processGO:00091664080.026
actin filament based processGO:00300292240.026
positive regulation of immune system processGO:00026842830.026
purine ribonucleoside triphosphate catabolic processGO:00092073910.026
ribonucleotide catabolic processGO:00092614050.026
regulation of cellular component movementGO:00512703340.025
nucleoside phosphate catabolic processGO:19012924120.025
regulation of proteolysisGO:00301622930.025
purine nucleotide catabolic processGO:00061954050.025
regulation of protein localizationGO:00328802960.025
ribonucleoside triphosphate catabolic processGO:00092033910.025
protein maturationGO:00516042330.025
Human
innate immune responseGO:00450871780.025
purine nucleoside triphosphate catabolic processGO:00091463920.024
positive regulation of cellular component organizationGO:00511303760.024
purine nucleoside catabolic processGO:00061523980.024
ras protein signal transductionGO:0007265730.024
vesicle mediated transportGO:00161923710.024
negative regulation of phosphorus metabolic processGO:00105632670.024
biological adhesionGO:00226103310.024
circulatory system developmentGO:00723592620.024
Human
cardiovascular system developmentGO:00723582620.024
Human
cell morphogenesisGO:00009022960.024
memoryGO:000761330.024
response to other organismGO:00517072610.024
carbohydrate metabolic processGO:00059752070.023
nucleoside catabolic processGO:00091644080.023
cell activationGO:00017752130.023
nervous system developmentGO:00073992930.023
cellular component morphogenesisGO:00329893140.023
positive regulation of cell differentiationGO:00455972110.023
response to external biotic stimulusGO:00432072610.023
regulation of nucleotide metabolic processGO:00061402690.023
response to biotic stimulusGO:00096072760.022
purine ribonucleoside catabolic processGO:00461303980.022
cellular macromolecule catabolic processGO:00442653800.022
enzyme linked receptor protein signaling pathwayGO:00071673030.022
regenerationGO:003109940.022
secretionGO:00469032540.022
regulation of establishment of protein localizationGO:00702012420.022
organic hydroxy compound metabolic processGO:19016151470.022
mitotic cell cycleGO:00002783260.022
blastoderm segmentationGO:000735020.022
apoptotic signaling pathwayGO:00971902680.021
positive regulation of catabolic processGO:00098963100.021
rho protein signal transductionGO:0007266260.021
intracellular protein transportGO:00068862700.021
single organism carbohydrate metabolic processGO:00447231930.021
epithelium developmentGO:00604292270.021
dephosphorylationGO:00163112090.021
protein localization to organelleGO:00333652800.021
protein catabolic processGO:00301633250.021
anterior posterior axis specificationGO:000994820.021
anatomical structure formation involved in morphogenesisGO:00486462840.021
regulation of mapk cascadeGO:00434082620.021
oxidation reduction processGO:00551143960.021
oocyte developmentGO:004859910.021
positive regulation of protein kinase activityGO:00458601900.021
negative regulation of cell proliferationGO:00082852280.021
cellular macromolecular complex assemblyGO:00346223240.021
negative regulation of phosphate metabolic processGO:00459362670.021
positive regulation of cell proliferationGO:00082843010.021
associative learningGO:000830610.021
positive regulation of mapk cascadeGO:00434101900.021
epidermis morphogenesisGO:004873030.021
oocyte differentiationGO:000999420.021
regulation of cellular response to stressGO:00801352440.021
regulation of purine nucleotide metabolic processGO:19005422640.021
positive regulation of transferase activityGO:00513472270.020
small molecule biosynthetic processGO:00442831570.020
blood vessel developmentGO:00015681720.020
morphogenesis of embryonic epitheliumGO:001633140.020
positive regulation of cellular catabolic processGO:00313312840.020
regulation of cell cycle processGO:00105642660.020
positive regulation of cell deathGO:00109422630.020
chemical homeostasisGO:00488783060.020
negative regulation of hydrolase activityGO:00513461820.020
cell projection organizationGO:00300302520.020
metal ion transportGO:00300012720.020
small gtpase mediated signal transductionGO:0007264780.019
regulation of anatomical structure morphogenesisGO:00226032860.019
regulation of endopeptidase activityGO:00525481700.019
regulation of cell differentiationGO:00455953930.019
regulation of cytokine productionGO:00018172320.019
