Homo sapiens

6 known processes

LHPP

phospholysine phosphohistidine inorganic pyrophosphate phosphatase

(Aliases: HDHD2B,MGC142189,MGC142191,MGC117251,FLJ44846,FLJ46044)

LHPP biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
lipid metabolic processGO:00066293810.129
cellular lipid metabolic processGO:00442553030.110
cellular amino acid metabolic processGO:00065201160.071
lipid biosynthetic processGO:00086101770.064
cellular ketone metabolic processGO:0042180800.064
regulation of cellular ketone metabolic processGO:0010565500.055
post embryonic developmentGO:000979120.052
small molecule biosynthetic processGO:00442831570.051
regulation of cellular amino acid metabolic processGO:000652160.045
amine metabolic processGO:0009308440.044
response to oxygen containing compoundGO:19017003690.042
purine nucleoside triphosphate metabolic processGO:00091444120.042
regulation of cellular amine metabolic processGO:0033238110.042
oxidation reduction processGO:00551143960.041
monocarboxylic acid metabolic processGO:00327871850.041
cellular amine metabolic processGO:0044106410.040
metal ion transportGO:00300012720.039
cellular response to endogenous stimulusGO:00714953360.037
cellular response to oxygen containing compoundGO:19017012760.037
purine ribonucleoside metabolic processGO:00461284370.037
positive regulation of transportGO:00510503360.036
nucleotide catabolic processGO:00091664080.036
carboxylic acid biosynthetic processGO:0046394970.035
nucleoside phosphate catabolic processGO:19012924120.035
nucleoside triphosphate metabolic processGO:00091414220.034
ribonucleotide catabolic processGO:00092614050.034
ribonucleoside triphosphate metabolic processGO:00091994120.034
positive regulation of cellular amino acid metabolic processGO:004576430.034
organic acid biosynthetic processGO:0016053970.033
ribonucleoside catabolic processGO:00424544060.033
purine ribonucleoside triphosphate metabolic processGO:00092054110.032
determination of adult lifespanGO:000834020.031
glycerolipid metabolic processGO:00464861070.031
positive regulation of cellular amine metabolic processGO:003324070.031
organophosphate catabolic processGO:00464344300.030
purine containing compound catabolic processGO:00725234110.030
negative regulation of protein metabolic processGO:00512483910.030
carbohydrate metabolic processGO:00059752070.030
purine nucleotide catabolic processGO:00061954050.029
fatty acid metabolic processGO:00066311150.029
negative regulation of catalytic activityGO:00430863350.029
female gamete generationGO:000729220.029
chemical homeostasisGO:00488783060.029
multicellular organismal agingGO:001025930.029
locomotory behaviorGO:000762610.028
purine nucleoside catabolic processGO:00061523980.028
system processGO:00030083490.027
positive regulation of cellular catabolic processGO:00313312840.027
ribonucleoside triphosphate catabolic processGO:00092033910.027
oogenesisGO:004847720.027
purine nucleoside triphosphate catabolic processGO:00091463920.027
positive regulation of catabolic processGO:00098963100.027
single organism carbohydrate metabolic processGO:00447231930.026
ras protein signal transductionGO:0007265730.026
negative regulation of cellular protein metabolic processGO:00322693530.026
organonitrogen compound biosynthetic processGO:19015662000.026
regulation of cellular component biogenesisGO:00440872810.026
anion transportGO:00068201610.026
glycosyl compound catabolic processGO:19016584130.025
regulation of ion transportGO:00432691890.025
organophosphate biosynthetic processGO:00904071630.024
cellular macromolecular complex assemblyGO:00346223240.024
regulation of proteolysisGO:00301622930.024
purine ribonucleoside catabolic processGO:00461303980.024
small gtpase mediated signal transductionGO:0007264780.024
segmentationGO:003528240.023
regulation of anatomical structure morphogenesisGO:00226032860.023
nucleoside catabolic processGO:00091644080.023
cellular component morphogenesisGO:00329893140.023
purine ribonucleotide catabolic processGO:00091544040.023
nucleoside triphosphate catabolic processGO:00091433940.023
purine ribonucleoside triphosphate catabolic processGO:00092073910.023
positive regulation of hydrolase activityGO:00513453310.023
cell morphogenesisGO:00009022960.023
