Homo sapiens

79 known processes

RFX3

regulatory factor X, 3 (influences HLA class II expression)

(Aliases: bA32F11.1,MGC87155)

RFX3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
amine metabolic processGO:0009308440.093
cellular amino acid metabolic processGO:00065201160.090
regulation of cellular amine metabolic processGO:0033238110.089
regulation of cellular amino acid metabolic processGO:000652160.086
cellular amine metabolic processGO:0044106410.083
regulation of cellular ketone metabolic processGO:0010565500.076
cellular ketone metabolic processGO:0042180800.073
post embryonic developmentGO:000979120.072
positive regulation of cellular amino acid metabolic processGO:004576430.063
positive regulation of cellular amine metabolic processGO:003324070.056
determination of adult lifespanGO:000834020.048
regulation of cell differentiationGO:00455953930.046
Mouse
multicellular organismal agingGO:001025930.046
locomotory behaviorGO:000762610.045
chromatin modificationGO:00165682980.044
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.043
cellular macromolecular complex assemblyGO:00346223240.043
chromatin organizationGO:00063253510.043
organophosphate catabolic processGO:00464344300.043
positive regulation of cellular component organizationGO:00511303760.042
cell morphogenesisGO:00009022960.041
Mouse
female gamete generationGO:000729220.040
purine nucleoside triphosphate metabolic processGO:00091444120.040
positive regulation of catabolic processGO:00098963100.039
nucleoside phosphate catabolic processGO:19012924120.039
small gtpase mediated signal transductionGO:0007264780.039
secretion by cellGO:00329402260.039
Human Mouse
cellular component morphogenesisGO:00329893140.039
Mouse
ras protein signal transductionGO:0007265730.038
memoryGO:000761330.038
purine ribonucleotide catabolic processGO:00091544040.038
ribonucleoside triphosphate metabolic processGO:00091994120.037
cell developmentGO:00484683280.037
Mouse
nucleotide catabolic processGO:00091664080.037
regulation of locomotionGO:00400123290.037
negative regulation of protein metabolic processGO:00512483910.037
purine nucleotide catabolic processGO:00061954050.037
segmentationGO:003528240.037
positive regulation of phosphorylationGO:00423273940.036
regulation of cellular component biogenesisGO:00440872810.036
regulation of cellular component movementGO:00512703340.036
negative regulation of cellular protein metabolic processGO:00322693530.036
regulation of cell cycleGO:00517263930.035
ribonucleotide catabolic processGO:00092614050.035
regulation of secretionGO:00510461940.034
Human Mouse
purine containing compound catabolic processGO:00725234110.034
secretionGO:00469032540.034
Human Mouse
nervous system developmentGO:00073992930.033
Fly
ribonucleoside triphosphate catabolic processGO:00092033910.033
negative regulation of catalytic activityGO:00430863350.033
neuromuscular junction developmentGO:000752830.032
purine ribonucleoside triphosphate metabolic processGO:00092054110.032
purine ribonucleoside metabolic processGO:00461284370.032
oogenesisGO:004847720.032
positive regulation of hydrolase activityGO:00513453310.031
regulation of secretion by cellGO:19035301770.031
Human Mouse
histone modificationGO:00165702510.031
glycosyl compound catabolic processGO:19016584130.031
nucleoside triphosphate metabolic processGO:00091414220.031
purine ribonucleoside catabolic processGO:00461303980.031
negative regulation of cellular amine metabolic processGO:003323930.030
nucleoside triphosphate catabolic processGO:00091433940.030
purine nucleoside catabolic processGO:00061523980.030
regulation of cell migrationGO:00303342890.030
protein ubiquitinationGO:00165673140.030
purine ribonucleoside triphosphate catabolic processGO:00092073910.030
cytoplasmic transportGO:00164823790.030
purine nucleoside triphosphate catabolic processGO:00091463920.029
actin filament based processGO:00300292240.029
cellular response to endogenous stimulusGO:00714953360.029
response to oxygen containing compoundGO:19017003690.029
biological adhesionGO:00226103310.029
nucleoside catabolic processGO:00091644080.029
protein modification by small protein conjugationGO:00324463420.029
mitotic cell cycleGO:00002783260.028
