Homo sapiens

58 known processes

FBXL2

F-box and leucine-rich repeat protein 2

(Aliases: FBL2,FBL3,DKFZp564P0622)

FBXL2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.080
cellular amino acid metabolic processGO:00065201160.053
cellular amine metabolic processGO:0044106410.052
regulation of cellular amino acid metabolic processGO:000652160.050
regulation of cellular amine metabolic processGO:0033238110.050
organophosphate catabolic processGO:00464344300.046
ras protein signal transductionGO:0007265730.045
purine containing compound catabolic processGO:00725234110.044
determination of adult lifespanGO:000834020.044
amine metabolic processGO:0009308440.044
multicellular organismal agingGO:001025930.043
locomotory behaviorGO:000762610.043
nucleoside phosphate catabolic processGO:19012924120.043
regulation of cellular ketone metabolic processGO:0010565500.043
purine ribonucleoside metabolic processGO:00461284370.043
ribonucleoside catabolic processGO:00424544060.042
nucleoside triphosphate metabolic processGO:00091414220.042
cellular component morphogenesisGO:00329893140.042
small gtpase mediated signal transductionGO:0007264780.042
positive regulation of catabolic processGO:00098963100.041
positive regulation of cellular amino acid metabolic processGO:004576430.041
cell morphogenesisGO:00009022960.041
nervous system developmentGO:00073992930.040
ribonucleoside triphosphate catabolic processGO:00092033910.040
purine nucleotide catabolic processGO:00061954050.039
purine ribonucleoside catabolic processGO:00461303980.039
nucleoside triphosphate catabolic processGO:00091433940.039
positive regulation of cellular amine metabolic processGO:003324070.038
nucleoside catabolic processGO:00091644080.038
cell projection organizationGO:00300302520.038
cell adhesionGO:00071553250.038
female gamete generationGO:000729220.037
ribonucleotide catabolic processGO:00092614050.037
purine ribonucleotide catabolic processGO:00091544040.037
neuromuscular junction developmentGO:000752830.037
ribonucleoside triphosphate metabolic processGO:00091994120.037
cellular ketone metabolic processGO:0042180800.036
purine ribonucleoside triphosphate metabolic processGO:00092054110.036
nucleotide catabolic processGO:00091664080.036
segmentationGO:003528240.036
positive regulation of hydrolase activityGO:00513453310.036
purine nucleoside catabolic processGO:00061523980.035
cellular macromolecule catabolic processGO:00442653800.035
purine nucleoside triphosphate catabolic processGO:00091463920.035
protein catabolic processGO:00301633250.034
system processGO:00030083490.034
positive regulation of cellular catabolic processGO:00313312840.034
cell developmentGO:00484683280.034
purine nucleoside triphosphate metabolic processGO:00091444120.034
oogenesisGO:004847720.033
negative regulation of cellular component organizationGO:00511292350.033
glycosyl compound catabolic processGO:19016584130.033
cytoplasmic transportGO:00164823790.033
regulation of purine nucleotide metabolic processGO:19005422640.032
vesicle mediated transportGO:00161923710.032
positive regulation of cellular component organizationGO:00511303760.031
membrane organizationGO:00610242920.031
negative regulation of catalytic activityGO:00430863350.030
transmembrane transportGO:00550853990.030
negative regulation of protein metabolic processGO:00512483910.030
biological adhesionGO:00226103310.029
regulation of cell differentiationGO:00455953930.029
cellular macromolecular complex assemblyGO:00346223240.029
regulation of nucleotide metabolic processGO:00061402690.029
ion transmembrane transportGO:00342203380.029
gtp metabolic processGO:00460392390.028
associative learningGO:000830610.028
anterior posterior axis specificationGO:000994820.028
cellular protein catabolic processGO:00442572610.028
positive regulation of nucleotide metabolic processGO:00459812300.028
single organism cellular localizationGO:19025803320.028
purine ribonucleoside triphosphate catabolic processGO:00092073910.028
regulation of purine nucleotide catabolic processGO:00331212050.027
regulation of cell cycleGO:00517263930.027
positive regulation of purine nucleotide metabolic processGO:19005442270.027
