Homo sapiens

143 known processes

SMURF1

SMAD specific E3 ubiquitin protein ligase 1

(Aliases: KIAA1625)

SMURF1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015481.000
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781251.000
negative regulation of sodium ion transmembrane transportGO:190230620.998
Human
enzyme linked receptor protein signaling pathwayGO:00071673030.996
regulation of mrna export from nucleusGO:001079330.989
Yeast
bmp signaling pathwayGO:0030509490.988
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.987
cellular response to endogenous stimulusGO:00714953360.983
regulation of ketone biosynthetic processGO:001056670.982
Yeast
negative regulation of sodium ion transmembrane transporter activityGO:200065020.976
Human
development involved in symbiotic interactionGO:004411110.975
Human
positive regulation of dna templated transcription elongationGO:0032786180.974
tube developmentGO:00352951250.974
Fly
response to growth factorGO:00708482050.973
polyprenol biosynthetic processGO:001609410.965
Yeast
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090100410.963
stem cell divisionGO:001714520.962
negative regulation of sodium ion transportGO:001076630.957
Human
regulation of rrna processingGO:200023210.939
Yeast
cell cycle arrestGO:0007050710.931
negative regulation of cell deathGO:00605483450.927
Human
positive regulation of apoptotic processGO:00430652460.916
protein autoubiquitinationGO:0051865370.916
Human Yeast
histone h3 acetylationGO:0043966450.912
negative regulation of potassium ion transmembrane transportGO:190138050.911
Human
ribosomal large subunit export from nucleusGO:000005530.911
Yeast
regulation of cell differentiationGO:00455953930.908
regulation of activin receptor signaling pathwayGO:0032925140.904
transmission of virusGO:001908910.901
Human
ubiquitin dependent protein catabolic processGO:00065112060.897
dissemination or transmission of symbiont from hostGO:004400710.896
Human
negative regulation of apoptotic processGO:00430663160.891
Human
regulation of dna templated transcription in response to stressGO:0043620180.868
Human
negative regulation of chromatin silencingGO:003193640.861
establishment of ribosome localizationGO:003375340.849
Yeast
cell proliferation involved in heart valve developmentGO:200079310.845
protein ubiquitinationGO:00165673140.844
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulusGO:190152220.843
protein k63 linked ubiquitinationGO:0070534310.835
Human
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.830
Human
chromatin silencing at rdnaGO:000018350.828
positive regulation of bmp signaling pathwayGO:003051390.826
transforming growth factor beta receptor signaling pathwayGO:0007179760.826
protein acylationGO:00435431380.820
regulation of cellular response to growth factor stimulusGO:0090287760.818
chromatin modificationGO:00165682980.807
positive regulation of transcription from rna polymerase ii promoter in response to stressGO:003600390.803
cellular response to transforming growth factor beta stimulusGO:0071560940.788
asymmetric stem cell divisionGO:009872210.764
polyprenol metabolic processGO:001609330.763
Yeast
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101450.761
regulation of sequence specific dna binding transcription factor activityGO:00510902110.751
positive regulation of osteoblast differentiationGO:0045669230.750
positive regulation of cell differentiationGO:00455972110.749
oxidoreduction coenzyme metabolic processGO:0006733190.734
Yeast
negative regulation of transcription from rna polymerase ii promoter in response to uv induced dna damageGO:001076810.725
Human
coenzyme biosynthetic processGO:0009108240.725
Yeast
dolichol metabolic processGO:001934830.724
Yeast
actin filament based movementGO:0030048170.723
cellular response to growth factor stimulusGO:00713631970.717
regulation of multivesicular body sizeGO:001079610.709
Yeast
isoprenoid metabolic processGO:0006720390.696
Yeast
vacuolar transportGO:0007034340.684
Human Yeast
response to external biotic stimulusGO:00432072610.683
Human
