Homo sapiens

197 known processes

AURKB

aurora kinase B

(Aliases: AIM-1,AIK2,aurkb-sv2,AIM1,STK12,IPL1,STK5,AurB,aurkb-sv1,ARK2)

AURKB biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
spindle assemblyGO:0051225290.992
regulation of cell cycleGO:00517263930.986
chromatin organizationGO:00063253510.984
Mouse Fly
histone modificationGO:00165702510.979
Mouse Fly
spindle midzone assemblyGO:005125540.970
microtubule cytoskeleton organizationGO:00002261760.961
mitotic cell cycleGO:00002783260.955
spindle assembly involved in mitosisGO:0090307120.951
organelle fissionGO:00482851490.944
covalent chromatin modificationGO:00165692540.942
Mouse Fly
chromatin modificationGO:00165682980.927
Mouse Fly
mitotic nuclear divisionGO:00070671190.913
attachment of spindle microtubules to kinetochoreGO:0008608170.912
cell cycle checkpointGO:00000751170.906
regulation of mitosisGO:0007088630.903
spindle checkpointGO:0031577260.903
sister chromatid segregationGO:0000819540.868
Fly
mitotic cell cycle processGO:19030472860.864
cytokinesisGO:0000910960.846
regulation of mitotic metaphase anaphase transitionGO:0030071260.844
microtubule anchoringGO:0034453240.824
positive regulation of exit from mitosisGO:003153620.804
positive regulation of cell cycle processGO:00900681060.783
negative regulation of organelle organizationGO:00106391260.780
cell divisionGO:00513011680.776
spindle organizationGO:0007051530.775
negative regulation of microtubule polymerization or depolymerizationGO:0031111170.769
microtubule organizing center organizationGO:0031023620.747
Fly
mitotic sister chromatid segregationGO:0000070530.731
Fly
regulation of chromosome segregationGO:0051983440.729
nuclear divisionGO:00002801280.706
mitotic cell cycle phase transitionGO:00447721620.703
male meiosisGO:000714010.702
regulation of microtubule based processGO:0032886740.696
cellular macromolecule catabolic processGO:00442653800.688
microtubule based processGO:00070172100.676
regulation of cell cycle processGO:00105642660.669
centrosome organizationGO:0051297580.661
Fly
protein processingGO:00164852260.641
positive regulation of cell cycleGO:00457871400.625
organophosphate catabolic processGO:00464344300.618
circulatory system developmentGO:00723592620.581
regulation of attachment of spindle microtubules to kinetochoreGO:005198890.566
regulation of mitotic sister chromatid segregationGO:0033047270.514
chromosome segregationGO:00070591140.509
Fly
modification dependent macromolecule catabolic processGO:00436322120.504
mitotic spindle midzone assemblyGO:005125640.491
metaphase anaphase transition of cell cycleGO:0044784210.477
mitotic cytokinesisGO:0000281190.461
Fly
mitotic sister chromatid separationGO:0051306180.454
purine nucleoside monophosphate catabolic processGO:00091281580.449
positive regulation of transferase activityGO:00513472270.433
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.427
negative regulation of cellular component organizationGO:00511292350.409
protein maturationGO:00516042330.392
negative regulation of cell cycle processGO:00109481210.382
regulation of proteasomal protein catabolic processGO:0061136870.381
type b pancreatic cell proliferationGO:004434200.378
positive regulation of cellular component organizationGO:00511303760.378
cytoskeleton dependent cytokinesisGO:0061640220.367
negative regulation of protein processingGO:00109551420.357
negative regulation of protein depolymerizationGO:1901880170.355
ribonucleoside catabolic processGO:00424544060.334
negative regulation of proteolysisGO:00458611320.329
positive regulation of cell divisionGO:0051781590.328
regulation of microtubule cytoskeleton organizationGO:0070507610.319
regulation of cell differentiationGO:00455953930.309
Fly
cell developmentGO:00484683280.301
Fly
organelle assemblyGO:00709251760.300
dna conformation changeGO:00711031130.291
Fly
negative regulation of mitotic cell cycleGO:00459301020.291
purine nucleoside monophosphate metabolic processGO:00091261860.289
