Homo sapiens

7 known processes

GGH

gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)

(Aliases: GH)

GGH biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
glycosyl compound catabolic processGO:19016584130.190
negative regulation of methylation dependent chromatin silencingGO:009031020.185
microtubule based movementGO:0007018320.176
purine ribonucleoside metabolic processGO:00461284370.139
cytidine metabolic processGO:004608770.132
stem cell divisionGO:001714520.126
post embryonic developmentGO:000979120.119
clearance of foreign intracellular dna by conversion of dna cytidine to uridineGO:004435610.112
organophosphate biosynthetic processGO:00904071630.100
secretionGO:00469032540.095
regulation of transferase activityGO:00513383550.095
regulation of cellular component movementGO:00512703340.092
cellular lipid metabolic processGO:00442553030.091
cellular ketone metabolic processGO:0042180800.082
ribonucleotide catabolic processGO:00092614050.081
response to biotic stimulusGO:00096072760.073
cytidine deaminationGO:000997270.072
asymmetric neuroblast divisionGO:005505910.072
neuroblast proliferationGO:000740540.072
somatic stem cell divisionGO:004810310.072
purine nucleoside catabolic processGO:00061523980.071
regulation of proteolysisGO:00301622930.068
purine ribonucleoside monophosphate metabolic processGO:00091671860.067
cellular amino acid metabolic processGO:00065201160.066
organophosphate catabolic processGO:00464344300.066
nucleotide biosynthetic processGO:00091651090.066
multicellular organismal agingGO:001025930.066
nervous system developmentGO:00073992930.064
small gtpase mediated signal transductionGO:0007264780.063
neuronal stem cell divisionGO:003644510.062
maintenance of locationGO:00512351120.062
nucleoside catabolic processGO:00091644080.062
purine nucleotide biosynthetic processGO:0006164840.061
regulation of cellular amine metabolic processGO:0033238110.061
microtubule organizing center organizationGO:0031023620.061
cdc42 protein signal transductionGO:003248840.060
carbohydrate derivative biosynthetic processGO:19011372070.060
cellular amine metabolic processGO:0044106410.059
spermatid differentiationGO:004851540.058
regulation of kinase activityGO:00435493140.058
positive regulation of catabolic processGO:00098963100.057
mitotic cell cycleGO:00002783260.056
cellular protein complex assemblyGO:00436231880.056
cell fate determinationGO:000170930.056
purine ribonucleoside catabolic processGO:00461303980.056
cytidine catabolic processGO:000621670.055
positive regulation of protein kinase activityGO:00458601900.054
negative regulation of catalytic activityGO:00430863350.054
positive regulation of phosphorylationGO:00423273940.053
cell developmentGO:00484683280.053
regulation of cellular response to stressGO:00801352440.052
nucleoside phosphate catabolic processGO:19012924120.052
immune responseGO:00069553070.052
positive regulation of programmed cell deathGO:00430682490.051
purine nucleoside triphosphate metabolic processGO:00091444120.050
negative regulation of organelle organizationGO:00106391260.050
ribonucleoside monophosphate catabolic processGO:00091581580.048
positive regulation of protein phosphorylationGO:00019343130.048
neuroblast divisionGO:005505710.048
cellular response to oxidative stressGO:0034599850.048
response to oxidative stressGO:00069791210.048
purine nucleoside monophosphate metabolic processGO:00091261860.048
determination of adult lifespanGO:000834020.047
carbohydrate metabolic processGO:00059752070.046
small molecule biosynthetic processGO:00442831570.046
guanosine containing compound metabolic processGO:19010682440.046
response to external biotic stimulusGO:00432072610.046
regulation of methylation dependent chromatin silencingGO:009030830.045
positive regulation of cell proliferationGO:00082843010.045
ras protein signal transductionGO:0007265730.045
organonitrogen compound biosynthetic processGO:19015662000.044
