Homo sapiens

0 known processes

PRUNE2

prune homolog 2 (Drosophila)

(Aliases: bA214N16.3,FLJ59118,FLJ50060,KIAA0367,A214N16.3,RP11-58J3.2,C9orf65,BNIPXL,FLJ54876,BMCC1,DKFZp762K117)

PRUNE2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.062
amine metabolic processGO:0009308440.060
Human
cellular amine metabolic processGO:0044106410.054
Human
locomotory behaviorGO:000762610.051
cellular ketone metabolic processGO:0042180800.051
Human
regulation of cellular amine metabolic processGO:0033238110.049
Human
regulation of cellular amino acid metabolic processGO:000652160.048
Human
cellular amino acid metabolic processGO:00065201160.044
Human
dna conformation changeGO:00711031130.044
regulation of cellular ketone metabolic processGO:0010565500.041
Human
nucleoside phosphate catabolic processGO:19012924120.041
Human
purine ribonucleoside metabolic processGO:00461284370.040
Human
organophosphate catabolic processGO:00464344300.040
Human
multicellular organismal agingGO:001025930.040
determination of adult lifespanGO:000834020.040
positive regulation of cellular amine metabolic processGO:003324070.040
nucleoside triphosphate metabolic processGO:00091414220.039
Human
nucleoside catabolic processGO:00091644080.038
Human
purine ribonucleoside triphosphate metabolic processGO:00092054110.037
Human
chromatin organizationGO:00063253510.036
cellular protein catabolic processGO:00442572610.035
purine ribonucleotide catabolic processGO:00091544040.035
Human
nucleoside triphosphate catabolic processGO:00091433940.035
Human
purine ribonucleoside catabolic processGO:00461303980.034
Human
purine containing compound catabolic processGO:00725234110.034
Human
ribonucleoside catabolic processGO:00424544060.034
Human
glycosyl compound catabolic processGO:19016584130.034
Human
purine nucleoside catabolic processGO:00061523980.034
Human
ion transmembrane transportGO:00342203380.034
negative regulation of protein metabolic processGO:00512483910.033
positive regulation of hydrolase activityGO:00513453310.033
Human
system processGO:00030083490.033
purine nucleoside triphosphate catabolic processGO:00091463920.033
Human
ribonucleotide catabolic processGO:00092614050.032
Human
cell developmentGO:00484683280.032
single organism cellular localizationGO:19025803320.032
protein modification by small protein conjugationGO:00324463420.031
positive regulation of cellular amino acid metabolic processGO:004576430.031
nucleotide catabolic processGO:00091664080.031
Human
purine nucleoside triphosphate metabolic processGO:00091444120.031
Human
purine ribonucleoside triphosphate catabolic processGO:00092073910.031
Human
ribonucleoside triphosphate catabolic processGO:00092033910.031
Human
negative regulation of multicellular organismal processGO:00512413170.030
cytoplasmic transportGO:00164823790.030
purine nucleotide catabolic processGO:00061954050.030
Human
regulation of locomotionGO:00400123290.030
cation transportGO:00068123310.030
protein processingGO:00164852260.030
response to oxygen containing compoundGO:19017003690.030
regulation of cell differentiationGO:00455953930.030
embryonic epithelial tube formationGO:000183840.029
transmembrane transportGO:00550853990.029
lipid metabolic processGO:00066293810.029
biological adhesionGO:00226103310.028
female gamete generationGO:000729220.028
segmentationGO:003528240.028
regulation of proteolysisGO:00301622930.028
memoryGO:000761330.027
negative regulation of catalytic activityGO:00430863350.027
positive regulation of catabolic processGO:00098963100.027
Human
anatomical structure formation involved in morphogenesisGO:00486462840.027
cell adhesionGO:00071553250.027
inorganic cation transmembrane transportGO:00986621940.027
ribonucleoside triphosphate metabolic processGO:00091994120.027
Human
small gtpase mediated signal transductionGO:0007264780.027
Human
cardiovascular system developmentGO:00723582620.026
regulation of protein localizationGO:00328802960.026
Human
secretionGO:00469032540.026
positive regulation of phosphorylationGO:00423273940.026
