Homo sapiens

35 known processes

MTHFR

methylenetetrahydrofolate reductase (NAD(P)H)

MTHFR biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amine metabolic processGO:0044106410.119
cation transportGO:00068123310.099
ion transmembrane transportGO:00342203380.097
regulation of cellular ketone metabolic processGO:0010565500.092
response to oxygen containing compoundGO:19017003690.091
cellular amino acid metabolic processGO:00065201160.089
cellular ketone metabolic processGO:0042180800.085
amine metabolic processGO:0009308440.082
system processGO:00030083490.077
regulation of cellular amino acid metabolic processGO:000652160.074
transmembrane transportGO:00550853990.073
lipid metabolic processGO:00066293810.071
regulation of transferase activityGO:00513383550.071
cellular response to endogenous stimulusGO:00714953360.068
cellular lipid metabolic processGO:00442553030.065
metal ion transportGO:00300012720.065
positive regulation of cellular amine metabolic processGO:003324070.063
post embryonic developmentGO:000979120.061
determination of adult lifespanGO:000834020.056
cellular response to oxygen containing compoundGO:19017012760.056
oxidation reduction processGO:00551143960.055
ion homeostasisGO:00508012300.053
multicellular organismal agingGO:001025930.053
regulation of cellular component biogenesisGO:00440872810.052
female gamete generationGO:000729220.050
response to abiotic stimulusGO:00096283360.049
regulation of cellular amine metabolic processGO:0033238110.049
chemical homeostasisGO:00488783060.048
regulation of kinase activityGO:00435493140.047
cell developmentGO:00484683280.047
single organism carbohydrate metabolic processGO:00447231930.047
regulation of protein kinase activityGO:00458592890.046
organonitrogen compound biosynthetic processGO:19015662000.045
carbohydrate metabolic processGO:00059752070.045
inorganic cation transmembrane transportGO:00986621940.044
negative regulation of phosphate metabolic processGO:00459362670.043
protein catabolic processGO:00301633250.043
cation transmembrane transportGO:00986552380.042
cellular macromolecule catabolic processGO:00442653800.042
neurological system processGO:00508771630.041
small gtpase mediated signal transductionGO:0007264780.041
protein processingGO:00164852260.041
response to organonitrogen compoundGO:00102431560.040
positive regulation of cellular amino acid metabolic processGO:004576430.040
regulation of mapk cascadeGO:00434082620.040
regulation of secretionGO:00510461940.040
regulation of ion transportGO:00432691890.040
monocarboxylic acid metabolic processGO:00327871850.039
secretionGO:00469032540.039
negative regulation of catalytic activityGO:00430863350.039
memoryGO:000761330.039
negative regulation of transportGO:00510511760.038
single organism cellular localizationGO:19025803320.038
anion transportGO:00068201610.038
neuromuscular junction developmentGO:000752830.038
locomotory behaviorGO:000762610.037
negative regulation of protein metabolic processGO:00512483910.036
cellular chemical homeostasisGO:00550821800.036
regulation of purine nucleotide metabolic processGO:19005422640.035
positive regulation of protein phosphorylationGO:00019343130.035
oogenesisGO:004847720.035
regulation of proteolysisGO:00301622930.035
response to nitrogen compoundGO:19016981840.035
response to biotic stimulusGO:00096072760.035
inorganic ion transmembrane transportGO:00986602310.035
regulation of cellular component movementGO:00512703340.035
ras protein signal transductionGO:0007265730.035
cellular macromolecular complex assemblyGO:00346223240.035
organophosphate biosynthetic processGO:00904071630.035
positive regulation of transportGO:00510503360.034
purine ribonucleoside triphosphate metabolic processGO:00092054110.034
cytoplasmic transportGO:00164823790.033
cellular response to nitrogen compoundGO:19016991440.033
negative regulation of cellular protein metabolic processGO:00322693530.033
cellular homeostasisGO:00197251960.033
nitrogen compound transportGO:00717051910.033
vesicle mediated transportGO:00161923710.033
purine ribonucleoside metabolic processGO:00461284370.033
nucleoside catabolic processGO:00091644080.032
ribonucleotide catabolic processGO:00092614050.032
