Homo sapiens

43 known processes

SMURF2

SMAD specific E3 ubiquitin protein ligase 2

(Aliases: MGC138150,DKFZp686F0270)

SMURF2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of ketone biosynthetic processGO:001056671.000
Yeast
development involved in symbiotic interactionGO:004411111.000
Human
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512281.000
Human
negative regulation of sodium ion transmembrane transportGO:190230621.000
Human
polyprenol biosynthetic processGO:001609411.000
Yeast
regulation of mrna export from nucleusGO:001079331.000
Yeast
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781251.000
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101451.000
Human Fly
negative regulation of sodium ion transportGO:001076631.000
Human
dissemination or transmission of organism from other organism involved in symbiotic interactionGO:005182111.000
Human
regulation of endosome sizeGO:005103631.000
Yeast
transforming growth factor beta receptor signaling pathwayGO:0007179761.000
Human Fly
negative regulation of sodium ion transmembrane transporter activityGO:200065021.000
Human
positive regulation of proteasomal protein catabolic processGO:1901800351.000
Yeast
response to transforming growth factor betaGO:0071559941.000
Human Fly
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015481.000
Human
bmp signaling pathwayGO:0030509491.000
Human Fly
transmission of virusGO:001908911.000
Human
dolichol biosynthetic processGO:001940811.000
Yeast
regulation of ribosome biogenesisGO:009006911.000
Yeast
polyprenol metabolic processGO:001609331.000
Yeast
regulation of pathway restricted smad protein phosphorylationGO:0060393341.000
trna export from nucleusGO:000640911.000
Yeast
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092901.000
Human Fly
negative regulation of bmp signaling pathwayGO:0030514171.000
Fly
dissemination or transmission of symbiont from hostGO:004400711.000
Human
regulation of cellular response to growth factor stimulusGO:0090287761.000
Human
dolichol metabolic processGO:001934831.000
Yeast
smad protein complex assemblyGO:0007183121.000
regulation of activin receptor signaling pathwayGO:0032925141.000
regulation of rrna processingGO:200023211.000
Yeast
negative regulation of potassium ion transmembrane transporter activityGO:190101731.000
Human
rrna containing ribonucleoprotein complex export from nucleusGO:007142841.000
Yeast
cellular response to endogenous stimulusGO:00714953360.999
Human Fly
ribosomal large subunit export from nucleusGO:000005530.999
Yeast
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.999
Yeast
regulation of proteasomal protein catabolic processGO:0061136870.999
Yeast
establishment of ribosome localizationGO:003375340.999
Yeast
cellular response to transforming growth factor beta stimulusGO:0071560940.999
Human Fly
ubiquitin dependent smad protein catabolic processGO:003057940.999
protein polyubiquitinationGO:00002091100.999
Human Yeast
positive regulation of nucleocytoplasmic transportGO:0046824540.999
Human
regulation of multivesicular body sizeGO:001079610.999
Yeast
evasion or tolerance of host defensesGO:004441520.999
regulation of transcription from rna polymerase ii promoter in response to uv induced dna damageGO:001076710.999
Human
regulation of membrane repolarizationGO:0060306160.999
Human
modification dependent macromolecule catabolic processGO:00436322120.998
protein modification by small protein conjugationGO:00324463420.998
potassium ion transportGO:0006813620.998
Human
positive regulation of cytoplasmic transportGO:1903651820.998
Human
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436300.998
Yeast
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052350.998
Yeast
pathway restricted smad protein phosphorylationGO:0060389380.997
avoidance of defenses of other organism involved in symbiotic interactionGO:005183220.997
response to biotic stimulusGO:00096072760.997
Human
negative regulation of cellular response to growth factor stimulusGO:0090288410.997
Human
oxidoreduction coenzyme metabolic processGO:0006733190.997
Yeast
retinal ganglion cell axon guidanceGO:003129020.997
nuclear transportGO:00511691790.997
Human Yeast
positive regulation of catabolic processGO:00098963100.997
