Homo sapiens

53 known processes

CHFR

checkpoint with forkhead and ring finger domains

(Aliases: RNF116,RNF196,FLJ33629,FLJ10796)

CHFR biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein polyubiquitinationGO:00002091100.989
protein modification by small protein conjugationGO:00324463420.976
protein ubiquitinationGO:00165673140.808
protein k48 linked ubiquitinationGO:0070936380.467
Human
histone ubiquitinationGO:0016574310.419
Human
proteolysis involved in cellular protein catabolic processGO:00516032440.414
protein autoubiquitinationGO:0051865370.393
Human
ubiquitin dependent protein catabolic processGO:00065112060.293
Human Mouse
protein catabolic processGO:00301633250.290
cellular protein catabolic processGO:00442572610.262
cellular macromolecule catabolic processGO:00442653800.241
modification dependent macromolecule catabolic processGO:00436322120.196
modification dependent protein catabolic processGO:00199412090.191
chromatin modificationGO:00165682980.170
Human
protein monoubiquitinationGO:0006513390.132
regulation of response to dna damage stimulusGO:2001020940.116
Human
post embryonic developmentGO:000979120.114
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787370.102
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.092
Mouse
cellular response to dna damage stimulusGO:00069743790.083
Human
protein maturationGO:00516042330.071
proteasomal protein catabolic processGO:00104981760.067
Mouse
chromatin organizationGO:00063253510.063
Human
regulation of cellular response to stressGO:00801352440.063
Human
cell cycle phase transitionGO:00447701730.062
i kappab kinase nf kappab signalingGO:00072491660.062
regulation of cell cycleGO:00517263930.060
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.057
segmentationGO:003528240.055
actin filament based processGO:00300292240.054
mitotic cell cycle processGO:19030472860.051
regulation of cell cycle processGO:00105642660.048
covalent chromatin modificationGO:00165692540.045
Human
histone modificationGO:00165702510.045
Human
locomotory behaviorGO:000762610.044
actin cytoskeleton organizationGO:00300362070.044
cellular amino acid metabolic processGO:00065201160.041
amine metabolic processGO:0009308440.041
regulation of mitotic cell cycleGO:00073461890.041
negative regulation of protein metabolic processGO:00512483910.041
negative regulation of cell cycleGO:00457861930.040
negative regulation of cell deathGO:00605483450.040
anterior posterior axis specificationGO:000994820.040
mitotic cell cycleGO:00002783260.038
cell developmentGO:00484683280.038
purine containing compound catabolic processGO:00725234110.037
growthGO:00400072020.036
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.036
cellular macromolecular complex assemblyGO:00346223240.036
negative regulation of apoptotic processGO:00430663160.036
negative regulation of catalytic activityGO:00430863350.035
regulation of i kappab kinase nf kappab signalingGO:00431221620.034
positive regulation of cell cycleGO:00457871400.034
nervous system developmentGO:00073992930.034
organelle assemblyGO:00709251760.033
purine nucleoside catabolic processGO:00061523980.033
defense responseGO:00069523150.033
cellular component morphogenesisGO:00329893140.032
positive regulation of catabolic processGO:00098963100.031
Mouse
interleukin 2 secretionGO:007097030.031
transmembrane transportGO:00550853990.030
blastoderm segmentationGO:000735020.030
negative regulation of protein maturationGO:19033181420.030
cation transportGO:00068123310.030
female gamete generationGO:000729220.029
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.029
Mouse
response to oxygen containing compoundGO:19017003690.029
immune responseGO:00069553070.029
cellular protein complex assemblyGO:00436231880.029
purine ribonucleoside metabolic processGO:00461284370.029
system processGO:00030083490.029
organelle fissionGO:00482851490.028
protein processingGO:00164852260.028
dna repairGO:00062811980.028
Human
single organism membrane organizationGO:00448022680.028
negative regulation of gliogenesisGO:001401430.028
cell projection organizationGO:00300302520.027
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.027
Human
neuromuscular junction developmentGO:000752830.027