neurotransmitter secretionGO:000726940.026
metal ion transportGO:00300012720.026
positive regulation of cellular catabolic processGO:00313312840.026
Human
cellular macromolecular complex assemblyGO:00346223240.025
positive regulation of cellular component organizationGO:00511303760.025
adult locomotory behaviorGO:000834410.025
positive regulation of nucleotide metabolic processGO:00459812300.025
Human
nervous system developmentGO:00073992930.025
response to abiotic stimulusGO:00096283360.025
ras protein signal transductionGO:0007265730.025
maintenance of locationGO:00512351120.025
negative regulation of developmental processGO:00510932470.025
regulation of purine nucleotide metabolic processGO:19005422640.024
Human
actin filament based processGO:00300292240.024
regulation of nucleotide metabolic processGO:00061402690.024
Human
gtp catabolic processGO:00061842370.024
Human
protein ubiquitinationGO:00165673140.024
guanosine containing compound metabolic processGO:19010682440.024
Human
cellular lipid metabolic processGO:00442553030.024
negative regulation of cellular protein metabolic processGO:00322693530.024
inorganic ion transmembrane transportGO:00986602310.023
proteolysis involved in cellular protein catabolic processGO:00516032440.023
cellular macromolecule catabolic processGO:00442653800.023
cell morphogenesisGO:00009022960.023
spinal cord developmentGO:002151040.022
neurological system processGO:00508771630.022
neuromuscular junction developmentGO:000752830.022
regulation of nucleotide catabolic processGO:00308112050.022
Human
regulation of cell motilityGO:20001452990.022
positive regulation of purine nucleotide metabolic processGO:19005442270.022
Human
chemical homeostasisGO:00488783060.022
cation transmembrane transportGO:00986552380.022
negative regulation of cellular component organizationGO:00511292350.022
vesicle mediated transportGO:00161923710.022
regulation of protein processingGO:00706131500.022
circulatory system developmentGO:00723592620.022
regulation of nucleoside metabolic processGO:00091182090.022
Human
circadian behaviorGO:004851220.022
regulation of purine nucleotide catabolic processGO:00331212050.022
Human
regenerationGO:003109940.022
dephosphorylationGO:00163112090.022
cell projection organizationGO:00300302520.021
regulation of cellular component movementGO:00512703340.021
protein catabolic processGO:00301633250.021
defense responseGO:00069523150.021
cation homeostasisGO:00550801890.021
mitotic cell cycleGO:00002783260.021
ubiquitin dependent protein catabolic processGO:00065112060.021
membrane organizationGO:00610242920.020
negative regulation of protein maturationGO:19033181420.020
cellular component morphogenesisGO:00329893140.020
rhythmic behaviorGO:000762220.020
regulation of cellular component biogenesisGO:00440872810.020
signal transduction by phosphorylationGO:00230142970.020
secretion by cellGO:00329402260.020
muscle system processGO:0003012810.020
mitotic cell cycle processGO:19030472860.020
regulation of gtp catabolic processGO:00331241800.020
Human
regulation of transferase activityGO:00513383550.020
negative regulation of protein processingGO:00109551420.020
regulation of establishment of protein localizationGO:00702012420.020
spermatid differentiationGO:004851540.020
regulation of kinase activityGO:00435493140.020
immune responseGO:00069553070.020
organelle assemblyGO:00709251760.020
ion homeostasisGO:00508012300.019
regulation of intracellular transportGO:00323861950.019
intracellular protein transportGO:00068862700.019
modification dependent macromolecule catabolic processGO:00436322120.019
regulation of ion transportGO:00432691890.019
guanosine containing compound catabolic processGO:19010692390.019
Human
positive regulation of nucleoside metabolic processGO:00459791860.019
Human
cellular homeostasisGO:00197251960.019
positive regulation of nucleotide catabolic processGO:00308131850.019
Human
regulation of neurotransmitter secretionGO:004692830.019
negative regulation of cellular amine metabolic processGO:003323930.019