signal transduction by phosphorylationGO:00230142970.028
cell projection organizationGO:00300302520.028
Mouse
regulation of cell motilityGO:20001452990.028
hindbrain developmentGO:003090230.028
regulation of establishment of protein localizationGO:00702012420.028
response to cytokineGO:00340972320.027
ribonucleoside catabolic processGO:00424544060.027
protein acylationGO:00435431380.027
regulation of protein localizationGO:00328802960.027
cytokine productionGO:00018162470.027
cellular macromolecule catabolic processGO:00442653800.026
nitrogen compound transportGO:00717051910.026
Human Mouse
regulation of transferase activityGO:00513383550.026
regulation of cell cycle processGO:00105642660.026
positive regulation of transportGO:00510503360.026
single organism cellular localizationGO:19025803320.026
negative regulation of cellular amino acid metabolic processGO:004576320.026
neuroblast proliferationGO:000740540.026
negative regulation of phosphate metabolic processGO:00459362670.026
regulation of mapk cascadeGO:00434082620.026
negative regulation of phosphorus metabolic processGO:00105632670.025
gtp metabolic processGO:00460392390.025
regulation of intracellular transportGO:00323861950.025
protein catabolic processGO:00301633250.025
positive regulation of cell proliferationGO:00082843010.025
negative regulation of multicellular organismal processGO:00512413170.025
rho protein signal transductionGO:0007266260.025
response to abiotic stimulusGO:00096283360.025
regulation of nucleotide metabolic processGO:00061402690.025
protein localization to organelleGO:00333652800.025
immune responseGO:00069553070.024
intracellular protein transportGO:00068862700.024
covalent chromatin modificationGO:00165692540.024
negative regulation of programmed cell deathGO:00430693210.024
negative regulation of protein modification processGO:00314002000.024
positive regulation of cell differentiationGO:00455972110.024
Mouse
cellular response to dna damage stimulusGO:00069743790.024
positive regulation of protein phosphorylationGO:00019343130.024
vesicle mediated transportGO:00161923710.024
regulation of response to external stimulusGO:00321012220.023
chemical homeostasisGO:00488783060.023
Human
regulation of purine nucleotide metabolic processGO:19005422640.023
mitotic cell cycle processGO:19030472860.023
hemopoiesisGO:00300971800.023
regulation of kinase activityGO:00435493140.023
positive regulation of apoptotic processGO:00430652460.023
blastoderm segmentationGO:000735020.023
mapk cascadeGO:00001652880.023
enzyme linked receptor protein signaling pathwayGO:00071673030.023
regenerationGO:003109940.023
positive regulation of cellular catabolic processGO:00313312840.023
peptidyl lysine modificationGO:00182051440.023
positive regulation of nucleoside metabolic processGO:00459791860.022
regulation of nucleoside metabolic processGO:00091182090.022
anterior posterior axis specificationGO:000994820.022
immune system developmentGO:00025201950.022
positive regulation of developmental processGO:00510943140.022
Mouse
anatomical structure formation involved in morphogenesisGO:00486462840.022
Mouse
interspecies interaction between organismsGO:00444191560.022
positive regulation of nucleotide metabolic processGO:00459812300.022
regulation of cellular response to stressGO:00801352440.022
gtp catabolic processGO:00061842370.022
negative regulation of apoptotic processGO:00430663160.022
negative regulation of developmental processGO:00510932470.022
cation transportGO:00068123310.022
matingGO:000761810.022
photoreceptor cell differentiationGO:004653020.022
guanosine containing compound catabolic processGO:19010692390.022
regulation of protein kinase activityGO:00458592890.022
regulation of anatomical structure morphogenesisGO:00226032860.022
regulation of proteolysisGO:00301622930.021
cell adhesionGO:00071553250.021
guanosine containing compound metabolic processGO:19010682440.021
organelle assemblyGO:00709251760.021
Mouse
transmembrane transportGO:00550853990.021
system processGO:00030083490.021
Fly
regulation of purine nucleotide catabolic processGO:00331212050.021
epithelium developmentGO:00604292270.021
Mouse
adult locomotory behaviorGO:000834410.021
defense responseGO:00069523150.021
