Homo sapiens

292 known processes

RIPK1

receptor (TNFRSF)-interacting serine-threonine kinase 1

(Aliases: RIP1,RIP,FLJ39204)

RIPK1 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of i kappab kinase nf kappab signalingGO:00431231321.000
regulation of i kappab kinase nf kappab signalingGO:00431221621.000
i kappab kinase nf kappab signalingGO:00072491661.000
programmed necrotic cell deathGO:0097300181.000
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238261.000
extrinsic apoptotic signaling pathwayGO:00971911191.000
regulation of sequence specific dna binding transcription factor activityGO:00510902111.000
immune response activating signal transductionGO:0002757901.000
Human
positive regulation of apoptotic signaling pathwayGO:2001235701.000
toll like receptor 2 signaling pathwayGO:003413441.000
Human
positive regulation of cell deathGO:00109422630.999
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.999
positive regulation of programmed cell deathGO:00430682490.999
regulation of ion transmembrane transportGO:00347651320.999
regulation of apoptotic signaling pathwayGO:20012331750.999
activation of innate immune responseGO:0002218550.999
Human
positive regulation of defense responseGO:0031349870.999
Human
positive regulation of myeloid leukocyte differentiationGO:0002763240.999
cell type specific apoptotic processGO:00972851250.998
Mouse
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557220.998
positive regulation of t cell cytokine productionGO:000272640.998
trail activated apoptotic signaling pathwayGO:003646240.998
apoptotic signaling pathwayGO:00971902680.997
protein polyubiquitinationGO:00002091100.996
positive regulation of nf kappab transcription factor activityGO:0051092810.996
cellular response to tumor necrosis factorGO:0071356630.995
protein modification by small protein conjugationGO:00324463420.995
Human
positive regulation of cellular amino acid metabolic processGO:004576430.994
positive regulation of apoptotic processGO:00430652460.994
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.993
lymphocyte apoptotic processGO:0070227200.992
Mouse
protein processingGO:00164852260.992
positive regulation of phosphorylationGO:00423273940.992
protein oligomerizationGO:00512591730.991
cellular ketone metabolic processGO:0042180800.991
protein maturationGO:00516042330.990
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.989
regulation of defense responseGO:00313471540.988
Human
positive regulation of cellular amine metabolic processGO:003324070.988
cellular amino acid metabolic processGO:00065201160.980
response to cytokineGO:00340972320.979
adaptive immune responseGO:0002250490.979
necroptotic processGO:0070266160.977
ion transmembrane transportGO:00342203380.975
protein ubiquitinationGO:00165673140.973
Human
negative regulation of apoptotic processGO:00430663160.973
protein modification by small protein removalGO:0070646920.973
peptidyl serine autophosphorylationGO:003628920.972
regulation of adaptive immune responseGO:0002819330.972
cytokine mediated signaling pathwayGO:00192211090.972
ubiquitin dependent protein catabolic processGO:00065112060.962
protein heterooligomerizationGO:0051291160.961
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822290.960
modification dependent protein catabolic processGO:00199412090.959
anion transportGO:00068201610.959
protein homooligomerizationGO:00512601000.957
lipopolysaccharide mediated signaling pathwayGO:0031663260.956
negative regulation of nf kappab transcription factor activityGO:0032088510.955
response to biotic stimulusGO:00096072760.954
negative regulation of calcium ion importGO:009028110.950
activation of protein kinase activityGO:0032147900.950
Human
response to tumor necrosis factorGO:0034612760.945
proteolysis involved in cellular protein catabolic processGO:00516032440.944
regulation of protein transportGO:00512232130.942
amine metabolic processGO:0009308440.936
innate immune responseGO:00450871780.935
Human
positive regulation of immune system processGO:00026842830.934
response to oxygen containing compoundGO:19017003690.933
Human
regulation of protein modification by small protein conjugation or removalGO:19033201070.930
Human
regulation of ion transportGO:00432691890.926
protein deubiquitinationGO:0016579790.926
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.926
positive regulation of protein phosphorylationGO:00019343130.923
cellular response to biotic stimulusGO:0071216710.920
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237520.919
response to molecule of bacterial originGO:0002237820.918
response to lipidGO:00339932060.916
immune system developmentGO:00025201950.914
signal transduction by phosphorylationGO:00230142970.908
