Homo sapiens

38 known processes

KLHDC5

kelch domain containing 5

(Aliases: MGC131714,Ctb9,KIAA1340)

KLHDC5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cell cycleGO:00517263930.134
cellular macromolecule catabolic processGO:00442653800.128
cellular protein catabolic processGO:00442572610.121
post embryonic developmentGO:000979120.109
multicellular organismal agingGO:001025930.100
modification dependent protein catabolic processGO:00199412090.098
ubiquitin dependent protein catabolic processGO:00065112060.088
proteolysis involved in cellular protein catabolic processGO:00516032440.081
protein modification by small protein conjugationGO:00324463420.080
protein catabolic processGO:00301633250.070
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.069
negative regulation of protein metabolic processGO:00512483910.067
regulation of cell cycle processGO:00105642660.065
cell morphogenesisGO:00009022960.059
determination of adult lifespanGO:000834020.057
cell developmentGO:00484683280.054
positive regulation of cellular component organizationGO:00511303760.052
negative regulation of cell deathGO:00605483450.052
purine ribonucleoside metabolic processGO:00461284370.049
tonic smooth muscle contractionGO:001482030.048
positive regulation of acrosome reactionGO:200034440.048
positive regulation of nucleotide catabolic processGO:00308131850.046
chemical homeostasisGO:00488783060.045
positive regulation of developmental processGO:00510943140.045
cell adhesionGO:00071553250.044
mitochondrion organizationGO:00070051560.044
regulation of cellular component movementGO:00512703340.042
regulation of secretion by cellGO:19035301770.041
distal tubule developmentGO:007201740.041
vesicle targeting rough er to cis golgiGO:004820720.040
regulation of protein catabolic processGO:00421761550.040
proteasomal protein catabolic processGO:00104981760.040
metal ion transportGO:00300012720.039
neuromuscular junction developmentGO:000752830.039
actin cytoskeleton organizationGO:00300362070.038
response to abiotic stimulusGO:00096283360.038
positive regulation of gtp catabolic processGO:00331261660.038
cation transportGO:00068123310.037
sodium ion transportGO:0006814610.037
ion homeostasisGO:00508012300.037
stem cell divisionGO:001714520.037
single organism membrane organizationGO:00448022680.037
positive regulation of phosphorylationGO:00423273940.036
regulation of cell motilityGO:20001452990.036
single organism cellular localizationGO:19025803320.036
ras protein signal transductionGO:0007265730.036
rho protein signal transductionGO:0007266260.036
positive regulation of catabolic processGO:00098963100.036
defense responseGO:00069523150.035
negative regulation of protein processingGO:00109551420.035
nucleoside triphosphate metabolic processGO:00091414220.035
biological adhesionGO:00226103310.035
response to cytokineGO:00340972320.035
positive regulation of cell differentiationGO:00455972110.034
rna interferenceGO:001624640.034
negative regulation of programmed cell deathGO:00430693210.034
regulation of cell growthGO:00015581350.034
protein k33 linked ubiquitinationGO:199039010.034
modification dependent macromolecule catabolic processGO:00436322120.033
negative regulation of intracellular signal transductionGO:19025321830.033
cell cycle phase transitionGO:00447701730.033
regulation of kinase activityGO:00435493140.033
actin filament based processGO:00300292240.033
renal sodium ion absorptionGO:007029420.032
regulation of proteolysisGO:00301622930.032
posttranscriptional regulation of gene expressionGO:00106082130.032
small gtpase mediated signal transductionGO:0007264780.032
system processGO:00030083490.031
purine nucleoside triphosphate catabolic processGO:00091463920.031
regulation of transferase activityGO:00513383550.031
ribonucleoside triphosphate metabolic processGO:00091994120.031
cell growthGO:00160491600.031
glycosyl compound catabolic processGO:19016584130.031
regulation of cellular protein catabolic processGO:1903362960.030
positive regulation of apoptotic processGO:00430652460.030
protein maturationGO:00516042330.030
ribonucleoside triphosphate catabolic processGO:00092033910.030
negative regulation of cellular protein metabolic processGO:00322693530.030
negative regulation of apoptotic processGO:00430663160.030
organelle fissionGO:00482851490.030
copii vesicle coatingGO:004820820.030
mitotic cell cycleGO:00002783260.029
negative regulation of phosphorus metabolic processGO:00105632670.029
purine nucleoside triphosphate metabolic processGO:00091444120.029
regulation of protein localizationGO:00328802960.029
response to oxidative stressGO:00069791210.028