metal ion transportGO:00300012720.021
hematopoietic or lymphoid organ developmentGO:00485341860.021
negative regulation of cell deathGO:00605483450.021
inorganic ion transmembrane transportGO:00986602310.021
regulation of mitotic cell cycleGO:00073461890.021
negative regulation of cell proliferationGO:00082852280.021
dephosphorylationGO:00163112090.021
positive regulation of immune system processGO:00026842830.020
cellular protein complex assemblyGO:00436231880.020
negative regulation of hydrolase activityGO:00513461820.020
posttranscriptional regulation of gene expressionGO:00106082130.020
associative learningGO:000830610.020
negative regulation of intracellular signal transductionGO:19025321830.020
spermatid differentiationGO:004851540.020
peptidyl lysine acetylationGO:00183941010.020
negative regulation of cell cycleGO:00457861930.020
regulation of nucleotide catabolic processGO:00308112050.020
membrane organizationGO:00610242920.020
neurotransmitter secretionGO:000726940.020
response to other organismGO:00517072610.019
positive regulation of purine nucleotide metabolic processGO:19005442270.019
leukocyte activationGO:00453211640.019
cell activationGO:00017752130.019
positive regulation of programmed cell deathGO:00430682490.019
cardiovascular system developmentGO:00723582620.019
regulation of synaptic plasticityGO:004816730.019
nerve developmentGO:002167540.019
positive regulation of cellular component biogenesisGO:00440891580.019
morphogenesis of embryonic epitheliumGO:001633140.019
growthGO:00400072020.019
cellular protein catabolic processGO:00442572610.019
cellular response to oxygen containing compoundGO:19017012760.019
i kappab kinase nf kappab signalingGO:00072491660.019
rhythmic behaviorGO:000762220.019
positive regulation of organelle organizationGO:00106381950.019
response to lipidGO:00339932060.019
positive regulation of locomotionGO:00400171860.018
positive regulation of nucleotide catabolic processGO:00308131850.018
single organism membrane organizationGO:00448022680.018
regulation of ras protein signal transductionGO:00465781550.018
regulation of gtp catabolic processGO:00331241800.018
protein maturationGO:00516042330.018
amide transportGO:0042886760.018
Human Mouse
inner ear morphogenesisGO:004247240.018
cell projection morphogenesisGO:00488581290.018
Mouse
negative regulation of cellular component organizationGO:00511292350.018
regulation of cell morphogenesisGO:00226041530.018
protein processingGO:00164852260.018
lipid metabolic processGO:00066293810.018
positive regulation of cell deathGO:00109422630.018
cellular response to cytokine stimulusGO:00713451810.018
actin cytoskeleton organizationGO:00300362070.018
spermatid developmentGO:000728640.018
apoptotic signaling pathwayGO:00971902680.018
ion transmembrane transportGO:00342203380.018
negative regulation of phosphorylationGO:00423261740.018
positive regulation of gtp catabolic processGO:00331261660.018
oocyte developmentGO:004859910.018
epithelium migrationGO:00901321190.017
hormone secretionGO:0046879650.017
Human Mouse
compound eye developmentGO:004874910.017
protein targetingGO:00066051870.017
protein acetylationGO:00064731160.017
cellular lipid metabolic processGO:00442553030.017
response to organic cyclic compoundGO:00140702040.017
metencephalon developmentGO:002203720.017
regulation of protein transportGO:00512232130.017
positive regulation of purine nucleotide catabolic processGO:00331231850.017
neurogenesisGO:00220081690.017
neurological system processGO:00508771630.017
Fly
negative regulation of transportGO:00510511760.017
regulation of neurotransmitter secretionGO:004692830.017
rna processingGO:00063962550.017
regulation of cytokine productionGO:00018172320.017
protein autophosphorylationGO:00467771230.017
cilium morphogenesisGO:0060271750.017
Mouse
lung alveolus developmentGO:004828640.017
regulation of small gtpase mediated signal transductionGO:00510561560.017
cell projection assemblyGO:00300311260.017
Mouse
peptide transportGO:0015833740.017
Human Mouse
regulation of growthGO:00400081650.017
regulation of sequence specific dna binding transcription factor activityGO:00510902110.017
oocyte differentiationGO:000999420.017