entry into cell of other organism involved in symbiotic interactionGO:0051806250.904
necrotic cell deathGO:0070265210.903
response to external biotic stimulusGO:00432072610.899
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.899
negative regulation of interleukin 2 secretionGO:190004120.898
cellular response to muramyl dipeptideGO:007122530.894
Human
regulation of lymphocyte activationGO:00512491030.891
activation induced cell death of t cellsGO:000692420.890
regulation of innate immune responseGO:0045088970.888
Human
cellular response to oxygen containing compoundGO:19017012760.886
Human
regulation of cytokine productionGO:00018172320.881
interleukin 2 productionGO:0032623200.879
modification dependent macromolecule catabolic processGO:00436322120.876
cellular response to increased oxygen levelsGO:003629540.875
protein catabolic processGO:00301633250.870
tumor necrosis factor superfamily cytokine productionGO:0071706450.868
regulation of myeloid leukocyte differentiationGO:0002761390.868
myeloid leukocyte differentiationGO:0002573600.867
intrinsic apoptotic signaling pathwayGO:00971931270.866
positive regulation of jak stat cascadeGO:0046427350.865
regulation of reactive oxygen species metabolic processGO:2000377410.865
Mouse
positive regulation of stress activated protein kinase signaling cascadeGO:0070304610.859
regulation of leukocyte apoptotic processGO:2000106250.857
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.853
regulation of proteolysisGO:00301622930.848
positive regulation of necrotic cell deathGO:001094040.841
regulation of peptidase activityGO:00525471800.841
endosomal transportGO:00161971290.839
positive regulation of developmental processGO:00510943140.838
proteasomal protein catabolic processGO:00104981760.833
cellular protein catabolic processGO:00442572610.831
cellular response to cytokine stimulusGO:00713451810.831
response to cobalt ionGO:003202510.829
carbohydrate derivative transportGO:1901264200.829
cellular response to lipopolysaccharideGO:0071222570.825
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555440.824
skeletal muscle satellite cell proliferationGO:001484110.822
regulation of protein processingGO:00706131500.821
regulation of cellular amine metabolic processGO:0033238110.817
regulation of immune responseGO:00507762010.813
Human
regulation of jun kinase activityGO:0043506270.811
lymphocyte homeostasisGO:000226040.810
defense responseGO:00069523150.810
Human
positive regulation of innate immune responseGO:0045089790.803
Human
protein k48 linked ubiquitinationGO:0070936380.803
leukocyte differentiationGO:0002521980.800
cellular response to molecule of bacterial originGO:0071219620.789
cellular response to external stimulusGO:00714961110.787
osteoclast differentiationGO:0030316210.787
cellular response to lipidGO:00713961270.785
regulation of cellular response to stressGO:00801352440.784
response to lipopolysaccharideGO:0032496700.784
negative regulation of protein processingGO:00109551420.780
negative regulation of protein deubiquitinationGO:009008630.766
regulation of mapk cascadeGO:00434082620.765
regulation of immune effector processGO:0002697910.765
positive regulation of tumor necrosis factor productionGO:0032760210.762
protein monoubiquitinationGO:0006513390.760
response to other organismGO:00517072610.756
positive regulation of nik nf kappab signalingGO:1901224100.747
positive regulation of adaptive immune responseGO:0002821210.740
immune response regulating signaling pathwayGO:0002764970.736
Human
regulation of lymphocyte apoptotic processGO:0070228150.736
activation of nf kappab inducing kinase activityGO:000725090.735
regulation of transferase activityGO:00513383550.734
Human Mouse
negative regulation of proteolysisGO:00458611320.732
activation of immune responseGO:00022531140.723
Human
pattern recognition receptor signaling pathwayGO:0002221480.723
Human
t cell differentiation in thymusGO:003307740.721
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625420.717
hemopoiesisGO:00300971800.714
regulation of protein maturationGO:19033171500.705
regulation of protein secretionGO:0050708860.701
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:200005930.699
interferon gamma productionGO:0032609390.698
negative regulation of defense responseGO:0031348470.697
positive regulation of viral entry into host cellGO:004659830.696
regulation of stress activated mapk cascadeGO:0032872840.692
response to bacteriumGO:00096171440.689
positive regulation of neutrophil apoptotic processGO:003303110.674
regulation of atp adp antiporter activityGO:007092610.674
nik nf kappab signalingGO:0038061120.673
regulation of endopeptidase activityGO:00525481700.671
positive regulation of myeloid cell differentiationGO:0045639390.670
