Homo sapiens

86 known processes

AURKA

aurora kinase A

(Aliases: AIK,BTAK,STK15,AURORA2,AURA,MGC34538,STK7,STK6,ARK1)

AURKA biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
spindle assembly involved in mitosisGO:0090307120.982
Yeast Worm
meiotic chromosome segregationGO:004513240.972
Yeast
nuclear divisionGO:00002801280.930
Yeast Zebrafish Mouse Worm
organelle fissionGO:00482851490.921
Yeast Zebrafish Mouse Worm
spindle assemblyGO:0051225290.909
Yeast Mouse Worm
cytokinesisGO:0000910960.849
Yeast Worm
protein polymerizationGO:0051258710.826
regulation of microtubule based processGO:0032886740.823
microtubule based processGO:00070172100.808
histone serine phosphorylationGO:003540440.795
Mouse
microtubule nucleationGO:000702060.694
spindle organizationGO:0007051530.688
microtubule cytoskeleton organizationGO:00002261760.666
mitotic spindle midzone assemblyGO:005125640.640
Worm
regulation of spindle organizationGO:0090224100.618
sister chromatid segregationGO:0000819540.549
Yeast
cellular protein complex assemblyGO:00436231880.543
Worm
single organism cellular localizationGO:19025803320.485
Yeast
microtubule anchoringGO:0034453240.469
Yeast
mitotic sister chromatid segregationGO:0000070530.450
maintenance of location in cellGO:0051651620.412
Yeast
regulation of mitotic spindle organizationGO:006023660.412
Yeast
cell developmentGO:00484683280.412
Mouse
protein maturationGO:00516042330.408
protein processingGO:00164852260.402
microtubule polymerizationGO:0046785180.393
cellular macromolecular complex assemblyGO:00346223240.368
Worm
chromosome segregationGO:00070591140.353
Yeast Worm
spindle midzone assemblyGO:005125540.343
Worm
negative regulation of cellular component organizationGO:00511292350.333
positive regulation of proteolysisGO:00458621420.317
Mouse
positive regulation of protein phosphorylationGO:00019343130.311
cellular response to dna damage stimulusGO:00069743790.283
regulation of proteolysisGO:00301622930.276
Mouse
protein localization to chromosomeGO:0034502300.274
organelle assemblyGO:00709251760.259
Yeast Mouse Worm
regenerationGO:003109940.245
microtubule polymerization or depolymerizationGO:0031109370.240
peptidyl serine phosphorylationGO:00181051010.200
Mouse Worm
establishment of organelle localizationGO:0051656590.192
regulation of cell cycleGO:00517263930.188
regulation of transferase activityGO:00513383550.169
dephosphorylationGO:00163112090.164
mitotic spindle elongationGO:000002240.154
Worm
determination of adult lifespanGO:000834020.150
protein depolymerizationGO:0051261300.142
centrosome duplicationGO:0051298280.140
positive regulation of cellular component organizationGO:00511303760.136
oogenesisGO:004847720.136
Mouse
negative regulation of protein metabolic processGO:00512483910.134
posttranscriptional regulation of gene expressionGO:00106082130.133
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.130
mitotic spindle organizationGO:0007052270.126
Yeast Mouse Worm
regulation of intracellular transportGO:00323861950.122
Yeast
positive regulation of transferase activityGO:00513472270.122
negative regulation of microtubule polymerization or depolymerizationGO:0031111170.120
mitotic nuclear divisionGO:00070671190.117
Yeast Zebrafish Mouse Worm
chromatin modificationGO:00165682980.116
Mouse
regulation of protein complex assemblyGO:00432541470.113
Yeast
regulation of endopeptidase activityGO:00525481700.107
centrosome cycleGO:0007098320.105
Mouse
mitotic centrosome separationGO:000710010.100
Mouse
meiosis iGO:000712740.099
Yeast Mouse
nucleus localizationGO:005164710.099
regulation of peptidase activityGO:00525471800.097
establishment or maintenance of cytoskeleton polarityGO:003095230.094
negative regulation of cellular protein metabolic processGO:00322693530.093
organelle localizationGO:0051640840.093
Mouse
maintenance of locationGO:00512351120.093