regulation of nucleoside metabolic processGO:00091182090.022
nitrogen compound transportGO:00717051910.022
regulation of nucleotide metabolic processGO:00061402690.022
maintenance of locationGO:00512351120.022
negative regulation of cellular component organizationGO:00511292350.022
response to abiotic stimulusGO:00096283360.022
cellular response to nitrogen compoundGO:19016991440.022
regulation of cellular component movementGO:00512703340.022
defense responseGO:00069523150.021
response to hormoneGO:00097251750.021
monocarboxylic acid biosynthetic processGO:0072330670.021
response to nitrogen compoundGO:19016981840.021
negative regulation of cell deathGO:00605483450.021
biological adhesionGO:00226103310.021
regulation of purine nucleotide catabolic processGO:00331212050.021
single organism membrane organizationGO:00448022680.020
positive regulation of cellular component organizationGO:00511303760.020
regulation of nucleotide catabolic processGO:00308112050.020
single organism cellular localizationGO:19025803320.020
ion homeostasisGO:00508012300.020
cell adhesionGO:00071553250.020
lipid catabolic processGO:0016042840.020
regulation of protein localizationGO:00328802960.020
regulation of purine nucleotide metabolic processGO:19005422640.020
transmembrane transportGO:00550853990.020
regulation of cell differentiationGO:00455953930.020
cellular macromolecule catabolic processGO:00442653800.020
cytoplasmic transportGO:00164823790.020
peripheral nervous system developmentGO:000742220.019
cofactor metabolic processGO:0051186870.019
enzyme linked receptor protein signaling pathwayGO:00071673030.019
organic anion transportGO:00157111030.019
positive regulation of nucleoside metabolic processGO:00459791860.019
protein maturationGO:00516042330.019
cation transmembrane transportGO:00986552380.019
carboxylic acid catabolic processGO:0046395710.019
negative regulation of cellular amine metabolic processGO:003323930.019
positive regulation of purine nucleotide metabolic processGO:19005442270.019
cellular chemical homeostasisGO:00550821800.019
neuromuscular junction developmentGO:000752830.019
secretion by cellGO:00329402260.019
guanosine containing compound metabolic processGO:19010682440.019
regulation of cell cycleGO:00517263930.019
immune responseGO:00069553070.018
morphogenesis of embryonic epitheliumGO:001633140.018
divalent metal ion transportGO:00708381520.018
positive regulation of apoptotic processGO:00430652460.018
negative regulation of programmed cell deathGO:00430693210.018
cell projection organizationGO:00300302520.018
cellular homeostasisGO:00197251960.018
cation transportGO:00068123310.018
gtp catabolic processGO:00061842370.018
regulation of cell motilityGO:20001452990.018
negative regulation of multicellular organismal processGO:00512413170.018
cellular response to dna damage stimulusGO:00069743790.018
small molecule catabolic processGO:0044282920.018
positive regulation of cell proliferationGO:00082843010.018
regulation of cytoskeleton organizationGO:00514931770.018
regenerationGO:003109940.018
guanosine containing compound catabolic processGO:19010692390.018
ion transmembrane transportGO:00342203380.018
positive regulation of immune system processGO:00026842830.018
protein catabolic processGO:00301633250.018
inorganic ion transmembrane transportGO:00986602310.018
microtubule based processGO:00070172100.018
histone modificationGO:00165702510.018
alcohol metabolic processGO:00060661140.018
positive regulation of nucleotide catabolic processGO:00308131850.017
apoptotic signaling pathwayGO:00971902680.017
inorganic cation transmembrane transportGO:00986621940.017
purine ribonucleoside monophosphate metabolic processGO:00091671860.017
negative regulation of cellular amino acid metabolic processGO:004576320.017
positive regulation of cell deathGO:00109422630.017
positive regulation of developmental processGO:00510943140.017
organic hydroxy compound metabolic processGO:19016151470.017
regulation of transferase activityGO:00513383550.017
cardiac muscle cell contractionGO:008600340.017
sulfur compound metabolic processGO:00067901010.017
nervous system developmentGO:00073992930.017
memoryGO:000761330.017
cytokine productionGO:00018162470.017
reactive oxygen species metabolic processGO:0072593750.017