regulation of cell differentiationGO:00455953930.665
negative regulation of apoptotic signaling pathwayGO:2001234970.663
protein k63 linked ubiquitinationGO:0070534310.661
t cell proliferationGO:0042098450.660
positive regulation of cytokine productionGO:00018191670.659
positive regulation of cell cycleGO:00457871400.659
leukocyte activationGO:00453211640.658
immune response activating cell surface receptor signaling pathwayGO:0002429450.657
leukocyte apoptotic processGO:0071887310.653
Mouse
positive regulation of osteoclast differentiationGO:004567290.650
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043154460.650
immune effector processGO:00022521590.645
response to virusGO:00096151260.644
negative regulation of cell deathGO:00605483450.639
cellular response to hyperoxiaGO:007145540.631
t cell migrationGO:0072678160.626
positive regulation of macrophage differentiationGO:004565170.622
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192220.621
Mouse
positive regulation of proteolysisGO:00458621420.618
regulation of transmembrane transporter activityGO:0022898740.611
regulation of cellular amino acid metabolic processGO:000652160.609
negative regulation of i kappab kinase nf kappab signalingGO:0043124320.607
regulation of map kinase activityGO:00434051080.606
regulation of intracellular transport of viral materialGO:190125220.604
regulation of cellular ketone metabolic processGO:0010565500.599
regulation of peptidyl tyrosine phosphorylationGO:00507301080.591
Human
negative regulation of protein maturationGO:19033181420.586
negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902042150.583
regulation of interferon beta productionGO:0032648220.580
protein secretionGO:0009306980.577
positive regulation of kinase activityGO:00336742040.576
Human
leukocyte mediated immunityGO:0002443590.571
regulation of nucleoside transportGO:003224210.571
erk1 and erk2 cascadeGO:00703711040.565
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002460400.563
t cell homeostasisGO:004302930.557
positive regulation of mapk cascadeGO:00434101900.552
regulation of interleukin 2 productionGO:0032663190.544
regulation of protein localizationGO:00328802960.544
regulation of t cell proliferationGO:0042129420.542
immune response regulating cell surface receptor signaling pathwayGO:0002768510.535
activation of cysteine type endopeptidase activityGO:0097202570.534
peptidyl serine phosphorylationGO:00181051010.533
positive regulation of cysteine type endopeptidase activityGO:2001056790.529
positive regulation of intrinsic apoptotic signaling pathwayGO:2001244280.525
positive regulation of hair follicle developmentGO:005179830.524
regulation of multi organism processGO:00439001570.523
innate immune response activating signal transductionGO:0002758480.504
Human
amyloid fibril formationGO:199000030.503
interleukin 8 productionGO:0032637510.503
positive regulation of protein kinase activityGO:00458601900.493
Human
ripoptosome assemblyGO:009734310.488
release of cytoplasmic sequestered nf kappabGO:000858840.484
leukocyte migrationGO:00509001070.482
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.481
Human
negative regulation of protein metabolic processGO:00512483910.480
defense response to virusGO:0051607710.477
regulation of necrotic cell deathGO:001093990.471
regulation of lymphocyte proliferationGO:0050670640.468
regulation of viral entry into host cellGO:0046596170.466
zymogen activationGO:0031638700.465
interleukin 6 productionGO:0032635370.458
regulation of mononuclear cell proliferationGO:0032944650.457
regulation of lymphocyte mediated immunityGO:0002706330.453
positive regulation of interleukin 2 productionGO:0032743110.452
regulation of leukocyte differentiationGO:1902105610.452
jnk cascadeGO:0007254800.451
regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902041240.450
regulation of myeloid cell differentiationGO:0045637810.449
negative regulation of protein secretionGO:0050709290.447
regulation of necroptotic processGO:006054470.444
regulation of cell cycle arrestGO:0071156360.443
protein autoubiquitinationGO:0051865370.443
positive regulation of type i interferon productionGO:0032481200.431
response to mechanical stimulusGO:0009612510.420
positive regulation of myeloid cell apoptotic processGO:003303420.400
regulation of macrophage differentiationGO:004564990.400
defense response to bacteriumGO:0042742630.394
endothelial cell apoptotic processGO:0072577260.392
transmembrane transportGO:00550853990.389
positive regulation of map kinase activityGO:0043406800.388
regulation of kinase activityGO:00435493140.388
Human
negative regulation of programmed cell deathGO:00430693210.387
spleen developmentGO:004853610.385
