Homo sapiens

67 known processes

ZHX2

zinc fingers and homeoboxes 2

(Aliases: RAF,AFR1,KIAA0854)

ZHX2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cell differentiationGO:00455953930.123
Human Mouse
positive regulation of developmental processGO:00510943140.123
Human
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.102
associative learningGO:000830610.091
positive regulation of catabolic processGO:00098963100.079
cell morphogenesisGO:00009022960.077
enzyme linked receptor protein signaling pathwayGO:00071673030.059
memoryGO:000761330.058
cell fate determinationGO:000170930.055
system processGO:00030083490.054
post embryonic developmentGO:000979120.051
midgut developmentGO:000749410.047
negative regulation of cell proliferationGO:00082852280.046
long term memoryGO:000761620.046
canonical wnt signaling pathway involved in cardiac muscle cell fate commitmentGO:006131730.045
determination of adult lifespanGO:000834020.045
neurological system processGO:00508771630.045
generation of neuronsGO:00486991520.045
Mouse
cellular response to dna damage stimulusGO:00069743790.044
locomotory behaviorGO:000762610.043
female gamete generationGO:000729220.042
tube developmentGO:00352951250.041
response to abiotic stimulusGO:00096283360.041
cellular component morphogenesisGO:00329893140.041
mitotic cell cycleGO:00002783260.039
cell developmentGO:00484683280.039
Mouse
nervous system developmentGO:00073992930.039
Mouse
multicellular organismal agingGO:001025930.039
negative regulation of apoptotic processGO:00430663160.038
muscle cell fate commitmentGO:004269340.038
growthGO:00400072020.036
oogenesisGO:004847720.036
vesicle mediated transportGO:00161923710.036
blastoderm segmentationGO:000735020.035
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.034
regulation of cell cycle processGO:00105642660.034
actin filament based processGO:00300292240.034
ectoderm developmentGO:000739830.033
signal transduction by phosphorylationGO:00230142970.033
purine nucleoside triphosphate metabolic processGO:00091444120.033
negative regulation of cellular protein metabolic processGO:00322693530.032
regulation of cell cycleGO:00517263930.032
cell projection organizationGO:00300302520.032
cytoplasmic transportGO:00164823790.032
nuclear transportGO:00511691790.031
circulatory system developmentGO:00723592620.031
protein localization to organelleGO:00333652800.030
small gtpase mediated signal transductionGO:0007264780.030
regulation of cellular component biogenesisGO:00440872810.030
adult locomotory behaviorGO:000834410.030
covalent chromatin modificationGO:00165692540.029
negative regulation of protein metabolic processGO:00512483910.029
neuromuscular junction developmentGO:000752830.029
lipid metabolic processGO:00066293810.029
muscle structure developmentGO:0061061980.028
negative regulation of cell deathGO:00605483450.028
negative regulation of catalytic activityGO:00430863350.028
epithelium developmentGO:00604292270.028
positive regulation of cellular amino acid metabolic processGO:004576430.028
segmentationGO:003528240.027
hindbrain developmentGO:003090230.027
interspecies interaction between organismsGO:00444191560.027
nucleoside catabolic processGO:00091644080.027
cellular amino acid metabolic processGO:00065201160.027
ribonucleoside triphosphate catabolic processGO:00092033910.027
limbic system developmentGO:002176130.027
cell part morphogenesisGO:00329901370.027
organophosphate catabolic processGO:00464344300.027
kidney developmentGO:0001822530.026
ribonucleoside catabolic processGO:00424544060.026
cellular macromolecule catabolic processGO:00442653800.026
Mouse
cellular lipid metabolic processGO:00442553030.026
regulation of cellular amine metabolic processGO:0033238110.026
neuron fate commitmentGO:004866320.025
mapk cascadeGO:00001652880.025
immune responseGO:00069553070.025
chemical homeostasisGO:00488783060.025
metencephalon developmentGO:002203720.025