rrna containing ribonucleoprotein complex export from nucleusGO:007142840.670
Yeast
regulation of cofactor metabolic processGO:005119330.648
Yeast
positive regulation of cell deathGO:00109422630.645
endosome transport via multivesicular body sorting pathwayGO:003250930.645
Yeast
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.640
response to biotic stimulusGO:00096072760.631
Human
cellular ketone metabolic processGO:0042180800.621
Yeast
trna export from nucleusGO:000640910.618
Yeast
meiosis iGO:000712740.617
intracellular protein transportGO:00068862700.608
positive regulation of programmed cell deathGO:00430682490.602
blood vessel developmentGO:00015681720.597
growthGO:00400072020.594
Fly
transcription from rna polymerase i promoterGO:0006360110.585
positive regulation of protein phosphorylationGO:00019343130.572
mitotic cell cycleGO:00002783260.561
cellular protein catabolic processGO:00442572610.558
negative regulation of pathway restricted smad protein phosphorylationGO:0060394110.549
digestive tract morphogenesisGO:0048546560.548
Fly
regulation of cell cycleGO:00517263930.535
dissemination or transmission of organism from other organism involved in symbiotic interactionGO:005182110.522
Human
regulation of transcription from rna polymerase ii promoter in response to uv induced dna damageGO:001076710.518
Human
negative regulation of cellular response to growth factor stimulusGO:0090288410.514
mitotic cell cycle phase transitionGO:00447721620.514
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512280.511
histone acetylationGO:0016573930.508
ubiquitin dependent smad protein catabolic processGO:003057940.505
quinone biosynthetic processGO:190166360.492
Yeast
i kappab kinase nf kappab signalingGO:00072491660.489
ribosomal subunit export from nucleusGO:000005440.486
Yeast
positive regulation of transcription elongation from rna polymerase ii promoterGO:0032968100.485
mesodermal cell fate commitmentGO:000171020.483
anatomical structure formation involved in morphogenesisGO:00486462840.481
Yeast Fly
response to transforming growth factor betaGO:0071559940.481
negative regulation of chromatin silencing at rdnaGO:006118820.479
positive regulation of cytoplasmic transportGO:1903651820.471
Human
activin receptor signaling pathwayGO:0032924240.468
negative regulation of potassium ion transmembrane transporter activityGO:190101730.462
Human
negative regulation of bmp signaling pathwayGO:0030514170.459
Fly
cell adhesionGO:00071553250.458
system processGO:00030083490.458
embryonic morphogenesisGO:0048598850.453
Fly
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetryGO:190016410.452
cell developmentGO:00484683280.448
Human Fly
epithelium developmentGO:00604292270.447
regulation of endosome sizeGO:005103630.441
Yeast
cellular macromolecule catabolic processGO:00442653800.440
cellular amine metabolic processGO:0044106410.440
cell cycle phase transitionGO:00447701730.432
potassium ion transmembrane transportGO:0071805600.429
Human
positive regulation of map kinase activityGO:0043406800.427
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238260.425
quinone metabolic processGO:1901661180.423
Yeast
histone h4 k8 acetylationGO:0043982150.417
interaction with hostGO:0051701420.417
Human
regulation of protein catabolic processGO:00421761550.396
Human Yeast
regulation of mesoderm developmentGO:200038040.394
response to other organismGO:00517072610.390
Human
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.388
positive regulation of stress activated protein kinase signaling cascadeGO:0070304610.386
proteolysis involved in cellular protein catabolic processGO:00516032440.376
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiationGO:000325730.376
negative regulation of cell proliferationGO:00082852280.374
internal peptidyl lysine acetylationGO:0018393970.371
regulation of cytokine productionGO:00018172320.364
response to abiotic stimulusGO:00096283360.361
Human Yeast
zygotic specification of dorsal ventral axisGO:000735220.358
regulation of protein serine threonine kinase activityGO:00719001790.354