negative regulation of phosphorus metabolic processGO:00105632670.032
purine nucleoside triphosphate metabolic processGO:00091444120.032
purine ribonucleoside catabolic processGO:00461303980.032
positive regulation of cellular component organizationGO:00511303760.031
nucleoside triphosphate metabolic processGO:00091414220.031
fatty acid metabolic processGO:00066311150.031
nucleoside phosphate catabolic processGO:19012924120.031
mapk cascadeGO:00001652880.030
defense responseGO:00069523150.030
chromatin organizationGO:00063253510.030
response to external biotic stimulusGO:00432072610.030
purine containing compound catabolic processGO:00725234110.030
rho protein signal transductionGO:0007266260.030
positive regulation of cellular catabolic processGO:00313312840.030
regulation of locomotionGO:00400123290.030
protein maturationGO:00516042330.030
cell adhesionGO:00071553250.030
purine nucleotide catabolic processGO:00061954050.029
purine nucleoside triphosphate catabolic processGO:00091463920.029
positive regulation of phosphorylationGO:00423273940.029
g protein coupled receptor signaling pathwayGO:00071862070.029
negative regulation of cell deathGO:00605483450.029
rhythmic behaviorGO:000762220.029
immune responseGO:00069553070.029
signal transduction by phosphorylationGO:00230142970.029
regulation of response to external stimulusGO:00321012220.029
purine nucleoside catabolic processGO:00061523980.029
regulation of cell cycleGO:00517263930.029
ribonucleoside triphosphate metabolic processGO:00091994120.029
negative regulation of cellular component organizationGO:00511292350.029
circadian behaviorGO:004851220.029
cellular protein catabolic processGO:00442572610.028
purine ribonucleoside triphosphate catabolic processGO:00092073910.028
ribonucleoside catabolic processGO:00424544060.028
positive regulation of purine nucleotide metabolic processGO:19005442270.028
positive regulation of cell deathGO:00109422630.028
nucleoside triphosphate catabolic processGO:00091433940.028
metal ion homeostasisGO:00550651690.028
regulation of protein localizationGO:00328802960.028
growthGO:00400072020.028
purine ribonucleotide catabolic processGO:00091544040.028
regulation of protein transportGO:00512232130.028
organophosphate catabolic processGO:00464344300.027
protein ubiquitinationGO:00165673140.027
histone modificationGO:00165702510.027
response to cytokineGO:00340972320.027
regulation of cytokine productionGO:00018172320.027
ribonucleoside triphosphate catabolic processGO:00092033910.027
positive regulation of protein kinase activityGO:00458601900.027
oocyte developmentGO:004859910.027
nucleotide catabolic processGO:00091664080.027
cardiac muscle cell contractionGO:008600340.027
positive regulation of transferase activityGO:00513472270.027
carbohydrate derivative biosynthetic processGO:19011372070.027
positive regulation of catabolic processGO:00098963100.027
positive regulation of mapk cascadeGO:00434101900.027
cation homeostasisGO:00550801890.026
guanosine containing compound catabolic processGO:19010692390.026
regulation of ion transmembrane transportGO:00347651320.026
regulation of cell motilityGO:20001452990.026
positive regulation of hydrolase activityGO:00513453310.026
proteolysis involved in cellular protein catabolic processGO:00516032440.026
nervous system developmentGO:00073992930.026
segmentationGO:003528240.026
calcium ion transportGO:00068161470.026
regulation of intracellular transportGO:00323861950.026
response to hormoneGO:00097251750.025
lipid biosynthetic processGO:00086101770.025
regulation of small gtpase mediated signal transductionGO:00510561560.025
covalent chromatin modificationGO:00165692540.025
cellular response to organonitrogen compoundGO:00714171240.025
cellular response to hormone stimulusGO:00328701250.025
gtp catabolic processGO:00061842370.025
regulation of secretion by cellGO:19035301770.025
interspecies interaction between organismsGO:00444191560.025
oocyte differentiationGO:000999420.025
positive regulation of nucleotide metabolic processGO:00459812300.025
regulation of cell migrationGO:00303342890.025
negative regulation of multicellular organismal processGO:00512413170.025
membrane organizationGO:00610242920.024
actin filament based processGO:00300292240.024