rho protein signal transductionGO:0007266260.025
regulation of transferase activityGO:00513383550.025
positive regulation of purine nucleotide metabolic processGO:19005442270.025
cellular macromolecular complex assemblyGO:00346223240.025
cellular amine metabolic processGO:0044106410.024
regulation of cellular ketone metabolic processGO:0010565500.024
negative regulation of phosphorus metabolic processGO:00105632670.024
biological adhesionGO:00226103310.024
positive regulation of phosphorylationGO:00423273940.024
regulation of cell developmentGO:00602841610.024
Mouse
positive regulation of cellular component organizationGO:00511303760.024
glycosyl compound catabolic processGO:19016584130.024
viral life cycleGO:00190581320.024
regulation of mapk cascadeGO:00434082620.024
nucleoside triphosphate metabolic processGO:00091414220.024
nucleocytoplasmic transportGO:00069131760.023
apoptotic signaling pathwayGO:00971902680.023
purine nucleotide catabolic processGO:00061954050.023
positive regulation of transportGO:00510503360.023
negative regulation of cellular component organizationGO:00511292350.023
secretionGO:00469032540.023
neurogenesisGO:00220081690.023
Mouse
forebrain regionalizationGO:002187130.023
digestive tract developmentGO:0048565750.023
positive regulation of locomotionGO:00400171860.023
blood vessel morphogenesisGO:00485141620.023
lipid biosynthetic processGO:00086101770.023
forebrain dorsal ventral pattern formationGO:002179810.023
glial cell migrationGO:000834740.022
small molecule biosynthetic processGO:00442831570.022
cellular response to oxygen containing compoundGO:19017012760.022
positive regulation of cell motilityGO:20001471770.022
morphogenesis of embryonic epitheliumGO:001633140.022
response to oxygen containing compoundGO:19017003690.022
neuron differentiationGO:00301821380.022
Mouse
purine ribonucleoside catabolic processGO:00461303980.022
rhythmic behaviorGO:000762220.022
anterior posterior axis specificationGO:000994820.022
regenerationGO:003109940.022
cell growthGO:00160491600.022
anatomical structure formation involved in morphogenesisGO:00486462840.021
regulation of purine nucleotide metabolic processGO:19005422640.021
ribonucleotide catabolic processGO:00092614050.021
hemopoiesisGO:00300971800.021
negative regulation of phosphate metabolic processGO:00459362670.021
positive regulation of apoptotic processGO:00430652460.021
regulation of meiotic cell cycleGO:005144540.021
purine ribonucleoside triphosphate metabolic processGO:00092054110.021
ras protein signal transductionGO:0007265730.021
regulation of growthGO:00400081650.021
regulation of protein localizationGO:00328802960.021
organelle assemblyGO:00709251760.021
kidney epithelium developmentGO:0072073250.021
regulation of nucleotide metabolic processGO:00061402690.021
regulation of heart growthGO:006042040.021
membrane organizationGO:00610242920.020
posttranscriptional regulation of gene expressionGO:00106082130.020
nitrogen compound transportGO:00717051910.020
regulation of proteolysisGO:00301622930.020
negative regulation of programmed cell deathGO:00430693210.020
nucleoside triphosphate catabolic processGO:00091433940.020
cardiovascular system developmentGO:00723582620.020
syncytium formation by plasma membrane fusionGO:000076820.020
gtp metabolic processGO:00460392390.019
regulation of gtp catabolic processGO:00331241800.019
regulation of meiosisGO:004002030.019
purine ribonucleotide catabolic processGO:00091544040.019
regulation of cellular amino acid metabolic processGO:000652160.019
response to cytokineGO:00340972320.019
regulation of kinase activityGO:00435493140.019
photoreceptor cell differentiationGO:004653020.019
regulation of apoptotic signaling pathwayGO:20012331750.018
positive regulation of cell proliferationGO:00082843010.018
neuron projection developmentGO:00311751060.018
organophosphate biosynthetic processGO:00904071630.018
amine metabolic processGO:0009308440.018