anatomical structure formation involved in morphogenesisGO:00486462840.027
negative regulation of multicellular organismal processGO:00512413170.027
microtubule based processGO:00070172100.027
positive regulation of transportGO:00510503360.026
regulation of locomotionGO:00400123290.026
memoryGO:000761330.026
carbohydrate derivative biosynthetic processGO:19011372070.026
proteolysis involved in cellular protein catabolic processGO:00516032440.026
neuron differentiationGO:00301821380.026
negative regulation of cell deathGO:00605483450.026
positive regulation of nucleoside metabolic processGO:00459791860.026
actin filament based processGO:00300292240.025
gtp catabolic processGO:00061842370.025
guanosine containing compound metabolic processGO:19010682440.025
mitotic cell cycle processGO:19030472860.025
positive regulation of phosphorylationGO:00423273940.025
morphogenesis of embryonic epitheliumGO:001633140.025
mitotic cell cycleGO:00002783260.025
regulation of cellular component movementGO:00512703340.024
regulation of gtp catabolic processGO:00331241800.024
guanosine containing compound catabolic processGO:19010692390.024
lipid metabolic processGO:00066293810.024
regenerationGO:003109940.024
regulation of cell migrationGO:00303342890.024
protein maturationGO:00516042330.024
dephosphorylationGO:00163112090.024
positive regulation of nucleotide catabolic processGO:00308131850.024
regulation of nucleoside metabolic processGO:00091182090.024
rho protein signal transductionGO:0007266260.024
negative regulation of cellular protein metabolic processGO:00322693530.024
regulation of transferase activityGO:00513383550.024
single organism membrane organizationGO:00448022680.023
regulation of proteolysisGO:00301622930.023
regulation of anatomical structure morphogenesisGO:00226032860.023
negative regulation of apoptotic processGO:00430663160.023
blastoderm segmentationGO:000735020.023
protein modification by small protein conjugationGO:00324463420.023
positive regulation of purine nucleotide catabolic processGO:00331231850.023
ubiquitin dependent protein catabolic processGO:00065112060.023
neurogenesisGO:00220081690.023
protein processingGO:00164852260.023
microtubule cytoskeleton organizationGO:00002261760.023
regulation of kinase activityGO:00435493140.023
metal ion transportGO:00300012720.023
negative regulation of programmed cell deathGO:00430693210.023
chemical homeostasisGO:00488783060.022
organ formationGO:004864530.022
regulation of cellular component biogenesisGO:00440872810.022
immune responseGO:00069553070.022
modification dependent macromolecule catabolic processGO:00436322120.022
response to abiotic stimulusGO:00096283360.022
negative regulation of phosphate metabolic processGO:00459362670.022
neurotransmitter secretionGO:000726940.022
modification dependent protein catabolic processGO:00199412090.022
cation transportGO:00068123310.022
cellular lipid metabolic processGO:00442553030.022
regulation of nucleotide catabolic processGO:00308112050.021
cell projection morphogenesisGO:00488581290.021
negative regulation of phosphorus metabolic processGO:00105632670.021
hindbrain developmentGO:003090230.021
positive regulation of gtp catabolic processGO:00331261660.021
cellular response to dna damage stimulusGO:00069743790.021
maintenance of locationGO:00512351120.021
regulation of cytoskeleton organizationGO:00514931770.021
regulation of cell cycle processGO:00105642660.021
positive regulation of synaptic transmissionGO:005080640.021
positive regulation of protein phosphorylationGO:00019343130.021
negative regulation of hydrolase activityGO:00513461820.021
regulation of cellular response to stressGO:00801352440.020
regulation of synaptic plasticityGO:004816730.020
oocyte differentiationGO:000999420.020
ion homeostasisGO:00508012300.020
cardiovascular system developmentGO:00723582620.020
protein ubiquitinationGO:00165673140.020
single organism cell adhesionGO:00986021790.020
motor neuron axon guidanceGO:000804520.020
inorganic cation transmembrane transportGO:00986621940.020
signal transduction by phosphorylationGO:00230142970.020
cell projection assemblyGO:00300311260.020
