Homo sapiens

48 known processes

FTO

fat mass and obesity associated

(Aliases: KIAA1752,MGC5149)

FTO biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.064
cellular amino acid metabolic processGO:00065201160.060
ras protein signal transductionGO:0007265730.058
regulation of cellular amino acid metabolic processGO:000652160.053
cellular ketone metabolic processGO:0042180800.051
cellular amine metabolic processGO:0044106410.051
regulation of cellular amine metabolic processGO:0033238110.047
regulation of cellular ketone metabolic processGO:0010565500.046
segmentationGO:003528240.043
associative learningGO:000830610.037
oogenesisGO:004847720.036
nervous system developmentGO:00073992930.035
negative regulation of cellular protein metabolic processGO:00322693530.035
locomotory behaviorGO:000762610.033
amine metabolic processGO:0009308440.033
memoryGO:000761330.032
multicellular organismal agingGO:001025930.032
female gamete generationGO:000729220.031
cytoplasmic transportGO:00164823790.030
negative regulation of protein metabolic processGO:00512483910.030
glycosyl compound catabolic processGO:19016584130.029
cellular macromolecule catabolic processGO:00442653800.029
single organism cellular localizationGO:19025803320.029
blastoderm segmentationGO:000735020.029
oxidation reduction processGO:00551143960.028
ribonucleoside triphosphate catabolic processGO:00092033910.028
vesicle mediated transportGO:00161923710.027
purine ribonucleoside metabolic processGO:00461284370.027
determination of adult lifespanGO:000834020.027
system processGO:00030083490.026
response to abiotic stimulusGO:00096283360.026
ribonucleoside triphosphate metabolic processGO:00091994120.026
ribonucleoside catabolic processGO:00424544060.026
protein catabolic processGO:00301633250.026
organophosphate catabolic processGO:00464344300.026
small gtpase mediated signal transductionGO:0007264780.025
cell projection organizationGO:00300302520.025
nucleoside triphosphate metabolic processGO:00091414220.025
nucleoside triphosphate catabolic processGO:00091433940.025
cellular component morphogenesisGO:00329893140.025
protein modification by small protein conjugationGO:00324463420.025
cell morphogenesisGO:00009022960.024
purine nucleoside triphosphate metabolic processGO:00091444120.024
regulation of locomotionGO:00400123290.024
anterior posterior axis specification embryoGO:000859520.024
purine containing compound catabolic processGO:00725234110.023
regulation of cell differentiationGO:00455953930.023
regulation of cellular component movementGO:00512703340.022
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.022
oocyte differentiationGO:000999420.022
cellular response to dna damage stimulusGO:00069743790.022
nucleotide catabolic processGO:00091664080.022
positive regulation of cellular amino acid metabolic processGO:004576430.022
purine nucleotide catabolic processGO:00061954050.022
positive regulation of catabolic processGO:00098963100.022
purine ribonucleoside triphosphate metabolic processGO:00092054110.022
protein localization to organelleGO:00333652800.021
regulation of anatomical structure morphogenesisGO:00226032860.021
anterior posterior axis specificationGO:000994820.021
purine nucleoside triphosphate catabolic processGO:00091463920.021
negative regulation of catalytic activityGO:00430863350.021
inorganic ion transmembrane transportGO:00986602310.021
cellular response to endogenous stimulusGO:00714953360.021
neurological system processGO:00508771630.021
protein processingGO:00164852260.020
purine ribonucleoside catabolic processGO:00461303980.020
protein maturationGO:00516042330.020
positive regulation of cellular amine metabolic processGO:003324070.020
negative regulation of multicellular organismal processGO:00512413170.020
regenerationGO:003109940.020
response to oxygen containing compoundGO:19017003690.020
proteolysis involved in cellular protein catabolic processGO:00516032440.020
regulation of cell cycleGO:00517263930.020