convergent extensionGO:006002610.018
positive regulation of cell differentiationGO:00455972110.018
Human
response to other organismGO:00517072610.018
digestive system developmentGO:0055123750.018
cellular ketone metabolic processGO:0042180800.018
immune system developmentGO:00025201950.018
cation transportGO:00068123310.018
forebrain generation of neuronsGO:002187230.018
metal ion transportGO:00300012720.018
cation transmembrane transportGO:00986552380.018
positive regulation of gtpase activityGO:00435471660.018
primary neural tube formationGO:001402030.018
positive regulation of nucleoside metabolic processGO:00459791860.018
negative regulation of cellular amino acid metabolic processGO:004576320.017
negative regulation of intracellular signal transductionGO:19025321830.017
negative regulation of phosphorylationGO:00423261740.017
single organism membrane organizationGO:00448022680.017
regulation of cellular component movementGO:00512703340.017
regulation of cytoskeleton organizationGO:00514931770.017
nucleoside phosphate catabolic processGO:19012924120.017
single organism cellular localizationGO:19025803320.017
negative regulation of multicellular organismal processGO:00512413170.017
Mouse
regulation of sequence specific dna binding transcription factor activityGO:00510902110.017
renal sodium ion absorptionGO:007029420.017
neuron developmentGO:00486661130.017
cell projection morphogenesisGO:00488581290.017
regulation of synaptic plasticityGO:004816730.017
cell activationGO:00017752130.017
protein ubiquitinationGO:00165673140.017
embryo developmentGO:00097901230.016
release of cytoplasmic sequestered nf kappabGO:000858840.016
regulation of cell growthGO:00015581350.016
negative regulation of transportGO:00510511760.016
regulation of anatomical structure morphogenesisGO:00226032860.016
negative regulation of hydrolase activityGO:00513461820.016
positive regulation of hydrolase activityGO:00513453310.016
organonitrogen compound biosynthetic processGO:19015662000.016
inner ear morphogenesisGO:004247240.016
response to radiationGO:00093141510.016
establishment of protein localization to organelleGO:00725941720.016
spermatid developmentGO:000728640.016
visual behaviorGO:000763220.016
positive regulation of organelle organizationGO:00106381950.016
ossificationGO:00015031210.016
Human
negative regulation of cellular amine metabolic processGO:003323930.016
nucleotide catabolic processGO:00091664080.016
positive regulation of cellular catabolic processGO:00313312840.016
positive regulation of programmed cell deathGO:00430682490.016
ribonucleoside triphosphate metabolic processGO:00091994120.016
mitotic cell cycle processGO:19030472860.016
oocyte developmentGO:004859910.016
purine ribonucleoside metabolic processGO:00461284370.016
regulation of cellular response to stressGO:00801352440.016
angiogenesisGO:00015251470.016
spermatid differentiationGO:004851540.016
compound eye developmentGO:004874910.016
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.016
rna processingGO:00063962550.016
cell cycle phase transitionGO:00447701730.016
regulation of ossificationGO:0030278580.016
Human
oxidation reduction processGO:00551143960.016
somatic muscle developmentGO:000752510.016
regulation of intracellular transportGO:00323861950.016
purine nucleoside catabolic processGO:00061523980.015
positive regulation of cell deathGO:00109422630.015
ion homeostasisGO:00508012300.015
central nervous system developmentGO:00074171230.015
visual learningGO:000854210.015
embryonic epithelial tube formationGO:000183840.015
wnt signaling pathwayGO:00160551560.015
protein targetingGO:00066051870.015
regulation of actin filament based processGO:00329701410.015
regulation of protein transportGO:00512232130.015
nephric duct developmentGO:007217640.015
regulation of protein complex assemblyGO:00432541470.015
hematopoietic stem cell differentiationGO:006021840.015