regulation of cell motilityGO:20001452990.019
organophosphate biosynthetic processGO:00904071630.019
positive regulation of programmed cell deathGO:00430682490.019
organonitrogen compound biosynthetic processGO:19015662000.019
regulation of peptidase activityGO:00525471800.019
endomembrane system organizationGO:00102561960.019
regulation of intracellular transportGO:00323861950.019
nitrogen compound transportGO:00717051910.019
negative regulation of cellular amino acid metabolic processGO:004576320.018
regulation of locomotionGO:00400123290.018
epithelial cell differentiationGO:00308551410.018
mitotic cell cycle processGO:19030472860.018
anterior posterior axis specification embryoGO:000859520.018
motor neuron axon guidanceGO:000804520.018
cellular homeostasisGO:00197251960.018
secretion by cellGO:00329402260.018
regulation of cell migrationGO:00303342890.018
positive regulation of apoptotic processGO:00430652460.018
regulation of protein serine threonine kinase activityGO:00719001790.018
protein targetingGO:00066051870.018
negative regulation of cellular amine metabolic processGO:003323930.018
peripheral nervous system developmentGO:000742220.018
gtp catabolic processGO:00061842370.018
cell developmentGO:00484683280.018
negative regulation of cell cycleGO:00457861930.018
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.018
guanosine containing compound catabolic processGO:19010692390.018
maintenance of locationGO:00512351120.018
regulation of protein transportGO:00512232130.018
regulation of cellular component biogenesisGO:00440872810.018
salivary gland morphogenesisGO:000743540.018
cellular cation homeostasisGO:00300031630.018
positive regulation of developmental processGO:00510943140.017
positive regulation of nucleotide metabolic processGO:00459812300.017
cellular protein catabolic processGO:00442572610.017
response to lipidGO:00339932060.017
gtp metabolic processGO:00460392390.017
regulation of immune responseGO:00507762010.017
g protein coupled receptor signaling pathwayGO:00071862070.017
limbic system developmentGO:002176130.017
cellular response to endogenous stimulusGO:00714953360.017
positive regulation of kinase activityGO:00336742040.017
proteolysis involved in cellular protein catabolic processGO:00516032440.017
spermatid differentiationGO:004851540.017
regulation of response to external stimulusGO:00321012220.017
negative regulation of protein modification processGO:00314002000.017
embryonic epithelial tube formationGO:000183840.017
transmembrane transportGO:00550853990.017
negative regulation of developmental processGO:00510932470.017
cytokine productionGO:00018162470.016
specification of organ identityGO:001009230.016
response to oxygen containing compoundGO:19017003690.016
tripartite regional subdivisionGO:000735120.016
organelle assemblyGO:00709251760.016
response to cytokineGO:00340972320.016
negative regulation of intracellular signal transductionGO:19025321830.016
response to organic cyclic compoundGO:00140702040.016
negative regulation of multicellular organismal processGO:00512413170.016
ion homeostasisGO:00508012300.016
microtubule based processGO:00070172100.016
reactive oxygen species biosynthetic processGO:190340940.016
cation homeostasisGO:00550801890.016
positive regulation of purine nucleotide metabolic processGO:19005442270.016
negative regulation of cellular component organizationGO:00511292350.016
divalent inorganic cation transportGO:00725111580.016
regulation of nucleoside metabolic processGO:00091182090.016
blood vessel morphogenesisGO:00485141620.016
guanosine containing compound metabolic processGO:19010682440.016
cellular chemical homeostasisGO:00550821800.016
protein localization to membraneGO:00726571600.016
photoreceptor cell differentiationGO:004653020.016
response to radiationGO:00093141510.016
monocarboxylic acid metabolic processGO:00327871850.016
regulation of nucleotide catabolic processGO:00308112050.016
regulation of sequence specific dna binding transcription factor activityGO:00510902110.016
adult locomotory behaviorGO:000834410.016
response to axon injuryGO:004867810.016
chromatin organizationGO:00063253510.016
rhythmic behaviorGO:000762220.016
regulation of cell adhesionGO:00301551660.016
lipid biosynthetic processGO:00086101770.015
single organism cell adhesionGO:00986021790.015