regulation of locomotionGO:00400123290.027
protein polymerizationGO:0051258710.027
regulation of response to external stimulusGO:00321012220.027
regulation of cellular ketone metabolic processGO:0010565500.027
purine nucleotide catabolic processGO:00061954050.027
immune response activating signal transductionGO:0002757900.026
metal ion transportGO:00300012720.026
negative regulation of phosphate metabolic processGO:00459362670.026
negative regulation of cellular protein metabolic processGO:00322693530.026
vesicle mediated transportGO:00161923710.026
ribonucleoside triphosphate metabolic processGO:00091994120.025
organophosphate catabolic processGO:00464344300.025
morphogenesis of embryonic epitheliumGO:001633140.025
memoryGO:000761330.025
tripartite regional subdivisionGO:000735120.025
ribonucleoside triphosphate catabolic processGO:00092033910.024
regulation of protein ubiquitinationGO:0031396950.024
Mouse
positive regulation of cellular component organizationGO:00511303760.024
positive regulation of cellular amino acid metabolic processGO:004576430.024
glycosyl compound catabolic processGO:19016584130.024
regulation of proteolysisGO:00301622930.024
Mouse
defense response to virusGO:0051607710.024
response to bacteriumGO:00096171440.024
cell morphogenesisGO:00009022960.024
regulation of protein localizationGO:00328802960.024
protein k63 linked ubiquitinationGO:0070534310.023
Human
adult locomotory behaviorGO:000834410.023
nucleotide catabolic processGO:00091664080.023
regulation of endopeptidase activityGO:00525481700.023
positive regulation of phosphorylationGO:00423273940.023
regulation of cellular amino acid metabolic processGO:000652160.023
regulation of cellular amine metabolic processGO:0033238110.023
regulation of sequence specific dna binding transcription factor activityGO:00510902110.023
oogenesisGO:004847720.023
negative regulation of multicellular organismal processGO:00512413170.023
ion transmembrane transportGO:00342203380.023
multicellular organismal agingGO:001025930.023
regulation of dna repairGO:0006282470.023
Human
positive regulation of immune system processGO:00026842830.023
regulation of cell cycle phase transitionGO:19019871260.022
nucleoside triphosphate metabolic processGO:00091414220.022
regulation of mitotic cell cycle phase transitionGO:19019901180.022
negative regulation of developmental processGO:00510932470.022
interspecies interaction between organismsGO:00444191560.022
neurogenesisGO:00220081690.022
positive regulation of mitotic cell cycleGO:0045931600.022
blastocyst developmentGO:000182430.022
actin filament organizationGO:00070151280.022
microtubule based processGO:00070172100.022
regulation of protein maturationGO:19033171500.022
small gtpase mediated signal transductionGO:0007264780.022
regulation of interleukin 2 secretionGO:190004020.022
cell adhesionGO:00071553250.022
regulation of cytoskeleton organizationGO:00514931770.022
cellular ketone metabolic processGO:0042180800.022
positive regulation of cellular catabolic processGO:00313312840.021
Mouse
regulation of dna metabolic processGO:00510521530.021
Human
anatomical structure formation involved in morphogenesisGO:00486462840.021
regenerationGO:003109940.021
reactive oxygen species metabolic processGO:0072593750.021
positive regulation of proteolysisGO:00458621420.021
Mouse
purine ribonucleoside triphosphate catabolic processGO:00092073910.021
response to lipidGO:00339932060.021
negative regulation of hydrolase activityGO:00513461820.021
negative regulation of phosphorus metabolic processGO:00105632670.021
lipid metabolic processGO:00066293810.021
organ morphogenesisGO:00098871470.021
ras protein signal transductionGO:0007265730.020
membrane organizationGO:00610242920.020
purine nucleoside triphosphate metabolic processGO:00091444120.020
regulation of cytokine productionGO:00018172320.020
regulation of protein processingGO:00706131500.020
positive regulation of nf kappab transcription factor activityGO:0051092810.020
apoptotic signaling pathwayGO:00971902680.020
determination of adult lifespanGO:000834020.020
negative regulation of phosphorylationGO:00423261740.020
posttranscriptional regulation of gene expressionGO:00106082130.020