negative regulation of developmental processGO:00510932470.017
regulation of cytokine productionGO:00018172320.017
cation homeostasisGO:00550801890.017
negative regulation of apoptotic processGO:00430663160.017
response to lipidGO:00339932060.017
membrane organizationGO:00610242920.017
regulation of locomotionGO:00400123290.017
actin filament based processGO:00300292240.017
adult locomotory behaviorGO:000834410.017
nucleoside monophosphate metabolic processGO:00091231910.017
cellular response to organonitrogen compoundGO:00714171240.016
regulation of lipid metabolic processGO:0019216960.016
response to organonitrogen compoundGO:00102431560.016
signal transduction by phosphorylationGO:00230142970.016
protein processingGO:00164852260.016
secretionGO:00469032540.016
regulation of cellular response to stressGO:00801352440.016
regulation of reactive oxygen species metabolic processGO:2000377410.016
negative regulation of phosphorus metabolic processGO:00105632670.016
regulation of secretion by cellGO:19035301770.016
atp metabolic processGO:00460341760.016
compound eye developmentGO:004874910.016
cellular protein catabolic processGO:00442572610.016
regulation of establishment of protein localizationGO:00702012420.016
gtp metabolic processGO:00460392390.016
cellular protein complex assemblyGO:00436231880.016
positive regulation of gtpase activityGO:00435471660.016
positive regulation of phosphorylationGO:00423273940.016
positive regulation of nucleotide metabolic processGO:00459812300.016
spermatid differentiationGO:004851540.016
negative regulation of hydrolase activityGO:00513461820.016
cellular cation homeostasisGO:00300031630.016
negative regulation of organelle organizationGO:00106391260.016
positive regulation of secretion by cellGO:19035321080.016
purine nucleoside monophosphate metabolic processGO:00091261860.016
negative regulation of phosphate metabolic processGO:00459362670.016
phospholipid metabolic processGO:0006644990.016
blastoderm segmentationGO:000735020.015
sequestering of calcium ionGO:0051208170.015
fatty acid biosynthetic processGO:0006633460.015
ribonucleoside monophosphate metabolic processGO:00091611870.015
mitotic cell cycle processGO:19030472860.015
photoreceptor cell differentiationGO:004653020.015
carbohydrate derivative biosynthetic processGO:19011372070.015
metal ion homeostasisGO:00550651690.015
vesicle mediated transportGO:00161923710.015
mitotic cell cycleGO:00002783260.015
positive regulation of cellular component biogenesisGO:00440891580.015
positive regulation of programmed cell deathGO:00430682490.015
regulation of protein processingGO:00706131500.015
hindbrain developmentGO:003090230.015
response to organic cyclic compoundGO:00140702040.015
cellular ion homeostasisGO:00068731680.015
rhythmic behaviorGO:000762220.015
endomembrane system organizationGO:00102561960.015
negative regulation of intracellular signal transductionGO:19025321830.015
neurological system processGO:00508771630.015
positive regulation of cytokine productionGO:00018191670.015
chromatin organizationGO:00063253510.015
positive regulation of purine nucleotide catabolic processGO:00331231850.015
divalent inorganic cation transportGO:00725111580.015
response to axon injuryGO:004867810.015
proteolysis involved in cellular protein catabolic processGO:00516032440.015
mitochondrion organizationGO:00070051560.014
proteasomal protein catabolic processGO:00104981760.014
oocyte developmentGO:004859910.014
dephosphorylationGO:00163112090.014
regulation of protein kinase activityGO:00458592890.014
regulation of cell morphogenesisGO:00226041530.014
response to cytokineGO:00340972320.014
covalent chromatin modificationGO:00165692540.014
sensory perception of painGO:001923340.014
regulation of cell cycle processGO:00105642660.014
regulation of gtp catabolic processGO:00331241800.014
positive regulation of secretionGO:00510471160.014
regulation of secretionGO:00510461940.014
embryonic epithelial tube formationGO:000183840.014
microtubule cytoskeleton organizationGO:00002261760.014
anatomical structure formation involved in morphogenesisGO:00486462840.014
regulation of ras protein signal transductionGO:00465781550.014
organic acid catabolic processGO:0016054710.014
growthGO:00400072020.014
regulation of cell migrationGO:00303342890.014