Human Yeast
response to growth factorGO:00708482050.997
Human Fly
interaction with hostGO:0051701420.997
Human
positive regulation of proteolysisGO:00458621420.997
Yeast
ubiquitin dependent endocytosisGO:007008610.996
Yeast
regulation of isoprenoid metabolic processGO:001974710.996
Yeast
potassium ion transmembrane transportGO:0071805600.996
Human
positive regulation of fatty acid biosynthetic processGO:004572350.996
Yeast
positive regulation of bmp signaling pathwayGO:003051390.996
regulation of potassium ion transmembrane transporter activityGO:1901016160.996
Human
common partner smad protein phosphorylationGO:000718230.995
coenzyme biosynthetic processGO:0009108240.995
Yeast
regulation of nucleocytoplasmic transportGO:0046822980.994
Human Yeast
protein localization to lysosomeGO:0061462110.994
Human
protein k29 linked ubiquitinationGO:003551940.994
Human
trna transportGO:005103110.994
Yeast
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.994
Human
regulation of cytoplasmic transportGO:19036491490.994
Human Yeast
activin receptor signaling pathwayGO:0032924240.993
positive regulation of protein catabolic processGO:0045732750.993
Human Yeast
positive regulation of stem cell differentiationGO:2000738290.993
receptor catabolic processGO:0032801110.993
Human
regulation of coenzyme metabolic processGO:005119630.993
Yeast
multi organism cellular processGO:00447641560.992
Human Yeast
enzyme linked receptor protein signaling pathwayGO:00071673030.992
protein k48 linked ubiquitinationGO:0070936380.991
Human
chromatin assembly or disassemblyGO:0006333780.990
Yeast
interspecies interaction between organismsGO:00444191560.990
Human
neuron projection developmentGO:00311751060.989
Human
positive regulation of intracellular transportGO:00323881040.989
Human
protein ubiquitinationGO:00165673140.988
regulation of cellular protein catabolic processGO:1903362960.987
Yeast
isoprenoid biosynthetic processGO:000829990.987
Yeast
nucleocytoplasmic transportGO:00069131760.987
Human Yeast
negative regulation of protein localization to cell surfaceGO:200000950.986
Human
ribosomal subunit export from nucleusGO:000005440.985
Yeast
quinone biosynthetic processGO:190166360.984
Yeast
evasion or tolerance of defenses of other organism involved in symbiotic interactionGO:005183420.983
ribonucleoprotein complex localizationGO:007116640.983
Yeast
regulation of epithelial to mesenchymal transitionGO:0010717370.983
cellular response to growth factor stimulusGO:00713631970.982
Human Fly
steroid biosynthetic processGO:0006694460.982
Yeast
stem cell differentiationGO:0048863930.981
response to other organismGO:00517072610.981
Human
endosome transport via multivesicular body sorting pathwayGO:003250930.979
Yeast
mesenchymal cell developmentGO:0014031500.979
regulation of establishment of protein localizationGO:00702012420.979
Human
modification dependent protein catabolic processGO:00199412090.978
cell junction assemblyGO:0034329670.977
regulation of cellular ketone metabolic processGO:0010565500.977
Yeast
regulation of bmp signaling pathwayGO:0030510270.976
Fly
regulation of steroid biosynthetic processGO:0050810230.976
Yeast
regulation of potassium ion transmembrane transportGO:1901379200.975
Human
neuron differentiationGO:00301821380.975
Human
negative regulation of peptidyl threonine phosphorylationGO:001080160.974
stem cell developmentGO:0048864690.974
quinone metabolic processGO:1901661180.973
Yeast
regulation of cofactor metabolic processGO:005119330.973
Yeast
protein k63 linked ubiquitinationGO:0070534310.973
Human
inorganic ion transmembrane transportGO:00986602310.973
Human
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.972
Human Yeast
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.970
endosomal transportGO:00161971290.970
Yeast
positive regulation of cellular protein catabolic processGO:1903364370.967
Yeast
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetryGO:190016410.966
lysosomal transportGO:0007041330.965
Human
protein catabolic processGO:00301633250.965
protein localization to organelleGO:00333652800.965
Human
proteolysis involved in cellular protein catabolic processGO:00516032440.964
ubiquitin dependent protein catabolic processGO:00065112060.961