protein modification by small protein conjugationGO:00324463420.024
response to lipidGO:00339932060.024
positive regulation of kinase activityGO:00336742040.024
protein localization to organelleGO:00333652800.024
small molecule biosynthetic processGO:00442831570.024
cardiovascular system developmentGO:00723582620.024
spermatid differentiationGO:004851540.024
positive regulation of immune system processGO:00026842830.024
glycosyl compound catabolic processGO:19016584130.024
secretion by cellGO:00329402260.024
response to other organismGO:00517072610.024
guanosine containing compound metabolic processGO:19010682440.024
regulation of nucleotide metabolic processGO:00061402690.023
purine nucleotide biosynthetic processGO:0006164840.023
regulation of cell differentiationGO:00455953930.023
cellular component morphogenesisGO:00329893140.023
enzyme linked receptor protein signaling pathwayGO:00071673030.023
blood circulationGO:00080151130.023
regulation of anatomical structure morphogenesisGO:00226032860.023
negative regulation of cellular amino acid metabolic processGO:004576320.023
mitotic cell cycleGO:00002783260.023
biological adhesionGO:00226103310.023
single organism membrane organizationGO:00448022680.023
monovalent inorganic cation transportGO:00156721280.023
positive regulation of programmed cell deathGO:00430682490.023
regulation of defense responseGO:00313471540.023
intracellular protein transportGO:00068862700.023
regenerationGO:003109940.023
spermatid developmentGO:000728640.023
anterior posterior axis specificationGO:000994820.023
negative regulation of programmed cell deathGO:00430693210.023
organic anion transportGO:00157111030.023
chromatin modificationGO:00165682980.023
gtp metabolic processGO:00460392390.023
regulation of protein catabolic processGO:00421761550.022
negative regulation of apoptotic processGO:00430663160.022
multi organism cellular processGO:00447641560.022
divalent inorganic cation transportGO:00725111580.022
mitotic cell cycle processGO:19030472860.022
circulatory system processGO:00030131130.022
regulation of gtp catabolic processGO:00331241800.022
protein oligomerizationGO:00512591730.022
regulation of metal ion transportGO:00109591200.022
modification dependent protein catabolic processGO:00199412090.022
regulation of purine nucleotide catabolic processGO:00331212050.022
negative regulation of cellular amine metabolic processGO:003323930.022
cellular organohalogen metabolic processGO:009034520.022
innate immune responseGO:00450871780.022
positive regulation of organelle organizationGO:00106381950.021
muscle system processGO:0003012810.021
glycerolipid metabolic processGO:00464861070.021
negative regulation of hydrolase activityGO:00513461820.021
response to organic cyclic compoundGO:00140702040.021
long chain fatty acid metabolic processGO:0001676300.021
ubiquitin dependent protein catabolic processGO:00065112060.021
symbiosis encompassing mutualism through parasitismGO:00444031560.021
protein targetingGO:00066051870.021
cell morphogenesisGO:00009022960.021
modification dependent macromolecule catabolic processGO:00436322120.020
regulation of transmembrane transportGO:00347621390.020
regulation of protein serine threonine kinase activityGO:00719001790.020
regulation of establishment of protein localizationGO:00702012420.020
regulation of ras protein signal transductionGO:00465781550.020
cellular cation homeostasisGO:00300031630.020
dephosphorylationGO:00163112090.020
apoptotic signaling pathwayGO:00971902680.020
divalent metal ion transportGO:00708381520.020
cellular protein complex assemblyGO:00436231880.020
associative learningGO:000830610.020
regulation of protein maturationGO:19033171500.020
negative regulation of intracellular signal transductionGO:19025321830.020
regulation of immune responseGO:00507762010.020
positive regulation of developmental processGO:00510943140.019
proteasomal protein catabolic processGO:00104981760.019
regulation of gtpase activityGO:00430871800.019
nucleoside phosphate biosynthetic processGO:19012931090.019
regulation of membrane potentialGO:0042391950.019
regulation of muscle system processGO:0090257530.019
purine ribonucleotide biosynthetic processGO:0009152790.019