cellular ketone metabolic processGO:0042180800.028
regulation of protein maturationGO:19033171500.028
segmentationGO:003528240.028
negative regulation of proteolysisGO:00458611320.028
membrane organizationGO:00610242920.028
positive regulation of purine nucleotide catabolic processGO:00331231850.028
purine containing compound catabolic processGO:00725234110.028
cellular response to dna damage stimulusGO:00069743790.028
mitotic cell cycle processGO:19030472860.028
ribonucleoside catabolic processGO:00424544060.027
regulation of purine nucleotide metabolic processGO:19005422640.027
regulation of proteasomal protein catabolic processGO:0061136870.027
negative regulation of catalytic activityGO:00430863350.027
negative regulation of cell cycle processGO:00109481210.027
purine ribonucleoside triphosphate catabolic processGO:00092073910.027
positive regulation of cellular catabolic processGO:00313312840.026
regulation of protein kinase activityGO:00458592890.026
regulation of cell cycle phase transitionGO:19019871260.026
nervous system developmentGO:00073992930.026
neurogenesisGO:00220081690.025
negative regulation of cell cycleGO:00457861930.025
negative regulation of protein maturationGO:19033181420.025
regenerationGO:003109940.025
protein ubiquitinationGO:00165673140.024
positive regulation of hydrolase activityGO:00513453310.024
immune responseGO:00069553070.024
positive regulation of purine nucleotide metabolic processGO:19005442270.024
guanosine containing compound metabolic processGO:19010682440.024
organophosphate catabolic processGO:00464344300.024
vesicle mediated transportGO:00161923710.024
positive regulation of transportGO:00510503360.024
protein localization to organelleGO:00333652800.024
female gamete generationGO:000729220.024
regulation of meiotic cell cycleGO:005144540.024
adult locomotory behaviorGO:000834410.024
regulation of establishment of protein localizationGO:00702012420.024
negative regulation of locomotionGO:00400131180.023
regulation of cell adhesionGO:00301551660.023
innate immune responseGO:00450871780.023
regulation of cellular response to stressGO:00801352440.023
regulation of cell differentiationGO:00455953930.023
positive regulation of organelle organizationGO:00106381950.023
positive regulation of gtpase activityGO:00435471660.023
regulation of cellular ketone metabolic processGO:0010565500.023
regulation of apoptotic signaling pathwayGO:20012331750.023
signal transduction by phosphorylationGO:00230142970.023
regulation of anatomical structure morphogenesisGO:00226032860.023
purine nucleotide catabolic processGO:00061954050.022
oxidation reduction processGO:00551143960.022
artery smooth muscle contractionGO:001482430.022
positive regulation of nucleoside metabolic processGO:00459791860.022
cell substrate adhesionGO:00315891320.022
regulation of cellular amine metabolic processGO:0033238110.022
negative regulation of protein phosphorylationGO:00019331400.022
intrinsic apoptotic signaling pathwayGO:00971931270.022
inorganic cation transmembrane transportGO:00986621940.021
cellular amino acid metabolic processGO:00065201160.021
growthGO:00400072020.021
purine ribonucleoside triphosphate metabolic processGO:00092054110.021
morphogenesis of embryonic epitheliumGO:001633140.021
cellular component morphogenesisGO:00329893140.021
purine nucleoside catabolic processGO:00061523980.021
cellular amine metabolic processGO:0044106410.021
oogenesisGO:004847720.021
protein processingGO:00164852260.021
regulation of ras protein signal transductionGO:00465781550.021
gtp metabolic processGO:00460392390.021
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787370.021
mitotic cell cycle phase transitionGO:00447721620.021
monovalent inorganic cation transportGO:00156721280.021
cytokinesisGO:0000910960.021
Human
positive regulation of secretion by cellGO:19035321080.021
regulation of protein transportGO:00512232130.020
endosomal transportGO:00161971290.020
blastocyst developmentGO:000182430.020
cell activationGO:00017752130.020
cellular protein complex assemblyGO:00436231880.020
cell projection organizationGO:00300302520.020
reactive oxygen species metabolic processGO:0072593750.020
organ morphogenesisGO:00098871470.020
nucleoside phosphate catabolic processGO:19012924120.020
regulation of nucleoside metabolic processGO:00091182090.019
positive regulation of programmed cell deathGO:00430682490.019
nucleoside catabolic processGO:00091644080.019
cell divisionGO:00513011680.019
Human
ion transmembrane transportGO:00342203380.019
regulation of multi organism processGO:00439001570.019