positive regulation of myeloid leukocyte differentiationGO:0002763240.354
establishment of rna localizationGO:0051236390.353
Yeast
regulation of endothelial cell migrationGO:0010594670.351
ras protein signal transductionGO:0007265730.346
regulation of transcription from rna polymerase ii promoter in response to stressGO:0043618170.342
Human
heart valve formationGO:000318820.337
chromatin assembly or disassemblyGO:0006333780.335
Yeast
neuromuscular junction developmentGO:000752830.334
trna processingGO:0008033230.332
Yeast
extrinsic apoptotic signaling pathwayGO:00971911190.329
peptidyl lysine acetylationGO:00183941010.329
sperm motilityGO:003031760.327
endocardial cushion developmentGO:000319730.325
protein targeting to vacuoleGO:000662380.319
Human
nuclear divisionGO:00002801280.316
common partner smad protein phosphorylationGO:000718230.316
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.316
lysosomal transportGO:0007041330.316
Human
ameboidal type cell migrationGO:00016671350.315
apoptotic signaling pathwayGO:00971902680.310
ribonucleoprotein complex localizationGO:007116640.310
Yeast
regulation of proteasomal protein catabolic processGO:0061136870.307
Yeast
peptidyl lysine modificationGO:00182051440.306
lateral mesoderm developmentGO:004836810.306
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436300.304
Yeast
receptor metabolic processGO:0043112810.302
positive regulation of cellular catabolic processGO:00313312840.302
Yeast
epithelial to mesenchymal transitionGO:0001837480.299
regulation of immune effector processGO:0002697910.299
Human
amine metabolic processGO:0009308440.296
regulation of apoptotic signaling pathwayGO:20012331750.295
positive regulation of jnk cascadeGO:0046330520.295
histone h4 k5 acetylationGO:0043981150.294
regulation of growthGO:00400081650.293
Fly
negative regulation of cellular amine metabolic processGO:003323930.291
regulation of transcription elongation from rna polymerase ii promoterGO:0034243130.291
positive regulation of stem cell differentiationGO:2000738290.288
multi organism cellular processGO:00447641560.287
Human Yeast
positive regulation of proteolysisGO:00458621420.285
Yeast
regulation of ribosome biogenesisGO:009006910.281
Yeast
lipid localizationGO:00108761060.278
fatty acid biosynthetic processGO:0006633460.276
Yeast
negative regulation of transporter activityGO:0032410250.275
Human
cofactor metabolic processGO:0051186870.273
Yeast
regulation of transferase activityGO:00513383550.272
negative regulation of ion transportGO:0043271390.271
Human
modification dependent protein catabolic processGO:00199412090.270
intracellular receptor signaling pathwayGO:00305221040.269
Human
regulation of protein kinase activityGO:00458592890.269
hard palate developmentGO:006002210.266
isoprenoid biosynthetic processGO:000829990.263
Yeast
immune responseGO:00069553070.258
regulation of i kappab kinase nf kappab signalingGO:00431221620.257
regulation of epithelial to mesenchymal transitionGO:0010717370.256
positive regulation of developmental processGO:00510943140.255
positive regulation of proteasomal protein catabolic processGO:1901800350.254
Yeast
positive regulation of fatty acid biosynthetic processGO:004572350.251
Yeast
male meiosisGO:000714010.250
maintenance of locationGO:00512351120.248
single organism cell adhesionGO:00986021790.247
receptor catabolic processGO:0032801110.245
regulation of mapk cascadeGO:00434082620.240
regulation of cellular ketone metabolic processGO:0010565500.240
Yeast
cofactor biosynthetic processGO:0051188310.239
Yeast
tube morphogenesisGO:0035239950.234
Fly
positive regulation of catabolic processGO:00098963100.232
Human Yeast
immune response regulating cell surface receptor signaling pathwayGO:0002768510.232
chromatin organizationGO:00063253510.231
Yeast
mitotic cell cycle processGO:19030472860.231
mrna transportGO:0051028300.230
Yeast
organic hydroxy compound metabolic processGO:19016151470.228
Yeast
cellular lipid metabolic processGO:00442553030.228
Yeast
blood vessel morphogenesisGO:00485141620.226
modification dependent macromolecule catabolic processGO:00436322120.226