Yeast
positive regulation of phosphorylationGO:00423273940.092
immune system developmentGO:00025201950.088
cell divisionGO:00513011680.088
Yeast Worm
negative regulation of catalytic activityGO:00430863350.086
response to abiotic stimulusGO:00096283360.085
negative regulation of protein processingGO:00109551420.085
response to organic cyclic compoundGO:00140702040.078
Rat
regulation of protein modification by small protein conjugation or removalGO:19033201070.077
positive regulation of protein kinase activityGO:00458601900.077
single fertilizationGO:0007338110.076
negative regulation of cytoskeleton organizationGO:0051494450.075
cellular response to organic cyclic compoundGO:00714071270.075
meiotic nuclear divisionGO:0007126100.074
Yeast Mouse Worm
regulation of protein kinase activityGO:00458592890.072
positive regulation of cellular component biogenesisGO:00440891580.071
regulation of cell differentiationGO:00455953930.066
Mouse
tissue regenerationGO:004224630.066
negative regulation of phosphorus metabolic processGO:00105632670.064
cellular amino acid metabolic processGO:00065201160.064
response to radiationGO:00093141510.063
regulation of attachment of spindle microtubules to kinetochoreGO:005198890.062
negative regulation of proteolysisGO:00458611320.061
regulation of microtubule cytoskeleton organizationGO:0070507610.061
spindle stabilizationGO:004314640.060
regulation of viral processGO:00507921030.059
establishment or maintenance of microtubule cytoskeleton polarityGO:003095120.059
protein localization to organelleGO:00333652800.058
Yeast Mouse
single organism reproductive processGO:0044702980.056
Mouse Worm
dna recombinationGO:0006310770.055
proteolysis involved in cellular protein catabolic processGO:00516032440.055
Mouse
regulation of cellular response to stressGO:00801352440.054
regulation of cytoplasmic transportGO:19036491490.053
Yeast
regulation of cytoskeleton organizationGO:00514931770.053
protein polyubiquitinationGO:00002091100.052
segmentationGO:003528240.051
regulation of proteasomal protein catabolic processGO:0061136870.050
Mouse
nervous system developmentGO:00073992930.047
Mouse
histone modificationGO:00165702510.047
Mouse
attachment of spindle microtubules to kinetochoreGO:0008608170.047
Yeast
regulation of dephosphorylationGO:0035303960.047
negative regulation of bindingGO:0051100570.047
cell morphogenesisGO:00009022960.046
Mouse
nuclear migrationGO:000709710.046
negative regulation of hydrolase activityGO:00513461820.045
regulation of microtubule polymerization or depolymerizationGO:0031110270.045
embryo developmentGO:00097901230.044
Worm
regulation of mitotic metaphase anaphase transitionGO:0030071260.044
negative regulation of apoptotic processGO:00430663160.043
Mouse
regulation of protein localizationGO:00328802960.042
Yeast
post embryonic developmentGO:000979120.042
regulation of protein polymerizationGO:0032271630.041
mitotic cell cycle processGO:19030472860.041
Yeast Zebrafish Mouse Worm
regulation of intracellular protein transportGO:00331571230.039
Yeast
peptidyl serine modificationGO:00182091060.039
Mouse Worm
establishment of nucleus localizationGO:004002310.038
regulation of cardiac muscle tissue growthGO:005502140.038
fertilizationGO:0009566120.036
negative regulation of endopeptidase activityGO:0010951840.036
modification dependent macromolecule catabolic processGO:00436322120.035
Mouse
regulation of chromosome segregationGO:0051983440.035
negative regulation of cell cycleGO:00457861930.035
Yeast Mouse
histone phosphorylationGO:0016572160.034
Mouse
oocyte maturationGO:000155610.033
Mouse
heart developmentGO:0007507950.033
protein autophosphorylationGO:00467771230.032
Worm
protein ubiquitinationGO:00165673140.032
activation of protein kinase activityGO:0032147900.031
regulation of protein processingGO:00706131500.031
regulation of spindle checkpointGO:0090231120.031
