Homo sapiens

44 known processes

CTSL1

cathepsin L1

(Aliases: CTSL,CATL,MEP,FLJ31037)

CTSL1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of cell deathGO:00605483450.223
lipid metabolic processGO:00066293810.220
chemical homeostasisGO:00488783060.190
cellular amino acid metabolic processGO:00065201160.159
cytokine productionGO:00018162470.150
lipid localizationGO:00108761060.120
determination of adult lifespanGO:000834020.119
oxidation reduction processGO:00551143960.107
multicellular organismal agingGO:001025930.104
ion homeostasisGO:00508012300.101
response to cytokineGO:00340972320.100
cellular lipid metabolic processGO:00442553030.098
cellular amine metabolic processGO:0044106410.095
anatomical structure formation involved in morphogenesisGO:00486462840.094
cellular cation homeostasisGO:00300031630.094
cellular ion homeostasisGO:00068731680.093
positive regulation of cellular amine metabolic processGO:003324070.092
post embryonic developmentGO:000979120.088
glial cell migrationGO:000834740.086
negative regulation of programmed cell deathGO:00430693210.085
response to organic cyclic compoundGO:00140702040.081
regulation of secretionGO:00510461940.080
single organism carbohydrate metabolic processGO:00447231930.079
cellular lipid catabolic processGO:0044242650.078
apoptotic signaling pathwayGO:00971902680.075
lipid catabolic processGO:0016042840.072
response to nitrogen compoundGO:19016981840.070
carbohydrate metabolic processGO:00059752070.070
cellular ketone metabolic processGO:0042180800.069
circulatory system developmentGO:00723592620.068
regulation of cell motilityGO:20001452990.066
regulation of cellular ketone metabolic processGO:0010565500.066
response to oxygen containing compoundGO:19017003690.066
immune responseGO:00069553070.064
response to oxidative stressGO:00069791210.063
metal ion homeostasisGO:00550651690.063
response to abiotic stimulusGO:00096283360.062
amine metabolic processGO:0009308440.062
negative regulation of apoptotic processGO:00430663160.061
cation homeostasisGO:00550801890.058
signal transduction by phosphorylationGO:00230142970.057
negative regulation of catalytic activityGO:00430863350.056
locomotory behaviorGO:000762610.056
regulation of anatomical structure morphogenesisGO:00226032860.056
negative regulation of cellular protein metabolic processGO:00322693530.054
positive regulation of transportGO:00510503360.054
regulation of cellular amino acid metabolic processGO:000652160.054
sulfur compound metabolic processGO:00067901010.053
response to thyroid hormoneGO:009706690.052
cellular response to oxygen containing compoundGO:19017012760.052
positive regulation of phosphorylationGO:00423273940.052
dicarboxylic acid biosynthetic processGO:004365040.051
negative regulation of cell migrationGO:00303361020.051
regulation of apoptotic signaling pathwayGO:20012331750.049
transmembrane transportGO:00550853990.049
response to inorganic substanceGO:00100351270.049
female gamete generationGO:000729220.049
lipid biosynthetic processGO:00086101770.049
regulation of oxidative stress induced cell deathGO:1903201240.049
response to organonitrogen compoundGO:00102431560.048
membrane lipid metabolic processGO:0006643530.048
calcium ion homeostasisGO:00550741220.047
cellular homeostasisGO:00197251960.046
vesicle mediated transportGO:00161923710.046
small molecule biosynthetic processGO:00442831570.046
vasculature developmentGO:00019441810.044
cell type specific apoptotic processGO:00972851250.043
cellular chemical homeostasisGO:00550821800.043
epithelial cell differentiationGO:00308551410.042
cellular macromolecule catabolic processGO:00442653800.042
regulation of cellular response to stressGO:00801352440.042
secretionGO:00469032540.042
regulation of locomotionGO:00400123290.042
negative regulation of hydrolase activityGO:00513461820.042
cellular metal ion homeostasisGO:00068751460.041
monocarboxylic acid metabolic processGO:00327871850.041
regulation of ion transportGO:00432691890.041
cell death in response to oxidative stressGO:0036473290.040
blood vessel morphogenesisGO:00485141620.040