rho protein signal transductionGO:0007266260.043
regenerationGO:003109940.043
response to abiotic stimulusGO:00096283360.042
wnt signaling pathwayGO:00160551560.041
regulation of cell differentiationGO:00455953930.041
neuron differentiationGO:00301821380.041
positive regulation of kinase activityGO:00336742040.040
locomotory behaviorGO:000762610.039
spindle elongationGO:005123140.039
negative regulation of protein metabolic processGO:00512483910.039
lipid metabolic processGO:00066293810.039
positive regulation of developmental processGO:00510943140.038
positive regulation of cell differentiationGO:00455972110.038
system processGO:00030083490.038
regulation of locomotionGO:00400123290.038
hemopoiesisGO:00300971800.038
negative regulation of phosphate metabolic processGO:00459362670.037
ribonucleoside catabolic processGO:00424544060.037
regulation of response to external stimulusGO:00321012220.037
regulation of protein processingGO:00706131500.037
nucleoside triphosphate metabolic processGO:00091414220.037
purine containing compound biosynthetic processGO:0072522880.036
negative regulation of cellular component organizationGO:00511292350.036
purine nucleoside triphosphate catabolic processGO:00091463920.036
clearance of foreign intracellular dnaGO:004435510.036
biological adhesionGO:00226103310.036
nuclear migrationGO:000709710.035
regulation of cellular amino acid metabolic processGO:000652160.035
cellular homeostasisGO:00197251960.035
purine containing compound catabolic processGO:00725234110.035
purine nucleotide catabolic processGO:00061954050.035
alcohol metabolic processGO:00060661140.034
regulation of cellular ketone metabolic processGO:0010565500.034
wound healingGO:00420601150.034
regulation of meiotic cell cycleGO:005144540.034
cellular response to dna damage stimulusGO:00069743790.034
innate immune responseGO:00450871780.033
ribonucleoside triphosphate catabolic processGO:00092033910.033
positive regulation of hydrolase activityGO:00513453310.033
positive regulation of nucleoside metabolic processGO:00459791860.033
nucleotide catabolic processGO:00091664080.033
amine metabolic processGO:0009308440.032
negative regulation of cellular protein metabolic processGO:00322693530.032
nucleus localizationGO:005164710.032
ribonucleoside triphosphate metabolic processGO:00091994120.032
positive regulation of cellular amino acid metabolic processGO:004576430.032
growthGO:00400072020.032
ribonucleoside monophosphate metabolic processGO:00091611870.031
cellular response to lipidGO:00713961270.031
single organism carbohydrate metabolic processGO:00447231930.031
response to other organismGO:00517072610.031
cellular response to biotic stimulusGO:0071216710.030
glycerophospholipid metabolic processGO:0006650840.030
purine ribonucleoside triphosphate metabolic processGO:00092054110.029
negative regulation of cell deathGO:00605483450.029
urate metabolic processGO:0046415110.029
reproductive processGO:00224141060.029
fear responseGO:004259600.029
cell projection organizationGO:00300302520.029
response to activityGO:001482300.029
response to bacteriumGO:00096171440.029
spermatid developmentGO:000728640.029
hindbrain developmentGO:003090230.029
positive regulation of purine nucleotide catabolic processGO:00331231850.029
cellular macromolecule catabolic processGO:00442653800.029
immune system developmentGO:00025201950.029
oxidation reduction processGO:00551143960.029
regulation of membrane potentialGO:0042391950.029
positive regulation of nucleotide metabolic processGO:00459812300.028
negative regulation of transferase activityGO:00513481240.028
gtp metabolic processGO:00460392390.028
signal transduction by phosphorylationGO:00230142970.028
response to woundingGO:00096111680.028
negative regulation of phosphorus metabolic processGO:00105632670.028
response to lipidGO:00339932060.028
defense responseGO:00069523150.027
cell morphogenesisGO:00009022960.027
glycerolipid metabolic processGO:00464861070.027