Mouse
ribonucleotide catabolic processGO:00092614050.020
dephosphorylationGO:00163112090.020
immune effector processGO:00022521590.020
nucleoside triphosphate catabolic processGO:00091433940.020
neural tube formationGO:000184130.020
purine ribonucleoside catabolic processGO:00461303980.019
negative regulation of viral processGO:0048525660.019
negative regulation of organelle organizationGO:00106391260.019
embryonic epithelial tube formationGO:000183840.019
regulation of kinase activityGO:00435493140.019
response to biotic stimulusGO:00096072760.019
cytokine productionGO:00018162470.019
ribonucleoside catabolic processGO:00424544060.019
chromosome segregationGO:00070591140.019
response to abiotic stimulusGO:00096283360.019
Human
positive regulation of organelle organizationGO:00106381950.019
regulation of viral release from host cellGO:1902186200.019
canonical wnt signaling pathwayGO:00600701160.018
negative regulation of cell differentiationGO:00455961710.018
positive regulation of cell proliferationGO:00082843010.018
cellular amine metabolic processGO:0044106410.018
viral release from host cellGO:0019076210.018
meiotic chromosome segregationGO:004513240.018
mapk cascadeGO:00001652880.018
purine nucleoside triphosphate catabolic processGO:00091463920.018
generation of neuronsGO:00486991520.018
nucleic acid phosphodiester bond hydrolysisGO:00903051020.018
hindbrain developmentGO:003090230.018
regulation of anatomical structure morphogenesisGO:00226032860.018
positive regulation of viral entry into host cellGO:004659830.018
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:200005930.018
response to ionizing radiationGO:0010212650.018
Human
nucleoside phosphate catabolic processGO:19012924120.018
photoreceptor cell differentiationGO:004653020.018
histone h2a ubiquitinationGO:0033522170.017
Human
cell growthGO:00160491600.017
response to external biotic stimulusGO:00432072610.017
androgen receptor signaling pathwayGO:0030521340.017
regulation of synaptic plasticityGO:004816730.017
positive regulation of programmed cell deathGO:00430682490.017
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.017
signal transduction by phosphorylationGO:00230142970.017
cellular response to endogenous stimulusGO:00714953360.017
regulation of neural precursor cell proliferationGO:200017740.017
biological adhesionGO:00226103310.017
cerebral cortex radially oriented cell migrationGO:002179910.017
viral life cycleGO:00190581320.017
negative regulation of catabolic processGO:00098951040.017
regulation of cysteine type endopeptidase activityGO:20001161270.017
response to cytokineGO:00340972320.016
negative regulation of ion transportGO:0043271390.016
chemical homeostasisGO:00488783060.016
negative regulation of cellular amine metabolic processGO:003323930.016
symbiosis encompassing mutualism through parasitismGO:00444031560.016
negative regulation of cellular amino acid metabolic processGO:004576320.016
negative regulation of cell proliferationGO:00082852280.016
cell cycle checkpointGO:00000751170.016
positive regulation of cytokine productionGO:00018191670.016
regulation of transferase activityGO:00513383550.016
regulation of apoptotic signaling pathwayGO:20012331750.016
double strand break repairGO:00063021010.016
Human
anion transportGO:00068201610.016
nucleoside catabolic processGO:00091644080.016
cellular homeostasisGO:00197251960.016
motor neuron axon guidanceGO:000804520.016
regulation of viral processGO:00507921030.016
cellular response to lipidGO:00713961270.016
negative regulation of protein processingGO:00109551420.015
positive regulation of protein ubiquitinationGO:0031398530.015
Mouse
ribonucleoside monophosphate metabolic processGO:00091611870.015
innate immune responseGO:00450871780.015
regulation of protein complex assemblyGO:00432541470.015
spermatid differentiationGO:004851540.015
purine ribonucleoside triphosphate metabolic processGO:00092054110.015
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.015
oocyte differentiationGO:000999420.015
regulation of mapk cascadeGO:00434082620.015
positive regulation of cell cycle processGO:00900681060.015
regulation of transcription during mitosisGO:004589620.015
