Homo sapiens

97 known processes

ASXL2

additional sex combs like 2 (Drosophila)

(Aliases: DKFZp686C1968,KIAA1685,FLJ10898,ASXH2)

ASXL2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to histamineGO:007142030.160
regulation of cell cycleGO:00517263930.108
small gtpase mediated signal transductionGO:0007264780.094
ras protein signal transductionGO:0007265730.072
determination of adult lifespanGO:000834020.066
vesicle mediated transportGO:00161923710.064
regulation of small gtpase mediated signal transductionGO:00510561560.063
regulation of cell cycle processGO:00105642660.060
multicellular organismal agingGO:001025930.058
post embryonic developmentGO:000979120.057
growthGO:00400072020.056
phosphorylation of rna polymerase ii c terminal domainGO:007081630.055
negative regulation of protein metabolic processGO:00512483910.055
protein modification by small protein conjugationGO:00324463420.054
nervous system developmentGO:00073992930.051
regulation of transferase activityGO:00513383550.050
signal transduction by phosphorylationGO:00230142970.050
positive regulation of phosphorylationGO:00423273940.050
regulation of anatomical structure morphogenesisGO:00226032860.049
purine ribonucleoside triphosphate metabolic processGO:00092054110.049
cellular amino acid metabolic processGO:00065201160.048
inorganic ion transmembrane transportGO:00986602310.048
purine ribonucleoside catabolic processGO:00461303980.044
regulation of proteolysisGO:00301622930.044
negative regulation of hydrolase activityGO:00513461820.044
cell morphogenesisGO:00009022960.043
mitotic cell cycleGO:00002783260.042
purine ribonucleoside metabolic processGO:00461284370.042
actin filament based processGO:00300292240.042
nucleoside triphosphate catabolic processGO:00091433940.041
cellular macromolecule catabolic processGO:00442653800.041
negative regulation of cellular protein metabolic processGO:00322693530.040
cellular component morphogenesisGO:00329893140.040
positive regulation of mapk cascadeGO:00434101900.040
regulation of mapk cascadeGO:00434082620.040
nucleoside phosphate catabolic processGO:19012924120.040
regulation of kinase activityGO:00435493140.040
regulation of cell differentiationGO:00455953930.039
ribonucleoside triphosphate metabolic processGO:00091994120.039
purine nucleoside triphosphate metabolic processGO:00091444120.038
cellular response to organic cyclic compoundGO:00714071270.038
protein catabolic processGO:00301633250.038
nucleoside catabolic processGO:00091644080.038
positive regulation of cellular component organizationGO:00511303760.038
Mouse
cellular ketone metabolic processGO:0042180800.038
cell divisionGO:00513011680.037
regulation of proteasomal protein catabolic processGO:0061136870.037
regulation of cellular amino acid metabolic processGO:000652160.037
segmentationGO:003528240.036
purine nucleotide catabolic processGO:00061954050.036
amine metabolic processGO:0009308440.036
purine containing compound catabolic processGO:00725234110.036
cellular protein catabolic processGO:00442572610.036
cell growthGO:00160491600.035
chromatin modificationGO:00165682980.035
Human Mouse
regulation of protein serine threonine kinase activityGO:00719001790.035
metal ion transportGO:00300012720.034
purine ribonucleoside triphosphate catabolic processGO:00092073910.034
purine nucleoside triphosphate catabolic processGO:00091463920.034
mapk cascadeGO:00001652880.034
cytokinesisGO:0000910960.034
cellular response to endogenous stimulusGO:00714953360.033
ribonucleoside catabolic processGO:00424544060.033
regulation of protein kinase activityGO:00458592890.033
organophosphate catabolic processGO:00464344300.033
ribonucleotide catabolic processGO:00092614050.033
cell projection organizationGO:00300302520.032
nucleoside triphosphate metabolic processGO:00091414220.032
glycosyl compound catabolic processGO:19016584130.032
regulation of ras protein signal transductionGO:00465781550.032
regulation of cell morphogenesisGO:00226041530.032
compound eye developmentGO:004874910.032
