Homo sapiens

0 known processes

EIF4A1

eukaryotic translation initiation factor 4A1

(Aliases: eIF4A-I,DDX2A,EIF4A,EIF-4A,eIF-4A-I)

EIF4A1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
translationGO:00064121320.994
Yeast
translational initiationGO:0006413480.980
Yeast
regulation of translationGO:0006417890.976
posttranscriptional regulation of gene expressionGO:00106082130.808
regulation of translational initiationGO:0006446240.763
post embryonic developmentGO:000979120.728
Worm
rna splicing via transesterification reactionsGO:0000375900.681
Fly
mrna processingGO:00063971330.660
Fly
purine ribonucleoside triphosphate metabolic processGO:00092054110.580
Yeast
determination of adult lifespanGO:000834020.565
Worm
lipid localizationGO:00108761060.502
Worm
mrna metabolic processGO:00160711750.501
Fly
stem cell developmentGO:0048864690.500
Fly
female gamete generationGO:000729220.490
Fly
microtubule cytoskeleton organizationGO:00002261760.478
Fly
purine ribonucleoside monophosphate metabolic processGO:00091671860.389
Yeast
rna catabolic processGO:0006401710.357
nucleoside triphosphate metabolic processGO:00091414220.333
Yeast
cellular homeostasisGO:00197251960.329
growthGO:00400072020.326
ribonucleotide biosynthetic processGO:0009260810.268
rna splicingGO:00083801310.265
Fly
protein secretionGO:0009306980.255
mrna catabolic processGO:0006402560.255
nucleoside catabolic processGO:00091644080.224
Yeast
lipid storageGO:0019915280.217
Worm
cellular response to oxidative stressGO:0034599850.207
positive regulation of developmental processGO:00510943140.199
oogenesisGO:004847720.195
Fly
response to other organismGO:00517072610.187
embryo developmentGO:00097901230.186
Worm
ribonucleoprotein complex biogenesisGO:00226131160.185
cellular macromolecular complex assemblyGO:00346223240.182
ribonucleoside triphosphate metabolic processGO:00091994120.177
Yeast
apoptotic signaling pathwayGO:00971902680.177
cytoplasmic transportGO:00164823790.173
organelle assemblyGO:00709251760.172
cellular amine metabolic processGO:0044106410.171
glomerular mesangial cell developmentGO:007214410.169
cell activationGO:00017752130.167
multicellular organismal agingGO:001025930.166
Worm
mrna splicing via spliceosomeGO:0000398890.166
Fly
negative regulation of cell deathGO:00605483450.165
ribonucleoside catabolic processGO:00424544060.164
Yeast
organonitrogen compound biosynthetic processGO:19015662000.164
circulatory system developmentGO:00723592620.164
reproductionGO:0000003630.152
Worm Fly
nucleoside phosphate catabolic processGO:19012924120.150
Yeast
cytoplasmic translational initiationGO:000218360.149
atp metabolic processGO:00460341760.147
Yeast
purine ribonucleoside catabolic processGO:00461303980.143
Yeast
microtubule organizing center organizationGO:0031023620.140
Fly
maintenance of locationGO:00512351120.135
Worm
anatomical structure formation involved in morphogenesisGO:00486462840.134
Fly
cellular macromolecule catabolic processGO:00442653800.131
purine nucleoside catabolic processGO:00061523980.126
Yeast
response to virusGO:00096151260.125
negative regulation of programmed cell deathGO:00430693210.124
rna processingGO:00063962550.122
Fly
mitotic spindle elongationGO:000002240.121
Fly
regulation of oxidative phosphorylationGO:000208230.120
oocyte developmentGO:004859910.119
negative regulation of cellular component organizationGO:00511292350.117
cell developmentGO:00484683280.116
Fly
purine nucleoside triphosphate metabolic processGO:00091444120.115
Yeast
purine ribonucleoside monophosphate catabolic processGO:00091691580.114
Yeast
cellular response to cytokine stimulusGO:00713451810.113
purine ribonucleoside metabolic processGO:00461284370.111
Yeast
oocyte differentiationGO:000999420.110
reproductive processGO:00224141060.106
Fly
cellular chemical homeostasisGO:00550821800.105
nucleoside triphosphate catabolic processGO:00091433940.099
Yeast
amine metabolic processGO:0009308440.097
tube developmentGO:00352951250.097
toxin transportGO:190199840.096
cell growthGO:00160491600.094
putrescine metabolic processGO:000944520.094
nucleotide biosynthetic processGO:00091651090.092
multi organism cellular processGO:00447641560.092
positive regulation of cell proliferationGO:00082843010.091