negative regulation of protein ubiquitinationGO:0031397350.384
entry into hostGO:0044409250.383
interleukin 2 secretionGO:007097030.382
nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043140.380
Human
negative regulation of immune system processGO:00026831360.377
nucleobase containing compound transportGO:0015931510.375
protein destabilizationGO:0031648120.365
regulation of myoblast fusionGO:190173910.364
movement in host environmentGO:0052126250.361
myeloid cell differentiationGO:00300991170.360
regulation of cysteine type endopeptidase activityGO:20001161270.348
negative regulation of protein phosphorylationGO:00019331400.341
peptidyl threonine phosphorylationGO:0018107410.341
Human
regulation of cellular extravasationGO:000269180.337
cytokine productionGO:00018162470.336
immune responseGO:00069553070.335
Human
regulation of interleukin 2 secretionGO:190004020.335
positive regulation of endothelial cell apoptotic processGO:200035380.334
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.330
t cell differentiationGO:0030217290.330
regulation of leukocyte activationGO:00026941150.326
intracellular receptor signaling pathwayGO:00305221040.324
Human
negative regulation of endopeptidase activityGO:0010951840.324
regulation of mitotic cell cycleGO:00073461890.323
regulation of tyrosine phosphorylation of stat proteinGO:0042509300.323
negative regulation of interleukin 2 productionGO:003270370.322
regenerationGO:003109940.321
membrane protein ectodomain proteolysisGO:0006509330.319
positive regulation of bindingGO:0051099450.317
regulation of cell cycleGO:00517263930.317
movement in environment of other organism involved in symbiotic interactionGO:0052192250.316
regulation of viral processGO:00507921030.307
regulation of tumor necrosis factor productionGO:0032680430.302
cellular response to mechanical stimulusGO:0071260390.302
cell cycle g1 s phase transitionGO:0044843800.301
positive regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:190204330.299
regulation of angiogenesisGO:0045765920.298
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.298
negative regulation of multi organism processGO:0043901920.298
regulation of protein stabilityGO:0031647870.297
regulation of endothelial cell apoptotic processGO:2000351240.295
viral release from host cellGO:0019076210.288
activated t cell proliferationGO:0050798130.286
negative regulation of viral processGO:0048525660.284
regulation of nik nf kappab signalingGO:1901222110.282
regulation of cell cycle g1 s phase transitionGO:1902806420.279
regulation of t cell mediated immunityGO:0002709180.277
t cell apoptotic processGO:0070231120.275
Mouse
positive regulation of cell differentiationGO:00455972110.274
regulation of stress activated protein kinase signaling cascadeGO:0070302850.273
negative regulation of peptidase activityGO:0010466910.272
regulation of inflammatory responseGO:0050727460.267
positive regulation of leukocyte differentiationGO:1902107370.267
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001239200.265
Mouse
thymus developmentGO:004853830.264
protein trimerizationGO:0070206200.264
positive regulation of t cell mediated immunityGO:0002711120.257
peptidyl serine modificationGO:00182091060.256
retrograde transport endosome to golgiGO:0042147450.253
negative regulation of viral release from host cellGO:1902187120.253
response to interleukin 1GO:0070555470.252
secretion by cellGO:00329402260.252
stress activated mapk cascadeGO:0051403930.250
posttranscriptional regulation of gene expressionGO:00106082130.247
positive regulation of cell activationGO:0050867810.247
regulation of leukocyte proliferationGO:0070663670.243
negative regulation of g1 s transition of mitotic cell cycleGO:2000134290.240
apoptotic mitochondrial changesGO:0008637570.239
androgen receptor signaling pathwayGO:0030521340.239
negative regulation of immune responseGO:0050777400.237
lymphocyte differentiationGO:0030098350.237
response to growth factorGO:00708482050.235
Mouse
negative regulation of response to external stimulusGO:0032102830.231
regulation of viral genome replicationGO:0045069480.231
positive regulation of locomotionGO:00400171860.230
inflammatory responseGO:0006954790.228
regulation of viral release from host cellGO:1902186200.225
positive regulation of oxidoreductase activityGO:0051353260.224
mitotic cell cycleGO:00002783260.224
epithelium developmentGO:00604292270.223
Human
cellular macromolecule catabolic processGO:00442653800.221
negative regulation of t cell apoptotic processGO:007023340.218
regulation of leukocyte mediated immunityGO:0002703380.217
defense response to other organismGO:00985421290.217
positive regulation of rig i signaling pathwayGO:190024640.217
g1 s transition of mitotic cell cycleGO:0000082780.217