Human
cellular protein complex assemblyGO:00436231880.019
single organism membrane organizationGO:00448022680.019
cellular response to dna damage stimulusGO:00069743790.019
positive regulation of protein phosphorylationGO:00019343130.019
oogenesisGO:004847720.018
negative regulation of cellular amino acid metabolic processGO:004576320.018
Human
innate immune responseGO:00450871780.018
gtp metabolic processGO:00460392390.018
Human
spermatid developmentGO:000728640.018
blastoderm segmentationGO:000735020.018
negative regulation of phosphorus metabolic processGO:00105632670.018
organonitrogen compound biosynthetic processGO:19015662000.018
negative regulation of cell deathGO:00605483450.018
neurogenesisGO:00220081690.018
negative regulation of proteolysisGO:00458611320.018
regulation of anatomical structure morphogenesisGO:00226032860.018
actin filament based movementGO:0030048170.018
carbohydrate derivative biosynthetic processGO:19011372070.018
negative regulation of phosphate metabolic processGO:00459362670.018
positive regulation of synaptic transmissionGO:005080640.018
positive regulation of immune system processGO:00026842830.018
cellular ion homeostasisGO:00068731680.018
morphogenesis of embryonic epitheliumGO:001633140.018
regulation of synaptic plasticityGO:004816730.017
peripheral nervous system developmentGO:000742220.017
negative regulation of hydrolase activityGO:00513461820.017
negative regulation of protein modification processGO:00314002000.017
regulation of protein kinase activityGO:00458592890.017
negative regulation of programmed cell deathGO:00430693210.017
cardiac muscle cell contractionGO:008600340.017
regulation of secretionGO:00510461940.017
regulation of cell cycleGO:00517263930.017
compound eye developmentGO:004874910.017
dosage compensationGO:000754930.017
actin cytoskeleton organizationGO:00300362070.017
response to biotic stimulusGO:00096072760.017
negative regulation of cell proliferationGO:00082852280.017
Human
regulation of mapk cascadeGO:00434082620.017
muscle contractionGO:0006936730.017
epithelium developmentGO:00604292270.017
positive regulation of transportGO:00510503360.017
monocarboxylic acid metabolic processGO:00327871850.017
carbohydrate metabolic processGO:00059752070.017
positive regulation of purine nucleotide catabolic processGO:00331231850.017
Human
protein localization to organelleGO:00333652800.017
negative regulation of apoptotic processGO:00430663160.017
matingGO:000761810.016
neural tube closureGO:000184330.016
response to other organismGO:00517072610.016
oocyte differentiationGO:000999420.016
oocyte developmentGO:004859910.016
associative learningGO:000830610.016
anterior posterior axis specificationGO:000994820.016
cellular cation homeostasisGO:00300031630.016
microtubule cytoskeleton organizationGO:00002261760.016
regulation of cellular response to stressGO:00801352440.016
regulation of cell migrationGO:00303342890.016
negative regulation of intracellular signal transductionGO:19025321830.016
cellular response to oxygen containing compoundGO:19017012760.016
purine ribonucleoside monophosphate metabolic processGO:00091671860.016
small molecule biosynthetic processGO:00442831570.016
regulation of secretion by cellGO:19035301770.016
tube closureGO:006060630.016
spinal cord dorsal ventral patterningGO:002151320.016
hindbrain developmentGO:003090230.015
regulation of protein catabolic processGO:00421761550.015
positive regulation of cell deathGO:00109422630.015
protein maturationGO:00516042330.015
rho protein signal transductionGO:0007266260.015
posttranscriptional regulation of gene expressionGO:00106082130.015
mapk cascadeGO:00001652880.015
ribonucleoside monophosphate metabolic processGO:00091611870.015
cellular chemical homeostasisGO:00550821800.015
atp metabolic processGO:00460341760.015
regulation of cytoplasmic transportGO:19036491490.015
purine nucleoside monophosphate metabolic processGO:00091261860.015
modification dependent protein catabolic processGO:00199412090.015