cellular response to endogenous stimulusGO:00714953360.040
negative regulation of cell proliferationGO:00082852280.039
oogenesisGO:004847720.039
defense responseGO:00069523150.039
organic hydroxy compound transportGO:0015850630.038
response to tumor necrosis factorGO:0034612760.037
maintenance of locationGO:00512351120.037
cellular protein catabolic processGO:00442572610.037
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237520.037
cation transportGO:00068123310.036
cellular response to thyroid hormone stimulusGO:009706790.036
innate immune responseGO:00450871780.036
cell adhesionGO:00071553250.036
matingGO:000761810.034
single organismal cell cell adhesionGO:00163371480.034
cellular response to oxidative stressGO:0034599850.034
alcohol metabolic processGO:00060661140.033
regulation of vasculature developmentGO:1901342970.033
regulation of cell adhesionGO:00301551660.033
negative regulation of cell motilityGO:20001461040.033
single organism membrane organizationGO:00448022680.033
regulation of secretion by cellGO:19035301770.033
positive regulation of protein kinase activityGO:00458601900.033
epithelium developmentGO:00604292270.033
mapk cascadeGO:00001652880.032
negative regulation of protein metabolic processGO:00512483910.032
regulation of mapk cascadeGO:00434082620.032
cytoplasmic transportGO:00164823790.032
cellular divalent inorganic cation homeostasisGO:00725031280.032
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.031
organonitrogen compound biosynthetic processGO:19015662000.031
response to bacteriumGO:00096171440.031
system processGO:00030083490.031
regulation of cellular component movementGO:00512703340.031
regulation of cell migrationGO:00303342890.031
response to biotic stimulusGO:00096072760.031
metal ion transportGO:00300012720.031
vacuole organizationGO:0007033440.030
negative regulation of multicellular organismal processGO:00512413170.030
protein maturationGO:00516042330.030
response to reactive oxygen speciesGO:0000302610.030
immune system developmentGO:00025201950.030
cardiovascular system developmentGO:00723582620.030
negative regulation of developmental processGO:00510932470.029
sphingolipid metabolic processGO:0006665380.029
regulation of cell differentiationGO:00455953930.029
neurological system processGO:00508771630.029
positive regulation of cellular component organizationGO:00511303760.028
regulation of cellular amine metabolic processGO:0033238110.028
i kappab kinase nf kappab signalingGO:00072491660.028
myeloid cell differentiationGO:00300991170.028
negative regulation of apoptotic signaling pathwayGO:2001234970.028
regulation of transferase activityGO:00513383550.028
organophosphate biosynthetic processGO:00904071630.027
regulation of establishment of protein localizationGO:00702012420.027
angiogenesisGO:00015251470.027
negative regulation of protein processingGO:00109551420.027
regulation of proteolysisGO:00301622930.027
positive regulation of cellular amino acid metabolic processGO:004576430.027
regenerationGO:003109940.027
single organism reproductive processGO:0044702980.027
proteolysis involved in cellular protein catabolic processGO:00516032440.026
secretion by cellGO:00329402260.026
cellular amide metabolic processGO:0043603690.026
biological adhesionGO:00226103310.026
regulation of protein maturationGO:19033171500.026
sequestering of metal ionGO:0051238240.026
monovalent inorganic cation transportGO:00156721280.026
growthGO:00400072020.026
carboxylic acid biosynthetic processGO:0046394970.026
regulation of transmembrane transportGO:00347621390.026
response to hormoneGO:00097251750.026
epithelial cell proliferationGO:00506731280.026
negative regulation of locomotionGO:00400131180.025
positive regulation of immune system processGO:00026842830.025
regulation of protein transportGO:00512232130.025
receptor metabolic processGO:0043112810.025
glutathione metabolic processGO:0006749200.025
endomembrane system organizationGO:00102561960.025
positive regulation of secretionGO:00510471160.025
phospholipid metabolic processGO:0006644990.025