mononuclear cell proliferationGO:0032943710.217
secretionGO:00469032540.215
negative regulation of secretion by cellGO:1903531520.215
regulation of t cell cytokine productionGO:0002724100.212
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.212
inflammatory cell apoptotic processGO:000692530.210
cell cycle phase transitionGO:00447701730.210
response to abiotic stimulusGO:00096283360.209
positive regulation of nf kappab import into nucleusGO:0042346130.208
regulation of canonical wnt signaling pathwayGO:0060828880.206
regulation of establishment of protein localizationGO:00702012420.205
regulation of transmembrane transportGO:00347621390.204
regulation of protein kinase activityGO:00458592890.204
Human
positive regulation of interleukin 8 biosynthetic processGO:004541680.202
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001240160.200
Mouse
reactive oxygen species metabolic processGO:0072593750.200
Mouse
negative regulation of intracellular signal transductionGO:19025321830.199
cytoplasmic pattern recognition receptor signaling pathwayGO:0002753120.198
Human
positive regulation of endopeptidase activityGO:0010950840.198
negative regulation of phosphorus metabolic processGO:00105632670.196
regulation of anion transportGO:0044070250.196
negative regulation of cellular protein metabolic processGO:00322693530.195
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:200005870.194
positive regulation of cdc42 gtpase activityGO:004308960.193
regulation of protein deubiquitinationGO:009008540.193
regulation of tyrosine phosphorylation of stat1 proteinGO:0042510110.190
negative regulation of serine type peptidase activityGO:190257220.189
regulation of g1 s transition of mitotic cell cycleGO:2000045400.189
peptidyl tyrosine phosphorylationGO:00181081700.185
Human
regulation of t cell apoptotic processGO:007023280.183
t cell mediated immunityGO:0002456250.183
lymphocyte proliferationGO:0046651700.183
system processGO:00030083490.179
positive regulation of cytokine mediated signaling pathwayGO:0001961120.179
entry into host cellGO:0030260250.179
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.176
Human
regulation of cellular protein catabolic processGO:1903362960.176
tissue regenerationGO:004224630.173
regulation of protein ubiquitinationGO:0031396950.172
Human
type i interferon productionGO:0032606270.167
regulation of osteoclast differentiationGO:0045670180.166
cellular response to oxidative stressGO:0034599850.163
response to endoplasmic reticulum stressGO:0034976490.162
negative regulation of intracellular transport of viral materialGO:190125320.161
negative regulation of cysteine type endopeptidase activityGO:2000117480.160
regulation of protein serine threonine kinase activityGO:00719001790.157
negative regulation of immune effector processGO:0002698380.157
interspecies interaction between organismsGO:00444191560.156
cellular amine metabolic processGO:0044106410.155
regulation of jak stat cascadeGO:0046425440.155
regulation of defense response to virusGO:0050688330.155
regulation of mitotic cell cycle phase transitionGO:19019901180.154
engulfment of apoptotic cellGO:004365220.154
positive regulation of immune responseGO:00507781590.152
Human
regulation of intracellular transportGO:00323861950.151
regulation of interleukin 8 productionGO:0032677490.149
stress activated protein kinase signaling cascadeGO:0031098940.149
entry into other organism involved in symbiotic interactionGO:0051828250.149
nitrogen compound transportGO:00717051910.148
regulation of serine type peptidase activityGO:190257120.148
cellular response to dna damage stimulusGO:00069743790.148
regulation of calcium ion transportGO:0051924790.147
regulation of protein catabolic processGO:00421761550.146
cytokine secretionGO:0050663640.145
tumor necrosis factor productionGO:0032640430.144
negative regulation of catalytic activityGO:00430863350.143
positive regulation of jnk cascadeGO:0046330520.143
antigen receptor mediated signaling pathwayGO:0050851380.142
interferon beta productionGO:0032608230.142
multi organism intracellular transportGO:1902583140.140
cellular response to steroid hormone stimulusGO:0071383370.140
cation transportGO:00068123310.138
positive regulation of protein transportGO:00512221350.136
regulation of transcription regulatory region dna bindingGO:2000677150.136
hematopoietic or lymphoid organ developmentGO:00485341860.136
nucleotide binding oligomerization domain containing signaling pathwayGO:007042340.135
Human
neutrophil apoptotic processGO:000178120.135
regulation of cell motilityGO:20001452990.134
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.134
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.133
regulation of ion transmembrane transporter activityGO:0032412720.132