metaphase anaphase transition of mitotic cell cycleGO:0007091210.275
negative regulation of mitotic metaphase anaphase transitionGO:0045841170.271
microtubule cytoskeleton organization involved in mitosisGO:1902850150.260
purine ribonucleoside triphosphate metabolic processGO:00092054110.258
protein complex disassemblyGO:0043241520.255
chromosome localizationGO:0050000200.247
regulation of protein processingGO:00706131500.244
negative regulation of mitotic cell cycle phase transitionGO:1901991850.243
meiotic chromosome segregationGO:004513240.241
cell cycle phase transitionGO:00447701730.241
female gamete generationGO:000729220.239
nuclear migrationGO:000709710.227
cellular protein catabolic processGO:00442572610.224
negative regulation of cell cycleGO:00457861930.219
regulation of transferase activityGO:00513383550.218
nucleosome assemblyGO:0006334500.215
negative regulation of cytoskeleton organizationGO:0051494450.211
purine ribonucleotide catabolic processGO:00091544040.207
protein catabolic processGO:00301633250.206
proteolysis involved in cellular protein catabolic processGO:00516032440.204
regulation of hormone levelsGO:00108171250.201
organelle localizationGO:0051640840.199
Fly
regulation of cell divisionGO:00513021160.198
cellular protein complex disassemblyGO:0043624360.196
purine ribonucleoside catabolic processGO:00461303980.195
regulation of metaphase anaphase transition of cell cycleGO:1902099260.193
metaphase plate congressionGO:0051310180.192
positive regulation of protein kinase activityGO:00458601900.185
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.184
cellular macromolecular complex assemblyGO:00346223240.180
negative regulation of protein metabolic processGO:00512483910.178
negative regulation of catalytic activityGO:00430863350.171
modification dependent protein catabolic processGO:00199412090.170
nucleoside phosphate catabolic processGO:19012924120.170
regulation of protein localizationGO:00328802960.169
establishment of chromosome localizationGO:0051303200.168
protein dna complex subunit organizationGO:0071824800.165
regulation of cell growthGO:00015581350.160
purine containing compound catabolic processGO:00725234110.159
ribonucleoside monophosphate catabolic processGO:00091581580.158
ubiquitin dependent protein catabolic processGO:00065112060.157
purine nucleoside triphosphate catabolic processGO:00091463920.155
mitotic spindle organizationGO:0007052270.154
actin filament based processGO:00300292240.153
maintenance of locationGO:00512351120.153
meiotic nuclear divisionGO:0007126100.149
centrosome duplicationGO:0051298280.148
Fly
regulation of mitotic sister chromatid separationGO:0010965270.145
positive regulation of nuclear divisionGO:0051785270.144
negative regulation of cellular protein metabolic processGO:00322693530.143
mitotic spindle elongationGO:000002240.140
protein modification by small protein conjugationGO:00324463420.140
cellular response to oxygen containing compoundGO:19017012760.139
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052350.136
protein depolymerizationGO:0051261300.135
actin cytoskeleton organizationGO:00300362070.134
single organism cellular localizationGO:19025803320.130
Fly
regulation of oocyte maturationGO:190019310.126
protein dna complex assemblyGO:0065004640.126
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.126
nucleoside catabolic processGO:00091644080.123
negative regulation of cell deathGO:00605483450.123
oogenesisGO:004847720.122
chromatin assemblyGO:0031497610.120
proteasomal protein catabolic processGO:00104981760.120
single organism reproductive processGO:0044702980.119
Fly
nucleoside triphosphate catabolic processGO:00091433940.119
positive regulation of mitosisGO:0045840250.118
spindle elongationGO:005123140.114
regulation of cell cycle phase transitionGO:19019871260.114
cellular response to endogenous stimulusGO:00714953360.114
regulation of cellular protein catabolic processGO:1903362960.113
regulation of mitotic cell cycleGO:00073461890.113