zygotic specification of dorsal ventral axisGO:000735220.961
evasion or tolerance of host defenses by virusGO:001904920.961
positive regulation of cellular catabolic processGO:00313312840.960
Yeast
symbiosis encompassing mutualism through parasitismGO:00444031560.959
Human
small molecule biosynthetic processGO:00442831570.957
Yeast
response to host defensesGO:005220020.957
negative regulation of ion transmembrane transportGO:0034766260.955
Human
negative regulation of potassium ion transmembrane transportGO:190138050.955
Human
negative regulation of cell growthGO:0030308830.955
negative regulation of potassium ion transportGO:004326760.954
Human
regulation of intracellular transportGO:00323861950.952
Human Yeast
negative regulation of pathway restricted smad protein phosphorylationGO:0060394110.952
ketone biosynthetic processGO:0042181170.949
Yeast
regulation of protein catabolic processGO:00421761550.947
Human Yeast
regulation of protein transportGO:00512232130.946
Human
response to external biotic stimulusGO:00432072610.944
Human
cellular potassium ion transportGO:0071804600.943
Human
regulation of nodal signaling pathway involved in determination of left right asymmetryGO:190014510.941
positive regulation of fatty acid metabolic processGO:0045923110.940
Yeast
cellular amine metabolic processGO:0044106410.937
lipid metabolic processGO:00066293810.932
Yeast
organic acid biosynthetic processGO:0016053970.931
Yeast
epithelial to mesenchymal transitionGO:0001837480.931
lateral mesoderm developmentGO:004836810.929
trna processingGO:0008033230.924
Yeast
mitochondrion organizationGO:00070051560.924
Yeast
inorganic cation transmembrane transportGO:00986621940.922
Human
regulation of nodal signaling pathway involved in determination of lateral mesoderm left right asymmetryGO:190017510.921
rna processingGO:00063962550.920
Yeast
cell developmentGO:00484683280.919
Human Fly
protein targetingGO:00066051870.919
Human
neurogenesisGO:00220081690.918
Human
endocardial cushion developmentGO:000319730.917
positive regulation of aldosterone metabolic processGO:003234620.916
regulation of wnt signaling pathwayGO:00301111230.915
negative regulation of transmembrane transportGO:0034763290.914
Human
cellular macromolecule catabolic processGO:00442653800.913
regulation of protein ubiquitinationGO:0031396950.911
response to sterolGO:0036314140.907
regulation of potassium ion transportGO:0043266240.906
Human
avoidance of host defensesGO:004441320.903
positive regulation of lipid biosynthetic processGO:0046889220.903
Yeast
regulation of stem cell differentiationGO:2000736560.902
cation transmembrane transportGO:00986552380.902
Human
modulation by virus of host morphology or physiologyGO:0019048100.902
regulation of cell morphogenesis involved in differentiationGO:0010769830.898
response to defenses of other organism involved in symbiotic interactionGO:005217320.896
establishment of protein localization to organelleGO:00725941720.891
Human
nodal signaling pathway involved in determination of left right asymmetryGO:003810710.887
cellular alcohol biosynthetic processGO:004410870.887
Yeast
response to hostGO:007513620.885
protein autoubiquitinationGO:0051865370.884
Human Yeast
positive regulation of epithelial to mesenchymal transitionGO:0010718220.883
mesenchymal cell differentiationGO:0048762520.876
negative regulation of ubiquitin protein transferase activityGO:005144480.875
regulation of alcohol biosynthetic processGO:1902930220.875
Yeast
blood vessel developmentGO:00015681720.874
regulation of smad protein import into nucleusGO:0060390100.869
positive regulation of cell adhesionGO:0045785840.869
single organism cell adhesionGO:00986021790.868
coenzyme metabolic processGO:0006732650.861
Yeast
positive regulation of canonical wnt signaling pathwayGO:0090263330.859
establishment of rna localizationGO:0051236390.851
Yeast
positive regulation of endocytosisGO:0045807420.851
Yeast
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090100410.845
positive regulation of mesoderm developmentGO:200038220.844
regulation of ligase activityGO:0051340290.843
positive regulation of wnt signaling pathwayGO:0030177540.842
protein localization to vacuoleGO:0072665110.842