photoreceptor cell differentiationGO:004653020.015
regulation of protein maturationGO:19033171500.015
metal ion homeostasisGO:00550651690.015
sequestering of metal ionGO:0051238240.015
reactive oxygen species biosynthetic processGO:190340940.015
negative regulation of transportGO:00510511760.015
regulation of ion transmembrane transportGO:00347651320.015
regulation of response to external stimulusGO:00321012220.015
monovalent inorganic cation transportGO:00156721280.015
nucleoside monophosphate metabolic processGO:00091231910.015
endomembrane system organizationGO:00102561960.015
glycoprotein metabolic processGO:00091001100.015
apoptotic signaling pathwayGO:00971902680.015
negative regulation of cell cycleGO:00457861930.015
regulation of cell cycle processGO:00105642660.014
sensory perceptionGO:00076001030.014
organic hydroxy compound metabolic processGO:19016151470.014
positive regulation of gtp catabolic processGO:00331261660.014
Human
neuroblast proliferationGO:000740540.014
regulation of epithelial cell migrationGO:0010632930.014
proteasomal protein catabolic processGO:00104981760.014
cell fate determinationGO:000170930.014
sequestering of calcium ionGO:0051208170.014
regulation of membrane potentialGO:0042391950.014
generation of neuronsGO:00486991520.014
microtubule based processGO:00070172100.014
positive regulation of gtpase activityGO:00435471660.014
Human
actin mediated cell contractionGO:0070252120.014
ameboidal type cell migrationGO:00016671350.014
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.014
organophosphate biosynthetic processGO:00904071630.014
lipid biosynthetic processGO:00086101770.014
regulation of gtpase activityGO:00430871800.014
Human
oxidation reduction processGO:00551143960.014
regulation of gene expression epigeneticGO:0040029730.014
positive regulation of transferase activityGO:00513472270.014
positive regulation of programmed cell deathGO:00430682490.014
cellular response to cytokine stimulusGO:00713451810.014
cellular metal ion homeostasisGO:00068751460.014
response to organic cyclic compoundGO:00140702040.014
stem cell divisionGO:001714520.014
positive regulation of kinase activityGO:00336742040.014
reactive oxygen species metabolic processGO:0072593750.014
response to growth factorGO:00708482050.014
histone modificationGO:00165702510.014
enzyme linked receptor protein signaling pathwayGO:00071673030.014
response to axon injuryGO:004867810.013
motor neuron axon guidanceGO:000804520.013
positive regulation of apoptotic processGO:00430652460.013
regulation of ras protein signal transductionGO:00465781550.013
Human
cell activationGO:00017752130.013
single organism carbohydrate metabolic processGO:00447231930.013
tripartite regional subdivisionGO:000735120.013
regulation of meiotic cell cycleGO:005144540.013
ventral spinal cord developmentGO:002151710.013
cell cycle phase transitionGO:00447701730.013
covalent chromatin modificationGO:00165692540.013
positive regulation of cellular component movementGO:00512721810.013
purine nucleoside monophosphate catabolic processGO:00091281580.013
reactive nitrogen species metabolic processGO:200105730.013
cell growthGO:00160491600.013
regulation of reactive oxygen species biosynthetic processGO:190342630.013
syncytium formation by plasma membrane fusionGO:000076820.013
rna processingGO:00063962550.013
response to virusGO:00096151260.013
regulation of cytokine productionGO:00018172320.013
regulation of endopeptidase activityGO:00525481700.013
response to cytokineGO:00340972320.013
cytokine productionGO:00018162470.013
anterior posterior axis specification embryoGO:000859520.013
cell part morphogenesisGO:00329901370.013
protein localization to membraneGO:00726571600.013
divalent inorganic cation homeostasisGO:00725071360.013
central nervous system developmentGO:00074171230.013
cell divisionGO:00513011680.013
neuron differentiationGO:00301821380.013
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.013
growthGO:00400072020.013
Human
nucleocytoplasmic transportGO:00069131760.013