Yeast Mouse
establishment or maintenance of cell polarityGO:0007163310.031
cellular response to iron ionGO:007128110.031
mitotic cell cycleGO:00002783260.031
Yeast Zebrafish Mouse Worm
positive regulation of peptidase activityGO:0010952880.030
chemical homeostasisGO:00488783060.030
regulation of protein catabolic processGO:00421761550.029
Mouse
agingGO:0007568660.029
negative regulation of programmed cell deathGO:00430693210.028
Mouse
regulation of cardiac muscle cell proliferationGO:006004340.028
meiotic cell cycleGO:0051321130.027
Yeast Mouse Worm
negative regulation of phosphatase activityGO:0010923610.027
cardiovascular system developmentGO:00723582620.027
response to decreased oxygen levelsGO:0036293960.026
regulation of cellular protein catabolic processGO:1903362960.025
Mouse
response to oxygen levelsGO:00704821000.025
reproductionGO:0000003630.024
Yeast Mouse Worm
ribosome assemblyGO:004225590.024
protein k48 linked ubiquitinationGO:0070936380.024
negative regulation of cell deathGO:00605483450.024
Mouse
establishment of spindle localizationGO:0051293120.024
brain developmentGO:0007420970.023
secretionGO:00469032540.023
regulation of protein transportGO:00512232130.023
Yeast
mitotic cytokinesisGO:0000281190.023
regulation of kinase activityGO:00435493140.023
establishment of protein localization to organelleGO:00725941720.023
Yeast
cellular response to abiotic stimulusGO:00712141170.022
cellular response to radiationGO:0071478650.022
negative regulation of dephosphorylationGO:0035305630.022
microtubule based movementGO:0007018320.022
chromatin organizationGO:00063253510.021
Mouse
positive regulation of response to dna damage stimulusGO:2001022430.021
positive regulation of programmed cell deathGO:00430682490.020
male meiosisGO:000714010.020
protein modification by small protein conjugationGO:00324463420.020
protein importGO:00170381300.020
Yeast
positive regulation of cellular amino acid metabolic processGO:004576430.020
dna repairGO:00062811980.020
negative regulation of cytoplasmic transportGO:1903650460.020
Yeast
neurogenesisGO:00220081690.020
Mouse
cell projection organizationGO:00300302520.020
Mouse
regulation of establishment of protein localizationGO:00702012420.020
Yeast
negative regulation of peptidase activityGO:0010466910.019
cellular macromolecule catabolic processGO:00442653800.019
Mouse
negative regulation of mitotic metaphase anaphase transitionGO:0045841170.019
anatomical structure formation involved in morphogenesisGO:00486462840.019
myosin filament assemblyGO:003103420.019
signal transduction by phosphorylationGO:00230142970.019
regulation of cellular component biogenesisGO:00440872810.019
Yeast
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.019
positive regulation of endopeptidase activityGO:0010950840.018
regulation of protein maturationGO:19033171500.018
regulation of cell divisionGO:00513021160.017
Yeast Worm
oocyte developmentGO:004859910.017
Mouse
spermatid developmentGO:000728640.017
cellular component disassemblyGO:0022411920.016
meiotic cell cycle processGO:190304680.016
Yeast Mouse
positive regulation of spindle checkpointGO:009023270.016
Yeast
regulation of muscle organ developmentGO:0048634270.016
spermatid differentiationGO:004851540.016
positive regulation of cysteine type endopeptidase activityGO:2001056790.016
blastocyst developmentGO:000182430.016
protein localization to chromosome centromeric regionGO:0071459120.016
cellular homeostasisGO:00197251960.016
establishment of chromosome localizationGO:0051303200.016
negative regulation of protein modification processGO:00314002000.016
regulation of phosphatase activityGO:0010921810.016
negative regulation of protein maturationGO:19033181420.016
metaphase plate congressionGO:0051310180.016
positive regulation of kinase activityGO:00336742040.015
generation of neuronsGO:00486991520.015