regulation of proteolysisGO:00301622930.112
regulation of protein maturationGO:19033171500.111
regulation of bindingGO:00510981110.110
cellular response to dna damage stimulusGO:00069743790.109
regulation of homeostatic processGO:00328441210.108
ribonucleoside triphosphate metabolic processGO:00091994120.106
regulation of secretion by cellGO:19035301770.106
nucleoside monophosphate metabolic processGO:00091231910.105
maintenance of protein location in cellGO:0032507560.103
positive regulation of mitotic cell cycle phase transitionGO:1901992190.101
cellular response to monosaccharide stimulusGO:0071326100.101
nucleotide catabolic processGO:00091664080.101
oocyte differentiationGO:000999420.100
centrosome cycleGO:0007098320.100
Fly
cell type specific apoptotic processGO:00972851250.097
negative regulation of cell cycle phase transitionGO:1901988890.097
regulation of cytoskeleton organizationGO:00514931770.097
reproductive processGO:00224141060.096
Fly
regulation of hormone secretionGO:0046883570.095
positive regulation of protein phosphorylationGO:00019343130.095
negative regulation of hydrolase activityGO:00513461820.090
mitotic spindle checkpointGO:0071174180.089
regulation of protein kinase activityGO:00458592890.088
purine nucleoside triphosphate metabolic processGO:00091444120.088
regulation of nuclear divisionGO:0051783650.088
purine ribonucleoside triphosphate catabolic processGO:00092073910.088
sister chromatid cohesionGO:0007062240.086
regulation of protein transportGO:00512232130.085
regulation of cytokinesisGO:0032465450.085
regulation of protein catabolic processGO:00421761550.084
positive regulation of cellular protein catabolic processGO:1903364370.084
positive regulation of organelle organizationGO:00106381950.080
ribonucleotide catabolic processGO:00092614050.080
negative regulation of cellular catabolic processGO:0031330830.079
heart developmentGO:0007507950.079
negative regulation of endopeptidase activityGO:0010951840.078
regulation of secretionGO:00510461940.078
regulation of protein depolymerizationGO:1901879220.077
regulation of microtubule polymerization or depolymerizationGO:0031110270.077
regulation of peptidase activityGO:00525471800.075
cellular protein complex assemblyGO:00436231880.074
histone serine phosphorylationGO:003540440.074
Mouse
response to hormoneGO:00097251750.071
dna damage checkpointGO:0000077680.071
cell projection organizationGO:00300302520.069
dna replication independent nucleosome organizationGO:0034724270.068
ribonucleoside monophosphate metabolic processGO:00091611870.068
intrinsic apoptotic signaling pathwayGO:00971931270.067
atp metabolic processGO:00460341760.067
dna integrity checkpointGO:0031570710.066
cellular response to decreased oxygen levelsGO:0036294510.066
positive regulation of phosphorylationGO:00423273940.064
atp catabolic processGO:00062001570.062
regulation of cytoplasmic transportGO:19036491490.062
exit from mitosisGO:0010458100.062
positive regulation of cytokinesisGO:0032467290.062
purine nucleoside catabolic processGO:00061523980.062
meiosis iGO:000712740.062
response to oxygen containing compoundGO:19017003690.061
chromosome separationGO:0051304230.059
negative regulation of mitosisGO:0045839240.059
dna packagingGO:0006323770.059
Fly
regulation of protein targetingGO:1903533910.057
purine nucleotide catabolic processGO:00061954050.057
regulation of peptide hormone secretionGO:0090276410.057
neuron differentiationGO:00301821380.057
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.056
establishment of organelle localizationGO:0051656590.056
Fly
cellular homeostasisGO:00197251960.056
neuron projection developmentGO:00311751060.055
protein ubiquitinationGO:00165673140.055
negative regulation of apoptotic processGO:00430663160.054
regulation of intracellular transportGO:00323861950.053
developmental process involved in reproductionGO:0003006660.053
Fly
mitotic cell cycle checkpointGO:0007093680.053