Human
trna metabolic processGO:0006399350.839
Yeast
cellular component morphogenesisGO:00329893140.838
Yeast
rrna metabolic processGO:0016072400.838
Yeast
positive regulation of phosphatidylinositol 3 kinase signalingGO:0014068280.832
Human
positive regulation of osteoblast differentiationGO:0045669230.831
response to lipidGO:00339932060.824
negative regulation of smad protein complex assemblyGO:001099140.822
rna transportGO:0050658390.821
Yeast
negative regulation of defense responseGO:0031348470.812
Human
sodium ion transportGO:0006814610.812
Human
negative regulation of cell deathGO:00605483450.812
Human
hard palate developmentGO:006002210.811
mrna transportGO:0051028300.809
Yeast
positive regulation of developmental processGO:00510943140.808
regulation of proteolysisGO:00301622930.806
Yeast
regulation of smad protein complex assemblyGO:001099040.801
cellular protein catabolic processGO:00442572610.794
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathwayGO:0043162100.789
Human Yeast
single organism cellular localizationGO:19025803320.786
Human
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetryGO:190009410.786
positive regulation of mesenchymal cell proliferationGO:000205320.785
adherens junction organizationGO:0034332360.784
regulation of lipid metabolic processGO:0019216960.783
Yeast
positive regulation of peptidase activityGO:0010952880.783
positive regulation of aldosterone biosynthetic processGO:003234920.782
response to abiotic stimulusGO:00096283360.779
Human Yeast
positive regulation of intracellular protein transportGO:0090316760.778
positive regulation of transforming growth factor beta receptor signaling pathwayGO:0030511120.776
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulusGO:190152220.776
negative regulation of gliogenesisGO:001401430.775
cytoplasmic transportGO:00164823790.774
Human Yeast
cellular ketone metabolic processGO:0042180800.772
Yeast
membrane repolarizationGO:0086009230.770
Human
post embryonic developmentGO:000979120.766
ribosome biogenesisGO:0042254480.764
Yeast
positive regulation of lipid metabolic processGO:0045834500.762
Yeast
protein targeting to vacuoleGO:000662380.757
Human
regulation of receptor mediated endocytosisGO:0048259320.756
Yeast
negative regulation of cellular amine metabolic processGO:003323930.755
determination of left right asymmetry in lateral mesodermGO:000314010.754
urogenital system developmentGO:0001655650.752
stem cell divisionGO:001714520.749
ribonucleoprotein complex export from nucleusGO:007142640.748
Yeast
segmentationGO:003528240.747
vacuolar transportGO:0007034340.746
Human Yeast
proteasomal protein catabolic processGO:00104981760.743
Human Yeast
determination of bilateral symmetryGO:0009855150.733
response to cholesterolGO:0070723110.730
regulation of sequence specific dna binding transcription factor activityGO:00510902110.729
positive regulation of protein ubiquitinationGO:0031398530.727
regulation of mapk cascadeGO:00434082620.726
carboxylic acid biosynthetic processGO:0046394970.714
Yeast
inositol lipid mediated signalingGO:0048017550.714
Human
alcohol metabolic processGO:00060661140.710
Yeast
positive regulation of cell differentiationGO:00455972110.709
regulation of cytokine productionGO:00018172320.708
mesonephric tubule developmentGO:0072164140.708
ncrna processingGO:0034470830.706
Yeast
response to radiationGO:00093141510.705
Human Yeast
positive regulation of mapk cascadeGO:00434101900.705
response to fluid shear stressGO:0034405140.704
lipid biosynthetic processGO:00086101770.702
Yeast
neuron fate commitmentGO:004866320.698
adherens junction assemblyGO:0034333340.695
cofactor metabolic processGO:0051186870.692
Yeast
sterol biosynthetic processGO:0016126100.688
Yeast
negative regulation of transporter activityGO:0032410250.686
Human
positive regulation of transportGO:00510503360.686
Human Yeast
negative regulation of cell differentiationGO:00455961710.682
autophagyGO:0006914880.680
Yeast
ncrna metabolic processGO:00346601080.676
Yeast
fatty acid metabolic processGO:00066311150.674
Yeast
mrna export from nucleusGO:0006406290.674
Yeast
defense response to other organismGO:00985421290.672
Human
regulation of nodal signaling pathwayGO:190010710.671