positive regulation of transferase activityGO:00513472270.015
regulation of purine nucleotide metabolic processGO:19005422640.015
regulation of multi organism processGO:00439001570.015
oocyte developmentGO:004859910.015
regulation of chromosome organizationGO:00330441030.015
purine ribonucleotide catabolic processGO:00091544040.015
autophagyGO:0006914880.015
positive regulation of cellular amine metabolic processGO:003324070.015
regulation of meiotic cell cycleGO:005144540.015
response to other organismGO:00517072610.015
regulation of cell differentiationGO:00455953930.015
peripheral nervous system developmentGO:000742220.015
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.015
protein localization to organelleGO:00333652800.015
regulation of microtubule based processGO:0032886740.015
regulation of cell morphogenesisGO:00226041530.014
negative regulation of endopeptidase activityGO:0010951840.014
regulation of gene expression epigeneticGO:0040029730.014
positive regulation of developmental processGO:00510943140.014
cellular lipid metabolic processGO:00442553030.014
cerebral cortex cell migrationGO:002179530.014
negative regulation of cell cycle processGO:00109481210.014
nuclear divisionGO:00002801280.014
regulation of protein kinase activityGO:00458592890.014
divalent inorganic cation transportGO:00725111580.014
regulation of protein modification by small protein conjugation or removalGO:19033201070.014
Mouse
regulation of cell motilityGO:20001452990.014
carbohydrate metabolic processGO:00059752070.014
tube developmentGO:00352951250.014
negative regulation of programmed cell deathGO:00430693210.014
regulation of wnt signaling pathwayGO:00301111230.014
regulation of cellular component movementGO:00512703340.014
positive regulation of neural precursor cell proliferationGO:200017920.014
positive regulation of transportGO:00510503360.014
positive regulation of cell deathGO:00109422630.014
negative regulation of transportGO:00510511760.014
regulation of protein transportGO:00512232130.014
regulation of nucleoside metabolic processGO:00091182090.014
secretionGO:00469032540.014
regulation of microtubule cytoskeleton organizationGO:0070507610.014
establishment of protein localization to membraneGO:00901501210.014
spermatid developmentGO:000728640.014
regulation of immune responseGO:00507762010.014
endomembrane system organizationGO:00102561960.014
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.014
dna recombinationGO:0006310770.014
response to virusGO:00096151260.014
reactive oxygen species biosynthetic processGO:190340940.013
regulation of protein catabolic processGO:00421761550.013
Mouse
negative regulation of calcium ion importGO:009028110.013
protein k11 linked ubiquitinationGO:0070979240.013
regulation of reactive oxygen species metabolic processGO:2000377410.013
regulation of protein polyubiquitinationGO:190291480.013
double strand break repair via homologous recombinationGO:0000724500.013
response to organic cyclic compoundGO:00140702040.013
protein oligomerizationGO:00512591730.013
er associated ubiquitin dependent protein catabolic processGO:0030433310.013
neurological system processGO:00508771630.013
regulation of intracellular steroid hormone receptor signaling pathwayGO:0033143320.013
regulation of protein secretionGO:0050708860.013
positive regulation of cellular component biogenesisGO:00440891580.013
long term memoryGO:000761620.013
positive regulation of transcription during mitosisGO:004589720.013
positive regulation of locomotionGO:00400171860.013
regulation of secretionGO:00510461940.013
positive regulation of purine nucleotide metabolic processGO:19005442270.013
regulation of neurogenesisGO:0050767820.013
nucleoside monophosphate metabolic processGO:00091231910.013
somitogenesisGO:000175620.013
negative regulation of proteolysisGO:00458611320.013
regulation of metal ion transportGO:00109591200.013
cellular response to external stimulusGO:00714961110.013
negative regulation of cellular component organizationGO:00511292350.013
response to oxidative stressGO:00069791210.013
mitotic cell cycle phase transitionGO:00447721620.013
cell part morphogenesisGO:00329901370.013
immune response regulating signaling pathwayGO:0002764970.013