regulation of type b pancreatic cell proliferationGO:006146910.052
maintenance of protein locationGO:0045185570.052
positive regulation of cell differentiationGO:00455972110.052
negative regulation of phosphate metabolic processGO:00459362670.052
hormone transportGO:0009914680.051
histone phosphorylationGO:0016572160.051
Mouse Fly
cell morphogenesisGO:00009022960.050
regulation of endopeptidase activityGO:00525481700.050
positive regulation of mitotic cell cycleGO:0045931600.049
post embryonic developmentGO:000979120.049
protein localization to chromosomeGO:0034502300.049
peptidyl threonine modificationGO:0018210450.048
purine ribonucleoside metabolic processGO:00461284370.048
actomyosin structure organizationGO:0031032590.047
positive regulation of proteolysisGO:00458621420.046
regenerationGO:003109940.045
maintenance of location in cellGO:0051651620.044
nucleoside triphosphate metabolic processGO:00091414220.044
regulation of protein dephosphorylationGO:0035304180.044
negative regulation of chromosome organizationGO:2001251480.043
regulation of mitotic cell cycle phase transitionGO:19019901180.043
negative regulation of programmed cell deathGO:00430693210.043
cellular component morphogenesisGO:00329893140.043
response to abiotic stimulusGO:00096283360.042
golgi inheritanceGO:004831320.042
cellular component disassemblyGO:0022411920.042
multicellular organismal agingGO:001025930.042
regulation of intracellular protein transportGO:00331571230.042
actomyosin contractile ring organizationGO:004483710.040
spindle assembly checkpointGO:0071173170.039
meiotic cell cycle processGO:190304680.039
regulation of apoptotic signaling pathwayGO:20012331750.039
positive regulation of dna metabolic processGO:0051054730.039
regulation of sister chromatid segregationGO:0033045270.037
hormone secretionGO:0046879650.037
regulation of establishment of protein localizationGO:00702012420.037
negative regulation of cell divisionGO:0051782310.037
positive regulation of catabolic processGO:00098963100.037
centrosome separationGO:005129930.037
Fly
activation of protein kinase activityGO:0032147900.035
negative regulation of phosphorus metabolic processGO:00105632670.035
dna replication independent nucleosome assemblyGO:0006336270.035
negative regulation of protein maturationGO:19033181420.035
embryo developmentGO:00097901230.035
regulation of dephosphorylationGO:0035303960.035
microtubule polymerization or depolymerizationGO:0031109370.034
reproductionGO:0000003630.034
Fly
mitotic spindle assembly checkpointGO:0007094140.034
insulin secretionGO:0030073390.034
protein autophosphorylationGO:00467771230.034
nuclear transportGO:00511691790.034
negative regulation of sister chromatid segregationGO:0033046170.033
negative regulation of mitotic sister chromatid separationGO:2000816170.033
regulation of nucleocytoplasmic transportGO:0046822980.033
glycosyl compound catabolic processGO:19016584130.033
amide transportGO:0042886760.033
positive regulation of developmental processGO:00510943140.033
cyclin catabolic processGO:000805460.032
dna duplex unwindingGO:0032508300.032
positive regulation of protein transportGO:00512221350.031
mitotic metaphase plate congressionGO:0007080140.031
negative regulation of cell growthGO:0030308830.031
positive regulation of cellular amino acid metabolic processGO:004576430.031
sister chromatid biorientationGO:003113420.031
apoptotic signaling pathwayGO:00971902680.030
regulation of chromosome organizationGO:00330441030.030
oocyte maturationGO:000155610.030
immune responseGO:00069553070.030
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043154460.030
response to oxygen levelsGO:00704821000.029
secretionGO:00469032540.029
purine ribonucleoside monophosphate catabolic processGO:00091691580.029
protein polymerizationGO:0051258710.029
cell part morphogenesisGO:00329901370.029
protein oligomerizationGO:00512591730.029
regulation of protein localization to nucleusGO:1900180850.029
g1 s transition of mitotic cell cycleGO:0000082780.029
