Homo sapiens

0 known processes

SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

(Aliases: CAT2,HCAT2,ATRC2)

SLC7A2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amine metabolic processGO:0044106410.172
cellular ketone metabolic processGO:0042180800.160
regulation of cellular ketone metabolic processGO:0010565500.136
amine metabolic processGO:0009308440.131
cellular amino acid metabolic processGO:00065201160.119
positive regulation of phosphorylationGO:00423273940.112
regulation of cellular amine metabolic processGO:0033238110.111
positive regulation of cellular amine metabolic processGO:003324070.106
regulation of cellular amino acid metabolic processGO:000652160.101
response to oxygen containing compoundGO:19017003690.094
positive regulation of cellular amino acid metabolic processGO:004576430.090
cellular response to endogenous stimulusGO:00714953360.081
system processGO:00030083490.081
lipid metabolic processGO:00066293810.077
positive regulation of protein phosphorylationGO:00019343130.074
post embryonic developmentGO:000979120.067
cation transportGO:00068123310.065
Rat
metal ion transportGO:00300012720.064
positive regulation of transportGO:00510503360.063
regulation of cell differentiationGO:00455953930.061
regulation of transferase activityGO:00513383550.060
response to abiotic stimulusGO:00096283360.060
female gamete generationGO:000729220.058
positive regulation of developmental processGO:00510943140.058
regulation of hormone levelsGO:00108171250.058
chemical homeostasisGO:00488783060.058
mapk cascadeGO:00001652880.056
negative regulation of protein metabolic processGO:00512483910.056
signal transduction by phosphorylationGO:00230142970.056
carbohydrate metabolic processGO:00059752070.056
response to organic cyclic compoundGO:00140702040.053
single organism carbohydrate metabolic processGO:00447231930.052
regulation of kinase activityGO:00435493140.052
cellular lipid metabolic processGO:00442553030.051
negative regulation of multicellular organismal processGO:00512413170.051
regulation of secretionGO:00510461940.049
nervous system developmentGO:00073992930.049
regulation of locomotionGO:00400123290.048
ion homeostasisGO:00508012300.047
secretion by cellGO:00329402260.047
locomotory behaviorGO:000762610.047
ion transmembrane transportGO:00342203380.046
Rat
cell adhesionGO:00071553250.046
defense responseGO:00069523150.046
regulation of mapk cascadeGO:00434082620.046
metal ion homeostasisGO:00550651690.046
transmembrane transportGO:00550853990.046
Rat
vesicle mediated transportGO:00161923710.046
cellular homeostasisGO:00197251960.045
determination of adult lifespanGO:000834020.045
organophosphate catabolic processGO:00464344300.045
positive regulation of cell proliferationGO:00082843010.045
cellular response to oxygen containing compoundGO:19017012760.045
multicellular organismal agingGO:001025930.045
purine nucleotide catabolic processGO:00061954050.045
organonitrogen compound biosynthetic processGO:19015662000.044
positive regulation of protein kinase activityGO:00458601900.044
response to hormoneGO:00097251750.043
purine ribonucleotide catabolic processGO:00091544040.043
carbohydrate derivative biosynthetic processGO:19011372070.042
cell developmentGO:00484683280.042
secretionGO:00469032540.042
regulation of protein kinase activityGO:00458592890.042
regulation of protein localizationGO:00328802960.042
positive regulation of hydrolase activityGO:00513453310.042
oogenesisGO:004847720.041
cellular chemical homeostasisGO:00550821800.041
regulation of cell cycleGO:00517263930.041
regulation of nucleotide metabolic processGO:00061402690.040
purine containing compound catabolic processGO:00725234110.040
response to nitrogen compoundGO:19016981840.040
negative regulation of phosphorus metabolic processGO:00105632670.040
Human
negative regulation of cellular protein metabolic processGO:00322693530.040
negative regulation of catalytic activityGO:00430863350.040
Human
organic hydroxy compound metabolic processGO:19016151470.039
nucleoside triphosphate metabolic processGO:00091414220.039
segmentationGO:003528240.039
purine ribonucleoside metabolic processGO:00461284370.039
cyclic nucleotide metabolic processGO:0009187820.039