release of cytoplasmic sequestered nf kappabGO:000858840.019
apoptotic signaling pathwayGO:00971902680.019
adult locomotory behaviorGO:000834410.019
generation of neuronsGO:00486991520.019
protein localization to organelleGO:00333652800.019
inorganic ion transmembrane transportGO:00986602310.019
proteasomal protein catabolic processGO:00104981760.019
negative regulation of cellular amine metabolic processGO:003323930.019
cellular protein complex assemblyGO:00436231880.019
cation homeostasisGO:00550801890.019
oocyte developmentGO:004859910.019
regulation of mapk cascadeGO:00434082620.019
negative regulation of cellular amino acid metabolic processGO:004576320.019
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.019
regulation of cell growthGO:00015581350.019
organelle assemblyGO:00709251760.019
negative regulation of cell proliferationGO:00082852280.019
cell part morphogenesisGO:00329901370.019
intracellular protein transportGO:00068862700.019
positive regulation of cell deathGO:00109422630.019
cell growthGO:00160491600.019
regulation of gtpase activityGO:00430871800.018
actin cytoskeleton organizationGO:00300362070.018
positive regulation of gtpase activityGO:00435471660.018
response to oxygen containing compoundGO:19017003690.018
negative regulation of developmental processGO:00510932470.018
spermatid differentiationGO:004851540.018
photoreceptor cell differentiationGO:004653020.018
circadian behaviorGO:004851220.018
neurological system processGO:00508771630.018
regulation of protein localizationGO:00328802960.018
nitrogen compound transportGO:00717051910.018
cardiac muscle cell contractionGO:008600340.018
limbic system developmentGO:002176130.018
regulation of ras protein signal transductionGO:00465781550.018
matingGO:000761810.018
secretionGO:00469032540.018
negative regulation of cell cycleGO:00457861930.018
neuron projection developmentGO:00311751060.018
cellular homeostasisGO:00197251960.018
negative regulation of axonogenesisGO:005077140.018
neuron developmentGO:00486661130.017
embryonic epithelial tube formationGO:000183840.017
cellular response to endogenous stimulusGO:00714953360.017
cation transmembrane transportGO:00986552380.017
defense responseGO:00069523150.017
tripartite regional subdivisionGO:000735120.017
regulation of peptidase activityGO:00525471800.017
rhythmic behaviorGO:000762220.017
cellular ion homeostasisGO:00068731680.017
mapk cascadeGO:00001652880.017
salivary gland morphogenesisGO:000743540.017
organophosphate biosynthetic processGO:00904071630.017
regulation of endopeptidase activityGO:00525481700.017
endomembrane system organizationGO:00102561960.017
regulation of meiotic cell cycleGO:005144540.017
regulation of neurotransmitter secretionGO:004692830.017
chemotaxisGO:00069351570.017
anterior posterior axis specification embryoGO:000859520.017
regulation of neural precursor cell proliferationGO:200017740.017
regulation of protein kinase activityGO:00458592890.017
regulation of growthGO:00400081650.017
carbohydrate metabolic processGO:00059752070.017
positive regulation of developmental processGO:00510943140.016
positive regulation of locomotionGO:00400171860.016
cerebral cortex cell migrationGO:002179530.016
regulation of cell developmentGO:00602841610.016
spermatid developmentGO:000728640.016
peripheral nervous system developmentGO:000742220.016
nerve developmentGO:002167540.016
regulation of protein maturationGO:19033171500.016
divalent metal ion transportGO:00708381520.016
growthGO:00400072020.016
cellular response to oxygen containing compoundGO:19017012760.016
covalent chromatin modificationGO:00165692540.016
compound eye developmentGO:004874910.016
positive regulation of apoptotic processGO:00430652460.016
innate immune responseGO:00450871780.016
peptidyl tyrosine phosphorylationGO:00181081700.016
positive regulation of programmed cell deathGO:00430682490.016
glycoprotein metabolic processGO:00091001100.016
taxisGO:00423301570.016
purine ribonucleoside monophosphate metabolic processGO:00091671860.016
meiosis iGO:000712740.016
regulation of protein transportGO:00512232130.016
posttranscriptional regulation of gene expressionGO:00106082130.016
cell cycle phase transitionGO:00447701730.016