oocyte developmentGO:004859910.020
negative regulation of cellular amine metabolic processGO:003323930.019
cardiac muscle cell contractionGO:008600340.019
biological adhesionGO:00226103310.019
neuromuscular junction developmentGO:000752830.019
negative regulation of phosphate metabolic processGO:00459362670.019
organonitrogen compound biosynthetic processGO:19015662000.019
nucleoside phosphate catabolic processGO:19012924120.019
immune responseGO:00069553070.019
positive regulation of cellular component organizationGO:00511303760.019
microtubule based processGO:00070172100.019
rho protein signal transductionGO:0007266260.019
actin filament based processGO:00300292240.019
carbohydrate derivative biosynthetic processGO:19011372070.019
posttranscriptional regulation of gene expressionGO:00106082130.018
negative regulation of phosphorus metabolic processGO:00105632670.018
regulation of sequence specific dna binding transcription factor activityGO:00510902110.018
small molecule catabolic processGO:0044282920.018
cellular lipid metabolic processGO:00442553030.018
purine ribonucleoside monophosphate metabolic processGO:00091671860.018
ion transmembrane transportGO:00342203380.018
positive regulation of purine nucleotide metabolic processGO:19005442270.018
cell adhesionGO:00071553250.018
cation transmembrane transportGO:00986552380.018
tripartite regional subdivisionGO:000735120.018
mitotic cell cycleGO:00002783260.018
regulation of nucleotide metabolic processGO:00061402690.018
secretion by cellGO:00329402260.017
regulation of kinase activityGO:00435493140.017
regulation of transferase activityGO:00513383550.017
regulation of proteolysisGO:00301622930.017
adult locomotory behaviorGO:000834410.017
positive regulation of hydrolase activityGO:00513453310.017
regulation of ras protein signal transductionGO:00465781550.017
cellular response to oxygen containing compoundGO:19017012760.017
regulation of protein localizationGO:00328802960.017
dephosphorylationGO:00163112090.017
gtp metabolic processGO:00460392390.017
apoptotic signaling pathwayGO:00971902680.017
positive regulation of transportGO:00510503360.017
positive regulation of cellular catabolic processGO:00313312840.017
cellular protein catabolic processGO:00442572610.017
positive regulation of cell proliferationGO:00082843010.017
secretionGO:00469032540.017
rhythmic behaviorGO:000762220.017
reactive oxygen species biosynthetic processGO:190340940.017
metencephalon developmentGO:002203720.017
endocytosisGO:00068971590.017
protein ubiquitinationGO:00165673140.017
negative regulation of cellular amino acid metabolic processGO:004576320.017
chemical homeostasisGO:00488783060.016
positive regulation of phosphorylationGO:00423273940.016
neurotransmitter secretionGO:000726940.016
purine nucleoside monophosphate metabolic processGO:00091261860.016
proteasomal protein catabolic processGO:00104981760.016
mitotic cell cycle processGO:19030472860.016
nucleoside catabolic processGO:00091644080.016
regulation of cellular response to stressGO:00801352440.016
purine ribonucleotide catabolic processGO:00091544040.016
microtubule cytoskeleton organizationGO:00002261760.016
response to external biotic stimulusGO:00432072610.016
chromatin organizationGO:00063253510.016
protein oligomerizationGO:00512591730.016
purine ribonucleoside triphosphate catabolic processGO:00092073910.016
defense responseGO:00069523150.016
negative regulation of cellular component organizationGO:00511292350.016
maintenance of locationGO:00512351120.016
guanosine containing compound catabolic processGO:19010692390.016
cellular macromolecular complex assemblyGO:00346223240.016
gtp catabolic processGO:00061842370.016
regulation of cell morphogenesisGO:00226041530.016
actin filament based movementGO:0030048170.016
embryonic epithelial tube formationGO:000183840.016
circadian behaviorGO:004851220.016
negative regulation of cell proliferationGO:00082852280.015
regulation of purine nucleotide catabolic processGO:00331212050.015