regulation of vesicle mediated transportGO:00606271300.025
divalent inorganic cation homeostasisGO:00725071360.025
cellular component morphogenesisGO:00329893140.024
response to metal ionGO:0010038840.024
organic hydroxy compound metabolic processGO:19016151470.024
positive regulation of cell motilityGO:20001471770.024
g protein coupled receptor signaling pathwayGO:00071862070.024
positive regulation of protein phosphorylationGO:00019343130.024
hematopoietic or lymphoid organ developmentGO:00485341860.024
positive regulation of hydrolase activityGO:00513453310.024
regulation of lipid metabolic processGO:0019216960.024
negative regulation of oxidative stress induced cell deathGO:1903202170.024
negative regulation of cellular component movementGO:00512711060.023
regulation of cytokine productionGO:00018172320.023
regulation of protein processingGO:00706131500.023
cellular response to organic cyclic compoundGO:00714071270.023
negative regulation of immune system processGO:00026831360.023
ribonucleotide catabolic processGO:00092614050.023
positive regulation of transferase activityGO:00513472270.023
response to other organismGO:00517072610.022
regulation of cellular response to oxidative stressGO:1900407260.022
hemopoiesisGO:00300971800.022
response to lipidGO:00339932060.022
regulation of ion transmembrane transportGO:00347651320.022
hindbrain developmentGO:003090230.022
inorganic cation transmembrane transportGO:00986621940.022
regulation of sequence specific dna binding transcription factor activityGO:00510902110.022
lipid transportGO:0006869900.022
organic acid biosynthetic processGO:0016053970.022
liposaccharide metabolic processGO:1903509270.022
response to external biotic stimulusGO:00432072610.022
regulation of purine nucleotide metabolic processGO:19005422640.022
protein processingGO:00164852260.022
cellular response to lipidGO:00713961270.022
response to activityGO:001482300.022
response to extracellular stimulusGO:0009991850.022
protein homooligomerizationGO:00512601000.022
negative regulation of proteolysisGO:00458611320.022
negative regulation of phosphorus metabolic processGO:00105632670.022
response to nutrient levelsGO:0031667810.022
regulation of endopeptidase activityGO:00525481700.021
cation transmembrane transportGO:00986552380.021
cellular response to external stimulusGO:00714961110.021
protein oligomerizationGO:00512591730.021
blood vessel developmentGO:00015681720.021
regulation of protein localizationGO:00328802960.021
purine containing compound catabolic processGO:00725234110.021
negative regulation of endopeptidase activityGO:0010951840.021
intracellular protein transportGO:00068862700.020
regulation of response to oxidative stressGO:1902882260.020
behaviorGO:00076101120.020
inorganic ion transmembrane transportGO:00986602310.020
regulation of hormone levelsGO:00108171250.020
neurogenesisGO:00220081690.020
cofactor metabolic processGO:0051186870.020
nucleoside triphosphate catabolic processGO:00091433940.020
cyclic nucleotide metabolic processGO:0009187820.020
transmission of nerve impulseGO:0019226110.020
positive regulation of cell proliferationGO:00082843010.020
ion transmembrane transportGO:00342203380.020
cellular response to hormone stimulusGO:00328701250.019
carbohydrate derivative biosynthetic processGO:19011372070.019
reactive nitrogen species metabolic processGO:200105730.019
wound healingGO:00420601150.019
cellular modified amino acid metabolic processGO:0006575640.019
positive regulation of immune responseGO:00507781590.019
positive regulation of macrophage chemotaxisGO:001075930.019
fibroblast proliferationGO:0048144330.019
vasodilationGO:004231140.019
response to hydrogen peroxideGO:0042542400.019
positive regulation of cell deathGO:00109422630.019
glycolipid metabolic processGO:0006664270.019
purine ribonucleoside triphosphate catabolic processGO:00092073910.019
regulation of defense responseGO:00313471540.019
enzyme linked receptor protein signaling pathwayGO:00071673030.019
exocytosisGO:0006887710.019
cellular response to hydrogen peroxideGO:0070301370.019