nodal signaling pathway involved in determination of left right asymmetryGO:003810710.224
bleb assemblyGO:003206060.223
negative regulation of growthGO:0045926970.222
ribosome localizationGO:003375040.219
Yeast
positive regulation of jun kinase activityGO:0043507230.218
carboxylic acid biosynthetic processGO:0046394970.215
Yeast
regulation of potassium ion transportGO:0043266240.213
Human
protein catabolic processGO:00301633250.212
regulation of cellular component sizeGO:0032535820.210
Yeast
positive regulation of hydrolase activityGO:00513453310.208
positive regulation of protein bindingGO:0032092240.207
spermatid differentiationGO:004851540.205
reactive nitrogen species metabolic processGO:200105730.203
immune response activating cell surface receptor signaling pathwayGO:0002429450.203
negative regulation of cell differentiationGO:00455961710.200
regulation of cell adhesionGO:00301551660.200
regulation of anatomical structure morphogenesisGO:00226032860.200
Yeast
single organism cellular localizationGO:19025803320.197
Human
negative regulation of apoptotic signaling pathwayGO:2001234970.197
dolichol biosynthetic processGO:001940810.195
Yeast
biological adhesionGO:00226103310.194
negative regulation of cell growthGO:0030308830.193
negative regulation of programmed cell deathGO:00430693210.193
Human
regulation of actin cytoskeleton organizationGO:00329561160.192
Yeast
regulation of stress activated mapk cascadeGO:0032872840.188
positive regulation of apoptotic signaling pathwayGO:2001235700.188
response to interleukin 1GO:0070555470.187
morphogenesis of embryonic epitheliumGO:001633140.186
regulation of ectodermal cell fate specificationGO:004266510.185
regulation of protein ubiquitinationGO:0031396950.185
regulation of gene silencingGO:0060968240.182
evasion or tolerance of host defensesGO:004441520.182
lipid biosynthetic processGO:00086101770.181
Yeast
somitogenesisGO:000175620.181
negative regulation of multicellular organismal processGO:00512413170.180
Mouse
negative regulation of protein modification processGO:00314002000.178
regulation of adaptive immune responseGO:0002819330.178
gastrulationGO:0007369510.178
regulation of chromatin silencing at rdnaGO:006118720.177
glycosyl compound catabolic processGO:19016584130.177
stem cell developmentGO:0048864690.177
neural crest cell developmentGO:001403230.175
negative regulation of transcription from rna polymerase i promoterGO:001647920.172
regulation of kinase activityGO:00435493140.171
proteasomal protein catabolic processGO:00104981760.171
regulation of ectoderm developmentGO:200038310.171
negative regulation of protein metabolic processGO:00512483910.171
ncrna metabolic processGO:00346601080.170
Yeast
cell divisionGO:00513011680.169
mesodermal cell fate specificationGO:000750120.169
regulation of nodal signaling pathway involved in determination of left right asymmetryGO:190014510.169
oogenesisGO:004847720.168
Fly
response to organic cyclic compoundGO:00140702040.168
regulation of cell morphogenesis involved in differentiationGO:0010769830.167
positive regulation of stress activated mapk cascadeGO:0032874600.167
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.166
Yeast
cellular response to oxygen containing compoundGO:19017012760.165
small molecule biosynthetic processGO:00442831570.165
Yeast
potassium ion transportGO:0006813620.164
Human
regulation of jun kinase activityGO:0043506270.163
ribonucleoprotein complex export from nucleusGO:007142640.162
Yeast
histone h4 acetylationGO:0043967470.161
membrane repolarizationGO:0086009230.159
Human
mesenchymal cell developmentGO:0014031500.158
negative regulation of developmental processGO:00510932470.158
transcription elongation from rna polymerase ii promoterGO:0006368180.157
autophagyGO:0006914880.157
Yeast
female gamete generationGO:000729220.157
Fly
regulation of nucleocytoplasmic transportGO:0046822980.155
Human Yeast
purine nucleoside catabolic processGO:00061523980.155
regulation of proteolysisGO:00301622930.155
Yeast
positive regulation of immune system processGO:00026842830.155