negative regulation of transportGO:00510511760.132
negative regulation of calcium ion transportGO:0051926190.130
positive regulation of protein catabolic processGO:0045732750.129
necroptotic signaling pathwayGO:009752760.129
multi organism cellular processGO:00447641560.129
nucleocytoplasmic transportGO:00069131760.128
regulation of oxidoreductase activityGO:0051341430.128
response to decreased oxygen levelsGO:0036293960.128
positive regulation of lymphocyte mediated immunityGO:0002708230.128
regulation of peptidyl serine phosphorylationGO:0033135500.127
Human
negative regulation of cytokine productionGO:0001818820.125
positive regulation of peptidyl serine phosphorylationGO:0033138420.124
Human
positive regulation of stress activated mapk cascadeGO:0032874600.122
cellular macromolecular complex assemblyGO:00346223240.122
lymphocyte mediated immunityGO:0002449480.120
regulation of serine type endopeptidase activityGO:190000320.119
t cell activationGO:0042110990.119
regulation of actin filament lengthGO:0030832560.119
nucleotide binding domain leucine rich repeat containing receptor signaling pathwayGO:003587250.119
Human
mitotic cell cycle phase transitionGO:00447721620.118
response to steroid hormoneGO:0048545800.116
long chain fatty acid transportGO:0015909180.115
positive regulation of peptidase activityGO:0010952880.114
regulation of jnk cascadeGO:0046328730.114
regulation of locomotionGO:00400123290.114
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressGO:0070059120.113
regulation of response to biotic stimulusGO:0002831550.112
negative regulation of necroptotic processGO:006054620.112
response to hypoxiaGO:0001666960.111
lymphocyte activationGO:00466491330.109
viral processGO:00160321460.109
regulation of cytokine production involved in immune responseGO:0002718220.109
cellular response to oxygen levelsGO:0071453550.108
regulation of lymphocyte migrationGO:2000401220.108
regulation of reactive oxygen species biosynthetic processGO:190342630.107
negative regulation of secretionGO:0051048580.107
regulation of secretionGO:00510461940.106
regulation of ligase activityGO:0051340290.106
negative regulation of mitotic cell cycleGO:00459301020.106
negative regulation of protein transportGO:0051224750.106
response to hyperoxiaGO:005509340.105
negative regulation of multicellular organismal processGO:00512413170.105
response to nitrogen compoundGO:19016981840.104
Human
lipid transportGO:0006869900.104
t cell receptor signaling pathwayGO:0050852210.104
lymphocyte migrationGO:0072676280.101
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.100
bmp signaling pathwayGO:0030509490.099
regulation of cell cycle phase transitionGO:19019871260.099
regulation of production of molecular mediator of immune responseGO:0002700250.098
negative regulation of viral transcriptionGO:0032897230.098
negative regulation of protein modification by small protein conjugation or removalGO:1903321410.098
protein autophosphorylationGO:00467771230.096
neutrophil degranulationGO:004331230.095
negative regulation of protein kinase activityGO:0006469980.095
cytokine production involved in immune responseGO:0002367270.094
regulation of satellite cell proliferationGO:001484210.094
fibril organizationGO:0097435100.093
regulation of cellular component biogenesisGO:00440872810.091
neurological system processGO:00508771630.091
signal transduction involved in dna integrity checkpointGO:0072401150.090
positive regulation of t cell proliferationGO:0042102330.090
positive regulation of protein bindingGO:0032092240.090
jak stat cascadeGO:0007259460.089
purine ribonucleoside triphosphate metabolic processGO:00092054110.087
tumor necrosis factor mediated signaling pathwayGO:0033209270.087
release of cytochrome c from mitochondriaGO:0001836350.086
positive regulation of cell proliferationGO:00082843010.086
regulation of viral transcriptionGO:0046782340.086
regulation of actin filament polymerizationGO:0030833500.085
cellular response to decreased oxygen levelsGO:0036294510.085
regulation of cell migrationGO:00303342890.085
positive regulation of protein serine threonine kinase activityGO:00719021190.084
mrna metabolic processGO:00160711750.084
establishment of protein localization to organelleGO:00725941720.084
positive regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124140.083
viral gene expressionGO:0019080350.082

RIPK1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:29141550.317
sensory system diseaseDOID:00501552030.278
nervous system diseaseDOID:8634310.278
auditory system diseaseDOID:2742530.221
central nervous system diseaseDOID:3311860.121
autosomal dominant nonsyndromic deafnessDOID:0050564230.111
nonsyndromic deafnessDOID:0050563500.111