Mouse
regulation of protein stabilityGO:0031647870.015
regulation of bindingGO:00510981110.015
microtubule cytoskeleton organization involved in mitosisGO:1902850150.015
Yeast Worm
cellular response to oxygen levelsGO:0071453550.015
negative regulation of phosphate metabolic processGO:00459362670.015
chordate embryonic developmentGO:0043009340.015
regulation of dna metabolic processGO:00510521530.015
regulation of cell motilityGO:20001452990.015
regulation of nervous system developmentGO:0051960880.015
positive regulation of intracellular transportGO:00323881040.015
regulation of cell cycle processGO:00105642660.015
multi organism cellular processGO:00447641560.015
mitotic sister chromatid separationGO:0051306180.014
nucleic acid phosphodiester bond hydrolysisGO:00903051020.014
negative regulation of cellular catabolic processGO:0031330830.014
centrosome separationGO:005129930.014
Mouse
regulation of protein localization to nucleusGO:1900180850.014
Yeast
reactive oxygen species metabolic processGO:0072593750.014
regulation of cellular respirationGO:004345740.014
positive regulation of cytoskeleton organizationGO:0051495830.014
regulation of heart growthGO:006042040.013
regulation of mitotic sister chromatid segregationGO:0033047270.013
negative regulation of protein phosphorylationGO:00019331400.013
defense responseGO:00069523150.013
positive regulation of developmental processGO:00510943140.013
Mouse
response to woundingGO:00096111680.013
regulation of stress activated protein kinase signaling cascadeGO:0070302850.013
microtubule depolymerizationGO:0007019180.013
positive regulation of cell deathGO:00109422630.012
sister chromatid biorientationGO:003113420.012
anatomical structure homeostasisGO:00602491000.012
multicellular organism reproductionGO:0032504420.012
Mouse
spindle assembly checkpointGO:0071173170.012
positive regulation of organelle organizationGO:00106381950.012
development of primary sexual characteristicsGO:0045137350.012
Worm
centrosome organizationGO:0051297580.012
Mouse
positive regulation of chromosome organizationGO:2001252410.012
anterior posterior axis specificationGO:000994820.012
Mouse
regulation of mrna metabolic processGO:1903311530.012
negative regulation of intracellular protein transportGO:0090317420.012
Yeast
response to hypoxiaGO:0001666960.012
response to ionizing radiationGO:0010212650.012
regulation of cell activationGO:00508651250.012
leukocyte activationGO:00453211640.012
intrinsic apoptotic signaling pathwayGO:00971931270.011
positive regulation of protein transportGO:00512221350.011
neuromuscular junction developmentGO:000752830.011
tube morphogenesisGO:0035239950.011
sexual reproductionGO:0019953370.011
Mouse
hindbrain developmentGO:003090230.011
chromosome separationGO:0051304230.011
regulation of cysteine type endopeptidase activityGO:20001161270.011
hemopoiesisGO:00300971800.011
mature ribosome assemblyGO:004225650.011
mrna metabolic processGO:00160711750.011
mitotic chromosome condensationGO:0007076110.011
cell projection morphogenesisGO:00488581290.011
Mouse
wound healingGO:00420601150.011
neuron developmentGO:00486661130.010
Mouse
vesicle mediated transportGO:00161923710.010
protein complex disassemblyGO:0043241520.010
regulation of mitotic cell cycleGO:00073461890.010
Yeast
apoptotic signaling pathwayGO:00971902680.010
positive regulation of apoptotic processGO:00430652460.010
intracellular protein transportGO:00068862700.010
Yeast

AURKA disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.074
cancerDOID:1621670.046
organ system cancerDOID:00506861640.014
thoracic cancerDOID:5093210.010
breast cancerDOID:1612210.010
gastrointestinal system cancerDOID:3119520.008
intestinal cancerDOID:10155290.002
large intestine cancerDOID:5672290.002
colon cancerDOID:219250.002
colorectal cancerDOID:9256290.002
colon carcinomaDOID:1520250.000