positive regulation of catabolic processGO:00098963100.032
protein autophosphorylationGO:00467771230.032
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.031
Mouse
cellular amine metabolic processGO:0044106410.031
regulation of cellular amine metabolic processGO:0033238110.031
metal ion homeostasisGO:00550651690.031
purine nucleoside catabolic processGO:00061523980.031
nucleotide catabolic processGO:00091664080.031
locomotory behaviorGO:000762610.031
positive regulation of cellular amino acid metabolic processGO:004576430.031
mitotic cell cycle phase transitionGO:00447721620.031
positive regulation of cell cycle processGO:00900681060.030
protein ubiquitinationGO:00165673140.030
cell cycle phase transitionGO:00447701730.030
immune responseGO:00069553070.030
secretionGO:00469032540.029
regulation of cellular component biogenesisGO:00440872810.029
system processGO:00030083490.029
purine ribonucleotide catabolic processGO:00091544040.028
negative regulation of protein processingGO:00109551420.028
neurological system processGO:00508771630.028
cellular macromolecular complex assemblyGO:00346223240.028
positive regulation of cellular catabolic processGO:00313312840.028
innate immune responseGO:00450871780.028
negative regulation of programmed cell deathGO:00430693210.027
spermatid differentiationGO:004851540.027
embryonic camera type eye developmentGO:003107620.027
regulation of cytoskeleton organizationGO:00514931770.027
ubiquitin dependent protein catabolic processGO:00065112060.027
regulation of cellular ketone metabolic processGO:0010565500.027
mitotic cell cycle processGO:19030472860.027
protein processingGO:00164852260.027
regulation of protein localizationGO:00328802960.027
enzyme linked receptor protein signaling pathwayGO:00071673030.027
erk1 and erk2 cascadeGO:00703711040.026
hematopoietic or lymphoid organ developmentGO:00485341860.026
Mouse
histone modificationGO:00165702510.026
Human Mouse
anterior posterior axis specificationGO:000994820.026
ribonucleoside triphosphate catabolic processGO:00092033910.026
morphogenesis of embryonic epitheliumGO:001633140.025
cellular divalent inorganic cation homeostasisGO:00725031280.025
response to woundingGO:00096111680.025
cellular response to dna damage stimulusGO:00069743790.025
actin filament based movementGO:0030048170.025
positive regulation of cellular amine metabolic processGO:003324070.025
regulation of nucleotide metabolic processGO:00061402690.025
regulation of purine nucleotide metabolic processGO:19005422640.024
negative regulation of apoptotic processGO:00430663160.024
chemical homeostasisGO:00488783060.024
defense responseGO:00069523150.024
cellular response to oxygen containing compoundGO:19017012760.024
positive regulation of transportGO:00510503360.024
actin cytoskeleton organizationGO:00300362070.024
response to organic cyclic compoundGO:00140702040.023
proteolysis involved in cellular protein catabolic processGO:00516032440.023
transmembrane transportGO:00550853990.023
cellular calcium ion homeostasisGO:00068741170.023
regulation of cell cycle phase transitionGO:19019871260.023
maintenance of locationGO:00512351120.023
positive regulation of organelle organizationGO:00106381950.023
Mouse
regulation of nucleotide catabolic processGO:00308112050.023
regulation of meiotic cell cycleGO:005144540.023
cation transmembrane transportGO:00986552380.023
proteasomal protein catabolic processGO:00104981760.023
cell projection assemblyGO:00300311260.023
calcium ion homeostasisGO:00550741220.023
neuron differentiationGO:00301821380.023
primary neural tube formationGO:001402030.023
cytoplasmic transportGO:00164823790.022
apoptotic signaling pathwayGO:00971902680.022
embryonic eye morphogenesisGO:004804820.022
negative regulation of cellular component organizationGO:00511292350.022
tripartite regional subdivisionGO:000735120.022
ion homeostasisGO:00508012300.022
positive regulation of nucleotide metabolic processGO:00459812300.022
cellular metal ion homeostasisGO:00068751460.022