regulation of cell cell adhesionGO:0022407570.019
regulation of angiogenesisGO:0045765920.018
negative regulation of intracellular signal transductionGO:19025321830.018
cell activationGO:00017752130.018
reactive oxygen species biosynthetic processGO:190340940.018
taxisGO:00423301570.018
intrinsic apoptotic signaling pathwayGO:00971931270.018
negative regulation of protein maturationGO:19033181420.018
negative regulation of phosphate metabolic processGO:00459362670.018
regulation of neuron deathGO:1901214560.018
regulation of response to woundingGO:19030341010.018
regulation of i kappab kinase nf kappab signalingGO:00431221620.018
regulation of peptidase activityGO:00525471800.018
protein localization to membraneGO:00726571600.018
positive regulation of mapk cascadeGO:00434101900.018
prostate gland developmentGO:003085030.018
positive regulation of cytokine productionGO:00018191670.018
tissue migrationGO:00901301190.018
rho protein signal transductionGO:0007266260.017
cellular response to growth factor stimulusGO:00713631970.017
regulation of response to external stimulusGO:00321012220.017
ribonucleoside triphosphate metabolic processGO:00091994120.017
steroid metabolic processGO:0008202940.017
epithelium migrationGO:00901321190.017
sensory perceptionGO:00076001030.017
fatty acid metabolic processGO:00066311150.017
inner ear morphogenesisGO:004247240.017
regulation of immune responseGO:00507762010.017
extrinsic apoptotic signaling pathwayGO:00971911190.017
nervous system developmentGO:00073992930.017
multicellular organismal signalingGO:0035637340.017
positive regulation of developmental processGO:00510943140.017
protein localization to organelleGO:00333652800.017
protein secretionGO:0009306980.016
positive regulation of cell migrationGO:00303351720.016
protein catabolic processGO:00301633250.016
neuronal action potentialGO:001922890.016
multicellular organismal macromolecule metabolic processGO:0044259290.016
positive regulation of aldosterone metabolic processGO:003234620.016
transition metal ion homeostasisGO:0055076310.016
purine ribonucleotide catabolic processGO:00091544040.016
ras protein signal transductionGO:0007265730.016
cell projection organizationGO:00300302520.016
regulation of cellular response to growth factor stimulusGO:0090287760.016
circulatory system processGO:00030131130.016
glycerolipid metabolic processGO:00464861070.016
agingGO:0007568660.016
cellular calcium ion homeostasisGO:00068741170.016
regulation of macrophage chemotaxisGO:001075840.016
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.016
regulation of protein kinase activityGO:00458592890.016
positive regulation of cellular catabolic processGO:00313312840.016
cellular response to nutrient levelsGO:0031669690.016
reproductive processGO:00224141060.016
organophosphate catabolic processGO:00464344300.015
negative regulation of cellular response to oxidative stressGO:1900408180.015
cell morphogenesisGO:00009022960.015
negative regulation of peptidase activityGO:0010466910.015
regulation of growthGO:00400081650.015
purine nucleoside triphosphate catabolic processGO:00091463920.015
positive regulation of apoptotic processGO:00430652460.015
positive regulation of cell differentiationGO:00455972110.015
peptidyl tyrosine phosphorylationGO:00181081700.015
single organism cellular localizationGO:19025803320.015
response to radiationGO:00093141510.015
nucleotide catabolic processGO:00091664080.015
cellular response to reactive oxygen speciesGO:0034614500.015
negative regulation of protein modification processGO:00314002000.015
purine ribonucleoside triphosphate metabolic processGO:00092054110.015
positive regulation of kinase activityGO:00336742040.015
regulation of reactive oxygen species metabolic processGO:2000377410.015
positive regulation of aldosterone biosynthetic processGO:003234920.015
embryo developmentGO:00097901230.015
positive regulation of catabolic processGO:00098963100.015
response to growth factorGO:00708482050.014
positive regulation of locomotionGO:00400171860.014
spermatid differentiationGO:004851540.014