ribonucleotide catabolic processGO:00092614050.015
hindbrain developmentGO:003090230.015
nucleoside monophosphate metabolic processGO:00091231910.015
positive regulation of nucleotide metabolic processGO:00459812300.015
cerebellum developmentGO:002154920.015
sleepGO:003043120.015
ion homeostasisGO:00508012300.015
peripheral nervous system developmentGO:000742220.015
atp metabolic processGO:00460341760.015
actin mediated cell contractionGO:0070252120.015
morphogenesis of embryonic epitheliumGO:001633140.015
regulation of small gtpase mediated signal transductionGO:00510561560.015
transmembrane transportGO:00550853990.015
mapk cascadeGO:00001652880.015
ribonucleoside monophosphate metabolic processGO:00091611870.015
regulation of protein kinase activityGO:00458592890.015
regulation of cell motilityGO:20001452990.015
striated muscle contractionGO:0006941520.015
regulation of cell migrationGO:00303342890.015
regulation of purine nucleotide metabolic processGO:19005422640.015
cell divisionGO:00513011680.015
membrane organizationGO:00610242920.014
modification dependent macromolecule catabolic processGO:00436322120.014
modification dependent protein catabolic processGO:00199412090.014
positive regulation of programmed cell deathGO:00430682490.014
regulation of secretion by cellGO:19035301770.014
single organism membrane organizationGO:00448022680.014
regulation of protein processingGO:00706131500.014
positive regulation of immune system processGO:00026842830.014
histone modificationGO:00165702510.014
cellular chemical homeostasisGO:00550821800.014
regulation of protein maturationGO:19033171500.014
cell cycle phase transitionGO:00447701730.014
purine nucleoside catabolic processGO:00061523980.014
neural tube formationGO:000184130.014
tissue migrationGO:00901301190.014
regulation of neurotransmitter secretionGO:004692830.014
regulation of nucleoside metabolic processGO:00091182090.014
regulation of protein catabolic processGO:00421761550.014
primary neural tube formationGO:001402030.014
positive regulation of apoptotic processGO:00430652460.014
cellular homeostasisGO:00197251960.014
positive regulation of protein phosphorylationGO:00019343130.014
negative regulation of programmed cell deathGO:00430693210.014
spermatid differentiationGO:004851540.014
nitrogen compound transportGO:00717051910.014
ubiquitin dependent protein catabolic processGO:00065112060.014
monocarboxylic acid metabolic processGO:00327871850.014
photoreceptor cell differentiationGO:004653020.014
signal transduction by phosphorylationGO:00230142970.014
response to axon injuryGO:004867810.014
negative regulation of protein modification processGO:00314002000.013
chromosome segregationGO:00070591140.013
negative regulation of intracellular signal transductionGO:19025321830.013
regulation of mapk cascadeGO:00434082620.013
positive regulation of reactive oxygen species biosynthetic processGO:190342820.013
lipid metabolic processGO:00066293810.013
axon cargo transportGO:000808820.013
reactive nitrogen species metabolic processGO:200105730.013
negative regulation of cell deathGO:00605483450.013
regulation of secretionGO:00510461940.013
compound eye developmentGO:004874910.013
negative regulation of protein processingGO:00109551420.013
protein localization to membraneGO:00726571600.013
organophosphate biosynthetic processGO:00904071630.013
positive regulation of nucleotide catabolic processGO:00308131850.013
lipid biosynthetic processGO:00086101770.013
positive regulation of developmental processGO:00510943140.013
response to biotic stimulusGO:00096072760.013
regulation of reactive oxygen species biosynthetic processGO:190342630.013
intracellular protein transportGO:00068862700.013
response to other organismGO:00517072610.013
establishment or maintenance of cytoskeleton polarityGO:003095230.013
positive regulation of gtp catabolic processGO:00331261660.013
single organismal cell cell adhesionGO:00163371480.013
matingGO:000761810.013