blood vessel morphogenesisGO:00485141620.027
mapk cascadeGO:00001652880.027
viral processGO:00160321460.027
protein homooligomerizationGO:00512601000.027
regulation of cell cycleGO:00517263930.027
positive regulation of nucleotide catabolic processGO:00308131850.027
protein maturationGO:00516042330.026
positive regulation of transportGO:00510503360.026
female gamete generationGO:000729220.026
cellular response to endogenous stimulusGO:00714953360.026
positive regulation of cellular catabolic processGO:00313312840.026
microtubule polymerization or depolymerizationGO:0031109370.026
positive regulation of cell deathGO:00109422630.026
regulation of apoptotic signaling pathwayGO:20012331750.026
protein processingGO:00164852260.026
regulation of protein localizationGO:00328802960.026
regulation of cardiac muscle tissue growthGO:005502140.026
regulation of peptidase activityGO:00525471800.025
positive regulation of cellular amine metabolic processGO:003324070.025
interspecies interaction between organismsGO:00444191560.025
dna repairGO:00062811980.025
cell chemotaxisGO:00603261120.025
glycoprotein metabolic processGO:00091001100.025
regulation of nucleotide metabolic processGO:00061402690.025
cellular component morphogenesisGO:00329893140.025
regulation of wnt signaling pathwayGO:00301111230.024
neuron developmentGO:00486661130.024
coenzyme metabolic processGO:0006732650.024
lipid biosynthetic processGO:00086101770.024
tissue regenerationGO:004224630.024
regulation of dna metabolic processGO:00510521530.024
circulatory system developmentGO:00723592620.023
proteasomal protein catabolic processGO:00104981760.023
central nervous system developmentGO:00074171230.023
cellular response to external stimulusGO:00714961110.023
negative regulation of phosphorylationGO:00423261740.023
regulation of cellular component biogenesisGO:00440872810.023
purine ribonucleoside triphosphate catabolic processGO:00092073910.023
negative regulation of programmed cell deathGO:00430693210.023
cofactor metabolic processGO:0051186870.023
anion transportGO:00068201610.023
myeloid cell differentiationGO:00300991170.023
dna replicationGO:00062601160.023
regulation of small gtpase mediated signal transductionGO:00510561560.023
negative regulation of proteolysisGO:00458611320.022
nucleoside triphosphate catabolic processGO:00091433940.022
regulation of cell cycle processGO:00105642660.022
peptidyl tyrosine phosphorylationGO:00181081700.022
dephosphorylationGO:00163112090.022
negative regulation of intracellular signal transductionGO:19025321830.022
positive regulation of apoptotic processGO:00430652460.022
fatty acid metabolic processGO:00066311150.022
protein catabolic processGO:00301633250.022
response to inorganic substanceGO:00100351270.022
negative regulation of mitotic anaphase promoting complex activityGO:006056440.022
secretion by cellGO:00329402260.022
symbiosis encompassing mutualism through parasitismGO:00444031560.021
cytokinesisGO:0000910960.021
generation of neuronsGO:00486991520.021
cell projection morphogenesisGO:00488581290.021
cardiovascular system developmentGO:00723582620.021
cellular response to hydrogen peroxideGO:0070301370.021
multi organism cellular processGO:00447641560.021
dna recombinationGO:0006310770.021
regulation of protein serine threonine kinase activityGO:00719001790.021
hematopoietic or lymphoid organ developmentGO:00485341860.021
dna cytosine deaminationGO:007038350.020
cellular macromolecular complex assemblyGO:00346223240.020
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.020
positive regulation of gtp catabolic processGO:00331261660.020
viral life cycleGO:00190581320.020
neurological system processGO:00508771630.020
regulation of multi organism processGO:00439001570.020
regulation of mapk cascadeGO:00434082620.020
negative regulation of microtubule polymerization or depolymerizationGO:0031111170.020
regulation of purine nucleotide metabolic processGO:19005422640.020