purine containing compound catabolic processGO:00725234110.090
Yeast
t cell activationGO:0042110990.088
blastoderm segmentationGO:000735020.087
cardiovascular system developmentGO:00723582620.084
regulation of transporter activityGO:0032409820.084
cellular hyperosmotic responseGO:007147440.082
nucleotide catabolic processGO:00091664080.081
Yeast
locomotory behaviorGO:000762610.079
carbohydrate derivative biosynthetic processGO:19011372070.077
glycosyl compound catabolic processGO:19016584130.076
Yeast
lymphocyte activationGO:00466491330.075
transmembrane transportGO:00550853990.073
secretion by cellGO:00329402260.073
negative regulation of apoptotic signaling pathwayGO:2001234970.072
developmental growthGO:0048589480.070
single organism carbohydrate metabolic processGO:00447231930.069
muscle cell cellular homeostasisGO:004671630.069
intracellular protein transportGO:00068862700.068
gtp metabolic processGO:00460392390.067
ribose phosphate biosynthetic processGO:0046390820.067
regenerationGO:003109940.066
Rat
cofactor metabolic processGO:0051186870.065
nuclear transcribed mrna catabolic processGO:0000956480.064
cation homeostasisGO:00550801890.063
positive regulation of transferase activityGO:00513472270.063
regulation of protein complex assemblyGO:00432541470.063
mitochondrion organizationGO:00070051560.061
regulation of translational initiation in response to stressGO:004355810.060
regulation of multi organism processGO:00439001570.059
microtubule based processGO:00070172100.059
Fly
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046210.058
negative regulation of apoptotic processGO:00430663160.057
adult locomotory behaviorGO:000834410.056
chordate embryonic developmentGO:0043009340.056
ribonucleoside monophosphate catabolic processGO:00091581580.055
Yeast
chemical homeostasisGO:00488783060.054
secretionGO:00469032540.054
carbohydrate metabolic processGO:00059752070.053
negative regulation of cell growthGO:0030308830.052
cellular ion homeostasisGO:00068731680.052
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243400.051
nucleoside phosphate biosynthetic processGO:19012931090.051
sex differentiationGO:0007548450.051
purine ribonucleoside triphosphate catabolic processGO:00092073910.049
Yeast
single organism reproductive processGO:0044702980.047
Fly
regulation of growthGO:00400081650.046
inflammatory responseGO:0006954790.046
purine nucleoside triphosphate catabolic processGO:00091463920.045
Yeast
positive regulation of transportGO:00510503360.045
single organism cell adhesionGO:00986021790.045
protein localization to organelleGO:00333652800.045
response to tumor cellGO:0002347100.045
negative regulation of cellular protein metabolic processGO:00322693530.044
oxidation reduction processGO:00551143960.044
membrane organizationGO:00610242920.044
reproductive structure developmentGO:0048608550.043
viral life cycleGO:00190581320.043
nucleoside monophosphate catabolic processGO:00091251590.043
Yeast
response to nitrogen compoundGO:19016981840.043
regulation of anatomical structure morphogenesisGO:00226032860.042
response to organonitrogen compoundGO:00102431560.041
purine nucleotide catabolic processGO:00061954050.041
Yeast
positive regulation of immune system processGO:00026842830.041
negative regulation of protein metabolic processGO:00512483910.041
negative regulation of mrna catabolic processGO:190237340.040
reproductive system developmentGO:0061458560.040
mesenchymal cell developmentGO:0014031500.040
single organism membrane organizationGO:00448022680.040
neuron differentiationGO:00301821380.040
response to abiotic stimulusGO:00096283360.039
ribonucleoside triphosphate catabolic processGO:00092033910.039
Yeast
nucleic acid transportGO:0050657390.039
establishment or maintenance of cytoskeleton polarityGO:003095230.038
positive regulation of cellular amine metabolic processGO:003324070.038
purine nucleoside monophosphate catabolic processGO:00091281580.038
Yeast
immune effector processGO:00022521590.038
renal system developmentGO:0072001630.038
ribosome biogenesisGO:0042254480.038
leukocyte proliferationGO:0070661740.038
negative regulation of catalytic activityGO:00430863350.037
response to external biotic stimulusGO:00432072610.037