single organism carbohydrate metabolic processGO:00447231930.013
chromatin modificationGO:00165682980.013
innate immune responseGO:00450871780.013
inner ear morphogenesisGO:004247240.013
positive regulation of nucleoside metabolic processGO:00459791860.013
regulation of synaptic plasticityGO:004816730.013
endomembrane system organizationGO:00102561960.013
positive regulation of synaptic transmissionGO:005080640.013
regulation of transporter activityGO:0032409820.013
cell projection assemblyGO:00300311260.012
organ formationGO:004864530.012
retinal ganglion cell axon guidanceGO:003129020.012
negative regulation of cell cycleGO:00457861930.012
regulation of establishment of protein localizationGO:00702012420.012
cell part morphogenesisGO:00329901370.012
neuron projection regenerationGO:003110210.012
negative regulation of developmental processGO:00510932470.012
positive regulation of purine nucleotide catabolic processGO:00331231850.012
motor neuron axon guidanceGO:000804520.012
negative regulation of protein maturationGO:19033181420.012
regulation of cell adhesionGO:00301551660.012
guanosine containing compound metabolic processGO:19010682440.012
regulation of multi organism processGO:00439001570.012
cofactor metabolic processGO:0051186870.012
plasma membrane organizationGO:00070091150.012
cell developmentGO:00484683280.012
regulation of cell developmentGO:00602841610.012
negative regulation of apoptotic processGO:00430663160.012
positive regulation of cell deathGO:00109422630.012
axon regenerationGO:003110310.012
negative regulation of phosphorylationGO:00423261740.012
regulation of dna metabolic processGO:00510521530.012
taxisGO:00423301570.012
neuroblast proliferationGO:000740540.012
hematopoietic or lymphoid organ developmentGO:00485341860.012
inorganic cation transmembrane transportGO:00986621940.012
organelle assemblyGO:00709251760.012
regulation of cellular component biogenesisGO:00440872810.012
regulation of ion transportGO:00432691890.012
negative regulation of organelle organizationGO:00106391260.012
regulation of cell cycle processGO:00105642660.012
negative regulation of protein phosphorylationGO:00019331400.012
sex determinationGO:000753030.012
salivary gland morphogenesisGO:000743540.012
epithelium migrationGO:00901321190.012
neuron developmentGO:00486661130.012
cellular protein complex assemblyGO:00436231880.012
epithelial cell proliferationGO:00506731280.012
metal ion homeostasisGO:00550651690.011
regulation of meiotic cell cycleGO:005144540.011
response to radiationGO:00093141510.011
cation transportGO:00068123310.011
regulation of cytoplasmic transportGO:19036491490.011
mitotic cell cycle phase transitionGO:00447721620.011
nuclear migrationGO:000709710.011
organelle fissionGO:00482851490.011
cilium morphogenesisGO:0060271750.011
spinal cord developmentGO:002151040.011
establishment or maintenance of microtubule cytoskeleton polarityGO:003095120.011
cell projection morphogenesisGO:00488581290.011
nuclear transportGO:00511691790.011
regulation of ion transmembrane transportGO:00347651320.011
regulation of intracellular transportGO:00323861950.011
somatic muscle developmentGO:000752510.011
long term memoryGO:000761620.011
response to nitrogen compoundGO:19016981840.011
enzyme linked receptor protein signaling pathwayGO:00071673030.011
regulation of gtpase activityGO:00430871800.011
actin cytoskeleton organizationGO:00300362070.011
sequestering of calcium ionGO:0051208170.011
regulation of protein transportGO:00512232130.011
regulation of circadian sleep wake cycle sleepGO:004518720.011
metal ion transportGO:00300012720.011
muscle system processGO:0003012810.011
protein targetingGO:00066051870.011
sensory perception of painGO:001923340.011
circulatory system developmentGO:00723592620.011
rna interferenceGO:001624640.011
cilium assemblyGO:0042384630.011
regulation of feeding behaviorGO:006025930.011
neuron projection developmentGO:00311751060.011
positive regulation of gtpase activityGO:00435471660.011