regulation of cellular component movementGO:00512703340.039
biological adhesionGO:00226103310.038
response to lipidGO:00339932060.038
positive regulation of cellular component organizationGO:00511303760.038
regenerationGO:003109940.038
anion transportGO:00068201610.038
Rat
positive regulation of transferase activityGO:00513472270.038
ras protein signal transductionGO:0007265730.038
negative regulation of apoptotic processGO:00430663160.037
positive regulation of purine nucleotide metabolic processGO:19005442270.037
single organism cellular localizationGO:19025803320.037
regulation of protein transportGO:00512232130.037
cellular ion homeostasisGO:00068731680.037
negative regulation of cell deathGO:00605483450.037
monocarboxylic acid metabolic processGO:00327871850.036
inorganic ion transmembrane transportGO:00986602310.036
negative regulation of phosphate metabolic processGO:00459362670.036
Human
small gtpase mediated signal transductionGO:0007264780.036
purine ribonucleoside triphosphate metabolic processGO:00092054110.036
immune responseGO:00069553070.036
regulation of cytokine productionGO:00018172320.036
cellular divalent inorganic cation homeostasisGO:00725031280.036
cellular component morphogenesisGO:00329893140.036
ribonucleotide catabolic processGO:00092614050.035
cardiovascular system developmentGO:00723582620.035
response to growth factorGO:00708482050.035
cation homeostasisGO:00550801890.035
regulation of secretion by cellGO:19035301770.035
negative regulation of programmed cell deathGO:00430693210.035
regulation of cell migrationGO:00303342890.035
glycosyl compound catabolic processGO:19016584130.035
oxidation reduction processGO:00551143960.035
purine ribonucleoside catabolic processGO:00461303980.035
positive regulation of catabolic processGO:00098963100.035
apoptotic signaling pathwayGO:00971902680.035
ribonucleoside catabolic processGO:00424544060.034
regulation of purine nucleotide metabolic processGO:19005422640.034
positive regulation of nucleotide metabolic processGO:00459812300.034
enzyme linked receptor protein signaling pathwayGO:00071673030.034
divalent inorganic cation homeostasisGO:00725071360.034
epithelium developmentGO:00604292270.034
regulation of cell adhesionGO:00301551660.034
g protein coupled receptor signaling pathwayGO:00071862070.034
ribonucleoside triphosphate catabolic processGO:00092033910.034
cellular response to organic cyclic compoundGO:00714071270.034
positive regulation of kinase activityGO:00336742040.033
response to biotic stimulusGO:00096072760.033
hematopoietic or lymphoid organ developmentGO:00485341860.033
cytoplasmic transportGO:00164823790.033
purine ribonucleoside triphosphate catabolic processGO:00092073910.033
nucleotide catabolic processGO:00091664080.033
regulation of establishment of protein localizationGO:00702012420.033
growthGO:00400072020.033
hemopoiesisGO:00300971800.033
regulation of cell motilityGO:20001452990.033
cellular response to dna damage stimulusGO:00069743790.032
response to other organismGO:00517072610.032
memoryGO:000761330.032
cell morphogenesisGO:00009022960.032
regulation of cell cycle processGO:00105642660.032
nucleoside phosphate catabolic processGO:19012924120.032
positive regulation of cellular catabolic processGO:00313312840.032
negative regulation of cell proliferationGO:00082852280.032
purine nucleoside catabolic processGO:00061523980.031
response to organonitrogen compoundGO:00102431560.031
positive regulation of mapk cascadeGO:00434101900.031
blood circulationGO:00080151130.031
nucleoside catabolic processGO:00091644080.031
cytokine productionGO:00018162470.031
regulation of proteolysisGO:00301622930.031
purine nucleoside triphosphate metabolic processGO:00091444120.031
peptidyl tyrosine modificationGO:00182121700.031
neurological system processGO:00508771630.030
protein maturationGO:00516042330.030
regulation of system processGO:00440571010.030
ribonucleoside triphosphate metabolic processGO:00091994120.030
negative regulation of developmental processGO:00510932470.030
nucleoside triphosphate catabolic processGO:00091433940.030
organophosphate biosynthetic processGO:00904071630.029
purine nucleoside triphosphate catabolic processGO:00091463920.029