chromosome passenger complex localization to spindle midzoneGO:003585310.019
receptor guanylyl cyclase signaling pathwayGO:000716850.019
regulation of excitatory postsynaptic membrane potentialGO:006007910.019
regulation of nucleotide metabolic processGO:00061402690.019
response to radiationGO:00093141510.019
g protein coupled receptor signaling pathwayGO:00071862070.019
positive regulation of cellular component movementGO:00512721810.019
regulation of ras gtpase activityGO:00323181280.019
regulation of response to external stimulusGO:00321012220.018
regulation of protein processingGO:00706131500.018
positive regulation of immune system processGO:00026842830.018
negative regulation of protein modification processGO:00314002000.018
regulation of purine nucleotide catabolic processGO:00331212050.018
cellular chemical homeostasisGO:00550821800.018
positive regulation of kinase activityGO:00336742040.018
positive regulation of cell developmentGO:0010720920.018
proteasomal ubiquitin independent protein catabolic processGO:001049930.018
regulation of intracellular protein transportGO:00331571230.018
oocyte differentiationGO:000999420.018
nucleoside triphosphate catabolic processGO:00091433940.018
meiosis iGO:000712740.018
positive regulation of cell growthGO:0030307480.018
oocyte developmentGO:004859910.018
translationGO:00064121320.018
positive regulation of transferase activityGO:00513472270.018
positive regulation of cell proliferationGO:00082843010.018
intracellular protein transportGO:00068862700.018
regulation of mitotic cell cycleGO:00073461890.018
metal ion homeostasisGO:00550651690.018
positive regulation of cell deathGO:00109422630.018
positive regulation of cellular amine metabolic processGO:003324070.017
nucleotide catabolic processGO:00091664080.017
positive regulation of mapk cascadeGO:00434101900.017
chromatin organizationGO:00063253510.017
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.017
phototransductionGO:000760230.017
cellular response to cytokine stimulusGO:00713451810.017
purine ribonucleoside catabolic processGO:00461303980.017
negative regulation of hydrolase activityGO:00513461820.017
positive regulation of proteolysisGO:00458621420.017
positive regulation of cellular amino acid metabolic processGO:004576430.017
regulation of cellular amino acid metabolic processGO:000652160.017
regulation of growthGO:00400081650.017
regulation of mitotic cell cycle phase transitionGO:19019901180.017
negative regulation of cell proliferationGO:00082852280.017
protein targetingGO:00066051870.017
transmembrane transportGO:00550853990.017
amine metabolic processGO:0009308440.017
positive regulation of nucleotide metabolic processGO:00459812300.017
embryo developmentGO:00097901230.017
negative regulation of multicellular organismal processGO:00512413170.017
regulation of i kappab kinase nf kappab signalingGO:00431221620.017
blastoderm segmentationGO:000735020.016
regulation of cell migrationGO:00303342890.016
regulation of mapk cascadeGO:00434082620.016
apoptotic signaling pathwayGO:00971902680.016
regulation of gtpase activityGO:00430871800.016
negative regulation of cell growthGO:0030308830.016
neurological system processGO:00508771630.016
maintenance of locationGO:00512351120.016
golgi vesicle transportGO:0048193800.016
trophectodermal cell differentiationGO:000182930.016
purine ribonucleotide catabolic processGO:00091544040.016
motor neuron axon guidanceGO:000804520.016
negative regulation of phosphate metabolic processGO:00459362670.016
renal sodium ion transportGO:000309620.016
rhodopsin mediated signaling pathwayGO:001605610.016
negative regulation of mitotic cell cycle phase transitionGO:1901991850.016
morphogenesis of an epitheliumGO:0002009600.015
protein oligomerizationGO:00512591730.015
reactive oxygen species biosynthetic processGO:190340940.015
negative regulation of phosphorylationGO:00423261740.015
wnt signaling pathwayGO:00160551560.015
regulation of locomotionGO:00400123290.015
metencephalon developmentGO:002203720.015
negative regulation of cell cycle phase transitionGO:1901988890.015
gtp catabolic processGO:00061842370.015
positive regulation of reactive oxygen species biosynthetic processGO:190342820.015
response to biotic stimulusGO:00096072760.015
lipid metabolic processGO:00066293810.015
regulation of protein serine threonine kinase activityGO:00719001790.015
cytoplasmic transportGO:00164823790.015
regulation of intracellular transportGO:00323861950.015
regulation of vesicle mediated transportGO:00606271300.015
cation transmembrane transportGO:00986552380.015
ribonucleotide catabolic processGO:00092614050.015
tube developmentGO:00352951250.015