peripheral nervous system developmentGO:000742220.015
multi organism cellular processGO:00447641560.015
blood vessel developmentGO:00015681720.015
protein catabolic processGO:00301633250.015
regulation of response to external stimulusGO:00321012220.015
tube morphogenesisGO:0035239950.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.015
positive regulation of cellular component biogenesisGO:00440891580.015
somitogenesisGO:000175620.015
negative regulation of protein modification processGO:00314002000.015
circadian behaviorGO:004851220.015
cell divisionGO:00513011680.014
regulation of homeostatic processGO:00328441210.014
embryonic placenta developmentGO:000189210.014
regulation of cell divisionGO:00513021160.014
chromatin organizationGO:00063253510.014
mitochondrion organizationGO:00070051560.014
sensory perception of painGO:001923340.014
neural crest cell migrationGO:000175520.014
protein oligomerizationGO:00512591730.014
response to lipidGO:00339932060.014
histone modificationGO:00165702510.014
negative regulation of cell cycleGO:00457861930.014
carbohydrate metabolic processGO:00059752070.014
renal system developmentGO:0072001630.014
regulation of locomotionGO:00400123290.014
innate immune responseGO:00450871780.014
motor neuron axon guidanceGO:000804520.014
chemotaxisGO:00069351570.014
gtp catabolic processGO:00061842370.014
protein modification by small protein conjugationGO:00324463420.014
convergent extension involved in gastrulationGO:006002710.014
symbiosis encompassing mutualism through parasitismGO:00444031560.014
translationGO:00064121320.014
regulation of establishment of protein localizationGO:00702012420.014
cellular protein complex assemblyGO:00436231880.014
pituitary gland developmentGO:002198320.014
cell proliferation in forebrainGO:002184610.014
neuroblast divisionGO:005505710.014
behaviorGO:00076101120.014
positive regulation of protein phosphorylationGO:00019343130.014
regulation of membrane potentialGO:0042391950.014
cerebellum developmentGO:002154920.014
negative regulation of developmental processGO:00510932470.014
Mouse
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.014
intrinsic apoptotic signaling pathwayGO:00971931270.014
positive regulation of cell migrationGO:00303351720.014
actin filament based movementGO:0030048170.014
tripartite regional subdivisionGO:000735120.013
oocyte differentiationGO:000999420.013
protein maturationGO:00516042330.013
maintenance of locationGO:00512351120.013
hippocampus developmentGO:002176610.013
intracellular protein transportGO:00068862700.013
response to external biotic stimulusGO:00432072610.013
organ formationGO:004864530.013
negative regulation of cell differentiationGO:00455961710.013
Mouse
spinal cord developmentGO:002151040.013
regulation of excitatory postsynaptic membrane potentialGO:006007910.013
neural tube formationGO:000184130.013
purine containing compound catabolic processGO:00725234110.013
response to fungusGO:000962040.013
regulation of protein catabolic processGO:00421761550.013
chromatin modificationGO:00165682980.013
regulation of ras gtpase activityGO:00323181280.013
organic hydroxy compound metabolic processGO:19016151470.013
endomembrane system organizationGO:00102561960.013
regulation of neural precursor cell proliferationGO:200017740.013
regulation of cell migrationGO:00303342890.013
regulation of gtpase activityGO:00430871800.013
positive regulation of gliogenesisGO:001401540.013
modification dependent macromolecule catabolic processGO:00436322120.013
single organism carbohydrate metabolic processGO:00447231930.013
secretion by cellGO:00329402260.013
carbohydrate derivative biosynthetic processGO:19011372070.013
regulation of nervous system developmentGO:0051960880.013
Mouse
purine ribonucleoside triphosphate catabolic processGO:00092073910.012
nuclear importGO:00511701060.012
head developmentGO:00603221080.012
cellular homeostasisGO:00197251960.012
regulation of multi organism processGO:00439001570.012