calcium ion transportGO:00068161470.013
negative regulation of smoothened signaling pathwayGO:004587930.013
cell fate commitment involved in pattern specificationGO:006058110.012
regulation of cell morphogenesisGO:00226041530.012
response to external biotic stimulusGO:00432072610.012
chromatin modificationGO:00165682980.012
angiogenesisGO:00015251470.012
peptidyl tyrosine modificationGO:00182121700.012
establishment of protein localization to organelleGO:00725941720.012
epithelium migrationGO:00901321190.012
response to nitrogen compoundGO:19016981840.012
negative regulation of organelle organizationGO:00106391260.012
nucleoside monophosphate catabolic processGO:00091251590.012
cell projection assemblyGO:00300311260.012
sex determinationGO:000753030.012
atp catabolic processGO:00062001570.012
nitrogen compound transportGO:00717051910.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
regulation of protein ubiquitinationGO:0031396950.012
regulation of ras gtpase activityGO:00323181280.012
Human
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.012
protein targetingGO:00066051870.012
alcohol metabolic processGO:00060661140.012
regulation of peptidase activityGO:00525471800.012
somatic muscle developmentGO:000752510.012
glycerolipid metabolic processGO:00464861070.012
positive regulation of immune responseGO:00507781590.012
regulation of apoptotic signaling pathwayGO:20012331750.012
positive regulation of organelle organizationGO:00106381950.012
specification of organ identityGO:001009230.012
anion transportGO:00068201610.012
rna interferenceGO:001624640.012
regulation of multi organism processGO:00439001570.012
divalent inorganic cation transportGO:00725111580.012
regulation of actin filament based processGO:00329701410.012
response to inorganic substanceGO:00100351270.012
positive regulation of protein kinase activityGO:00458601900.012
single organism cell adhesionGO:00986021790.012
regulation of neural precursor cell proliferationGO:200017740.012
regulation of transmembrane transportGO:00347621390.012
mitochondrion organizationGO:00070051560.012
ribonucleoside monophosphate catabolic processGO:00091581580.012
cellular response to organonitrogen compoundGO:00714171240.012
tissue migrationGO:00901301190.012
multicellular organismal response to stressGO:003355510.012
cellular response to endogenous stimulusGO:00714953360.012
neural tube patterningGO:002153220.012
response to organonitrogen compoundGO:00102431560.012
striated muscle contractionGO:0006941520.012
response to fungusGO:000962040.011
regulation of dephosphorylationGO:0035303960.011
vasodilationGO:004231140.011
regulation of cytoskeleton organizationGO:00514931770.011
response to hormoneGO:00097251750.011
long term memoryGO:000761620.011
negative regulation of phosphorylationGO:00423261740.011
regulation of vesicle mediated transportGO:00606271300.011
limbic system developmentGO:002176130.011
blood vessel morphogenesisGO:00485141620.011
sulfur compound metabolic processGO:00067901010.011
tissue regenerationGO:004224630.011
vasculature developmentGO:00019441810.011
regulation of small gtpase mediated signal transductionGO:00510561560.011
Human
positive regulation of cell migrationGO:00303351720.011
protein homooligomerizationGO:00512601000.011
regulation of cellular protein catabolic processGO:1903362960.011
blood circulationGO:00080151130.011
epithelial cell migrationGO:00106311190.011
purine ribonucleoside monophosphate catabolic processGO:00091691580.011
regulation of immune responseGO:00507762010.011
visual behaviorGO:000763220.011
cellular response to growth factor stimulusGO:00713631970.011
dna repairGO:00062811980.011
multi organism cellular processGO:00447641560.011
thymus developmentGO:004853830.011
cell projection morphogenesisGO:00488581290.011
positive regulation of cell motilityGO:20001471770.011
response to radiationGO:00093141510.011
positive regulation of ras gtpase activityGO:00323201170.011
Human
regulation of growthGO:00400081650.011
Human