dna damage response signal transduction resulting in transcriptionGO:0042772120.153
regulation of cytokine production involved in immune responseGO:0002718220.152
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002460400.151
regulation of protein localization to cell surfaceGO:2000008150.150
Human
negative regulation of ion transmembrane transportGO:0034766260.149
Human
protein homooligomerizationGO:00512601000.148
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787370.144
multicellular organismal agingGO:001025930.143
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052350.143
Yeast
monovalent inorganic cation transportGO:00156721280.142
Human
cell cycle g2 m phase transitionGO:0044839430.141
coenzyme metabolic processGO:0006732650.140
Yeast
regulation of actin filament based processGO:00329701410.139
Yeast
protein localization to lysosomeGO:0061462110.139
Human
negative regulation of protein localization to cell surfaceGO:200000950.139
Human
stem cell differentiationGO:0048863930.138
regulation of protein bindingGO:0043393660.137
spermatid developmentGO:000728640.136
nuclear transportGO:00511691790.135
maintenance of cell polarityGO:003001120.134
positive regulation of myeloid cell differentiationGO:0045639390.134
positive regulation of epithelial to mesenchymal transitionGO:0010718220.133
cellular response to histamineGO:007142030.133
response to inorganic substanceGO:00100351270.133
Human
histone h4 k12 acetylationGO:004398360.132
negative regulation of cellular component organizationGO:00511292350.132
circulatory system developmentGO:00723592620.131
positive regulation of canonical wnt signaling pathwayGO:0090263330.130
signal transduction in response to dna damageGO:0042770570.129
scf dependent proteasomal ubiquitin dependent protein catabolic processGO:0031146150.129
nervous system developmentGO:00073992930.129
Human
positive regulation of transforming growth factor beta receptor signaling pathwayGO:0030511120.128
lipid metabolic processGO:00066293810.124
Yeast
regulation of meiotic cell cycleGO:005144540.123
negative regulation of cell cycleGO:00457861930.123
cellular amino acid metabolic processGO:00065201160.123
sodium ion transportGO:0006814610.122
Human
cell morphogenesis involved in differentiationGO:00009041440.122
nuclear exportGO:0051168690.122
protein modification by small protein conjugationGO:00324463420.121
embryo developmentGO:00097901230.120
Fly
immune response activating signal transductionGO:0002757900.120
positive regulation of mapk cascadeGO:00434101900.120
regulation of cell developmentGO:00602841610.119
regulation of chromatin silencingGO:003193580.118
positive regulation of bindingGO:0051099450.117
dna templated transcription elongationGO:0006354250.117
cellular potassium ion transportGO:0071804600.117
Human
negative regulation of gastrulationGO:200054240.116
dna damage response signal transduction by p53 class mediatorGO:0030330440.115
ectodermal cell fate specificationGO:000171510.115
t cell cytokine productionGO:0002369120.115
positive regulation of cytokine productionGO:00018191670.115
positive regulation of transportGO:00510503360.114
Human Yeast
response to hostGO:007513620.113
metal ion transportGO:00300012720.113
Human
phosphatidylinositol mediated signalingGO:0048015550.112
Human
regulation of phosphatidylinositol 3 kinase signalingGO:0014066350.112
Human
protein acetylationGO:00064731160.111
positive regulation of gtpase activityGO:00435471660.110
dna replicationGO:00062601160.110
endosomal transportGO:00161971290.110
Yeast
positive regulation of cellular protein catabolic processGO:1903364370.109
Yeast
internal protein amino acid acetylationGO:00064751010.109
actin mediated cell contractionGO:0070252120.109
activation of immune responseGO:00022531140.108
negative regulation of catalytic activityGO:00430863350.107
regulation of receptor mediated endocytosisGO:0048259320.107
Yeast
intracellular steroid hormone receptor signaling pathwayGO:0030518610.107
Human
positive regulation of amine transportGO:005195420.106