response to inorganic substanceGO:00100351270.015
regulation of cell morphogenesisGO:00226041530.015
carbohydrate derivative biosynthetic processGO:19011372070.015
response to oxygen levelsGO:00704821000.015
cellular divalent inorganic cation homeostasisGO:00725031280.015
regulation of nucleotide catabolic processGO:00308112050.015
anatomical structure formation involved in morphogenesisGO:00486462840.014
inorganic ion transmembrane transportGO:00986602310.014
macromolecule methylationGO:0043414970.014
regulation of reactive oxygen species biosynthetic processGO:190342630.014
negative regulation of cellular component organizationGO:00511292350.014
startle responseGO:000196430.014
positive regulation of locomotionGO:00400171860.014
positive regulation of response to external stimulusGO:0032103880.014
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.014
cellular lipid metabolic processGO:00442553030.014
peptidyl lysine modificationGO:00182051440.014
cell cycle checkpointGO:00000751170.014
positive regulation of cell adhesionGO:0045785840.014
negative regulation of developmental processGO:00510932470.014
hindbrain developmentGO:003090230.014
nucleus organizationGO:0006997280.014
regulation of cytoskeleton organizationGO:00514931770.014
blastocyst formationGO:000182530.014
regulation of secretionGO:00510461940.014
regulation of postsynaptic membrane potentialGO:006007810.014
secretion by cellGO:00329402260.014
mrna metabolic processGO:00160711750.014
positive regulation of protein kinase activityGO:00458601900.014
regulation of small gtpase mediated signal transductionGO:00510561560.014
guanosine containing compound catabolic processGO:19010692390.014
stress activated protein kinase signaling cascadeGO:0031098940.014
response to external biotic stimulusGO:00432072610.014
positive regulation of protein catabolic processGO:0045732750.014
positive regulation of protein phosphorylationGO:00019343130.014
regulation of ion transportGO:00432691890.014
associative learningGO:000830610.014
regulation of synaptic plasticityGO:004816730.014
negative regulation of growthGO:0045926970.014
memoryGO:000761330.014
cellular response to external stimulusGO:00714961110.014
ribonucleoside monophosphate metabolic processGO:00091611870.014
organelle assemblyGO:00709251760.014
locomotory behaviorGO:000762610.013
syncytium formation by plasma membrane fusionGO:000076820.013
negative regulation of cellular protein catabolic processGO:1903363380.013
peripheral nervous system developmentGO:000742220.013
nuclear divisionGO:00002801280.013
response to fungusGO:000962040.013
response to oxygen containing compoundGO:19017003690.013
positive regulation of nfat protein import into nucleusGO:005153330.013
cerebellum developmentGO:002154920.013
generation of neuronsGO:00486991520.013
positive regulation of secretionGO:00510471160.013
muscle system processGO:0003012810.013
negative regulation of synaptic transmissionGO:005080520.013
anterior posterior axis specification embryoGO:000859520.013
methylationGO:00322591060.013
nucleoside monophosphate metabolic processGO:00091231910.013
negative regulation of immune system processGO:00026831360.013
convergent extensionGO:006002610.013
mapk cascadeGO:00001652880.013
leukocyte migrationGO:00509001070.013
regulation of peptidase activityGO:00525471800.013
protein monoubiquitinationGO:0006513390.013
protein homooligomerizationGO:00512601000.013
cytokine productionGO:00018162470.013
thymus developmentGO:004853830.013
cellular response to nutrient levelsGO:0031669690.013
canonical wnt signaling pathway involved in mesenchymal stem cell differentiationGO:004433820.013
negative regulation of axonogenesisGO:005077140.012
visual behaviorGO:000763220.012
negative regulation of protein kinase activityGO:0006469980.012
regulation of mitochondrion organizationGO:0010821540.012
positive regulation of neurogenesisGO:0050769490.012
second messenger mediated signalingGO:0019932780.012
defense response to other organismGO:00985421290.012
divalent inorganic cation homeostasisGO:00725071360.012
regulation of protein stabilityGO:0031647870.012
lipid biosynthetic processGO:00086101770.012
tripartite regional subdivisionGO:000735120.012
multi organism cellular processGO:00447641560.012
negative regulation of catabolic processGO:00098951040.012
positive regulation of protein polymerizationGO:0032273450.012
protein stabilizationGO:0050821640.012
canonical wnt signaling pathway involved in osteoblast differentiationGO:004433920.012
secretionGO:00469032540.012
regulation of gtp catabolic processGO:00331241800.012
stress activated mapk cascadeGO:0051403930.012