cellular divalent inorganic cation homeostasisGO:00725031280.011
negative regulation of cell migrationGO:00303361020.011
regulation of sequence specific dna binding transcription factor activityGO:00510902110.011
regulation of protein modification by small protein conjugation or removalGO:19033201070.011
endosomal transportGO:00161971290.011
cardiac muscle contractionGO:0060048340.011
neuron developmentGO:00486661130.011
neural tube formationGO:000184130.011
behaviorGO:00076101120.011
cell morphogenesis involved in differentiationGO:00009041440.011
phospholipid metabolic processGO:0006644990.011
regulation of homeostatic processGO:00328441210.011
glycoprotein biosynthetic processGO:0009101910.011
startle responseGO:000196430.011
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.011
myoblast fusionGO:000752010.011
organic anion transportGO:00157111030.011
release of cytoplasmic sequestered nf kappabGO:000858840.011
negative regulation of locomotionGO:00400131180.011
regulation of protein complex assemblyGO:00432541470.011
calcium ion homeostasisGO:00550741220.011
cerebellum developmentGO:002154920.011
response to woundingGO:00096111680.011
regulation of reactive oxygen species metabolic processGO:2000377410.011
immune effector processGO:00022521590.011
positive regulation of cellular component biogenesisGO:00440891580.011
regulation of cell developmentGO:00602841610.011
g protein coupled receptor signaling pathwayGO:00071862070.011
immune system developmentGO:00025201950.010
glycerophospholipid metabolic processGO:0006650840.010
establishment of protein localization to membraneGO:00901501210.010
regulation of phosphatase activityGO:0010921810.010
inner ear morphogenesisGO:004247240.010
divalent metal ion transportGO:00708381520.010
epithelial cell proliferationGO:00506731280.010
sensory perception of painGO:001923340.010
response to lipidGO:00339932060.010
positive regulation of reactive oxygen species metabolic processGO:2000379240.010
leukocyte activationGO:00453211640.010
behavioral response to ethanolGO:004814920.010
morphogenesis of a polarized epitheliumGO:000173830.010
regulation of protein transportGO:00512232130.010
cellular amide metabolic processGO:0043603690.010
cellular potassium ion transportGO:0071804600.010
negative regulation of transferase activityGO:00513481240.010
negative regulation of synaptic transmissionGO:005080520.010
protein oligomerizationGO:00512591730.010
cellular calcium ion homeostasisGO:00068741170.010
regulation of transporter activityGO:0032409820.010
somatic stem cell maintenanceGO:003501940.010
organelle localizationGO:0051640840.010
meiosis iGO:000712740.010
nucleus localizationGO:005164710.010
negative regulation of cell differentiationGO:00455961710.010
peptidyl tyrosine phosphorylationGO:00181081700.010
response to oxygen levelsGO:00704821000.010
wnt signaling pathwayGO:00160551560.010
neuron projection developmentGO:00311751060.010
neuron projection regenerationGO:003110210.010
regulation of cell projection organizationGO:00313441070.010
regulation of meiosisGO:004002030.010
mrna metabolic processGO:00160711750.010
fatty acid metabolic processGO:00066311150.010

PRUNE2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.030
central nervous system diseaseDOID:3311860.028
nervous system diseaseDOID:8634310.028
sensory system diseaseDOID:00501552030.024
disease of cellular proliferationDOID:145661740.023
disease of metabolismDOID:00146672950.023
cancerDOID:1621670.021
organ system cancerDOID:00506861640.020
eye diseaseDOID:56141490.019
eye and adnexa diseaseDOID:14921500.019
connective tissue diseaseDOID:651090.015
inherited metabolic disorderDOID:6552420.015
muscular diseaseDOID:00800001140.015
muscle tissue diseaseDOID:661130.015
retinal diseaseDOID:56791180.015
myopathyDOID:4231040.014
neurodegenerative diseaseDOID:12891020.013
cardiovascular system diseaseDOID:12871060.013
brain diseaseDOID:936730.013
bone diseaseDOID:0080001880.012
retinal degenerationDOID:8466890.011
immune system diseaseDOID:29141550.011