negative regulation of nf kappab transcription factor activityGO:0032088510.105
negative regulation of potassium ion transportGO:004326760.104
Human
ectoderm developmentGO:000739830.104
chemical homeostasisGO:00488783060.103
Human
chemotaxisGO:00069351570.103
positive regulation of nucleocytoplasmic transportGO:0046824540.103
Human
positive regulation of protein kinase activityGO:00458601900.103
regulation of cellular component movementGO:00512703340.102
regulation of epithelial cell migrationGO:0010632930.102
cytoplasmic transportGO:00164823790.101
nitrogen compound transportGO:00717051910.101
Yeast
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.101
mesenchymal cell differentiationGO:0048762520.101
cell migration involved in gastrulationGO:004207410.100
respiratory gaseous exchangeGO:000758530.100
mesodermal cell differentiationGO:0048333100.100
immune effector processGO:00022521590.100
Human
phosphatidylinositol 3 kinase signalingGO:0014065480.099
Human
regulation of bmp signaling pathwayGO:0030510270.099
Fly
regulation of isoprenoid metabolic processGO:001974710.098
Yeast
response to fluid shear stressGO:0034405140.098
single organism reproductive processGO:0044702980.097
Yeast Fly
positive regulation of kinase activityGO:00336742040.097
regulation of osteoblast differentiationGO:0045667380.096
antigen receptor mediated signaling pathwayGO:0050851380.096
trna transportGO:005103110.096
Yeast
negative regulation of gliogenesisGO:001401430.094
gene silencingGO:0016458490.093
regulation of stem cell differentiationGO:2000736560.093
formation of primary germ layerGO:0001704420.093
mesoderm developmentGO:0007498140.092
regulation of ligase activityGO:0051340290.091
digestive tract developmentGO:0048565750.091
Fly
regulation of protein homodimerization activityGO:004349690.091
regulation of lymphocyte mediated immunityGO:0002706330.091
t cell receptor signaling pathwayGO:0050852210.090
cell fate commitment involved in formation of primary germ layerGO:006079560.089
wnt signaling pathwayGO:00160551560.089
cation transportGO:00068123310.087
Human
regulation of nodal signaling pathway involved in determination of lateral mesoderm left right asymmetryGO:190017510.087
trna metabolic processGO:0006399350.087
Yeast
response to nitrogen compoundGO:19016981840.086
reproductive processGO:00224141060.086
Yeast Fly
positive regulation of cellular component organizationGO:00511303760.086
Yeast
cytokine productionGO:00018162470.085
epithelial cell migrationGO:00106311190.084
angiogenesisGO:00015251470.084
regulation of jnk cascadeGO:0046328730.084
histone modificationGO:00165702510.084
male gonad developmentGO:0008584230.082
neuron fate commitmentGO:004866320.082
hemoglobin biosynthetic processGO:004254130.082
negative regulation of mesodermal cell fate specificationGO:004266210.082
regulation of peptidase activityGO:00525471800.081
regulation of dna templated transcription elongationGO:0032784230.081
positive regulation of cell adhesionGO:0045785840.081
regulation of cell migrationGO:00303342890.080
response to organonitrogen compoundGO:00102431560.080
g2 m transition of mitotic cell cycleGO:0000086410.080
smad protein complex assemblyGO:0007183120.080
adaptive immune responseGO:0002250490.079
rho protein signal transductionGO:0007266260.079
positive regulation of gene expression epigeneticGO:004581570.077
oocyte differentiationGO:000999420.077
regulation of membrane depolarizationGO:0003254190.077
Human
single organismal cell cell adhesionGO:00163371480.077
cell projection organizationGO:00300302520.077
Human Yeast
cellular component morphogenesisGO:00329893140.076
Yeast
response to host defensesGO:005220020.076
mrna export from nucleusGO:0006406290.076
Yeast
positive regulation of protein ubiquitinationGO:0031398530.076
regulation of metal ion transportGO:00109591200.076
Human
regulation of cell cell adhesionGO:0022407570.075
atrioventricular valve developmentGO:000317130.075
oocyte developmentGO:004859910.075
segmentationGO:003528240.075
meiotic cell cycleGO:0051321130.074
regulation of leukocyte mediated immunityGO:0002703380.074