inorganic cation transmembrane transportGO:00986621940.017
cation transmembrane transportGO:00986552380.017
cell substrate adhesionGO:00315891320.017
regulation of neural precursor cell proliferationGO:200017740.017
microtubule based processGO:00070172100.017
Mouse
positive regulation of protein transportGO:00512221350.016
regulation of protein catabolic processGO:00421761550.016
motor neuron axon guidanceGO:000804520.016
negative regulation of cell differentiationGO:00455961710.016
neuron differentiationGO:00301821380.016
regulation of protein serine threonine kinase activityGO:00719001790.016
cell fate determinationGO:000170930.016
regulation of vesicle mediated transportGO:00606271300.016
mitotic cell cycle phase transitionGO:00447721620.016
positive regulation of gtpase activityGO:00435471660.016
establishment of protein localization to organelleGO:00725941720.016
regulation of ras gtpase activityGO:00323181280.016
regulation of peptidase activityGO:00525471800.016
peripheral nervous system developmentGO:000742220.016
regulation of cytoskeleton organizationGO:00514931770.016
myeloid cell differentiationGO:00300991170.016
regulation of multi organism processGO:00439001570.016
ameboidal type cell migrationGO:00016671350.016
regulation of immune responseGO:00507762010.016
tripartite regional subdivisionGO:000735120.016
positive regulation of cellular component movementGO:00512721810.016
positive regulation of cell migrationGO:00303351720.016
negative regulation of synaptic transmissionGO:005080520.016
cell cell signalingGO:00072671550.016
Human Mouse
somatic stem cell maintenanceGO:003501940.016
peptidyl tyrosine phosphorylationGO:00181081700.016
cilium assemblyGO:0042384630.016
Mouse
response to external biotic stimulusGO:00432072610.016
cilium organizationGO:0044782680.016
Mouse
circulatory system developmentGO:00723592620.016
regulation of wnt signaling pathwayGO:00301111230.016
negative regulation of cellular component movementGO:00512711060.016
release of cytoplasmic sequestered nf kappabGO:000858840.016
negative regulation of gliogenesisGO:001401430.015
reactive oxygen species biosynthetic processGO:190340940.015
maintenance of locationGO:00512351120.015
cellular response to growth factor stimulusGO:00713631970.015
response to woundingGO:00096111680.015
proteolysis involved in cellular protein catabolic processGO:00516032440.015
reactive nitrogen species metabolic processGO:200105730.015
peptide secretionGO:0002790510.015
Human Mouse
response to growth factorGO:00708482050.015
positive regulation of ras gtpase activityGO:00323201170.015
peptidyl tyrosine modificationGO:00182121700.015
response to biotic stimulusGO:00096072760.015
generation of neuronsGO:00486991520.015
nuclear transportGO:00511691790.015
anterior posterior axis specification embryoGO:000859520.015
visual behaviorGO:000763220.015
regulation of gtpase activityGO:00430871800.015
positive regulation of synaptic transmissionGO:005080640.015
positive regulation of transferase activityGO:00513472270.015
blood vessel developmentGO:00015681720.015
circadian behaviorGO:004851220.015
cell cycle phase transitionGO:00447701730.015
cranial nerve developmentGO:002154540.015
multi organism cellular processGO:00447641560.015
regulation of cell adhesionGO:00301551660.015
regulation of endopeptidase activityGO:00525481700.015
viral life cycleGO:00190581320.015
divalent inorganic cation transportGO:00725111580.015
signal releaseGO:0023061700.015
Human Mouse
regulation of protein complex assemblyGO:00432541470.015
positive regulation of protein kinase activityGO:00458601900.015
tissue regenerationGO:004224630.015
cellular chemical homeostasisGO:00550821800.015
forebrain generation of neuronsGO:002187230.015
cell part morphogenesisGO:00329901370.015
Mouse
regulation of hormone levelsGO:00108171250.014
Human Mouse
regulation of glial cell proliferationGO:006025140.014
innate immune responseGO:00450871780.014
sex determinationGO:000753030.014
regulation of cytoplasmic transportGO:19036491490.014
protein oligomerizationGO:00512591730.014
cell growthGO:00160491600.014
reactive oxygen species metabolic processGO:0072593750.014
symbiosis encompassing mutualism through parasitismGO:00444031560.014