cardiac muscle contractionGO:0060048340.019
maintenance of locationGO:00512351120.019
tripartite regional subdivisionGO:000735120.019
viral processGO:00160321460.019
negative regulation of proteolysisGO:00458611320.019
cytokine productionGO:00018162470.019
leukocyte activationGO:00453211640.019
positive regulation of nucleotide catabolic processGO:00308131850.019
actin filament based movementGO:0030048170.018
regulation of cyclic nucleotide biosynthetic processGO:0030802490.018
blastoderm segmentationGO:000735020.018
regulation of multi organism processGO:00439001570.018
cell cell signalingGO:00072671550.018
negative regulation of cell proliferationGO:00082852280.018
carboxylic acid biosynthetic processGO:0046394970.018
regulation of transmembrane transporter activityGO:0022898740.018
regulation of protein complex assemblyGO:00432541470.018
positive regulation of cytokine productionGO:00018191670.018
response to growth factorGO:00708482050.018
regulation of cell cycle processGO:00105642660.018
cell projection organizationGO:00300302520.018
negative regulation of protein modification processGO:00314002000.018
cell growthGO:00160491600.018
regulation of apoptotic signaling pathwayGO:20012331750.018
negative regulation of protein maturationGO:19033181420.018
negative regulation of transferase activityGO:00513481240.018
peptidyl tyrosine phosphorylationGO:00181081700.018
establishment of protein localization to organelleGO:00725941720.018
purine containing compound biosynthetic processGO:0072522880.018
viral life cycleGO:00190581320.018
regulation of cytoskeleton organizationGO:00514931770.018
positive regulation of immune responseGO:00507781590.018
peptidyl tyrosine modificationGO:00182121700.017
circulatory system developmentGO:00723592620.017
positive regulation of purine nucleotide catabolic processGO:00331231850.017
negative regulation of phosphorylationGO:00423261740.017
positive regulation of camp biosynthetic processGO:0030819350.017
positive regulation of apoptotic processGO:00430652460.017
nucleocytoplasmic transportGO:00069131760.017
posttranscriptional regulation of gene expressionGO:00106082130.017
positive regulation of gtp catabolic processGO:00331261660.017
regulation of growthGO:00400081650.017
regulation of bindingGO:00510981110.017
cellular metal ion homeostasisGO:00068751460.017
camp biosynthetic processGO:0006171470.017
response to virusGO:00096151260.017
stem cell divisionGO:001714520.017
muscle contractionGO:0006936730.017
positive regulation of cell proliferationGO:00082843010.017
action potentialGO:0001508340.017
nucleotide biosynthetic processGO:00091651090.017
divalent inorganic cation homeostasisGO:00725071360.017
compound eye developmentGO:004874910.017
response to radiationGO:00093141510.017
cellular response to dna damage stimulusGO:00069743790.017
organic acid biosynthetic processGO:0016053970.017
nuclear transportGO:00511691790.017
ribose phosphate biosynthetic processGO:0046390820.017
regulation of ras gtpase activityGO:00323181280.016
adult locomotory behaviorGO:000834410.016
regulation of cellular response to stressGO:00801352440.016
morphogenesis of embryonic epitheliumGO:001633140.016
regulation of cytoplasmic transportGO:19036491490.016
peptidyl serine phosphorylationGO:00181051010.016
positive regulation of protein transportGO:00512221350.016
regulation of transporter activityGO:0032409820.016
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.016
striated muscle contractionGO:0006941520.016
positive regulation of nucleoside metabolic processGO:00459791860.016
positive regulation of gtpase activityGO:00435471660.016
peptidyl lysine modificationGO:00182051440.016
response to inorganic substanceGO:00100351270.016
mitochondrion organizationGO:00070051560.016
anterior posterior axis specification embryoGO:000859520.016
circadian sleep wake cycle sleepGO:005080220.016
defense response to other organismGO:00985421290.016
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.016
cyclic purine nucleotide metabolic processGO:0052652600.016
regulation of actin filament based processGO:00329701410.016
negative regulation of organelle organizationGO:00106391260.016
cell activationGO:00017752130.016