response to hormoneGO:00097251750.037
regulation of t cell activationGO:0050863770.036
regulation of nucleotide metabolic processGO:00061402690.036
renal interstitial fibroblast developmentGO:007214110.035
lipid metabolic processGO:00066293810.035
mitotic cell cycle phase transitionGO:00447721620.035
positive regulation of apoptotic processGO:00430652460.035
response to oxidative stressGO:00069791210.035
nitrogen compound transportGO:00717051910.035
cell adhesionGO:00071553250.035
leukocyte activationGO:00453211640.035
single organism cellular localizationGO:19025803320.035
regulation of cell activationGO:00508651250.035
regulation of cell cycle processGO:00105642660.034
system processGO:00030083490.034
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.034
spindle elongationGO:005123140.033
Fly
positive regulation of cellular amino acid metabolic processGO:004576430.033
cellular cation homeostasisGO:00300031630.032
positive regulation of nucleotide metabolic processGO:00459812300.031
cellular metal ion homeostasisGO:00068751460.030
regulation of purine nucleotide metabolic processGO:19005422640.030
g1 s transition of mitotic cell cycleGO:0000082780.030
ribonucleoprotein complex localizationGO:007116640.030
ribonucleoside monophosphate metabolic processGO:00091611870.030
Yeast
response to acid chemicalGO:0001101660.030
protein autophosphorylationGO:00467771230.029
negative regulation of neuron deathGO:1901215320.029
purine ribonucleotide catabolic processGO:00091544040.029
Yeast
organophosphate biosynthetic processGO:00904071630.029
cellular response to oxygen containing compoundGO:19017012760.029
mononuclear cell proliferationGO:0032943710.029
cell morphogenesisGO:00009022960.029
protein targetingGO:00066051870.028
developmental process involved in reproductionGO:0003006660.028
Fly
interspecies interaction between organismsGO:00444191560.027
maturation of ssu rrnaGO:003049030.027
cellular component morphogenesisGO:00329893140.027
regulation of mitochondrion organizationGO:0010821540.027
regulation of cell adhesionGO:00301551660.027
negative regulation of growthGO:0045926970.027
negative regulation of organelle organizationGO:00106391260.027
ribonucleotide catabolic processGO:00092614050.026
Yeast
regulation of mrna metabolic processGO:1903311530.026
Fly
regulation of cell migrationGO:00303342890.026
regionalizationGO:0003002290.026
Fly
intrinsic apoptotic signaling pathwayGO:00971931270.026
mitotic cell cycle processGO:19030472860.026
Fly
regulation of rna splicingGO:0043484620.026
Fly
ion transmembrane transportGO:00342203380.025
taxisGO:00423301570.025
nucleoside triphosphate biosynthetic processGO:0009142200.025
purine nucleoside triphosphate biosynthetic processGO:0009145110.025
spindle organizationGO:0007051530.025
Fly
positive regulation of hydrolase activityGO:00513453310.024
positive regulation of multi organism processGO:0043902560.024
ribosomal subunit export from nucleusGO:000005440.024
regulation of apoptotic signaling pathwayGO:20012331750.024
regulation of developmental growthGO:0048638300.024
ribonucleoside biosynthetic processGO:0042455250.024
positive regulation of translationGO:0045727350.024
response to woundingGO:00096111680.023
regulation of atp metabolic processGO:1903578290.023
agingGO:0007568660.023
Worm
intrinsic apoptotic signaling pathway in response to osmotic stressGO:000862720.023
cellular response to dna damage stimulusGO:00069743790.023
Fly
regulation of cellular amine metabolic processGO:0033238110.023
regulation of peptidase activityGO:00525471800.023
sexual reproductionGO:0019953370.022
Fly
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.022
nuclear transcribed mrna catabolic process nonsense mediated decayGO:0000184230.022
establishment of ribosome localizationGO:003375340.022
establishment or maintenance of cell polarityGO:0007163310.022
nucleocytoplasmic transportGO:00069131760.022
pigment biosynthetic processGO:0046148100.022
embryonic eye morphogenesisGO:004804820.021
regulation of lymphocyte activationGO:00512491030.021
negative regulation of translationGO:0017148370.021
positive regulation of developmental growthGO:0048639160.021
ribonucleoprotein complex assemblyGO:0022618780.021
tripartite regional subdivisionGO:000735120.021
