Homo sapiens

27 known processes

POLK

polymerase (DNA directed) kappa

(Aliases: DINP,POLQ,DINB1)

POLK biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ribonucleotide catabolic processGO:00092614050.124
dna repairGO:00062811980.121
cellular response to dna damage stimulusGO:00069743790.096
nucleoside triphosphate catabolic processGO:00091433940.096
organophosphate catabolic processGO:00464344300.092
purine nucleoside triphosphate catabolic processGO:00091463920.089
purine nucleoside catabolic processGO:00061523980.089
double strand break repair via homologous recombinationGO:0000724500.086
regulation of dna metabolic processGO:00510521530.086
nucleoside triphosphate metabolic processGO:00091414220.079
purine nucleotide catabolic processGO:00061954050.078
ribonucleoside triphosphate metabolic processGO:00091994120.073
nucleoside catabolic processGO:00091644080.071
purine ribonucleoside metabolic processGO:00461284370.071
double strand break repairGO:00063021010.071
purine ribonucleoside triphosphate metabolic processGO:00092054110.067
response to abiotic stimulusGO:00096283360.066
positive regulation of hydrolase activityGO:00513453310.063
recombinational repairGO:0000725500.063
purine ribonucleotide catabolic processGO:00091544040.062
nucleoside phosphate catabolic processGO:19012924120.062
purine containing compound catabolic processGO:00725234110.061
gtp metabolic processGO:00460392390.058
purine ribonucleoside triphosphate catabolic processGO:00092073910.056
guanosine containing compound catabolic processGO:19010692390.056
ribonucleoside triphosphate catabolic processGO:00092033910.056
regulation of nucleotide catabolic processGO:00308112050.054
glycosyl compound catabolic processGO:19016584130.054
regulation of cellular response to stressGO:00801352440.053
vesicle mediated transportGO:00161923710.052
regulation of purine nucleotide catabolic processGO:00331212050.052
cellular macromolecule catabolic processGO:00442653800.051
regulation of gtpase activityGO:00430871800.050
postreplication repairGO:0006301120.049
purine ribonucleoside catabolic processGO:00461303980.048
purine nucleoside triphosphate metabolic processGO:00091444120.046
guanosine containing compound metabolic processGO:19010682440.045
nucleotide catabolic processGO:00091664080.045
positive regulation of nucleotide catabolic processGO:00308131850.044
response to uvGO:0009411730.044
regulation of gtp catabolic processGO:00331241800.044
translesion synthesisGO:001998580.043
gtp catabolic processGO:00061842370.043
dna recombinationGO:0006310770.043
regulation of purine nucleotide metabolic processGO:19005422640.043
regulation of nucleotide metabolic processGO:00061402690.041
positive regulation of cellular catabolic processGO:00313312840.039
positive regulation of catabolic processGO:00098963100.039
response to radiationGO:00093141510.039
positive regulation of gtpase activityGO:00435471660.038
positive regulation of nucleoside metabolic processGO:00459791860.038
negative regulation of cell deathGO:00605483450.038
cellular amino acid metabolic processGO:00065201160.036
regulation of nucleoside metabolic processGO:00091182090.035
amine metabolic processGO:0009308440.035
positive regulation of purine nucleotide catabolic processGO:00331231850.033
positive regulation of purine nucleotide metabolic processGO:19005442270.033
dna biosynthetic processGO:0071897400.033
negative regulation of programmed cell deathGO:00430693210.033
post embryonic developmentGO:000979120.032
cytoplasmic transportGO:00164823790.031
ribonucleoside catabolic processGO:00424544060.029
intracellular protein transportGO:00068862700.028
response to light stimulusGO:0009416870.028
regulation of pathway restricted smad protein phosphorylationGO:0060393340.028
negative regulation of phosphorus metabolic processGO:00105632670.027
regulation of double strand break repair via homologous recombinationGO:0010569110.027
positive regulation of gtp catabolic processGO:00331261660.027
cellular ketone metabolic processGO:0042180800.026
positive regulation of nucleotide metabolic processGO:00459812300.025
negative regulation of apoptotic processGO:00430663160.025
immune responseGO:00069553070.025
multicellular organismal agingGO:001025930.025
regulation of cell cycle processGO:00105642660.023
hematopoietic or lymphoid organ developmentGO:00485341860.023
determination of adult lifespanGO:000834020.023