response to growth factorGO:00708482050.022
protein maturationGO:00516042330.022
regulation of nucleoside metabolic processGO:00091182090.022
wnt signaling pathwayGO:00160551560.022
modification dependent protein catabolic processGO:00199412090.022
microtubule based processGO:00070172100.022
biological adhesionGO:00226103310.022
chromatin organizationGO:00063253510.022
Human Mouse
regulation of mitotic cell cycleGO:00073461890.022
negative regulation of catalytic activityGO:00430863350.021
regulation of protein catabolic processGO:00421761550.021
atp metabolic processGO:00460341760.021
cytokine productionGO:00018162470.021
regulation of cellular protein catabolic processGO:1903362960.021
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.021
regulation of mitotic cell cycle phase transitionGO:19019901180.021
neuromuscular junction developmentGO:000752830.021
negative regulation of protein maturationGO:19033181420.021
meiosis iGO:000712740.021
cation homeostasisGO:00550801890.021
memoryGO:000761330.021
ion transmembrane transportGO:00342203380.021
positive regulation of store operated calcium channel activityGO:190134140.020
protein localization to organelleGO:00333652800.020
cation transportGO:00068123310.020
negative regulation of protein modification processGO:00314002000.020
nucleoside monophosphate metabolic processGO:00091231910.020
negative regulation of cell deathGO:00605483450.020
secretion by cellGO:00329402260.020
calcium ion transportGO:00068161470.020
cell projection morphogenesisGO:00488581290.019
cellular homeostasisGO:00197251960.019
single organism reproductive processGO:0044702980.019
embryo developmentGO:00097901230.019
Mouse
embryonic camera type eye morphogenesisGO:004859620.019
rna processingGO:00063962550.019
positive regulation of immune system processGO:00026842830.019
Mouse
neuron projection developmentGO:00311751060.019
female gamete generationGO:000729220.019
neural tube formationGO:000184130.019
dephosphorylationGO:00163112090.019
inorganic cation transmembrane transportGO:00986621940.018
membrane organizationGO:00610242920.018
positive regulation of erk1 and erk2 cascadeGO:0070374750.018
lung alveolus developmentGO:004828640.018
regulation of actin filament based processGO:00329701410.018
negative regulation of phosphate metabolic processGO:00459362670.018
anatomical structure formation involved in morphogenesisGO:00486462840.018
modification dependent macromolecule catabolic processGO:00436322120.018
neurogenesisGO:00220081690.018
regulation of calcium ion transportGO:0051924790.018
cellular ion homeostasisGO:00068731680.018
rho protein signal transductionGO:0007266260.018
regulation of protein maturationGO:19033171500.018
spermatid developmentGO:000728640.018
gtp metabolic processGO:00460392390.018
negative regulation of intracellular signal transductionGO:19025321830.018
regenerationGO:003109940.018
negative regulation of phosphorus metabolic processGO:00105632670.018
positive regulation of gtp catabolic processGO:00331261660.018
regulation of ion transportGO:00432691890.018
regulation of peptidase activityGO:00525471800.018
purine nucleoside monophosphate metabolic processGO:00091261860.017
histone acetylationGO:0016573930.017
response to nitrogen compoundGO:19016981840.017
regulation of endopeptidase activityGO:00525481700.017
spinal cord developmentGO:002151040.017
microtubule cytoskeleton organizationGO:00002261760.017
regulation of gtpase activityGO:00430871800.017
cellular response to growth factor stimulusGO:00713631970.017
sequestering of calcium ionGO:0051208170.017
positive regulation of cellular component biogenesisGO:00440891580.017
cell part morphogenesisGO:00329901370.017
negative regulation of cell cycleGO:00457861930.017
gtp catabolic processGO:00061842370.017
regulation of protein transportGO:00512232130.017
regulation of protein complex assemblyGO:00432541470.017
cellular cation homeostasisGO:00300031630.017
regulation of response to external stimulusGO:00321012220.017