mesenchyme developmentGO:0060485590.669
cell junction organizationGO:0034330790.667
organic hydroxy compound metabolic processGO:19016151470.661
Yeast
stem cell maintenanceGO:0019827190.661
negative regulation of ion transportGO:0043271390.657
Human
fatty acid biosynthetic processGO:0006633460.657
Yeast
regulation of lipid biosynthetic processGO:0046890470.655
Yeast
progesterone receptor signaling pathwayGO:005084730.645
Human
cell cell junction organizationGO:0045216690.641
cell morphogenesis involved in differentiationGO:00009041440.640
protein targeting to lysosomeGO:000662280.638
Human
positive regulation of phosphorylationGO:00423273940.634
regulation of cell developmentGO:00602841610.632
cofactor biosynthetic processGO:0051188310.629
Yeast
regulation of protein localization to cell surfaceGO:2000008150.627
Human
regulation of osteoblast differentiationGO:0045667380.627
regulation of cell differentiationGO:00455953930.623
wnt signaling pathwayGO:00160551560.622
positive regulation of cell cell adhesionGO:0022409220.620
dorsal ventral pattern formationGO:0009953150.619
regulation of multi organism processGO:00439001570.618
Human Yeast
cell projection organizationGO:00300302520.617
Human Yeast
mesonephros developmentGO:0001823170.617
regulation of endopeptidase activityGO:00525481700.615
regulation of fatty acid metabolic processGO:0019217240.615
Yeast
regulation of transcription factor import into nucleusGO:0042990390.612
negative regulation of programmed cell deathGO:00430693210.605
Human
regulation of cell growthGO:00015581350.602
positive regulation of smad protein import into nucleusGO:006039180.598
rna localizationGO:0006403410.598
Yeast
response to organic cyclic compoundGO:00140702040.596
viral processGO:00160321460.596
Human
ubiquinone metabolic processGO:000674350.592
Yeast
mesoderm developmentGO:0007498140.589
canonical wnt signaling pathwayGO:00600701160.582
regulation of cell adhesionGO:00301551660.581
intracellular receptor signaling pathwayGO:00305221040.580
Human
adaptive immune responseGO:0002250490.580
cell proliferation involved in heart valve developmentGO:200079310.579
intracellular steroid hormone receptor signaling pathwayGO:0030518610.576
Human
regulation of canonical wnt signaling pathwayGO:0060828880.572
regulation of jnk cascadeGO:0046328730.570
regulation of cell projection organizationGO:00313441070.568
Yeast
ubiquinone biosynthetic processGO:000674450.565
Yeast
positive regulation of programmed cell deathGO:00430682490.564
regulation of cell cell adhesionGO:0022407570.563
regulation of transporter activityGO:0032409820.559
Human
tube developmentGO:00352951250.559
Fly
regulation of stress activated mapk cascadeGO:0032872840.555
positive regulation of protein transportGO:00512221350.555
establishment of protein localization to vacuoleGO:007266680.550
Human
receptor metabolic processGO:0043112810.550
Human
regulation of protein localizationGO:00328802960.547
Human Yeast
response to light stimulusGO:0009416870.542
Human Yeast
regulation of neuron differentiationGO:0045664700.541
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787370.539
Human Yeast Fly
heart contractionGO:0060047620.530
positive regulation of pathway restricted smad protein phosphorylationGO:0010862220.527
negative regulation of cell proliferationGO:00082852280.527
regulation of transmembrane transporter activityGO:0022898740.525
Human
specification of symmetryGO:0009799160.522
negative regulation of protein ubiquitinationGO:0031397350.517
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.515
Yeast
positive regulation of protein phosphorylationGO:00019343130.514
renal system developmentGO:0072001630.511
regulation of phosphatidylinositol 3 kinase signalingGO:0014066350.508
Human
actin cytoskeleton organizationGO:00300362070.500
Yeast
endocardium developmentGO:000315720.497
regulation of intracellular protein transportGO:00331571230.495
negative regulation of cellular amino acid metabolic processGO:004576320.493
intracellular protein transportGO:00068862700.493
Human
monocarboxylic acid metabolic processGO:00327871850.489
Yeast
fat cell differentiationGO:0045444320.488
regulation of vesicle mediated transportGO:00606271300.487