glycerolipid metabolic processGO:00464861070.011
internal protein amino acid acetylationGO:00064751010.011
cell cycle checkpointGO:00000751170.011
positive regulation of mesonephros developmentGO:006121320.011
negative regulation of smoothened signaling pathwayGO:004587930.011
nerve developmentGO:002167540.011
regulation of gtp catabolic processGO:00331241800.011
protein acylationGO:00435431380.011
regulation of immune responseGO:00507762010.011
visual behaviorGO:000763220.011
epithelium developmentGO:00604292270.011
regulation of nucleotide catabolic processGO:00308112050.011
divalent inorganic cation transportGO:00725111580.011
convergent extensionGO:006002610.011
calcium ion transmembrane transportGO:0070588760.011
regulation of homeostatic processGO:00328441210.011
divalent metal ion transportGO:00708381520.011
meiotic chromosome segregationGO:004513240.011
anion transportGO:00068201610.011
positive regulation of mapk cascadeGO:00434101900.011
regulation of ras gtpase activityGO:00323181280.011
response to fungusGO:000962040.011
reactive oxygen species metabolic processGO:0072593750.011
tube closureGO:006060630.011
blood circulationGO:00080151130.011
dna repairGO:00062811980.011
response to inorganic substanceGO:00100351270.011
response to woundingGO:00096111680.011
regulation of metal ion transportGO:00109591200.010
covalent chromatin modificationGO:00165692540.010
glycerophospholipid metabolic processGO:0006650840.010
regulation of cytoskeleton organizationGO:00514931770.010
positive regulation of transferase activityGO:00513472270.010
ameboidal type cell migrationGO:00016671350.010
organic acid catabolic processGO:0016054710.010
positive regulation of cell differentiationGO:00455972110.010
syncytium formation by plasma membrane fusionGO:000076820.010
carbohydrate metabolic processGO:00059752070.010
negative regulation of blood pressureGO:004577630.010
spermatid developmentGO:000728640.010
cellular cation homeostasisGO:00300031630.010
cell substrate adhesionGO:00315891320.010
epithelial cell migrationGO:00106311190.010
cell growthGO:00160491600.010
nucleus localizationGO:005164710.010
purine ribonucleoside monophosphate catabolic processGO:00091691580.010
regulation of protein serine threonine kinase activityGO:00719001790.010
negative regulation of synaptic transmissionGO:005080520.010
regulation of actin filament based processGO:00329701410.010
immune system developmentGO:00025201950.010
calcium ion transportGO:00068161470.010
neuron differentiationGO:00301821380.010
coenzyme metabolic processGO:0006732650.010
regulation of apoptotic signaling pathwayGO:20012331750.010
negative regulation of cell differentiationGO:00455961710.010
regulation of cell cycle phase transitionGO:19019871260.010
regulation of glial cell differentiationGO:004568530.010
negative regulation of locomotionGO:00400131180.010
generation of neuronsGO:00486991520.010
peptidyl lysine modificationGO:00182051440.010
cellular ion homeostasisGO:00068731680.010

FTO disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.089
inherited metabolic disorderDOID:6552420.064
glycogen metabolism disorderDOID:0050728100.055
glycogen storage diseaseDOID:2747100.055
carbohydrate metabolic disorderDOID:2978550.055
nervous system diseaseDOID:8634310.035
central nervous system diseaseDOID:3311860.035
musculoskeletal system diseaseDOID:172230.027
neurodegenerative diseaseDOID:12891020.026
sensory system diseaseDOID:00501552030.018
cardiovascular system diseaseDOID:12871060.018
connective tissue diseaseDOID:651090.017
immune system diseaseDOID:29141550.016
muscle tissue diseaseDOID:661130.015
myopathyDOID:4231040.015
muscular diseaseDOID:00800001140.015
disease of cellular proliferationDOID:145661740.014
organ system cancerDOID:00506861640.014
cancerDOID:1621670.014
bone diseaseDOID:0080001880.013
hematopoietic system diseaseDOID:741000.012
eye and adnexa diseaseDOID:14921500.012
eye diseaseDOID:56141490.012
brain diseaseDOID:936730.011
retinal diseaseDOID:56791180.010