regulation of secretion by cellGO:19035301770.015
metal ion homeostasisGO:00550651690.015
lung alveolus developmentGO:004828640.015
calcium ion transportGO:00068161470.015
organ formationGO:004864530.015
carbohydrate derivative biosynthetic processGO:19011372070.015
regulation of purine nucleotide catabolic processGO:00331212050.015
protein modification by small protein conjugationGO:00324463420.015
inner ear morphogenesisGO:004247240.015
neurotransmitter secretionGO:000726940.015
organic acid biosynthetic processGO:0016053970.015
negative regulation of protein processingGO:00109551420.015
visual behaviorGO:000763220.015
vasculature developmentGO:00019441810.015
cell divisionGO:00513011680.015
regulation of mitotic cell cycleGO:00073461890.015
reactive oxygen species metabolic processGO:0072593750.015
regulation of protein maturationGO:19033171500.015
positive regulation of cytokine productionGO:00018191670.015
cardiac muscle cell contractionGO:008600340.015
covalent chromatin modificationGO:00165692540.015
posttranscriptional regulation of gene expressionGO:00106082130.015
protein ubiquitinationGO:00165673140.015
carboxylic acid biosynthetic processGO:0046394970.015
response to woundingGO:00096111680.015
compound eye developmentGO:004874910.015
dna repairGO:00062811980.015
spermatid developmentGO:000728640.015
regulation of protein processingGO:00706131500.015
regulation of synaptic plasticityGO:004816730.015
circadian behaviorGO:004851220.015
chromatin modificationGO:00165682980.015
hindbrain developmentGO:003090230.015
neurological system processGO:00508771630.015
establishment of protein localization to organelleGO:00725941720.015
cellular response to oxygen containing compoundGO:19017012760.015
purine ribonucleoside monophosphate metabolic processGO:00091671860.015
negative regulation of phosphorylationGO:00423261740.015
nuclear transportGO:00511691790.014
cellular divalent inorganic cation homeostasisGO:00725031280.014
reactive nitrogen species metabolic processGO:200105730.014
single organismal cell cell adhesionGO:00163371480.014
negative regulation of protein maturationGO:19033181420.014
angiogenesisGO:00015251470.014
divalent metal ion transportGO:00708381520.014
purine nucleoside monophosphate metabolic processGO:00091261860.014
regulation of cysteine type endopeptidase activityGO:20001161270.014
epithelium migrationGO:00901321190.014
cellular metal ion homeostasisGO:00068751460.014
cellular protein complex assemblyGO:00436231880.014
regulation of dna metabolic processGO:00510521530.014
growthGO:00400072020.014
release of cytoplasmic sequestered nf kappabGO:000858840.014
regulation of neural precursor cell proliferationGO:200017740.014
positive regulation of hormone biosynthetic processGO:004688640.014
actin cytoskeleton organizationGO:00300362070.014
rna processingGO:00063962550.014
ion transmembrane transportGO:00342203380.014
positive regulation of proteolysisGO:00458621420.014
positive regulation of purine nucleotide catabolic processGO:00331231850.014
syncytium formation by plasma membrane fusionGO:000076820.014
positive regulation of protein transportGO:00512221350.014
synaptic transmission involved in micturitionGO:006008420.014
sensory perceptionGO:00076001030.014
actin mediated cell contractionGO:0070252120.014
matingGO:000761810.014
chemotaxisGO:00069351570.014
mitochondrion organizationGO:00070051560.014
taxisGO:00423301570.014
anion transportGO:00068201610.014
positive regulation of nucleoside metabolic processGO:00459791860.014
negative regulation of proteolysisGO:00458611320.014
histone modificationGO:00165702510.014
glycoprotein metabolic processGO:00091001100.014
sequestering of metal ionGO:0051238240.014
nucleocytoplasmic transportGO:00069131760.014
stem cell divisionGO:001714520.014
thymus developmentGO:004853830.013
cell cycle phase transitionGO:00447701730.013
alcohol metabolic processGO:00060661140.013
epithelial cell migrationGO:00106311190.013
modification dependent protein catabolic processGO:00199412090.013
plasma membrane organizationGO:00070091150.013
regulation of reactive oxygen species biosynthetic processGO:190342630.013
modification dependent macromolecule catabolic processGO:00436322120.013
response to fungusGO:000962040.013
embryonic forelimb morphogenesisGO:003511540.013
calcium ion homeostasisGO:00550741220.013