negative regulation of catalytic activityGO:00430863350.022
single organism membrane organizationGO:00448022680.022
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.022
protein ubiquitinationGO:00165673140.022
regulation of cell differentiationGO:00455953930.021
intrinsic apoptotic signaling pathwayGO:00971931270.021
membrane organizationGO:00610242920.021
nucleic acid phosphodiester bond hydrolysisGO:00903051020.021
transforming growth factor beta receptor signaling pathwayGO:0007179760.021
apoptotic signaling pathwayGO:00971902680.020
regulation of cell motilityGO:20001452990.020
regulation of locomotionGO:00400123290.020
regulation of cellular amino acid metabolic processGO:000652160.020
negative regulation of phosphate metabolic processGO:00459362670.020
positive regulation of cellular amino acid metabolic processGO:004576430.020
sex determinationGO:000753030.020
regulation of dna recombinationGO:0000018230.020
regulation of cellular component movementGO:00512703340.020
regulation of response to dna damage stimulusGO:2001020940.019
anatomical structure homeostasisGO:00602491000.019
ion homeostasisGO:00508012300.019
immune system developmentGO:00025201950.019
regulation of cellular component biogenesisGO:00440872810.018
female gamete generationGO:000729220.018
cellular protein catabolic processGO:00442572610.018
metal ion transportGO:00300012720.018
chemical homeostasisGO:00488783060.018
regulation of protein localizationGO:00328802960.018
nuclear transportGO:00511691790.018
protein localization to organelleGO:00333652800.018
purine ribonucleoside monophosphate metabolic processGO:00091671860.017
regulation of anatomical structure morphogenesisGO:00226032860.017
regulation of proteolysisGO:00301622930.017
somatic recombination of immunoglobulin gene segmentsGO:001644740.017
regulation of cellular ketone metabolic processGO:0010565500.017
proteolysis involved in cellular protein catabolic processGO:00516032440.017
actin cytoskeleton organizationGO:00300362070.017
positive regulation of cellular amine metabolic processGO:003324070.017
regulation of establishment of protein localizationGO:00702012420.017
regulation of dna repairGO:0006282470.016
cellular amine metabolic processGO:0044106410.016
negative regulation of cellular amino acid metabolic processGO:004576320.016
endocytosisGO:00068971590.016
cellular lipid metabolic processGO:00442553030.016
negative regulation of phosphorylationGO:00423261740.016
protein catabolic processGO:00301633250.016
negative regulation of cellular protein metabolic processGO:00322693530.016
positive regulation of cell motilityGO:20001471770.016
mitotic cell cycleGO:00002783260.016
single organism cellular localizationGO:19025803320.016
atp metabolic processGO:00460341760.016
maintenance of locationGO:00512351120.015
nitrogen compound transportGO:00717051910.015
negative regulation of protein metabolic processGO:00512483910.015
posttranscriptional regulation of gene expressionGO:00106082130.015
cellular response to transforming growth factor beta stimulusGO:0071560940.015
oogenesisGO:004847720.015
meiosis iGO:000712740.015
organelle assemblyGO:00709251760.015
cell adhesionGO:00071553250.015
mitochondrion organizationGO:00070051560.015
regulation of cytokine productionGO:00018172320.015
rab protein signal transductionGO:003248240.015
regulation of cellular amine metabolic processGO:0033238110.015
positive regulation of cellular component biogenesisGO:00440891580.015
positive regulation of transportGO:00510503360.015
ras protein signal transductionGO:0007265730.015
regulation of double strand break repairGO:2000779220.015
nucleoside monophosphate metabolic processGO:00091231910.015
cellular macromolecular complex assemblyGO:00346223240.014
negative regulation of cellular amine metabolic processGO:003323930.014
positive regulation of programmed cell deathGO:00430682490.014
protein modification by small protein conjugationGO:00324463420.014
mitotic cell cycle processGO:19030472860.014
modification dependent macromolecule catabolic processGO:00436322120.014
regulation of protein complex assemblyGO:00432541470.014
negative regulation of protein modification processGO:00314002000.014
positive regulation of cell differentiationGO:00455972110.014
cellular response to endogenous stimulusGO:00714953360.014
regulation of transferase activityGO:00513383550.014
chromatin organizationGO:00063253510.014