establishment of nucleus localizationGO:004002310.028
response to thyroid hormoneGO:009706690.028
protein localization to nucleusGO:00345041360.028
nucleoside monophosphate catabolic processGO:00091251590.028
negative regulation of erythrocyte differentiationGO:004564730.028
cell cycle g1 s phase transitionGO:0044843800.028
determination of adult lifespanGO:000834020.028
regulation of neuron apoptotic processGO:0043523350.027
macromolecular complex disassemblyGO:0032984600.027
cardiovascular system developmentGO:00723582620.027
negative regulation of neuron apoptotic processGO:0043524230.027
vesicle mediated transportGO:00161923710.027
glucose homeostasisGO:0042593310.027
negative regulation of multicellular organismal processGO:00512413170.026
negative regulation of catabolic processGO:00098951040.026
positive regulation of cellular catabolic processGO:00313312840.026
positive regulation of hydrolase activityGO:00513453310.026
growthGO:00400072020.026
regulation of kinase activityGO:00435493140.025
cell growthGO:00160491600.025
dna repairGO:00062811980.025
neurogenesisGO:00220081690.025
Fly
cell morphogenesis involved in differentiationGO:00009041440.025
negative regulation of cellular protein catabolic processGO:1903363380.025
positive regulation of chromosome organizationGO:2001252410.024
negative regulation of myeloid cell differentiationGO:0045638420.024
tube developmentGO:00352951250.024
cellular response to hypoxiaGO:0071456510.024
protein targetingGO:00066051870.023
chemical homeostasisGO:00488783060.023
negative regulation of developmental processGO:00510932470.022
cellular amino acid metabolic processGO:00065201160.022
negative regulation of peptidase activityGO:0010466910.022
actomyosin contractile ring assemblyGO:000091510.022
negative regulation of metaphase anaphase transition of cell cycleGO:1902100170.022
negative regulation of growthGO:0045926970.021
nucleus localizationGO:005164710.021
regulation of gene silencingGO:0060968240.021
nucleocytoplasmic transportGO:00069131760.021
intracellular protein transportGO:00068862700.021
neuron projection morphogenesisGO:0048812500.020
digestive tract developmentGO:0048565750.020
positive regulation of chromosome segregationGO:005198490.020
positive regulation of proteasomal protein catabolic processGO:1901800350.020
regulation of protein complex assemblyGO:00432541470.020
negative regulation of protein transportGO:0051224750.019
negative regulation of protein catabolic processGO:0042177590.019
glomerular epithelial cell developmentGO:007231030.019
posttranscriptional regulation of gene expressionGO:00106082130.019
negative regulation of nucleocytoplasmic transportGO:0046823370.019
regulation of growthGO:00400081650.019
dephosphorylationGO:00163112090.019
positive regulation of intracellular transportGO:00323881040.019
negative regulation of mitotic sister chromatid segregationGO:0033048170.019
generation of neuronsGO:00486991520.019
Fly
cell fate determinationGO:000170930.019
Fly
erythrocyte homeostasisGO:0034101310.019
neuron developmentGO:00486661130.019
vasculature developmentGO:00019441810.018
dna replicationGO:00062601160.018
cellular response to oxygen levelsGO:0071453550.018
positive regulation of programmed cell deathGO:00430682490.018
regulation of cellular amine metabolic processGO:0033238110.018
regulation of cellular amino acid metabolic processGO:000652160.018
regulation of exit from mitosisGO:000709660.018
single fertilizationGO:0007338110.017
ribonucleoside triphosphate catabolic processGO:00092033910.017
positive regulation of transportGO:00510503360.017
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.017
single organism membrane organizationGO:00448022680.017
regulation of cellular ketone metabolic processGO:0010565500.017
gonad developmentGO:0008406340.016
regulation of phosphatase activityGO:0010921810.016
regulation of spindle organizationGO:0090224100.016
response to decreased oxygen levelsGO:0036293960.016