regulation of protein polymerizationGO:0032271630.016
adult locomotory behaviorGO:000834410.016
regulation of cellular component movementGO:00512703340.016
peptidyl lysine acetylationGO:00183941010.016
actin filament organizationGO:00070151280.016
single organism cellular localizationGO:19025803320.016
posttranscriptional regulation of gene expressionGO:00106082130.016
regulation of protein processingGO:00706131500.016
regulation of meiosisGO:004002030.016
generation of neuronsGO:00486991520.016
anterior posterior axis specification embryoGO:000859520.016
positive regulation of wnt signaling pathwayGO:0030177540.016
positive regulation of purine nucleotide metabolic processGO:19005442270.016
regulation of microtubule based processGO:0032886740.016
regulation of cell morphogenesis involved in differentiationGO:0010769830.016
guanosine containing compound metabolic processGO:19010682440.016
regulation of cell growthGO:00015581350.016
guanosine containing compound catabolic processGO:19010692390.016
positive regulation of cell cycleGO:00457871400.016
positive regulation of hydrolase activityGO:00513453310.016
rna splicingGO:00083801310.016
calcium ion transmembrane transportGO:0070588760.016
negative regulation of cellular amino acid metabolic processGO:004576320.015
tube closureGO:006060630.015
nucleoside monophosphate catabolic processGO:00091251590.015
positive regulation of axon extensionGO:004577340.015
embryonic epithelial tube formationGO:000183840.015
response to abiotic stimulusGO:00096283360.015
receptor mediated endocytosisGO:0006898840.015
oogenesisGO:004847720.015
cellular chemical homeostasisGO:00550821800.015
regulation of immune responseGO:00507762010.015
reproductive processGO:00224141060.015
associative learningGO:000830610.015
purine ribonucleoside monophosphate metabolic processGO:00091671860.015
immune system developmentGO:00025201950.015
Mouse
embryonic placenta developmentGO:000189210.015
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.015
regulation of cellular response to stressGO:00801352440.015
organelle fissionGO:00482851490.015
regulation of cytoplasmic transportGO:19036491490.015
divalent inorganic cation transportGO:00725111580.015
positive regulation of nucleoside metabolic processGO:00459791860.015
regulation of actin cytoskeleton organizationGO:00329561160.015
melanin metabolic processGO:000658210.015
extrinsic apoptotic signaling pathwayGO:00971911190.015
intracellular receptor signaling pathwayGO:00305221040.015
divalent inorganic cation homeostasisGO:00725071360.015
actin mediated cell contractionGO:0070252120.015
positive regulation of nucleotide catabolic processGO:00308131850.015
regulation of purine nucleotide catabolic processGO:00331212050.015
regulation of wnt signaling pathwayGO:00301111230.015
actin polymerization or depolymerizationGO:0008154560.015
negative regulation of peptidase activityGO:0010466910.015
tissue morphogenesisGO:0048729960.015
cellular response to nitrogen compoundGO:19016991440.015
regulation of transporter activityGO:0032409820.015
cell fate determinationGO:000170930.015
divalent metal ion transportGO:00708381520.014
regulation of cytokine productionGO:00018172320.014
positive regulation of cell differentiationGO:00455972110.014
cellular protein complex assemblyGO:00436231880.014
single organism membrane organizationGO:00448022680.014
cellular response to organonitrogen compoundGO:00714171240.014
regulation of cell divisionGO:00513021160.014
regulation of cell migrationGO:00303342890.014
cell developmentGO:00484683280.014
cell morphogenesis involved in differentiationGO:00009041440.014
regulation of cell motilityGO:20001452990.014
regulation of growthGO:00400081650.014
regulation of metal ion transportGO:00109591200.014
protein targetingGO:00066051870.014
positive regulation of purine nucleotide catabolic processGO:00331231850.014
regulation of actin filament polymerizationGO:0030833500.014
ribonucleoside monophosphate metabolic processGO:00091611870.014