reactive oxygen species metabolic processGO:0072593750.016
regulation of dna metabolic processGO:00510521530.016
regulation of synaptic plasticityGO:004816730.016
positive regulation of cytosolic calcium ion concentrationGO:0007204820.016
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.016
protein acylationGO:00435431380.016
behaviorGO:00076101120.016
cofactor metabolic processGO:0051186870.016
organelle assemblyGO:00709251760.016
regulation of protein processingGO:00706131500.015
naphthalene containing compound metabolic processGO:009042010.015
organ formationGO:004864530.015
cyclic nucleotide biosynthetic processGO:0009190610.015
peptidyl serine modificationGO:00182091060.015
negative regulation of cell cycleGO:00457861930.015
reactive nitrogen species metabolic processGO:200105730.015
sulfur compound metabolic processGO:00067901010.015
endosomal transportGO:00161971290.015
regulation of mitotic cell cycleGO:00073461890.015
negative regulation of protein processingGO:00109551420.015
regulation of nucleoside metabolic processGO:00091182090.015
positive regulation of secretion by cellGO:19035321080.015
negative regulation of kinase activityGO:00336731060.015
positive regulation of locomotionGO:00400171860.015
ribonucleotide biosynthetic processGO:0009260810.015
sensory perception of painGO:001923340.015
blood vessel morphogenesisGO:00485141620.015
regulation of nucleotide catabolic processGO:00308112050.015
cellular calcium ion homeostasisGO:00068741170.015
regulation of cell developmentGO:00602841610.015
embryonic epithelial tube formationGO:000183840.015
regulation of response to woundingGO:19030341010.015
actin filament organizationGO:00070151280.015
response to oxidative stressGO:00069791210.015
cellular response to cytokine stimulusGO:00713451810.014
protein autophosphorylationGO:00467771230.014
response to fungusGO:000962040.014
neuroblast proliferationGO:000740540.014
negative regulation of catabolic processGO:00098951040.014
cellular ion homeostasisGO:00068731680.014
negative regulation of locomotionGO:00400131180.014
methylationGO:00322591060.014
regulation of nucleotide biosynthetic processGO:0030808500.014
i kappab kinase nf kappab signalingGO:00072491660.014
nitrogen cycle metabolic processGO:007194130.014
ribonucleoside monophosphate metabolic processGO:00091611870.014
response to axon injuryGO:004867810.014
lipid catabolic processGO:0016042840.014
response to woundingGO:00096111680.014
regulation of meiotic cell cycleGO:005144540.014
sensory perception of smellGO:000760820.014
positive regulation of cyclic nucleotide biosynthetic processGO:0030804380.014
microtubule based processGO:00070172100.014
hexose metabolic processGO:0019318550.014
long term memoryGO:000761620.014
endocytosisGO:00068971590.014
regulation of cellular protein catabolic processGO:1903362960.014
anatomical structure formation involved in morphogenesisGO:00486462840.014
negative regulation of synaptic transmissionGO:005080520.014
syncytium formation by plasma membrane fusionGO:000076820.014
reactive oxygen species biosynthetic processGO:190340940.014
regulation of intracellular protein transportGO:00331571230.014
sleepGO:003043120.014
coenzyme metabolic processGO:0006732650.014
positive regulation of nucleotide biosynthetic processGO:0030810380.014
positive regulation of cellular component biogenesisGO:00440891580.014
regulation of map kinase activityGO:00434051080.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.013
visual behaviorGO:000763220.013
negative regulation of growthGO:0045926970.013
negative regulation of cellular catabolic processGO:0031330830.013
generation of neuronsGO:00486991520.013
positive regulation of ion transportGO:0043270870.013
activation of protein kinase activityGO:0032147900.013
positive regulation of purine nucleotide biosynthetic processGO:1900373380.013
monocarboxylic acid biosynthetic processGO:0072330670.013
positive regulation of ras gtpase activityGO:00323201170.013
protein localization to nucleusGO:00345041360.013
regulation of peptidyl tyrosine phosphorylationGO:00507301080.013
regulation of reactive oxygen species metabolic processGO:2000377410.013
naphthalene metabolic processGO:001893110.013