regulation of i kappab kinase nf kappab signalingGO:00431221620.020
reproductive system developmentGO:0061458560.020
chemical homeostasisGO:00488783060.020
regulation of nucleoside metabolic processGO:00091182090.019
cell death in response to oxidative stressGO:0036473290.019
regulation of endopeptidase activityGO:00525481700.019
response to virusGO:00096151260.019
meiotic chromosome segregationGO:004513240.019
regulation of cell migrationGO:00303342890.019
chromosome segregationGO:00070591140.019
regulation of ras protein signal transductionGO:00465781550.019
developmental process involved in reproductionGO:0003006660.019
oocyte developmentGO:004859910.018
positive regulation of cdc42 gtpase activityGO:004308960.018
regulation of mitotic cell cycle phase transitionGO:19019901180.018
gmp metabolic processGO:004603740.018
positive regulation of proteolysisGO:00458621420.018
nucleoside phosphate biosynthetic processGO:19012931090.018
multicellular organismal response to stressGO:003355510.018
negative regulation of protein complex assemblyGO:0031333430.018
protein depolymerizationGO:0051261300.018
positive regulation of protein serine threonine kinase activityGO:00719021190.018
regulation of response to dna damage stimulusGO:2001020940.018
single organism reproductive processGO:0044702980.018
regulation of protein complex assemblyGO:00432541470.017
epithelial cell proliferationGO:00506731280.017
response to hydrogen peroxideGO:0042542400.017
gonad developmentGO:0008406340.017
glycoprotein biosynthetic processGO:0009101910.017
epithelial cell differentiationGO:00308551410.017
neurogenesisGO:00220081690.017
vesicle mediated transportGO:00161923710.017
glycosylationGO:0070085710.017
actin filament based processGO:00300292240.017
peptidyl serine modificationGO:00182091060.017
positive regulation of neural precursor cell proliferationGO:200017920.017
positive regulation of purine nucleotide metabolic processGO:19005442270.017
regulation of meiosisGO:004002030.017
enzyme linked receptor protein signaling pathwayGO:00071673030.017
regulation of protein transportGO:00512232130.017
protein polyubiquitinationGO:00002091100.017
regulation of anatomical structure morphogenesisGO:00226032860.017
stress activated protein kinase signaling cascadeGO:0031098940.016
regulation of gtp catabolic processGO:00331241800.016
nucleoside monophosphate metabolic processGO:00091231910.016
taxisGO:00423301570.016
negative regulation of ubiquitin protein ligase activity involved in mitotic cell cycleGO:005143640.016
response to oxygen containing compoundGO:19017003690.016
positive regulation of protein transportGO:00512221350.016
mitotic nuclear divisionGO:00070671190.016
cellular response to molecule of bacterial originGO:0071219620.016
protein oligomerizationGO:00512591730.016
negative regulation of protein modification processGO:00314002000.016
oocyte maturationGO:000155610.016
erythrocyte homeostasisGO:0034101310.016
organic hydroxy compound metabolic processGO:19016151470.016
cellular response to reactive oxygen speciesGO:0034614500.016
reproductive structure developmentGO:0048608550.016
positive regulation of map kinase activityGO:0043406800.016
protein glycosylationGO:0006486620.016
anatomical structure homeostasisGO:00602491000.016
negative regulation of hydrolase activityGO:00513461820.015
phototransductionGO:000760230.015
establishment of organelle localizationGO:0051656590.015
adult locomotory behaviorGO:000834410.015
gtp catabolic processGO:00061842370.015
positive regulation of cysteine type endopeptidase activityGO:2001056790.015
macromolecule glycosylationGO:0043413630.015
positive regulation of cell developmentGO:0010720920.015
response to molecule of bacterial originGO:0002237820.015
endocytosisGO:00068971590.015
inflammatory responseGO:0006954790.015
apoptotic signaling pathwayGO:00971902680.015
regulation of cell motilityGO:20001452990.015
cell substrate adhesionGO:00315891320.015