cellular cation homeostasisGO:00300031630.029
protein catabolic processGO:00301633250.029
response to external biotic stimulusGO:00432072610.029
cation transmembrane transportGO:00986552380.029
Rat
hindbrain developmentGO:003090230.029
positive regulation of cell deathGO:00109422630.029
positive regulation of immune system processGO:00026842830.029
regulation of cellular component biogenesisGO:00440872810.029
dephosphorylationGO:00163112090.029
Human
positive regulation of locomotionGO:00400171860.029
cellular metal ion homeostasisGO:00068751460.028
cellular response to growth factor stimulusGO:00713631970.028
immune system developmentGO:00025201950.028
circulatory system developmentGO:00723592620.028
nitrogen compound transportGO:00717051910.028
Rat
positive regulation of cell differentiationGO:00455972110.028
regulation of cellular response to stressGO:00801352440.028
positive regulation of programmed cell deathGO:00430682490.028
membrane organizationGO:00610242920.028
regulation of response to external stimulusGO:00321012220.028
regulation of ion transportGO:00432691890.028
peptidyl tyrosine phosphorylationGO:00181081700.028
response to woundingGO:00096111680.027
reactive oxygen species metabolic processGO:0072593750.027
divalent inorganic cation transportGO:00725111580.027
lipid biosynthetic processGO:00086101770.027
morphogenesis of embryonic epitheliumGO:001633140.027
intracellular protein transportGO:00068862700.027
small molecule biosynthetic processGO:00442831570.027
neuromuscular junction developmentGO:000752830.027
regulation of growthGO:00400081650.027
actin filament based processGO:00300292240.027
negative regulation of transportGO:00510511760.027
positive regulation of cell motilityGO:20001471770.026
anterior posterior axis specificationGO:000994820.026
reactive nitrogen species metabolic processGO:200105730.026
anatomical structure formation involved in morphogenesisGO:00486462840.026
single organism membrane organizationGO:00448022680.026
maintenance of locationGO:00512351120.026
calcium ion homeostasisGO:00550741220.026
purine ribonucleotide biosynthetic processGO:0009152790.026
camp biosynthetic processGO:0006171470.026
divalent metal ion transportGO:00708381520.026
cell projection organizationGO:00300302520.026
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.025
protein processingGO:00164852260.025
regulation of apoptotic signaling pathwayGO:20012331750.025
nucleotide biosynthetic processGO:00091651090.025
cellular response to lipidGO:00713961270.025
nucleoside phosphate biosynthetic processGO:19012931090.025
cellular macromolecular complex assemblyGO:00346223240.025
calcium ion transportGO:00068161470.025
protein localization to organelleGO:00333652800.025
negative regulation of intracellular signal transductionGO:19025321830.025
response to cytokineGO:00340972320.025
regulation of metal ion transportGO:00109591200.025
peripheral nervous system developmentGO:000742220.025
cellular calcium ion homeostasisGO:00068741170.024
blastoderm segmentationGO:000735020.024
organ morphogenesisGO:00098871470.024
rho protein signal transductionGO:0007266260.024
cell cell signalingGO:00072671550.024
guanosine containing compound catabolic processGO:19010692390.024
mitotic cell cycleGO:00002783260.024
reactive oxygen species biosynthetic processGO:190340940.024
alcohol metabolic processGO:00060661140.024
positive regulation of cytokine productionGO:00018191670.023
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.023
regulation of reactive oxygen species metabolic processGO:2000377410.023
regulation of multi organism processGO:00439001570.023
neuron differentiationGO:00301821380.023
positive regulation of cell migrationGO:00303351720.023
epithelial cell differentiationGO:00308551410.023
protein targetingGO:00066051870.023
positive regulation of cellular component movementGO:00512721810.023
erk1 and erk2 cascadeGO:00703711040.023
regulation of nucleoside metabolic processGO:00091182090.022
cellular macromolecule catabolic processGO:00442653800.022
response to inorganic substanceGO:00100351270.022
camp metabolic processGO:0046058610.022
purine containing compound biosynthetic processGO:0072522880.022
guanosine containing compound metabolic processGO:19010682440.022