cellular response to abiotic stimulusGO:00712141170.013
immune effector processGO:00022521590.013
actin mediated cell contractionGO:0070252120.013
negative regulation of protein phosphorylationGO:00019331400.013
negative regulation of immune system processGO:00026831360.013
peripheral nervous system developmentGO:000742220.013
organelle fissionGO:00482851490.013
coumarin metabolic processGO:000980420.013
neurogenesisGO:00220081690.013
regulation of i kappab kinase nf kappab signalingGO:00431221620.013
response to peptideGO:1901652650.013
organic acid transportGO:0015849650.013
microtubule cytoskeleton organizationGO:00002261760.013
positive regulation of protein serine threonine kinase activityGO:00719021190.013
epithelial cell migrationGO:00106311190.013
positive regulation of cell migrationGO:00303351720.013
response to bacteriumGO:00096171440.013
demethylationGO:0070988370.013
unsaturated fatty acid metabolic processGO:0033559370.013
primary neural tube formationGO:001402030.013
nuclear importGO:00511701060.013
small molecule catabolic processGO:0044282920.013
regulation of cell growthGO:00015581350.013
epithelium migrationGO:00901321190.013
calcium ion homeostasisGO:00550741220.013
regulation of system processGO:00440571010.012
phospholipid metabolic processGO:0006644990.012
negative regulation of blood pressureGO:004577630.012
circadian sleep wake cycleGO:004274520.012
positive regulation of proteolysisGO:00458621420.012
second messenger mediated signalingGO:0019932780.012
regulation of innate immune responseGO:0045088970.012
cell substrate adhesionGO:00315891320.012
response to drugGO:0042493810.012
protein importGO:00170381300.012
regulation of vesicle mediated transportGO:00606271300.012
autophagyGO:0006914880.012
regulation of dephosphorylationGO:0035303960.012
cell cycle phase transitionGO:00447701730.012
regulation of camp biosynthetic processGO:0030817450.012
negative regulation of protein kinase activityGO:0006469980.012
positive regulation of cellular component movementGO:00512721810.012
anion transmembrane transportGO:0098656760.012
sensory perceptionGO:00076001030.012
cgmp catabolic processGO:004606930.012
monosaccharide metabolic processGO:0005996740.012
cell divisionGO:00513011680.012
immune response activating signal transductionGO:0002757900.012
myoblast fusionGO:000752010.012
macromolecule methylationGO:0043414970.012
urea metabolic processGO:001962730.012
rna processingGO:00063962550.012
cellular response to organic cyclic compoundGO:00714071270.012
regulation of circadian sleep wake cycleGO:004274920.012
regulation of reactive oxygen species biosynthetic processGO:190342630.012
regulation of calcium ion transportGO:0051924790.012
regulation of anatomical structure sizeGO:00900661010.012
sequestering of metal ionGO:0051238240.012
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
immune system developmentGO:00025201950.012
positive regulation of nf kappab transcription factor activityGO:0051092810.012
cellular amide metabolic processGO:0043603690.012
ameboidal type cell migrationGO:00016671350.012
epoxygenase p450 pathwayGO:001937330.012
histone acetylationGO:0016573930.012
myeloid cell differentiationGO:00300991170.012
cellular carbohydrate metabolic processGO:0044262840.012
tube closureGO:006060630.012
regulation of cell morphogenesisGO:00226041530.012
regulation of actin cytoskeleton organizationGO:00329561160.012
lipid localizationGO:00108761060.012

MTHFR disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.062
central nervous system diseaseDOID:3311860.042
nervous system diseaseDOID:8634310.042
musculoskeletal system diseaseDOID:172230.039
inherited metabolic disorderDOID:6552420.032
neurodegenerative diseaseDOID:12891020.021
cancerDOID:1621670.021
disease of cellular proliferationDOID:145661740.021
cardiovascular system diseaseDOID:12871060.020
muscular diseaseDOID:00800001140.019
organ system cancerDOID:00506861640.019
myopathyDOID:4231040.019
muscle tissue diseaseDOID:661130.019
sensory system diseaseDOID:00501552030.017
immune system diseaseDOID:29141550.017
connective tissue diseaseDOID:651090.015
eye and adnexa diseaseDOID:14921500.014
eye diseaseDOID:56141490.014
brain diseaseDOID:936730.014
bone diseaseDOID:0080001880.014