pericardium developmentGO:006003920.012
sleepGO:003043120.012
axis elongationGO:000340140.012
embryonic morphogenesisGO:0048598850.012
defense responseGO:00069523150.012
negative regulation of organelle organizationGO:00106391260.012
regulation of cardiac muscle cell proliferationGO:006004340.012
receptor internalizationGO:0031623430.012
dna repairGO:00062811980.012
inorganic cation transmembrane transportGO:00986621940.012
regulation of nucleoside metabolic processGO:00091182090.012
t cell differentiation in thymusGO:003307740.012
negative regulation of kinase activityGO:00336731060.012
guanosine containing compound metabolic processGO:19010682440.012
single organism nuclear importGO:19025931040.012
negative regulation of peptidase activityGO:0010466910.012
viral processGO:00160321460.012
positive regulation of cardiac muscle cell proliferationGO:006004520.012
tissue morphogenesisGO:0048729960.012
mrna processingGO:00063971330.012
cardiac muscle cell contractionGO:008600340.012
purine nucleoside triphosphate catabolic processGO:00091463920.012
eye photoreceptor cell differentiationGO:000175420.012
proteolysis involved in cellular protein catabolic processGO:00516032440.012
peptidyl lysine modificationGO:00182051440.012
regulation of canonical wnt signaling pathwayGO:0060828880.012
ribonucleoside monophosphate metabolic processGO:00091611870.012
regulation of protein kinase activityGO:00458592890.012
myoblast fusionGO:000752010.012
regulation of cell motilityGO:20001452990.012
regulation of i kappab kinase nf kappab signalingGO:00431221620.012
mesodermal cell fate specificationGO:000750120.012
hematopoietic or lymphoid organ developmentGO:00485341860.012
positive regulation of protein catabolic processGO:0045732750.012
reactive oxygen species biosynthetic processGO:190340940.012
tissue regenerationGO:004224630.012
nucleoside monophosphate metabolic processGO:00091231910.012
regulation of reactive oxygen species metabolic processGO:2000377410.012
distal tubule developmentGO:007201740.012
ion transmembrane transportGO:00342203380.012
monovalent inorganic cation transportGO:00156721280.012
positive regulation of immune system processGO:00026842830.012
leukocyte proliferationGO:0070661740.012
tube closureGO:006060630.012
regulation of wnt signaling pathwayGO:00301111230.012
protein polyubiquitinationGO:00002091100.012
regulation of reactive oxygen species biosynthetic processGO:190342630.012
cell morphogenesis involved in differentiationGO:00009041440.012
protein methylationGO:0006479740.012
lung alveolus developmentGO:004828640.012
cyclic nucleotide metabolic processGO:0009187820.012
alcohol metabolic processGO:00060661140.012
positive regulation of cellular amine metabolic processGO:003324070.012
response to organonitrogen compoundGO:00102431560.012
microtubule based processGO:00070172100.012
divalent inorganic cation transportGO:00725111580.012
establishment or maintenance of apical basal cell polarityGO:003508820.012
proteasomal protein catabolic processGO:00104981760.012
i kappab kinase nf kappab signalingGO:00072491660.012
protein acylationGO:00435431380.011
response to biotic stimulusGO:00096072760.011
cellular protein catabolic processGO:00442572610.011
behavioral response to ethanolGO:004814920.011
response to light stimulusGO:0009416870.011
membrane lipid metabolic processGO:0006643530.011
protein localization to plasma membraneGO:0072659930.011
purine nucleoside monophosphate metabolic processGO:00091261860.011
positive regulation of nucleotide metabolic processGO:00459812300.011
protein alkylationGO:0008213740.011
response to axon injuryGO:004867810.011
nerve developmentGO:002167540.011
post embryonic organ developmentGO:004856910.011
neuroblast proliferationGO:000740540.011
rna splicingGO:00083801310.011
protein import into nucleusGO:00066061040.011
positive regulation of gtp catabolic processGO:00331261660.011