single organism cell adhesionGO:00986021790.015
negative regulation of transcription initiation from rna polymerase ii promoterGO:006063330.015
cellular response to oxygen containing compoundGO:19017012760.015
response to metal ionGO:0010038840.015
negative regulation of apoptotic signaling pathwayGO:2001234970.015
atp catabolic processGO:00062001570.015
regulation of epithelial cell proliferationGO:00506781130.015
regulation of microtubule polymerization or depolymerizationGO:0031110270.015
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.015
nucleoside monophosphate catabolic processGO:00091251590.015
regulation of cysteine type endopeptidase activityGO:20001161270.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.014
axon cargo transportGO:000808820.014
morphogenesis of embryonic epitheliumGO:001633140.014
regulation of gtpase activityGO:00430871800.014
negative regulation of multicellular organismal processGO:00512413170.014
peripheral nervous system developmentGO:000742220.014
developmental growthGO:0048589480.014
v d j recombinationGO:003315130.014
regulation of rho protein signal transductionGO:0035023790.014
regulation of sequence specific dna binding transcription factor activityGO:00510902110.014
metal ion transportGO:00300012720.014
negative regulation of protein processingGO:00109551420.014
cytoskeleton dependent intracellular transportGO:0030705210.014
guanosine containing compound catabolic processGO:19010692390.014
canonical wnt signaling pathwayGO:00600701160.014
positive regulation of cellular component organizationGO:00511303760.014
negative regulation of protein ubiquitinationGO:0031397350.014
cell part morphogenesisGO:00329901370.014
positive regulation of transferase activityGO:00513472270.014
regulation of intracellular protein transportGO:00331571230.014
response to light stimulusGO:0009416870.014
cell adhesionGO:00071553250.014
protein tetramerizationGO:0051262470.014
purine ribonucleotide catabolic processGO:00091544040.014
nuclear divisionGO:00002801280.014
cell morphogenesis involved in differentiationGO:00009041440.014
positive regulation of intracellular transportGO:00323881040.013
peptidyl serine phosphorylationGO:00181051010.013
reproductionGO:0000003630.013
negative regulation of protein maturationGO:19033181420.013
negative regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:001705520.013
cell type specific apoptotic processGO:00972851250.013
mitochondrion organizationGO:00070051560.013
oogenesisGO:004847720.013
embryo developmentGO:00097901230.013
proteolysis involved in cellular protein catabolic processGO:00516032440.013
purine nucleoside monophosphate catabolic processGO:00091281580.013
liposaccharide metabolic processGO:1903509270.013
autophagyGO:0006914880.013
regulation of viral processGO:00507921030.013
response to reactive oxygen speciesGO:0000302610.013
regulation of cardiac muscle cell proliferationGO:006004340.013
nuclear transportGO:00511691790.013
inorganic ion transmembrane transportGO:00986602310.013
membrane lipid metabolic processGO:0006643530.013
regulation of heart growthGO:006042040.013
angiogenesisGO:00015251470.013
purine ribonucleoside monophosphate catabolic processGO:00091691580.013
regulation of nucleocytoplasmic transportGO:0046822980.013
negative regulation of chromosome organizationGO:2001251480.013
regulation of intracellular transportGO:00323861950.013
double strand break repairGO:00063021010.012
response to organic cyclic compoundGO:00140702040.012
regulation of purine nucleotide catabolic processGO:00331212050.012
defense response to other organismGO:00985421290.012
positive regulation of cellular component movementGO:00512721810.012
regulation of protein maturationGO:19033171500.012
base conversion or substitution editingGO:001655340.012
embryonic epithelial tube formationGO:000183840.012
cellular chemical homeostasisGO:00550821800.012
cellular response to iron ionGO:007128110.012