detection of stimulusGO:0051606850.014
sequestering of calcium ionGO:0051208170.014
chemotaxisGO:00069351570.014
small molecule catabolic processGO:0044282920.014
response to axon injuryGO:004867810.014
peptidyl tyrosine modificationGO:00182121700.014
camp metabolic processGO:0046058610.014
negative regulation of fibroblast growth factor receptor signaling pathwayGO:004003720.014
retina vasculature morphogenesis in camera type eyeGO:006129930.014
adult locomotory behaviorGO:000834410.014
cell growthGO:00160491600.014
activation of immune responseGO:00022531140.014
purine nucleoside triphosphate metabolic processGO:00091444120.014
response to xenobiotic stimulusGO:0009410300.014
response to increased oxygen levelsGO:003629640.014
negative regulation of vasculature developmentGO:1901343430.014
regulation of erk1 and erk2 cascadeGO:0070372990.014
regulation of intracellular transportGO:00323861950.013
collagen catabolic processGO:0030574100.013
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.013
regulation of nucleotide metabolic processGO:00061402690.013
negative regulation of cellular amine metabolic processGO:003323930.013
negative regulation of blood vessel morphogenesisGO:2000181410.013
regulation of protein catabolic processGO:00421761550.013
cellular response to dna damage stimulusGO:00069743790.013
purine ribonucleoside metabolic processGO:00461284370.013
ribonucleoside catabolic processGO:00424544060.013
erk1 and erk2 cascadeGO:00703711040.013
gland developmentGO:0048732480.013
response to acid chemicalGO:0001101660.013
regulation of kinase activityGO:00435493140.013
response to woundingGO:00096111680.013
nucleotide biosynthetic processGO:00091651090.013
ceramide metabolic processGO:0006672250.013
cholesterol transportGO:0030301390.013
wnt signaling pathwayGO:00160551560.013
positive regulation of synaptic transmissionGO:005080640.013
nuclear transportGO:00511691790.013
anion transportGO:00068201610.013
nucleoside catabolic processGO:00091644080.013
neuron deathGO:0070997650.013
organic anion transportGO:00157111030.013
intrinsic apoptotic signaling pathway in response to oxidative stressGO:0008631210.012
regulation of metal ion transportGO:00109591200.012
regulation of protein secretionGO:0050708860.012
regulation of cytoplasmic transportGO:19036491490.012
establishment of protein localization to organelleGO:00725941720.012
negative regulation of transportGO:00510511760.012
regulation of reactive oxygen species biosynthetic processGO:190342630.012
segmentationGO:003528240.012
negative regulation of response to oxidative stressGO:1902883180.012
positive regulation of organelle organizationGO:00106381950.012
developmental programmed cell deathGO:001062330.012
membrane organizationGO:00610242920.012
endocytosisGO:00068971590.012
aromatic amino acid family metabolic processGO:000907230.012
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.012
lytic vacuole organizationGO:0080171240.012
leukocyte differentiationGO:0002521980.012
cell developmentGO:00484683280.012
generation of neuronsGO:00486991520.012
reactive oxygen species metabolic processGO:0072593750.012
positive regulation of secretion by cellGO:19035321080.012
aminoglycan metabolic processGO:0006022390.012
response to starvationGO:0042594590.012
positive regulation of purine nucleotide metabolic processGO:19005442270.012
regulation of epithelial cell proliferationGO:00506781130.012
action potentialGO:0001508340.012
single organism carbohydrate catabolic processGO:0044724330.012
methylationGO:00322591060.012
alpha amino acid metabolic processGO:1901605720.012
spermatid developmentGO:000728640.012
vesicle organizationGO:0016050620.012
tissue regenerationGO:004224630.012
response to fungusGO:000962040.012
cellular response to biotic stimulusGO:0071216710.012
regulation of cell morphogenesisGO:00226041530.011
negative regulation of cell differentiationGO:00455961710.011
cellular macromolecular complex assemblyGO:00346223240.011
ameboidal type cell migrationGO:00016671350.011
posttranscriptional regulation of gene expressionGO:00106082130.011