divalent metal ion transportGO:00708381520.013
histone monoubiquitinationGO:0010390200.013
spinal cord developmentGO:002151040.013
guanosine containing compound metabolic processGO:19010682440.013
regulation of peptidase activityGO:00525471800.012
nerve developmentGO:002167540.012
limbic system developmentGO:002176130.012
intracellular steroid hormone receptor signaling pathwayGO:0030518610.012
recombinational repairGO:0000725500.012
regulation of growthGO:00400081650.012
response to fungusGO:000962040.012
regulation of actin filament based processGO:00329701410.012
purine nucleoside monophosphate metabolic processGO:00091261860.012
regulation of glial cell proliferationGO:006025140.012
oxidation reduction processGO:00551143960.012
intrinsic apoptotic signaling pathwayGO:00971931270.012
microtubule organizing center organizationGO:0031023620.012
activation of immune responseGO:00022531140.012
positive regulation of immune responseGO:00507781590.012
negative regulation of wnt signaling pathwayGO:0030178690.012
engulfment of apoptotic cellGO:004365220.012
negative regulation of peptidase activityGO:0010466910.012
regulation of cytokine secretionGO:0050707570.012
positive regulation of nucleotide metabolic processGO:00459812300.012
inorganic ion transmembrane transportGO:00986602310.012
regulation of cell developmentGO:00602841610.012
intracellular receptor signaling pathwayGO:00305221040.012
negative regulation of protein modification processGO:00314002000.012
nuclear migrationGO:000709710.012
cell activationGO:00017752130.012
retrograde transport endosome to golgiGO:0042147450.012
wnt signaling pathwayGO:00160551560.012
reactive nitrogen species metabolic processGO:200105730.012
negative regulation of transferase activityGO:00513481240.012
negative regulation of response to dna damage stimulusGO:2001021330.012
regulation of cell growthGO:00015581350.012
regulation of ion transportGO:00432691890.012
negative regulation of apoptotic signaling pathwayGO:2001234970.012
regulation of reactive oxygen species biosynthetic processGO:190342630.012
negative regulation of intracellular signal transductionGO:19025321830.012
glycoprotein biosynthetic processGO:0009101910.012
regulation of calcium ion transportGO:0051924790.012
regulation of secretion by cellGO:19035301770.012
negative regulation of cysteine type endopeptidase activityGO:2000117480.012
meiosis iGO:000712740.012
zymogen activationGO:0031638700.011
compound eye developmentGO:004874910.011
cell fate determinationGO:000170930.011
negative regulation of protein phosphorylationGO:00019331400.011
cellular response to glucocorticoid stimulusGO:007138540.011
response to radiationGO:00093141510.011
Human
mitochondrion organizationGO:00070051560.011
regulation of transmembrane transportGO:00347621390.011
regulation of nucleotide metabolic processGO:00061402690.011
cellular cation homeostasisGO:00300031630.011
dosage compensationGO:000754930.011
negative regulation of viral release from host cellGO:1902187120.011
response to extracellular stimulusGO:0009991850.011
regulation of cellular component biogenesisGO:00440872810.011
atp metabolic processGO:00460341760.011
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043154460.011
t cell differentiation in thymusGO:003307740.011
regulation of purine nucleotide catabolic processGO:00331212050.011
small molecule biosynthetic processGO:00442831570.011
regulation of ion transmembrane transportGO:00347651320.011
circadian behaviorGO:004851220.011
positive regulation of cell migrationGO:00303351720.011
purine ribonucleoside monophosphate metabolic processGO:00091671860.011
calcium ion transportGO:00068161470.011
protein dephosphorylationGO:0006470810.011
cellular ion homeostasisGO:00068731680.011
positive regulation of hydrolase activityGO:00513453310.011
regulation of homeostatic processGO:00328441210.011
regulation of canonical wnt signaling pathwayGO:0060828880.011
cellular metal ion homeostasisGO:00068751460.011
peptidyl tyrosine phosphorylationGO:00181081700.011
multi organism cellular processGO:00447641560.011
regulation of defense responseGO:00313471540.011
cofactor metabolic processGO:0051186870.011