regulation of sequence specific dna binding transcription factor activityGO:00510902110.014
carbohydrate derivative biosynthetic processGO:19011372070.014
motor neuron axon guidanceGO:000804520.014
regulation of ion transmembrane transportGO:00347651320.014
response to organonitrogen compoundGO:00102431560.014
purine ribonucleoside monophosphate catabolic processGO:00091691580.014
regulation of response to woundingGO:19030341010.014
wound healingGO:00420601150.013
regulation of ion transmembrane transporter activityGO:0032412720.013
regulation of homeostatic processGO:00328441210.013
actin filament polymerizationGO:0030041450.013
negative regulation of organelle organizationGO:00106391260.013
cell adhesionGO:00071553250.013
response to axon injuryGO:004867810.013
positive regulation of cell proliferationGO:00082843010.013
positive regulation of gtpase activityGO:00435471660.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.013
negative regulation of cellular amine metabolic processGO:003323930.013
cardiovascular system developmentGO:00723582620.013
Mouse
regulation of apoptotic signaling pathwayGO:20012331750.013
lens development in camera type eyeGO:000208820.013
negative regulation of mitotic cell cycleGO:00459301020.013
response to cytokineGO:00340972320.013
negative regulation of endopeptidase activityGO:0010951840.013
protein polymerizationGO:0051258710.013
regulation of cell projection organizationGO:00313441070.013
positive regulation of mitotic cell cycleGO:0045931600.013
single organism carbohydrate metabolic processGO:00447231930.013
detection of chemical stimulusGO:0009593550.013
regulation of transmembrane transporter activityGO:0022898740.013
regulation of gtp catabolic processGO:00331241800.013
positive regulation of protein phosphorylationGO:00019343130.013
organonitrogen compound biosynthetic processGO:19015662000.012
purine nucleoside monophosphate catabolic processGO:00091281580.012
immune effector processGO:00022521590.012
regulation of transmembrane transportGO:00347621390.012
cellular response to cytokine stimulusGO:00713451810.012
regulation of map kinase activityGO:00434051080.012
central nervous system developmentGO:00074171230.012
regulation of defense responseGO:00313471540.012
negative regulation of cell proliferationGO:00082852280.012
carbohydrate metabolic processGO:00059752070.012
cytokine mediated signaling pathwayGO:00192211090.012
oocyte developmentGO:004859910.012
atp catabolic processGO:00062001570.012
neuron developmentGO:00486661130.012
activation of store operated calcium channel activityGO:003223740.012
establishment of protein localization to organelleGO:00725941720.012
circadian behaviorGO:004851220.012
nuclear divisionGO:00002801280.012
organelle assemblyGO:00709251760.012
lipid metabolic processGO:00066293810.012
ribonucleoside monophosphate catabolic processGO:00091581580.012
response to biotic stimulusGO:00096072760.012
regulation of anatomical structure sizeGO:00900661010.012
oocyte differentiationGO:000999420.012
maintenance of location in cellGO:0051651620.012
mitotic spindle elongationGO:000002240.012
sensory perceptionGO:00076001030.012
regulation of intracellular protein transportGO:00331571230.012
convergent extensionGO:006002610.012
organic hydroxy compound metabolic processGO:19016151470.012
covalent chromatin modificationGO:00165692540.012
Human Mouse
axis elongationGO:000340140.012
cellular lipid metabolic processGO:00442553030.012
visual behaviorGO:000763220.012
glial cell migrationGO:000834740.012
negative regulation of homeostatic processGO:0032845590.012
ventral spinal cord developmentGO:002151710.012
regulation of ion homeostasisGO:2000021730.012
spindle elongationGO:005123140.012
photoreceptor cell differentiationGO:004653020.012
cell differentiation in spinal cordGO:002151510.012
neural tube closureGO:000184330.012
response to oxygen containing compoundGO:19017003690.012
cell cycle checkpointGO:00000751170.012
dna integrationGO:001507430.012
positive regulation of apoptotic processGO:00430652460.012