negative regulation of protein modification processGO:00314002000.014
regulation of mapk cascadeGO:00434082620.014
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.014
regulation of dna metabolic processGO:00510521530.014
positive regulation of ion transportGO:0043270870.014
regulation of neural precursor cell proliferationGO:200017740.013
response to inorganic substanceGO:00100351270.013
regulation of intracellular transportGO:00323861950.013
cellular response to lipidGO:00713961270.013
regulation of protein transportGO:00512232130.013
mapk cascadeGO:00001652880.013
regulation of synaptic plasticityGO:004816730.013
negative regulation of cell cycleGO:00457861930.013
metencephalon developmentGO:002203720.013
cellular response to organic cyclic compoundGO:00714071270.013
cellular response to cytokine stimulusGO:00713451810.013
organelle assemblyGO:00709251760.013
rho protein signal transductionGO:0007266260.013
glycerophospholipid metabolic processGO:0006650840.013
cell growthGO:00160491600.013
regulation of gtpase activityGO:00430871800.013
regulation of protein catabolic processGO:00421761550.013
regulation of response to external stimulusGO:00321012220.013
regulation of kinase activityGO:00435493140.013
associative learningGO:000830610.013
spermatid developmentGO:000728640.013
positive regulation of gtp catabolic processGO:00331261660.013
regulation of peptidase activityGO:00525471800.013
circadian behaviorGO:004851220.013
regulation of protein maturationGO:19033171500.013
negative regulation of protein processingGO:00109551420.013
cell substrate adhesionGO:00315891320.013
cell developmentGO:00484683280.013
response to biotic stimulusGO:00096072760.013
matingGO:000761810.013
chromatin modificationGO:00165682980.013
response to external biotic stimulusGO:00432072610.013
cellular metal ion homeostasisGO:00068751460.012
oocyte differentiationGO:000999420.012
protein oligomerizationGO:00512591730.012
negative regulation of phosphorylationGO:00423261740.012
modification dependent protein catabolic processGO:00199412090.012
anterior posterior axis specificationGO:000994820.012
negative regulation of protein maturationGO:19033181420.012
regulation of meiotic cell cycleGO:005144540.012
intracellular protein transportGO:00068862700.012
regulation of immune responseGO:00507762010.012
regulation of cell adhesionGO:00301551660.012
protein acylationGO:00435431380.012
positive regulation of protein transportGO:00512221350.012
regulation of hormone levelsGO:00108171250.012
ubiquitin dependent protein catabolic processGO:00065112060.012
cardiovascular system developmentGO:00723582620.012
positive regulation of synaptic transmissionGO:005080640.012
regulation of protein complex assemblyGO:00432541470.012
coenzyme metabolic processGO:0006732650.012
reactive oxygen species biosynthetic processGO:190340940.012
tissue migrationGO:00901301190.012
protein localization to organelleGO:00333652800.012
positive regulation of protein phosphorylationGO:00019343130.012
cellular response to hormone stimulusGO:00328701250.012
negative regulation of synaptic transmissionGO:005080520.012
peptidyl lysine modificationGO:00182051440.012
regulation of actin filament based processGO:00329701410.012
modification dependent macromolecule catabolic processGO:00436322120.012
meiotic chromosome segregationGO:004513240.012
positive regulation of locomotionGO:00400171860.012
regulation of small gtpase mediated signal transductionGO:00510561560.012
calcium ion transportGO:00068161470.012
response to fungusGO:000962040.012
neurogenesisGO:00220081690.012
positive regulation of cell migrationGO:00303351720.012
sequestering of metal ionGO:0051238240.012
positive regulation of transferase activityGO:00513472270.012
positive regulation of cellular component movementGO:00512721810.012
neural tube formationGO:000184130.012
regulation of cytoplasmic transportGO:19036491490.012
posttranscriptional regulation of gene expressionGO:00106082130.012
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
cellular calcium ion homeostasisGO:00068741170.012
positive regulation of cell differentiationGO:00455972110.012
innate immune responseGO:00450871780.012
response to other organismGO:00517072610.012