cardiac muscle cell contractionGO:008600340.014
cation homeostasisGO:00550801890.014
wnt signaling pathwayGO:00160551560.014
positive regulation of cell cycleGO:00457871400.014
central nervous system developmentGO:00074171230.014
regulation of peptide transportGO:0090087620.014
Human Mouse
peptidyl serine phosphorylationGO:00181051010.014
cerebellum developmentGO:002154920.014
mrna metabolic processGO:00160711750.014
histone acetylationGO:0016573930.014
negative regulation of protein phosphorylationGO:00019331400.014
regulation of i kappab kinase nf kappab signalingGO:00431221620.014
cellular homeostasisGO:00197251960.014
regulation of epithelial cell migrationGO:0010632930.014
carbohydrate derivative biosynthetic processGO:19011372070.014
regulation of dna metabolic processGO:00510521530.014
carbohydrate metabolic processGO:00059752070.014
positive regulation of mapk cascadeGO:00434101900.014
negative regulation of locomotionGO:00400131180.014
regulation of reactive oxygen species biosynthetic processGO:190342630.014
somitogenesisGO:000175620.013
peptide hormone secretionGO:0030072500.013
Human Mouse
epithelial cell migrationGO:00106311190.013
regulation of cell developmentGO:00602841610.013
Mouse
chemotaxisGO:00069351570.013
hormone transportGO:0009914680.013
Human Mouse
tissue migrationGO:00901301190.013
cellular response to lipidGO:00713961270.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.013
regulation of protein maturationGO:19033171500.013
forebrain neuron differentiationGO:002187930.013
ubiquitin dependent protein catabolic processGO:00065112060.013
regulation of intracellular protein transportGO:00331571230.013
actin filament organizationGO:00070151280.013
negative regulation of cell cycle processGO:00109481210.013
endomembrane system organizationGO:00102561960.013
proteasomal protein catabolic processGO:00104981760.013
sequestering of metal ionGO:0051238240.013
negative regulation of cell migrationGO:00303361020.013
sequestering of calcium ionGO:0051208170.013
nucleocytoplasmic transportGO:00069131760.013
positive regulation of kinase activityGO:00336742040.013
negative regulation of immune system processGO:00026831360.013
negative regulation of cell motilityGO:20001461040.013
syncytium formation by plasma membrane fusionGO:000076820.013
neuron developmentGO:00486661130.013
regulation of ion transportGO:00432691890.013
regulation of cell growthGO:00015581350.013
cell cycle checkpointGO:00000751170.013
ion homeostasisGO:00508012300.013
single organism carbohydrate metabolic processGO:00447231930.013
purine nucleoside monophosphate metabolic processGO:00091261860.013
peptidyl serine modificationGO:00182091060.013
modification dependent protein catabolic processGO:00199412090.013
cellular component assembly involved in morphogenesisGO:0010927730.013
Mouse
organophosphate biosynthetic processGO:00904071630.013
purine ribonucleoside monophosphate metabolic processGO:00091671860.013
endocytosisGO:00068971590.013
response to axon injuryGO:004867810.013
actin filament based movementGO:0030048170.013
divalent metal ion transportGO:00708381520.013
cell divisionGO:00513011680.013
cell morphogenesis involved in differentiationGO:00009041440.013
male genitalia developmentGO:003053910.013
negative regulation of proteolysisGO:00458611320.013
morphogenesis of a polarized epitheliumGO:000173830.013
organonitrogen compound biosynthetic processGO:19015662000.013
internal protein amino acid acetylationGO:00064751010.013
negative regulation of transferase activityGO:00513481240.012
anion transportGO:00068201610.012
positive regulation of immune responseGO:00507781590.012
modification dependent macromolecule catabolic processGO:00436322120.012
regulation of cell cycle phase transitionGO:19019871260.012
response to nitrogen compoundGO:19016981840.012
regulation of cell activationGO:00508651250.012
regulation of protein processingGO:00706131500.012
protein localization to nucleusGO:00345041360.012
lipid biosynthetic processGO:00086101770.012
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.012
nucleoside monophosphate metabolic processGO:00091231910.012
angiogenesisGO:00015251470.012
negative regulation of protein maturationGO:19033181420.012