positive regulation of cellular component movementGO:00512721810.011
regulation of intracellular transportGO:00323861950.011
positive regulation of synaptic transmissionGO:005080640.011
positive regulation of purine nucleotide catabolic processGO:00331231850.011
negative regulation of protein transportGO:0051224750.011
regulation of protein polymerizationGO:0032271630.011
positive regulation of nucleoside metabolic processGO:00459791860.011
defense response to fungusGO:005083240.011
histone h4 acetylationGO:0043967470.011
positive regulation of apoptotic processGO:00430652460.011
protein dna complex subunit organizationGO:0071824800.011
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.011
Mouse
regulation of organelle assemblyGO:1902115400.011
positive regulation of cytoskeleton organizationGO:0051495830.011
regulation of meiosisGO:004002030.011
rhythmic behaviorGO:000762220.011
regulation of vesicle mediated transportGO:00606271300.011
protein secretionGO:0009306980.011
secretion by cellGO:00329402260.011
positive regulation of myeloid cell apoptotic processGO:003303420.011
visual behaviorGO:000763220.011
cellular response to extracellular stimulusGO:0031668720.011
mrna metabolic processGO:00160711750.011
viral transcriptionGO:0019083350.011
maintenance of locationGO:00512351120.011
enzyme linked receptor protein signaling pathwayGO:00071673030.011
guanosine containing compound catabolic processGO:19010692390.011
cation transmembrane transportGO:00986552380.011
tissue regenerationGO:004224630.011
cell type specific apoptotic processGO:00972851250.011
response to axon injuryGO:004867810.011
organic acid biosynthetic processGO:0016053970.011
stem cell divisionGO:001714520.011
positive regulation of reactive oxygen species metabolic processGO:2000379240.011
negative regulation of mitotic cell cycleGO:00459301020.011
monocarboxylic acid metabolic processGO:00327871850.010
regulation of nervous system developmentGO:0051960880.010
cellular response to oxygen containing compoundGO:19017012760.010
regulation of cell migrationGO:00303342890.010
response to salt stressGO:000965130.010
negative regulation of cellular catabolic processGO:0031330830.010
response to nutrient levelsGO:0031667810.010
actin polymerization or depolymerizationGO:0008154560.010
cell projection assemblyGO:00300311260.010
ion homeostasisGO:00508012300.010
negative regulation of reactive oxygen species metabolic processGO:2000378110.010
organonitrogen compound biosynthetic processGO:19015662000.010
viral processGO:00160321460.010
positive regulation of mapk cascadeGO:00434101900.010
regulation of protein serine threonine kinase activityGO:00719001790.010
endosomal transportGO:00161971290.010
release of cytoplasmic sequestered nf kappabGO:000858840.010
negative regulation of glial cell proliferationGO:006025320.010
glycoprotein metabolic processGO:00091001100.010
anterior posterior axis specification embryoGO:000859520.010
organ formationGO:004864530.010
dna conformation changeGO:00711031130.010
regulation of actin cytoskeleton organizationGO:00329561160.010
negative regulation of cytokine productionGO:0001818820.010
sequestering of metal ionGO:0051238240.010
sulfur compound metabolic processGO:00067901010.010
sex determinationGO:000753030.010
atp catabolic processGO:00062001570.010
detection of stimulusGO:0051606850.010
negative regulation of protein polyubiquitinationGO:190291540.010
developmental growthGO:0048589480.010

CHFR disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:00501552030.028
nervous system diseaseDOID:8634310.028
disease of metabolismDOID:00146672950.027
inherited metabolic disorderDOID:6552420.027
retinal diseaseDOID:56791180.022
eye diseaseDOID:56141490.022
eye and adnexa diseaseDOID:14921500.022
musculoskeletal system diseaseDOID:172230.019
retinal degenerationDOID:8466890.019
disease of cellular proliferationDOID:145661740.018
cancerDOID:1621670.018
organ system cancerDOID:00506861640.017
immune system diseaseDOID:29141550.015
myopathyDOID:4231040.015
muscle tissue diseaseDOID:661130.015
muscular diseaseDOID:00800001140.015
retinitis pigmentosaDOID:10584510.011
connective tissue diseaseDOID:651090.010
bone diseaseDOID:0080001880.010