oocyte developmentGO:004859910.022
protein ubiquitinationGO:00165673140.022
cyclic nucleotide biosynthetic processGO:0009190610.022
negative regulation of cellular amino acid metabolic processGO:004576320.022
epithelial cell proliferationGO:00506731280.022
inorganic cation transmembrane transportGO:00986621940.022
positive regulation of nucleotide catabolic processGO:00308131850.022
regulation of transmission of nerve impulseGO:005196920.021
cellular carbohydrate metabolic processGO:0044262840.021
oocyte differentiationGO:000999420.021
rhythmic behaviorGO:000762220.021
viral processGO:00160321460.021
cell growthGO:00160491600.021
associative learningGO:000830610.021
ribose phosphate biosynthetic processGO:0046390820.021
protein modification by small protein conjugationGO:00324463420.021
positive regulation of apoptotic processGO:00430652460.021
regulation of intracellular transportGO:00323861950.021
regulation of reactive oxygen species biosynthetic processGO:190342630.021
positive regulation of organelle organizationGO:00106381950.021
regulation of purine nucleotide catabolic processGO:00331212050.021
regulation of peptidase activityGO:00525471800.021
negative regulation of cellular amine metabolic processGO:003323930.021
cellular response to cytokine stimulusGO:00713451810.021
neurogenesisGO:00220081690.021
response to radiationGO:00093141510.020
negative regulation of hydrolase activityGO:00513461820.020
Human
embryonic epithelial tube formationGO:000183840.020
gtp catabolic processGO:00061842370.020
inner ear morphogenesisGO:004247240.020
regulation of immune responseGO:00507762010.020
interspecies interaction between organismsGO:00444191560.020
photoreceptor cell differentiationGO:004653020.020
regulation of nucleotide catabolic processGO:00308112050.020
regulation of cell growthGO:00015581350.020
positive regulation of gtpase activityGO:00435471660.020
immune effector processGO:00022521590.020
mitotic cell cycle processGO:19030472860.020
positive regulation of nucleoside metabolic processGO:00459791860.020
matingGO:000761810.020
salivary gland morphogenesisGO:000743540.020
regulation of anatomical structure morphogenesisGO:00226032860.020
negative regulation of protein modification processGO:00314002000.020
positive regulation of protein serine threonine kinase activityGO:00719021190.020
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.020
regulation of synaptic plasticityGO:004816730.020
regulation of transmembrane transportGO:00347621390.020
startle responseGO:000196430.020
innate immune responseGO:00450871780.020
anterior posterior axis specification embryoGO:000859520.020
circadian behaviorGO:004851220.020
cellular protein catabolic processGO:00442572610.019
gtp metabolic processGO:00460392390.019
establishment of protein localization to organelleGO:00725941720.019
positive regulation of secretion by cellGO:19035321080.019
glycerolipid metabolic processGO:00464861070.019
cellular response to organonitrogen compoundGO:00714171240.019
myeloid cell differentiationGO:00300991170.019
regulation of epithelial cell proliferationGO:00506781130.019
neural crest cell developmentGO:001403230.019
regulation of endopeptidase activityGO:00525481700.019
protein oligomerizationGO:00512591730.019
regulation of lipid metabolic processGO:0019216960.019
vasculature developmentGO:00019441810.019
spermatid differentiationGO:004851540.019
chromatin organizationGO:00063253510.019
positive regulation of synaptic transmissionGO:005080640.019
tube developmentGO:00352951250.019
peptidyl serine modificationGO:00182091060.019
multi organism cellular processGO:00447641560.019
nerve developmentGO:002167540.019
regulation of protein serine threonine kinase activityGO:00719001790.019
gamma aminobutyric acid signaling pathwayGO:000721430.019
tripartite regional subdivisionGO:000735120.019
generation of neuronsGO:00486991520.019
fatty acid metabolic processGO:00066311150.019
single organism cell adhesionGO:00986021790.019
regulation of peptidyl tyrosine phosphorylationGO:00507301080.019
negative regulation of cellular component organizationGO:00511292350.019
neuron projection regenerationGO:003110210.019
positive regulation of protein transportGO:00512221350.019