endodermal cell fate specificationGO:000171440.012
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.012
ribonucleoside monophosphate metabolic processGO:00091611870.012
cellular response to glucocorticoid stimulusGO:007138540.012
neural tube formationGO:000184130.012
single organism cell adhesionGO:00986021790.012
long term memoryGO:000761620.012
vasculature developmentGO:00019441810.012
sensory perception of painGO:001923340.012
endosomal transportGO:00161971290.012
ossificationGO:00015031210.012
response to radiationGO:00093141510.012
positive regulation of cell motilityGO:20001471770.012
actin mediated cell contractionGO:0070252120.012
immune effector processGO:00022521590.012
embryonic epithelial tube formationGO:000183840.012
blood vessel morphogenesisGO:00485141620.012
viral processGO:00160321460.012
microtubule cytoskeleton organizationGO:00002261760.012
visual learningGO:000854210.012
organ formationGO:004864530.012
canonical wnt signaling pathwayGO:00600701160.012
negative regulation of protein processingGO:00109551420.012
regulation of protein stabilityGO:0031647870.012
response to fungusGO:000962040.012
regulation of cell divisionGO:00513021160.012
atp metabolic processGO:00460341760.012
internal peptidyl lysine acetylationGO:0018393970.012
lens development in camera type eyeGO:000208820.012
positive regulation of cell cycle processGO:00900681060.012
endodermal cell fate commitmentGO:000171140.012
regulation of cysteine type endopeptidase activityGO:20001161270.012
regulation of actin filament based processGO:00329701410.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
spinal cord developmentGO:002151040.011
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.011
regulation of actin cytoskeleton organizationGO:00329561160.011
regulation of homeostatic processGO:00328441210.011
behaviorGO:00076101120.011
reproductive processGO:00224141060.011
regulation of leukocyte activationGO:00026941150.011
macromolecule methylationGO:0043414970.011
regulation of defense responseGO:00313471540.011
calcium ion transportGO:00068161470.011
embryonic eye morphogenesisGO:004804820.011
head developmentGO:00603221080.011
negative regulation of organelle organizationGO:00106391260.011
metal ion homeostasisGO:00550651690.011
protein importGO:00170381300.011
regulation of mitotic cell cycle phase transitionGO:19019901180.011
salivary gland morphogenesisGO:000743540.011
dna repairGO:00062811980.011
cellular metal ion homeostasisGO:00068751460.011
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.011
regulation of dephosphorylationGO:0035303960.011
oxidation reduction processGO:00551143960.011
single organismal cell cell adhesionGO:00163371480.011
cellular cation homeostasisGO:00300031630.011
regulation of neuroblast proliferationGO:190269230.011
protein localization to membraneGO:00726571600.011
thymus developmentGO:004853830.011
stem cell divisionGO:001714520.011
epithelial cell proliferationGO:00506731280.011
regulation of bindingGO:00510981110.011
regulation of male gonad developmentGO:200001840.011
regulation of viral processGO:00507921030.011
negative regulation of protein kinase activityGO:0006469980.011
negative regulation of wnt signaling pathwayGO:0030178690.011
regulation of transcription from rna polymerase ii promoter mitoticGO:004602110.011
dna conformation changeGO:00711031130.011
glycoprotein metabolic processGO:00091001100.011
taxisGO:00423301570.011
methylationGO:00322591060.011
neural crest cell developmentGO:001403230.011

RFX3 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:00501552030.029
nervous system diseaseDOID:8634310.029
eye diseaseDOID:56141490.025
eye and adnexa diseaseDOID:14921500.025
central nervous system diseaseDOID:3311860.023
disease of cellular proliferationDOID:145661740.023
organ system cancerDOID:00506861640.023
cancerDOID:1621670.023
disease of metabolismDOID:00146672950.023
retinal diseaseDOID:56791180.016
immune system diseaseDOID:29141550.015
inherited metabolic disorderDOID:6552420.015
musculoskeletal system diseaseDOID:172230.014
connective tissue diseaseDOID:651090.014
neurodegenerative diseaseDOID:12891020.013
bone diseaseDOID:0080001880.013
retinal degenerationDOID:8466890.012