ribonucleoside monophosphate metabolic processGO:00091611870.013
central nervous system developmentGO:00074171230.013
immune effector processGO:00022521590.013
proteasomal protein catabolic processGO:00104981760.013
cell fate determinationGO:000170930.013
regulation of vasculature developmentGO:1901342970.013
actin filament based movementGO:0030048170.013
nucleoside monophosphate metabolic processGO:00091231910.013
negative regulation of acetylcholine gated cation channel activityGO:190304910.013
cellular calcium ion homeostasisGO:00068741170.013
regulation of meiotic cell cycleGO:005144540.013
atp metabolic processGO:00460341760.013
regulation of cell developmentGO:00602841610.013
regulation of protein catabolic processGO:00421761550.013
sensory perception of painGO:001923340.013
response to growth factorGO:00708482050.013
cell projection assemblyGO:00300311260.013
neuroblast proliferationGO:000740540.013
positive regulation of cellular component biogenesisGO:00440891580.013
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.013
tissue migrationGO:00901301190.013
regulation of reactive oxygen species metabolic processGO:2000377410.013
negative regulation of protein phosphorylationGO:00019331400.013
regulation of gtpase activityGO:00430871800.013
cell growthGO:00160491600.013
glial cell migrationGO:000834740.013
regulation of defense responseGO:00313471540.013
cell part morphogenesisGO:00329901370.013
nerve developmentGO:002167540.013
neurogenesisGO:00220081690.013
regulation of apoptotic signaling pathwayGO:20012331750.013
endocytosisGO:00068971590.013
forelimb morphogenesisGO:003513640.013
sequestering of calcium ionGO:0051208170.013
tissue regenerationGO:004224630.013
negative regulation of cell cycle processGO:00109481210.013
positive regulation of cell migrationGO:00303351720.012
regulation of cytoskeleton organizationGO:00514931770.012
ubiquitin dependent protein catabolic processGO:00065112060.012
positive regulation of nucleotide catabolic processGO:00308131850.012
microtubule cytoskeleton organizationGO:00002261760.012
establishment of protein localization to membraneGO:00901501210.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.012
regulation of gtp catabolic processGO:00331241800.012
negative regulation of transferase activityGO:00513481240.012
regulation of cytoplasmic transportGO:19036491490.012
regulation of multi organism processGO:00439001570.012
sex determinationGO:000753030.012
positive regulation of organelle organizationGO:00106381950.012
positive regulation of reactive oxygen species metabolic processGO:2000379240.012
hair follicle morphogenesisGO:003106920.012
cellular response to growth factor stimulusGO:00713631970.012
primary neural tube formationGO:001402030.012
regulation of neurotransmitter secretionGO:004692830.012
regulation of dephosphorylationGO:0035303960.012
cellular ion homeostasisGO:00068731680.012
activation of protein kinase activityGO:0032147900.012
positive regulation of cellular component movementGO:00512721810.012
regulation of cell growthGO:00015581350.012
cellular modified amino acid metabolic processGO:0006575640.012
mitotic cell cycle phase transitionGO:00447721620.012
multi organism cellular processGO:00447641560.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
regulation of acetylcholine gated cation channel activityGO:190304810.012
leukocyte migrationGO:00509001070.012
hindlimb morphogenesisGO:003513720.012
symbiosis encompassing mutualism through parasitismGO:00444031560.012
visual learningGO:000854210.012
long term memoryGO:000761620.012
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.012
positive regulation of secretionGO:00510471160.012
head developmentGO:00603221080.012
micturitionGO:006007330.012
cell projection morphogenesisGO:00488581290.012
negative regulation of synaptic transmissionGO:005080520.012
negative regulation of transportGO:00510511760.012
t cell differentiation in thymusGO:003307740.012
negative regulation of glomerulus developmentGO:009019420.012
positive regulation of protein serine threonine kinase activityGO:00719021190.012
regulation of ion transportGO:00432691890.012
response to organonitrogen compoundGO:00102431560.012
positive regulation of cell motilityGO:20001471770.012
regulation of intracellular protein transportGO:00331571230.012
anatomical structure homeostasisGO:00602491000.012