actin cytoskeleton organizationGO:00300362070.019
regulation of cell developmentGO:00602841610.019
regulation of gtp catabolic processGO:00331241800.019
detection of stimulusGO:0051606850.019
regulation of dna metabolic processGO:00510521530.019
central nervous system developmentGO:00074171230.018
positive regulation of reactive oxygen species biosynthetic processGO:190342820.018
regulation of defense responseGO:00313471540.018
negative regulation of phosphorylationGO:00423261740.018
limbic system developmentGO:002176130.018
positive regulation of ion transportGO:0043270870.018
regulation of protein maturationGO:19033171500.018
single organismal cell cell adhesionGO:00163371480.018
blood vessel developmentGO:00015681720.018
motor neuron axon guidanceGO:000804520.018
stem cell divisionGO:001714520.018
regulation of camp metabolic processGO:0030814520.018
symbiosis encompassing mutualism through parasitismGO:00444031560.018
cellular protein complex assemblyGO:00436231880.018
adult locomotory behaviorGO:000834410.018
neuroblast proliferationGO:000740540.018
circulatory system processGO:00030131130.018
regulation of sequence specific dna binding transcription factor activityGO:00510902110.018
cellular response to nitrogen compoundGO:19016991440.018
cyclic purine nucleotide metabolic processGO:0052652600.018
negative regulation of cell cycleGO:00457861930.018
cytosolic calcium ion homeostasisGO:0051480890.018
chromatin modificationGO:00165682980.018
positive regulation of gtp catabolic processGO:00331261660.018
viral life cycleGO:00190581320.018
hormone transportGO:0009914680.018
negative regulation of protein maturationGO:19033181420.018
nuclear transportGO:00511691790.018
positive regulation of secretionGO:00510471160.018
cellular organohalogen metabolic processGO:009034520.018
positive regulation of purine nucleotide catabolic processGO:00331231850.018
tissue regenerationGO:004224630.017
compound eye developmentGO:004874910.017
ameboidal type cell migrationGO:00016671350.017
positive regulation of reactive oxygen species metabolic processGO:2000379240.017
blood vessel morphogenesisGO:00485141620.017
organic anion transportGO:00157111030.017
Rat
regulation of protein catabolic processGO:00421761550.017
regulation of small gtpase mediated signal transductionGO:00510561560.017
regulation of protein secretionGO:0050708860.017
protein localization to membraneGO:00726571600.017
cellular response to hormone stimulusGO:00328701250.017
regulation of gtpase activityGO:00430871800.017
pituitary gland developmentGO:002198320.017
positive regulation of acrosome reactionGO:200034440.017
cell activationGO:00017752130.017
nucleocytoplasmic transportGO:00069131760.017
positive regulation of cell cycleGO:00457871400.017
proteolysis involved in cellular protein catabolic processGO:00516032440.017
reproductive processGO:00224141060.017
spermatid developmentGO:000728640.017
regulation of response to woundingGO:19030341010.017
lipid transportGO:0006869900.017
negative regulation of synaptic transmissionGO:005080520.017
multicellular organismal response to stressGO:003355510.017
response to axon injuryGO:004867810.017
regulation of bindingGO:00510981110.017
monovalent inorganic cation transportGO:00156721280.017
response to metal ionGO:0010038840.017
posttranscriptional regulation of gene expressionGO:00106082130.017
negative regulation of cell differentiationGO:00455961710.017
negative regulation of locomotionGO:00400131180.017
i kappab kinase nf kappab signalingGO:00072491660.017
purine nucleotide biosynthetic processGO:0006164840.017
signal releaseGO:0023061700.017
negative regulation of gliogenesisGO:001401430.017
hormone metabolic processGO:0042445610.017
monosaccharide metabolic processGO:0005996740.017
endocytosisGO:00068971590.017
behaviorGO:00076101120.016
negative regulation of cellular component movementGO:00512711060.016
regulation of ion transmembrane transportGO:00347651320.016
organic acid biosynthetic processGO:0016053970.016
ossificationGO:00015031210.016
sensory perception of painGO:001923340.016
regulation of ras protein signal transductionGO:00465781550.016
response to oxidative stressGO:00069791210.016
sulfur compound metabolic processGO:00067901010.016