Yeast
somitogenesisGO:000175620.487
regulation of defense response to virusGO:0050688330.486
Human
positive regulation of cell morphogenesis involved in differentiationGO:0010770500.485
protein monoubiquitinationGO:0006513390.483
Yeast
negative regulation of ligase activityGO:005135280.481
positive regulation of receptor mediated endocytosisGO:0048260210.481
Yeast
positive regulation of jun kinase activityGO:0043507230.479
negative regulation of immune effector processGO:0002698380.478
Human
ribonucleoprotein complex biogenesisGO:00226131160.476
Yeast
neuron developmentGO:00486661130.475
Human
negative regulation of transcription by competitive promoter bindingGO:001094480.474
determination of adult lifespanGO:000834020.474
regulation of membrane depolarizationGO:0003254190.473
Human
positive regulation of cell developmentGO:0010720920.470
regulation of nervous system developmentGO:0051960880.465
neural tube formationGO:000184130.465
negative regulation of muscle organ developmentGO:0048635120.465
positive regulation of protein import into nucleusGO:0042307460.464
epithelium developmentGO:00604292270.463
defense response to virusGO:0051607710.461
Human
cellular amino acid metabolic processGO:00065201160.459
digestive tract developmentGO:0048565750.458
Fly
ribosome localizationGO:003375040.457
Yeast
regulation of homeostatic processGO:00328441210.449
Human
cellular protein complex localizationGO:003462980.447
nodal signaling pathwayGO:003809250.443
defense responseGO:00069523150.440
Human
regulation of mesoderm developmentGO:200038040.439
positive regulation of protein kinase activityGO:00458601900.438
nervous system developmentGO:00073992930.436
Human
transcription factor import into nucleusGO:0042991400.436
regulation of transmembrane transportGO:00347621390.435
Human
regulation of cysteine type endopeptidase activityGO:20001161270.435
regulation of ubiquitin protein transferase activityGO:0051438280.432
nitrogen compound transportGO:00717051910.430
Yeast
regulation of steroid metabolic processGO:0019218320.430
Yeast
positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left right asymmetryGO:190022410.428
cellular response to light stimulusGO:0071482340.428
Human Yeast
transforming growth factor beta productionGO:0071604140.425
single organism nuclear importGO:19025931040.423
alcohol biosynthetic processGO:0046165520.419
Yeast
positive regulation of hydrolase activityGO:00513453310.415
circulatory system developmentGO:00723592620.414
cell morphogenesis involved in neuron differentiationGO:0048667440.414
morphogenesis of an epitheliumGO:0002009600.413
axis specificationGO:0009798120.412
response to decreased oxygen levelsGO:0036293960.412
regulation of nucleobase containing compound transportGO:003223970.410
Yeast
artery morphogenesisGO:004884470.408
regulation of protein import into nucleusGO:0042306780.407
ion homeostasisGO:00508012300.402
Human
cell substrate adhesionGO:00315891320.402
generation of neuronsGO:00486991520.399
Human
regulation of defense responseGO:00313471540.395
Human
regulation of catenin import into nucleusGO:0035412180.384
peptidyl threonine modificationGO:0018210450.380
rna export from nucleusGO:0006405330.378
Yeast
response to bmpGO:007177280.374
positive regulation of stress activated mapk cascadeGO:0032874600.369
negative regulation of cellular component organizationGO:00511292350.367
catenin import into nucleusGO:0035411180.365
regulation of peptidyl serine phosphorylationGO:0033135500.362
positive regulation of cellular component organizationGO:00511303760.359
Yeast
regulation of sodium ion transmembrane transporter activityGO:2000649170.357
Human
establishment of organelle localizationGO:0051656590.357
Yeast
nuclear exportGO:0051168690.356
Human Yeast
negative regulation of apoptotic processGO:00430663160.355
Human
cell projection morphogenesisGO:00488581290.352
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.349
positive regulation of hormone biosynthetic processGO:004688640.346
positive regulation of cell deathGO:00109422630.345
cardiac septum developmentGO:0003279130.343
regulation of muscle system processGO:0090257530.341
negative regulation of phosphorylationGO:00423261740.337