negative regulation of apoptotic processGO:00430663160.012
chromatin organizationGO:00063253510.012
primary neural tube formationGO:001402030.012
positive regulation of cell cycleGO:00457871400.012
negative regulation of cellular amine metabolic processGO:003323930.012
sex differentiationGO:0007548450.012
response to axon injuryGO:004867810.012
regulation of ras gtpase activityGO:00323181280.012
brain morphogenesisGO:004885410.012
covalent chromatin modificationGO:00165692540.012
cellular response to hormone stimulusGO:00328701250.012
negative regulation of cell proliferationGO:00082852280.012
ribonucleoside biosynthetic processGO:0042455250.012
positive regulation of peptidase activityGO:0010952880.012
ubiquitin dependent protein catabolic processGO:00065112060.012
anatomical structure formation involved in morphogenesisGO:00486462840.012
negative regulation of cellular amino acid metabolic processGO:004576320.012
protein targetingGO:00066051870.012
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.012
negative regulation of multi organism processGO:0043901920.011
positive regulation of cardiac muscle cell proliferationGO:006004520.011
regulation of homeostatic processGO:00328441210.011
protein localization to nucleusGO:00345041360.011
cell cycle checkpointGO:00000751170.011
regulation of growthGO:00400081650.011
regulation of rho gtpase activityGO:0032319660.011
positive regulation of organ growthGO:004662220.011
positive regulation of cytoplasmic transportGO:1903651820.011
peptidyl tyrosine modificationGO:00182121700.011
regulation of cytoplasmic transportGO:19036491490.011
organelle assemblyGO:00709251760.011
regulation of protein ubiquitinationGO:0031396950.011
regulation of cell adhesionGO:00301551660.011
regulation of nucleotide catabolic processGO:00308112050.011
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.011
response to steroid hormoneGO:0048545800.011
cell growthGO:00160491600.011
cellular protein catabolic processGO:00442572610.011
negative regulation of cell cycleGO:00457861930.011
phospholipid metabolic processGO:0006644990.011
response to starvationGO:0042594590.011
protein ubiquitinationGO:00165673140.011
regulation of protein kinase activityGO:00458592890.011
i kappab kinase nf kappab signalingGO:00072491660.011
regulation of canonical wnt signaling pathwayGO:0060828880.011
response to calcium ionGO:0051592460.011
response to oxygen levelsGO:00704821000.011
regulation of neural precursor cell proliferationGO:200017740.011
rna polymerase ii transcriptional preinitiation complex assemblyGO:005112340.011
organelle fissionGO:00482851490.011
forebrain generation of neuronsGO:002187230.011
cellular metal ion homeostasisGO:00068751460.011
positive regulation of immune system processGO:00026842830.010
positive regulation of ras gtpase activityGO:00323201170.010
actin mediated cell contractionGO:0070252120.010
establishment of nucleus localizationGO:004002310.010
endosomal transportGO:00161971290.010
glycerophospholipid biosynthetic processGO:0046474400.010
single organism cellular localizationGO:19025803320.010
male sex differentiationGO:0046661250.010
blood vessel developmentGO:00015681720.010
regulation of attachment of spindle microtubules to kinetochoreGO:005198890.010
ion transmembrane transportGO:00342203380.010
negative regulation of protein modification by small protein conjugation or removalGO:1903321410.010
inflammatory response to antigenic stimulusGO:000243740.010
multi organism reproductive processGO:0044703540.010

GGH disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:6552420.761
disease of metabolismDOID:00146672950.761
carbohydrate metabolic disorderDOID:2978550.053
congenital disorder of glycosylationDOID:5212260.053
disease of cellular proliferationDOID:145661740.026
cancerDOID:1621670.020
organ system cancerDOID:00506861640.020
amino acid metabolic disorderDOID:9252500.013
immune system diseaseDOID:29141550.012
hematopoietic system diseaseDOID:741000.012