positive regulation of transferase activityGO:00513472270.016
regulation of small gtpase mediated signal transductionGO:00510561560.016
chromatin modificationGO:00165682980.016
protein localization to membraneGO:00726571600.016
negative regulation of protein processingGO:00109551420.016
histone modificationGO:00165702510.016
response to axon injuryGO:004867810.015
regulation of establishment of protein localizationGO:00702012420.015
blood vessel morphogenesisGO:00485141620.015
secretion by cellGO:00329402260.015
lipid biosynthetic processGO:00086101770.015
sequestering of metal ionGO:0051238240.015
g protein coupled receptor signaling pathwayGO:00071862070.015
regulation of cell morphogenesisGO:00226041530.015
positive regulation of immune system processGO:00026842830.015
single organism carbohydrate metabolic processGO:00447231930.015
atp metabolic processGO:00460341760.015
visual behaviorGO:000763220.015
reactive oxygen species biosynthetic processGO:190340940.015
cellular cation homeostasisGO:00300031630.015
regulation of intracellular transportGO:00323861950.015
regulation of protein catabolic processGO:00421761550.015
enzyme linked receptor protein signaling pathwayGO:00071673030.015
negative regulation of organelle organizationGO:00106391260.015
endocytosisGO:00068971590.015
regulation of cell motilityGO:20001452990.015
meiotic chromosome segregationGO:004513240.015
positive regulation of kinase activityGO:00336742040.015
sequestering of calcium ionGO:0051208170.015
actin mediated cell contractionGO:0070252120.015
actin filament based movementGO:0030048170.015
circulatory system developmentGO:00723592620.015
negative regulation of intracellular signal transductionGO:19025321830.015
rna interferenceGO:001624640.015
protein oligomerizationGO:00512591730.015
cilium morphogenesisGO:0060271750.015
reactive nitrogen species metabolic processGO:200105730.015
neural tube formationGO:000184130.015
organ morphogenesisGO:00098871470.015
wnt signaling pathwayGO:00160551560.015
cilium organizationGO:0044782680.014
regulation of mitotic cell cycleGO:00073461890.014
syncytium formation by plasma membrane fusionGO:000076820.014
regulation of cell projection organizationGO:00313441070.014
ribonucleoside monophosphate metabolic processGO:00091611870.014
positive regulation of cellular component biogenesisGO:00440891580.014
positive regulation of cell proliferationGO:00082843010.014
positive regulation of cell motilityGO:20001471770.014
regulation of cytokine productionGO:00018172320.014
negative regulation of protein modification processGO:00314002000.014
sensory perception of smellGO:000760820.014
metencephalon developmentGO:002203720.014
cellular chemical homeostasisGO:00550821800.014
mitotic cell cycle phase transitionGO:00447721620.014
protein targetingGO:00066051870.014
positive regulation of protein kinase activityGO:00458601900.014
organonitrogen compound biosynthetic processGO:19015662000.014
forebrain generation of neuronsGO:002187230.014
establishment or maintenance of apical basal cell polarityGO:003508820.014
inner ear morphogenesisGO:004247240.014
single organismal cell cell adhesionGO:00163371480.014
regulation of ras gtpase activityGO:00323181280.014
purine nucleoside monophosphate metabolic processGO:00091261860.014
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.014
negative regulation of protein maturationGO:19033181420.014
regulation of actin filament based processGO:00329701410.014
nucleoside monophosphate metabolic processGO:00091231910.014
regulation of reactive oxygen species biosynthetic processGO:190342630.014
neuroblast proliferationGO:000740540.014
specification of organ identityGO:001009230.014
chromatin organizationGO:00063253510.014
vasculature developmentGO:00019441810.014
long term memoryGO:000761620.014
metal ion homeostasisGO:00550651690.014
regulation of ion transportGO:00432691890.014
negative regulation of proteolysisGO:00458611320.014
positive regulation of cell differentiationGO:00455972110.014
regulation of transcription from rna polymerase ii promoter mitoticGO:004602110.014
positive regulation of proteolysisGO:00458621420.014