guanosine containing compound catabolic processGO:19010692390.021
cellular component assembly involved in morphogenesisGO:0010927730.021
positive regulation of cell deathGO:00109422630.021
cellular amino acid metabolic processGO:00065201160.020
cytokine productionGO:00018162470.020
generation of neuronsGO:00486991520.020
multicellular organism reproductionGO:0032504420.020
Fly
response to oxygen containing compoundGO:19017003690.020
metal ion homeostasisGO:00550651690.020
regulation of cell projection organizationGO:00313441070.020
positive regulation of cellular catabolic processGO:00313312840.019
regulation of cell growthGO:00015581350.019
protein localization to membraneGO:00726571600.019
protein oligomerizationGO:00512591730.019
cell type specific apoptotic processGO:00972851250.019
positive regulation of organelle organizationGO:00106381950.019
response to metal ionGO:0010038840.019
establishment of protein localization to organelleGO:00725941720.019
protein importGO:00170381300.019
positive regulation of cell cycle processGO:00900681060.019
epithelial cell differentiationGO:00308551410.019
innate immune response activating signal transductionGO:0002758480.019
positive regulation of purine nucleotide metabolic processGO:19005442270.019
cytoplasmic translationGO:000218180.019
anterior posterior axis specificationGO:000994820.019
purine ribonucleotide biosynthetic processGO:0009152790.018
biological adhesionGO:00226103310.018
neuron deathGO:0070997650.018
regulation of cytokine productionGO:00018172320.018
photoreceptor cell differentiationGO:004653020.018
cell morphogenesis involved in differentiationGO:00009041440.018
hematopoietic or lymphoid organ developmentGO:00485341860.018
multicellular organismal reproductive processGO:0048609400.018
Fly
pyrimidine ribonucleoside triphosphate metabolic processGO:000920820.017
coenzyme metabolic processGO:0006732650.017
negative regulation of viral processGO:0048525660.017
negative regulation of intracellular signal transductionGO:19025321830.017
peptidyl serine phosphorylationGO:00181051010.017
cellular protein complex assemblyGO:00436231880.017
negative regulation of developmental processGO:00510932470.017
Fly
ribonucleoprotein complex subunit organizationGO:0071826810.017
response to calcium ionGO:0051592460.017
heart developmentGO:0007507950.017
negative regulation of multi organism processGO:0043901920.017
regulation of response to woundingGO:19030341010.017
response to biotic stimulusGO:00096072760.017
response to cytokineGO:00340972320.017
programmed necrotic cell deathGO:0097300180.017
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.017
peptidyl serine modificationGO:00182091060.017
regulation of ion transportGO:00432691890.016
regulation of neurogenesisGO:0050767820.016
necroptotic processGO:0070266160.016
embryonic morphogenesisGO:0048598850.016
purine nucleotide biosynthetic processGO:0006164840.016
regulation of membrane potentialGO:0042391950.016
negative regulation of necroptotic processGO:006054620.016
positive regulation of cell differentiationGO:00455972110.016
lymphocyte proliferationGO:0046651700.015
cellular biogenic amine metabolic processGO:0006576340.015
neurogenesisGO:00220081690.015
anterior posterior axis specification embryoGO:000859520.015
tube morphogenesisGO:0035239950.015
positive regulation of protein secretionGO:0050714600.015
spermatid differentiationGO:004851540.015
positive regulation of erk1 and erk2 cascadeGO:0070374750.015
developmental maturationGO:0021700280.015
regulation of mrna processingGO:0050684480.015
Fly
development of primary sexual characteristicsGO:0045137350.015
ossificationGO:00015031210.015
mitochondrial membrane organizationGO:0007006400.014
peptidyl tyrosine modificationGO:00182121700.014
regulation of meiotic cell cycleGO:005144540.014
negative regulation of hydrolase activityGO:00513461820.014
regulation of homeostatic processGO:00328441210.014
neurological system processGO:00508771630.014
inorganic anion transmembrane transportGO:0098661470.014
negative regulation of cellular catabolic processGO:0031330830.014
activation of immune responseGO:00022531140.013
cellular response to organonitrogen compoundGO:00714171240.013
tissue regenerationGO:004224630.013