protein localization to nucleusGO:00345041360.012
t cell differentiation in thymusGO:003307740.012
purine ribonucleoside monophosphate metabolic processGO:00091671860.012
tissue morphogenesisGO:0048729960.012
cellular ion homeostasisGO:00068731680.012
visual learningGO:000854210.012
leukocyte activationGO:00453211640.012
reproductive processGO:00224141060.012
epithelium developmentGO:00604292270.012
somatic stem cell divisionGO:004810310.012
spermatid developmentGO:000728640.012
branch elongation of an epitheliumGO:006060230.012
positive regulation of cell motilityGO:20001471770.012
neural tube formationGO:000184130.012
cytokine mediated signaling pathwayGO:00192211090.011
spermatid differentiationGO:004851540.011
regulation of protein modification by small protein conjugation or removalGO:19033201070.011
dna damage checkpointGO:0000077680.011
response to hormoneGO:00097251750.011
limbic system developmentGO:002176130.011
nuclear importGO:00511701060.011
response to bacteriumGO:00096171440.011
embryonic epithelial tube formationGO:000183840.011
regulation of actin filament based processGO:00329701410.011
positive regulation of cell cycleGO:00457871400.011
positive regulation of cellular component biogenesisGO:00440891580.011
positive regulation of reactive oxygen species metabolic processGO:2000379240.011
non canonical wnt signaling pathway via mapk cascadeGO:003803040.011
positive regulation of cell morphogenesis involved in differentiationGO:0010770500.011
positive regulation of behaviorGO:0048520600.011
rna splicingGO:00083801310.011
regulation of cytoplasmic transportGO:19036491490.011
mitotic cell cycle checkpointGO:0007093680.011
regulation of cytokinesisGO:0032465450.011
chemotaxisGO:00069351570.011
ectoderm developmentGO:000739830.011
regulation of cellular response to growth factor stimulusGO:0090287760.011
apoptotic mitochondrial changesGO:0008637570.011
regulation of cell divisionGO:00513021160.011
cell projection morphogenesisGO:00488581290.011
cell cycle g1 s phase transitionGO:0044843800.011
negative regulation of cellular catabolic processGO:0031330830.011
negative regulation of response to external stimulusGO:0032102830.011
single organism cell adhesionGO:00986021790.011
peptidyl tyrosine phosphorylationGO:00181081700.011
anterior posterior axis specificationGO:000994820.011
regulation of immune responseGO:00507762010.011
regulation of membrane potentialGO:0042391950.011
protein acetylationGO:00064731160.011
regulation of cytokine productionGO:00018172320.011
microtubule based processGO:00070172100.011
regulation of reactive oxygen species metabolic processGO:2000377410.011
positive regulation of cell migrationGO:00303351720.011
regulation of meiosisGO:004002030.011
multicellular organismal response to stressGO:003355510.011
neuron differentiationGO:00301821380.011
negative regulation of multi organism processGO:0043901920.011
cellular response to extracellular stimulusGO:0031668720.010
purine containing compound biosynthetic processGO:0072522880.010
phospholipid metabolic processGO:0006644990.010
regulation of nervous system developmentGO:0051960880.010
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.010
negative regulation of transferase activityGO:00513481240.010
hippocampus developmentGO:002176610.010
cation homeostasisGO:00550801890.010
regulation of cell substrate adhesionGO:0010810680.010
cellular response to potassium ionGO:003586550.010
defense response to fungusGO:005083240.010
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.010
neuroblast proliferationGO:000740540.010
muscle contractionGO:0006936730.010
response to light stimulusGO:0009416870.010
epithelial cell proliferationGO:00506731280.010
distal tubule morphogenesisGO:007215630.010
negative regulation of cellular amino acid metabolic processGO:004576320.010
cellular response to abiotic stimulusGO:00712141170.010
regulation of protein ubiquitinationGO:0031396950.010
carbohydrate metabolic processGO:00059752070.010
response to metal ionGO:0010038840.010

KLHDC5 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
central nervous system diseaseDOID:3311860.027
nervous system diseaseDOID:8634310.027
musculoskeletal system diseaseDOID:172230.024
muscular diseaseDOID:00800001140.024
myopathyDOID:4231040.019
muscle tissue diseaseDOID:661130.019
muscular dystrophyDOID:9884510.019
disease of cellular proliferationDOID:145661740.012
organ system cancerDOID:00506861640.012
cancerDOID:1621670.012
neurodegenerative diseaseDOID:12891020.011
brain diseaseDOID:936730.011
urinary system diseaseDOID:18400.011
disease of metabolismDOID:00146672950.010