mitotic nuclear divisionGO:00070671190.014
morphogenesis of a polarized epitheliumGO:000173830.014
regulation of dephosphorylationGO:0035303960.014
regulation of axon guidanceGO:190266730.014
regulation of secretion by cellGO:19035301770.013
heart formationGO:006091420.013
mitochondrion organizationGO:00070051560.013
response to external biotic stimulusGO:00432072610.013
positive regulation of reactive oxygen species biosynthetic processGO:190342820.013
angiogenesisGO:00015251470.013
divalent inorganic cation homeostasisGO:00725071360.013
regulation of protein processingGO:00706131500.013
axon cargo transportGO:000808820.013
cilium assemblyGO:0042384630.013
regulation of protein complex assemblyGO:00432541470.013
positive regulation of cellular component movementGO:00512721810.013
cell divisionGO:00513011680.013
regulation of vesicle mediated transportGO:00606271300.013
regulation of response to external stimulusGO:00321012220.013
regulation of membrane potentialGO:0042391950.013
positive regulation of organelle organizationGO:00106381950.013
calcium ion transportGO:00068161470.013
response to growth factorGO:00708482050.013
ameboidal type cell migrationGO:00016671350.013
positive regulation of ras gtpase activityGO:00323201170.013
oxidation reduction processGO:00551143960.013
organelle fissionGO:00482851490.013
cell morphogenesis involved in differentiationGO:00009041440.013
anion transportGO:00068201610.013
response to biotic stimulusGO:00096072760.013
startle responseGO:000196430.013
establishment or maintenance of bipolar cell polarityGO:006124520.013
melanin metabolic processGO:000658210.013
regulation of sequence specific dna binding transcription factor activityGO:00510902110.013
negative regulation of cell differentiationGO:00455961710.013
primary neural tube formationGO:001402030.013
epithelium developmentGO:00604292270.013
regulation of actin cytoskeleton organizationGO:00329561160.013
endosomal transportGO:00161971290.013
regulation of secretionGO:00510461940.013
cerebral cortex radially oriented cell migrationGO:002179910.013
rna processingGO:00063962550.013
spinal cord developmentGO:002151040.013
regulation of dna metabolic processGO:00510521530.013
reactive oxygen species metabolic processGO:0072593750.013
negative regulation of cell cycle processGO:00109481210.013
regulation of meiosisGO:004002030.013
glycoprotein biosynthetic processGO:0009101910.013
retinal ganglion cell axon guidanceGO:003129020.013
negative regulation of synaptic transmissionGO:005080520.013
epidermis morphogenesisGO:004873030.013
establishment of protein localization to organelleGO:00725941720.013
forelimb morphogenesisGO:003513640.013
cytokine productionGO:00018162470.012
somitogenesisGO:000175620.012
neuron projection regenerationGO:003110210.012
visual learningGO:000854210.012
nucleoside monophosphate catabolic processGO:00091251590.012
epithelial cell migrationGO:00106311190.012
negative regulation of phosphorylationGO:00423261740.012
regulation of cytoplasmic transportGO:19036491490.012
response to cytokineGO:00340972320.012
positive regulation of mapk cascadeGO:00434101900.012
plasma membrane organizationGO:00070091150.012
embryonic camera type eye developmentGO:003107620.012
response to nitrogen compoundGO:19016981840.012
developmental programmed cell deathGO:001062330.012
sensory perception of painGO:001923340.012
tube closureGO:006060630.012
purine nucleoside monophosphate catabolic processGO:00091281580.012
cell fate determinationGO:000170930.012
embryonic forelimb morphogenesisGO:003511540.012
establishment of nucleus localizationGO:004002310.012
tissue regenerationGO:004224630.012
neural tube closureGO:000184330.012
regulation of axon extension involved in axon guidanceGO:004884120.012
dna repairGO:00062811980.012
cerebellum developmentGO:002154920.012
regulation of transcription during mitosisGO:004589620.012
multi organism cellular processGO:00447641560.012
regulation of wnt signaling pathwayGO:00301111230.012
positive regulation of transcription from rna polymerase ii promoter during mitosisGO:004602210.012
blood vessel developmentGO:00015681720.012
nuclear transportGO:00511691790.012