regulation of cell developmentGO:00602841610.013
cation transportGO:00068123310.013
regulation of cellular ketone metabolic processGO:0010565500.013
innate immune responseGO:00450871780.013
positive regulation of cellular component organizationGO:00511303760.013
divalent inorganic cation homeostasisGO:00725071360.013
cellular response to extracellular stimulusGO:0031668720.013
protein homooligomerizationGO:00512601000.013
segmentationGO:003528240.013
regulation of cell cycleGO:00517263930.013
cellular lipid metabolic processGO:00442553030.013
negative regulation of cell cycle processGO:00109481210.012
pattern recognition receptor signaling pathwayGO:0002221480.012
lymphocyte apoptotic processGO:0070227200.012
rrna processingGO:0006364350.012
neural crest cell developmentGO:001403230.012
cellular response to nitrogen compoundGO:19016991440.012
myoblast fusionGO:000752010.012
positive regulation of response to external stimulusGO:0032103880.012
pyrimidine ribonucleoside metabolic processGO:0046131110.012
positive regulation of bindingGO:0051099450.012
regulation of camp metabolic processGO:0030814520.012
cell projection organizationGO:00300302520.012
protein catabolic processGO:00301633250.012
vesicle mediated transportGO:00161923710.012
wound healingGO:00420601150.012
regulation of mitochondrial membrane potentialGO:0051881230.012
rhythmic processGO:0048511310.012
blastocyst developmentGO:000182430.012
regulation of cellular component movementGO:00512703340.012
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046620.012
actin mediated cell contractionGO:0070252120.012
central nervous system developmentGO:00074171230.012
cofactor biosynthetic processGO:0051188310.012
regulation of epithelial cell proliferationGO:00506781130.012
cell cycle g1 s phase transitionGO:0044843800.011
polyamine metabolic processGO:000659540.011
regulation of protein transportGO:00512232130.011
protein maturationGO:00516042330.011
negative regulation of multicellular organismal processGO:00512413170.011
organelle inheritanceGO:004830820.011
positive regulation of growthGO:0045927580.011
blood vessel developmentGO:00015681720.011
response to inorganic substanceGO:00100351270.011
response to oxygen levelsGO:00704821000.011
symbiosis encompassing mutualism through parasitismGO:00444031560.011
srp dependent cotranslational protein targeting to membraneGO:000661420.011
cellular response to oxygen levelsGO:0071453550.011
regulation of mrna splicing via spliceosomeGO:0048024320.011
Fly
rrna metabolic processGO:0016072400.011
nuclear divisionGO:00002801280.011
Fly
male gamete generationGO:0048232220.011
cellular divalent inorganic cation homeostasisGO:00725031280.011
regulation of leukocyte activationGO:00026941150.011
positive regulation of catabolic processGO:00098963100.011
small gtpase mediated signal transductionGO:0007264780.011
response to decreased oxygen levelsGO:0036293960.011
pyrimidine nucleoside triphosphate biosynthetic processGO:000914810.011
cellular calcium ion homeostasisGO:00068741170.010
regulation of transmembrane transportGO:00347621390.010
regulation of endopeptidase activityGO:00525481700.010
eye photoreceptor cell differentiationGO:000175420.010
negative regulation of rna catabolic processGO:190236940.010
pyrimidine ribonucleotide metabolic processGO:000921840.010
cation transmembrane transportGO:00986552380.010
rna export from nucleusGO:0006405330.010
regulation of inflammatory responseGO:0050727460.010
negative regulation of transportGO:00510511760.010
axonogenesisGO:0007409310.010
cellular ketone metabolic processGO:0042180800.010
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377890.010
Fly
gtp catabolic processGO:00061842370.010

EIF4A1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
synucleinopathyDOID:0050890220.081
neurodegenerative diseaseDOID:12891020.081
central nervous system diseaseDOID:3311860.081
nervous system diseaseDOID:8634310.081
parkinson s diseaseDOID:14330180.081
disease of cellular proliferationDOID:145661740.075
cancerDOID:1621670.025
organ system cancerDOID:00506861640.025
sensory system diseaseDOID:00501552030.018
disease of mental healthDOID:150700.017
developmental disorder of mental healthDOID:0060037290.013