chromatin modificationGO:00165682980.014
lipid metabolic processGO:00066293810.013
divalent inorganic cation transportGO:00725111580.013
regenerationGO:003109940.013
negative regulation of protein phosphorylationGO:00019331400.013
lung alveolus developmentGO:004828640.013
positive regulation of ras gtpase activityGO:00323201170.013
proteasomal protein catabolic processGO:00104981760.013
negative regulation of intracellular signal transductionGO:19025321830.013
regulation of cell migrationGO:00303342890.013
negative regulation of cell proliferationGO:00082852280.013
sequestering of metal ionGO:0051238240.013
locomotory behaviorGO:000762610.013
memoryGO:000761330.013
negative regulation of cell cycleGO:00457861930.013
cellular homeostasisGO:00197251960.013
regulation of protein transportGO:00512232130.013
positive regulation of immune system processGO:00026842830.013
histone modificationGO:00165702510.013
cation transportGO:00068123310.013
inner ear morphogenesisGO:004247240.013
blastoderm segmentationGO:000735020.013
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.013
regulation of kinase activityGO:00435493140.012
embryo developmentGO:00097901230.012
positive regulation of proteolysisGO:00458621420.012
actin filament based processGO:00300292240.012
regulation of protein catabolic processGO:00421761550.012
positive regulation of apoptotic processGO:00430652460.012
hemopoiesisGO:00300971800.012
organelle fissionGO:00482851490.012
protein localization to membraneGO:00726571600.012
cellular cation homeostasisGO:00300031630.012
regulation of mitotic cell cycleGO:00073461890.012
pathway restricted smad protein phosphorylationGO:0060389380.012
receptor mediated endocytosisGO:0006898840.012
response to growth factorGO:00708482050.012
rna interferenceGO:001624640.012
regulation of intracellular transportGO:00323861950.012
biological adhesionGO:00226103310.011
endosomal transportGO:00161971290.011
positive regulation of rab gtpase activityGO:0032851390.011
rho protein signal transductionGO:0007266260.011
hindbrain developmentGO:003090230.011
positive regulation of cellular component movementGO:00512721810.011
segmentationGO:003528240.011
regulation of dephosphorylationGO:0035303960.011
regulation of secretionGO:00510461940.011
innate immune responseGO:00450871780.011
cellular component morphogenesisGO:00329893140.011
endomembrane system organizationGO:00102561960.011
regulation of intracellular protein transportGO:00331571230.011
cell part morphogenesisGO:00329901370.011
regulation of ras gtpase activityGO:00323181280.011
response to metal ionGO:0010038840.011
cell morphogenesisGO:00009022960.011
organophosphate biosynthetic processGO:00904071630.011
amide transportGO:0042886760.011
small gtpase mediated signal transductionGO:0007264780.011
positive regulation of cell migrationGO:00303351720.011
negative regulation of transportGO:00510511760.011
autophagyGO:0006914880.011
regulation of cell cycleGO:00517263930.011
cation transmembrane transportGO:00986552380.011
cell projection organizationGO:00300302520.011
system processGO:00030083490.011
regulation of protein kinase activityGO:00458592890.011
purine ribonucleoside monophosphate catabolic processGO:00091691580.011
protein import into nucleusGO:00066061040.011
negative regulation of cellular component organizationGO:00511292350.010
establishment of protein localization to organelleGO:00725941720.010
t cell differentiation in thymusGO:003307740.010
sequestering of calcium ionGO:0051208170.010
nucleocytoplasmic transportGO:00069131760.010
adult locomotory behaviorGO:000834410.010
response to woundingGO:00096111680.010
regulation of cell morphogenesisGO:00226041530.010
modification dependent protein catabolic processGO:00199412090.010
cellular metal ion homeostasisGO:00068751460.010
protein autophosphorylationGO:00467771230.010
defense responseGO:00069523150.010

POLK disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.021
musculoskeletal system diseaseDOID:172230.018
cancerDOID:1621670.015
sensory system diseaseDOID:00501552030.015
eye diseaseDOID:56141490.015
nervous system diseaseDOID:8634310.015
eye and adnexa diseaseDOID:14921500.015
organ system cancerDOID:00506861640.014
central nervous system diseaseDOID:3311860.013
immune system diseaseDOID:29141550.012
retinal diseaseDOID:56791180.011
connective tissue diseaseDOID:651090.011
muscular diseaseDOID:00800001140.011