divalent inorganic cation homeostasisGO:00725071360.012
sleepGO:003043120.012
anterior posterior axis specification embryoGO:000859520.012
hematopoietic or lymphoid organ developmentGO:00485341860.012
cell activationGO:00017752130.012
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.011
negative regulation of cell proliferationGO:00082852280.011
tripartite regional subdivisionGO:000735120.011
neural tube patterningGO:002153220.011
regulation of endopeptidase activityGO:00525481700.011
negative regulation of transportGO:00510511760.011
negative regulation of transferase activityGO:00513481240.011
cellular lipid catabolic processGO:0044242650.011
positive regulation of organelle organizationGO:00106381950.011
limbic system developmentGO:002176130.011
nucleus localizationGO:005164710.011
protein homooligomerizationGO:00512601000.011
protein targetingGO:00066051870.011
t cell differentiation in thymusGO:003307740.011
regulation of apoptotic signaling pathwayGO:20012331750.011
neuroblast proliferationGO:000740540.011
negative regulation of proteolysisGO:00458611320.011
protein modification by small protein conjugationGO:00324463420.011
organelle fissionGO:00482851490.011
response to growth factorGO:00708482050.011
immune system developmentGO:00025201950.011
glycerolipid biosynthetic processGO:0045017510.011
positive regulation of kinase activityGO:00336742040.011
glycoprotein metabolic processGO:00091001100.011
neurotransmitter secretionGO:000726940.011
hemopoiesisGO:00300971800.011
response to oxidative stressGO:00069791210.011
response to woundingGO:00096111680.011
cellular response to growth factor stimulusGO:00713631970.011
regulation of mitotic cell cycleGO:00073461890.011
cell cycle phase transitionGO:00447701730.011
negative regulation of catabolic processGO:00098951040.011
tube closureGO:006060630.011
morphogenesis of a polarized epitheliumGO:000173830.011
cellular response to external stimulusGO:00714961110.011
regulation of homeostatic processGO:00328441210.011
positive regulation of reactive oxygen species biosynthetic processGO:190342820.011
cell projection morphogenesisGO:00488581290.011
calcium ion homeostasisGO:00550741220.011
head developmentGO:00603221080.011
purine containing compound biosynthetic processGO:0072522880.011
regulation of mitochondrion organizationGO:0010821540.010
cellular response to oxidative stressGO:0034599850.010
protein localization to membraneGO:00726571600.010
chemotaxisGO:00069351570.010
actin cytoskeleton organizationGO:00300362070.010
nucleoside monophosphate catabolic processGO:00091251590.010
protein autophosphorylationGO:00467771230.010
epithelium developmentGO:00604292270.010
generation of neuronsGO:00486991520.010
alpha amino acid metabolic processGO:1901605720.010
regulation of cell growthGO:00015581350.010
regulation of reactive oxygen species biosynthetic processGO:190342630.010
neural tube closureGO:000184330.010
detection of chemical stimulusGO:0009593550.010
nucleotide biosynthetic processGO:00091651090.010
reactive nitrogen species metabolic processGO:200105730.010
protein ubiquitinationGO:00165673140.010
cardiac muscle contractionGO:0060048340.010
peptidyl lysine acetylationGO:00183941010.010
multicellular organismal response to stressGO:003355510.010
wnt signaling pathwayGO:00160551560.010
regulation of glial cell differentiationGO:004568530.010
plasma membrane organizationGO:00070091150.010
regulation of nervous system developmentGO:0051960880.010
rna processingGO:00063962550.010
regulation of meiosisGO:004002030.010
embryonic placenta developmentGO:000189210.010

LHPP disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.064
inherited metabolic disorderDOID:6552420.051
central nervous system diseaseDOID:3311860.025
nervous system diseaseDOID:8634310.025
sensory system diseaseDOID:00501552030.020
organ system cancerDOID:00506861640.018
disease of cellular proliferationDOID:145661740.018
cancerDOID:1621670.018
neurodegenerative diseaseDOID:12891020.015
musculoskeletal system diseaseDOID:172230.015
eye and adnexa diseaseDOID:14921500.014
eye diseaseDOID:56141490.014
immune system diseaseDOID:29141550.013
connective tissue diseaseDOID:651090.012
retinal diseaseDOID:56791180.012
bone diseaseDOID:0080001880.011
hematopoietic system diseaseDOID:741000.010