positive regulation of protein catabolic processGO:0045732750.074
Human Yeast
positive regulation of wnt signaling pathwayGO:0030177540.074
symbiosis encompassing mutualism through parasitismGO:00444031560.074
Human
positive regulation of ras gtpase activityGO:00323201170.074
ossification involved in bone maturationGO:004393140.073
mesoderm morphogenesisGO:0048332110.073
negative regulation of immune effector processGO:0002698380.073
Human
multicellular organism reproductionGO:0032504420.072
Fly
circadian behaviorGO:004851220.072
mesenchyme developmentGO:0060485590.072
developmental process involved in reproductionGO:0003006660.071
Yeast Fly
regulation of neural precursor cell proliferationGO:200017740.071
regulation of hemoglobin biosynthetic processGO:004698410.071
cellular response to dna damage stimulusGO:00069743790.070
determination of left right asymmetry in lateral mesodermGO:000314010.070
protein targetingGO:00066051870.069
Human
regulation of endopeptidase activityGO:00525481700.069
purine nucleotide catabolic processGO:00061954050.068
regulation of cell morphogenesisGO:00226041530.068
Yeast
positive regulation of nf kappab transcription factor activityGO:0051092810.067
negative regulation of phosphorylationGO:00423261740.067
regulation of transcription regulatory region dna bindingGO:2000677150.066
regulation of pathway restricted smad protein phosphorylationGO:0060393340.066
protein oligomerizationGO:00512591730.066
actin cytoskeleton organizationGO:00300362070.065
Yeast
nucleocytoplasmic transportGO:00069131760.064
sebaceous gland developmentGO:004873310.064
negative regulation of blood vessel morphogenesisGO:2000181410.064
regulation of establishment of protein localizationGO:00702012420.063
Human
negative regulation of cellular amino acid metabolic processGO:004576320.063
regulation of ras protein signal transductionGO:00465781550.063
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237520.063
regulation of gene expression epigeneticGO:0040029730.062
inositol lipid mediated signalingGO:0048017550.062
Human
progesterone receptor signaling pathwayGO:005084730.062
Human
regulation of nodal signaling pathwayGO:190010710.062
evasion or tolerance of host defenses by virusGO:001904920.062
cell part morphogenesisGO:00329901370.062
fatty acid metabolic processGO:00066311150.061
Yeast
positive regulation of protein serine threonine kinase activityGO:00719021190.061
positive regulation of lymphocyte mediated immunityGO:0002708230.061
organelle fissionGO:00482851490.061
mesoderm formationGO:0001707100.061
regulation of sodium ion transportGO:0002028240.061
Human
signal transduction by phosphorylationGO:00230142970.060
alcohol metabolic processGO:00060661140.060
Yeast
maintenance of protein location in cellGO:0032507560.060
regulation of cytoskeleton organizationGO:00514931770.060
Yeast
regulation of gtp catabolic processGO:00331241800.060
response to lipidGO:00339932060.059
cellular response to tumor necrosis factorGO:0071356630.059
positive regulation of rho protein signal transductionGO:003502540.058
regulation of immune responseGO:00507762010.058
defense response to other organismGO:00985421290.057
Human
positive regulation of chondrocyte differentiationGO:003233240.057
vasculature developmentGO:00019441810.057
somatic stem cell divisionGO:004810310.057
positive regulation of phosphorylationGO:00423273940.056
regulation of glial cell proliferationGO:006025140.056
ubiquitin dependent endocytosisGO:007008610.056
Yeast
rna export from nucleusGO:0006405330.056
Yeast
regulation of cysteine type endopeptidase activityGO:20001161270.056
interspecies interaction between organismsGO:00444191560.056
Human
regulation of alcohol biosynthetic processGO:1902930220.056
Yeast
regulation of ion transportGO:00432691890.056
Human
hematopoietic or lymphoid organ developmentGO:00485341860.056

SMURF1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.118
connective tissue diseaseDOID:651090.100
bone diseaseDOID:0080001880.085
cancerDOID:1621670.076
disease of cellular proliferationDOID:145661740.076
organ system cancerDOID:00506861640.076