regulation of bindingGO:00510981110.012
regulation of synaptic plasticityGO:004816730.011
establishment of planar polarityGO:000173630.011
blastoderm segmentationGO:000735020.011
inner ear morphogenesisGO:004247240.011
i kappab kinase nf kappab signalingGO:00072491660.011
hemopoiesisGO:00300971800.011
Mouse
cardiac muscle cell contractionGO:008600340.011
oxidation reduction processGO:00551143960.011
nerve developmentGO:002167540.011
response to hypoxiaGO:0001666960.011
regulation of cell shapeGO:0008360480.011
regulation of locomotionGO:00400123290.011
negative regulation of cell cycle processGO:00109481210.011
single organism cell adhesionGO:00986021790.011
positive regulation of transporter activityGO:0032411320.011
limbic system developmentGO:002176130.011
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.011
epithelium developmentGO:00604292270.011
negative regulation of catabolic processGO:00098951040.011
protein dna complex subunit organizationGO:0071824800.011
regulation of intracellular transportGO:00323861950.011
detection of stimulusGO:0051606850.011
positive regulation of protein transportGO:00512221350.011
regulation of cell developmentGO:00602841610.011
rna interferenceGO:001624640.011
regulation of ras gtpase activityGO:00323181280.011
protein acylationGO:00435431380.011
glycoprotein metabolic processGO:00091001100.011
long term memoryGO:000761620.011
positive regulation of intracellular transportGO:00323881040.011
neuroblast proliferationGO:000740540.011
g1 s transition of mitotic cell cycleGO:0000082780.011
chromosome segregationGO:00070591140.011
regulation of i kappab kinase nf kappab signalingGO:00431221620.011
visual learningGO:000854210.011
internal protein amino acid acetylationGO:00064751010.011
regulation of calcium ion transmembrane transporter activityGO:1901019280.011
regulation of axon guidanceGO:190266730.011
endocytosisGO:00068971590.011
regulation of vasculature developmentGO:1901342970.011
negative regulation of proteolysisGO:00458611320.010
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.010
intracellular protein transportGO:00068862700.010
angiogenesisGO:00015251470.010
blastocyst developmentGO:000182430.010
reactive oxygen species biosynthetic processGO:190340940.010
response to metal ionGO:0010038840.010
regulation of actin polymerization or depolymerizationGO:0008064560.010
negative regulation of transportGO:00510511760.010
cellular carbohydrate metabolic processGO:0044262840.010
nitrogen compound transportGO:00717051910.010
maintenance of protein location in cellGO:0032507560.010
urea metabolic processGO:001962730.010
response to other organismGO:00517072610.010
dna conformation changeGO:00711031130.010
rhythmic behaviorGO:000762220.010
positive regulation of synaptic transmissionGO:005080640.010
negative regulation of kinase activityGO:00336731060.010
response to oxygen levelsGO:00704821000.010
canonical wnt signaling pathwayGO:00600701160.010
head developmentGO:00603221080.010
cerebellum developmentGO:002154920.010
cellular response to oxidative stressGO:0034599850.010

ASXL2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.034
central nervous system diseaseDOID:3311860.034
musculoskeletal system diseaseDOID:172230.032
neurodegenerative diseaseDOID:12891020.023
disease of cellular proliferationDOID:145661740.022
cardiovascular system diseaseDOID:12871060.020
connective tissue diseaseDOID:651090.019
auditory system diseaseDOID:2742530.018
sensory system diseaseDOID:00501552030.018
cancerDOID:1621670.017
organ system cancerDOID:00506861640.017
myopathyDOID:4231040.015
muscular diseaseDOID:00800001140.015
muscle tissue diseaseDOID:661130.015
bone diseaseDOID:0080001880.014
nonsyndromic deafnessDOID:0050563500.013
intrinsic cardiomyopathyDOID:0060036500.012
cardiomyopathyDOID:0050700500.012
heart diseaseDOID:114680.012
disease of metabolismDOID:00146672950.012
physical disorderDOID:0080015410.011
congenital nervous system abnormalityDOID:2490210.011
autosomal dominant nonsyndromic deafnessDOID:0050564230.011