positive regulation of kinase activityGO:00336742040.016
negative regulation of neuron deathGO:1901215320.016
neuron apoptotic processGO:0051402390.016
hemopoiesisGO:00300971800.016
positive regulation of multi organism processGO:0043902560.016
immune system developmentGO:00025201950.016
response to hypoxiaGO:0001666960.016
positive regulation of apoptotic signaling pathwayGO:2001235700.015
endocytosisGO:00068971590.015
erythrocyte differentiationGO:0030218280.015
mitotic dna damage checkpointGO:0044773280.015
protein k11 linked ubiquitinationGO:0070979240.015
regulation of protein import into nucleusGO:0042306780.015
purine ribonucleoside monophosphate metabolic processGO:00091671860.015
cytoplasmic transportGO:00164823790.015
positive regulation of mitotic sister chromatid separationGO:190197060.015
cytokinetic processGO:0032506120.015
peptidyl serine modificationGO:00182091060.015
Mouse
negative regulation of phosphorylationGO:00423261740.015
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145250.015
microtubule based movementGO:0007018320.015
regulation of peptide transportGO:0090087620.014
cellular ketone metabolic processGO:0042180800.014
somatic muscle developmentGO:000752510.014
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436300.014
regulation of erythrocyte differentiationGO:0045646170.014
peptide transportGO:0015833740.014
anatomical structure formation involved in morphogenesisGO:00486462840.014
Fly
protein dephosphorylationGO:0006470810.014
positive regulation of apoptotic processGO:00430652460.014
negative regulation of proteasomal protein catabolic processGO:1901799320.014
cellular response to hormone stimulusGO:00328701250.014
meiotic cell cycleGO:0051321130.013
negative regulation of cell differentiationGO:00455961710.013
positive regulation of growthGO:0045927580.013
negative regulation of transportGO:00510511760.013
negative regulation of immune system processGO:00026831360.013
tube morphogenesisGO:0035239950.013
protein complex localizationGO:0031503310.013
enzyme linked receptor protein signaling pathwayGO:00071673030.013
regulation of peptide secretionGO:0002791420.013
myosin filament assemblyGO:003103420.012
regulation of protein stabilityGO:0031647870.012
neuromuscular junction developmentGO:000752830.012
regulation of gene expression epigeneticGO:0040029730.012
sexual reproductionGO:0019953370.012
Fly
signal transduction in response to dna damageGO:0042770570.012
peptide secretionGO:0002790510.012
developmental growthGO:0048589480.012
regulation of protein bindingGO:0043393660.012
tissue regenerationGO:004224630.011
cell projection morphogenesisGO:00488581290.011
response to uvGO:0009411730.011
regulation of myeloid cell differentiationGO:0045637810.011
cell cell signalingGO:00072671550.011
cellular amine metabolic processGO:0044106410.011
negative regulation of cell sizeGO:004579230.011
response to metal ionGO:0010038840.011
regulation of neuron deathGO:1901214560.011
nucleosome organizationGO:0034728660.011
nervous system developmentGO:00073992930.011
Fly
peptidyl serine phosphorylationGO:00181051010.011
Mouse
protein localization to organelleGO:00333652800.011
viral processGO:00160321460.011
negative regulation of protein import into nucleusGO:0042308300.011
regulation of protein modification by small protein conjugation or removalGO:19033201070.011
digestive system developmentGO:0055123750.011
response to radiationGO:00093141510.010
receptor mediated endocytosisGO:0006898840.010
amine metabolic processGO:0009308440.010
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435300.010
gtp metabolic processGO:00460392390.010
membrane organizationGO:00610242920.010
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051350.010
regulation of cell cycle checkpointGO:1901976210.010

AURKB disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.122
gastrointestinal system cancerDOID:3119520.036
organ system cancerDOID:00506861640.036
cancerDOID:1621670.036
musculoskeletal system diseaseDOID:172230.025