establishment of protein localization to membraneGO:00901501210.012
regulation of apoptotic signaling pathwayGO:20012331750.012
forebrain neuron differentiationGO:002187930.012
cellular metal ion homeostasisGO:00068751460.012
divalent inorganic cation transportGO:00725111580.012
thymus developmentGO:004853830.012
response to other organismGO:00517072610.012
symbiosis encompassing mutualism through parasitismGO:00444031560.012
cell migration involved in gastrulationGO:004207410.012
axon regenerationGO:003110310.012
small molecule biosynthetic processGO:00442831570.012
nucleus localizationGO:005164710.012
epithelium migrationGO:00901321190.012
behaviorGO:00076101120.012
response to fungusGO:000962040.012
nucleocytoplasmic transportGO:00069131760.012
negative regulation of transportGO:00510511760.012
head developmentGO:00603221080.012
sex determinationGO:000753030.012
neuron remodelingGO:001632220.012
cellular response to cytokine stimulusGO:00713451810.012
protein acylationGO:00435431380.012
mammary gland morphogenesisGO:006044320.011
positive regulation of neural precursor cell proliferationGO:200017920.011
epithelial tube branching involved in lung morphogenesisGO:006044140.011
cellular response to growth factor stimulusGO:00713631970.011
glial cell migrationGO:000834740.011
organic hydroxy compound metabolic processGO:19016151470.011
stem cell divisionGO:001714520.011
synaptic vesicle endocytosisGO:004848820.011
negative regulation of locomotionGO:00400131180.011
neural tube patterningGO:002153220.011
cell substrate adhesionGO:00315891320.011
negative regulation of growthGO:0045926970.011
t cell differentiation in thymusGO:003307740.011
engulfment of apoptotic cellGO:004365220.011
male genitalia developmentGO:003053910.011
protein autophosphorylationGO:00467771230.011
positive regulation of cell migrationGO:00303351720.011
positive regulation of reactive oxygen species metabolic processGO:2000379240.011
response to organic cyclic compoundGO:00140702040.011
regulation of protein serine threonine kinase activityGO:00719001790.011
negative regulation of smoothened signaling pathwayGO:004587930.011
negative regulation of gliogenesisGO:001401430.011
regulation of homeostatic processGO:00328441210.011
striated muscle contractionGO:0006941520.011
axis elongationGO:000340140.011
hindlimb morphogenesisGO:003513720.011
organic anion transportGO:00157111030.011
canonical wnt signaling pathwayGO:00600701160.011
interspecies interaction between organismsGO:00444191560.011
response to radiationGO:00093141510.011
regulation of phosphatase activityGO:0010921810.011
regulation of multi organism processGO:00439001570.011
phospholipid metabolic processGO:0006644990.011
chromosome segregationGO:00070591140.011
response to woundingGO:00096111680.011
myoblast fusionGO:000752010.011
negative regulation of cell growthGO:0030308830.011
convergent extensionGO:006002610.011
hematopoietic or lymphoid organ developmentGO:00485341860.011
positive regulation of axon extensionGO:004577340.011
synaptic vesicle recyclingGO:003646530.011
calcium ion homeostasisGO:00550741220.011
scf dependent proteasomal ubiquitin dependent protein catabolic processGO:0031146150.011
positive regulation of protein transportGO:00512221350.011

FBXL2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
central nervous system diseaseDOID:3311860.031
nervous system diseaseDOID:8634310.031
sensory system diseaseDOID:00501552030.029
musculoskeletal system diseaseDOID:172230.027
disease of metabolismDOID:00146672950.022
eye diseaseDOID:56141490.022
eye and adnexa diseaseDOID:14921500.022
retinal diseaseDOID:56791180.018
cancerDOID:1621670.017
disease of cellular proliferationDOID:145661740.017
bone diseaseDOID:0080001880.017
connective tissue diseaseDOID:651090.017
neurodegenerative diseaseDOID:12891020.017
inherited metabolic disorderDOID:6552420.016
organ system cancerDOID:00506861640.016
immune system diseaseDOID:29141550.015
cardiovascular system diseaseDOID:12871060.014
brain diseaseDOID:936730.014
muscular diseaseDOID:00800001140.013
retinal degenerationDOID:8466890.013
myopathyDOID:4231040.013
muscle tissue diseaseDOID:661130.013
disease of mental healthDOID:150700.011