glycosyl compound catabolic processGO:19016584130.011
immune effector processGO:00022521590.011
cellular biogenic amine metabolic processGO:0006576340.011
response to oxygen levelsGO:00704821000.011
cytokine mediated signaling pathwayGO:00192211090.011
response to alcoholGO:0097305640.011
protein targetingGO:00066051870.011
protein tetramerizationGO:0051262470.011
cellular response to organonitrogen compoundGO:00714171240.011
negative regulation of neuron deathGO:1901215320.011
nucleoside triphosphate metabolic processGO:00091414220.011
positive regulation of cell adhesionGO:0045785840.011
response to transition metal nanoparticleGO:1990267290.011
blastoderm segmentationGO:000735020.011
neurotransmitter secretionGO:000726940.011
cellular response to extracellular stimulusGO:0031668720.011
regulation of cyclic nucleotide metabolic processGO:0030799630.011
negative regulation of cellular component organizationGO:00511292350.011
cellular response to starvationGO:0009267580.011
nucleoside phosphate catabolic processGO:19012924120.011
negative regulation of cellular amino acid metabolic processGO:004576320.011
positive regulation of cellular component biogenesisGO:00440891580.011
sodium ion transmembrane transportGO:0035725590.011
smooth muscle cell proliferationGO:0048659280.011
response to hyperoxiaGO:005509340.011
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.011
monosaccharide metabolic processGO:0005996740.011
cellular response to abiotic stimulusGO:00712141170.011
regulation of lipid biosynthetic processGO:0046890470.011
gtp catabolic processGO:00061842370.011
regulation of cell growthGO:00015581350.011
response to molecule of bacterial originGO:0002237820.010
neuron apoptotic processGO:0051402390.010
regulation of integrin mediated signaling pathwayGO:200104430.010
regulation of lipase activityGO:0060191370.010
regulation of endocytosisGO:0030100720.010
immune response regulating signaling pathwayGO:0002764970.010
small gtpase mediated signal transductionGO:0007264780.010
receptor mediated endocytosisGO:0006898840.010
nucleoside phosphate biosynthetic processGO:19012931090.010
purine ribonucleoside catabolic processGO:00461303980.010
mitotic cell cycleGO:00002783260.010
ribonucleoside triphosphate catabolic processGO:00092033910.010
glycosaminoglycan metabolic processGO:0030203350.010
t cell differentiation in thymusGO:003307740.010
positive regulation of programmed cell deathGO:00430682490.010
positive regulation of proteolysisGO:00458621420.010
peptide metabolic processGO:0006518510.010
membrane protein proteolysisGO:0033619380.010
phospholipid biosynthetic processGO:0008654440.010
generation of precursor metabolites and energyGO:0006091680.010
regulation of intracellular protein transportGO:00331571230.010
positive regulation of hormone biosynthetic processGO:004688640.010
nitrogen compound transportGO:00717051910.010
rubidium ion transportGO:003582640.010
macromolecule methylationGO:0043414970.010
positive regulation of protein transportGO:00512221350.010
response to interferon gammaGO:0034341390.010
positive regulation of transmembrane transportGO:0034764410.010
plasma membrane organizationGO:00070091150.010
positive regulation of cellular component movementGO:00512721810.010
response to decreased oxygen levelsGO:0036293960.010

CTSL1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:6552420.398
disease of metabolismDOID:00146672950.398
lysosomal storage diseaseDOID:3211470.398
nervous system diseaseDOID:8634310.268
central nervous system diseaseDOID:3311860.268
lipid storage diseaseDOID:9455280.069
brain diseaseDOID:936730.058
cerebral degenerationDOID:1443160.058
sensory system diseaseDOID:00501552030.031
eye and adnexa diseaseDOID:14921500.017
sphingolipidosisDOID:1927140.016
immune system diseaseDOID:29141550.015
eye diseaseDOID:56141490.014
disease of cellular proliferationDOID:145661740.014
neurodegenerative diseaseDOID:12891020.013
cancerDOID:1621670.012
retinal diseaseDOID:56791180.012
musculoskeletal system diseaseDOID:172230.012
organ system cancerDOID:00506861640.011