negative regulation of immune system processGO:00026831360.336
Human
negative regulation of defense response to virusGO:0050687100.332
Human
positive regulation of protein localization to nucleusGO:1900182480.331
smad protein signal transductionGO:0060395100.331
amine metabolic processGO:0009308440.330
cellular lipid metabolic processGO:00442553030.330
Yeast
osteoblast differentiationGO:0001649920.329
modification of morphology or physiology of other organismGO:0035821430.328
negative regulation of phosphate metabolic processGO:00459362670.327
protein export from nucleusGO:0006611290.325
Human
regulation of protein localization to nucleusGO:1900180850.325
zymogen activationGO:0031638700.325
negative regulation of protein transportGO:0051224750.325
Human
vesicle mediated transportGO:00161923710.323
Human Yeast
negative regulation of chorionic trophoblast cell proliferationGO:190138320.322
regulation of system processGO:00440571010.320
monovalent inorganic cation transportGO:00156721280.318
Human
biological adhesionGO:00226103310.318
regulation of sodium ion transportGO:0002028240.316
Human
late endosome to vacuole transportGO:004532420.316
Yeast
regulation of ossificationGO:0030278580.314
cell part morphogenesisGO:00329901370.314
negative regulation of developmental processGO:00510932470.314
regulation of cellular component biogenesisGO:00440872810.311
Yeast
muscle organ developmentGO:0007517560.311
transforming growth factor beta2 productionGO:003290660.310
nucleobase containing compound transportGO:0015931510.304
Yeast
cell adhesionGO:00071553250.304
cytokine productionGO:00018162470.302
extrinsic apoptotic signaling pathwayGO:00971911190.301
anatomical structure formation involved in morphogenesisGO:00486462840.298
Yeast Fly
growthGO:00400072020.295
Fly
kidney developmentGO:0001822530.294
cardiac atrium morphogenesisGO:000320970.291
regulation of mineralocorticoid secretionGO:200085510.291
regulation of response to biotic stimulusGO:0002831550.286
Human
organelle localizationGO:0051640840.284
Yeast
regulation of transferase activityGO:00513383550.282
regulation of ion transmembrane transportGO:00347651320.278
Human
endocrine hormone secretionGO:0060986130.278
negative regulation of growthGO:0045926970.277
cardiovascular system developmentGO:00723582620.272
regulation of actin filament based processGO:00329701410.272
Yeast
negative regulation of multicellular organismal processGO:00512413170.271
regulation of cellular amine metabolic processGO:0033238110.270
sterol metabolic processGO:0016125280.268
Yeast
regulation of protein stabilityGO:0031647870.266
regulation of cell morphogenesisGO:00226041530.265
Yeast
modification of morphology or physiology of other organism involved in symbiotic interactionGO:0051817380.265
regulation of sodium ion transmembrane transportGO:1902305230.264
Human
otic vesicle developmentGO:007159910.261
cellular response to radiationGO:0071478650.260
Human Yeast
mesonephric epithelium developmentGO:0072163140.259
endodermal cell fate specificationGO:000171440.259
positive regulation of activin receptor signaling pathwayGO:003292760.257
embryo developmentGO:00097901230.255
Fly
positive regulation of jnk cascadeGO:0046330520.252
immune effector processGO:00022521590.251
Human
smad protein import into nucleusGO:0007184130.249
phosphatidylinositol mediated signalingGO:0048015550.248
Human
maintenance of locationGO:00512351120.247
protein stabilizationGO:0050821640.246
regulation of cellular component sizeGO:0032535820.243
Yeast
glucocorticoid receptor signaling pathwayGO:004292150.242
Human
regulation of immune effector processGO:0002697910.240
Human
cell morphogenesisGO:00009022960.239
Yeast
positive regulation of transcription factor import into nucleusGO:0042993250.238
endocrine system developmentGO:0035270260.238
atrioventricular valve developmentGO:000317130.237
embryonic heart tube morphogenesisGO:000314380.235

SMURF2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
bone diseaseDOID:0080001880.695
musculoskeletal system diseaseDOID:172230.695
connective tissue diseaseDOID:651090.695
heart diseaseDOID:114680.335
cardiovascular system diseaseDOID:12871060.335
cancerDOID:1621670.289
disease of cellular proliferationDOID:145661740.289