organ formationGO:004864530.016
cell divisionGO:00513011680.016
hormone secretionGO:0046879650.016
syncytium formation by plasma membrane fusionGO:000076820.016
long term memoryGO:000761620.016
potassium ion transportGO:0006813620.016
cell substrate adhesionGO:00315891320.016
regulation of protein processingGO:00706131500.016
metencephalon developmentGO:002203720.016
somatic muscle developmentGO:000752510.016
purine nucleoside monophosphate metabolic processGO:00091261860.016
receptor metabolic processGO:0043112810.016
regulation of anatomical structure sizeGO:00900661010.016
negative regulation of protein phosphorylationGO:00019331400.016
endomembrane system organizationGO:00102561960.016
cell part morphogenesisGO:00329901370.016
steroid metabolic processGO:0008202940.016
regulation of vesicle mediated transportGO:00606271300.016
modification dependent macromolecule catabolic processGO:00436322120.016
sequestering of calcium ionGO:0051208170.016
regulation of cell morphogenesisGO:00226041530.016
response to oxygen levelsGO:00704821000.016
purine ribonucleoside monophosphate metabolic processGO:00091671860.016
cell projection morphogenesisGO:00488581290.016
cellular response to abiotic stimulusGO:00712141170.016
chemotaxisGO:00069351570.016
regulation of i kappab kinase nf kappab signalingGO:00431221620.016
somitogenesisGO:000175620.016
actin mediated cell contractionGO:0070252120.015
modification dependent protein catabolic processGO:00199412090.015
negative regulation of immune system processGO:00026831360.015
regulation of protein complex assemblyGO:00432541470.015
cell fate determinationGO:000170930.015
positive regulation of erk1 and erk2 cascadeGO:0070374750.015
ribonucleoside monophosphate metabolic processGO:00091611870.015
hindlimb morphogenesisGO:003513720.015
activation of protein kinase activityGO:0032147900.015
regulation of cytoplasmic transportGO:19036491490.015
regulation of intracellular protein transportGO:00331571230.015
response to steroid hormoneGO:0048545800.015
neuron developmentGO:00486661130.015
negative regulation of proteolysisGO:00458611320.015
covalent chromatin modificationGO:00165692540.015
regulation of ras gtpase activityGO:00323181280.015
regulation of membrane potentialGO:0042391950.015
sensory perception of smellGO:000760820.015
cell type specific apoptotic processGO:00972851250.015
cellular response to histamineGO:007142030.015
ribonucleotide biosynthetic processGO:0009260810.015
sequestering of metal ionGO:0051238240.015
extrinsic apoptotic signaling pathwayGO:00971911190.015
cardiac muscle cell contractionGO:008600340.015
negative regulation of protein processingGO:00109551420.015
positive regulation of proteolysisGO:00458621420.015
regulation of neural precursor cell proliferationGO:200017740.015
taxisGO:00423301570.015
response to bacteriumGO:00096171440.015
response to drugGO:0042493810.015
negative regulation of cell migrationGO:00303361020.015
protein autophosphorylationGO:00467771230.015
ubiquitin dependent protein catabolic processGO:00065112060.015
behavioral response to ethanolGO:004814920.015
cerebellum developmentGO:002154920.015
cellular response to glucocorticoid stimulusGO:007138540.015
small molecule catabolic processGO:0044282920.015
atp metabolic processGO:00460341760.015
leukocyte activationGO:00453211640.015
lung alveolus developmentGO:004828640.015
regulation of cysteine type endopeptidase activityGO:20001161270.015

SLC7A2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.047
musculoskeletal system diseaseDOID:172230.039
inherited metabolic disorderDOID:6552420.038
cancerDOID:1621670.030
disease of cellular proliferationDOID:145661740.030
organ system cancerDOID:00506861640.028
sensory system diseaseDOID:00501552030.025
Human
nervous system diseaseDOID:8634310.025
Human
cardiovascular system diseaseDOID:12871060.024
central nervous system diseaseDOID:3311860.024
muscular diseaseDOID:00800001140.024
muscle tissue diseaseDOID:661130.023
myopathyDOID:4231040.021
urinary system diseaseDOID:18400.019
kidney diseaseDOID:557360.019
eye and adnexa diseaseDOID:14921500.015
Human
eye diseaseDOID:56141490.015
Human
immune system diseaseDOID:29141550.015
neurodegenerative diseaseDOID:12891020.015