golgi vesicle transportGO:0048193800.011
purine ribonucleoside monophosphate metabolic processGO:00091671860.011
methylationGO:00322591060.011
negative regulation of growthGO:0045926970.011
transmembrane transportGO:00550853990.011
ribonucleoprotein complex biogenesisGO:00226131160.011
negative regulation of protein processingGO:00109551420.011
positive regulation of ras gtpase activityGO:00323201170.011
regulation of protein processingGO:00706131500.011
specification of organ identityGO:001009230.011
chromosome passenger complex localization to spindle midzoneGO:003585310.011
protein localization to nucleusGO:00345041360.011
regulation of endopeptidase activityGO:00525481700.011
response to uvGO:0009411730.011
neural tube closureGO:000184330.011
ribonucleoprotein complex subunit organizationGO:0071826810.011
negative regulation of synaptic transmissionGO:005080520.011
protein localization to membraneGO:00726571600.011
stress activated protein kinase signaling cascadeGO:0031098940.011
regulation of secretion by cellGO:19035301770.011
response to oxygen levelsGO:00704821000.011
guanosine containing compound catabolic processGO:19010692390.011
startle responseGO:000196430.011
positive regulation of cellular component movementGO:00512721810.011
organ morphogenesisGO:00098871470.011
regulation of cell morphogenesisGO:00226041530.011
myosin filament organizationGO:003103320.011
neurotransmitter secretionGO:000726940.011
protein processingGO:00164852260.011
divalent metal ion transportGO:00708381520.011
sebaceous gland developmentGO:004873310.011
cellular response to organonitrogen compoundGO:00714171240.011
inorganic ion transmembrane transportGO:00986602310.011
regulation of purine nucleotide catabolic processGO:00331212050.011
anterior posterior axis specification embryoGO:000859520.010
cilium morphogenesisGO:0060271750.010
matingGO:000761810.010
macromolecule methylationGO:0043414970.010
renal sodium ion transportGO:000309620.010
atp metabolic processGO:00460341760.010
mitotic cell cycle phase transitionGO:00447721620.010
response to nitrogen compoundGO:19016981840.010
canonical wnt signaling pathwayGO:00600701160.010
microtubule cytoskeleton organizationGO:00002261760.010
establishment of tissue polarityGO:000716430.010
negative regulation of transferase activityGO:00513481240.010
gastrulation with mouth forming secondGO:000170210.010
trabecula morphogenesisGO:006138320.010
myeloid cell differentiationGO:00300991170.010
plasma membrane organizationGO:00070091150.010
regulation of ion transportGO:00432691890.010
cytokine productionGO:00018162470.010
leukocyte activationGO:00453211640.010
peptidyl lysine acetylationGO:00183941010.010
protein autophosphorylationGO:00467771230.010
positive regulation of ossificationGO:0045778320.010
Human
cellular chemical homeostasisGO:00550821800.010
cell cycle arrestGO:0007050710.010
response to transforming growth factor betaGO:0071559940.010
regulation of nucleotide catabolic processGO:00308112050.010
establishment of nucleus localizationGO:004002310.010
positive regulation of protein kinase activityGO:00458601900.010
histone methylationGO:0016571600.010

ZHX2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
eye diseaseDOID:56141490.033
eye and adnexa diseaseDOID:14921500.033
nervous system diseaseDOID:8634310.033
sensory system diseaseDOID:00501552030.033
muscle tissue diseaseDOID:661130.033
muscular diseaseDOID:00800001140.033
myopathyDOID:4231040.033
musculoskeletal system diseaseDOID:172230.033
central nervous system diseaseDOID:3311860.023
meckel syndromeDOID:0050778110.022
disease of metabolismDOID:00146672950.019
neurodegenerative diseaseDOID:12891020.018
muscular dystrophyDOID:9884510.016
disease of cellular proliferationDOID:145661740.014
cancerDOID:1621670.013
retinal diseaseDOID:56791180.013
organ system cancerDOID:00506861640.012
retinal degenerationDOID:8466890.011
cardiovascular system diseaseDOID:12871060.011