neural tube formationGO:000184130.012
immune system developmentGO:00025201950.012
epithelial cell proliferationGO:00506731280.012
positive regulation of synaptic transmissionGO:005080640.012
meiotic chromosome segregationGO:004513240.012
protein oligomerizationGO:00512591730.012
peptidyl tyrosine modificationGO:00182121700.011
metencephalon developmentGO:002203720.011
positive regulation of secretion by cellGO:19035321080.011
wnt signaling pathwayGO:00160551560.011
regulation of vesicle mediated transportGO:00606271300.011
regulation of map kinase activityGO:00434051080.011
positive regulation of immune responseGO:00507781590.011
cellular response to lipidGO:00713961270.011
neural tube closureGO:000184330.011
positive regulation of steroid hormone biosynthetic processGO:009003120.011
postsynaptic membrane organizationGO:000194120.011
vasodilationGO:004231140.011
organ morphogenesisGO:00098871470.011
peptidyl tyrosine phosphorylationGO:00181081700.011
intrinsic apoptotic signaling pathwayGO:00971931270.011
sulfur compound metabolic processGO:00067901010.011
response to virusGO:00096151260.011
negative regulation of cell motilityGO:20001461040.011
protein autophosphorylationGO:00467771230.011
monocarboxylic acid biosynthetic processGO:0072330670.011
forebrain generation of neuronsGO:002187230.011
activation of immune responseGO:00022531140.011
negative regulation of organelle organizationGO:00106391260.011
regulation of angiogenesisGO:0045765920.011
developmental programmed cell deathGO:001062330.011
sensory perception of smellGO:000760820.011
hematopoietic or lymphoid organ developmentGO:00485341860.011
leukocyte activationGO:00453211640.011
rna interferenceGO:001624640.011
melanin metabolic processGO:000658210.011
lipid localizationGO:00108761060.011
negative regulation of locomotionGO:00400131180.011
organelle fissionGO:00482851490.011
protein importGO:00170381300.011
response to nitrogen compoundGO:19016981840.011
mitotic nuclear divisionGO:00070671190.011
organic hydroxy compound biosynthetic processGO:1901617710.011
somatic muscle developmentGO:000752510.011
cation transmembrane transportGO:00986552380.011
generation of neuronsGO:00486991520.011
cellular response to organic cyclic compoundGO:00714071270.011
glycoprotein biosynthetic processGO:0009101910.011
axon regenerationGO:003110310.011
patterning of blood vesselsGO:000156920.011
tube closureGO:006060630.011
somatic stem cell divisionGO:004810310.011
positive regulation of gtp catabolic processGO:00331261660.011
negative regulation of immune system processGO:00026831360.011
prostate gland developmentGO:003085030.011
positive regulation of organic acid transportGO:003289230.011
nucleoside monophosphate catabolic processGO:00091251590.011
response to metal ionGO:0010038840.011
protein localization to nucleusGO:00345041360.011
interspecies interaction between organismsGO:00444191560.011
ossificationGO:00015031210.011
male genitalia developmentGO:003053910.011
serotonin transportGO:000683730.011
meiosis iGO:000712740.011
negative regulation of peptidase activityGO:0010466910.011
negative regulation of endopeptidase activityGO:0010951840.011
stress activated mapk cascadeGO:0051403930.011
phototransductionGO:000760230.011

PHEX disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.035
Human
disease of metabolismDOID:00146672950.029
central nervous system diseaseDOID:3311860.027
nervous system diseaseDOID:8634310.027
sensory system diseaseDOID:00501552030.025
disease of cellular proliferationDOID:145661740.022
cancerDOID:1621670.021
eye and adnexa diseaseDOID:14921500.020
eye diseaseDOID:56141490.020
connective tissue diseaseDOID:651090.020
organ system cancerDOID:00506861640.020
immune system diseaseDOID:29141550.019
bone diseaseDOID:0080001880.019
inherited metabolic disorderDOID:6552420.018
retinal diseaseDOID:56791180.017
neurodegenerative diseaseDOID:12891020.016
muscle tissue diseaseDOID:661130.015
Human
muscular diseaseDOID:00800001140.015
Human
cardiovascular system diseaseDOID:12871060.014
Human
primary ciliary dyskinesiaDOID:9562270.013
heart diseaseDOID:114680.013
myopathyDOID:4231040.012
retinal degenerationDOID:8466890.012
disease of mental healthDOID:150700.012
brain diseaseDOID:936730.011
hematopoietic system diseaseDOID:741000.011
cardiomyopathyDOID:0050700500.011
intrinsic cardiomyopathyDOID:0060036500.011